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Tesis sobre el tema "Embryonic implantation"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 25 de julio de 2025

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1

Henderson, Janet Katharine. "Investigations of human embryonic implantation in vitro." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341905.

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2

Aghajanova, Lusine. "Endometrial, embryonic and ovarian aspects of human implantation /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-794-4/.

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3

Spikings, Emma Catherine. "Mitochondrial DNA replication in pre-implantation embryonic development." Thesis, University of Birmingham, 2007. http://etheses.bham.ac.uk//id/eprint/45/.

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All eukaryotic cells possess mitochondrial DNA (mtDNA), which is maternally inherited through the oocyte, its replication being regulated by nuclear-encoded replication factors. It was hypothesised that mtDNA replication is highly regulated in oocytes, pre-implantation embryos and embryonic stem cells (ESCs) and that this may be disrupted following nuclear transfer (NT). MtDNA copy number decreased between 2-cell and 8-cell staged porcine embryos and increased between the morula and expanded blastocyst stages, coinciding with increased expression of mtDNA replication factors. Competent porcine

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4

Thomas, Penelope S. "Patterns of protein synthesis in early post-implantation rat embryos." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253268.

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5

Pillai, Chitra Claire. "IGFPBp1 : a multifunctional role in implantation, embryonic and fetal development." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271064.

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6

Bagot, Catherine Nancy. "An investigation of the role of maternal hoxiao in embryonic implantation." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250192.

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7

Magaña, Griselda Valdez. "Crosstalk between embryonic and extraembyonic tissues in pre-implantation pig embryos." Thesis, University of Nottingham, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.662205.

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The coordinated growth of the conceptus is sustained by reciprocal signalling between the epiblast and the extraembryonic ectoderm (ExE). In mice, FGF4 produced by the epiblast promotes Cdx2 expression in the trophoblast stem cell (TSC) niche located in the ExE. Cdx2, Eomes and EIf-5 expression in the ExE constitute an auto-regulatory circuit that maintains the mouse TSC gene network. Cells in the ExE, in turn secrete BMP4, which is a critical mesoderm determinant. The ExE however, is absent in non-rodent embryos, raising the question whether the cross-talk between embryonic and extraembryonic

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8

Udayashankar, Ramya. "A model of trophoblast development and implantation using human embryonic stem cells." Thesis, University of Sheffield, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505349.

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Abnormal embryo implantation may lead to poor fetal development and miscarriage, or pre-eclampsia. Due to ethical and practical restrictions, and the morphological diversity of implantation in laboratory animals, it is important to develop new in vitro models to study early events of human implantation. The aim of this study was to derive trophoblast stem cell lines from human embryonic stem cells (hESCs) through an effective repeatable protocol and to co-culture these cells together with an established endometrial cell culture system to develop and validate a model to study the molecular even

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9

Cha, Jeeyeon. "The role of muscle segment homeobox genes in early pregnancy events." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1377871689.

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10

Huang, Tingting. "Characterization of the Visceral Endoderm Components in Early Post-Implantation Mouse Embryo Development: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/694.

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Early post-implantation vertebrate embryos are shaped by complex cellular and molecular mechanisms. In mice, the visceral endoderm, an extraembryonic cell lineage that appears before gastrulation, provides several important functions such as nutrition and mechanical protection. My thesis research focused on the role of the visceral endoderm in embryo patterning, a newly discovered function for this tissue. My results showed that an interplay between two subpopulations of visceral endoderm the anterior and posterior visceral endoderm, located on the opposite sides of the developing conceptus, a

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11

Huang, Tingting. "Characterization of the Visceral Endoderm Components in Early Post-Implantation Mouse Embryo Development: A Dissertation." eScholarship@UMMS, 2002. http://escholarship.umassmed.edu/gsbs_diss/694.

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Early post-implantation vertebrate embryos are shaped by complex cellular and molecular mechanisms. In mice, the visceral endoderm, an extraembryonic cell lineage that appears before gastrulation, provides several important functions such as nutrition and mechanical protection. My thesis research focused on the role of the visceral endoderm in embryo patterning, a newly discovered function for this tissue. My results showed that an interplay between two subpopulations of visceral endoderm the anterior and posterior visceral endoderm, located on the opposite sides of the developing conceptus, a

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12

Loof, Gesa. "Elucidating the influence of chromatin topology on cellular identity in murine pre-implantation development." Doctoral thesis, Humboldt-Universität zu Berlin, 2021. http://dx.doi.org/10.18452/22928.

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Präzise regulierte Genexpression, ist der Schlüssel zu erfolgreicher Embryonal-entwicklung. Die Expression von Zelltyp-spezifischen Transkriptionsfaktoren kann durch räumliche Interaktionen von Promotoren und Enhancern im Nukleus kontrolliert werden, aber auch durch 3D Faltung der DNA in größere organisatorische Einheiten wie “Topologically Associating Domains” (TADs) oder “A/B compartments”. Um die 3D Faltung in den Zelltypen des prä-implantations Embryos zu untersuchen, nutze ich ES und XEN Zellen, die stark dem Epiblast und dem primitiven Endoderm in der inneren Zellmasse des E4.5 Embryos

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13

Barblett, Hamish. "Factors affecting the survival and implantation of human blastocysts following vitrification." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2019. https://ro.ecu.edu.au/theses/2228.

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The increased cell numbers, presence of the blastocoel and rapid cell re-organisation have required the development of specific survival criteria post warm to effectively select the most viable blastocyst for transfer. Pre-freeze blastocyst expansion and post warm re-expansion have been shown to contribute significantly to the chances of an implantation and subsequent live birth. The aim of this study was to explore factors that influence the outcome of blastocyst transfers after vitrification and warming, and hopefully improve outcomes by further applying improvements in future cycles. Variab

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14

Douglas, Deborah Ann. "Luteotropic effects of prolactin on the mink, Mustela vison, ovary during embryonic diapause and early post-implantation gestation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0025/NQ29925.pdf.

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15

Douglas, Deborah Ann. "Luteotropic effects of prolactin on the mink (Mustela vison) ovary during embryonic diapause and early post-implantation gestation." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42020.

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These studies were conducted to determine the mechanisms by which prolactin (PRL) exerts its luteotropic effects on the mink corpus luteum (CL). Three experimental models were developed and utilized in these studies. In the first model, the ovaries from pregnant mink were collected at regular intervals throughout gestation, half the animals were treated with the dopamine agonist 2-bromo-$ alpha$-ergocryptine (bromocryptine), to suppress their endogenous PRL levels, and half were exposed to their endogenous PRL levels. The second model consisted of treating anestrous animals with exogenous gona

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16

Brimson, Christopher A. "The role of Hippo signalling in cell fate decisions in mouse embryonic stem cells and pre-implantation development." Thesis, University of Bath, 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687385.

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The Hippo signalling pathway is a conserved kinase cascade involved in the regulation of tissue growth and organ size. Activation of the Hippo pathway through multiple upstream inputs results in phosphorylation and inactivation of the transcriptional co-activator, Yes associated protein (Yap). While the role of Yap as an oncogene and an effector of the Hippo pathway is well established, its role in cellular differentiation is less well known. In this present work I have utilised quantitative immunofluorescence analysis to examine the expression of Yap in the differentiation of mouse embryonic

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17

Morrish, Paul K. "A clinical and [18F]dopa PET study of the progression of Parkinson's disease and its treatment by embryonic implantation." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361927.

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18

Guo, Jiami. "The requirement of Smad4 in Mouse Early Embryonic Development." Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1343160155.

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19

Flores, Landaverde Luis Eduardo [Verfasser]. "Early detection of embryonic post implantation failures by ultrasound biomicroscopy and the role of the maternal immune system / Luis Eduardo Flores Landaverde." Berlin : Freie Universität Berlin, 2017. http://d-nb.info/1148426302/34.

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20

Bloomfield, Kelly Louise, and n/a. "Investigation of the Role of Thioredoxin in the Invasive Phenotype and its Interaction with the Transcription Factor Sp1." Griffith University. School of Biomolecular and Biomedical Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20031021.120018.

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Thioredoxin is a small ubiquitous oxido-reductase found in all species. The highly conserved active site, which facilitates thioredoxins redox activity, contains two redox active cysteine residues. Thioredoxin has numerous protein substrates to which it donates H+ ions and it can also function as a free radical scavenger. Through these activities thioredoxin is able to influence the redox state of not only its protein targets, but also the entire cellular environment. Thioredoxin has been implicated in many biological functions, and one mechanism by which it influences these functions is t

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21

Bloomfield, Kelly Louise. "Investigation of the Role of Thioredoxin in the Invasive Phenotype and its Interaction with the Transcription Factor Sp1." Thesis, Griffith University, 2003. http://hdl.handle.net/10072/366170.

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Thioredoxin is a small ubiquitous oxido-reductase found in all species. The highly conserved active site, which facilitates thioredoxins redox activity, contains two redox active cysteine residues. Thioredoxin has numerous protein substrates to which it donates H+ ions and it can also function as a free radical scavenger. Through these activities thioredoxin is able to influence the redox state of not only its protein targets, but also the entire cellular environment. Thioredoxin has been implicated in many biological functions, and one mechanism by which it influences these functions is t

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22

Castro, Karla Ribeiro de. "Efeitos da exposição crônica à poluição atmosférica urbana sobre a receptividade uterina: estudo morfo-funcional do remodelamento celular do endométrio e expressão de fatores envolvidos na preparação para implantação embrionária." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-05112013-155805/.

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Evidências epidemiológicas associam diferentes fatores ambientais, tais como poluição e ingestão de alimentos contaminados, com desfechos gestacionais negativos e fertilidade diminuída em humanos. Não há duvidas de que a poluição do ar nos grandes centros urbanos é capaz de provocar desfechos negativos sobre a gestação: baixo peso ao nascer, prematuridade, perda gestacional, entre outros. Entretanto, poucos estudos foram conduzidos para avaliar um possível efeito da exposição à poluição ambiental particulada do ar sobre a saúde reprodutiva feminina. O objetivo deste trabalho foi avaliar se a e

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23

Sun, Congshan. "Effect of pre-implantation maternal low protein diet on embryos and embryoid bodies." Thesis, University of Southampton, 2014. https://eprints.soton.ac.uk/363661/.

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Previous studies have shown that poor maternal nutrition during pregnancy may induce metabolic syndrome in adults. In this study, we explored the mechanisms of how maternal low protein diet during the first 3.5 days of pregnancy, programs embryo development and embryonic stem cell function. Our results showed that mouse maternal low protein diet (9% casein; Emb-LPD) enhanced both Clathrin dependent and independent endocytosis in both in vivo blastocysts and in vitro differentiated embryoid bodies (EB day 5) compared with maternal normal protein diet (18% casein; NPD) controls. This increase in

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24

Lindgren, Karin E. "The Histidine-rich Glycoprotein in Reproduction." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300769.

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Infertility affects 15% of reproductive-aged couples. The milieu surrounding the growing embryo is of outmost importance, and should be optimised during in vitro fertilisation (IVF). Many biological processes, such as angiogenesis, coagulation, and immune processes need to be well regulated for a pregnancy to occur and progress normally. Histidine-rich glycoprotein (HRG) is a plasma protein that regulates components of these systems by building complexes with various ligands. A single nucleotide polymorphism (SNP) in HRG, denoted HRG C633T, seem to be of importance for IVF treatment outcomes.

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25

Piger, Veronika. "Einfluss immunologischer Mechanismen bei der Implantation von Embryonen und deren therapeutischer Nutzen im Rahmen des IVF-Programms." Doctoral thesis, [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963988859.

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26

Boudjenah, Radia. "Impact des polymorphismes génétiques sur les chances individuelles des patientes prises en charge en AMP." Versailles-St Quentin en Yvelines, 2012. http://www.theses.fr/2012VERS0037.

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L’aide médicale à la procréation constitue aujourd’hui le premier traitement pour les infertilités, mais malgré de nombreux progrès enregistrés, les taux de succès restent autour de 30% par cycle. La réponse ovarienne aux gonadotrophines et l’implantation embryonnaire demeurent très variables entre les patientes et très difficile à prévoir. Notre travail a porté sur l’étude de l’impact des polymorphismes génétiques sur la réponse ovarienne et sur l’implantation embryonnaire. Sur les 13 polymorphismes génétiques analysés, le résultat de la stimulation ovarienne, objectivés par le nombre d’ovocy

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27

Gurchenkov, Vasily. "The functional study of the asymmetric specific element of the Nodal gene during the early mouse development." Paris 6, 2009. http://www.theses.fr/2009PA066056.

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Le travail décrit dans ce manuscrit est une étude du fonctionnement de la voie de signalisation du facteur de type TGF-beta Nodal pendant l’embryogenèse précoce de la souris. Ce travail est centré sur l’analyse de l’activité de l’ASE, une séquence régulatrice du gène Nodal. Cette séquence est une cible de la voie de signalisation Smad2,3, qui transduit le signal Nodal, et permet donc au gène Nodal d’amplifier sa propre expression. Des lignées transgéniques où l’expression de protéines fluorescentes est placée sous le contrôle de l’ASE avaient été générées au laboratoire. La caractérisation de

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28

Déchaud, Hervé. "Développement et évaluation de la falloposcopie : application à la compréhension des stérilités tubaires et de leurs conséquences." Montpellier 1, 1998. http://www.theses.fr/1998MON1T023.

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29

Vitorino, Carvalho Anaïs. "Contribution à la caractérisation de l’expression, de la régulation et des rôles biologiques de STAT1 dans l’endomètre bovin au cours de la gestation précoce." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA11T067.

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Au cours de la gestation précoce, la régulation de la physiologie endométriale est cruciale au bon déroulement de l’implantation. Chez les mammifères, une famille de facteurs de transcription est fortement impliquée dans la régulation de la physiologie endométriale, les facteurs STAT. Chez la vache, des analyses haut-débit ont révélé que l’expression endométriale de STAT1 est régulée au cours de la période préimplantatoire. Le but de cette thèse est donc d’apporter de nouvelles données sur l’expression et la régulation endométriales de STAT1 mais également sur ses fonctions biologiques au cour

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30

Duval, Fabien. "Rôles de l'adiponectine à l'interface foeto-maternelle humaine au cours du premier trimestre de grossesse." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLV070/document.

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L’implantation embryonnaire repose sur une synchronisation spatio-temporelle entre un placenta fonctionnel et un endomètre réceptif. La réceptivité endométriale requiert la différenciation des cellules stromales en cellules déciduales sous l’effet des hormones ovariennes (œstrogènes et progestérone). Le placenta est un organe transitoire constitué de deux types cellulaires. Le cytotrophoblaste villeux est responsable des échanges fœtaux maternels et de la fonction endocrine du placenta. Le cytotrophoblaste extravilleux présente des propriétés invasives et assure ainsi l’ancrage du placenta dan

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31

Rahmati, Mona. "Granulocyte-Colony Stimulating Factor and Embryo Implantation Process : Effects on Human Endometrium and on Murine Abortion Prone Model CBA/J x DBA/2." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T048/document.

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L’immunologie de la reproduction englobe les principes de l’immunologie générale et les aspects spécifiques de la reproduction et du développement. Les Colony Stimulating Factors (CSFs) sont une illustration de l'application médicale de ce domaine. Dans la famille des CSFs, le Granulocyte-Colony Stimulating Factor (G-CSF) apparaît aujourd'hui comme une thérapie innovante dans divers cas d'échec de la reproduction, bien que ses cibles et ses effets ne soient pas encore clairement établis. Dans ce travail, à travers une revue sur les CSFs dans la reproduction, une étude consacrée aux gènes cible

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32

Hsu, Wen-Ling, and 徐玟鈴. "Physiological role of the embryonic progesterone receptor in the implantation and post-implantation development." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/b3aw3j.

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碩士<br>國立屏東科技大學<br>生物科技系所<br>105<br>Progesterone, a steroid hormone plays an important role in gestation, female menstrual cycle and implantation. Must be P4 and progesterone receptor combination can trigger action. If P4 and PR antagonist-RU486 binding will cause P4 can not its function. Previous studies have focused more on the effect of progesterone on the endometrium of uterus rather than on embryo development. In this study, we investigated the roles of progesterone in mouse embryo development and implantation. We examined the effects of RU486 (2x10-9 to 2x10-5M) on mouse embryonic cell gr

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33

Landrock, Danilo. "Acyl CoA Binding Protein (ACBP) Gene Ablation Induces Pre-Implantation Embryonic Lethality in Mice." Thesis, 2010. http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-9003.

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Unique among the intracellular lipid binding proteins, acyl CoA binding protein (ACBP) exclusively binds long chain fatty acyl CoAs (LCFA-CoAs). To test if ACBP is an essential protein in mammals, the ACBP gene was ablated by homologous recombination in mice. While ACBP heterozygotes appeared phenotypically normal, intercrossing of the heterozygotes did not result in any live homozygous deficient (null) ACBP^(-/-) pups. Heterozygous and wild type embryos were detected at all postimplantation stages, but no homozygous ACBP null embryos were obtained– suggesting that an embryonic lethality occur

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34

Llerena, Evelyn M. "Embryonic and Uterine Characteristics of Diapause." Thèse, 2011. http://hdl.handle.net/1866/6952.

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L’implantation retardée ou diapause embryonnaire décrit l'arrêt ou le retardement pendant l'embryogenèse. Chez le vison, la diapause est corrélée avec une sécrétion pituitaire insuffisante de la prolactine, ayant pour résultat la différentiation incomplète du corpus luteum et réduction de la progestérone. Des études antérieures suggèrent que le blastocyste de vison en diapause demeure dans un état de quiescence ou se développe lentement. Pour élucider ceci, la réplication de l'ADN a été étudiée. Les résultats démontrent synthèse de l’ADN et prolifération cellulaire dans les embryons au stade d

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35

Huang, Tzu-Wei, and 黃子瑋. "Effects and regulatory mechanisms of berberine on mouse embryonic development in both pre- and post-implantation stages." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/zdwk86.

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碩士<br>中原大學<br>生物科技研究所<br>99<br>Berberine is an alkaloid isolated from Coptis Chinensis, Phellodendron and other plant extracts. Berberine is a traditional Chinese medicine in China which has been applied for a long time. Berberine has been evaluated as anti-diarrhea, anti-bacterial, anti-arrhythmic, anti-vascular smooth muscle proliferation and cholesterol-lowering. Berberine also performs a wide range of applications in the cardiovascular system and nervous system diseases. Several studies have demonstrated that berberine is able to induce apoptosis process in cancer cells. However, a study r

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36

Liao, Chen-Yi, and 廖珍頤. "The role of ECM in the migration of embryonic stem cells and trophoblast cells: implication in early embryo development and embryo implantation." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/30430593392166353822.

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碩士<br>國立陽明大學<br>解剖暨細胞生物學研究所<br>96<br>Extracellular matrix (ECM) plays an important role in embryo implantation and embryogenesis, since previous studies have shown that functional blockade of ECM receptors results in implantation failure and deficiency in ECM proteins causes embryonic lethality. Interaction between ECM proteins and their receptors, integrins, promotes cellular migration, which is critical for embryo implantation and development. In this study, we compared the effects of various ECM proteins on the migration of embryonic stem (ES) cells and trophoblast cells of the blastocyst

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37

Shen, Jin-Te, and 沈金德. "The Roles of Intracellular Calcium Fluxes and Signaling in the Spreading of Trophoblast Cells on Endometrial Epithelium during Embryonic Implantation – an In Vitro Model System." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/68241036816432251550.

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碩士<br>國立陽明大學<br>解剖暨細胞生物學研究所<br>92<br>The Ca2+ ion as a secondary messenger, mediated many signaling pathway, including cytochrome c release, tight junction formation and cell migration ability. During implantation, complex embryo-endometrium interaction result in blastocyst adhesion. At the implantation site, the Ca2+ ion play an important role to mediate the interaction between trophoblast and endometrial epithelial cells, the function is still unclear. To role out the function of Ca2+ mediated the trophoblast and endometrial epithelial cells at the implantation stage. RL95-2 cells grow to co

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38

Pribadi, Tyas Agung. "Hormonal induction of ovulation in banded morwong, Cheilodactylus spectabilis, and greenback flounder, Rhombosolea tapirina, using LHRHa implantation and the embryonic and larval development of greenback flounder incubated under various temperature regimes." Thesis, 1996. https://eprints.utas.edu.au/21272/1/whole_PribadiTyasAgung1996_thesis.pdf.

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39

Piger, Veronika [Verfasser]. "Einfluß immunologischer Mechanismen bei der Implantation von Embryonen und deren therapeutischer Nutzen im Rahmen des IVF-Programms / vorgelegt von Veronika Piger." 2001. http://d-nb.info/963988859/34.

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40

Desmarais, Joëlle. "Les interactions foeto-maternelles et l'implantation embryonnaire chez le vison." Thèse, 2007. http://hdl.handle.net/1866/18029.

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41

Yang, Chun-Ru, and 楊淳茹. "The embryoid body as a model system to study the effect of heat stress on post-implantation development of mammalian embryos." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/2d654s.

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碩士<br>國立中興大學<br>動物科學系所<br>101<br>The odjectives of this study were to establish an in vitro system to determine the effect of heat shock on germ layer differentiation, heat shock protein (hsp70) expression and apoptosis markers of mouse and rabbit embryoid bodies (EB). In Exp. 1, 5.5-8.5 day-old mouse fetuses and 1-7 day-old mouse EBs were collected to examine their gene expressions of the three germ layers. Results showed that Days 3 and 6 EBs are retrospectively associated with the Days 6.5 and 7.5 fetuses, respectively, in terms of the germ layer gene expressions. In Exp. 2.1, mouse EBs wer

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