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1

Carlini, Sophia Magdalena. "Adenylate kinase values in cerebrospinal fluid as a marker to predict neurological outcome in children with meningitis." Thesis, Cape Technikon, 1997. http://hdl.handle.net/20.500.11838/1456.

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Thesis (Master's Diploma(Technology (Medical Technology))-- Cape Technikon, 1997<br>Meningitis in children is a common and serious disease. Bacterial and tuberculous meningitis often lead to neurological complications. A sensitive marker to predict brain damage in children with meningitis could be of great importance. Frithz F et aI, 1982 suggested that increased adenylate kinase values could indeed be used as a marker for brain damage. Adenylate kinase (AK) is an enzyme present in brain tissue. Low concentrations are present in normal cerebrospinal fluid (CSF) « 1 uti). Increased concentrat
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2

Ryder, Stephen J. "Studies on the recruitment of macrophages into the central nervous system." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309144.

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3

Tager, Dany, Anne Hatch, Jennifer Segar, Brentin Roller, Mohajer Mayar Al, and Tirdad T. Zangeneh. "Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia." ELSEVIER SCIENCE BV, 2017. http://hdl.handle.net/10150/625216.

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Central Nervous System (CNS) vasculitis is the most common life-threatening complication of coccidioidal meningitis. It is manifested by cerebral ischemia, hemorrhage, and infarction. We report a case of CNS vasculitis in a patient receiving chemotherapy and review of the literature on coccidioidal meningitis. The patient was treated with combination antifungal therapy and a short course of high dose corticosteroids with a modest improvement in her neurological examination after initiation of steroids.
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4

Stanley, Alan Michael. "The utility of CSF PCR in central nervous system Varicella zoster infection in HIV." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16778.

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Includes bibliographical references<br>Aims: To assess the clinical and cerebrospinal fluid characteristics, and the role of tuberculous meningitis (TBM) as a confounder, in a cohort of HIV positive individuals with positive varicella zoster virus (VZV) positive cerebrospinal fluid PCR. Methods: Patients in the NHLS database at Groote Schuur Hospital with positive CSF VZV PCR who were also HIV co-infected and whose folders were available for clinical review were reviewed. Clinical and biochemical data were collected. Patients were divided into two groups based an accepted case definition for T
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5

Abdalla, Hana Khidir. "Modulation of inflammatory mediators during experimental bacterial meningitis /." Linköping : Department of Molecular and Clinical Medicine, Linköping university, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med907s.pdf.

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6

Pelegrín, Senent Iván. "Clinical approach and management of bacterial infections of the central nervous system related to hydrocephalus." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/585886.

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INTRODUCTION: Community-acquired bacterial meningitis is a relevant entity related to a high morbidity and mortality, despite of the adjuvant and antibiotic treatments available. Morbidity and mortality are caused by neurological complications, being hydrocephalus one of the less investigated one and related to Listeria monocytogenes meningoencephalitis episodes, which increase have been reported in the last decade. Moreover, the devices used for treatment of hydrocephalus have a high risk of infection. These infections have a high personal and economic costs, and their prevention and treatme
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7

Saba, Villarroel Paola Mariela. "Epidemiology of central nervous system infections and of Zika virus in Bolivia." Thesis, Aix-Marseille, 2020. http://theses.univ-amu.fr.lama.univ-amu.fr/200424_SABAVILLARROEL_796lerwvy638nrfmjn965osdp469z_TH.pdf.

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Nous avons réalisé une étude prospective (nov-2017 à oct-2018) chez des patients boliviens hospitalisés suspectés d'infection du SNC pour identifier les plus courants étiologies et orienter les stratégies de diagnostic, de traitement, de prévention et de santé publique. Nous avons recruté 257 patients hospitalisés (20,2% VIH positifs), une étiologie infectieuse a été confirmée chez 49,8% des patients. Les principales étiologies chez les patients VIH positifs étaient Cryptococcus spp. (41,7%) et M. tuberculosis (27,8%) et chez les patients VIH négatifs, M. tuberculosis (26,1%) et S. pneumoniae
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8

Kihara, Michael. "Neurocognitive impairment following central nervous system infections in Kenyan children as detected by event related potentials." Thesis, Open University, 2008. http://oro.open.ac.uk/54642/.

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As mortality in childhood decreases due to advances in modern medicine, presence of better nutrition and fresh water supply, the impact of disability has become increasingly important especially in resource poor countries. Children living in sub- Saharan Africa are also exposed to a number of potentially debilitating infections which have been shown to have long-term cognitive effects even in absence of clinical neurological sequelae. The objective of the study is to demonstrate that event related potentials (ERPs) can be used to detect neurocognitive impairment following the most common centr
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9

Nunes, Rafaella Almeida Lima. "Aplicação de técnicas moleculares no diagnóstico laboratorial complementar das infecções virais do sistema nervoso central no Hospital Universitário da USP." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-19032014-160513/.

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Enterovírus (HEV), herpesvírus 1 e 2 (HHV-1 e HHV-2) e adenovírus (HAdV) são importantes agentes de infecções do SNC. Neste trabalho, técnicas moleculares foram aplicadas para a detecção destes vírus em quadros de infecção do SNC. Amostras de líquor foram colhidas de pacientes atendidos no HU-USP entre agosto e novembro/2010 e fevereiro/2012 a janeiro/2013. Através da Nested-PCR HEV foram detectados em 9,8% das amostras, HAdV em 2,5% e HHV-1 e 2 em 1,1%, além de 3 casos de coinfecção, 2 entre HEV e HHV, e 1 entre HEV e HAdV. O material genético viral foi extraído através dos métodos Qiaamp DNA
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10

Nunes, Cristina Freitas. "Etiologia das encefalites e meningites de líquor claro." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/99/99131/tde-27112018-144215/.

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Infecções no sistema nervoso central (SNC) causadas por microrganismos desencadeiam sintomas de moderados a severos, dependendo da região atingida, podendo ser designadas como encefalites ou meningites. Os vírus são os agentes mais comuns nestas infecções. Os agentes virais responsáveis por essas enfermidades que apresentam maior incidência na população mundial são certos herpesvírus, flavivírus, influenza A, enterovírus e vírus da caxumba. Entretanto, essa prevalência varia de acordo com a população, estado imunológico do indivíduo, idade e região estudada. Embora existam dados bem estabeleci
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11

Moragas, Garrido Mireia. "Infecciones del sistema nervioso central por Listeria monocytogenes." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/132629.

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Listeria monocytogenes (Lm) es un bacilo gram-positivo anaerobio facultativo con especial tropismo por el sistema nervioso central (SNC). La principal forma de afectación central en el adulto es la meningitis, siendo la rombencefalitis y el absceso cerebral más infrecuentes, pero de peor pronóstico. La forma de presentación de Lm es muy variable y a menudo se confunde con otras entidades más prevalentes creando una demora en el diagnóstico inicial y por lo tanto en su tratamiento. Las hipótesis de este trabajo se basan en que, los abscesos piógenos causados por Lm presentan determinadas
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12

Almeida, Milena Dorea de. "A criança com tumor de sistema nervoso central: considerações da psicanálise para a área da saúde." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/47/47133/tde-04062012-110150/.

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Este trabalho tem como objetivo investigar sentidos e significações que a criança com tumor de sistema nervoso central, que já passou pelo tratamento oncológico, tem da doença e das alterações corporais aparentes decorrentes do tumor e seu tratamento. Isso porque, em sua maioria, essas crianças apresentam sequelas visíveis no corpo ocasionadas pela doença e seu tratamento oncológico. Para a realização deste trabalho, recorre-se a uma pesquisa bibliográfica, na área da Oncologia Pediátrica, Psicologia e Psicanálise, e uma pesquisa de campo. Através de uma entrevista individual com onze crianças
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13

Hedström, Kajsa, and Ulrika Hillbom. "Tillväxt hos barn och ungdomar som behandlats med centralstimulatia : En journalgranskningsstudie." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-154710.

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Syfte: Att undersöka om det fanns något samband mellan behandling med centralstimulantia ochavvikande tillväxt hos barn och ungdomar med ADHD, samt att undersöka om eventuellt avvikandetillväxt hade något samband med ålder vid insättande, kön eller olika funktionshinder.Metod: 68 barn med ADHD som behandlats med centralstimulantia i minst två år inkluderades.Journalkopior inhämtades från Habiliteringen för barn och vuxna vid Uppsala läns landsting. Dessakopior innehöll barnens tillväxtkurvor, kön, diagnos och ålder. Kurvorna granskades med hjälp av enutformad granskningsmall. Barnens tillväxt
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14

Cheng, Ya-Chang, and 鄭雅靜. "Exploration of the correlation between children general anesthesia time and the central nervous system diseases." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/38302889658050205645.

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碩士<br>中國醫藥大學<br>醫務管理學系碩士班<br>100<br>Goals: Anesthesia is a complex pharmacological reaction. Whether general anesthesia will affect central nervous system in children is always the concern. The purpose of this study is to determine whether the duration of anesthesia have an impact on the certral nervous system at different age group of children under the database analysis from the National Health Insurance. Methods:Under "National Health Insurance Research Database of the year 2000, 1 million samples were collected. From 1997 to 2009,children who underwent anesthesia before the age of six was
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15

Domínguez, Punaro María de la Cruz. "Studies on the exaggerated inflammatory response caused by streptococcus suis at systemic and central nervous system levels." Thèse, 2010. http://hdl.handle.net/1866/4523.

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Streptococcus suis de type 2 est un microorganisme pathogène d’importance chez le porc. Il est la cause de différentes pathologies ayant comme caractéristique commune la méningite. C’est également un agent émergeant de zoonose : des cas cliniques humains ont récemment été rapportés en Asie. Cependant, la pathogénèse de S. suis n’est pas encore complètement élucidée. Jusqu’à présent, la réponse pro-inflammatoire initiée par S. suis n’a été étudiée qu’in vitro. L’étude du choc septique et de la méningite requiert toujours des modèles expérimentaux appropriés. Au cours de cette étude, nous avons
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16

Titman, Rebecca. "Saccadic eye movement tasks assess central nervous system dysfunction and cognitive improvements in children with fetal alcohol spectrum disorders." Thesis, 2010. http://hdl.handle.net/1974/5970.

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Background: The central nervous system (CNS) dysfunction resulting from prenatal alcohol exposure (PAE) is the most debilitating aspect of fetal alcohol spectrum disorders (FASDs). Affected children exhibit numerous cognitive and behavioural deficits which can severely affect quality of life. As the diagnosis of FASDs often requires specially trained physicians, there is a need for sensitive and specific tools that screen PAE-related CNS dysfunction in order to identify individuals who require further consultation. Additionally, objective measures of intervention end-points are critical to ass
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17

Tao, Hung-Tau, and 陶宏姿. "The Impact of Central Nervous System Treatment on Cognitive Function of Children with Acute Lymphoblastic Leukemia and Its Related Factors." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/92656191566714898823.

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碩士<br>國立臺灣大學<br>護理學研究所<br>91<br>This quantitative study was aimed to investigate differences of cognitive function and school grades of the children with acute lymphoblastic leukemia (ALL). This study focused on the central nervous system prophylaxis during anti-leukemia therapy and compared the subjects’ performance with their peers. The case subjects received 18 Gy cranial radiotherapy (TPOG-ALL-93-HR) or intrathecal methotrexate (TPOG-ALL-93-SR), and each therapy was accompanied with intravenous high-dose methotrexate. The study population consisted of 16 children with leukemia a
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18

Hanwell, Heather. "Vitamin D Status and its Contribution to Multiple Sclerosis Risk: Insights Gained through the Study of Children with Central Nervous System Demyelination." Thesis, 2012. http://hdl.handle.net/1807/33883.

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Acute demyelination in children may be a monophasic illness or the sentinel attack of multiple sclerosis (MS) – a chronic inflammatory neurodegenerative demyelinating disease. MS risk is largely determined during childhood and vitamin D may protect against MS. The primary objective of this thesis was to evaluate vitamin D status in children presenting with acute demyelinating syndromes (ADS) as a potential contributor to MS outcome. The LIAISON “25 OH Vitamin D TOTAL” assay was validated to assess the biomarker of vitamin D status – serum 25-hydroxyvitamin D (25(OH)D) concentrations. Consecuti
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19

Verhey, Leonard Herman. "MRI in the Prediction and Diagnosis of Pediatric-onset Multiple Sclerosis: Insights from Children with Incident CNS Demyelination." Thesis, 2012. http://hdl.handle.net/1807/34952.

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An acute demyelinating syndrome (ADS) in a child may be a monophasic illness or may represent the incident attack of multiple sclerosis (MS) – an inflammatory demyelinating neurodegenerative disorder affecting the brain, spinal cord and optic nerves. The central objective of this dissertation was to identify MRI parameters present at ADS that predict MS diagnosis. A scoring tool was first created containing 14 parameters identified from the literature and demonstrating substantial inter-rater agreement (Cohen’s kappa values ≥0.6). Children aged <16 years were enrolled at incident ADS and are c
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20

Strehlau, Renate. "Neurodevelopmental delays in children with perinatally acquired human immunodeficiency virus infection, with respect to antiretroviral therapy initiation and virological suppression." Thesis, 2013.

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A research report submitted to the Faculty of Health Sciences, the University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Science in Medicine in Child Health Neurodevelopment Johannesburg, 2013<br>Human Immunodeficiency Virus (HIV) infection in infancy may influence the developing brain and lead to adverse neurodevelopmental consequences. We aim to describe the neurodevelopmental characteristics of a cohort of young children infected with HIV prior to antiretroviral therapy (ART) initiation and after achieving viral suppression.
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21

Chen, Mei-Tsz, and 陳美慈. "The estimation of incidence and survival rates of leukemia, lymphoma and central nervous system & brain tumor in children from birth cohorts of 1996-2002 in Taiwan." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/39984544647215432137.

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碩士<br>中國醫藥大學<br>生物統計研究所碩士班<br>100<br>Background The estimation of childhood cancer using Taiwan nationwide data has never been reported. The objective of the current study was to estimate the incidence rates and 5-year survival rates of top three childhood cancers followed up to the 2008: leukemia, lymphoma, and central nervous system (CNS) and brain cancer from birth cohorts of 1996-2002 in Taiwan. Methods We conducted a population-based retrospective cohort study consisting of 1996-2002 birth cohorts for Taiwan between 1996 and 2002 and followed it up to 2008. The datasets of the study were
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22

Stănescu, Dan Florin [Verfasser]. "Children of parents with acute central nervous system injuries in Romania : assessment of mental health needs and evaluation of an innovative preventive family intervention / vorgelegt von Dan Florin Stănescu." 2007. http://d-nb.info/985124377/34.

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23

Auger, Jean-Philippe. "Étude de la pathogenèse de l’infection et de l’inflammation causées par des souches de Streptococcus suis de différentes origines." Thèse, 2018. http://hdl.handle.net/1866/21809.

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