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Artículos de revistas sobre el tema "Functionnal responses"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 14 de febrero de 2022

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1

Šumanović, Marina, Ivana Pozojević, Zlatko Mihaljević, Natalija Vučković, Valentina Dorić, and Marko Miliša. "Invertebrate functional responses to hydromorphological degradation in Mediterranean Croatian rivers." Fundamental and Applied Limnology 194, no. 3 (2021): 259–70. http://dx.doi.org/10.1127/fal/2020/1321.

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2

Mocochain, Ludovic, Georges Clauzon, and Jean-Yves Bigot. "The Ardèche endokarstic responses to the eustatic variations resulting from the Messinian salinity crisis." Bulletin de la Société Géologique de France 177, no. 1 (2006): 27–36. http://dx.doi.org/10.2113/177.1.27.

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Abstract The Messinian salinity crisis is typically recorded by evaporites in the abyssal plains of the Mediterranean Sea and by canyons incised into the Mediterranean margins and their hinterlands. However, the impacts of crisis on geomorphology and surface dynamics lasted, until canyons were filled by sediments in the Pliocene (fig. 2). In the mid-Rhône valley, the Ardeche Cretaceous carbonate platform is incised over 600 m by the Rhône Messinian canyon. The canyon thalweg is located – 236 m bsl (below sea level) in the borehole of Pierrelatte [Demarcq, 1960; fig. 1]. During the Pliocene,

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3

Sjödin, Henrik, Åke Brännström, and Göran Englund. "Space race functional responses." Proceedings of the Royal Society B: Biological Sciences 282, no. 1801 (2015): 20142121. http://dx.doi.org/10.1098/rspb.2014.2121.

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We derive functional responses under the assumption that predators and prey are engaged in a space race in which prey avoid patches with many predators and predators avoid patches with few or no prey. The resulting functional response models have a simple structure and include functions describing how the emigration of prey and predators depend on interspecific densities. As such, they provide a link between dispersal behaviours and community dynamics. The derived functional response is general but is here modelled in accordance with empirically documented emigration responses. We find that th

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4

Reynaga, María Celina, and Daniel Andrés Dos Santos. "Contrasting taxonomical and functional responses of stream invertebrates across space and time in a Neotropical basin." Fundamental and Applied Limnology 183, no. 2 (2013): 121–33. http://dx.doi.org/10.1127/1863-9135/2013/0501.

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5

Civil, Azem, Irma Rensink, Lucien A. Aarden, and Cornelis L. Verweij. "Functional Disparity of Distinct CD28 Response Elements toward Mitogenic Responses." Journal of Biological Chemistry 274, no. 48 (1999): 34369–74. http://dx.doi.org/10.1074/jbc.274.48.34369.

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6

Tanaka, Mutsumi, and Robin M. McAllen. "Functional topography of the dorsomedial hypothalamus." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 294, no. 2 (2008): R477—R486. http://dx.doi.org/10.1152/ajpregu.00633.2007.

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The dorsomedial hypothalamus (DMH) has been proposed to play key roles in both the defense reaction to acute stress and in the thermoregulatory response to cold. We reasoned that the autonomic/respiratory motor patterns of these responses would be mediated by at least partly distinct DMH neuron populations. To test this, we made simultaneous recordings of phrenic nerve and plantar cutaneous vasoconstrictor (CVC) activity in 14 vagotomized, ventilated, urethane-anesthetized rats. Microinjections of d,l-homocysteic acid (DLH; 15 nl, 50 mM) were used to cause localized, short-lasting (<1 min)

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7

Sohrabi, F., P. Shishehbor, M. Saber, and M. S. Mosaddegh. "Effects of buprofezin and imidacloprid on the functional response of Eretmocerus mundus Mercet." Plant Protection Science 50, No. 3 (2014): 145–50. http://dx.doi.org/10.17221/64/2012-pps.

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Eretmocerus mundus Mercet is one of the key natural enemies of Bemisia tabaci (Gennadius). In this study, the sublethal effects of LC<sub>25</sub> of imidacloprid and field-recommended concentration of buprofezin on the functional response of E. mundus to different densities of second instar B. tabaci nymphs were evaluated. The results revealed a type III functional response in the control and imidacloprid treatment. The type III functional response was altered into a type II by buprofezin. Although imidacloprid did not alter the type of functional response of E. mundus compared to

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8

Williams, F. M., and Steven A. Juliano. "Functional Responses Revisited." Environmental Entomology 25, no. 3 (1996): 549–50. http://dx.doi.org/10.1093/ee/25.3.549.

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9

Voychuk, S. I., and E. N. Gromozova. "The Functional Role of PPN1 and PPX1 Polyphosphatases under Stresses Action and for Adaptive Response Development." Mikrobiolohichnyi Zhurnal 82, no. 1 (2020): 3–12. http://dx.doi.org/10.15407/microbiolj82.01.003.

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10

Jam, Neda Amini, and Moosa Saber. "Sublethal effects of imidacloprid and pymetrozine on the functional response of the aphid parasitoid, Lysiphlebus fabarum." Entomologia Generalis 38, no. 2 (2018): 173–90. http://dx.doi.org/10.1127/entomologia/2018/0734.

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11

Pichlová, Radka, and Jacobus Vijverberg. "A laboratory study of functional response of Leptodora kindtii to some cladoceran species and copepod nauplii." Fundamental and Applied Limnology 150, no. 4 (2001): 529–44. http://dx.doi.org/10.1127/archiv-hydrobiol/150/2001/529.

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12

García, Carlos, Victoria Ávila, Humberto Quesada, and Armando Caballero. "Are transcriptional responses to inbreeding a functional response to alleviate inbreeding depression?" Fly 7, no. 1 (2013): 8–12. http://dx.doi.org/10.4161/fly.22559.

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13

Fisher, Wayne W., Brian D. Greer, Angie C. Querim, and Nicole DeRosa. "Decreasing excessive functional communication responses while treating destructive behavior using response restriction." Research in Developmental Disabilities 35, no. 11 (2014): 2614–23. http://dx.doi.org/10.1016/j.ridd.2014.06.024.

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14

Frumkes, Thomas E., and Ralph Nelson. "Functional role of GABA in cat retina: I. Effects of GABAA agonists." Visual Neuroscience 12, no. 4 (1995): 641–50. http://dx.doi.org/10.1017/s0952523800008932.

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AbstractPutative GABAergic mechanisms were studied in perfused cat retina by means of intracellular recording and application of GABA and the GABAA agonists δ-amino valeric acid (dAVA), muscimol, and THIP. In contrast to results reported previously for cold-blooded vertebrates, introduction of 20 mM GABA into the superfusate had no influence upon the response properties of cat retinal horizontal cells (HCs). In common with results reported in cold-blooded vertebrates, introduction of the GABAA agonists dAVA (2–12 mM) and THIP or muscimol (0.2–1 mM) had four consistent reversible influences upo

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15

Görling, Andreas, Andrey Ipatov, Andreas W. Götz, and Andreas Heßelmann. "Density-Functional Theory with Orbital-Dependent Functionals: Exact-exchange Kohn-Sham and Density-Functional Response Methods." Zeitschrift für Physikalische Chemie 224, no. 3-4 (2010): 325–42. http://dx.doi.org/10.1524/zpch.2010.6108.

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16

Dunn, Robert P., and Kevin A. Hovel. "Predator type influences the frequency of functional responses to prey in marine habitats." Biology Letters 16, no. 1 (2020): 20190758. http://dx.doi.org/10.1098/rsbl.2019.0758.

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The functional response of a consumer to a gradient of resource density is a widespread and consistent framework used to quantify the importance of consumption to population dynamics and stability. Within benthic marine ecosystems, both crustaceans and fishes can provide strong top-down pressure on prey populations. Taxon-specific differences in biomechanics or habitat use, among other factors, may lead to variable functional response forms or parameter values (attack rate, handling time). Based on a review of 189 individual functional response fits, we find that these predator guilds differ i

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17

AGRAWAL, RASHMI, DEBALDEV JANA, RANJIT KUMAR UPADHYAY, and V. SREE HARI RAO. "DYNAMIC RELATIONSHIP BETWEEN THE MUTUAL INTERFERENCE AND GESTATION DELAYS OF A HYBRID TRITROPHIC FOOD CHAIN MODEL." ANZIAM Journal 59, no. 3 (2018): 370–401. http://dx.doi.org/10.1017/s144618111700044x.

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We have proposed a three-species hybrid food chain model with multiple time delays. The interaction between the prey and the middle predator follows Holling type (HT) II functional response, while the interaction between the top predator and its only food, the middle predator, is taken as a general functional response with the mutual interference schemes, such as Crowley–Martin (CM), Beddington–DeAngelis (BD) and Hassell–Varley (HV) functional responses. We analyse the model system which employs HT II and CM functional responses, and discuss the local and global stability analyses of the coexi

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18

Hikosaka, O., M. Sakamoto, and S. Usui. "Functional properties of monkey caudate neurons. II. Visual and auditory responses." Journal of Neurophysiology 61, no. 4 (1989): 799–813. http://dx.doi.org/10.1152/jn.1989.61.4.799.

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1. Visual responses of caudate neurons were studied in monkeys trained to fixate on a small spot of light. A visual stimulus (another spot of light) was presented in various contexts of behavior using different behavioral paradigms. Visual receptive fields were usually large and centered on the contralateral hemifield. Among 217 neurons with visual responses, 184 were further classified into subtypes. 2. Visual responses in 64 neurons were not modulated by changing the paradigms (unconditional visual responses). In the other neurons, visual responses were dependent on the behavioral contexts i

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19

Mitchel, R. E. J. "Radiation Risk Prediction and Genetics: The Influence of the TP53 Gene in vivo." Dose-Response 3, no. 4 (2005): dose—response.0. http://dx.doi.org/10.2203/dose-response.003.04.007.

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Risk prediction and dose limits for human radiation exposure are based on the assumption that risk is proportional to total dose. However, there is concern about the appropriateness of those limits for people who may be genetically cancer prone. The TP53 gene product functions in regulatory pathways for DNA repair, cell cycle checkpoints and apoptosis, processes critical in determining ionizing radiation risk for both carcinogenesis and teratogenesis. Mice that are deficient in TP53 function are cancer prone. This review examines the influence of variations in TP53 gene activity on cancer and

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20

Billiard, Sylvain, Vincent Bansaye, and J. R. Chazottes. "Rejuvenating functional responses with renewal theory." Journal of The Royal Society Interface 15, no. 146 (2018): 20180239. http://dx.doi.org/10.1098/rsif.2018.0239.

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Functional responses are widely used to describe interactions and resource exchange between individuals in ecology. The form given to functional responses dramatically affects the dynamics and stability of populations and communities. Despite their importance, functional responses are generally considered with a phenomenological approach, without clear mechanistic justifications from individual traits and behaviours. Here, we develop a bottom-up stochastic framework grounded in renewal theory that shows how functional responses emerge from the level of the individuals through the decomposition

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21

Khan, Muhammad Hamayoon, Niaz Hussain Khuhro, Muhammad Awais, Raza Muhammad Memon, and Muhammad Usman Asif. "Functional response of the pupal parasitoid, Dirhinus giffardii towards two fruit fly species, Bactrocera zonata and B. cucurbitae." Entomologia Generalis 40, no. 1 (2020): 87–95. http://dx.doi.org/10.1127/entomologia/2020/0878.

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22

Telli, Murat, Donna M. Gordon, and Ercan Selçuk Ünlü. "Transcriptional response and functional target analyses of miRNA and mRNA to planktivorous fish kairomone exposure in Daphnia magna." Fundamental and Applied Limnology 195, no. 1 (2021): 73–84. http://dx.doi.org/10.1127/fal/2021/1386.

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23

Kolawole, Elizabeth M., Tracey J. Lamb, and Brian D. Evavold. "Relationship of 2D Affinity to T Cell Functional Outcomes." International Journal of Molecular Sciences 21, no. 21 (2020): 7969. http://dx.doi.org/10.3390/ijms21217969.

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T cells are critical for a functioning adaptive immune response and a strong correlation exists between T cell responses and T cell receptor (TCR): peptide-loaded MHC (pMHC) binding. Studies that utilize pMHC tetramer, multimers, and assays of three-dimensional (3D) affinity have provided advancements in our understanding of T cell responses across different diseases. However, these technologies focus on higher affinity and avidity T cells while missing the lower affinity responders. Lower affinity TCRs in expanded polyclonal populations almost always constitute a significant proportion of the

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24

Lippton, H. L., T. A. Hauth, G. A. Cohen, and A. L. Hyman. "Functional evidence for different endothelin receptors in the lung." Journal of Applied Physiology 75, no. 1 (1993): 38–48. http://dx.doi.org/10.1152/jappl.1993.75.1.38.

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The present study was undertaken to compare and contrast the characteristics of the pulmonary and systemic vascular responses to endothelin (ET) isoforms in the intact spontaneously breathing cat under conditions of constant pulmonary blood flow and left atrial pressure. When pulmonary vasomotor tone (PVT) was actively increased by intralobar infusion of U-46619, intralobar arterial bolus injections of 1 microgram ET-1, 1 microgram ET-2, or 3 micrograms ET-3 markedly decreased lobar arterial pressure, systemic arterial pressure, and systemic vascular resistance. After seven repeated injections

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25

Stiernman, Lars Jonasson, Filip Grill, Andreas Hahn, et al. "Dissociations between glucose metabolism and blood oxygenation in the human default mode network revealed by simultaneous PET-fMRI." Proceedings of the National Academy of Sciences 118, no. 27 (2021): e2021913118. http://dx.doi.org/10.1073/pnas.2021913118.

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The finding of reduced functional MRI (fMRI) activity in the default mode network (DMN) during externally focused cognitive control has been highly influential to our understanding of human brain function. However, these negative fMRI responses, measured as relative decreases in the blood-oxygenation-level–dependent (BOLD) response between rest and task, have also prompted major questions of interpretation. Using hybrid functional positron emission tomography (PET)-MRI, this study shows that task-positive and -negative BOLD responses do not reflect antagonistic patterns of synaptic metabolism.

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26

Benatia, David, Marine Carrasco, and Jean-Pierre Florens. "Functional linear regression with functional response." Journal of Econometrics 201, no. 2 (2017): 269–91. http://dx.doi.org/10.1016/j.jeconom.2017.08.008.

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27

Bressendorff, Berith B., and Søren Toft. "Dome-shaped functional response induced by nutrient imbalance of the prey." Biology Letters 7, no. 4 (2011): 517–20. http://dx.doi.org/10.1098/rsbl.2011.0103.

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Nutritional ecological theory predicts that predators should adjust prey capture and consumption rates depending on the prey's nutritional composition. This would affect the predator's functional response, at least at high prey densities, i.e. near predator satiation. Using a simple fruitfly-wolf spider laboratory system in Petri dishes, we found that functional responses changed from day to day over a 7 day period. After 1 to 2 days of feeding, dome-shaped functional responses (i.e. reduced predation at highest prey densities) appeared in spiders fed nutritionally imbalanced prey, compared wi

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28

Greenberg, Paul A., and Fraser A. W. Wilson. "Functional Stability of Dorsolateral Prefrontal Neurons." Journal of Neurophysiology 92, no. 2 (2004): 1042–55. http://dx.doi.org/10.1152/jn.00062.2004.

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Stable multiday recordings from the dorsolateral prefrontal cortex of 2 monkeys performing 2 Go/NoGo visual-discrimination tasks (one requiring well-learned responses, the other requiring learning) demonstrate that the majority of prefrontal neurons were “functionally stable”. Recordings were made using a series of removable microdrives, each implanted for 3–6 mo, housing independently mobile electrodes. Action potential waveforms of 94 neurons were stable over 2–9 days; 66/94 (70%) of these cells responded each day, 22/94 (23%) never responded significantly, and 6/94 (6%) responded one day bu

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29

Marasanov, Aleksandr V., and E. A. Valtseva. "PHENOMICS. ETIOLOGY OF HUMAN ORGANISM FUNCTIONAL STATES UNDER THE EFFECT OF ENVIRONMENTAL FACTORS." Hygiene and sanitation 96, no. 10 (2019): 1004–9. http://dx.doi.org/10.18821/0016-9900-2017-96-10-1004-1009.

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The article based on the analysis and synthesis of scientific works regarding the theory of adaptation offers the detailed description of the development of functional responses of the human organism under the impact of environmental factors. Three types of responses are considered: nonspecific reaction of human organism, specific response of the human organism and response of the human organism to specificity of a factor. The article is focused on form for the rationale for specific response of the human organism. It is due to the fact that in scientific literature in the capacity of such res

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30

Palamara, Gian Marco, José A. Capitán, and David Alonso. "The Stochastic Nature of Functional Responses." Entropy 23, no. 5 (2021): 575. http://dx.doi.org/10.3390/e23050575.

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Functional responses are non-linear functions commonly used to describe the variation in the rate of consumption of resources by a consumer. They have been widely used in both theoretical and empirical studies, but a comprehensive understanding of their parameters at different levels of description remains elusive. Here, by depicting consumers and resources as stochastic systems of interacting particles, we present a minimal set of reactions for consumer resource dynamics. We rigorously derived the corresponding system of ODEs, from which we obtained via asymptotic expansions classical 2D cons

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31

Schmitz, OJ. "Functional responses of optimal consumers and the potential for regulation of resource populations." Wildlife Research 22, no. 1 (1995): 101. http://dx.doi.org/10.1071/wr9950101.

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A central issue in studies of consumer-resource interactions is whether consumers regulate resource dynamics. One condition for regulation is that consumption rate of a resource increases positively with increasing resource density, that is, that the consumer's functional response must be positively density dependent. Many mammalian consumers exhibit density-independent or inversely density-dependent functional responses, suggesting that regulation will not occur. However, most studies measure functional responses for a single consumer and resource species in specific feeding trials. Many real

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32

Mure, Ludovic S., Frans Vinberg, Anne Hanneken, and Satchidananda Panda. "Functional diversity of human intrinsically photosensitive retinal ganglion cells." Science 366, no. 6470 (2019): 1251–55. http://dx.doi.org/10.1126/science.aaz0898.

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Intrinsically photosensitive retinal ganglion cells (ipRGCs) are a subset of cells that participate in image-forming and non–image-forming visual responses. Although both functional and morphological subtypes of ipRGCs have been described in rodents, parallel functional subtypes have not been identified in primate or human retinas. In this study, we used a human organ donor preparation method to measure human ipRGCs’ photoresponses. We discovered three functional ipRGC subtypes with distinct sensitivities and responses to light. The response of one ipRGC subtype appeared to depend on exogenous

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33

Garzon Medina, Carolina, Sara Catalina Forero Molina, Wilmer Darío Pineda Ríos, and Alejandro Lopera Marín. "Influencia de los anuncios publicitarios en redes sociales en la respuesta emocional y la intención de compra de bebidas lácteas funcionales." Interdisciplinaria Revista de Psicología y Ciencias Afines 38, no. 2 (2021): 167–82. http://dx.doi.org/10.16888/interd.2021.38.2.11.

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En la actualidad, la salud, el bienestar y la estética son relevantes para los consumidores y se ven inmersos en la publicidad a través de las redes sociales. El presente estudio tiene como objetivo determinar la relación entre los anuncios publicitarios vistos a través de redes sociales, la respuesta emocional y la intención de compra de bebidas lácteas funcionales en jóvenes universitarios entre 18 y 35 años de la ciudad de Bogotá, Colombia. La metodología es de tipo cuantitativo, a través de un diseño cuasiexperimental de un grupo control, con medición pretest/postest, a partir de la aplica

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34

Li, Chuanfu, Jun Yang, Jinbo Sun, et al. "Brain Responses to Acupuncture Are Probably Dependent on the Brain Functional Status." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–14. http://dx.doi.org/10.1155/2013/175278.

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In recent years, neuroimaging studies of acupuncture have explored extensive aspects of brain responses to acupuncture in finding its underlying mechanisms. Most of these studies have been performed on healthy adults. Only a few studies have been performed on patients with diseases. Brain responses to acupuncture in patients with the same disease at different pathological stages have not been explored, although it may be more important and helpful in uncovering its underlying mechanisms. In the present study, we used fMRI to compare brain responses to acupuncture in patients with Bell’s palsy

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35

Kastner, Sabine, Daniel H. O'Connor, Miki M. Fukui, Hilda M. Fehd, Uwe Herwig, and Mark A. Pinsk. "Functional Imaging of the Human Lateral Geniculate Nucleus and Pulvinar." Journal of Neurophysiology 91, no. 1 (2004): 438–48. http://dx.doi.org/10.1152/jn.00553.2003.

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In the human brain, little is known about the functional anatomy and response properties of subcortical nuclei containing visual maps such as the lateral geniculate nucleus (LGN) and the pulvinar. Using functional magnetic resonance imaging (fMRI) at 3 tesla (T), collective responses of neural populations in the LGN were measured as a function of stimulus contrast and flicker reversal rate and compared with those obtained in visual cortex. Flickering checkerboard stimuli presented in alternation to the right and left hemifields reliably activated the LGN. The peak of the LGN activation was fou

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Yi, Young-Su, Young-Jin Son, Chongsuk Ryou, Gi-Ho Sung, Jong-Hoon Kim, and Jae Youl Cho. "Functional Roles of Syk in Macrophage-Mediated Inflammatory Responses." Mediators of Inflammation 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/270302.

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Inflammation is a series of complex biological responses to protect the host from pathogen invasion. Chronic inflammation is considered a major cause of diseases, such as various types of inflammatory/autoimmune diseases and cancers. Spleen tyrosine kinase (Syk) was initially found to be highly expressed in hematopoietic cells and has been known to play crucial roles in adaptive immune responses. However, recent studies have reported that Syk is also involved in other biological functions, especially in innate immune responses. Although Syk has been extensively studied in adaptive immune respo

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Urban, Mark C., Nicole A. Freidenfelds, and Jonathan L. Richardson. "Microgeographic divergence of functional responses among salamanders under antagonistic selection from apex predators." Proceedings of the Royal Society B: Biological Sciences 287, no. 1938 (2020): 20201665. http://dx.doi.org/10.1098/rspb.2020.1665.

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A predator's functional response determines predator–prey interactions by describing the relationship between the number of prey available and the number eaten. Its shape and parameters fundamentally govern the dynamic equilibrium of predator–prey interactions and their joint abundances. Yet, estimates of these key parameters generally assume stasis in space and time and ignore the potential for local adaptation to alter feeding responses and the stability of trophic dynamics. Here, we evaluate if functional responses diverge among populations of spotted salamander ( Ambystoma maculatum ) larv

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38

Rabindran, S. K., M. Danielsen, and M. R. Stallcup. "Glucocorticoid-resistant lymphoma cell variants that contain functional glucocorticoid receptors." Molecular and Cellular Biology 7, no. 12 (1987): 4211–17. http://dx.doi.org/10.1128/mcb.7.12.4211.

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A mouse T-lymphosarcoma cell line stably infected with mouse mammary tumor virus (MMTV) was used as the parent line for a genetic analysis of two glucocorticoid hormone responses, hormone-induced cytolysis and stimulation of viral gene expression. Variants were selected for survival and elevated expression of MMTV proteins in the presence of the steroid. The MMTV marker provided a sensitive test for glucocorticoid receptor (GR) function in the hormone-resistant variants. This strategy resulted in the isolation of two novel types of hormone-resistant variants. One type of variant with only abou

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39

Rabindran, S. K., M. Danielsen, and M. R. Stallcup. "Glucocorticoid-resistant lymphoma cell variants that contain functional glucocorticoid receptors." Molecular and Cellular Biology 7, no. 12 (1987): 4211–17. http://dx.doi.org/10.1128/mcb.7.12.4211-4217.1987.

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A mouse T-lymphosarcoma cell line stably infected with mouse mammary tumor virus (MMTV) was used as the parent line for a genetic analysis of two glucocorticoid hormone responses, hormone-induced cytolysis and stimulation of viral gene expression. Variants were selected for survival and elevated expression of MMTV proteins in the presence of the steroid. The MMTV marker provided a sensitive test for glucocorticoid receptor (GR) function in the hormone-resistant variants. This strategy resulted in the isolation of two novel types of hormone-resistant variants. One type of variant with only abou

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40

Cacuci, Dan Gabriel. "Fourth-Order Comprehensive Adjoint Sensitivity Analysis (4th-CASAM) of Response-Coupled Linear Forward/Adjoint Systems: I. Theoretical Framework." Energies 14, no. 11 (2021): 3335. http://dx.doi.org/10.3390/en14113335.

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The most general quantities of interest (called “responses”) produced by the computational model of a linear physical system can depend on both the forward and adjoint state functions that describe the respective system. This work presents the Fourth-Order Comprehensive Adjoint Sensitivity Analysis Methodology (4th-CASAM) for linear systems, which enables the efficient computation of the exact expressions of the 1st-, 2nd-, 3rd- and 4th-order sensitivities of a generic system response, which can depend on both the forward and adjoint state functions, with respect to all of the parameters under

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41

Blood, Anne J., Nader Pouratian, and Arthur W. Toga. "Temporally Staggered Forelimb Stimulation Modulates Barrel Cortex Optical Intrinsic Signal Responses to Whisker Stimulation." Journal of Neurophysiology 88, no. 1 (2002): 422–37. http://dx.doi.org/10.1152/jn.2002.88.1.422.

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Characterization of neurovascular relationships is critical to accurate interpretation of functional neuroimaging data. We have previously observed spatial uncoupling of optical intrinsic signal imaging (OIS) and evoked potential (EP) responses in rodent barrel cortex following simultaneous whisker and forelimb stimulation, leading to changes in OIS response magnitude. To further test the hypothesis that this uncoupling may have resulted from “passive” overspill of perfusion-related responses between functional regions, we conducted the present study using temporally staggered rather than simu

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Moulton, E. A., M. L. Keaser, R. P. Gullapalli, and J. D. Greenspan. "Regional Intensive and Temporal Patterns of Functional MRI Activation Distinguishing Noxious and Innocuous Contact Heat." Journal of Neurophysiology 93, no. 4 (2005): 2183–93. http://dx.doi.org/10.1152/jn.01025.2004.

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Cortical responses to painful and nonpainful heat were measured using functional magnetic resonance imaging (fMRI) region of interest analysis (ROI) of primary somatosensory cortex (S1), secondary somatosensory cortex (S2), anterior cingulate (ACC), supplementary motor area (SMA), insula, and inferior frontal gyrus (IFG). Previous studies indicated that innocuous and noxious stimuli of different modalities produce responses with different time courses in S1 and S2. The aim of this study was to 1) determine whether temporally distinct nociceptive blood oxygen level–dependent (BOLD) responses ar

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Kannurpatti, Sridhar S., and Bharat B. Biswal. "Negative Functional Response to Sensory Stimulation and its Origins." Journal of Cerebral Blood Flow & Metabolism 24, no. 6 (2004): 703–12. http://dx.doi.org/10.1097/01.wcb.0000121232.04853.46.

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Functional imaging studies typically give prominence to positive responses. However, negative changes that accompany activation-induced positive responses are not yet clearly understood. The authors investigated the origin of sustained negative CBF responses that accompanied positive CBF changes. Measurements were made in the rat somatosensory cortex in response to whisker stimulation using laser-Doppler imaging. Flux images indicative of CBF were obtained at rest and during whisker stimulation with a spatial resolution of 200 μm. Large and intermediate blood vessels in the cortical surface ex

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Baker, Wesley B., Zhenghui Sun, Teruyuki Hiraki, et al. "Neurovascular Coupling Varies with Level of Global Cerebral Ischemia in a Rat Model." Journal of Cerebral Blood Flow & Metabolism 33, no. 1 (2012): 97–105. http://dx.doi.org/10.1038/jcbfm.2012.137.

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In this study, cerebral blood flow, oxygenation, metabolic, and electrical functional responses to forepaw stimulation were monitored in rats at different levels of global cerebral ischemia from mild to severe. Laser speckle contrast imaging and optical imaging of intrinsic signals were used to measure changes in blood flow and oxygenation, respectively, along with a compartmental model to calculate changes in oxygen metabolism from these measured changes. To characterize the electrical response to functional stimulation, we measured somatosensory evoked potentials (SEPs). Global graded ischem

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Cox, Louis Anthony (Tony). "A Model of Cytotoxic Dose-Response Nonlinearities Arising from Adaptive Cell Inventory Management in Tissues." Dose-Response 3, no. 4 (2005): dose—response.0. http://dx.doi.org/10.2203/dose-response.003.04.005.

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Why do low-level exposures to environmental toxins often elicit over-compensating responses that reduce risk to an organism? Conversely, if these responses improve health, why wait for an environmental challenge to trigger them? This paper presents a mathematical modeling framework that addresses both questions using the principle that evolution favors tissues that hedge their bets against uncertain environmental challenges. We consider a tissue composed of differentiated cells performing essential functions (e.g., lung tissue, bone marrow, etc.). The tissue seeks to maintain adequate supplies

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Christopher, Kenneth, Charlotte M. McKee, Thomas F. Mueller, and David L. Perkins. "Functional genomics of immune responses." Immunology and Allergy Clinics of North America 22, no. 4 (2002): 891–910. http://dx.doi.org/10.1016/s0889-8561(02)00013-9.

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Barnichon, Regis, and Christian Matthes. "Functional Approximation of Impulse Responses." Journal of Monetary Economics 99 (November 2018): 41–55. http://dx.doi.org/10.1016/j.jmoneco.2018.04.013.

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Ghaemmaghami, Mahshid, Gregory P. Hanley, Joshua Jessel, and Robin Landa. "Shaping complex functional communication responses." Journal of Applied Behavior Analysis 51, no. 3 (2018): 502–20. http://dx.doi.org/10.1002/jaba.468.

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Okuyama, Toshinori. "Flexible components of functional responses." Journal of Animal Ecology 81, no. 1 (2011): 185–89. http://dx.doi.org/10.1111/j.1365-2656.2011.01876.x.

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Ances, Beau M., Joel H. Greenberg, and John A. Detre. "Effects of Variations in Interstimulus Interval on Activation–Flow Coupling Response and Somatosensory Evoked Potentials with Forepaw Stimulation in the Rat." Journal of Cerebral Blood Flow & Metabolism 20, no. 2 (2000): 290–97. http://dx.doi.org/10.1097/00004647-200002000-00010.

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In functional neuroimaging studies, the hemodynamic response to functional activation is used as a surrogate marker for neuronal activity, typically in response to task paradigms that use periodic stimuli. With use of a model system of electrical forepaw stimulation in rats (n = 14) with laser-Doppler (LD) monitoring of cerebral blood flow (CBF) changes in the somatosensory cortex, the effects of variations in the interstimulus interval (ISI) on the hemodynamic response to periodic stimuli were examined. A characteristic peak flow response was seen for 4-second stimuli and a peak and plateau r

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