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1
Hayes, Angela Elizabeth. "Production of the calcium-dependent antibiotic (CDA) by Streptromyces coelicolor and Streptomyces lividans : molecular biology of cdaR and other genes from the cda cluster". Thesis, University of Manchester, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506567.
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The calcium-dependent antibiotic (CDA) is a non-ribosomally synthesised lipopeptide produced by Streptomyces coelicolor A3(2). The cda biosynthesis gene cluster occupies approximately 83 kb at the 10 o'clock region of the chromosome. A gene encoding a positive regulator of CDA production, designated cdaR, had been previously identified. Sequence similarly suggests that CdaR is a member of the Streptomyces antibiotic regulatory protein (SARP) family. CdaR is predicted to be 638 amino acid residues in size with a putative ATP/GTP-binding site motif A located in its C-terminal region. Mapping of the transcription start point of cdaR found that it possesses an unusually long untranslated leader sequence of 358 nt. cdaR transcripts were easily detectable at the earliest time point examined (24 h) and decreased over time. A 0.75 kb in-frame deletion in cdaR abolished CDA production. Nuclease protection experiments, using RNA isolated from a S. coelicolor cdaR deletion mutant, indicated that CdaR is required for transcription of some of the genes within the cda cluster, including itself. His6-tagged CdaR was produced in E. coli. Preliminary evidence from mobility shift assays suggested that CdaR binds directly to the 5' end of cdaR and also possibly to the promoter region of cdaPSI (peptide synthetase 1). Unexpectedly, introducing multiple copies of cdaR (approximately 50 copies/chromosome) into S. coelicolor 2377 and MT1110 did not detectably increase CDA production. Correspondingly cdaR transcripts only increased by ~ 30% in S. coelicolor MT1110 containing multiple copies of cdaR; this result suggests that transcription of cdaR is very tightly regulated.
2
Kulkarni, Dattatraya H. "CDA, computation decomposition and alignment". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0008/NQ27983.pdf.
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3
Gaeta, Maria Maddalena. "Il procedimento deliberativo del cda di s.r.l". Thesis, Universita' degli Studi di Catania, 2011. http://hdl.handle.net/10761/339.
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La tesi, intitolata, e' Il procedimento deliberativo del cda di s.r.l. ha ad oggetto la verifica circa la sussistenza della eadem ratio per l'applicazione alla s.r.l. delle norme previste per il consiglio di amministrazione della societa' azionaria.
Nel mutato quadro della societa' a responsabilita' limitata, infatti, le regole del procedimento deliberativo del cda, sulle quali il nuovo art. 2475 non interviene espressamente, devono individuarsi e ricostruirsi previa verifica della sussistenza dell'eadem ratio per l'applicazione analogica delle norme che regolano il procedimento deliberativo del consiglio di amministrazione della s.p.a. (artt. 2381-2388) e, dunque, nello specifico, verificando la sussistenza della eadem ratio della collegialita' nell'una e nell'altra societa' anche, ad esempio, rispetto alla logica dei flussi informativi pre-consiliari, necessari nella s.p.a. ma non indispensabili nei modelli convenzionali di s.r.l. piu' aderenti ad una versione, per cosi' dire, personalisticathe thesis, entitled, "The deliberative procedure of the cda of s.r.l." has to object the verification around the subsistence of the eadem ratio for the application to the s.r.l. of the anticipated norms for the board of directors of the stock society. In the changed picture of the responsibility limited society, in fact, the rules of the deliberative procedure of the cda, on which the new art. 2475 don't expressly intervene, you/they must individualize him and to reconstruct him previous verification of the subsistence of the eadem ratio for the analogical application of the norms that you/they regulate the deliberative procedure of the board of directors of the s.p.to. (artt. 2381-2388) and, therefore, in the specific one, also verifying the subsistence of the eadem ratio of the collegiality in the one and in the other society, for instance, in comparison to the logic of the informative flows pre-consiliari, necessary in the s.p.to. but not essential in the conventional models of s.r.l. more adherent to a version, for so to say, personalistica.
4
George, Stephen J. "Community of Inquiry Meets Critical Discourse Analysis (CDA): A CDA of Asynchronous Computer-Conference Discourse with Seminary Students in India". Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1011816/.
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The purpose of this study was to better understand student learning in asynchronous computer-conference discourse (ASD) for non-native speakers of English in India through the Community of Inquiry (COI) framework. The study looked at ASD from an online course taught in the fall of 2015 to 25 students in a seminary in South India. All but one of the students were non-native speakers of English. The class consisted of 22 men and 3 women. Eight students spoke languages from the Dravidian family of languages (Malayalam, Tamil, Telegu and Kannada). Eight students were from the Northeastern states of Manipur, Nagaland and Tripura, where most languages are from the Sino-Tibetan family. Three students were native speakers of Indo-Aryan languages (Odiya and Assamese). Five students were from Myanmar representing several Sino-Tibetan languages. The COI is a framework used to understand learning in ASD, often used in online learning. To study the ASD of this group, critical discourse analysis (CDA) was used with the COI to capture the unique socio-cultural and linguistic conditions of this group.
The study revealed that non-native speakers of English often reach the Exploration phase of learning but rarely show evidence of reaching the Resolution phase. This phenomenon was also observed in native English speakers as reported in the literature. Also, the structure of ASD showed that students took an examination approach to discussion shaped in part by their epistemology. This examination approach shaped how knowledge was constructed. CDA also showed that the discourse acquired an instructor-centered structure in which Resolution and Repair were initiated and finalized by the instructor.
The study advances the COI framework by undergirding it with a theory of asynchronous discourse using critical discourse analysis and capturing cognitive, social and teaching presence phenomena for non-native speakers that were not observed through the traditional COI framework. These phenomena were driven by cultural, epistemological, and linguistic forces and require a rethinking of the COI for contexts outside of North America. The study also demonstrates that learning for non-native speakers in ASD is challenged by these very same forces. Therefore, design for online learning should account for these phenomena.
5
Ellece, Sibonile Edith. "Gendered Marrige Discourses in Botawana : A CDA Approach". Thesis, Lancaster University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507051.
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FARINA, VINCENZO. "Ruoli ed efficacia del Cda degli intermediari finanziari". Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/1041.
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Un sistema di governance può essere definito come un sistema coerente ed articolato di regole, di strutture e di processi, che assicura la direzione, il controllo e l’accountability delle imprese. Negli ultimi anni il miglioramento dei sistemi di governance è divenuto un obiettivo prioritario nella convinzione che essi possano contribuire ad aumentare la performance aziendale e che l’efficacia della governance dipenda in buona misura dalla qualità della struttura e dei meccanismi decisionali dei Cda.
Le impostazioni prevalenti negli studi sui Cda riconoscono la necessità di contemperare le esigenze di composizione e rappresentazione degli interessi dei diversi stakeholder, enfatizzando la possibilità di ridurre i costi di agenzia. Una prospettiva complementare considera l’acquisizione ed il controllo delle risorse critiche strettamente correlati all’attivazione di relazioni con gli attori più influenti del proprio network. All’interno di questa prospettiva si afferma l’elevato potere istituzionale degli intermediari finanziari in virtù del maggiore controllo della risorsa critica rappresentata dal capitale.
Il lavoro si pone l’obiettivo di verificare l’ipotesi di una relazione positiva fra potere istituzionale e performance degli intermediari finanziari e si inserisce all’interno dell’ultima prospettiva di ricerca contribuendo al suo arricchimento, sia sul piano dei contenuti sia su quello degli strumenti utilizzabili.
Sul piano dei contenuti, sono ancora limitati gli studi che analizzano i legami fra potere istituzionale e performance nella prospettiva delle relazioni (Cotter, Shivdasani, Zenner 1997; Brown, Maloney 1999; Davis, Mizruchi 1999; Miwa, Ramseyer 2000; Ferris, Jagannathan, Pritchard 2003) e solo pochi fra questi prendono in considerazione gli intermediari finanziari. Sul piano degli strumenti, il lavoro si distingue per l’applicazione della social network analysis (Mitchell 1969; Wasserman, Faust 1994) per la misurazione del potere istituzionale degli intermediari finanziari, inteso come la centralità nel network degli interlocking directorates, ossia i legami tra società quando una stessa persona è membro dei rispettivi Consigli di amministrazione.
A livello di risultati emergono due evidenze: i) gli intermediari finanziari sono effettivamente gli attori che detengono il maggior potere istituzionale nel network degli interlocking directorates che essi formano con le imprese del campione analizzato e costituito da 255 società quotate su Borsa Italiana Spa nel 2006; ii) il contributo dato dalla qualità delle relazioni (misurata attraverso l’indicatore della betweenness o centralità) alla performance è positivo e significativo.Corporate governance can be defined as an articulated system of rules, structures and processes aimed to assure the management, the control and the accountability of firms. During the last few years the improvement of governance systems has become a priority objective due to the conviction that these systems can contribute to increase performance which is firstly based on the effective functioning of boards of directors (BoDs). Main studies on the BoDs recognize the necessity to represent the interests of stakeholders, emphasizing the possibility to reduce agency costs. A complementary perspective considers the acquisition and the control of the critical resources closely related to the activation of relations with the more influential actors of the network. In this view, financial intermediaries have the greater institutional power due to their larger control of capital flows. This work’s purpose is to verify the hypothesis of a positive relationship between institutional power and performance of financial intermediaries, taking into consideration the last perspective, contributing to its enrichment, both on contents and tools of analysis levels. Regarding the contents, studies that analyze the relationships between institutional power and performance in the perspective of governance relations are still limited (Cotter, Shivdasani, Zenner 1997; Brown, Maloney 1999; Davis, Mizruchi 1999; Miwa, Ramseyer 2000; Ferris, Jagannathan, Pritchard 2003) and only few of these take into consideration the financial intermediaries. Regarding the tools of analysis, this work is distinguished for the application of social network analysis (Mitchell 1969; Wasserman, Faust 1994) for the measurement of the institutional power of the financial intermediaries (i.e. the centrality in the network of the interlocking directorates). From results emerge two evidences: i) financial intermediaries are effectively the actors with the greater institutional power in the network of the interlocking directorates referred to a sample of 255 firms listed on Borsa Italiana Spa in 2006; ii) the contribution given from the quality of the relationships to the performance is positive and significant.
7
Aldadah, Yasmin. "CDA analysis of Jerusalem Conflict in BBC and AJE". Thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-67498.
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This research aims at finding how BBC and AJE media represented the Israeli-Palestinian conflict. The study examines the news website, which reported the recent escalation of Jerusalem conflict in December 2017, where US President Trump have recognized Jerusalem as Israeli capital, and declared to move the US embassy from Tel-Aviv to Jerusalem. The study uses qualitative research, where it investigated the impact of ideology on media discourse by means of critical discourse analysis (DHA, Topoi, and Social actor’s representation). CDA was carried out for a sample of 8 news articles published on the websites of two networks: the British Broadcasting Corporation World news "BBCWN" and the Middle Eastern Qatari owned "Al Jazeera English". The articles were chosen within the month of December 2017. Articles were analyzed by means of the two-level analysis method, including the thematic and in-depth analysis. On the first, entry-level analysis, I focus on contents of texts and outline the discourse topics. While in the second phase I analyze the means of discursive strategies and the representation of social actors utilized throughout the text. The thematic analysis revealed that, both BBC and AJE have covered the incident similarly in general look. However, in-depth analysis showed that each network had portrayed the images of Israelis and Palestinians differently. On contrast of AJE, BBC tends to perceive Palestinians as a threat and the Israeli one as victims of the Palestinian violation. Moreover, the analysis revealed that each network had different ideologies and aims. The study concludes that AJE articles was biased pro-Palestinians, while BBC articles was biased pro-Israelis.
8
Matuschek, Andreas [Verfasser]. "Epidemiologie der Kongenitalen Dyserythropoietischen Anämie (CDA) in Europa / Andreas Matuschek". Ulm : Universität Ulm. Medizinische Fakultät, 2013. http://d-nb.info/1032243716/34.
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Napel, Hans-Martien Thijs Dominique ten. "Een eigen weg : de totstandkoming van het CDA (1952-1980) /". [S.l. : s.n], 1992. http://catalogue.bnf.fr/ark:/12148/cb37147399r.
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Liljeholm, Maria. "Congenital Dyserythropoietic Anemia type III (CDA III) : diagnostics, genetics and morbidity". Doctoral thesis, Umeå universitet, Institutionen för strålningsvetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-117454.
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The Congenital Dyserythropoietic Anemias (CDA) are rare hereditary hemolytic disorders with large bi- to multi-nucleated erythroblasts in the bone marrow. Hemolysis is negative in a direct antiglobulin test (DAT). Based on morphology and clinical picture, three major forms of CDAs, type I, II, and III have been defined. CDA III, dominantly inherited, constitutes the rarest type with a majority of cases belonging to a family in Västerbotten, Sweden. The genetic background of CDA I and CDA II has been linked to mutations in CDAN1 and SEC23B respectively. The mutation of CDA III has been linked to 15q22 in earlier studies. In this project we have defined the causative genetic lesion in two families with CDA III. The novel mutation KIF23 c.2747C>G (p.P916R) was shown to segregate with CDA III in the Swedish and American CDA III families and was absent in 356 healthy controls. KIF23 encodes mitotic kinesin-like protein 1 (MKLP1), which plays a central role in the last step of cytokinesis. RNAi-based knock-down and rescue experiments demonstrated that the p.P916R mutation causes cytokinesis failure in HeLa cells, resulting in increasing number of bi-nuclear cells, consistent with appearance of large multinucleated erythroblasts in CDA III patients. We conclude that CDA III is caused by a mutation in KIF23, encoding MKLP1, a conserved mitotic kinesin crucial for cytokinesis. Flow cytometry with eosin-5´-maleimide (EMA), anti-CD55 and anti-CD59 is commonly used when investigating non-autoimmune hemolytic anemias. Reduced fluorescence of EMA, typically detected in hereditary spherocytosis, is also seen in CDA II, while reduction of CD55 and CD59 characterizes paroxysmal nocturnal hemoglobinuria (PNH). We studied the flow cytometric profile of EMA, CD55, and CD59 on erythrocytes in CDA III. We found no abnormality of the erythrocyte membrane in CDA III and concluded that standard flow cytometry cannot be used to discriminate between CDA III and normal controls. In CDA I and CDA II a majority of patients, including those who are not transfusion dependent, suffer from iron overload, which, according to earlier studies, is not the case in CDA III. We found that individuals of the Västerbotten CDA III family carry mutations in the hemochromatosis (HFE) gene. Three CDA III patients with heterozygous or compound HFE mutations need treatment with phlebotomy due to iron overload. One of them carries heterozygous H63D mutation, which is not reported to lead to iron overload by itself in otherwise healthy individuals. We propose that molecular genetic testing of the HFE gene is indicated in all patients with CDA, including CDA III.
11
Shi, Jiayi. "English language education policy in China : a CDA and ethnographic study". Thesis, University of Newcastle upon Tyne, 2016. http://hdl.handle.net/10443/3355.
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Despite the growing stream of literature about English language education in China, there has been relatively little discussion of primary English language education. Past research has focused almost exclusively on secondary and tertiary English education. This research seeks to address this gap by examining primary English education policy. More specifically, this research provides insights into the extent to which each instance of language policy and planning can be seen as a product of its specific context. This thesis is based on an ethnographic study conducted in local education bureaus and three primary schools in Yulin, a Northwestern Chinese city with 3 million people. Drawing on critical discourse analysis (CDA) of political discourse(s), ethnographic field notes, questionnaires, interviews and classroom observation, this study investigates the influence of macro and micro levels of policy actors in disseminating and implementing the language policy. It also evaluates the apparent match and mismatch between macro policy and micro levels of practice within the local language policy and planning context. As such, I offer a lens for studying primary English education policy in China. The combination of critical discourse analysis (CDA) and ethnography represents a methodological contribution of this research and is used as a way of seeing if there are gaps between policy and practice; and, if so, what kind(s)? Thus, the main contribution of this study to the literature on language education policy is a framework for analyzing the interaction between policy and practice. This framework combines CDA and ethnography. CDA is used to try and identify underlying ideology and power relations in politically determined educational discourse, whereas the ethnographic part of the study is used to examine and interpret the implementation of policy among local education officials and teachers. Additionally, this research extends the current literature on English education policy by identifying that a lack of communication between macro and micro policy actors is a significant reason behind poor English language education quality. On the surface, local officials and teachers follow the instructions in the political discourse, due to a somewhat rigid hierarchical structure of Chinese society. In some aspects, though, local officials and teachers might veer away from, abandon or even change policy consciously or unconsciously in their daily routines and classes. Importantly, the findings presented in this thesis try to bridge the research on language education policy and teaching and content and methods.
12
Weitz, Lesley Anne. "A fast-time study on increasing the capacity of continuous descent approaches through airborne precision spacing". Texas A&M University, 2005. http://hdl.handle.net/1969.1/2508.
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Due to projectedincrea ses in air traffic, there are several research efforts underway
to evaluate ways to safely increase the capacity of the National Airspace System
(NAS), improve operational efficiency, andre duce aircraft noise. At NASA Langley
Research Center (LaRC) in Hampton, Virginia, two parallel research efforts have focusedon
terminal area research: one is Airborne Precision Spacing (APS), and the
other is the Quiet Aircraft Technologies (QAT) project. The APS objective is to
increase terminal-area capacity without adversely affecting safety, whereas the QAT
project objective is to develop noise- and fuel-efficient approach trajectories.
The APS project developed a cockpit tool, called Airborne Merging and Spacing
for Terminal Arrivals (AMSTAR), that issues speedco mmands to aircraft to maintain
desired spacing between aircraft pairs. The APS studies showed an ability to
increase runway capacity; however, capacity increases may negatively impact noise
andemissio n levels in airport areas. The QAT project created efficient Continuous
Descent Approaches (CDAs), which showedred uctions in aircraft ground noise and
fuel consumption. Previous research has shown that CDA trajectories have adverse
effects on runway capacity because aircraft must be spacedf urther apart at long distances
from the runway to prevent separation losses at the runway threshold. To
date, the APS and CDA concepts have been evaluated independently at LaRC.In this study, three different approaches to combining APS and CDA operations
were evaluatedto determine the feasibility and benefits of combining these concepts.
These methods combined AMSTAR with 3◦-flight-path-angle-CDA approach routes,
3◦-CDA routes with spoilers, and2 ◦-CDA routes without spoilers. Adding the use
of spoilers allowedf aster responses to large speedr eductions issued by AMSTAR.
This improvement was contrastedwith the effects of a shallower flight-path angle for
greater deceleration capabilities.
This research indicated that AMSTAR improved the performance of CDA operations,
although full capacity improvements were not achieved. Whereas the 2◦-CDA
routes were expectedto show the best results, the 3◦-CDA case with spoilers showed
the least variability in thresholdspacing errors. All of the CDA routes were more
noise, fuel, and time efficient than traditional step-descent routes that are commonly
usedto day.
13
Larsson, Elin y Anna Löf. "Om Världen - ett bidrag till förändring? : C-uppsats inom medier, journalistik och kommunikation". Thesis, Stockholms universitet, Institutionen för mediestudier, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-78386.
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Denna C-uppsats granskar OmVärlden som behandlar bistånd, utveckling och globala frågor och som ställs till förfogande av Sida (Styrelsen för internationellt utvecklingssamarbete). Studien grundar sig i ett övergripande intresse för hur medierna påverkar samhällets uppfattning om verkligheten och för studien relevant, postkoloniala föreställningar om maktrelationer och strukturer i utvecklingsländer. Studien innefattar en förstudie i kombination med kritisk diskursanalytisk metod vilken appliceras på fem skilda reportage ur OmVärlden. Syftet är vidare att se hur journalistiska texters uppbyggnad bidrar till att konstituera samhällets föreställningar om rådande hegemoniska strukturer. För att definera studiens problemområde ställs frågor om reportagens dominerande teman och aktörer samt representationen av genus. Detta följs sedan av en utredning av Sidas eventuella röst och påverkan vad gäller OmVärldens redaktionella innehåll. För studien relevant har ett flertal teorier och begrepp behandlats, bland annat postkolonial teori (som berör kritisk granskning av hierarkiska maktrelationer) och intersektionalitet (som bidrar med att skapa förståelse för hur simultana och globala maktrelationer påverkar föreställningar om ojämnlikhet). Efter redovisning av samtliga anlyser och med stöd från behandlade teoretiska områden, gör vi tolkningen att reportagens tematiska och diskursiva sammansättning styr de postkoloniala maktförhållandenas produktion och reproduktion. Vidare konstaterar vi att Sidas röst framkommer genom, och därmed påverkar OmVärldens redaktionella innehåll. Vi drar följdaktligen slutsatser som grundar sig i analysens resultat om textsammansättningens utformning och betydelse. Vi tolkar resultaten som att OmVärlden explicit bidrar med en betydelsefull och nutida angelägen kunskap om utvecklingsländer och bistånd, vilket i enhet med Sida verkar för utveckling inom området. Tidningens implicita bidrag till en ideologisk omvärldsförändring tolkas dock som begränsad. Avslutningsvis behandlas ett flertal aspekter vad gäller fortsatt forskning inom ämnesområdet.
14
Milne, Claire E. "Biosynthesis and engineered biosynthesis of Calcium Dependent Antibiotic (CDA) from streptomyces coelicolor". Thesis, University of Manchester, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506586.
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Calcium Dependent Antibiotic (CDA), is a nonribosomal lipopeptide antibiotic from Streptomyces coelicolor. It is an undecapeptide with an unusual N-terminal 2,3-epoxyhexanoyl fatty acid side chain. It contains many nonproteinogenic amino acids such as D-4-hydroxyphenylglycine, D-3-phosphohydroxyasparagien, L-3-methylglutamic acid and Z-2,3-dehydrotryptophan. CDA is very similar in structure to the antibiotic daptomycin, which under the trade name Cubicin has recently been approved for the treatment of skin infections. The work described in this thesis focuses on a number of different areas, with the overall aim of delineating the biosynthetic origin of CDA and investigating the possibility of producing modified cyclic lipopeptides through a combined chemical and biochemical approach. Strategies used in engineering the biosynthesis of CDA may then be applied to other related, nonribosomal peptides of therapeutic importance, in order to improve their biological activity.
15
Urrutia, Beiza Ricardo. "CDA: Centro de Difusión Astronómica Universidad de Chile: Observatorio Astronómico Nacional Cerro Calán". Tesis, Universidad de Chile, 2012. http://www.repositorio.uchile.cl/handle/2250/112595.
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ArquitectoNo autorizada por el autor para ser publicada a texto completo
El Cerro Calán actualmente es propiedad de la Universidad de Chile y alberga las instalaciones del Observatorio Astronómico Nacional, que ha funcionado por más de 150 años , pero que muy pocos saben de su existencia. Este proyecto consiste en plantear un Centro de Difusión Astronómica en uno de los tantos terrenos que actualmente están desperdiciados y que son parte del patrimonio de la Universidad de Chile. El proyecto consiste en una “placa” que aloja el programa arquitectónico propuesto para el proyecto; tal como salas de exposiciones, talleres, auditorio o un planetario entre otros; y se adhiere a la cúpula mayor del Observatorio Astronómico reciclando este edificio actualmente en desuso.
16
Ko, Wing-shum y 高穎森. "The Asian American voice: a Critical Discourse Analysis (CDA) approach to rap lyrics". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46960235.
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Rapping has long been used by people who are from the margin of society as a way to give a voice (Campbell, 2005; Ibrahim, 1999). As a member of the marginalized group and as the first and only Asian who claimed a seven-time victory on Freestyle Friday on Black Entertainment Television (BET), Jin Au-Yeung has received a noticeable amount of attention. At the same time, he has faced a lot of unfavourable experience as an Asian rapper in American society. This study employs Fairclough’s (1989) model of CDA approach to find out how Jin constructs his identity and establishes his ideology through his lyrics, and how his construction of identity and establishment of ideology reflect the social practice in American society. Fifteen songs written by Jin were chosen for the analysis according to the three interrelated stages in CDA: description, interpretation and explanation. Results show that Jin constructs his personal identities as a professional rapper and as a Chinese American and establishes his ideology of having one human nation despite the difference in races through his rap lyrics. These are achieved through the co-occurrence of “I” and “to be”, and promoted through the use of rhyming and code-switching. It was also interpreted that Jin’s personal identities and ideology are shaped through the social ideology on Asian Americans, which is probably reflected through the social practice in American society.published_or_final_version
Applied English Studies
Master
Master of Arts in Applied Linguistics
17
Brière, Stéphan C. "Selection of partial resistance for crown rust (Puccinia ćoronata Cda.) race 264 in oat". Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60678.
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Nineteen cultivars and fourteen breeding lines were evaluated for partial resistance to crown rust Puccinia coronata race 264. Multivariate statistical methods such as principal component and cluster analyses were employed to identify significant resistance parameters and to group oat genotypes with similar rust resistance characteristics. This involved two separate investigations consisting of two experiments each, the first experiment conducted under field conditions and the second conducted under growth bench conditions. From both of the investigations a group of oat genotypes with high partial resistance to P. coronata race 264 was obtained. These are OA 712-17, OA 712-33, Glen, Woodstock, QO 220.13, and QO 574.21. These oat genotypes are currently being used as parents in crosses in the Macdonald Campus of McGill University oat breeding program.
18
Keppler, Uta [Verfasser]. "Epidemiologie der Kongenitalen Dyserythropoetischen Anämie (CDA) in Amerika, Asien, Australien und Neuseeland / Uta Keppler". Ulm : Universität Ulm, 2018. http://d-nb.info/117324980X/34.
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Zwart, Rutger Simon. ""Gods wil in Nederland" : christelijke ideologieën en de vorming van het CDA (1880-1980) /". Kampen : uitg. Kok, 1996. http://catalogue.bnf.fr/ark:/12148/cb40138506n.
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Gonzaga, Jair João. "Experimenting with SFL as a tool for CDA in a secondary school classroom environment". Florianópolis, SC, 2006. http://repositorio.ufsc.br/xmlui/handle/123456789/88298.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura CorrespondenteMade available in DSpace on 2012-10-22T07:28:29Z (GMT). No. of bitstreams: 1 233492.pdf: 1715444 bytes, checksum: ee61e41d6738d478da6a067a70f4b939 (MD5)
Nesta pesquisa, eu investigo se, e de que maneira a utilização da Lingüística Sistêmico-Funcional (LSF) em ambiente de escola secundária pode contribuir para fazer alunos do ensino médio lerem com visão crítica, i.e., se essa teoria pode melhorar a percepção desses alunos em relação às escolhas lingüísticas utilizadas como #códigos de significação# (Meurer, 2004, 2006) em #práticas discursivas# (Fairclough, 1992a), e se torna-os mais conscientes de suas posições sociais em relação a suas estruturas sociais, de maneira a poderem repensar suas práticas sociais, especialmente no que se refere a fazer análises de textos sob uma perspectiva da Análise Crítica do Discurso (ACD).
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CARPI, FRANCESCO MARTINO. "Human Cytidine Deaminase (CDA): uncovering the physiological role through its functional genetic polymorphism K27Q". Doctoral thesis, Università degli Studi di Camerino, 2011. http://hdl.handle.net/11581/401871.
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In light of the potential crucial role of CDA polymorphisms in the development of individual therapies designed to maximize response and minimize non-therapeutic side effects, we investigated first of all the CDA polymorphic distributions in healthy individuals from population of central Italy. At this purpose, we developed three polymerase chain reaction (PCR)-based methods for CDA 79AmajorC (K27Q) and CDA 208GmajorA (A70T) genotyping. Until now, these SNPs in the CDA gene have been genotyped by allelic discrimination using a TaqMan assay, or by direct sequencing or by High-resolution melting (HRM) analysis of polymerase chain reaction amplicon [...]. A RFLP (restriction fragment length polymorphism) method using RsrII as restriction enzyme was described only for A70T [...]. Our PCRbased assay [Allele Specific (AS-PCR) and Restriction Fragment Length Polymorphism (RFLP-PCR)] does not require any special equipment, and it provides rapid, reproducible, and cost effective detection of common CDA mutations. It can be carried out efficiently in a standard molecular genetics laboratory and suitable as a preliminary screen for all patients. Furthermore, we performed a new discontinuous direct HPLC assay to assess the cytidine deaminase activity from whole blood of individuals enrolled in this study, correlating it with CDA K27Q genotypes. Since genetic factors are thought to be responsible for up to 50-60% of the rheumatoid arthritis liability [...] in collaboration with Division of Rheumatology, Catholic University of the Sacred Heart (Rome, Italy), we have tested the genetic association between functional polymorphism of CDA (K27Q, rs2072671) and RA by case-control study. Finally, using mutated recombinant proteins, we performed a kinetic and molecular study on the two functional variants Q27 and K27, assessing the biochemical properties of CDA Q* and K* alleles.
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Andersson, Alexandra. "Kvinnan och tjänsten : En kritisk diskursanalys av det svenska rättsväsendets framställning av kvinnor som befinner sig i prostitution". Thesis, Mälardalens högskola, Akademin för hälsa, vård och välfärd, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-43335.
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The representation of women in prostitution varies over time and space. This study aims to make visual how women in prostitution are being represented in Swedish judicial system today. The study uses a critical discourse analysis, inspired by Fairclough's three-dimensional model, and is based on a theoretical framework of reification theory, theory of respectability and previous research. The study analyzes 68 court verdicts, published in 2018 on the legal database Karnov Juridik, Kvinnifridspropositionen (Prop. 1997/98: 55) and an evaluation of the law's application and effect (SOU 2010: 49). The study makes visible a two-part image of the woman as occasionally invisible and occasionally defined on the basis of prostitution. The study shows how an overall market discursive perspective through the verdicts relates to a focus on the purchase of sex, rather than the parties involved. The study shows that the focus on the woman in prostitution, which was widely criticized and which the law reform intended to shift towards the sex buyers, continues to stay on the women in prostitution.Framställningen av kvinnor som befinner sig i prostitution har varierat över tid och rum. Denna studie ämnar undersöka hur svenskt rättsväsende framställer kvinnor i prostitution idag. I studien används en kritisk diskursanalys, inspirerad av Faircloughs tredimensionella modell, och utifrån ett teoretiskt ramverk av reifikationsteori, respektabilitetsteori samt tidigare forskning. Studiens empiriska underlag utgörs av 68 domar, publicerade år 2018 på rättsdatabasen Karnov Juridik, kvinnofridspropositionen (Prop. 1997/98:55) och en utvärdering om lagens tillämpning och effekt (SOU 2010:49). I studien synliggörs en tudelad bild av kvinnan som tidvis osynlig och tidvis definierad utifrån prostitution. Studien synliggör hur ett marknadsdiskursivt perspektiv genom domarna påverkar diskursen genom att fokus riktas mot den sexuella tjänster mot ersättning, snarare än de parter som är involverade. Det kritiserade fokus som tidigare inriktades på kvinnan i prostitution ämnade lagreformen att skifta mot männen, sexköparna. I studien framkommer tendenser av ett fortsatt fokus på kvinnorna som befinner sig i prostitution snarare än sexköparna, som framställs som konsumenter inom ett marknadsfenomen.
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Grömmer, Angela. "2-CDA-Therapie bei 8 Patienten mit Haarzell-Leukämie im Klinikum rechts der Isar, München". [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=963682709.
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Ng, Yick-hung Christy. "Comprehensive development area (CDA) zoning in Hong Kong a probit analysis of planning application statistics /". Click to view the E-thesis via HKU Scholars Hub, 2006. http://lookup.lib.hku.hk/lookup/bib/B37943340.
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Chandini, Murarilal Ratnadevi. "Molecular Characterization of arsC gene involved in accumulation of arsenics in Lysinibacillus sphaericus B1-CDA". Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13026.
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Dulioust, Anne. "Effet du PAF-acéther sur l'activation des lymphocytes T humains CDA+ induite par la phytohémagglutinine". Paris 7, 1989. http://www.theses.fr/1989PA072203.
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Sliesarieva, Anna. "The Defender vs. the Censor: CDA Analysis of 2017 Russian Web-Source Ban in Ukraine". Thesis, Uppsala universitet, Institutionen för informatik och media, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-414735.
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With the new challenges of the digital world associated with disinformation, data breaches, and cybercrimes (Cadwalladr & Graham-Harrison, 2018; Connolly et al., 2016; Shipley & Bowker, 2013) many countries nowadays discuss approaches to Internet regulation. In Ukraine, which faced propaganda tactics employed by Russia as a part of the Ukrainian-Russian conflict (Yurkova, 2018), the need for information security in recent years became a major challenge. In 2017, authorities of Ukraine addressed the challenge by introducing sanctions to the most-used Russian web-platforms, including social networks Vkontakte and Odnoklassniki, search engine Yandex, and many other services. This study analyzed the discourse that was formed around the decision. The work incorporates the model of critical discourse analysis by Fairclough (1995a) and framing analysis by Pan & Kosicki (1993). This qualitative study analyzed materials from Ukrainian online media, TV stories, user comments, and political speeches from 16th-17th May 2017 – the dates when the decision on blocking of Russian web-sources was announced to the Ukrainian public. The research answers the questions about the dominant discourses in society regarding the approach of the authorities to Internet regulation, the main arguments and counter-arguments, and media framing. The results show that the discussion was locked in a trap of two dominant discourses of freedom of speech and national security, whereas alternative measures to restrictions were not represented on the public agenda.
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Jonsson, Helena y Andersson Catrine Persdotter. "Bortom kjoltyg och byxhängslen : En eklektisk genusanalys av serietidningen Bamse". Thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-29622.
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This study has the purpose to reveal whether gender stereotypes are manifested or challenged in the children comic Bamse - världens starkaste björn based on six different stories widespread over 40 years. The results will be studied in the light of the contemporary gender development in society and emanate from theories about power, discourse, representation, queer and gender. An eclectic analysis based on semiotics and critical discourse analysis will be the method to reveal the underlying gender perspective in Bamse. The conclusion of the study shows an ambiguous perspective in the comic where both men and women occasionally are represented in a manifested as well as a challenged stereotypical role. In some of the stories the gender is erased and all characters are represented based on their individual attributes instead, meanwhile in some stories men are represented as active heroes while women are portrayed as passive nurturer. The representations are getting better over time and the latest stories from 2005 and 2013 tend to show a development in the gender issue.
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Vallingstam, Edward. "Synd och syndare : En kritisk diskursanalys av HBTQ-personers representation i Kyrkans Tidning, Dagen och Världen Idag". Thesis, Stockholms universitet, Institutionen för mediestudier, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-117996.
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Syftet med denna uppsats är att undersöka representationen av HBTQ-personer i kristna nyhetstidningar i Sverige. Frågeställningen innefattar hur dessa representeras, vilka som representerar dem och hur representationen förhåller sig till Rainer Forsts toleranskriterier. Materialet består av opinionsmaterial från Kyrkans Tidning, Dagen och Världen Idag, och i analysen behandlas artiklar från år 2009 och 2014. För att undersöka representationen har jag har gjort en kritisk diskursanalys utifrån Fairclough. Jag har även lyft in teorier om stereotypisering av Stuart Hall och Richard Dyer, representation av HBTQ-personer av Shiri Eisner och könsnormer av Judith Butler. Artiklarna har delats in i pro- och kontraartiklar. Analysen visar att pro-artiklarna saknar sanningsanspråk, vilket visar en inkluderande attityd. Kontraartiklarna fokuserar på den egna tolkningen som den enda rätta, vilket genererar en auktoritär attityd som betraktar den homosexuelle som syndare så länge personen lever ut sin homosexualitet. De tenderar även att se det sekulära samhället som hotfullt och skapar en stereotyp av HBTQ-gruppen som högljudd och krävande. Denna stereotyp är som tydligast år 2014. Pro-artiklarna välkomnar människor av olika sexuella läggningar medan kontraartiklarna ser den heterosexuella läggningen som den enda av Gud givna, naturliga och önskvärda läggningen. Ledarartiklarna avgjör tidningens officiella ställningstagande och analysen visar att Kyrkans Tidning är mest tillåtande. HBTQ-gruppen representeras dock endast av homosexuella i samtliga tidningar. Världen Idag är den enda tidningen som saknar pro-artiklar och lever därav inte upp till Forsts toleranskriterier. Kyrkans Tidning kan placeras i värdesättningsuppfattningen och Dagen i tillåtelseuppfattningen.
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Ceder, Madeleine. "Från läderbögar till färgglad stolthet : En kritisk diskursanalys av Prideparaden i Dagens Nyheter och Aftonbladet". Thesis, Stockholms universitet, Institutionen för mediestudier, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-100029.
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Studiens syfte är att undersöka hur Stockholms Prideparad representeras i Dagens Nyheter och Aftonbladet åren 1998, 2009 och 2013. Frågor som ställs är vilka diskurser som används i rapporteringen av paraden, samt vilken kunskap om sexualitet som reproduceras och genereras i artiklarna. Studien utgår från Michel Foucaults teorier om kunskap, makt och sexualitet; Norman Faircloughs diskursteori; samt queerteori. En kritisk diskursanalys enligt Faircloughs tredimensionella modell tillämpas på materialet som utgörs av sex stycken artiklar, en för varje tidningen och utvalt år. Analysen av artiklarna visar att de dominerande diskurserna i båda tidningarna var en event-/nöjesdiskurs som sammanfattar paraden. Skillnaderna är större mellan artiklarna från olika år än mellan artiklarna från olika tidningar. Samtliga artiklar reproducerar en heteronormativ ideologi: under 1998 sker det genom exkludering enligt heteronormens första princip och tydlig åtskillnad av deltagare och åskådare. 2009 och 2013 har sexualitetsdiskursen förändrats, och reproducering sker genom assimilering av hbtq-gruppen. I slutdiskussionen betonas paradoxen kring benämningen av hbtq-personer som å ena sidan bidrar till uppfattningen av heterosexualitet som norm, men å andra sidan synliggör hbtq-gruppen.
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Kwok, In-wai y 郭妍慧. "Development control and development process : a study on comprehensive development area (CDA) zone in Hong Kong". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206578.
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There is growing interest in the impact of development controls on the development process. Many researches focus on whether development controls offer certainty and flexibility to developments. Nevertheless, not many researches explore the causes leading to delays in developments. Through examining the length of time spent in the stages of planning, lease and building controls of 57 completed Comprehensive Development Area (CDA) sites where the development processes were started and completed in the Metro Planning Committee Area in Hong Kong between 1990 and 2014, this paper explores if there are any factors accounting for the delay in the development process of the completed CDA sites. Besides, this research examines the relationships between the length of time involved in the development process and the characteristics of the completed CDA sites. Meanwhile, this research also examines 67 approved planning applications submitted for uncompleted CDA sites where the development processes have not been completed in order to explore the relationships between the stage of planning control of CDAs and particular variables.
Through quantitative statistical analyses, this paper confirms that the stage of planning control does not cause a delay in the development process of the completed CDA sites. Approval rate of planning applications does not necessarily affect the development process of them. Instead, the relatively lengthy amount of time spent in the development process in the completed CDA sites can be stemmed from the change of mind of the planning applications’ applicants. The GFA of completed CDA sites affects the length of time spent in the development process. In addition, when the year of the first approved planning application of completed CDA sites is closer to year 2014, the length of time spent in the whole development process is less. For the 67 approved applications submitted for the uncompleted CDA sites, it is confirmed that the GFA of the proposed developments cause impacts on the length of time a planning application involved to get an approved decision from the planning authority.
Based on the findings collected, it is concluded that the stage of planning control does not cause a delay in the completed CDA sites and, various factors play a part accounting for the length of time spent in the development process and in getting approved decisions from the planning authority.published_or_final_version
Urban Planning and Design
Master
Master of Science in Urban Planning
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Saulosse, Pedro Ausêncio Bonifácio. "A utilização do SROI como indicador de impacto social : estudo de caso do PFC-CDA (Moçambique)". Master's thesis, Instituto Superior de Economia e Gestão, 2020. http://hdl.handle.net/10400.5/20814.
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Mestrado em Contabilidade, Fiscalidade e Finanças EmpresariaisEsta dissertação visa construir uma estrutura para medir os benefícios sociais, económicos e ambientais das atividades da Câmara dos Despachantes Aduaneiros de Moçambique (CDA) para o Despachante Aduaneiro (DA). A estrutura é baseada na abordagem preditiva do retorno social do investimento (SROI). As evidências foram coletadas a partir de dados quantitativos e qualitativos, entrevistas, questionários e revisão da literatura. Com o envolvimento dos stakeholders, a análise examinou os impactos de curto, médio e longo prazos e atribuiu valores aos impactos sociais usando proxies financeiras. Esta dissertação contribui para uma compreensão da criação do valor social no contexto das associações de profissionais e apresenta um modelo lógico para auxiliar o DA na tomada de decisão sobre que projetos a CDA deve ou não implementar.
This dissertation aims to build a structure to measure the social, economic and environmental benefits of the activities of the Chamber of Customs Brokers of Mozambique (CDA) for the Custom Broker. The structure is based on the social return on investment (SROI) predictive approach. Evidence was collected from quantitative and qualitative data, interviews, questionnaires and literature review. With stakeholder involvement, the analysis examined impacts in the short, medium and long terms and assigned values to social impacts using financials proxies. This dissertation contributes to an understanding of social value creation in the context of professional associations and presents a logic model to assist the Custom Broker in decisions making about which projects the CDA should or not implement.
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Kahrobaee, Nina y Pezo Stefanie Rumaina. ""Someone isn't telling the truth" : En kritisk diskursanalys av den amerikanska dagspressens nyhetsbevakning av sexuella trakasserier". Thesis, Högskolan för lärande och kommunikation, Högskolan i Jönköping, HLK, Medie- och kommunikationsvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-43009.
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Den här studien analyserar hur maktstrukturer framträder i den amerikanska dagspressens bevakning av sexuella trakasserier. Studien analyserar 18 artiklar som har bevakat två snarlika fall där två män som varit nominerade till en position i Högsta domstolen i USA blivit anklagade för sexuella trakasserier. Det första fallet från 1991 är mellan Clarence Thomas och Anita Hill och det senare fallet är från 2018 mellan Brett Kavanaugh och Christine Blasey Ford. Artiklar från Wall Street Journal, New York Times och Chicago Tribune, som är de tre ledande dagstidningarna i USA har studerats med syfte att avslöja om det finns några underliggande ideologier och maktintressen i texten. För att avslöja dessa konstruktioner utgår studien från en kritisk diskursanalys som metod med målet att kunna se hur de språkliga resurserna uttrycker ideologier och maktintressen. Studiens teoretiska ramverk har främst utgått från genusteori, och därefter utifrån hegemoni, rape culture, nyhetsjournalistik och tabloidisering. Med hjälp av olika analysverktyg har sammanlagt 18 artiklar analyserats där materialet har delats in i fyra teman, och utifrån dem har texterna analyserats mer utförligt. Resultatet visar att patriarkala maktstrukturer uttrycker sig i olika grad i artiklarna och att det har skett en förändring i den journalistiska diskursen över tid.This study analyzes how power structures express themselves in the daily press's coverage of sexual harassment. The study analyzes 18 articles that have covered two similar cases where two men who have been nominated for a position in the Supreme Court in the United States have been accused of sexual harassment. The first case from 1991 is between Clarence Thomas and Anita Hill and the latter case is from 2018 between Brett Kavanaugh and Christine Blasey Ford. Articles from the Wall Street Journal, New York Times and the Chicago Tribune, which are the three leading newspapers in the United States, have been analyzed with the aim of revealing whether there are any underlying ideologies and power interests in the text. In order to uncover these constructs, the study uses CDA as a method for being able to see how the linguistic resources express ideologies and power interests. The study’s theoretical framework has mainly been based on gender theory, and then based on hegemony, rape culture, news journalism and tabloidization. With the help of various analysis tools, a total of 18 articles have been analyzed where the material has been divided into four themes, and based on them the texts have been analyzed in more detail. The result shows that patriarchal power structures express themselves to varying degrees in the articles and that there has been a change in journalistic discourse over time.
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Ekici, Denis Kendal. "Imagination : the making of Kurdish national identity in the Kurdish journalistic discourse (1898-1914)". Thesis, University of Exeter, 2015. http://hdl.handle.net/10871/16882.
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By utilizing Critical Discourse Analysis (CDA) methodology, this study explores the ideological function of language in the Kurdish journalistic discourse of the pre-WWI period (1898-1914). Informed by the CDA approach, the present study perceives language as a social practice that produces meanings and presumes a dialectical relationship between language and ideology in the construction of social realities, beliefs and identities. Hence, this study is situated within the wider scope of discourse analysis that focuses on the link between identity, discourse, power and ideology. The study particularly utilizes, in an eclectic manner, the CDA conceptual frameworks developed by Norman Fairclough and Ruth Wodak in order to examine and explain the ideological function of the Kurdish journalistic discourse in the formation of Kurdish national identity from the prespective of a linguistically informed discursive study. To this end, from the perspective of CDA approach, the study methodically and analytically conducts an exhaustive close textual examination of numerous discourse samples taken from the corpora of three Kurdish journals of the late Ottoman period, i.e., Kurdistan (1898-1902), Kürd Teavün ve Terakki Gazetesi (The Kurdish Gazette for Mutual Aid and Progress) (1908-1909) and Rojî Kurd (Kurdish Sun) (1913). Given that the historical circumstance have a tremendous effect on the formation of discourses, this study investigates discourse practices and language devices employed in the Kurdish journals by taking into consideration the distinctive sociocultural and political conditions in which each journal was published. The study concludes that contrary to the common misperception in the literature, the Kurdish press of the late Ottoman period served as a platform on which Kurdish intellectuals negotiated, constructed and disseminated a distinctive form of Kurdish national identity and nationalism in their discourse despite –sometimes at the expense of- the hegemonic Ottoman and Pan-Islamic identities. However, although the Kurdish journalistic discourse managed to produce a Kurdish nationalist discourse among the Kurdish intellectuals and a small segment of Kurdish reading public, it failed to imitate the Andersonian notion of ‘imagined communities’ as the ‘cultural products’ of ‘print-capitalism’ that would immensely contributed to the formation of a unified field of communication around a national print-language. As a result the Kurdish identity discourse remained inconsequential in terms of making an impact among a larger Kurdish public that would ultimately lead to the construction of a braoder imagined Kurdish national community. The present study attributes the limited power and influence of the Kurdish journals or the Kurdish printing-press on Kurdish masses to the unfavourable historical circumstances, including the novelty of the newspaper genre, the low literacy rate in Kurdistan, the state-imposed restrictions on the production and dissemination of the journals, the personal and familial concerns and interests of the Kurdish leadership of the period and the lingering effects of both parochial (tribal, linguistic, sectarian, regional) and meta-loyalties (Islamism, Ottomanism) among Kurds in the era of nationalism.
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Kokalari, Ina y Gabriela Carlehed. "En analys av PR´s inblandning i journalistiken". Thesis, Stockholms universitet, Institutionen för mediestudier, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-87468.
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Detta är en uppsats i media - och kommunikationsvetenskap som tar upp PR´s inflytande i journalistiken med hjälp av två olika metoder. Först har vi gjort en kvantitativ innehållsanalys där vi jämfört förekomsten av utvalda PR-begrepp från två olika år med tjugo och arton års intervall, 1992 och 1995, samt 2012. Detta för att få fram om det skett en förändring i journalisters användande av begreppen. Därefter följer en kritisk diskursanalys där vi analyserar två nyhetstexter för att med hjälp av van Dijks CDA-modell få fram sociologiska, kulturella och hierarkiska strukturer i texterna. Detta gjordes i syfte att genom dekonstruktion av texterna få fram om en PR-isering har skett i form av journalisters språkbruk och med hjälp av lingvistiska verktyg få fram dolda budskap. Våra frågeställningar lyder som följer: Hur frekvent och i vilken omfattning förekommer utvalda PR-begrepp i dagstidningarna Dagens Nyheter och Svenska Dagbladet 2012 jämfört med för 20 år sedan? (Kvantitativ) Vi vill belysa på vilket sätt PR förekommer i nyhetsmedierna med tanke på PR´s förändrade roll idag, och på vilket sätt man kan se detta i journalistiken? (CDA-analys) Hur kan man, med hjälp av textanalys, urskilja och förstå PR´s inblandning i journalistiska nyhetsartiklar? (CDA-analys) Syftet är att få fram om en PR-isering kan urskiljas i nyhetsartiklar och hur den PR-iseringen ser ut. Detta har vi kunnat göra genom att använda oss av ett flertal teoretiska ramverk som bland annat diskuterar PR som en påverkande aktör, journalistikens objektivitetsideal och institutionaliseringen. Habermas teorier i diskussionen om demokrati tas upp och även hur olika ”habitualiseringar” legitimerar sociala konstruktioner. Trovärdighetsaspekter diskuteras ur ett moralfilosofiskt perspektiv där även en postmodernistisk teoriram kompletterar en djupgående kritisk vinkel på hur texter genomsyras av manipulationer. En övergripande samhällssyn finns hos sociologen Giddens diskussioner om förändringar i samhället som påverkar PR och journalistiken. Genom dessa teoretiska ramverk och de två analyser som vi har genomfört kan vi åskådliggöra en PR-isering, då resultaten visar hur en branschs språkbruk influerar och anammas av en annan, i detta fall journalistiken. Vi har belyst PR-iseringens mängd i nyhetsartiklar genom att kartlägga hur frekvent och i vilken omfattning förekomsten av utvalda PR-begrepp är i dagstidningarna Dagens Nyheter och Svenska Dagbladet år 2012 jämfört med 20 år tillbaka. Vi har i denna uppsats även kunnat se hur valda artiklar är inbäddade i olika situationer, institutioner och osynliga strukturer i samhället. Vi vill med denna uppsats berika forskningen inom integrationen mellan PR och journalistik.
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Wennerholm, Matilda. "Krisen i Ukraina : En kritisk diskursanalys av nyhetsrapporteringen iThe New York Times och Dagens Nyheter". Thesis, Stockholms universitet, Institutionen för mediestudier, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-104193.
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Syftet med denna studie har varit att undersöka och jämföra hur den politiska krisen iUkraina återspeglats i Dagens Nyheter (Sverige) och The New York Times (USA).Frågorna som besvaras är hur rapporteringen i artiklarna under en utvald vecka iutvecklingen ser ut, utifrån teorier om gestaltning, personifiering och narrativ. Det görssamtidigt en jämförelse mellan de olika tidningarna för att skilja ut likheter eller skillnader ideras rapportering, samt för att undersöka om ländernas nationella intressen syns i texterna.Underlaget för studien är publicerat i de valda tidningarna under en specifik vecka ifebruari. Materialet består av totalt fjorton artiklar, sju ifrån varje tidning från varje dag iveckan. Med en kritisk diskursanalys enligt van Dijks modell har sedan en analys avsamtliga artiklar genomförts. Resultatet av analysen har visat att rapporteringen i bådatidningarna har beskrivit konflikten som en politisk sådan. Fokus i texterna har legat på attframhäva relationer mellan olika politiska aktörer samt mellan de inblandade nationerna.Politiken har framställts som spelgestaltad i båda tidningarna, då de beskrivit den politiskautvecklingen som strategi och spel. Det har även funnits tydliga indikationer påkrigsjournalistik i texterna. Var det gäller nationella intressen har de kunnat upptäckasgenom en analys av personifiering av politiska aktörer i texterna. Aktörer i artiklarna harrepresenterat olika nationers eller unioners politiska intressen i Ukraina.
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Axäll, Lena. "Jämställdhet kontra valfrihet : En kritisk diskursanalys av debatten om kvoterad föräldraförsäkring". Thesis, Stockholms universitet, Sociologiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-87706.
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Denna studie är en kritisk diskursanalys av den debatt som pågår i svensk dagspress om förslaget att införa en mer eller helt kvoterad föräldraförsäkring. Jag har främst fokuserat på hur orden ”jämställdhet” kontra ”valfrihet” konstrueras och ges mening i debatten samt vilka konsekvenser detta får. Studien bygger på ett socialkonstruktionistiskt antagande som ligger till grund för hur det skrivna språket konstrueras och skapar mening hos människor. Som metod har jag använt mig av kritisk diskursanalys där jag utgått från Faircloughts tredimensionella modell vid tolkandet av materialet. Mina data har bestått av 30 tidningsartiklar, utkomna under det senaste året, som på något sätt berört mitt ämne. I studiens resultat framkommer att orden ”jämställdhet” och ”valfrihet” används flitigt i debatten men ges olika innebörd beroende på i vilken kontext de används. Jämställdhetsargumentet utesluter i princip alltid valfrihetsargumentet men omvänt kan de två ståndpunkterna ofta förenas. Debatten ger upphov till att klassiska könsroller reproduceras snarare än omkonstrueras.
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Marufu, Mufudzi Anesu Chapman. "Robust and cheating-resilient power auctioning on Resource Constrained Smart Micro-Grids". Thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28414.
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The principle of Continuous Double Auctioning (CDA) is known to provide an efficient way of matching supply and demand among distributed selfish participants with limited information. However, the literature indicates that the classic CDA algorithms developed for grid-like applications are centralised and insensitive to the processing resources capacity, which poses a hindrance for their application on resource constrained, smart micro-grids (RCSMG). A RCSMG loosely describes a micro-grid with distributed generators and demand controlled by selfish participants with limited information, power storage capacity and low literacy, communicate over an unreliable infrastructure burdened by limited bandwidth and low computational power of devices. In this thesis, we design and evaluate a CDA algorithm for power allocation in a RCSMG. Specifically, we offer the following contributions towards power auctioning on RCSMGs. First, we extend the original CDA scheme to enable decentralised auctioning. We do this by integrating a token-based, mutual-exclusion (MUTEX) distributive primitive, that ensures the CDA operates at a reasonably efficient time and message complexity of O(N) and O(logN) respectively, per critical section invocation (auction market execution). Our CDA algorithm scales better and avoids the single point of failure problem associated with centralised CDAs (which could be used to adversarially provoke a break-down of the grid marketing mechanism). In addition, the decentralised approach in our algorithm can help eliminate privacy and security concerns associated with centralised CDAs. Second, to handle CDA performance issues due to malfunctioning devices on an unreliable network (such as a lossy network), we extend our proposed CDA scheme to ensure robustness to failure. Using node redundancy, we modify the MUTEX protocol supporting our CDA algorithm to handle fail-stop and some Byzantine type faults of sites. This yields a time complexity of O(N), where N is number of cluster-head nodes; and message complexity of O((logN)+W) time, where W is the number of check-pointing messages. These results indicate that it is possible to add fault tolerance to a decentralised CDA, which guarantees continued participation in the auction while retaining reasonable performance overheads. In addition, we propose a decentralised consumption scheduling scheme that complements the auctioning scheme in guaranteeing successful power allocation within the RCSMG. Third, since grid participants are self-interested we must consider the issue of power theft that is provoked when participants cheat. We propose threat models centred on cheating attacks aimed at foiling the extended CDA scheme. More specifically, we focus on the Victim Strategy Downgrade; Collusion by Dynamic Strategy Change, Profiling with Market Prediction; and Strategy Manipulation cheating attacks, which are carried out by internal adversaries (auction participants). Internal adversaries are participants who want to get more benefits but have no interest in provoking a breakdown of the grid. However, their behaviour is dangerous because it could result in a breakdown of the grid. Fourth, to mitigate these cheating attacks, we propose an exception handling (EH) scheme, where sentinel agents use allocative efficiency and message overheads to detect and mitigate cheating forms. Sentinel agents are tasked to monitor trading agents to detect cheating and reprimand the misbehaving participant. Overall, message complexity expected in light demand is O(nLogN). The detection and resolution algorithm is expected to run in linear time complexity O(M). Overall, the main aim of our study is achieved by designing a resilient and cheating-free CDA algorithm that is scalable and performs well on resource constrained micro-grids. With the growing popularity of the CDA and its resource allocation applications, specifically to low resourced micro-grids, this thesis highlights further avenues for future research. First, we intend to extend the decentralised CDA algorithm to allow for participants’ mobile phones to connect (reconnect) at different shared smart meters. Such mobility should guarantee the desired CDA properties, the reliability and adequate security. Secondly, we seek to develop a simulation of the decentralised CDA based on the formal proofs presented in this thesis. Such a simulation platform can be used for future studies that involve decentralised CDAs. Third, we seek to find an optimal and efficient way in which the decentralised CDA and the scheduling algorithm can be integrated and deployed in a low resourced, smart micro-grid. Such an integration is important for system developers interested in exploiting the benefits of the two schemes while maintaining system efficiency. Forth, we aim to improve on the cheating detection and mitigation mechanism by developing an intrusion tolerance protocol. Such a scheme will allow continued auctioning in the presence of cheating attacks while incurring low performance overheads for applicability in a RCSMG.
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Nauta, Melanie. "Walt Disney’s Moana, “We are Polynesia” : A CDA of Disney’s representation of the Polynesian culture inside Moana". Thesis, Högskolan för lärande och kommunikation, Högskolan i Jönköping, HLK, Medie- och kommunikationsvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-40639.
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Disney is known for their family animation movies with a non-western or indigenous cultural background. Nevertheless, Disney is basically very influential for the perception of cultures by a global audience. Many studies have proven that Disney’s depiction of a certain represented culture has not always been that clean. Of course two side notes are that Disney does make movies from an American dominant perspective and second, there is no such thing as a ‘real’ or ‘correct’ culture. Now, with the movie Moana freshly released in 2016, Disney took a step in the indigenous Polynesian culture. This research uses a thorough Critical Discourse Analysis to analyse how Disney portrays Polynesia and the Polynesian culture inside four selected samples of the movie Moana. This analysis is combined with the theories and concepts of Americanisation, Disneyfication and cultural appropriation to find out mixtures of the portrayed Polynesian culture with American and Disney values. Interesting findings were that Disney indeed portrays a hotchpotch of many cultures that can be found in Polynesia. Disney took care of highlighting the culture in the general storyline, in the characters and in the small details. Disney uses details of Polynesian mythology and the history around the ancient voyagers and wayfinding techniques for the storyline. What Disney emphasises is the importance of family, their history and their culture. Disney always portrays the culture with a certain emission of power and pride. However, the American dominancy is still noticeable. For example, the depiction of the coconut and the plumeria flower are signs of Americanised Polynesia. The American and Disney values are all visible during the whole movie and can be found in quotes, gestures and behaviour of characters as Moana, the ocean and demigod Maui. Especially Maui is being portrayed as the ‘American dominant hero’ even though Maui is considered to be a honoured and popular Polynesian demigod.
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Olofsson, Lina. ""Hela inlandet ligger ju i medieskugga" : Vilhelminabors upplevelser av lokaljournalistik". Thesis, Umeå universitet, Institutionen för kultur- och medievetenskaper, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-101370.
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In the light of the problems the media industry are struggling with, local news reporting is only one of the challenges the news organizations are facing. When local editors is being moved to the cities the tie with the local community is being severed. The aim of this study has been to analyze how the inhabitants of Vilhelmina municipality talks about their experiences of local journalism. With methodological inspiration from the Critical discourse analysis (CDA) this study examined the discourses of local journalism, social media, journalism's role and municipal policy. The theorectical framework consisted theories of media and democracy, convergence culture and discourse theory. The survey was conducted with four focus groups interviews. The focus groups were divided in different cathegories based on the participants experiences, ages and employment. The groups consisted of politicians, senior citizens, municipal employees and younger students. Results showed that some of the groups put high value in physical presence and that the absence of local editors were seen as a problem. The importance of local journalism were unmistakable and the groups talked about local journalism in similar ways. Different opinions mostly occured when it came to discourses about the importance and effects of social media. Another discourse that were identified were the discourse about the political climate in Vilhelmina. The changing media landscape were seen as one of the main factors when it came to conflicts and misunderstandings that have characterized the debate in the last years. In summary, a changed media landscape can not only be seen as a threat. In fact, in small municipalities like Vilhelmina, technological developments might be one of the solutions when it comes to maintain local journalism. The biggest problem is rather the lack of investigative journalism that occur when local editors is disappearing.
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Silva, Gustavo de Souza e. "Novos instrumentos de financiamento do agronegócio brasileiro e uma análise das alternativas de investimentos para o CDA/WA". Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/11/11132/tde-21062006-104414/.
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O instrumento tradicional de financiamento é aquele utilizado pelo Sistema Nacional de Crédito Rural - SNCR e que possui como fonte o orçamento do governo, as exigibilidades bancárias, a poupança verde etc. Os instrumentos não tradicionais podem ser considerados os novos mecanismos com fonte de recursos privados e que pretendem substituir os instrumentos tradicionais no financiamento agropecuário. A Lei n° 11.076, de 30 de dezembro de 2004, oficializou cinco títulos de créditos que deverão ser utilizados pelos agentes do agronegócio para captarem recursos privados para o seu financiamento e aumentar o giro de capital dentro do próprio setor, além de dar nova redação à Lei n° 9.973, de 29 de maio de 2000, que dispõe sobre o sistema de armazenagem dos produtos agropecuários. Os novos instrumentos de financiamento do agronegócio são denominados de: Certificado de Depósito Agropecuário - CDA, Warrant Agropecuário - WA, Certificados de Direitos Creditórios do Agronegócio - CDCA, Letra de Crédito do Agronegócio - LCA e Certificado de Recebíveis do Agronegócio - CRA. O objetivo destes instrumentos é desvincular a concessão de crédito do sistema oficial e desenvolver um novo mecanismo de financiamento do agronegócio através de papéis lastreados em produtos depositados e títulos de dívidas agrícolas que deve ampliar o relacionamento entre o setor financeiro e o setor como um todo, devendo tornar o financiamento mais eficiente para o produtor e menos onerosos aos cofres públicos. Este trabalho define o cenário brasileiro onde estes novos títulos do agronegócio foram instituídos, apresenta as justificativas para a criação destes títulos e expõe os mecanismos atualmente utilizados pelo mercado para captar recursos da iniciativa privada, apresenta e discute a legislação desses novos instrumentos. E por último buscaram-se alternativas de investimento para estes papéis nos mercados físicos e futuros de seis produtos agrícolas de janeiro de 2005 a outubro de 2005: açúcar cristal, algodão, arroz, café arábica, milho e soja. Duas situações foram consideradas: especulações com o CDA e o WA, onde o investidor adquire o papel e especula com cada produto; e operação de spread, onde o investidor compra o CDA/WA (mercado físico) e trava o rendimento numa operação com o mercado futuro da Bolsa de Mercadorias & Futuros - BM&F, sem ficar exposto a variações de preço. No caso do arroz apenas a análise dos preços físicos foi elaborada devido à ausência do mercado futuro para este produto na BM&F. A partir disso, concluiu-se que a especulação com os produtos agrícolas não teve um bom resultado no período. Já as operações de spread do mercado futuro da BM&F com o CDA/WA ofereceram boas oportunidades de rentabilidade ao investidor que conseguiu captar o momento correto para a operação.The traditional instrument of financing is that one used by the National System of Rural Credit - SNCR and that has as source of resource the budget of the government, the banking liabilities, the green saving. The not traditional instruments can be considered the new mechanisms which have as source of funding private resources and that aims as to substitute the traditional instruments of the farming financing. The Law 11,076, of December 30, 2004, officialized five titles of credits that will have to be used by the agents of the agribusiness to raise private resources to its financing and to increase the turn of capital of the own sector, besides giving new writing to the Law number 9,973, of May 29, 2000, which deliberates on the system of storage of the farming products. The new instruments of financing of the agribusiness are: Certificate of Agribusiness Deposit - CDA, Agribusiness Warrant - WA, and Certificates of Rights to Receive - CDCA, Agribusiness Letter of Credit - LCA and Certified of Receivable of the Agribusiness - CRA. The objective of these instruments is to detach the concession of credit of the official system and to develop a new mechanism of financing of the agribusiness through titles based in deposited agricultural products and titles of agricultural debts that must increase the relationship between the financial and agribusiness sector as a whole, and it is expected that the financing will become more efficient for the producer and less expensive to the government. This work defines the Brazilian scene where these new titles have been created, it presents the justifications for the creation of these titles and shows the mechanisms used by the market to raise resources from the private sector, presents and it discuss the legislation of these new titles. Finally, it was searched alternative of investment for these papers in the physical and future markets of six agricultural products using data from January 2005 to October of 2005: bulk sugar, cotton, rice, Arabica coffee, maize and soybean. Two situations had been considered: speculations with the CDA and WA, where the investor acquires the title and speculates with each product; and operation of spread, where the investing purchase the CDA/WA (physical market) and locks the interest rate in an operation with the futures market of the Brazilian Mercantile & Futures Exchange - BM&F, without being exposed to the price variations. In the case of the rice only the analysis of the physical prices was done because of the absence of the futures market for this product in the BM&F. From this, it was concluded that the speculation with the agricultural products did not have good results in the period. However, the operations of spread of the futures market of the BM&F with the CDA/WA had offered good opportunities of profitability to the investor who was able to operate at the correct moment.
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Arsofli, Diala. "From Heroes to Helpless Refugees: A CDA of The Representation of North Korean Refugees in South Korean Law". Thesis, Malmö universitet, Fakulteten för kultur och samhälle (KS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-23717.
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The dictator ruled North Korea is not a country many North Koreans chose to live in voluntarily. Thousands of North Koreans must endure starvation, public executions, prison camps, rape, and numerous other human rights abuses daily. As a result, many choose to flee the country, hoping for a better and safer life in South Korea. This paper investigates how North Korean refugees are represented in the current North Korean Refugees Protection and Settlement Support Act and its Enforcement Decree Act. This study aims to examine the changes made to the Acts that are relevant to the representation of North Korean refugees in South Korea. I examine the Acts with Critical Discourse Analysis and Fairclough’s Three-dimensional Model of Discourse. The results suggest that the Acts contribute to the negative perception of North Korean refugees by some South Korean nationals. Unstable inter-Korean relations enhance these negative attitudes.
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Botolfsson, Sara y Anna-Karin Cornvik. "Talet om invandrarkvinnan i svensk dagspress". Thesis, Stockholm University, Department of Social Work, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7010.
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Medias makt att påverka individers sätt att tolka verkligheten är stor. Alltså blir betydelsen för hur man väljer att skriva någonting viktigt då det påverkar den sociala praktiken, i fråga om makt, inflytande för individer och grupper. Vi har i denna uppsats lagt fokus på svensk nyhetsmedias framställning av invandrarkvinnan. Vårt syfte med uppsatsen var att undersöka och analysera diskursen kring invandrarkvinnan i svensk dags- samt kvällspress utifrån frågeställningarna; Hur skildras den invandrade kvinnan i svensk dags- samt kvällspress? och Förekommer stereotyper kring invandrarkvinnan och i så fall hur ser de ut? Det finns ingen tidigare forskning med samma syfte, dock förekommer det forskning kring hur media skildrar invandrare och flyktingar. Den tidigare forskningen pekar på medias roll i skapandet av De Andra i syfte att skapa en svensk identitet.
Vi har genomfört en kritisk diskursanalys med utgångspunkt i Faircloughs Critical Discourse Analysis. Uppsatsens teoretiska utgångspunkter har varit socialkonstruktivism och genusteori. Empirin är baserad på 63 artiklar hämtade från Svenska Dagbladet, Dagens Nyheter, Expressen och Aftonbladet, publicerade under åren 2005 och 2006. De fyra teman som var tydliga i artikelmaterialet är: konstruktionen av de andra, heder, religion & kultur samt integration. Våra resultat visar på ett likartat skildrande av den invandrade kvinnan som ett offer för olika strukturer. Dels för samhälliga strukturer samt för kulturella och religiösa strukturer. Vårt artikelmaterial påvisar även en motdiskurs, om än en svag sådan, i vilken invandrarkvinnans etniska och kulturella bakgrund framställs som någonting positivt.
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Torstensson, Emelie. "My Europe does not build walls : The Swedish government´s discourse change in the refugee issue". Thesis, Högskolan för lärande och kommunikation, Högskolan i Jönköping, HLK, Medie- och kommunikationsvetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-31559.
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Eriksson, Rebecca. ""Man måste alltid få prata om allting som är sant" : En diskursanalytisk studie av medborgarskap och legitimitet". Thesis, Umeå universitet, Institutionen för kultur- och medievetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125372.
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The purpose with this essay is to, through societal discussion via different media, analyze how citizenship and legitimacy is constructed and negotiated through the discourses surrounding two vulnerable groups in the swedish society, the roma people and the syrian refugees. By analyzing different types of texts from two local newspapers and also from new media such as blogs and archived chats it is possible to see how certain groups are stigmatized and objects of discrimination. The material in the analyze is coded by which type of text it belongs to but it is also categorized by how official the pespective of the writer is, and it is argued that the role of the traditional media still is very important in terms of educating the public about issues and groups in society which they would likely meet and interact with themselves. The analysis also focus on which geographical perspective the writer has since this could show if an issue, theme or discourse is contextualized with bigger issues and globalization. The theoretical and methodical frame work of this analyze is critical discourse analysis with the focus on discursive construction of national identity by Wodak. Theories about citizenship and legitimacy according to Lister also applies to the study. Keywords: Discourse analysis, CDA, citizenship, legitimacy, roma, syria, migrants, refugees
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Olsson, Sanna y Ebba Wiksholm. ""Vi är rika och unga och har det jävligt jävligt najs" : En kritisk diskursanalys av reality-programmet Ung och bortskämd". Thesis, Högskolan för lärande och kommunikation, Högskolan i Jönköping, HLK, Medie- och kommunikationsvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-34977.
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Öberg, Rickard. "Varthän flyr vi, mina tappra män? : En komparativ studie av militärideologi i Vegetius och Ammianus Marcellinus texter". Thesis, Stockholms universitet, Historiska institutionen, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-156956.
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This study is situated between the disciplines of military history and the history of ideas. It focuses on two late Roman writers; the bureaucrat Vegetius and the historian Ammianus Marcellinus. Drawing on linguistic methodology and a theory of ideology formulated by the Swedish political scientist Herbert Tingsten, this is the first comprehensive and comparative study of these two important sources of information on the late Roman military. The purpose of the study has been to elucidate and explain ideological differences and similarities between the two figures. Previous research suggests that Vegetius’ De Re Militari is a less trustworthy source given its author’s lack of military experience and his reliance on earlier written sources. By comparing it with Ammianus’ Res Gestae, a source often attributed greater credibility, this study hoped to demonstrate significant similarities that would warrant a re-evaluation of Vegetius’ source value. However, the conclusion drawn from the comparative examination of these two texts is that Ammianus and Vegetius did not share a common military ideology and that there are no grounds for a profound re-evaluation of Vegetius’ credibility.
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Maschinez, Swetlana. "Ideological Representation of the U.S. Presidential Candidates in the Editorial Positions of the English Online Newspapers in Russia - A Critical Discourse Analysis". Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1515433218122878.
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Pinheiro, CatiÃssia Dantas. "CÃlulas CD3+, CD4+, CD8+, CD3-CD16+CD56+ e CD19+ em sangue perifÃrico de pacientes com hansenÃase e indivÃduos saudÃveis". Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=16323.
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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgicoA hansenÃase à uma doenÃa granulomatosa, infecto-contagiosa causada pelo Mycobacterium leprae. Trata-se de uma infecÃÃo crÃnica com amplo espectro de respostas imunes celulares em humanos. Possui alto poder infectante e baixo poder patogÃnico. Este estudo tem como objetivo quantificar e comparar leucÃcitos e subpopulaÃÃes de linfÃcitos T totais (CD3+), T auxiliares (CD3+CD4+), T citotÃxicos (CD3+CD8+), B (CD19+) e NK (CD3-CD16+CD56+) em sangue perifÃrico de indivÃduos com hansenÃase e controles saudÃveis. Os pacientes foram provenientes do Centro de Dermatologia D. LibÃnia, Fortaleza-CE, Brasil. A determinaÃÃo do nÃmero de linfÃcitos em cada subpopulaÃÃo foi realizada por citometria de fluxo. A anÃlise estatÃstica foi realizada pelo programa GraphPad Prism 5.0 para Windows com significÃncia estabelecida para valores de p<0,05. à um estudo do tipo caso controle de carÃter observacional, realizado a partir da anÃlise do sangue perifÃrico de indivÃduos com diagnÃstico de hansenÃase e de indivÃduos saudÃveis. A populaÃÃo de pacientes com hansenÃase, sem tratamento foi composta de 15 pessoas. A populaÃÃo de controles saudÃveis foi composta por 29 pessoas. As mÃdias das contagens de LinfÃcitos NK (CD3-CD16+CD56+) no grupo de pacientes com hansenÃase e nos controles saudÃveis, dadas em cÃlulas/mm3, foram, 147(Â113,4) e 378,1 (Â231,7) respectivamente, p = 0,0008. As mÃdias das contagens de LinfÃcitos B (CD19+) no grupo de pacientes com hansenÃase e nos controles saudÃveis, dadas em cÃlulas/mm3, foram, 233,3 (Â85,89) e 115,3 (Â53,01) , respectivamente, p < 0,0001. NÃo foram encontradas diferenÃas estatÃsticas significantes entre as amostras de leucÃcitos, de linfÃcitos T CD3+, linfÃcitos T CD4+ e linfÃcitos T CD8+. Os dados do presente estudo sinalizam que as cÃlulas NK parecem desempenhar papel de relevÃncia na resposta ao M. leprae. O linfÃcito B jà ocupa papel de destaque na resposta imunolÃgica ao M. leprae, sobretudo nas formas lepromatosas, e este estudo reforÃa a importÃncia destas cÃlulas.
Leprosy is an infectious and granulomatous disease caused by Mycobacterium leprae. The aim of this study was to quantify and compare levels of leucocytes and lymphocyte subpopulations (CD3+, CD3+CD4+, CD3+CD8+, CD19+, CD3-CD16+CD56+) in peripheral blood of patients with leprosy and healthy controls. Patients were followed at Centro de Dermatologia D. LibÃnia, Fortaleza-CE, Brasil. Flow cytometry was used to determine numbers of lymphocytes. Statistical analisys was done with GraphPad Prism 5.0 software for windows. P values under 0.05 were considered siginificant.This was an observational case-control study. Fifteen leprosy patients without treatment were evaluated and 29 healthy individuals were included in control group. NK cells (CD3-CD16+CD56+) mean in leprosy patients was 147(Â113,4) and in controls was 378,1 (Â231,7). Comparisson stablished a p value of 0.0008. B lymphocytes (CD19+) mean in leprosy patients was 233,3 (Â85,89) and in controls was 115,3 (Â53,01), with p < 0,0001 . No differences were observed in CD3+ T lymphocytes, CD4+ T lymphocytes and CD8+ T lymphocytes. This study suggests that NK cells may play a role in innate response to M. leprae.
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Pinheiro, Catiússia Dantas. "Células CD3+, CD4+, CD8+, CD3-CD16+CD56+ e CD19+ em sangue periférico de pacientes com hanseníase e indivíduos saudáveis". reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/15425.
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PINHEIRO, Catiússia Dantas. Células CD3+, CD4+, CD8+, CD3-CD16+CD56+ e CD19+ em sangue periférico de pacientes com hanseníase e indivíduos saudáveis. 2013. 65 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2013.Submitted by denise santos (denise.santos@ufc.br) on 2016-03-09T13:41:07Z No. of bitstreams: 1 2013_dis_cdpinheiro.pdf: 775643 bytes, checksum: 2d4939ef2f883a155737695a2e7c759a (MD5)
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Leprosy is an infectious and granulomatous disease caused by Mycobacterium leprae. The aim of this study was to quantify and compare levels of leucocytes and lymphocyte subpopulations (CD3+, CD3+CD4+, CD3+CD8+, CD19+, CD3-CD16+CD56+) in peripheral blood of patients with leprosy and healthy controls. Patients were followed at Centro de Dermatologia D. Libânia, Fortaleza-CE, Brasil. Flow cytometry was used to determine numbers of lymphocytes. Statistical analisys was done with GraphPad Prism 5.0 software for windows. P values under 0.05 were considered siginificant.This was an observational case-control study. Fifteen leprosy patients without treatment were evaluated and 29 healthy individuals were included in control group. NK cells (CD3-CD16+CD56+) mean in leprosy patients was 147(±113,4) and in controls was 378,1 (±231,7). Comparisson stablished a p value of 0.0008. B lymphocytes (CD19+) mean in leprosy patients was 233,3 (±85,89) and in controls was 115,3 (±53,01), with p < 0,0001 . No differences were observed in CD3+ T lymphocytes, CD4+ T lymphocytes and CD8+ T lymphocytes. This study suggests that NK cells may play a role in innate response to M. leprae.
A hanseníase é uma doença granulomatosa, infecto-contagiosa causada pelo Mycobacterium leprae. Trata-se de uma infecção crônica com amplo espectro de respostas imunes celulares em humanos. Possui alto poder infectante e baixo poder patogênico. Este estudo tem como objetivo quantificar e comparar leucócitos e subpopulações de linfócitos T totais (CD3+), T auxiliares (CD3+CD4+), T citotóxicos (CD3+CD8+), B (CD19+) e NK (CD3-CD16+CD56+) em sangue periférico de indivíduos com hanseníase e controles saudáveis. Os pacientes foram provenientes do Centro de Dermatologia D. Libânia, Fortaleza-CE, Brasil. A determinação do número de linfócitos em cada subpopulação foi realizada por citometria de fluxo. A análise estatística foi realizada pelo programa GraphPad Prism 5.0 para Windows com significância estabelecida para valores de p<0,05. É um estudo do tipo caso controle de caráter observacional, realizado a partir da análise do sangue periférico de indivíduos com diagnóstico de hanseníase e de indivíduos saudáveis. A população de pacientes com hanseníase, sem tratamento foi composta de 15 pessoas. A população de controles saudáveis foi composta por 29 pessoas. As médias das contagens de Linfócitos NK (CD3-CD16+CD56+) no grupo de pacientes com hanseníase e nos controles saudáveis, dadas em células/mm3, foram, 147(±113,4) e 378,1 (±231,7) respectivamente, p = 0,0008. As médias das contagens de Linfócitos B (CD19+) no grupo de pacientes com hanseníase e nos controles saudáveis, dadas em células/mm3, foram, 233,3 (±85,89) e 115,3 (±53,01) , respectivamente, p < 0,0001. Não foram encontradas diferenças estatísticas significantes entre as amostras de leucócitos, de linfócitos T CD3+, linfócitos T CD4+ e linfócitos T CD8+. Os dados do presente estudo sinalizam que as células NK parecem desempenhar papel de relevância na resposta ao M. leprae. O linfócito B já ocupa papel de destaque na resposta imunológica ao M. leprae, sobretudo nas formas lepromatosas, e este estudo reforça a importância destas células.