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1

Singh, Jagwinder, and Shivani Saini. "Importance of CEM in CRM-CL framework." Journal of Modelling in Management 11, no. 1 (2016): 91–115. http://dx.doi.org/10.1108/jm2-05-2014-0038.

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Purpose – The purpose of this paper is to propose a model to understand the role of customer relationship management efforts in building, sustaining and enhancing customer loyalty (CL). Design/methodology/approach – This paper reviews extant literature in customer relationship management (CRM), customer experience management (CEM) and CL, with a particular emphasis on exploring the relationships between these proposed domains. Findings – The CRM efforts, customer acquisition, retention and experience, are suggested to have positive influence on attitudinal and behavioural loyalty. A model for
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2

Al-Zadjali, Mohamed, and Kamla Ali Al-Busaidi. "Empowering CRM Through Business Intelligence Applications." International Journal of Knowledge Management 14, no. 4 (2018): 68–87. http://dx.doi.org/10.4018/ijkm.2018100105.

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The application of business intelligence (BI) techniques for knowledge discovery and decision support empowers organizations in different functions. This article examines the impacts of BI on customer relationship management (CRM) functions (marketing, sales and customer services) in the telecommunications sector. The literature found that BI application in CRM in a telecommunications context is limited but necessary due to the high rate of competition between service providers and the massive data generated by subscribers. This study surveyed employees' perspectives from telecommunications co
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3

Becker, Jan U., Goetz Greve, and Sönke Albers. "Left Behind Expectations - How to Prevent CRM Implementations from Failing." GfK Marketing Intelligence Review 2, no. 2 (2010): 34–41. http://dx.doi.org/10.2478/gfkmir-2014-0061.

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Abstract This article discusses performance drivers of CRM projects and is particularly relevant for managers seeking to optimize their companies CRM efforts. Despite the billions of dollars that have been spent on the implementation of customer relationship management (CRM) systems, many of the adopting companies are unhappy with the results. This can be due to two reasons: first, either the CRM projects are poorly implemented and thus do not perform accordingly, or, second, companies expect too much from CRM systems. This research examines how technological and organizational implementations
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4

Liu, Yi-Yuan. "Does Technology Acceptance Change the Way from CRM to Customer Loyalty?" International Journal of E-Services and Mobile Applications 2, no. 3 (2010): 44–56. http://dx.doi.org/10.4018/jesma.2010070103.

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This study explores the moderating effect of technology acceptance on the relationship between customer relationship management (CRM) in terms of distribution and tailor-made functions and customer loyalty in the banking industry. The author uses LISREL two-group path analysis to find the variances between high and low technology acceptance. Data collected from the customers of nine retail banks show that commitments have a mediating effect on the relationship between the tailor-made function of CRM and customer loyalty, while technology acceptance has significant effects on both relationships
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5

Farid Shamsudin, Mohd, Mohd Fikri Ishak, Muhammad Asyraf Hashim, Milad Abdel Nabi, Mohd Faizun Mohamad Yazid, and Anis Abdul Razak. "PRELIMINARY ANALYSIS ON RELATIONSHIP OF CRM FUNCTIONS IMPLEMENTATION TOWARDS FIRM’S BUSINESS PERFORMANCE." Humanities & Social Sciences Reviews 7, no. 1 (2019): 113–20. http://dx.doi.org/10.18510/hssr.2019.7114.

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Purpose of Study: The purpose of this preliminary study is to determine the reliability and validity of the instrument used and feasible for full-scale analysis of the aforementioned studied phenomenon. PLS-SEM is employed in this preliminary study that utilised SmartPLS 3.0.
 Methodology: Drawing on RBV (resource-based view) the implementation of customer relationship management (CRM) functions in hotel industry had become a central strategy in determining competitive advantage. Empirical studies had documented that small and medium hotels had also embraced on customer-centric business p
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6

Kamalova, G. B., N. A. Vodolazkina, and K. I. Aklbekov. "INFORMATION CRM SYSTEMS IN ORGANIZATIONAL AND MANAGEMENT ACTIVITIES OF TECHNICIANS-PROGRAMMERS." BULLETIN Series of Physics & Mathematical Sciences 71, no. 3 (2020): 220–24. http://dx.doi.org/10.51889/2020-3.1728-7901.33.

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Allocation of organizational and managerial activity as an independent type in the structure of the professional activity of a technician-programmer, including the implementation of such organizational and managerial functions as planning and teamwork, making and implementing managerial decisions, establishing and maintaining internal and external communications, evaluating and developing professional and career advancement, project management, will allow him to effectively organize activities, both his own and the division of the organization entrusted to him. One of the main organizational a
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7

O’Neill, Ryan S., Todd A. Schoborg, and Nasser M. Rusan. "Same but different: pleiotropy in centrosome-related microcephaly." Molecular Biology of the Cell 29, no. 3 (2018): 241–46. http://dx.doi.org/10.1091/mbc.e17-03-0192.

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An intimate link between centrosome function and neurogenesis is revealed by the identification of many genes with centrosome-associated functions that are mutated in microcephaly disorders. Consistent with the major role of the centrosome in mitosis, mutations in these centrosome-related microcephaly (CRM) genes are thought to affect neurogenesis by depleting the pool of neural progenitor cells, primarily through apoptosis as a consequence of mitotic failure or premature differentiation as a consequence of cell cycle delay and randomization of spindle orientation. However, as suggested by the
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8

Lipiäinen, Heini Sisko Maarit. "CRM in the digital age: implementation of CRM in three contemporary B2B firms." Journal of Systems and Information Technology 17, no. 1 (2015): 2–19. http://dx.doi.org/10.1108/jsit-06-2014-0044.

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Purpose – The purpose of this study was to contribute to the current discussion on digitization in companies’ marketing from a customer relationship management (CRM) perspective by examining the role and objectives of CRM and the exploitation of social media to serve the objectives of CRM in contemporary business-to-business (B2B) companies. Design/methodology/approach – The data are collected through semi-structured themed interviews with key marketing/sales managers from three B2B firms. Findings – CRM seems to be moving closer to the company’s core activity and becoming everybody’s business
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9

Berliandaldo, Mahardhika, Achmad Chodiq, Sutarno Sutarno, and Heru Eko Prasetyo. "IMPLEMENTASI MODEL CUSTOMER RELATIONSHIP MANAGEMENT UNTUK FUNGSI LAYANAN UMUM PADA ERA TATANAN BARU." Journal Publicuho 4, no. 2 (2021): 225. http://dx.doi.org/10.35817/jpu.v4i2.17703.

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Customer Relationship Management or CRM is a new approach to managing relationships between organizations and customers. In the era of the new order, especially during the current Covid-19 pandemic, digitizing public service functions carried out by the General Bureau of LIPI will play an important role in supporting the smooth running of the organization's operations. Customer satisfaction is highly dependent on the service process provided by executing service functions. In order for public service functions to run properly, it is necessary to carry out analysis in exploiting customer data i
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10

Singh, Anurag. "Drive Customer Experience for Relationship Management through Actionable Social CRM." International Journal of Customer Relationship Marketing and Management 6, no. 4 (2015): 57–76. http://dx.doi.org/10.4018/ijcrmm.2015100104.

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Social CRM is gradually stirring into the conventional business strategies in spite of much hue and cry for unsecured process and stepping. Seeing people networked for the sustainable advantages of the companies, they are now being enabled by web 2.0 technologies. Web 2.0 technology is a hopeful breakthrough to modernize the CRM. In the process and implementation of the strategy, few of corporate giants have already jumped into the social CRM, and few are in the process of comprehension and the adoption. This paper aims to portray the process of social media in monitoring and fostering the rel
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11

Ou, Yan Qun, Li Zhou, and Yu Ping Fang. "Application Research of Data Warehouse in CRM." Advanced Materials Research 591-593 (November 2012): 854–57. http://dx.doi.org/10.4028/www.scientific.net/amr.591-593.854.

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Customer relationship management (CRM) is an integral part in the manufacturing enterprise information. The content of CRM is based on customer information and business transaction data, and using computer information technology to deeply analysis massive data of data warehouse. The purpose is to identify customers’ different features and analyze customer behaviors, then dig out the information of commercial value to help business planning and decision-making related business activities. The thesis introduces the system of the CRM based on Data Warehouse: to describe and predict the model of e
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12

Zhang, Qiang, Lan Shen, Deyong Ren, et al. "Characterization of the CRM Gene Family and Elucidating the Function of OsCFM2 in Rice." Biomolecules 10, no. 2 (2020): 327. http://dx.doi.org/10.3390/biom10020327.

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The chloroplast RNA splicing and ribosome maturation (CRM) domain-containing proteins regulate the expression of chloroplast or mitochondrial genes that influence plant growth and development. Although 14 CRM domain proteins have previously been identified in rice, there are few studies of these gene expression patterns in various tissues and under abiotic stress. In our study, we found that 14 CRM domain-containing proteins have a conservative motif1. Under salt stress, the expression levels of 14 CRM genes were downregulated. However, under drought and cold stress, the expression level of so
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13

Mayhew, David L., Jerry L. Mayhew, and John S. Ware. "Effects of Long-term Creatine Supplementation on Liver and Kidney Functions in American College Football Players." International Journal of Sport Nutrition and Exercise Metabolism 12, no. 4 (2002): 453–60. http://dx.doi.org/10.1123/ijsnem.12.4.453.

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The purpose of this study was to determine the effect of long-term Cr supplementation on blood parameters reflecting liver and kidney function. Twenty-three members of an NCAA Division II American football team (ages = 19–24 years) with at least 2 years of strength training experience were divided into a Cr monohydrate group (CrM, n = 10) in which they voluntarily and spontaneously ingested creatine, and a control group (n = 13) in which they took no supplements. Individuals in the CrM group averaged regular daily consumption of 5 to 20 g (mean ± SD = 13.9 ± 5.8 g) for 0.25 to 5.6 years (2.9 ±
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14

Zhang, Qiang, Lan Shen, Zhongwei Wang, et al. "OsCAF1, a CRM Domain Containing Protein, Influences Chloroplast Development." International Journal of Molecular Sciences 20, no. 18 (2019): 4386. http://dx.doi.org/10.3390/ijms20184386.

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The chloroplast RNA splicing and ribosome maturation (CRM) domain proteins are involved in the splicing of chloroplast gene introns. Numerous CRM domain proteins have been reported to play key roles in chloroplast development in several plant species. However, the functions of CRM domain proteins in chloroplast development in rice remain poorly understood. In the study, we generated oscaf1 albino mutants, which eventually died at the seedling stage, through the editing of OsCAF1 with two CRM domains using CRISPR/Cas9 technology. The mesophyll cells in oscaf1 mutant had decreased chloroplast nu
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15

Shutts, G. J., and T. N. Palmer. "Convective Forcing Fluctuations in a Cloud-Resolving Model: Relevance to the Stochastic Parameterization Problem." Journal of Climate 20, no. 2 (2007): 187–202. http://dx.doi.org/10.1175/jcli3954.1.

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Abstract Idealized cloud-resolving model (CRM) simulations spanning a large part of the tropical atmosphere are used to evaluate the extent to which deterministic convective parameterizations fail to capture the statistical fluctuations in deep-convective forcing, and to provide probability distribution functions that may be used in stochastic parameterization schemes for global weather and climate models. A coarse-graining methodology is employed to deduce an effective convective warming rate appropriate to the grid scale of a forecast model, and a convective parameterization scheme is used t
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16

Parry, William. "DYNAMICAL ZETA FUNCTIONS FOR PIECEWISE MONOTONE MAPS OF THE INTERVAL (CRM Monograph Series 4)." Bulletin of the London Mathematical Society 28, no. 3 (1996): 327–29. http://dx.doi.org/10.1112/blms/28.3.327.

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17

Dos Santos, José Gonalo. "Data Mining as Support for Customer Relationship Management: A Case Study." INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY 13, no. 11 (2014): 5113–20. http://dx.doi.org/10.24297/ijct.v13i11.2780.

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This article describes the data mining application to CRM - Customer Relationship Management. The article starts with an introduction showing the importance of the CRM strategy for the company, after it’s introduced the theoretical about CRM, Knowledge Discovery Database and its stages, with emphasis to the mining stage and concludes with presentation of a case study and the conclusions. For the case study it was developed a prototype of an information system of a bookstore, it was implemented, beyond the conventional functions, the association rules discovery algorithm. The implementation o
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18

Pauls, Stefan, Debbie K. Goode, Libero Petrone, Paola Oliveri, and Greg Elgar. "Evolution of lineage-specific functions in ancient cis -regulatory modules." Open Biology 5, no. 11 (2015): 150079. http://dx.doi.org/10.1098/rsob.150079.

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Morphological evolution is driven both by coding sequence variation and by changes in regulatory sequences. However, how cis -regulatory modules (CRMs) evolve to generate entirely novel expression domains is largely unknown. Here, we reconstruct the evolutionary history of a lens enhancer located within a CRM that not only predates the lens, a vertebrate innovation, but bilaterian animals in general. Alignments of orthologous sequences from different deuterostomes sub-divide the CRM into a deeply conserved core and a more divergent flanking region. We demonstrate that all deuterostome flanking
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19

Ren, Wen Ju, Ya Hui Hu, Tong Jian Zhang, and Ming Xing Li. "The Correlation between CRM Strategy for City Commercial Banks and Core Competency Cultivation-Evidence from China." Advanced Materials Research 452-453 (January 2012): 980–85. http://dx.doi.org/10.4028/www.scientific.net/amr.452-453.980.

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In order to reveal the incentive functions of customer relationship management (CRM) strategy in the process of core competency cultivation, the structure equation modeling (SEM) is used in this paper. By research hypothesis, model deduction, reliability and verification test, and model checking, SEM can effectively reveal the correlation between CRM strategy and core competence cultivation in Chinese city commercial banks. For illustration, the collected copies are 300 banks, and 298 copies are valid. The sample ratio of sample data and indicators is 6:1, which meets the basic requirements fo
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20

Yulistiani, Dwi, Wisri Puastuti, Budi Haryanto, Agung Purnomoadi, M. Kurihara, and Amlius Thalib. "COMPLETE RUMEN MODIFIER SUPPLEMENTATION IN CORN COB SILAGE BASAL DIET OF LAMB REDUCES METHANE EMISSION." Indonesian Journal of Agricultural Science 18, no. 1 (2017): 33. http://dx.doi.org/10.21082/ijas.v18n1.2017.p33-42.

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<p>Feeding animal with fibrous materials such as corn cob will emit methane. Complete rumen modifier (CRM) is an improved feed additive comprised a mixture of Sapindus rarak, sesbania, albizia leaves and minerals that functions as a methane inhibitor. The study aimed to determine the effect of CRM supplementation on the feed intake, nutrient digestibility, rumen fermentation, methane emission and growth of lambs. The experiment was designed in a complete randomized block, four levels of CRM (0%, 1%, 2%, and 3%), six group of 24 male lambs per treatment based on the body weight. Basal die
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21

Nehari-Talet, Amine, Samer Alhawari, and Haroun Alryalat. "The Outcome of Knowledge Process for Customer of Jordanian Companies on the Achievement of Customer Knowledge Retention." International Journal of Knowledge Management 6, no. 1 (2010): 44–61. http://dx.doi.org/10.4018/jkm.2010103003.

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Organizations have increasingly recognized the importance of managing customer relationships, and Knowledge Management (KM) from the perspective of a process approaches assure positive impact on customer retention. Many organizations are turning to Customer Relationship Management (CRM) to better serve customers and facilitate closer relationships. This paper investigates how Knowledge Process for customers is used in practice by Jordanian companies to achieve Customer Knowledge Retention. The current practice is based on the data collected from 156, randomly drawn and reported from a survey o
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22

Asakura, Yukari, and Alice Barkan. "A CRM Domain Protein Functions Dually in Group I and Group II Intron Splicing in Land Plant Chloroplasts." Plant Cell 19, no. 12 (2007): 3864–75. http://dx.doi.org/10.1105/tpc.107.055160.

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23

Law, J. Randolph, and Terry J. McFadden. "Training and Evaluating Team Process Skills in the Commercial Aviation Environment." Proceedings of the Human Factors Society Annual Meeting 36, no. 17 (1992): 1346–50. http://dx.doi.org/10.1518/107118192786749441.

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The majority of aviation incidents and accidents are attributable to human error (Billings & Reynard, 1984). Most of these human errors involve the ineffective use of team process factors, which are often referred to as Crew Resource Management (CRM) skills in the commercial aviation literature (Helmreich & Foushee, in press). In addition to these applied concerns, a revised version of McGrath's (1964) theory of group performance (Foushee & Helmreich, 1988) suggests that one must analyze the process (i.e., team process) by which a group's inputs (e.g., personality, attitudes) are t
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24

., Medha. "Customer Segmentation using Data Mining Techinique." International Journal for Research in Applied Science and Engineering Technology 9, no. VII (2021): 996–98. http://dx.doi.org/10.22214/ijraset.2021.36105.

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Data mining technique can help implementing customer relationship management dimensions namely customer identification, customer attraction, customer retention and customer development . Various Data mining functions can be used to implement CRM elements . This review paper is focused on one of the element of customer identification that is customer segmentation and its implentation using K-means clustering technique. It discuses in breif about the K-means Algorithm.
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Yang, Zhi Gang, Li Sun, and Xiao Yang Yu. "Design and Implementation of a Data Warehouse ETL Tray Program." Applied Mechanics and Materials 385-386 (August 2013): 1684–88. http://dx.doi.org/10.4028/www.scientific.net/amm.385-386.1684.

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This paper presents an ETL system for a data warehouse designed for a PVC profile manufacturing enterprise. The system implements the data extraction, data transformation and load from the data sources of ERP system, CRM system and production line operation data collection system. The ETL requirements are discussed. The system design and implementation methods, including system structure, functions, data processing methods as well as tray program implementation are addressed.
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26

Tarasova, Anna, Anna Polukhina, and Avdykerim Arnaberdiyev. "Information Support for Travel Agency Performance." International Journal of Recent Contributions from Engineering, Science & IT (iJES) 8, no. 4 (2020): 69. http://dx.doi.org/10.3991/ijes.v8i4.17669.

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<p>Internet technologies create new platforms for the sale of goods and services, however, their emergence arise new issues of how to attract and retain users. Modern Internet users enjoy freedom of choice, they can easily find travel services, or skip them just by closing the browser tab. That is how Customer Relationship Management (CRM) systems were introduced to build and manage efficiently good user relationships. This article discusses the main functions of CRM, according to the classification of The Center for Research on Information Technology and Organizations (the University of
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27

Arakawa, Yuya, Yuya Sugahara, Michiko Matsushita, et al. "Factor XII Osaka: Abnormal factor XII with partially defective prekallikrein cleavage activity." Thrombosis and Haemostasis 105, no. 03 (2011): 473–78. http://dx.doi.org/10.1160/th10-02-0123.

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SummaryA healthy Japanese male had reduced factor XII (FXII) activity (35%) in contrast to normal antigen levels (81%). The F12 of this proband had a 9775G to C mutation in exon 10 and an 11276G to A mutation in exon 13 that resulted in two amino acid substitutions of Ala324Pro (GCG→CCG) in the proline-rich connecting region and Gly531Glu (GGG→GAG) near the active Ser544 in the catalytic domain. His father had the nucleotide 46T/T and a heterozygous 9775G/C mutation. The FXII activity (32%) and antigen level (38%) of the father were about half that of normal individuals with 46T/T, suggesting
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28

Lau, Henry, Dilupa Nakandala, Premaratne Samaranayake, and Paul Shum. "A hybrid multi-criteria decision model for supporting customer-focused profitability analysis." Industrial Management & Data Systems 116, no. 6 (2016): 1105–30. http://dx.doi.org/10.1108/imds-10-2015-0410.

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Purpose – Strategic analysis of customer profitability for assessing market segmentation and reconfiguring customer relationship management (CRM) activities remains the key factor for achieving high return on CRM investment. The purpose of this paper is to map the profit-based ranking of corporate customers into the current market segments, with a view of determining the relative profitability of each market segment. Design/methodology/approach – This study develops a novel model that combines activity-based costing (ABC), CRM, fuzzy analytic hierarchy process (AHP), and technique for order pr
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Song, Fengfei, and Guang J. Zhang. "Understanding and Improving the Scale Dependence of Trigger Functions for Convective Parameterization Using Cloud-Resolving Model Data." Journal of Climate 31, no. 18 (2018): 7385–99. http://dx.doi.org/10.1175/jcli-d-17-0660.1.

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As the resolution of global climate model increases, whether trigger functions in current convective parameterization schemes still work remains unknown. In this study, the scale dependence of undilute and dilute dCAPE, Bechtold, and heated condensation framework (HCF) triggers is evaluated using the cloud-resolving model (CRM) data. It is found that all these trigger functions are scale dependent, especially for dCAPE-type triggers, with skill scores dropping from ~0.6 at the lower resolutions (128, 64, and 32 km) to only ~0.1 at 4 km. The average convection frequency decreases from 14.1% at
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Welda, Welda, Bagus Baskara Sukarma, and Emmy Febriani Thalib. "Sistem Informasi Penjualan Dengan Fitur Customer Relationship Management (CRM) Pada Tria Salon Berbasis Web." Jurnal Sistem Informasi dan Komputer Terapan Indonesia (JSIKTI) 1, no. 3 (2019): 165–74. http://dx.doi.org/10.33173/jsikti.31.

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Sales is a transaction carried out by two or more parties between one person to another with a valid payment that generates an income. One of the factors of success of sales is to maintain good relationships with customers, such as giving special promotions to Pelaggan so that customers will continue to come to buy products or services offered by a company.In this study found problems such as the difficulty of determining customer loyalty, the difficulty of determining the product that must be stocked a lot, the difficulty in recording transactions because of the possibility of missing or inco
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Ahmed, Bashar Shahir, Mohamed Larabi Ben Maâti, and Mohammed Al-Sarem. "Predictive Data Mining Model for Electronic Customer Relationship Management Intelligence." International Journal of Business Intelligence Research 11, no. 2 (2020): 1–10. http://dx.doi.org/10.4018/ijbir.2020070101.

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The rising adoption of e-CRM strategies in marketing and customer relationship management has necessitated to more needs especially where a specific customer segment is targeted and the services are personalized. This paper presents a distributed data mining model using access-control architecture in a bid to realize the needs for an online CRM that intends to deliver web content to a specific group of customers. This hybrid model utilizes the integration of the mobile agent and client server technologies that could easily be updated from the already existing web platforms. The model allows th
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32

G. Inyang, Udoinyang, Okure O. Obot, Moses E. Ekpenyong, and Aliu M. Bolanle. "Unsupervised Learning Framework for Customer Requisition and Behavioral Pattern Classification." Modern Applied Science 11, no. 9 (2017): 151. http://dx.doi.org/10.5539/mas.v11n9p151.

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Maintaining healthy organization-customers relationship has positive influence on customers’ behavioral tendencies as regards preference to products and services, buying behavior, loyalty, satisfaction, and so on. To achieve this, an in-depth analysis of customers’ characteristics and purchasing behavioral trend is required. This paper proposes a hybrid unsupervised learning framework consisting of k-means algorithm and self-organizing maps (SOMs) for customer segmentation and behavior analysis. K-means algorithm was used to partition the entire input space of customers’ transaction dataset in
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33

Mert, Ufuk, Alshaimaa Adawy, Elisabeth Scharff, et al. "TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors." Cancers 11, no. 8 (2019): 1167. http://dx.doi.org/10.3390/cancers11081167.

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Binding of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to the plasma membrane TRAIL-R1/-R2 selectively kills tumor cells. This discovery led to evaluation of TRAIL-R1/-R2 as targets for anti-cancer therapy, yet the corresponding clinical trials were disappointing. Meanwhile, it emerged that many cancer cells are TRAIL-resistant and that TRAIL-R1/-R2-triggering may lead to tumor-promoting effects. Intriguingly, recent studies uncovered specific functions of long ignored intracellular TRAIL-R1/-R2, with tumor-promoting functions of nuclear (n)TRAIL-R2 as the regulator of let-
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34

McIntosh, Richard J. "The H and K Family of Mock Theta Functions." Canadian Journal of Mathematics 64, no. 4 (2012): 935–60. http://dx.doi.org/10.4153/cjm-2011-066-0.

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AbstractIn his last letter to Hardy, Ramanujan defined 17 functionsF(q), |q| < 1, which he calledmockθ-functions. He observed that asqradially approaches any root of unity ζ at whichF(q) has an exponential singularity, there is aθ-functionTζ(q) withF(q) −Tζ(q) =O(1). Since then, other functions have been found that possess this property. These functions are related to a functionH(x,q), wherexis usuallyqrore2πirfor some rational numberr. For this reason we refer toHas a “universal” mockθ-function. Modular transformations ofHgive rise to the functionsK,K1,K2. The functionsKandK1appear in Rama
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35

Lischka, Peter, Claudia Rauh, Regina Mueller, and Thomas Stamminger. "Human Cytomegalovirus UL84 Protein Contains Two Nuclear Export Signals and Shuttles between the Nucleus and the Cytoplasm." Journal of Virology 80, no. 20 (2006): 10274–80. http://dx.doi.org/10.1128/jvi.00995-06.

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ABSTRACT Previous studies defined pUL84 of human cytomegalovirus as an essential regulatory protein with nuclear localization that was proposed to act during initiation of viral-DNA synthesis. Recently, we demonstrated that a complex domain of 282 amino acids within pUL84 functions as a nonconventional nuclear localization signal. Sequence inspection of this domain revealed the presence of motifs with homology to leucine-rich nuclear export signals. Here, we report the identification of two functional, autonomous nuclear export signals and show that pUL84 acts as a CRM-1-dependent nucleocytopl
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36

Azmi, Izwan, Norlida Abdul Hamid, Md Nasarudin Md Hussin, and Nik Ibtishamiah Ibrahim. "Logistics and supply chain management: The importance of integration for business processes." Journal of Emerging Economies and Islamic Research 5, no. 4 (2017): 73. http://dx.doi.org/10.24191/jeeir.v5i4.8838.

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This conceptual paper outlines the importance of integration in supply chain management (SCM) by linking the functions of logistics as it applies in strategic business process. Often, business processes are developed at the strategic level but are never identified precisely in logistics or in SCM. Strategic business processes like Customer Relationship Management (CRM), Supplier Relationship Management (SRM), Customer Service Management (CSM) and Demand Management are not directly linked to logistics or SCM. This paper identifies the literature that expressed the importance of integration and
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37

Vasileva, A. V., N. N. Kalmykov, S. A. Melnikov, and V. V. Solovyev. "Correlated signal model for a velocity simulator of a correlation radar meter." Journal of «Almaz – Antey» Air and Space Defence Corporation, no. 4 (December 30, 2016): 18–23. http://dx.doi.org/10.38013/2542-0542-2016-4-18-23.

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One of the functions of a correlation radar meter for measuring altitude and velocity vector components is measuring the velocity vector components based on comparing correlation properties of the signals received by spatially separated antennae. The CRM test and control equipment contains a simplified velocity simulator forming signal transport delays according to the values of axial and transverse velocity vector components. We consider a correlated signal model allowing us to imitate a reflected signal that makes it possible to measure parameter values by means of transport delays and the d
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38

Sartoros, Christine, Douglas M. Goltz, and Eric D. Salin. "Program Considerations for Simplex Optimization of Ion Lenses in ICP-MS." Applied Spectroscopy 52, no. 5 (1998): 643–48. http://dx.doi.org/10.1366/0003702981944292.

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The performance of an inductively coupled plasma mass spectrometer (ICP-MS) is dependent on the ion optic bias potentials. A discussion of the multielement optimization of the ICP-MS ion optics bias potentials using a Simplex algorithm is presented. Three objective functions were tested: a function developed by Leary; the combined ratio method (CRM); and the Euclidean distance from multicriteria target vector optimization. Both the Leary and the target vector optimization's performances were comparable, whereas the CRM optimizations placed an emphasis on obtaining similar signal intensities. E
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39

Lee, Kwanuk, and Hunseung Kang. "Roles of Organellar RNA-Binding Proteins in Plant Growth, Development, and Abiotic Stress Responses." International Journal of Molecular Sciences 21, no. 12 (2020): 4548. http://dx.doi.org/10.3390/ijms21124548.

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Organellar gene expression (OGE) in chloroplasts and mitochondria is primarily modulated at post-transcriptional levels, including RNA processing, intron splicing, RNA stability, editing, and translational control. Nucleus-encoded Chloroplast or Mitochondrial RNA-Binding Proteins (nCMRBPs) are key regulatory factors that are crucial for the fine-tuned regulation of post-transcriptional RNA metabolism in organelles. Although the functional roles of nCMRBPs have been studied in plants, their cellular and physiological functions remain largely unknown. Nevertheless, existing studies that have cha
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40

Lawrence, Kenneth D., Dinesh R. Pai, Ronald Klimberg, and Sheila M. Lawrence. "Enterprise Information System and Data Mining." International Journal of Business Intelligence Research 1, no. 3 (2010): 34–41. http://dx.doi.org/10.4018/jbir.2010070103.

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The advent of information technology and the consequent proliferation of information systems have lead to generation of vast amounts of data, both within the organization and across its supply chain. Enterprise information systems (EIS) have added to organizational complexity, and at the same time, created opportunities for enhancing its competitive advantage by utilizing this data for business intelligence purposes. Various data mining tools have been used to gain a competitive edge through these large data bases. In this paper, the authors discuss EIS-aided business intelligence and data min
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41

Amalnik, Morteza Sadegh. "A Reference Model and a vision for manufacturing system for 2030." INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY 14, no. 7 (2015): 5861–68. http://dx.doi.org/10.24297/ijct.v14i7.1899.

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The manufacturing enterprises are now experiencing high pressure of competition. In addition, the advancement in computer software, hardware, networks, information technologies and integration has been gradually reshaping the manufacturing companies by shifting from the industrial age to the information and knowledge era. Due to these elevated competitiveness and advanced computer technology, a number of new manufacturing and management strategies (e.g., Lean production, Just in time, Kaizen, Concurrent Engineering (CE), Cellular Manufacturing (CM), Agile manufacturing, Business process re-eng
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42

Isern, Germinal, and Giuseppe Sena. "Technical, Organizational and Cross-cultural issues associated with the deployment of Customer Relationship Management (CRM) in Transnational and Global Multicultural Organizations." Journal of Intercultural Management 6, no. 3 (2015): 187–96. http://dx.doi.org/10.2478/joim-2014-0029.

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Abstract In the past few years the way in which, organizations, companies and corporations structure themselves has given a 180 degrees turnaround, switching from a structure based in products to a structure based in customers. The first big change was the introduction and use of Enterprise Resource Planning Systems (ERP) like SAP and Oracle. Those ERP systems changed the way in which the information was managed in large corporations including now a central database and visualizing the structures and functions of the corporation by business processes and not by business areas. Also lately with
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43

Tang, Y., J. J. Jing, Y. Yang, and C. Xie. "Parameter Estimation of a Delay Time Model of Wearing Parts Based on Objective Data." Mathematical Problems in Engineering 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/419280.

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The wearing parts of a system have a very high failure frequency, making it necessary to carry out continual functional inspections and maintenance to protect the system from unscheduled downtime. This allows for the collection of a large amount of maintenance data. Taking the unique characteristics of the wearing parts into consideration, we establish their respective delay time models in ideal inspection cases and nonideal inspection cases. The model parameters are estimated entirely using the collected maintenance data. Then, a likelihood function of all renewal events is derived based on t
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44

Prüfer, Kirsten, and Julia Barsony. "Retinoid X Receptor Dominates the Nuclear Import and Export of the Unliganded Vitamin D Receptor." Molecular Endocrinology 16, no. 8 (2002): 1738–51. http://dx.doi.org/10.1210/me.2001-0345.

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Abstract Liganded and unliganded vitamin D receptors (VDRs) carry out distinct functions; both types of functions require heterodimerization with retinoid X receptors (RXRs). Our recent studies with fluorescent protein chimeras of VDR and RXR, termed GFP-VDR, YFP-RXR, and RXR-BFP, indicated that RXR regulates VDR functions in part by regulating subcellular localization. Here we explored the mechanisms of this regulation. Photobleaching experiments demonstrated that YFP-RXR and both unliganded and liganded GFP-VDR shuttle constantly between nucleus and cytoplasm. To characterize RXR import, we
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45

Wodrich, Harald, Jens Bohne, Ellen Gumz, Reinhold Welker, and Hans-Georg Kräusslich. "A New RNA Element Located in the Coding Region of a Murine Endogenous Retrovirus Can Functionally Replace the Rev/Rev-Responsive Element System in Human Immunodeficiency Virus Type 1 Gag Expression." Journal of Virology 75, no. 22 (2001): 10670–82. http://dx.doi.org/10.1128/jvi.75.22.10670-10682.2001.

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ABSTRACT Nuclear export of incompletely spliced RNAs is a prerequisite for retroviral replication. Complex retroviruses like human immunodeficiency virus (HIV) encode a viral transport factor (Rev), which binds to its target sequence on the RNA genome and directs it into the Crm-1-mediated export pathway. Other retroviruses, like Mason-Pfizer monkey virus, contain cis-acting constitutive RNA transport elements (CTE) which achieve nuclear export of intron-containing RNA via cellular transport factors. Here, we describe the identification and characterization of a novelcis-acting orientation-dep
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46

Saunders, Rebecca, Nuha Shiltagh, Keith Gomez, et al. "Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency." Thrombosis and Haemostasis 102, no. 08 (2009): 287–301. http://dx.doi.org/10.1160/th09-01-0044.

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SummaryFactor XI (FXI) functions in blood coagulation. FXI is composed of four apple (Ap) domains and a serine protease (SP) domain. Deficiency of FXI leads to an injury-related bleeding disorder, which is remarkable for the lack of correlation between bleeding symptoms and FXI coagulant activity (FXI:C).The number of mutations previously reported in our interactive web database (http://www.FactorXI.org) is now significantly increased to 183 through our new patient studies and from literature surveys. Eight novel missense mutations give a total of 120 throughout the FXI gene (F11).The most abu
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47

Carboni and Luca. "An Ontological Approach to the Description of Visual and Iconographical Representations." Heritage 2, no. 2 (2019): 1191–210. http://dx.doi.org/10.3390/heritage2020078.

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The perception of our heritage is based on sign-functions, which relate visual representations to cognitive types, allowing us to make perceptual judgements over physical objects. The recording of these types of assertions is paramount for the comprehension and analysis of our heritage. The article investigates a theoretical framework for the organization of information related to visual works on the basis of the identity and symbolic value of their single constituent elements. The framework developed is then used as a driver for the grounding of a new ontology called VIR (Visual Representatio
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48

Chen, Jingfei, Jialei Duan, Alina Montalbano, Boxun Li, Gary Hon, and Carole R. Mendelson. "Single-Cell RNA-Seq of Mouse Decidual Leukocytes Reveals Intriguing Gestational Changes in the Immune Cell Landscape and Effects of SRC-1/-2 Double-Deficiency." Journal of the Endocrine Society 5, Supplement_1 (2021): A753—A754. http://dx.doi.org/10.1210/jendso/bvab048.1532.

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Abstract Single-cell RNA-seq of Mouse Decidual Leukocytes Reveals Intriguing Gestational Changes in the Immune Cell Landscape and Effects of SRC-1/-2 Double-DeficiencyOur previous findings suggest that the fetus signals the mother when it is ready to be born through secretion of surfactant components/immune modulators, surfactant protein A (SP-A) and platelet-activating factor (PAF) by the fetal lung into amniotic fluid (AF). This occurs with increased proinflammatory cytokine expression by fetal AF macrophages (Mϕ), increased myometrial NF-κB activation and contractile (CAP) gene expression.
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49

Jeong, Sinwoo, Soobum Lee та Honghee Yoo. "Design Scalability Study of the Γ-Shaped Piezoelectric Harvester Based on Generalized Classical Ritz Method and Optimization". Electronics 10, № 16 (2021): 1887. http://dx.doi.org/10.3390/electronics10161887.

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This paper studies the design scalability of a Γ-shaped piezoelectric energy harvester (ΓEH) using the generalized classical Ritz method (GCRM) and differential evolution algorithm. The generalized classical Ritz method (GCRM) is the advanced version of the classical Ritz method (CRM) that can handle a multibody system by assembling its equations of motion interconnected by the constraint equations. In this study, the GCRM is extended for analysis of the piezoelectric energy harvesters with material and/or orientation discontinuity between members. The electromechanical equations of motion are
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50

Diniz, Márcio A., Sungjin Kim, and Mourad Tighiouart. "A Bayesian Adaptive Design in Cancer Phase I Trials Using Dose Combinations with Ordinal Toxicity Grades." Stats 3, no. 3 (2020): 221–38. http://dx.doi.org/10.3390/stats3030017.

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We propose a Bayesian adaptive design for early phase drug combination cancer trials incorporating ordinal grade of toxicities. Parametric models are used to describe the relationship between the dose combinations and the probabilities of the ordinal toxicities under the proportional odds assumption. Trial design proceeds by treating cohorts of two patients simultaneously receiving different dose combinations. Specifically, at each stage of the trial, we seek the dose of one agent by minimizing the Bayes risk with respect to a loss function given the current dose of the other agent. We conside
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