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Tesis sobre el tema "Functionnal responses"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 14 de febrero de 2022

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1

Shamji, Mohamed Hussein. "Grass pollen immunotherapy : Immunoreactive and functional antibody responses and their relationship to clinical response." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526400.

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2

Canaud, Matthieu. "Estimation de paramètres et planification d’expériences adaptée aux problèmes de cinétique - Application à la dépollution des fumées en sortie des moteurs." Thesis, Saint-Etienne, EMSE, 2011. http://www.theses.fr/2011EMSE0619/document.

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Les modèles physico-chimiques destinés à représenter la réalité expérimentale peuvent se révéler inadéquats. C'est le cas du piège à oxyde d'azote, utilisé comme support applicatif de notre thèse, qui est un système catalytique traitant les émissions polluantes du moteur Diesel. Les sorties sont des courbes de concentrations des polluants, qui sont des données fonctionnelles, dépendant de concentrations initiales scalaires.L'objectif initial de cette thèse est de proposer des plans d'expériences ayant un sens pour l'utilisateur. Cependant les plans d'expérience s'appuyant sur des modèles, l'es

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3

Buitrago, Murcia Claudia Lorena. "Cbl proteins in platelet functional responses." Diss., Temple University Libraries, 2012. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/198139.

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Physiology<br>Ph.D.<br>c-Cbl protein functions as an E3 ligase and scaffolding protein, where three residues, Y700, Y731, and Y774, upon phosphorylation, have been shown to initiate several signaling cascades. In this study, we investigated the role of these phospho-tyrosine residues in the platelet functional responses upon integrin engagement. We observed that c-Cbl Y700, Y731 and Y774 undergo phosphorylation upon platelet adhesion to immobilized fibrinogen, which was inhibited in the presence of PP2, a pan-src family kinase (SFK) inhibitor, suggesting that c-Cbl is phosphorylated downstream

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4

Rowe, James Benedict. "Functional imaging of response selection." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398891.

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5

Smith, Carine. "Exercise, stress and immune system functional responses." Thesis, Stellenbosch : University of Stellenbosch, 2004. http://hdl.handle.net/10019.1/16070.

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Dissertation (PhD)--University of Stellenbosch, 2004.<br>ENGLISH ABSTRACT: Stress related to chronic exercise affects both the immune and endocrine systems, but there are still many issues that are poorly understood, particularly effects of stress on the functional capacity of immune cells. This thesis probed some of these issues using physiological models of physical and psychological stress. Both exercise training stress and chronic psychological stress in human subjects were shown to result in an up-regulation of spontaneous reactivity of white blood cells in vitro, using two different

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6

Dodd, Garron. "Appetite and functional brain responses to cannabinoids." Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/appetite-and-functional-brain-responses-to-cannabinoids(b2b4f7e8-d711-421e-867e-fcf017bfccf0).html.

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The obesity epidemic is a major health threat affecting one in four people in the affluent western world, where high-energy foods are easily available and there is little need for exercise. To identify novel therapeutic targets for the treatment of obesity, one important step is to further define the complex circuitry in the brainwhich is ultimately responsible for our appetite and body weight regulation. Although complex, appetite can be thought of as having two distinct, though none mutually exclusive, aspects: the need to eat (homeostatic) and the desire to eat(hedonistic).The need to eat,

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7

Sullivan, Daniel Michael. "Molecular and Structural Characterization of Proteins Involved in Bacterial Adaptive Responses." NCSU, 2008. http://www.lib.ncsu.edu/theses/available/etd-03252008-122146/.

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Bacteria are remarkable in their ability to adapt to environmental conditions that are continually in flux between growth-promoting and growth-limiting. Responses to a host of environmental situations are equally varied, ranging from the secretion of antimicrobial compounds and polymer degrading enzymes, to the up-regulation of alternative cellular developmental pathways leading to complete physiological transformation. In endospore forming bacteria this results in a metabolically inert, yet highly resistant endospore. The first study presented here deals with the NMR structural and dynamic ch

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8

Burnham, Katie. "Functional genomics of the sepsis response." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:cb98af40-1b66-4966-a643-ae8dfec2c122.

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Sepsis is defined as a dysregulated immune response to infection causing organ dysfunction, and is a major area of unmet clinical need. Although conventionally considered a unified disease with a common pathway to organ failure and death, substantial clinical and molecular heterogeneity is seen, which has limited efforts to understand pathophysiology and improve therapeutic strategies. Sepsis is associated with global changes in gene expression, and genetic variants are known to affect the response to infection. This thesis therefore uses an integrated functional genomics approach to investiga

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9

Lapointe, Michael F. "Numerical and functional responses of British Columbia trawlers." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/27578.

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Numerical responses were examined in the movement of trawlers among seven aggregate fishing areas off the British Columbia coast. Three hypotheses for movement patterns were tested: (1) Movement follows traditional patterns, (2) Movement equalizes the gross dollar returns to effort (LPE$) in each area, and (3) Movement maintains relative LPE$ in each area. On the interannual time scale, I rejected the Equalize LPE$ hypothesis, but failed to reject either the Traditional Patterns or Maintain Relative LPE$ hypothesis. On the intra-annual time scale, I rejected both LPE$ hypotheses, but was unabl

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10

Gibson, Christine M. "Response Patterns in Functional Analyses: a Preliminary Analysis." Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc149594/.

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Functional assessment procedures have proven effective in identifying the operant contingencies that maintain problem behavior. Typically, the evaluation of responding during functional analyses is conducted at the condition level. However, some variables affecting occurrences of behavior cannot be evaluated solely through the use of a cross-session analysis. Evaluating within-session patterns of responding may provide information about variables such as extinction bursts, discriminative stimuli, and motivating operations such as deprivation and satiation. The current study was designed to ide

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11

Passador-Gurgel, Gisele Candia. "Quantitative Trait Transcript Mapping for Drug Response in Drosophila melanogaster." NCSU, 2005. http://www.lib.ncsu.edu/theses/available/etd-11132005-160424/.

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Here I used microarrays to identify genes that are activated or repressed by nicotine and caffeine in Drosophila melanogaster. I compared genotypes with differential resistance to each drug in order to select genes that may be involved in resistance to the drugs. Comparison of the genes differentially expressed by both drugs leads me to propose that there are common mechanisms of metabolic resistance to caffeine and nicotine, in particular cytochrome P-450-mediated mechanisms. Caffeine seems to have a more dramatic influence on gene expression than nicotine, in particular on expression of gene

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12

Ignace, Danielle Denise. "Functional Responses of Sonoran Desert Plant Species to Precipitation." Diss., The University of Arizona, 2006. http://hdl.handle.net/10150/196132.

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Arid and semi-arid ecosystems of the southwestern U.S. are experiencing major changes that have profound impacts for community structure and ecosystem function. First, these ecosystems are experiencing dramatic shifts in vegetation composition as a result of the invasion of non-native species. Second these ecosystems are predicted to undergo substantial shifts in climate regime, which include increases in the variability and frequency of extreme temperature and precipitation events. It is not well understood how these current and predicted changes will affect the physiological performance o

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13

Richman, Jeremy Golding 1970. "Characterization of α₂-adrenergic receptor localization and functional responses". Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/282583.

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The three α₂-adrenergic receptors (α₂-ARs) were studied in both recombinant and endogenous systems. It was my general hypothesis that the three α₂-adrenergic receptor (AR) subtypes exhibit differential tissue and subcellular localization and couple to physiological pathways to directly elicit functional responses. It was our hope, that in identifying differences between the α₂-ARs we may elucidate their physiological roles and provide a potential means for the rational development of therapeutic drugs or models of such pathologies as atherosclerosis, hypertension and glaucoma. Subtype selectiv

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14

Daikou, Sophia. "Vitamin A-induced chondrocyte responses : functional and molecular studies." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619854.

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15

Kannan, Yashaswini. "Functional Characterization Of Human IkappaBzeta In Modulating Inflammatory Responses." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1314564642.

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16

Gor, Bhoomi K. "Defining functional specificity of stress responses in Drosophila melanogaster." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7129/.

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Survival of an organism depends on its perception and response to external stressors such as infection, osmotic stress (ionic or desiccation) or xenobiotic stress. At the cellular level, stress is perceived and relayed via signal transduction pathways that alter transcription or establish new transcriptional programmes that modulate physiology at the whole-organism level to regain homeostasis and promote survival. The vital function of epithelial tissues (e.g., kidneys in vertebrates and Malpighian tubules in insects) is systemic balance of nutrient, solute and water levels. Additionally, epit

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17

Covernton, Patrick John O'Neill. "Functional aspects of neuronal nicotinic receptor diversity." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321967.

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18

Chen, Jian. "Bifurcations, Normal Forms and their Applications." Diss., Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7121.

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The first part is a study of an ecological model with one herbivore and $N$ plants. The system has a new type of functional response due to the speculation that the plants compete with each other and have different levels of toxin which inhibit the herbivore's ability to eat up to a certain amount. We first derive the model mathematically and then investigate, both analytically and numerically, the possible dynamics for this model, including the bifurcation and chaos. We also discuss the conditions under which all the species can coexist. The second part is a study in the normal form the

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19

Rhodes, Rachelle Renee. "Investigating the Functional Response of a Subsurface Biofilm Community to Xenobiotic Stress." Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/33412.

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Biologically-mediated subsurface remediation by biofilm communities is a poorly understood process that is spatially and temporally dynamic. Two microbial responses, catabolism and the stress response glutathione-gated potassium efflux (GGKE), to benzene, pentachlorophenol (PCP), or Cd exposure were studied in up-flow sand columns to examine the contribution of each response to the overall functional response of a subsurface biofilm. Benzene was catabolized in the aerobic zone, and did not activate the GGKE response, and exhibited the highest biomass concentrations of all columns. PCP was

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20

Poole, Alison E. "The functional response in pause-travel foraging birds." Thesis, University of Reading, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501361.

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The functional response (i.e. the relationship between the available density of an animal's prey and the animal's feeding rate) is typically modelled as some function of the behavioural parameters handling time and searching efficiency. An understanding of the functional responses of coastal wading birds (Charadriiformes) has allowed the use of behaviour-based models for prediction of the responses of these birds to environmental change. An understanding of the behavioural parameters underlying functional response models, should lead to the prediction of functional responses, and ultimately be

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21

Millington, Kerry. "Functional antigen-specific T cell responses to Mycobacterium tuberculosis infection." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437349.

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22

Taylor, Harriet Beverly. "Functional analysis of zebrafish innate immune responses to inflammatory signals." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4825.

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Injury, infection and tissue malfunction are triggers of inflammation which if not regulated may acquire new characteristics that result in pathological outcomes. Since innate immunity plays a key role in the resolution of acute inflammation knowledge of the regulation of this component of the host response is relevant to understanding processes in disease progression and therefore has potential clinical benefits. In this thesis I have applied zebrafish as a model organism to investigate the response of innate immune cells to qualitatively distinct inflammatory signals in the absence of adapti

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23

Brading, Penelope. "Functional analysis of Cf gene-dependent defence responses in tomato." Thesis, University of East Anglia, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389348.

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24

AlAdwani, Mohammad S. Kh F. Sh. "Understanding the effects of functional responses in ecological dynamical systems." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/121887.

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Thesis: S.M., Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2019<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 45-46).<br>The main purpose of incorporating functional responses into ecological models has been to add more realism and to help us to mechanistically explain the dynamics of species abundances in nature. Yet, their effects have not been widely understood, especially in multispecies systems. That is, it remains unclear whether the perceived benefits of adding functional responses are simply mathemati

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25

Drerup, Samuel A. "Functional Responses of Stream Communities to Acid Mine Drainage Remediation." Ohio University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1458822356.

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26

Jones, Dirk Andrew. "Functional neuroanatomy of blocking and inhibition of Pavlovian conditioning /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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27

Hart, Heledd. "Characterisation of responses of human auditory cortex to basic sound properties, as measured using fMRI." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272359.

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28

Bones, Robert. "Transfer of a topographically different function to an established functional equivalence class." Thesis, University of Ulster, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322417.

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29

Clements, Casey M. Ting Jenny P. Y. "Functional characterization of DJ-1 an oxidative response protein /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1218.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Mar. 26, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Microbiology and Immunology." Discipline: Microbiology and Immunology; Department/School: Medicine.

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30

Belanger, Scott E. "Functional and pathological responses of selected aquatic organisms to chrysotile asbestos." Diss., This resource online, 1985. http://scholar.lib.vt.edu/theses/available/etd-05222007-091305/.

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31

Rosignoli, Guglielmo. "Definition and Functional Profiling of HIV-1-Specific T-Cell Responses." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516975.

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32

Janicki, Claire Nicola. "Functional characterisation of HLA-A*68 restricted cytotoxic T cell responses." Thesis, University of Birmingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420860.

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33

Hansson, Björn. "Functional and molecular responses to concurrent exercise of the arm extensors." Thesis, Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-5304.

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Aim As most concurrent exercise studies to date have focused on lower limb muscles, this study explored the acute response to concurrent exercise of the arm extensors. Specifically, the effects of a preceding bout of aerobic exercise on the subsequent molecular and functional response to resistance exercise was explored. Method Eleven men performed unilateral consecutive bouts of arm extensor aerobic exercise (~40 min) and resistance exercise (4 sets of 7 reps) interspersed by 15 min recovery. The contralateral arm performed resistance exercise only. Peak concentric power was assessed duri

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34

Chen, Y. "Functional characterisation of tumour-specific T cell responses in pancreatic cancer." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1553215/.

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BACKGROUND AND AIMS: Pancreatic cancer (PC) has a poor prognosis and effective diagnostic tools and therapies are currently unavailable. This project has explored the role of T cell responses in PC patients as a potential therapy. METHODS: Serum mesothelin (MSLN) levels were tested in patients with pancreatic diseases. CD4+ and CD8+ T cell responses against full-length overlapping MSLN peptide pools were identified. CEA691, together with pre-chosen MSLN547 and WT1-126 were used to stimulate T cell lines from PC patients. Antigen-specific function and phenotype were characterised in the ex-vivo

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35

Bhavanasi, Dheeraj. "Role of Protein Kinase C delta in regulating platelet functional responses." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/283099.

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Physiology<br>Ph.D.<br>Platelets upon activation change their shape, aggregate and secrete alpha and dense granule contents among which ADP acts as a feedback activator. Different Protein Kinase C (PKCδ) isoforms have specific non-redundant roles in mediating platelet responses including secretion and thrombus formation. Protein Kinase C delta (PKCδ), a novel class of PKC isoform requiring diacyl glycerol but not calcium for its activation, has been shown to play an important role in several pathological processes. The aims of our current study are 1) to identify possible PKCδ specific substra

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36

Colbert, Crystal. "Functional Neural Toxicity and Endocrine Responses in Mice Following Naphthalene Exposure." Thesis, University of North Texas, 2010. https://digital.library.unt.edu/ark:/67531/metadc31529/.

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Polycyclic aromatic hydrocarbons (PAHs) are a well studied and diverse class of environmental toxicants. PAHs act via the aryl hydrocarbon receptor (AhR), and studies have suggested that PAHs may elicit neurological and estrogenic effects. Doses of PAHs between 50 to 150 ppm may elicit neurotoxicity in rodent models. The present study investigated the effects of naphthalene on in vivo steroidogenesis in Swiss Webster male mice, and in vitro neural function of Balb-C/ICR mice frontal cortex neurons. These data suggest that naphthalene may not elicit steroidogenic effects at concentrations ran

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37

Nogueira, Carla de Almeida. "Responses and mechanisms of a mediterranean grassland ecosystem to nutrient addition." Doctoral thesis, ISA/UL, 2018. http://hdl.handle.net/10400.5/17509.

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Doutoramento em Engenharia Florestal e dos Recursos Naturais - Instituto Superior de Agronomia<br>Global changes, resulting from anthropogenic activities, are increasing precipitation variability, drought and nutrient inputs into ecosystems. These global change drivers are expected to induce changes in grassland species richness and composition and functional structure and diversity which may in turn affect ecosystem functioning. This is particularly important for the Mediterranean basin, a climate change hotspot. Understanding how these changes affect grassland structure and functioning is cr

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38

Tsiftsoglou, Stefanos Alex. "Structural and functional studies on human complement factor I." Thesis, University of Oxford, 2005. http://ora.ox.ac.uk/objects/uuid:745ea729-07ae-4c15-be83-bb3bb0db99ff.

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The complement system is considered as the chief recognition and effector component of innate immunity; it is involved in inflammation and enhances the adaptive immune response. Factor I (fI) is a heterodimeric serine protease consisting of a heavy (HC) and a light-catalytic (LC) chain; it circulates in an active form regulating complement by selectively cleaving only C3b or C4b in the presence of a cofactor such as factor H (fH), CR1, MCP or C4bp. The cleavage of C3b occurs through a ternary complex formed between fI, C3b and a cofactor like fH and yields iC3b, a major opsonin. The structural

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39

Garcia, Anna Rosio. "A Cultural Adaptation of Functional Communication Training." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7623.

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Disparities in the use, quality, and outcomes of treatments, and the barriers that deter Hispanics from receiving healthcare services have been widely studied. Yet, similar efforts have been slow in the field of Applied Behavior Analysis (ABA). A way to decrease treatment disparities is to assess the influence of cultural variables in behavior analytic interventions, and to evaluate whether manipulations to these variables improve the overall results of the interventions among Hispanic families. During this study, we adapted functional communication training (FCT) to Hispanic parent’s cultural

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40

Wang, Liqun. "FUNCTIONAL CHARACTERIZATION OF UPD3 IN DROSOPHILA DEVELOPMENT." UKnowledge, 2008. http://uknowledge.uky.edu/gradschool_diss/637.

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The JAK/STAT pathway is a non-receptor tyrosine kinase signaling pathway that is well conserved and highly re-utilized in many mammalian and Drosophila developmental processes. Compared to dozens of ligands and receptors in mammalian JAK/STAT, Drosophila JAK/STAT pathway is simpler with one receptor and three ligands, Upd, Upd2 and Upd3, which have similar amino acid sequences. Previous literature shows that upd and upd2 exhibit the same dynamic striped expression pattern in embryos and have semi-redundant functions during embryogenesis. Do Upd and Upd3 also have redundant functions? To answer

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41

Macrae, Karewn Lesley. "Assessment of visual cortical responses to contrast with functional magnetic resonance imaging." Thesis, Royal Holloway, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538309.

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42

Payne, Sarah Jayne. "Functional responses mediated through G protein-coupled receptors of the vascular endothelium." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396043.

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43

Scase, Timothy John. "Blood platelet responses induced by adenosine 5'-diphosphate : functional and molecular studies." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624899.

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44

Ślebioda, Tomasz Jerzy. "Functional analysis of TL1A/DR3 interactions during T cell-mediated immune responses." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/196563/.

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Members of the tumour necrosis factor superfamily (TNFSF) are important regulators of inflammation and immunity. TL1A (TNFSF15), ligand for death receptor 3 (DR3), is the most recently discovered member of this superfamily and full understanding of its structure and the role in T cell-mediated immune responses is currently incomplete. DR3 expression is strongly up-regulated on activated T cells, although it also is present on resting CD4+ T cells, while the expression of TL1A is rapidly and transiently upregulated on activated cells of the immune system such as dendritic cells, monocytes and T

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45

Gajowa, Marta. "Synaptic and cellular mechanisms underlying functional responses in mouse primary visual cortex." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB125.

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L'élaboration de l'information dans le cerveau est basée sur les propriétés des neurones qui analysent leurs inputs et génèrent les potentiels d'actions, ainsi que sur un réseau synaptique d'une complexité beaucoup plus importante que ce que l'homme peut créer. Mon projet consiste à étudier ces éléments dans le cortex visuel de la souris, pour décrire comment ils permettent aux neurones de répondre à des caractéristiques du scène visuelle. Je développe des outils optogénétiques pour pouvoir stimuler des neurones individuels in vivo, ce qui va ensuite être intégré avec des mesures de leur répon

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46

Enright, Tracy. "Discovery of a Functional Ecdysone Response Element in Brugia malayi." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3496.

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The aim of this study was to determine whether functional ecdysone response elements (EcREs) exist within the genome of Brugia malayi, a parasitic nematode that causes lymphatic filariasis. The hypothesis that EcREs exist in B. malayi stemmed from previous demonstration of a functional ecdysone response system in B. malayi (Tzertzinis et al., 2010). Real-time PCR (qPCR) experiments were conducted to measure gene expression levels for twelve genes proximal to five putative EcREs in 20-OH ecdysone treated and untreated B. malayi embryos. Seven genes showed consistent upregulation with 20-OH ecdy

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47

Marques, Flávio Donizeti. "Multi-layer functional approximation of non-linear unsteady aerodynamic response." Thesis, University of Glasgow, 1997. http://theses.gla.ac.uk/2091/.

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Non-linear unsteady aerodynamic effects present major modelling difficulties in the analysis of aeroelastic response and in the subsequent design of appropriate controllers. As the direct use of the basic fluid mechanic equations is still not practical for aeroelastic applications, approximate models of the non-linear unsteady aerodynamic response are required. A rigorous mathematical framework, that can account for the complex non-linearities and time-history effects of the unsteady aerodynamic response, is provided by the use of functional representations. A recent development, based on func

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48

Haag, Shannon S. "Effects of response-independent stimulus delivery and functional communication training." Morgantown, W. Va. : [West Virginia University Libraries], 2002. http://etd.wvu.edu/templates/showETD.cfm?recnum=2613.

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Thesis (M.A.)--West Virginia University, 2002.<br>Title from document title page. Document formatted into pages; contains viii, 38 p. : ill. Includes abstract. Includes bibliographical references (p. 33-37).

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Robertson, Andrew Sutherland. "A functional characterization of the Drosophila immune response regulator, Necrotic." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615073.

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Doering, Jonathan Adam. "Sphingolipids Modulate the Inflammatory and Functional Response in mdx Mice." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/51220.

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Duchenne Muscular Dystrophy (DMD) is characterized by progressive muscle degeneration and a chronic inflammatory response. Sphingolipid metabolites are associated with the generation or perpetuation of low-grade chronic inflammation critical in atherosclerosis, obesity and cancer. Dietary sphingolipids, however, can suppress intestinal inflammation. We hypothesized that dietary sphingomyelin (SM) from bovine milk can modulate the inflammatory signature and improve muscle function in mdx mice, a model of DMD. C57BL10 (WT) and mdx mice were fed AIN 76A diet ± 0.1% SM for 7 weeks starting at age

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