Acceder

Bibliografías temáticas / Eicosanoic acid Derivatives Physiological effects / Artículos de revistas

Siga este enlace para ver otros tipos de publicaciones sobre el tema: Eicosanoic acid Derivatives Physiological effects.

Artículos de revistas sobre el tema "Eicosanoic acid Derivatives Physiological effects"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 29 de enero de 2023

Crea una cita precisa en los estilos APA, MLA, Chicago, Harvard y otros

Elija tipo de fuente:

Consulte los 50 mejores artículos de revistas para su investigación sobre el tema "Eicosanoic acid Derivatives Physiological effects".

Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.

También puede descargar el texto completo de la publicación académica en formato pdf y leer en línea su resumen siempre que esté disponible en los metadatos.

Explore artículos de revistas sobre una amplia variedad de disciplinas y organice su bibliografía correctamente.

1

Calder, Philip C. "Eicosanoids." Essays in Biochemistry 64, no. 3 (August 18, 2020): 423–41. http://dx.doi.org/10.1042/ebc20190083.

Texto completo

Resumen

Abstract This article describes the pathways of eicosanoid synthesis, eicosanoid receptors, the action of eicosanoids in different physiological systems, the roles of eicosanoids in selected diseases, and the major inhibitors of eicosanoid synthesis and action. Eicosanoids are oxidised derivatives of 20-carbon polyunsaturated fatty acids (PUFAs) formed by the cyclooxygenase (COX), lipoxygenase (LOX) and cytochrome P450 (cytP450) pathways. Arachidonic acid (ARA) is the usual substrate for eicosanoid synthesis. The COX pathways form prostaglandins (PGs) and thromboxanes (TXs), the LOX pathways f

Los estilos APA, Harvard, Vancouver, ISO, etc.

2

Regulska, Magdalena, Magdalena Szuster-Głuszczak, Ewa Trojan, Monika Leśkiewicz, and Agnieszka Basta-Kaim. "The Emerging Role of the Double-Edged Impact of Arachidonic Acid- Derived Eicosanoids in the Neuroinflammatory Background of Depression." Current Neuropharmacology 19, no. 2 (December 31, 2020): 278–93. http://dx.doi.org/10.2174/1570159x18666200807144530.

Texto completo

Resumen

: Eicosanoids are arachidonic acid (AA) derivatives belonging to a family of lipid signalling mediators that are engaged in both physiological and pathological processes in the brain. Recently, their implication in the prolonged inflammatory response has become a focus of particular interest because, in contrast to acute inflammation, chronic inflammatory processes within the central nervous system (CNS) are crucial for the development of brain pathologies including depression. The synthesis of eicosanoids is catalysed primarily by cyclooxygenases (COX), which are involved in the production of

Los estilos APA, Harvard, Vancouver, ISO, etc.

3

Pope, Edward C., and Andrew F. Rowley. "The heart ofCiona intestinalis: eicosanoid-generating capacity and the effects of precursor fatty acids and eicosanoids on heart rate." Journal of Experimental Biology 205, no. 11 (June 1, 2002): 1577–83. http://dx.doi.org/10.1242/jeb.205.11.1577.

Texto completo

Resumen

SUMMARYEicosanoids are a group of oxygenated fatty-acid derivatives formed from C20 polyunsaturated fatty acids including arachidonic and eicosapentaenoic acids. In mammals, these compounds have been shown to be key molecules in several physiological processes including regulation of the vascular system. This study determined whether eicosanoids or their precursors are involved in the regulation of heart rate in the sea squirt Ciona intestinalis. Eicosanoid generation by both heart and blood cells was measured. The major lipoxygenase products formed were both derivatives of eicosapentaenoic ac

Los estilos APA, Harvard, Vancouver, ISO, etc.

4

Rodríguez, María, Pilar G. Rebollar, Simona Mattioli, and Cesare Castellini. "n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit." Animals 9, no. 10 (October 15, 2019): 806. http://dx.doi.org/10.3390/ani9100806.

Texto completo

Resumen

This review compares the effects of different n-3 polyunsaturated fatty acid (PUFA) sources on biological activity, physiological/reproductive endpoints, and health implications with a special emphasis on a rabbit case study. Linoleic acid (LA) and α-linolenic acid (ALA) are members of two classes of PUFAs, namely the n-6 and n-3 series, which are required for normal human health. Both are considered precursors of a cascade of molecules (eicosanoids), which take part in many biological processes (inflammation, vasoconstriction/vasodilation, thromboregulation, etc.). However, their biological f

Los estilos APA, Harvard, Vancouver, ISO, etc.

5

Wang, Hongyu, Erdu Ren, Xiaoe Xiang, Yong Su, and Weiyun Zhu. "Dynamic Changes in Serum Metabolomic Profiles of Growing Pigs Induced by Intravenous Infusion of Sodium Butyrate." Metabolites 10, no. 1 (January 1, 2020): 20. http://dx.doi.org/10.3390/metabo10010020.

Texto completo

Resumen

This study aimed to explore the dynamic changes in metabolite profiles and metabolism pathways in the serum of growing pigs by intravenous infusion of sodium butyrate (SB). Fourteen crossbred growing barrows (BW = 23.70 ± 1.29 kg) fitted with jugular cannula were randomly allocated to the SB and control (Con) groups, each group consisted of seven replicates (pens), with one pig per pen. At 9:00 of each day during the experimental period, pigs in the SB group were infused with 10 mL of SB (200 mmol/L, pH 7.4, 37 °C) via precaval vein, while the Con group was treated with the same volume of phys

Los estilos APA, Harvard, Vancouver, ISO, etc.

6

Fehér, Evelin, István Szatmári, Tamás Dudás, Anna Zalatnai, Tamás Farkas, Bálint Lőrinczi, Ferenc Fülöp, László Vécsei, and József Toldi. "Structural Evaluation and Electrophysiological Effects of Some Kynurenic Acid Analogs." Molecules 24, no. 19 (September 26, 2019): 3502. http://dx.doi.org/10.3390/molecules24193502.

Texto completo

Resumen

Kynurenic acid (KYNA), a metabolite of tryptophan, as an excitatory amino acid receptor antagonist is an effective neuroprotective agent in case of excitotoxicity, which is the hallmark of brain ischemia and several neurodegenerative processes. Therefore, kynurenine pathway, KYNA itself, and its derivatives came into the focus of research. During the past fifteen years, our research group has developed several neuroactive KYNA derivatives, some of which proved to be neuroprotective in preclinical studies. In this study, the synthesis of these KYNA derivatives and their evaluation with divergen

Los estilos APA, Harvard, Vancouver, ISO, etc.

7

Yan, Xi Ming, Ming Ruo Ding, Ming Guo Liu, Jun Zhi Wang, and Nian Yu Huang. "Study on Biomaterials of Anti-Gastric Trametenolic Acid B Semi-Synthetic Derivatives." Advanced Materials Research 918 (April 2014): 32–35. http://dx.doi.org/10.4028/www.scientific.net/amr.918.32.

Texto completo

Resumen

Discovery of bioactive ingredients from plants and fungi is always the hot spots in medicinal chemistry. The trametenolic acid B was a bioactive lanostane-type triterpenoid inTrametes lactinea(Berk.) Pat. In this work, four semi-synthetic derivatives were synthesized, characterized and evaluated the anti-gastric cancer activities against HGC-27 cells with the aim of obtaining better anti-tumor agents. The compounds2aand3bpossessed good anti-proliferative effects under normal physiological conditions, and their anti-cancer effects increased as the pH decrease to 5.5 with the IC50of 17.55 and 10

Los estilos APA, Harvard, Vancouver, ISO, etc.

8

Lupini, Antonio, Agostino Sorgonà, Maria Polsia Princi, Francesco Sunseri, and Maria Rosa Abenavoli. "Morphological and physiological effects of trans-cinnamic acid and its hydroxylated derivatives on maize root types." Plant Growth Regulation 78, no. 2 (June 17, 2015): 263–73. http://dx.doi.org/10.1007/s10725-015-0091-5.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

9

Sugiyama, Hironori, Seiichi Matsugo, Tetsuya Konishi, Toshinari Takamura, Shuichi Kaneko, Yukari Kubo, Kyouhei Sato, and Kan Kanamori. "Synthesis, Structure, and Physiological Effects of Peroxovanadium(V) Complexes Containing Amino Acid Derivatives as Ancillary Ligands." Chemistry Letters 41, no. 4 (April 5, 2012): 377–79. http://dx.doi.org/10.1246/cl.2012.377.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

10

Hoa, Nguyen Thi, Le Thi Ngoc Van, and Quan V. Vo. "The hydroperoxyl antiradical activity of natural hydroxycinnamic acid derivatives in physiological environments: the effects of pH values on rate constants." RSC Advances 12, no. 24 (2022): 15115–22. http://dx.doi.org/10.1039/d2ra02311c.

Texto completo

Los estilos APA, Harvard, Vancouver, ISO, etc.

11

Fotinos, Nicolas, Maruska Convert, Jean-Claude Piffaretti, Robert Gurny, and Norbert Lange. "Effects on Gram-Negative and Gram-Positive Bacteria Mediated by 5-Aminolevulinic Acid and 5-Aminolevulinic Acid Derivatives." Antimicrobial Agents and Chemotherapy 52, no. 4 (January 14, 2008): 1366–73. http://dx.doi.org/10.1128/aac.01372-07.

Texto completo

Resumen

ABSTRACT Due mainly to the extensive use of antibiotics, the spread of multiresistant bacterial strains is one of the most worrying threats to public health. One strategy that can be used to overcome potential shortcomings might be the inactivation of these microorganisms by 5-aminolevulinic acid (5-ALA) or 5-ALA derivative-mediated photodynamic therapy (PDT). 5-ALA has no photoactive properties, but when it is given exogenously, it acts as a precursor of photosensitive porphyrins predominantly in tissues or organisms that are characterized by a high metabolic turnover, such as tumors, macroph

Los estilos APA, Harvard, Vancouver, ISO, etc.

12

Angeli, Andrea, Victor Kartsev, Anthi Petrou, Mariana Pinteala, Roman M. Vydzhak, Svitlana Y. Panchishin, Volodymyr Brovarets, et al. "New Sulfanilamide Derivatives Incorporating Heterocyclic Carboxamide Moieties as Carbonic Anhydrase Inhibitors." Pharmaceuticals 14, no. 8 (August 23, 2021): 828. http://dx.doi.org/10.3390/ph14080828.

Texto completo

Resumen

Carbonic Anhydrases (CAs) are ubiquitous metalloenzymes involved in several disease conditions. There are 15 human CA (hCA) isoforms and their high homology represents a challenge for the discovery of potential drugs devoid of off-target side effects. For this reason, many synthetic and pharmacologic research efforts are underway to achieve the full pharmacological potential of CA modulators of activity. We report here a novel series of sulfanilamide derivatives containing heterocyclic carboxamide moieties which were evaluated as CA inhibitors against the physiological relevant isoforms hCA I,

Los estilos APA, Harvard, Vancouver, ISO, etc.

13

Al Mijan, Mohammad, Woo-Jin Sim, and Tae-Gyu Lim. "Physiological Effects of Green-Colored Food-Derived Bioactive Compounds on Cancer." Applied Sciences 11, no. 23 (November 29, 2021): 11288. http://dx.doi.org/10.3390/app112311288.

Texto completo

Resumen

Green-colored foods, such as broccoli, sprouts, soybean, and green leafy vegetables are considered one of the representative healthy foods for containing various functional ingredients that can combat chronic diseases, including diabetes, obesity, and cancer. Herein, we reviewed the anti-cancer activities and the underlying mechanisms of some important bioactive compounds, such as sulforaphane, catechins, chlorophyll, isoflavone, indole dervatives, and lutein, present in green-colored foods. In vivo and clinical studies suggest that sulforaphane, a sulfur-containing compound found in crucifero

Los estilos APA, Harvard, Vancouver, ISO, etc.

14

Małodobra-Mazur, Małgorzata, Dominika Lewoń, Aneta Cierzniak, Marta Okulus, and Anna Gliszczyńska. "Phospholipid Derivatives of Cinnamic Acid Restore Insulin Sensitivity in Insulin Resistance in 3T3-L1 Adipocytes." Nutrients 13, no. 10 (October 15, 2021): 3619. http://dx.doi.org/10.3390/nu13103619.

Texto completo

Resumen

Background: Insulin resistance (IR) is a condition in which the physiological amount of insulin is insufficient to evoke a proper response of the cell, that is, glucose utilization. Metformin is the first choice for therapy, thanks to its glycemic efficacy and general tolerability. In addition, various natural compounds from plant extracts, spices, and essential oils have been shown to provide health benefits regarding insulin sensitivity. In the present study, we analyzed the effect of phospholipid derivatives of selected natural aromatic acids on insulin action and their potential use to ove

Los estilos APA, Harvard, Vancouver, ISO, etc.

15

Ali, Md Sarafat, and Kwang-Hyun Baek. "Jasmonic Acid Signaling Pathway in Response to Abiotic Stresses in Plants." International Journal of Molecular Sciences 21, no. 2 (January 17, 2020): 621. http://dx.doi.org/10.3390/ijms21020621.

Texto completo

Resumen

Plants as immovable organisms sense the stressors in their environment and respond to them by means of dedicated stress response pathways. In response to stress, jasmonates (jasmonic acid, its precursors and derivatives), a class of polyunsaturated fatty acid-derived phytohormones, play crucial roles in several biotic and abiotic stresses. As the major immunity hormone, jasmonates participate in numerous signal transduction pathways, including those of gene networks, regulatory proteins, signaling intermediates, and proteins, enzymes, and molecules that act to protect cells from the toxic effe

Los estilos APA, Harvard, Vancouver, ISO, etc.

16

Bayer, Ilker S. "Hyaluronic Acid and Controlled Release: A Review." Molecules 25, no. 11 (June 6, 2020): 2649. http://dx.doi.org/10.3390/molecules25112649.

Texto completo

Resumen

Hyaluronic acid (HA) also known as hyaluronan, is a natural polysaccharide—an anionic, non-sulfated glycosaminoglycan—commonly found in our bodies. It occurs in the highest concentrations in the eyes and joints. Today HA is used during certain eye surgeries and in the treatment of dry eye disease. It is a remarkable natural lubricant that can be injected into the knee for patients with knee osteoarthritis. HA has also excellent gelling properties due to its capability to bind water very quickly. As such, it is one the most attractive controlled drug release matrices and as such, it is frequent

Los estilos APA, Harvard, Vancouver, ISO, etc.

17

Lin, Wei-Jiun, Han-Chen Ho, Sheng-Chang Chu, and Jui-Yu Chou. "Effects of auxin derivatives on phenotypic plasticity and stress tolerance in five species of the green alga Desmodesmus (Chlorophyceae, Chlorophyta)." PeerJ 8 (March 9, 2020): e8623. http://dx.doi.org/10.7717/peerj.8623.

Texto completo

Resumen

Green microalgae of the genus Desmodesmus are characterized by a high degree of phenotypic plasticity (i.e. colony morphology), allowing them to be truly cosmopolitan and withstand environmental fluctuations. This flexibility enables Desmodesmus to produce a phenotype–environment match across a range of environments broader compared to algae with more fixed phenotypes. Indoles and their derivatives are a well-known crucial class of heterocyclic compounds and are widespread in different species of plants, animals, and microorganisms. Indole-3-acetic acid (IAA) is the most common, naturally occu

Los estilos APA, Harvard, Vancouver, ISO, etc.

18

Maru, J. J., G. R. Patel, and Rakesh Yadav. "Spectral and Microbial Studies of some Newly Synthesized Schiff Base Derivatives of 2-(1H-Benzo[d]Oxazole-2-ylthio)-N-(4-Acetylphenyl)Acetamide." International Letters of Chemistry, Physics and Astronomy 44 (January 14, 2015): 57–65. http://dx.doi.org/10.56431/p-6c3m08.

Texto completo

Resumen

The author has synthesized novel biological active compounds by condensation of N-(4-Acetyl-phenyl)-2-(benzooxazol-2-ylsulfanyl)-acetamide with defferent substituted of acid hydrazide in the presence of catalytic amount of acetic acid. A series of benzoxazole having azomethine group were confirmed by various spectroscopic techniques. The new compounds were examined for antibacterial effects again different strain of bacteria and antifungal were high to lowest Minimum Inhibition Concentration (MIC) values.

Los estilos APA, Harvard, Vancouver, ISO, etc.

19

Avcu, Ferit, Burak Cem Soner, Oguzhan Yildiz, Kamile Ozturk, Pinar Elci, Meral Sarper, and Ali Ugur Ural. "EFFECTS of Zoledronic ACID On eNOS Exppression and Vascular Contractility IN Rat Aorta." Blood 116, no. 21 (November 19, 2010): 4318. http://dx.doi.org/10.1182/blood.v116.21.4318.4318.

Texto completo

Resumen

Abstract Abstract 4318 Zoledronic acid (ZOL) is a potent nitrogen-containing bisphosphonate used in the treatment of skeletal metabolic disorders and bone metastatic diseases. It has been shown that the nitrogenous bisphosphonates inhibits enzymes of mevalonate pathway. Similar with statin derivatives, ZOL affects the biological activity of geranyl-geranylated proteins in mevalonate pathway, as shown for the small GTPase RhoA. Although, beneficial effects of statin derivatives on vascular tissue have been reported, there is no study on effects and of ZOL on endothelial functions in vascular ti

Los estilos APA, Harvard, Vancouver, ISO, etc.

20

Del Buono, Daniele, Francesca Luzi, and Debora Puglia. "Lignin Nanoparticles: A Promising Tool to Improve Maize Physiological, Biochemical, and Chemical Traits." Nanomaterials 11, no. 4 (March 26, 2021): 846. http://dx.doi.org/10.3390/nano11040846.

Texto completo

Resumen

Lignin, and its derivatives, are the subject of current research for the exciting properties shown by this biomass. Particularly attractive are lignin nanoparticles for their eco- and biocompatibility compared to other nanomaterials. In this context, the effect of nanostructured lignin microparticles (LNP), obtained from alkaline lignin by acid treatment, on maize plants was investigated. To this end, maize seeds were primed with LNP at five concentrations: 80 mg L−1 (T80), 312 mg L−1 (T312), 1250 mg L−1 (T1250), 5000 mg L−1 (T5000) and 20,000 mg L−1 (T20000). Concerning the dose applied, LNP

Los estilos APA, Harvard, Vancouver, ISO, etc.

21

El-Nagar, Asmaa, Abdelnaser A. Elzaawely, Naglaa A. Taha, and Yasser Nehela. "The Antifungal Activity of Gallic Acid and Its Derivatives against Alternaria solani, the Causal Agent of Tomato Early Blight." Agronomy 10, no. 9 (September 16, 2020): 1402. http://dx.doi.org/10.3390/agronomy10091402.

Texto completo

Resumen

Tomato (Solanum lycopersicum L.) is among the most important vegetable crops worldwide. Early blight disease, caused by Alternaria solani, is a destructive foliar disease of tomato and other Solanaceae species. Herein, we investigated the in vitro antifungal properties of gallic acid and two of its derivatives (syringic and pyrogallic acids) against A. solani during 2019 and 2020 seasons. The physiological and biochemical effects of these compounds on infected tomato plants were also investigated using the whole plant bioassay. The in vitro investigation showed that all tested compounds showed

Los estilos APA, Harvard, Vancouver, ISO, etc.

22

Khalaf, Reema Abu, Ghassan Abu Sheikha, Mahmoud Al-Sha'er, and Mutasem Taha. "Design, Synthesis and Biological Evaluation of N4-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors." Open Medicinal Chemistry Journal 7, no. 1 (November 29, 2013): 39–48. http://dx.doi.org/10.2174/1874104501307010039.

Texto completo

Resumen

As incidence rate of type II diabetes mellitus continues to rise, there is a growing need to identify novel therapeutic agents with improved efficacy and reduced side effects. Dipeptidyl peptidase IV (DPP IV) is a multifunctional protein involved in many physiological processes. It deactivates the natural hypoglycemic incretin hormone effect. Inhibition of this enzyme increases endogenous incretin level, incretin activity and should restore glucose homeostasis in type II diabetic patients making it an attractive target for the development of new antidiabetic drugs. One of the interesting repor

Los estilos APA, Harvard, Vancouver, ISO, etc.

23

Villacorta, Luis, Francisco J. Schopfer, Jifeng Zhang, Bruce A. Freeman та Y. Eugene Chen. "PPARγ and its ligands: therapeutic implications in cardiovascular disease". Clinical Science 116, № 3 (8 січня 2009): 205–18. http://dx.doi.org/10.1042/cs20080195.

Texto completo

Resumen

The relevance of PPARγ (peroxisome-proliferator-activated receptor γ) as an important therapeutic target for the treatment of diabetes arises from its hypoglycaemic effects in diabetic patients and also from the critical role in the regulation of cardiovascular functions. From a clinical perspective, differences between current FDA (Food and Drug Administration)-approved PPARγ drugs have been observed in terms of atherosclerosis and cardiac and stroke events. The adverse effects of PPARγ-specific treatments that hamper their cardiovascular protective roles, affirm the strong need to evaluate t

Los estilos APA, Harvard, Vancouver, ISO, etc.

24

Szelest, Monika, Katarzyna Walczak, and Tomasz Plech. "A New Insight into the Potential Role of Tryptophan-Derived AhR Ligands in Skin Physiological and Pathological Processes." International Journal of Molecular Sciences 22, no. 3 (January 22, 2021): 1104. http://dx.doi.org/10.3390/ijms22031104.

Texto completo

Resumen

The aryl hydrocarbon receptor (AhR) plays a crucial role in environmental responses and xenobiotic metabolism, as it controls the transcription profiles of several genes in a ligand-specific and cell-type-specific manner. Various barrier tissues, including skin, display the expression of AhR. Recent studies revealed multiple roles of AhR in skin physiology and disease, including melanogenesis, inflammation and cancer. Tryptophan metabolites are distinguished among the groups of natural and synthetic AhR ligands, and these include kynurenine, kynurenic acid and 6-formylindolo[3,2-b]carbazole (F

Los estilos APA, Harvard, Vancouver, ISO, etc.

25

Reang, Jurnal, Prabodh Chander Sharma, Vijay Kumar Thakur, and Jaseela Majeed. "Understanding the Therapeutic Potential of Ascorbic Acid in the Battle to Overcome Cancer." Biomolecules 11, no. 8 (July 31, 2021): 1130. http://dx.doi.org/10.3390/biom11081130.

Texto completo

Resumen

Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various developments to prevent and treat cancer, the side effects of anticancer drugs remain a major concern. Ascorbic acid is an essential vitamin required by our bodies for normal physiological function and also has antioxidant and anticancer activity. Although the body cannot synthesize ascorbic acid, it is abundant in nature through foods and other natural sources and also exists as a nutritional food supplement. In anticancer drug development, ascorbic acid has played an important role by inhibiting the d

Los estilos APA, Harvard, Vancouver, ISO, etc.

26

Salachna, Piotr, and Anna Pietrak. "Evaluation of Carrageenan, Xanthan Gum and Depolymerized Chitosan Based Coatings for Pineapple Lily Plant Production." Horticulturae 7, no. 2 (January 29, 2021): 19. http://dx.doi.org/10.3390/horticulturae7020019.

Texto completo

Resumen

Some natural polysaccharides and their derivatives are used in horticulture to stimulate plant growth. This study investigated the effects of coating bulbs with carrageenan-depolymerized chitosan (C-DCh) or xanthan-depolymerized chitosan (X-DCh) on growth, flowering, and bulb yield as well as physiological and biochemical attributes of pineapple lily (Eucomis autumnalis). The results showed that treatment with C-DCh or X-DCh significantly increased all growth parameters, bulb yield, greenness index, stomatal conductance, total N, total K, and total sugar content of bulbs and accelerated anthes

Los estilos APA, Harvard, Vancouver, ISO, etc.

27

Ramabulana, Anza-Tshilidzi, Paul A. Steenkamp, Ntakadzeni E. Madala, and Ian A. Dubery. "Profiling of Altered Metabolomic States in Bidens pilosa Leaves in Response to Treatment by Methyl Jasmonate and Methyl Salicylate." Plants 9, no. 10 (September 27, 2020): 1275. http://dx.doi.org/10.3390/plants9101275.

Texto completo

Resumen

Bidens pilosa (Asteraceae) is an edible medicinal plant with many bioactivities reported to have a health-beneficial role in controling various diseases. Though B. pilosa contain a diverse array of natural products, these are produced in relatively low concentrations. A possible way to enhance secondary metabolite production can be through the use of elicitors. Here, the effects of exogenous treatments with two signal molecules—methyl jasmonate (MeJA) and methyl salicylate (MeSA)—on the metabolomic profiles of B. pilosa leaves were investigated. Plants were treated with 0.5 mM of MeJA or MeSA

Los estilos APA, Harvard, Vancouver, ISO, etc.

28

Katagi, Manjunatha S., Jennifer Fernandes, Shivalingrao Mamledesai, Sujatha M.L., Rekha A., and Girish Bolakatti. "Schiff Base Oxime Derivatives Reactivate Chlorpyrifos-induced Acetylcholinesterase Inhibition." INNOSC Theranostics and Pharmacological Sciences 2, no. 1 (July 2, 2019): 12–16. http://dx.doi.org/10.26689/itps.v2i1.499.

Texto completo

Resumen

Background: The biological effects of organophosphorus (OP) compounds are connected with the irreversible inhibition of acetylcholinesterase (AChE), an important neuromediator acetylcholine (ACh) splitting enzyme in the human body at the synaptic clefts. Due to this inhibition, AChE is unable to fulfil its physiological function resulting in the accumulation of ACh, which, in turn over stimulates the parasympathetic nerve receptors, and causes fatal cholinergic crisis. Objective: The objective of the study was to synthesize a series of Schiff base oximes and to assess their evaluating fo

Los estilos APA, Harvard, Vancouver, ISO, etc.

29

Serreli, Gabriele, Micaela Rita Naitza, Sonia Zodio, Vera Piera Leoni, Martina Spada, Maria Paola Melis, Anna Boronat, and Monica Deiana. "Ferulic Acid Metabolites Attenuate LPS-Induced Inflammatory Response in Enterocyte-like Cells." Nutrients 13, no. 9 (September 10, 2021): 3152. http://dx.doi.org/10.3390/nu13093152.

Texto completo

Resumen

Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in numerous foods of a plant origin. Its dietary consumption leads to the formation of several phase I and II metabolites in vivo, which represent the largest amount of ferulates in the circulation and in the intestine in comparison with FA itself. In this work, we evaluated their efficacy against the proinflammatory effects induced by lipopolysaccharide (LPS) in intestinal Caco-2 cell monolayers, as well as the mechanisms underlying their protective action. LPS-induced overexpression of proinflammatory

Los estilos APA, Harvard, Vancouver, ISO, etc.

30

Holeček, Milan. "Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement." Nutrients 12, no. 3 (March 22, 2020): 848. http://dx.doi.org/10.3390/nu12030848.

Texto completo

Resumen

L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the histaminergic system. Several HIS-rich proteins (e.g., haemoproteins, HIS-rich glycoproteins, histatins, HIS-rich calcium-binding protein, and filaggrin), HIS-containing dipeptides (particularly carnosine), and methyl- and sulphur-containing derivatives of HIS (3-methylhistidine, 1-methylhistidine, and ergothioneine) have specific functions. The unique chemical properties and physiological functions are the basis of

Los estilos APA, Harvard, Vancouver, ISO, etc.

31

Srovnalova, Alzbeta, Sona Gurska, Milan Urban, Jan Sarek, Jiri Rehulka, Petr Dzubak, and Marian Hajduch. "Abstract 1530: Derivatives of betulinic acid act as modulators of the androgen receptor and report cytotoxicity towards cancer cell lines." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1530. http://dx.doi.org/10.1158/1538-7445.am2022-1530.

Texto completo

Resumen

Abstract INTRODUCTION Triterpenoids are naturally occurring substances with a broad spectrum of beneficial effects for human health. Betulinic acid belongs to the group of pentacyclic triterpenoids and is well known for its antitumor activities. The library of about 1000 betulinic acid-derived triterpenes was collected and analyzed for cytotoxic activity on cancer and non-cancer cell lines (A549, CCRF-CEM, CEM-DNR, HCT116, K562, K562-TAX, U2OS, BJ and MRC-5) in our Institute over the last 20 years. Steroidal triterpenes are precursors of cholesterol, the precursor of testosterone, the fundamen

Los estilos APA, Harvard, Vancouver, ISO, etc.

32

Ferrari, Nicoletta, Magnus Pfahl та Giovanni Levi. "Retinoic Acid Receptor γ1 (RARγ1) Levels Control RARβ2 Expression in SK-N-BE2(c) Neuroblastoma Cells and Regulate a Differentiation-Apoptosis Switch". Molecular and Cellular Biology 18, № 11 (1 листопада 1998): 6482–92. http://dx.doi.org/10.1128/mcb.18.11.6482.

Texto completo

Resumen

ABSTRACT Vitamin A and its derivatives (retinoids) have profound effects on the proliferation and differentiation of many cell types and are involved in a diverse array of developmental and physiological regulatory processes, including those responsible for the development of the mature nervous system. Retinoid signals are mediated by retinoic acid (RA) receptors (RARs) and retinoid X receptors (RXRs), which show distinct spatio-temporal patterns of expression during development and in adult tissues. We have used SK-N-BE2(c) neuroblastoma cells to study the effects of reciprocal regulation of

Los estilos APA, Harvard, Vancouver, ISO, etc.

33

Arróniz-Crespo, María, Encarnación Núñez-Olivera, Javier Martínez-Abaigar, Hans Becker, Jochen Scher, Josef Zapp, Rafael Tomás, and Nathalie Beaucourt. "Physiological changes and UV protection in the aquatic liverwort Jungermannia exsertifolia subsp. cordifolia along an altitudinal gradient of UV-B radiation." Functional Plant Biology 33, no. 11 (2006): 1025. http://dx.doi.org/10.1071/fp06096.

Texto completo

Resumen

Here we report the effects of a natural altitudinal gradient of UV-B radiation, from 1140 to 1816 m altitude, on the physiology of the aquatic liverwort Jungermannia exsertifolia Steph. subsp. cordifolia (Dumort.) Váña collected in mountain streams. Photosynthetic pigments, net photosynthesis and dark respiration rates, chlorophyll fluorescence, protein concentration, sclerophylly, and UV-absorbing compounds [both global UV absorbance of methanol-extractable UV-absorbing compounds (MEUVAC) and concentrations of five individual compounds] were measured. Two new caffeic acid derivatives were dis

Los estilos APA, Harvard, Vancouver, ISO, etc.

34

Li, Tong, Ruiguo Wang, and Peilong Wang. "The Development of an Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry Method for Biogenic Amines in Fish Samples." Molecules 28, no. 1 (December 26, 2022): 184. http://dx.doi.org/10.3390/molecules28010184.

Texto completo

Resumen

Biogenic amines (BAs) are a group of substances that are formed from amino acids by decarboxylation or amination and transamination of aldehydes and ketones. They may have either an aliphatic, aromatic, or heterocyclic structure. Their quantity determines their effects and optimum amounts are essential for physiological functions, but excess BAs causes various toxic effects throughout the human body. In our study, to rapidly determine 14 BAs (histamine, tyramine, dopamine, tryptamine, serotonin, putrescine, spermine, spermidine, octopamine, benzylamine, 1-Phenylethanamine, cadaverine, 2-Phenet

Los estilos APA, Harvard, Vancouver, ISO, etc.

35

Krzyżanowska-Kowalczyk, Justyna, Mariusz Kowalczyk, Michał B. Ponczek, Łukasz Pecio, Paweł Nowak, and Joanna Kolodziejczyk-Czepas. "Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors–In Vitro and In Silico Studies." Molecules 26, no. 3 (January 26, 2021): 631. http://dx.doi.org/10.3390/molecules26030631.

Texto completo

Resumen

The Pulmonaria species (lungwort) are edible plants and traditional remedies for different disorders of the respiratory system. Our work covers a comparative study on biological actions in human blood plasma and cyclooxygenase-2 (COX-2) -inhibitory properties of plant extracts (i.e., phenolic-rich fractions) originated from aerial parts of P. obscura Dumort. and P. officinalis L. Phytochemical profiling demonstrated the abundance of phenolic acids and their derivatives (over 80% of the isolated fractions). Danshensu conjugates with caffeic acid, i.e., rosmarinic, lithospermic, salvianolic, mon

Los estilos APA, Harvard, Vancouver, ISO, etc.

36

Chuyan, E. N., I. S. Mironyuk, M. Yu Ravaeva, T. V. Grishina, I. V. Cheretaev, and S. E. Chernobai. "Changes in micro- and central hemodynamic parameters in rats under the action of acetylsalicylic acid and its coordination compounds with metals." Regional blood circulation and microcirculation 20, no. 4 (January 10, 2022): 75–86. http://dx.doi.org/10.24884/1682-6655-2021-20-4-75-86.

Texto completo

Resumen

Introduction. The cutaneous blood circulation is a representative model both for studying the mechanisms of vascular diseases and for assessing the current state of the central hemodynamics in preclinical researches of various chemical compounds. Aim. The changes in the parameters of cutaneous microcirculation and central hemodynamics (heart rate and blood pressure) were studied in the animals under the action of acetylsalicylic acid and its coordination compounds with cations of cobalt, zinc, nickel and manganese at a dose of 20 mg/kg. Materials and methods. The research was conducted using t

Los estilos APA, Harvard, Vancouver, ISO, etc.

37

Jiang, Ni-Hao, and Shi-Han Zhang. "Effects of Combined Application of Potassium Silicate and Salicylic Acid on the Defense Response of Hydroponically Grown Tomato Plants to Ralstonia solanacearum Infection." Sustainability 13, no. 7 (March 27, 2021): 3750. http://dx.doi.org/10.3390/su13073750.

Texto completo

Resumen

Bacterial wilt, caused by soilborne pathogenic bacterium Ralstonia solanacearum, is a serious and widespread disease that affects global tomato production. Both silicon (Si) and salicylic acid (SA) play important roles in enhancing tomato resistance against bacterial wilt, however, their combined effects on the defense responses of infected tomato plants remain unknown. Hence, the combined effects of Si and SA on physiological and biochemical parameters of R. solanacearum-infected tomato plants were investigated. The combination treatment of Si and SA significantly decreased disease incidences

Los estilos APA, Harvard, Vancouver, ISO, etc.

38

Dougkas, Anestis, Christopher K. Reynolds, Ian D. Givens, Peter C. Elwood, and Anne M. Minihane. "Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms." Nutrition Research Reviews 24, no. 1 (February 15, 2011): 72–95. http://dx.doi.org/10.1017/s095442241000034x.

Texto completo

Resumen

As the incidence of obesity is reaching ‘epidemic’ proportions, there is currently widespread interest in the impact of dietary components on body-weight and food intake regulation. The majority of data available from both epidemiological and intervention studies provide evidence of a negative but modest association between milk and dairy product consumption and BMI and other measures of adiposity, with indications that higher intakes result in increased weight loss and lean tissue maintenance during energy restriction. The purported physiological and molecular mechanisms underlying the impact

Los estilos APA, Harvard, Vancouver, ISO, etc.

39

Liang, Xin, Ruyi Qian, Dan Wang, Lijuan Liu, Chengliang Sun, and Xianyong Lin. "Lipid-Derived Aldehydes: New Key Mediators of Plant Growth and Stress Responses." Biology 11, no. 11 (October 29, 2022): 1590. http://dx.doi.org/10.3390/biology11111590.

Texto completo

Resumen

Aldehydes, derivatives of lipids, are ubiquitously produced through non-enzymatic and enzymatic pathways in higher plants and participate in many physiological and biological processes. Increasing evidence demonstrates that aldehydes are involved in plants response to many abiotic stresses, such as light, drought, heat and nutrient deficiency. In plant cells, endogenously triggered or exogenously applied high concentrations of aldehydes can damage proteins and nucleic acid, disturb redox homeostasis, and consequently inhibit plant growth; therefore, they are considered cytotoxins. Aldehyde lev

Los estilos APA, Harvard, Vancouver, ISO, etc.

40

Hussain, M., Manuel Reigosa та Adele Muscolo. "Carbon (δ13C) and Nitrogen (δ15N) Stable Isotope Composition Provide New Insights into Phenotypic Plasticity in Broad Leaf Weed Rumex acetosa under Allelochemical Stress". Molecules 23, № 10 (25 вересня 2018): 2449. http://dx.doi.org/10.3390/molecules23102449.

Texto completo

Resumen

Phenolic compounds, hydroquinone and cinnamic acid derivatives have been identified as major allelochemicals with known phytotoxicity from allelopathic plant Acacia melanoxylon R. Br. Several phenolic compounds such as ferulic acid (FA), p-hydroxybenzoic acid (pHBA) and flavonoid (rutin, quercetin) constituents occur in the phyllodes and flowers of A. melanoxylon and have demonstrated inhibitory effects on germination and physiological characteristics of lettuce and perennial grasses. However, to date, little is known about the mechanisms of action of these secondary metabolites in broad-leave

Los estilos APA, Harvard, Vancouver, ISO, etc.

41

Steinhardt, M., and H. H. Thielscher. "Wachstum und Entwicklungsqualität von Milchrindkälbern in Gruppenhaltung mit Tränkeautomatenfütterung. Physiologische Variablen und deren Änderungen in spezifischen Altersperioden." Archives Animal Breeding 43, no. 1 (October 10, 2000): 27–44. http://dx.doi.org/10.5194/aab-43-27-2000.

Texto completo

Resumen

Abstract. Title of the paper: Growth and development quality of dairy calves reared in groups with an automatic milk feeder. Physiological variables and their changes at specific age periods On 38 dairy calves (20 male, 18 female) measurements of growth Performance and of body temperature (RT) and blood sampling were made at 15, 30, 60 and 90 days of age of the calves. Blood was analysed for acid-base balance, biochemical and hematological values, minerals and hemoglobin derivatives. Effects of season (groupl: calvings from October tili December; group 2: calvings from January tili April) and

Los estilos APA, Harvard, Vancouver, ISO, etc.

42

Petreska, Jasmina, Gjose Stefkov, Svetlana Kulevanova, Kalina Alipieva, Vassya Bankova, and Marina Stefova. "Phenolic Compounds of Mountain Tea from the Balkans: LC/DAD/ESI/MSn Profile and Content." Natural Product Communications 6, no. 1 (January 2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600107.

Texto completo

Resumen

Twenty-one samples of Sideritis species ( S. scardica, S. raeseri, S. taurica, S. syriaca and S. perfoliata) from various locations on the Balkan Peninsula were evaluated for their chemical constituents. Chemical analyses were focused on secondary metabolites, particularly phenolic compounds, which have several roles in the plant physiological processes and have demonstrated significant health beneficial effects. The occurrence of hydroxycinnamic acids, phenylethanoid glycosides and flavonoids has been investigated in taxonomically related taxa of the genus Sideritis. A systematic method for p

Los estilos APA, Harvard, Vancouver, ISO, etc.

43

Wang, Yanyan, Yang Wang, Hefei Bai, Yuqian Han, and Fang Yu. "An ABCG-Type Transporter Facilitates ABA Influx and Regulates Camptothecin Biosynthesis in Camptotheca acuminata." International Journal of Molecular Sciences 23, no. 24 (December 17, 2022): 16120. http://dx.doi.org/10.3390/ijms232416120.

Texto completo

Resumen

Camptothecin (CPT) and its derivatives from Camptotheca acuminata have antitumor effects as a DNA topoisomerase I inhibitor. Previous studies have shown that application of exogenous abscisic acid (ABA) significantly promoted the accumulation level of CPT and induced the expression of CPT biosynthetic genes, which revealed that ABA signaling is effectively involved in regulating CPT biosynthesis in C. acuminata. In this study, an ABA transporter, CaABAT, which encodes a plasma membrane protein belonging to the ABCG subfamily, was identified in C. acuminata, and its ABA import activity was conf

Los estilos APA, Harvard, Vancouver, ISO, etc.

44

Karkischenko, N. N., V. N. Karkischenko, Yu V. Fokin, L. A. Taboyakova, O. V. Alimkina, and M. M. Borisova. "Between Cognitivity and Neuropathies: Neuroimaging of the Effects of GABAergic Modulation of the Hippocampus and Prefrontal Neocortexis by Normalized Brain Electrograms." Journal Biomed, no. 2 (June 10, 2020): 12–38. http://dx.doi.org/10.33647/2074-5982-16-2-12-38.

Texto completo

Resumen

A comparative analysis conducted across the entire range of normalized brain electrograms (NBE) revealed the selective effect of gamma-aminobutyric acid (GABA) derivatives in the hippocampus and frontal pole of the neocortex. A signifi cant similarity in the level of activation of these brain regions was revealed under the action of glutamine and, particularly, gabapentin. For gabapentin, the activity of the hippocampus is more comparable to that in the anterior suprasilvius gyrus. Under the action of pregabalin, NBE revealed a similarity between the hippocampus and the proreal gyrus, with a m

Los estilos APA, Harvard, Vancouver, ISO, etc.

45

Shen, Changchao, Wenwei Tang, Dongqiang Zeng, Hongle Xu, Wangcang Su, and Renhai Wu. "Isoxadifen-Ethyl Derivatives Protect Rice from Fenoxaprop-P-Ethyl–associated Injury during the Control of Weedy Rice." Weed Science 65, no. 5 (August 2, 2017): 579–87. http://dx.doi.org/10.1017/wsc.2017.27.

Texto completo

Resumen

Fenoxaprop-P-ethyl, a phenoxy herbicide of the aryloxy–phenoxy–propionic acid group, had a strong control effect when applied POST to weedy rice in this study, with the effective concentrations of 294 μM and 218 μM of herbicide causing 50% inhibition (IC50) in plant height and fresh weight values, respectively. However, fenoxaprop-P-ethyl caused phytotoxicity in cultivated rice. Isoxadifen-ethyl, a widely used herbicide safener in rice, can decrease the phytotoxicity caused by fenoxaprop-P-ethyl. Owing to the extremely similar morphological features and physiological properties of weedy and cu

Los estilos APA, Harvard, Vancouver, ISO, etc.

46

Okamoto, Lillian L., Caleb C. Reichhardt, Brian Griffin, Laura A. Smith, Gordon Murdoch, and Kara J. Thornton. "PSIX-28 Examining the effects of estradiol, trenbolone acetate, or polyamines on bovine satellite cell differentiation." Journal of Animal Science 98, Supplement_4 (November 3, 2020): 333. http://dx.doi.org/10.1093/jas/skaa278.592.

Texto completo

Resumen

Abstract The mechanism through which anabolic implants improve skeletal muscle growth of beef animals is incompletely understood. Polyamines (PA) are bioactive amino acid derivatives that act as potent growth stimulants. The objective of this study was to determine effects of anabolic implants, PA and their precursors on bovine satellite cell (BSC) differentiation. Primary BSC were cultured to approximately 80% confluency, at which time they were induced to differentiate in the presence of 3% horse serum (Con) and treated with 10nM TBA, 10 nM E2, or 10nM TBA and 10 nM E2 (ETBA), 10 mM methioni

Los estilos APA, Harvard, Vancouver, ISO, etc.

47

Ghias, Mehreen, Syed Wadood Ali Shah, Fakhria A. Al-Joufi, Mohammad Shoaib, Syed Muhammad Mukarram Shah, Muhammad Naeem Ahmed, and Muhammad Zahoor. "In Vivo Antistress Effects of Synthetic Flavonoids in Mice: Behavioral and Biochemical Approach." Molecules 27, no. 4 (February 18, 2022): 1402. http://dx.doi.org/10.3390/molecules27041402.

Texto completo

Resumen

Natural flavonoids, in addition to some of their synthetic derivatives, are recognized for their remarkable medicinal properties. The present study was designed to investigate the in vitro antioxidant and in vivo antistress effect of synthetic flavonoids (flavones and flavonols) in mice, where stress was induced by injecting acetic acid and physically through swimming immobilization. Among the synthesized flavones (F1–F6) and flavonols (OF1–OF6), the mono para substituted methoxy containing F3 and OF3 exhibited maximum scavenging potential against DPPH (2,2-diphenyl-1-picrylhydrazyl) with IC50

Los estilos APA, Harvard, Vancouver, ISO, etc.

48

Timoneda, Joaquín, Lucía Rodríguez-Fernández, Rosa Zaragozá, M. Marín, M. Cabezuelo, Luis Torres, Juan Viña, and Teresa Barber. "Vitamin A Deficiency and the Lung." Nutrients 10, no. 9 (August 21, 2018): 1132. http://dx.doi.org/10.3390/nu10091132.

Texto completo

Resumen

Vitamin A (all-trans-retinol) is a fat-soluble micronutrient which together with its natural derivatives and synthetic analogues constitutes the group of retinoids. They are involved in a wide range of physiological processes such as embryonic development, vision, immunity and cellular differentiation and proliferation. Retinoic acid (RA) is the main active form of vitamin A and multiple genes respond to RA signalling through transcriptional and non-transcriptional mechanisms. Vitamin A deficiency (VAD) is a remarkable public health problem. An adequate vitamin A intake is required in early lu

Los estilos APA, Harvard, Vancouver, ISO, etc.

49

Ramiro-Cortijo, David, Pratibha Singh, Yan Liu, Esli Medina-Morales, William Yakah, Steven D. Freedman, and Camilia R. Martin. "Breast Milk Lipids and Fatty Acids in Regulating Neonatal Intestinal Development and Protecting against Intestinal Injury." Nutrients 12, no. 2 (February 19, 2020): 534. http://dx.doi.org/10.3390/nu12020534.

Texto completo

Resumen

Human breast milk is the optimal source of nutrition for infant growth and development. Breast milk fats and their downstream derivatives of fatty acids and fatty acid-derived terminal mediators not only provide an energy source but also are important regulators of development, immune function, and metabolism. The composition of the lipids and fatty acids determines the nutritional and physicochemical properties of human milk fat. Essential fatty acids, including long-chain polyunsaturated fatty acids (LCPUFAs) and specialized pro-resolving mediators, are critical for growth, organogenesis, an

Los estilos APA, Harvard, Vancouver, ISO, etc.

50

Ren, Wei, Qian Wang, Li Chen, and Yanping Ren. "Transcriptome and Metabolome Analyses of Salt Stress Response in Cotton (Gossypium hirsutum) Seed Pretreated with NaCl." Agronomy 12, no. 8 (August 4, 2022): 1849. http://dx.doi.org/10.3390/agronomy12081849.

Texto completo

Resumen

Abiotic stresses adversely influence crop productivity and salt stress is one limiting factor. Plants need to evolve their defense mechanisms to survive in such fluctuating scenarios at either the biochemical, physiological, or molecular level. The analytical/critical investigations of cotton (Gossypium hirsutum) plants that involve looking into transcriptomic and metabolomic profiles could give a comprehensive picture of the response of the cotton plant to salt stress. This study was conducted on pre-treated cotton seeds by soaking them in a 3% sodium chloride (NaCl) solution at room temperat

Los estilos APA, Harvard, Vancouver, ISO, etc.

Ofrecemos descuentos en todos los planes premium para autores cuyas obras están incluidas en selecciones literarias temáticas. ¡Contáctenos para obtener un código promocional único!