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1

Chiu, Pui-man. "Molecular genetics of cervical cancer from chromosome number alterations to aberrant gene expressions /". Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43085544.

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2

Liu, Si Stephanie. "Cervical cancer and radiotherapy: study on apoptosis and its related genes, with special interest on p73". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31245766.

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Chiu, Pui-man y 趙佩文. "Molecular genetics of cervical cancer: from chromosome number alterations to aberrant gene expressions". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085544.

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4

Lundberg, Mathias. "Cloning and characterization of human glutaredoxins /". Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-261-2.

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5

Abelin, Törnblom Susanne. "Mediators of cervical ripening in preterm birth : experimental and clinical investigations /". Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-305-1/.

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6

Lai, Tung-on Anthony y 黎東安. "PRKAA1 gene amplification in cervical cancer and precursors: a study in cytology samples". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45153048.

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7

Ho, Kam-tai y 何金娣. "To reveal the gene copy status of MUC1 in cervical neoplasia and precursor lesions by real-time PCR". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44659799.

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8

Vadlamuri, Satya Vijayanand. "Genetic evaluation of cytochrome-P450 expression in smoking and nonsmoking women". Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=1806.

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Thesis (Ph. D.)--West Virginia University, 2001.
Title from document title page. Document formatted into pages; contains xiv, 150 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 104-120).
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9

Schöffel, Marion. "Die Expression von PAX9 im gesunden und dysplastischen Epithel und in invasiven Karzinomen des Ösophagus und der Cervix uteri eine immunhistochemische Studie /". [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973910062.

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10

Mo, Bilan. "5-fluorouracil-induced apoptosis and altered expression of apoptosis-regulating proteins in a model system for multistage cervical carcinogenesis". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0031/MQ62401.pdf.

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11

Weyn, Christine. "Human papillomavirus prevalence and expression in trophoblastic and cervical cells". Doctoral thesis, Universite Libre de Bruxelles, 2010. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210012.

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Human papillomavirus (HPV) is a double-stranded DNA virus, typically infecting mucosal or cutaneous epithelial keratinocytes. Today, more than 118 different HPV types have been formally described. Sexual transmission of mucosal HPVs is very common and generally asymptomatic, but HPV infection can be associated with benign lesions such as condylomata acuminata or, in rare cases, with malignant lesions such as cervical cancer. Two prophylactic vaccines are currently available in Europe, protecting against HPV-16 and HPV-18 (Cervarix&63720;) or against HPV-6, HPV-11, HPV-16 and HPV-18 (Gardasil&63720;). In order to assess the impact of the vaccination program, it is mandatory to obtain geographically widespread date on the baseline HPV prevalence and type distribution in cervical samples from women, presenting or not, normal or abnormal cytologic or histologic results. We undertook an epidemiological study in the Capital Region of Brussels to determine the HPV prevalence and type-distribution in 1526 cervical samples of women presenting a cytology within normal limits (WINL), atypical squamous cells of undetermined significance (ASC-US), low-grade squamous intra-epithelial lesions (LSIL), high-grade squamous intra-epithelial lesions (HSIL) or invasive cervical cancer (ICC). The HPV prevalence was 10.8% (95%CI: 8.8-12.8) for NILM, 34.5% (95%CI: 28.3-40.8) for ASC-US, 54.0% (95%CI: 47.4-60.6) for LSIL and 100% for HSIL and ICC. With an HPV-16 and HPV-18 prevalence of 63.3% (95%CI: 44.1-67.7) and 73.5% (95%CI: 63.0-84.0) in mono-infected HSIL and ICC, respectively, HPV 16/18 L1 VLP vaccines would be expected to significantly reduce the management and treatment of women suffering from HSIL and ICC in the Capital Region of Brussels. We also detected HPV-30, HPV-53, HPV-66 and HPV-68 in mono-infected HSIL and ICC samples, possibly providing arguments for the reconsideration of the carcinogenicity of these types.

Vertical transmission of HPV was also previously reported, but in most cases one could not exclude a placental contamination by HPV positive cells from an infected birth canal. In order to confirm that the placenta can be infected with HPV, we analysed residual cells from 35 transabdominally obtained placental samples from pregnant women undergoing chorionic villous sampling for screening of suspected foetal abnormalities and found that two samples were positive for HPV-16 and HPV-62, respectively. The clinical importance of these results remains to be elucidated, but the previously observed association between placental HPV infection and pregnancy loss might gain further in importance. HPV gene regulation in placental trophoblastic cells has not been studied so far. We studied the HPV-16 early gene expression regulation in transiently transfected monolayer cultured trophoblastic cells with an HPV-16 long control region (LCR) driven reporter plasmid. We observed important differences in constitutive HPV-16 LCR activities between trophoblastic cell lines and could identify progesterone as an important inducer of HPV-16 early gene expression. Steroid hormones are induced during pregnancy and could therefore lead to an enhanced expression of the E5, E6 and E7 proteins upon placental HPV infection. Since these proteins were previously shown to affect trophoblast adhesion, survival, migration and invasion, their enhanced expression might eventually contribute to pregnancy loss. We furthermore found that the transcription of episomally maintained HPV-16 is not regulated by E2 or E1, but by E5, E6 and/or E7.


Doctorat en Sciences biomédicales et pharmaceutiques
info:eu-repo/semantics/nonPublished

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12

Ströhle, Ruth [Verfasser]. "Influence of cycle stage, age and biopsy score on oxytocin receptor gene expression and distribution in the cervix and uterus of non-pregnant mares / Ruth Ströhle". Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1196803412/34.

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13

Carlson, Mark Wallace. "Gene expression profiling and modeling of cervical cancer". Thesis, 2006. http://hdl.handle.net/2152/2684.

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14

Moela, Pontsho. "Functional studies of the RBBP6 (retinoblastoma binding protein 6) gene and its related genes in breast and cervical cancer : a promising diagnostic and management assay for cancer progression". Thesis, 2016. http://hdl.handle.net/10539/21249.

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A thesis submitted to the Faculty of Science under the school of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Doctor of Philosophy. Gauteng, Johannesburg, 2016.
Overexpression of RBBP6 in cancers of the colon, lung and oesophagus makes it a potential target in anticancer therapy. This is especially important because it associates with the tumour suppressor gene p53, inactivation of which has been linked to over 50% of all cancer types. Cancer is an enormous burden of a disease globally. Today, more people die from cancer than HIV/AIDS, tuberculosis and malaria combined. And in females, breast and cervical malignancies remain the most common types. Currently, cervical cancer is the most diagnosed gynaecological cancer type, whose mortality rate is the highest in developing countries due to the asymptomatic nature of the disease coupled with inadequate cancer control tools and facilities. Breast cancer incidence rate has increased beyond that of lung cancer, making it the most common malignancy among women.
GR2016
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15

Qadadri, Brahim. "Human papillomavirus type distribution in cervical cancer in Indiana and Botswana". Thesis, 2014. http://hdl.handle.net/1805/5223.

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Indiana University-Purdue University Indianapolis (IUPUI)
In this study we compared the distribution of HPV types in cervical cancer specimens from women living in either Indiana or Botswana. Paraffin-embedded blocks of formalin-fixed cervical cancer specimens were identified from women living in Indiana (n=51) or Botswana (n=171)
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16

Schöffel, Marion [Verfasser]. "Die Expression von PAX9 im gesunden und dysplastischen Epithel und in invasiven Karzinomen des Ösophagus und der Cervix uteri : eine immunhistochemische Studie / Marion Schöffel". 2004. http://d-nb.info/973910062/34.

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