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1

Pakrasi, Pranab Lal, and Anjana Tiwari. "Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx." Animal Reproduction Science 101, no. 1-2 (2007): 179–85. https://doi.org/10.5281/zenodo.13423762.

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(Uploaded by Plazi for the Bat Literature Project) Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to
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2

Pakrasi, Pranab Lal, and Anjana Tiwari. "Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx." Animal Reproduction Science 101, no. 1-2 (2007): 179–85. https://doi.org/10.5281/zenodo.13423762.

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(Uploaded by Plazi for the Bat Literature Project) Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to
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3

Pakrasi, Pranab Lal, and Anjana Tiwari. "Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx." Animal Reproduction Science 101, no. 1-2 (2007): 179–85. https://doi.org/10.5281/zenodo.13423762.

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(Uploaded by Plazi for the Bat Literature Project) Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to
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4

Pakrasi, Pranab Lal, and Anjana Tiwari. "Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx." Animal Reproduction Science 101, no. 1-2 (2007): 179–85. https://doi.org/10.5281/zenodo.13423762.

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(Uploaded by Plazi for the Bat Literature Project) Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to
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5

Pakrasi, Pranab Lal, and Anjana Tiwari. "Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx." Animal Reproduction Science 101, no. 1-2 (2007): 179–85. https://doi.org/10.5281/zenodo.13423762.

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(Uploaded by Plazi for the Bat Literature Project) Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to
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6

Pakrasi, Pranab Lal, and Anjana Tiwari. "Evidence of increased endometrial vascular permeability at the time of implantation in the short-nosed fruit bat, Cyanopterus sphinx." Animal Reproduction Science 101, no. 1-2 (2007): 179–85. https://doi.org/10.5281/zenodo.13423762.

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(Uploaded by Plazi for the Bat Literature Project) Early embryonic development and implantation were studied in tropical short-nosed fruit bat Cyanopterus sphinx. We report preimplantation development and embryo implantation. Different stages of cleavage were observed in embryo by direct microscopic examination of fresh embryos after retrieving them either from the oviduct or the uterus at different days, up to the day of implantation. Generally, the embryos enter the uterus at the 8-cell stage. Embryonic development continued without any delay and blastocyst were formed showing attachment to
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7

Simón, Carlos, Julio Martín, Arancha Galan, Diana Valbuena, and Antonio Pellicer. "Embryonic Regulation in Implantation." Seminars in Reproductive Medicine 17, no. 03 (1999): 267–74. http://dx.doi.org/10.1055/s-2007-1016234.

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8

Krüssel, Jan-S., Peter Bielfeld, Mary Lake Polan, and Carlos Simón. "Regulation of embryonic implantation." European Journal of Obstetrics & Gynecology and Reproductive Biology 110 (September 2003): S2—S9. http://dx.doi.org/10.1016/s0301-2115(03)00167-2.

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9

Barkai, Uriel, and Perry F. Kraicer. "Intrauterine Signaling and Embryonic Implantation." Neurosignals 5, no. 2 (1996): 111–21. http://dx.doi.org/10.1159/000109180.

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10

Artus, Jérôme, Isabelle Hue, and Hervé Acloque. "Preimplantation development in ungulates: a ‘ménage à quatre’ scenario." Reproduction 159, no. 3 (2020): R151—R172. http://dx.doi.org/10.1530/rep-19-0348.

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In ungulates, early embryonic development differs dramatically from that of mice and humans and is characterized by an extended period of pre- and peri-implantation development in utero. After hatching from the zona pellucida, the ungulate blastocyst will stay free in the uterus for many days before implanting within the uterine wall. During this protracted peri-implantation period, an intimate dialog between the embryo and the uterus is established through a complex series of paracrine signals. The blastocyst elongates, leading to extreme growth of extra-embryonic tissues, and at the same tim
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11

Szekeres-Bartho, Julia. "Successful Implantation from the Embryonic Aspect." American Journal of Reproductive Immunology 75, no. 3 (2015): 382–87. http://dx.doi.org/10.1111/aji.12448.

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12

Osório, Joana. "A microRNA prevents cervical embryonic implantation." Nature Reviews Endocrinology 10, no. 8 (2014): 445. http://dx.doi.org/10.1038/nrendo.2014.93.

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13

Poirier, F., C. T. Chan, P. M. Timmons, E. J. Robertson, M. J. Evans, and P. W. Rigby. "The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo." Development 113, no. 4 (1991): 1105–14. http://dx.doi.org/10.1242/dev.113.4.1105.

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The differentiation in vitro of murine embryonic stem cells to embryoid bodies mimics events that occur in vivo shortly before and after embryonic implantation. We have used this system, together with differential cDNA cloning, to identify genes the expression of which is regulated during early embryogenesis. Here we describe the isolation of several such cDNA clones, one of which corresponds to the gene H19. This gene is activated in extraembryonic cell types at the time of implantation, suggesting that it may play a role at this stage of development, and is subsequently expressed in all of t
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14

Novaro, V., E. González, A. Jawerbaum, V. Rettori, G. Canteros, and M. F. Gimeno. "Nitric oxide synthase regulation during embryonic implantation." Reproduction, Fertility and Development 9, no. 5 (1997): 557. http://dx.doi.org/10.1071/r97005.

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It has previously been demonstrated that uterine nitric oxide synthase (NOS) activity increases before embryonic implantation in rats. The aim of the present work was to investigate the regulation and the physiological relevance of the nitric oxide (NO) system in ovoimplantation. The increase in NOS activity in early pregnancy was found to be independent of the presence of embryos in the uterus. Whereas the Ca2+-dependent isoform of NOS increased gradually in the preimplantation days, the Ca2+-independent isoform increased just at the beginning of implantation (Day 5, 1800 hours); then the act
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15

Fujiwara, Hiroshi, Masanori Ono, Yukiyasu Sato, et al. "Promoting Roles of Embryonic Signals in Embryo Implantation and Placentation in Cooperation with Endocrine and Immune Systems." International Journal of Molecular Sciences 21, no. 5 (2020): 1885. http://dx.doi.org/10.3390/ijms21051885.

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Embryo implantation in the uterus is an essential process for successful pregnancy in mammals. In general, the endocrine system induces sufficient embryo receptivity in the endometrium, where adhesion-promoting molecules increase and adhesion-inhibitory molecules decrease. Although the precise mechanisms remain unknown, it is widely accepted that maternal–embryo communications, including embryonic signals, improve the receptive ability of the sex steroid hormone-primed endometrium. The embryo may utilize repulsive forces produced by an Eph–ephrin system for its timely attachment to and subsequ
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16

Bazer, Fuller W., and Gregory A. Johnson. "Early Embryonic Development in Agriculturally Important Species." Animals 14, no. 13 (2024): 1882. http://dx.doi.org/10.3390/ani14131882.

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The fertilization of oocytes ovulated by pigs, sheep, cows, and horses is not considered a limiting factor in successful establishment of pregnancy. Pig, sheep, and cow embryos undergo cleavage to the blastocyst stage, hatch from the zona pellucida, and undergo central-type implantation. Hatched blastocysts of pigs, sheep, and cows transition from tubular to long filamentous forms to establish surface area for exchange of nutrients and gases with the uterus. The equine blastocyst, surrounded by external membranes, does not elongate but migrates throughout the uterine lumen before attaching to
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17

Navarro, M., C. Bluguermann, M. Von Meyeren, V. Bariani, C. Osycka, and A. Mutto. "2 Role of histone H3 lysine 9 trimethylation during bovine pre-implantation embryonic development." Reproduction, Fertility and Development 31, no. 1 (2019): 126. http://dx.doi.org/10.1071/rdv31n1ab2.

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Histones play an important role in DNA’s compaction and organisation into the cellular nucleus. Depending on which histone modification occurs, chromatin can take a conformation of heterochromatin or euchromatin, which are associated with gene repression or expression, respectively. Histone H3 lysine 9 (H3K9) trimethylation (H3K9me3) is associated with gene silencing. At least 3 methyltransferases are able to change the methylation status of H3K9: SUV39H1, SUV39H2, and SETDB1. In several mammalian species, modulation of H3K9 methylation status has been demonstrated to be necessary to achieve a
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18

Minder, Jessica L., Sarah B. Winokur, Janaye Stephens, et al. "Oxytocin Induces Embryonic Diapause." Obstetrical & Gynecological Survey 80, no. 7 (2025): 423–24. https://doi.org/10.1097/ogx.0000000000001424.

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(Abstracted from Sci Adv 2025;11(10):eadt1763, doi:10.1126/sciadv.adt1763 Embryonic diapause is defined as a paused state in embryonic development before implantation that is reversible. In mice, this has been shown to occur in pregnancies triggered by maternal duress or nursing a previous litter.
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19

Riveiro, Alba Redó, and Joshua Mark Brickman. "From pluripotency to totipotency: an experimentalist's guide to cellular potency." Development 147, no. 16 (2020): dev189845. http://dx.doi.org/10.1242/dev.189845.

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ABSTRACTEmbryonic stem cells (ESCs) are derived from the pre-implantation mammalian blastocyst. At this point in time, the newly formed embryo is concerned with the generation and expansion of both the embryonic lineages required to build the embryo and the extra-embryonic lineages that support development. When used in grafting experiments, embryonic cells from early developmental stages can contribute to both embryonic and extra-embryonic lineages, but it is generally accepted that ESCs can give rise to only embryonic lineages. As a result, they are referred to as pluripotent, rather than to
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20

Polan, M. L., C. Simon, A. Frances, B. Y. Lee, and L. E. Prichard. "Role of embryonic factors in human implantation." Human Reproduction 10, suppl 2 (1995): 22–29. http://dx.doi.org/10.1093/humrep/10.suppl_2.22.

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21

Edwards, R. G. "New concepts in embryonic growth and implantation." Human Reproduction 13, suppl 3 (1998): 271–82. http://dx.doi.org/10.1093/humrep/13.suppl_3.271.

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22

Gómez, Eva, Maria Ruíz-Alonso, Jose Miravet, and Carlos Simón. "Human Endometrial Transcriptomics: Implications for Embryonic Implantation." Cold Spring Harbor Perspectives in Medicine 5, no. 7 (2015): a022996. http://dx.doi.org/10.1101/cshperspect.a022996.

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23

Cioffi, Alfred. "Early Human Embryonic Development: Individuation before Implantation." Linacre Quarterly 62, no. 1 (1995): 70–73. http://dx.doi.org/10.1080/20508549.1995.11878294.

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24

Lee, Jong-Eun, Hyun-Ah Oh, Haengseok Song, et al. "Autophagy Regulates Embryonic Survival During Delayed Implantation." Endocrinology 152, no. 5 (2011): 2067–75. http://dx.doi.org/10.1210/en.2010-1456.

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25

Cooke, I. D. "Session 18. Implantation stage of embryonic development." Human Reproduction 5, Supplement (1990): 33. http://dx.doi.org/10.1093/humrep/5.supplement.33.

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26

Gunnala, V., I. Matei, M. Toschi, et al. "Characterization of human pre-implantation embryonic exosomes." Fertility and Sterility 110, no. 4 (2018): e81. http://dx.doi.org/10.1016/j.fertnstert.2018.07.244.

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27

Jaiswal, Yogesh Kumar, Madan Mohan Chaturvedi, and Kaushik Deb. "Effect of Bacterial Endotoxins on Superovulated Mouse Embryos In Vivo: Is CSF-1 Involved in Endotoxin-Induced Pregnancy Loss?" Infectious Diseases in Obstetrics and Gynecology 2006 (2006): 1–9. http://dx.doi.org/10.1155/idog/2006/32050.

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Mammalian embryonic development is regulated by several cytokines and growth factors from embryonic or maternal origins. Since CSF-1 plays important role in embryonic development and implantation, we investigated its role in gram-negative bacterial LPS-induced implantation failure. The effect of LPS on normal (nonsuperovulated) and superovulated in vivo-produced embryos was assessed by signs of morphological degeneration. A significantly similar number of morphologically degenerated embryos recovered from both nonsuperovulated and superovulated LPS treated animals on day 2.5 of pregnancy onwar
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28

Hearn, John P. "Embryo implantation and embryonic stem cell development in primates." Reproduction, Fertility and Development 13, no. 8 (2001): 517. http://dx.doi.org/10.1071/rd01068.

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The endocrine dialogue that results in implantation and the successful establishment of pregnancy in primates relies on embryonic secretion of chorionic gonadotrophin (CG). This hormone is a signal of embryo viability and capacity to support the corpus luteum. The expression of CG is apparently restricted to primates. Active or passive immunization of marmoset monkeys against the beta subunit of CG prevented implantation and early pregnancy, without disrupting the ovarian cycle. Studies of individual embryos cultured in vitro showed that CG is secreted at low levels by the blastocyst from befo
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29

Suemori, H., S. Hashimoto, and N. Nakatsuji. "Presence of the adenovirus E1A-like activity in preimplantation stage mouse embryos." Molecular and Cellular Biology 8, no. 8 (1988): 3553–55. http://dx.doi.org/10.1128/mcb.8.8.3553-3555.1988.

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The presence of the adenovirus E1A-like activity in embryonal carcinoma stem cells has been reported. We now show that preimplantation stage mouse embryonic cells allow transcription of the E1A-dependent E2A gene when infected with E1A-deleted mutant dl312, indicating the presence of the E1A-like activity in morulae and blastocysts. Moreover, such activity seems to decrease or disappear at about the time of implantation.
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30

Suemori, H., S. Hashimoto, and N. Nakatsuji. "Presence of the adenovirus E1A-like activity in preimplantation stage mouse embryos." Molecular and Cellular Biology 8, no. 8 (1988): 3553–55. http://dx.doi.org/10.1128/mcb.8.8.3553.

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The presence of the adenovirus E1A-like activity in embryonal carcinoma stem cells has been reported. We now show that preimplantation stage mouse embryonic cells allow transcription of the E1A-dependent E2A gene when infected with E1A-deleted mutant dl312, indicating the presence of the E1A-like activity in morulae and blastocysts. Moreover, such activity seems to decrease or disappear at about the time of implantation.
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31

Shufaro, Yoel, and Joseph G. Schenker. "Implantation Failure, Etiology, Diagnosis and Treatment." International Journal of Infertility & Fetal Medicine 2, no. 1 (2011): 1–7. http://dx.doi.org/10.5005/jp-journals-10016-1009.

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ABSTRACT Embryonic implantation is a complex interaction between the embryo and the endometrium. Despite great investigative effort this process is still obscure. Contrary to the great advancement in patient care, follicular recruitment, oocyte quality and aspiration, embryo quality, culture and cryopreservation, our understanding of the implantation process did not enhance as much, and the tools to intervene within this process are limited. The implantation of the transferred embryos still remains the major limiting factor in IVF. Here we will review the current literature on the maternal (ut
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32

Calle, Alexandra, Víctor Toribio, María Yáñez-Mó, and Miguel Ángel Ramírez. "Embryonic Trophectoderm Secretomics Reveals Chemotactic Migration and Intercellular Communication of Endometrial and Circulating MSCs in Embryonic Implantation." International Journal of Molecular Sciences 22, no. 11 (2021): 5638. http://dx.doi.org/10.3390/ijms22115638.

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Embryonic implantation is a key step in the establishment of pregnancy. In the present work, we have carried out an in-depth proteomic analysis of the secretome (extracellular vesicles and soluble proteins) of two bovine blastocysts embryonic trophectoderm primary cultures (BBT), confirming different epithelial–mesenchymal transition stages in these cells. BBT-secretomes contain early pregnancy-related proteins and angiogenic proteins both as cargo in EVs and the soluble fraction. We have demonstrated the functional transfer of protein-containing secretome between embryonic trophectoderm and m
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33

Oh, Seung Yeon, Seung Bin Na, Yoo Kyung Kang, and Jeong Tae Do. "In Vitro Embryogenesis and Gastrulation Using Stem Cells in Mice and Humans." International Journal of Molecular Sciences 24, no. 17 (2023): 13655. http://dx.doi.org/10.3390/ijms241713655.

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During early mammalian embryonic development, fertilized one-cell embryos develop into pre-implantation blastocysts and subsequently establish three germ layers through gastrulation during post-implantation development. In recent years, stem cells have emerged as a powerful tool to study embryogenesis and gastrulation without the need for eggs, allowing for the generation of embryo-like structures known as synthetic embryos or embryoids. These in vitro models closely resemble early embryos in terms of morphology and gene expression and provide a faithful recapitulation of early pre- and post-i
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34

Kamemizu, Chizuru, and Toshihiko Fujimori. "Distinct dormancy progression depending on embryonic regions during mouse embryonic diapause†." Biology of Reproduction 100, no. 5 (2019): 1204–14. http://dx.doi.org/10.1093/biolre/ioz017.

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Abstract Many mammalian species undergo embryonic diapause and suspend development at the blastocyst stage before implantation, which is also known as delayed implantation. We studied the process of how mouse embryos enter a dormancy status at a cellular level. Immunofluorescent analysis of differentiation markers for epiblast, primitive endoderm, and trophectoderm suggested that cell differentiation status was maintained during 7 days in diapause. To understand the progression of cellular dormancy during diapause, we examined the expression of a transgenic cell cycle marker Fucci2 and Ki67 by
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35

Boroviak, Thorsten, and Jennifer Nichols. "The birth of embryonic pluripotency." Philosophical Transactions of the Royal Society B: Biological Sciences 369, no. 1657 (2014): 20130541. http://dx.doi.org/10.1098/rstb.2013.0541.

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Formation of a eutherian mammal requires concurrent establishment of embryonic and extraembryonic lineages. The functions of the trophectoderm and primitive endoderm are to enable implantation in the maternal uterus, axis specification and delivery of nutrients. The pluripotent epiblast represents the founding cell population of the embryo proper, which is protected from ectopic and premature differentiation until it is required to respond to inductive cues to form the fetus. While positional information plays a major role in specifying the trophoblast lineage, segregation of primitive endoder
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36

Yonaha, Hitoshi, Hiroyuki Minoura, Toshimichi Yoshida, et al. "Expression of neuropeptide Y is increased in murine endometrial epithelium during the peri-implantation period under regulation by sex steroids." Reproduction, Fertility and Development 16, no. 3 (2004): 355. http://dx.doi.org/10.1071/rd02088.

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Oligopeptide hormones are involved in cell–cell interaction during embryonal implantation and neuropeptide Y (NPY) is expressed in the human placenta and decidual cells in the third trimester of pregnancy. However, there is no report regarding the intrauterine localisation and the functions of NPY during the peri-implantation period. In the present study, the spatiotemporal changes in NPY expression in the murine uterus during the peri-implantation period were investigated using reverse transcription–polymerase chain reaction (RT-PCR), quantitative RT-PCR and immunohistochemical techniques, as
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37

He, Bo, Hangxiao Zhang, Jianqi Wang, et al. "Blastocyst activation engenders transcriptome reprogram affecting X-chromosome reactivation and inflammatory trigger of implantation." Proceedings of the National Academy of Sciences 116, no. 33 (2019): 16621–30. http://dx.doi.org/10.1073/pnas.1900401116.

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Implantation of the blastocyst into the uterus is the gateway for further embryonic development in mammals. Programming of blastocyst to an implantation-competent state known as blastocyst activation is the determining factor for implantation into the receptive uterus. However, it remains largely unclear how the blastocyst is globally programmed for implantation. Employing a delayed implantation mouse model, we show here that the blastocyst undergoes extensive programming essential for implantation. By analyzing the transcriptional profile of blastocysts with different implantation competency,
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38

Golos, Thaddeus G., M. Giakoumopoulos, and M. A. Garthwaite. "Embryonic stem cells as models of trophoblast differentiation: progress, opportunities, and limitations." REPRODUCTION 140, no. 1 (2010): 3–9. http://dx.doi.org/10.1530/rep-09-0544.

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While the determination of the trophoblast lineage and the facilitation of placental morphogenesis by trophoblast interactions with other cells of the placenta are crucial components for the establishment of pregnancy, these processes are not tractable at the time of human implantation. Embryonic stem cells (ESCs) provide an embryonic surrogate to derive insights into these processes. In this review, we will summarize current paradigms which promote trophoblast differentiation from ESCs, and potential opportunities for their use to further define signals directing morphogenesis of the placenta
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39

Shen, Ying, and Aiping Qin. "Regulation of Embryonic Signal on Talin1 in Mouse Endometrium." Reproductive Sciences 26, no. 9 (2018): 1277–86. http://dx.doi.org/10.1177/1933719118815584.

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Embryonic signals can affect the spatiotemporal-specific expression of the uterus to establish a successful pregnancy. Our previous study has found that talin1 underwent dynamic changes in the mouse endometrium during peri-implantation period. However, whether talin1 is affected by the embryo signals is not clear. In order to investigate the effect of embryonic signals, especially human chorionic gonadotropin (HCG) on talin1, we have designed mouse models of pseudopregnancy, delayed implantation and activation, and HCG treatment. Using these models, the expression of talin1 in the mouse endome
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40

Murray, P., and D. Edgar. "Regulation of the differentiation and behaviour of extra-embryonic endodermal cells by basement membranes." Journal of Cell Science 114, no. 5 (2001): 931–39. http://dx.doi.org/10.1242/jcs.114.5.931.

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Both the extracellular matrix and parathyroid hormone-related peptide (PTHrP) have been implicated in the differentiation and migration of extra-embryonic endodermal cells in the pre-implantation mammalian blastocyst. In order to define the individual roles and interactions between these factors in endodermal differentiation, we have used embryoid bodies derived from Lamc1(-/-) embryonic stem cells that lack basement membranes. The results show that in the absence of basement membranes, increased numbers of both visceral and parietal endodermal cells differentiate, but they fail to form organi
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41

Bedzhov, Ivan, Sarah J. L. Graham, Chuen Yan Leung, and Magdalena Zernicka-Goetz. "Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo." Philosophical Transactions of the Royal Society B: Biological Sciences 369, no. 1657 (2014): 20130538. http://dx.doi.org/10.1098/rstb.2013.0538.

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A critical point in mammalian development is when the early embryo implants into its mother's uterus. This event has historically been difficult to study due to the fact that it occurs within the maternal tissue and therefore is hidden from view. In this review, we discuss how the mouse embryo is prepared for implantation and the molecular mechanisms involved in directing and coordinating this crucial event. Prior to implantation, the cells of the embryo are specified as precursors of future embryonic and extra-embryonic lineages. These preimplantation cell fate decisions rely on a combination
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42

Moreno-Moya, J. M., N. A. Franchi, S. Martínez-Escribano, et al. "Transcriptome of early embryonic invasion at implantation sites in a murine model." Reproduction, Fertility and Development 28, no. 10 (2016): 1487. http://dx.doi.org/10.1071/rd14166.

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Successful implantation relies on the interaction between a competent embryo and a receptive endometrium. The aim of the present study was to investigate genes differentially expressed in early invasive embryonic tissue versus decidual tissue in mice. Samples were obtained from the ectoplacental cone, the immediately surrounding deciduas and from deciduas from interimplantation sites. Microarray analysis showed that 817 genes were differentially expressed between extra-embryonic tissue and the surrounding decidua and that 360 genes were differentially expressed between the different deciduas,
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43

Nie, Li, You-bo Zhao, Dan Zhao, et al. "Progesterone-induced miR-152 interferes with embryonic implantation by downregulating GLUT3 in endometrial epithelium." American Journal of Physiology-Endocrinology and Metabolism 316, no. 4 (2019): E557—E567. http://dx.doi.org/10.1152/ajpendo.00245.2018.

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To investigate the role of progesterone-induced micro-RNA (miR)-152 in early embryonic development and implantation by regulating GLUT3 in endometrial epithelium, qRT-PCR was used to detect the expression of miR-152, GLUT1, and GLUT3 in the endometrial epithelial cells of female mice. GLUT1 and GLUT3 proteins were detected by immunohistochemical staining in the mouse endometrial epithelium. Bioinformatics prediction associated with a luciferase assay was performed to determine whether GLUT1 and GLUT3 are target genes of miR-152. Specific miR-152 mimics or inhibitors were transfected into the e
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44

Vitiello, Danielle, and Pasquale Patrizio. "Implantation and Early Embryonic Development: Implications for Pregnancy." Seminars in Perinatology 31, no. 4 (2007): 204–7. http://dx.doi.org/10.1053/j.semperi.2007.05.006.

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45

Soares, Michael J. "Embryo implantation - coordination of maternal and embryonic adaptations." International Journal of Developmental Biology 58, no. 2-3-4 (2014): 71–74. http://dx.doi.org/10.1387/ijdb.140086ms.

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46

Suginami, Hiroshi. "Endocrine Regulation of Early Embryonic Development and Implantation." Hormone Research 44, no. 2 (1995): 1–3. http://dx.doi.org/10.1159/000184652.

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47

Simón, Carlos. "CLINICAL IMPACT OF MATERNAL-EMBRYONIC COMMUNICATION AT IMPLANTATION." Reproductive BioMedicine Online 39 (August 2019): e6-e7. http://dx.doi.org/10.1016/j.rbmo.2019.04.024.

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48

BULLETTI, C., V. POLLI, F. LICASTRO, and R. PARMEGGIANI. "Endometrial and Embryonic Factors Involved in Successful Implantation." Annals of the New York Academy of Sciences 734, no. 1 The Human End (1994): 221–31. http://dx.doi.org/10.1111/j.1749-6632.1994.tb21750.x.

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49

Gandolfi, F., T. A. L. Brevini, S. Modina, and L. Passoni. "Early embryonic signals: embryo-maternal interactions before implantation." Animal Reproduction Science 28, no. 1-4 (1992): 269–76. http://dx.doi.org/10.1016/0378-4320(92)90113-r.

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50

Irollo, Alfonso Maria, Maria Francesca Gangale, Gennaro Calabrese, et al. "H.A.R.O.T. Human assisted reproduction ozone therapy: the use of Oxygen-Ozone therapy as an adjunct in the therapy of couple sterility." Ozone Therapy 4, no. 3 (2019): 64–67. http://dx.doi.org/10.4081/ozone.2019.8700.

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The increase in couple sterility and the average increase in the age of women seeking pregnancy has placed the scientific community in front of the need to improve the quality of oocytes and the percentage of the embryonic implantation. The oxygen- ozone therapy seems to be able to help in this research thanks to its modes of action. A therapeutic protocol, identified with the acronym H.A.R.O.T (Human assisted reproduction ozone therapy) has been developed, the first results of which seem to be considerably encouraging in order to obtain a greater number and quality of oocytes and improve the
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