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Tesis sobre el tema "Graves' disease"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 26 de julio de 2025

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1

Barrett, Kerry. "Studies on the development of a mouse model of Graves' disease /." Internet access available to MUN users only, 2003. http://collections.mun.ca/u?/theses,156073.

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Gilbert, Jacqueline Ann. "Thyrotropin receptor autoantibodies in hyperthyroid Graves' disease." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429153.

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Heward, Joanne Marie. "Genetic susceptibility to the development of Graves' disease." Thesis, University of Birmingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343429.

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4

Asghar, Muhammad Suhail. "Cloning and analysis of autoantibodies in autoimmune thryroid disease." Thesis, University of Sheffield, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267123.

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5

Mulcahy, Anthony Francis. "The molecular cloning and characterisation of autoantigens." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242453.

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6

Hargreaves, Chantal. "The evolution of the autoantibody response in Graves' disease." Thesis, King's College London (University of London), 2013. https://kclpure.kcl.ac.uk/portal/en/theses/the-evolution-of-the-autoantibody-response-in-graves-disease(b12a689c-e5d7-4478-b81a-40daa8b34a97).html.

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Graves’ disease (GD) is an antibody-mediated autoimmune disease caused by thyroid stimulating antibodies (TSAbs) activating the thyrotropin receptor (TSHR). Both genetic and environmental factors contribute to pathogenesis and one such factor is the infectious agent, Yersinia enterocolitica. Two high affinity TSAbs, (KSAbl, lgG2t>/K; KSAb2, IgGaa/K), developed from an experimental murine model of GD, share common germline Ig genes and thus are derived from the same precursor B cell clone which diversified through somatic hypermutation. The shared germline genes were expressed as recombinant (r
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7

Saijo(Kim), Misa. "Generation of transgenic animal model of hyperthyroid Graves' disease." Kyoto University, 2004. http://hdl.handle.net/2433/147457.

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Kashanian, Gholam Reza Moshtaghi. "Role of bioactive peptides in autoimmune thyroid disease." Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318115.

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9

YOSHIOKA, SHUKO, YASUHIKO SUZUKI, YUKO SHIMIZU, et al. "A CASE OF AUTOIMMUNE HEPATITIS WITH GRAVES’ DISEASE TREATED BY PROPYLTHIOURACIL." Nagoya University School of Medicine, 2011. http://hdl.handle.net/2237/15363.

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Santos, Allan de Oliveira. "Avaliação da captação tireoidiana de sestamibi-99m Tc em individuos eutireoidianos e em portadores de doença tireoidiana auto-imune." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310090.

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Orientadores: Celso Dario Ramos, Denise Engelbrecht Zantut-Wittmann<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-06T23:42:28Z (GMT). No. of bitstreams: 1 Santos_AllandeOliveira_D.pdf: 19625404 bytes, checksum: 8c30ac3124c78a37e36fb80042a4ab61 (MD5) Previous issue date: 2006<br>Resumo: Introdução: Múltiplos radioisótopos estão disponíveis para avaliar pacientes com doença tireoidiana. O iodeto radioativo e o pertecnetato-99m Tc são os traçadores mais utilizados com esta finalidade. Outros radiofármacos, como por
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YAMAMOTO, MASAHIRO, AKITOSHI KAWAKUBO, and TOSHIKI MANO. "Glucose and Insulin Metabolism in Patients with Hyperthyroidism Due to Graves' Disease." Nagoya University School of Medicine, 1994. http://hdl.handle.net/2237/15939.

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12

Hsieh, Albert. "A Translational Exploration of Graves’ Disease: Clinical, Laboratory and Animal Studies." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20599.

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Graves’ disease (GD) is an autoimmune disorder, mediated by the thyroid stimulating hormone (TSH) receptor antibody (TRAb). This bioactive antibody causes thyrotoxicosis and it may contribute to extra-thyroidal manifestations, particularly Graves’ ophthalmopathy and pre-tibial myxoedema. Despite its pathogenic role, TRAb is not universally measured to confirm the diagnosis of GD in a hyperthyroid patient with a non-pathognomonic presentation. The modern TRAb assays only quantitate the serum TRAb level without determining its function. Furthermore, the mainstream animal models of GD focus upon
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13

Edmunds, Matthew Ross. "Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/6065/.

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Thyroid-Associated Ophthalmopathy (TAO) is a debilitating inflammatory condition of the orbit occurring in 30-50% of Graves' Disease (GD) patients. It is not currently possible to predict which GD patients will develop TAO or the severity of their eventual ophthalmic manifestations. The aim of this thesis was to evaluate novel biomarkers for this purpose. I developed two immunoassays to detect serum antibodies to insulin-like growth factor-1 receptor (IGF-lR-Ab) in GD, TAO and healthy controls (HC). Assays were validated to measure commercial monoclonal IGF-lR-Ab but no study group differences
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14

Ewins, David Laurence. "Characterisation of autoantigenic epitopes on thyroid peroxidase recognised by antibodies and T lymphocytes in autoimmune thryroid disease." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240770.

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15

Olenovych, O. A. "Assessment of risk of allergic disorders development in case of Graves’ disease." Thesis, Актальні питання тиреоїдології: матеріали науково-практичної інтернет-конференції. – (Чернівці, 9-10 червня 2014 р.). – Чернівці: Медуніверситет, 2014. – С.66, 2014. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/10777.

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16

Andrade, Vânia Araújo. "Efeito do metimazol na eficácia do tratamento com iodo radioativo e nos níveis séricos do TRAb na doença de Graves." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2003. http://hdl.handle.net/10183/8499.

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O hipertireoidismo da doença de Graves é a forma mais comum de hipertireoidismo em pacientes entre 20-50 anos. Três abordagens terapêuticas são atualmente utilizadas, drogas antitireoidiana, cirurgia e iodo radioativo (131I). O iodo radioativo tem sido cada vez mais aceito como primeira escolha terapêutica, porque é um tratamento seguro, definitivo e de fácil administração. O risco de piora do quadro de tireotoxicose após administração do 131I, os fatores prognósticos de falência e o cálculo da dose administrada têm sido alguns dos aspectos discutidos na literatura recentemente, e constituem o
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17

AL, ANSARI FARAH. "Studies of the autoimmune reactions in the thyroid and peripheral blood of patients with Graves ophthalmopathy with an emphasis on the roles of the CD8+ T cells and the eye muscle antigen calsequestrin." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/19602.

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The mechanism for the association of autoimmunity in the thyroid and orbit in Graves ophthalmopathy (GO) is unclear but is most likely a result of autoimmune attack against a thyroid and orbital tissue shared antigen. In this thesis, a novel approach was taken in relation to the correlation between parameters of thyroid autoimmunity, changes in the peripheral blood T cell populations and the presence of ophthalmopathy in patients with Graves’ disease. Enzyme digestion, flow cytometry, cell culture, cell proliferation assays and enzyme linked immunosorbent assay (ELISA) were used to study % th
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18

Santos, Roberto Bernardo dos. "Perfil genetico de risco para doença de Graves e para a oftalmopatia de Graves em uma população brasileira." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310274.

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Orientador: Laura Sterian Ward<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-13T00:14:50Z (GMT). No. of bitstreams: 1 Santos_RobertoBernardodos_D.pdf: 2009971 bytes, checksum: 0cf90a1782f718e3576f9172bd717ecf (MD5) Previous issue date: 2009<br>Resumo: A Doença de Graves é um processo imunológico em que a combinação de fatores genéticos e ambientais é fundamental. Vários genes têm sido propostos como envolvidos no desenvolvimento da doença, particularmente os genes do sistema HLA e os polimorfismos do gene CTLA-4.
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19

Merrill, Steven J. "A system dynamics approach for the development of a patient-specific protocol for radioiodine treatment of Graves' Disease." Amherst, Mass. : University of Massachusetts Amherst, 2009. http://scholarworks.umass.edu/theses/260/.

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Thesis (M.S.M.E.)--University of Massachusetts Amherst, 2009.<br>Open access. "This protocol is the basis of an ongoing pilot study in conjunction with Cooley Dickinson Hospital, Northampton, MA."--P. vii. Includes bibliographical references (p. 118-121).
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20

Cavan, David Anthony. "An investigation of the HLA associations with type 1 diabetes mellitus and Graves' disease." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404013.

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21

Costa, Patricia Grativol. "Estudo comparativo do tratamento da retração da pálpebra superior com toxina botulínica tipo A em pacientes nas fases aguda e crônica da orbitopatia distireoidiana ao longo de 6 meses de seguimento." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5149/tde-14102008-160447/.

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INTRODUÇÃO: O objetivo do presente estudo é apresentar dados morfométricos da fenda palpebral e da função do músculo levantador da pálpebra superior, ao longo de 6 meses de seguimento, após a aplicação da toxina botulínica tipo A, em pacientes com retração palpebral nas fases aguda e crônica da orbitopatia distireoidiana. MÉTODOS: Estudo prospectivo, no qual foram incluídos 24 indivíduos, divididos em dois grupos, agudos (n=12) e crônicos (n=12). Foram submetidos à aplicação de toxina botulínica na dose de 5 UI/0,1 ml em uma das pálpebras superiores e seguidos por 6 meses. A avaliação palpebra
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22

Rao, Prakash Venugopal. "Studies on thyrotropin receptor antibodies from experimental animal models of Graves' disease and in human patients." Thesis, King's College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404707.

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23

Majima, Takafumi. "Research for pathological state of secondary osteoporosis in type 2 diabetes mellitus and in Graves' disease." Kyoto University, 2008. http://hdl.handle.net/2433/135922.

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Vareman, Klara. "Radiojodbehandling vid Graves sjukdom: långvarig effekt och påverkan på livskvalitet." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-101761.

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Bakgrund: Graves sjukdom är den vanligaste formen av hypertyreos med en incidens på 20 fall per 100 000 individer och år. Graves sjukdom är ett autoimmunt tillstånd där autoantikroppar riktade mot tyreoideastimulerande hormonreceptorer (TSH-R) orsakar okontrollerad syntes och sekretion av tyreoideahormonerna trijodtyronin (T3) och tyroxin (T4). Hur tillståndet uppkommer är inte fullständigt förstått, riskfaktorer inkluderar dock rökning, kvinnligt kön och emotionell stress. Det finns i dagsläget tre etablerade behandlingsmetoder vid Graves sjukdom, dessa är tyreostatikabehandling, radiojodbeha
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25

Horn, Je'nine. "The analysis of 6- and 24-hour iodine-131 thyroid uptake in patients with Graves' disease at Universitas Hospital." Thesis, [Bloemfontein?] : Central University of Technology, Free State, 2007. http://hdl.handle.net/11462/102.

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Thesis (M.Tech.)(Nuclear Medicine) -- Central University of Technology, free State, 2007<br>In the South African Health Services (SAHS) it is each health worker’s responsibility to find ways to reduce health care cost and improve health service to the public. The measurement of radioactive iodine uptake (RAIU) by the thyroid gland for diagnostic purposes has been used as early as the 1940s. The 24-hour (hr) iodine-131 (131I) uptake measurement is traditionally used for the calculation of the 131I administered activity for therapy dosage. This entails that the patient’s hospitalisation is prol
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26

Garbim, Janaina Luisa Leite. "Estudo dos herpesvirus humanos tipo 6 e tipo 1 e sua inter-relação com o gene TP53 em diferentes condições patologicas." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310281.

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Orientador: Laura Sterian Ward<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-09T04:46:06Z (GMT). No. of bitstreams: 1 Garbim_JanainaLuisaLeite_D.pdf: 8361906 bytes, checksum: b8f6cf0d2690bfc52710d97eef61e003 (MD5) Previous issue date: 2007<br>Resumo: Interações entre vírus, o sistema imunológico e a ação de enzimas detoxificantes têm sido associadas à etiologia de muitas doenças incluindo o câncer e várias doenças auto-imunes. Investigamos o papel dos herpes vírus tipo 6 (HHV-6) e tipo 1 (HHV-1) e das variantes d
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27

Marín, Sánchez Ana María. "Mecanismos de tolerancia al receptor de la tirotropina (TSHR): Análisis de su contribución a la respuesta autoinmune en la enfermedad de Graves." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670647.

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La generació de l’amplíssim repertori de receptors dels limfòcits T al timus comporta inevitablement la sortida a perifèria de limfòcits autoreactius que, quan els mecanismes de tolerància perifèrica fracassen, poden generar respostes autoimmunitàries que donin lloc a malalties autoimmunitàries. Es coneixen exemples de malalties autoimmunes (p.ex. APECED OMIM # 240300) i de models animals que demostren que els defectes de tolerància central i, concretament, dels punts de control de el desenvolupament dels limfòcits T al timus, donen lloc a malalties autoimmunitàries òrgan-específiques. Els mec
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Quintino-Moro, Alessandra 1973. "Infertilidade em mulheres com Doença de Graves e Tireoidite de Hashimoto : Infertility among women with Graves's disease or Hashimoto's thyroiditis." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308429.

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Orientadores: Arlete Maria dos Santos Fernandes, Denise Engelbrecht Zantut Wittmann<br>Dissertação (Mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2019-01-09T11:51:06Z (GMT). No. of bitstreams: 1 Moro_AlessandraQuintino_M.pdf: 1160579 bytes, checksum: da4d51faeb6041f68c9c786482aef230 (MD5) Previous issue date: 2013<br>Resumo: A disfunção autoimune, representada pelo hipertireoidismo da Doença de Graves (DG) e pelo hipotireoidismo da Tireoidite de Hashimoto (TH), ocorre de forma mais frequente em mulheres e interfere no mecanismo da
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29

Serra, Lídia Maria Ramos. "Os efeitos do programa musical nos estádios moderados e graves de demência." Master's thesis, Universidade de Évora, 2010. http://hdl.handle.net/10174/19015.

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O objetivo deste estudo foi verificar qual o efeito de um programa musical de 12 semanas, na sintomatologia neuropsiquiátrica e depressiva, e nas expressões emocionais em doentes com Doença de Alzheimer (DA). Participaram 13 sujeitos com diagnóstico de DA em fase moderada-grave da doença: 8 dos participantes integraram o programa musical e, os restantes 5, o grupo de controlo. Para identificar os estádios de demência foi utilizada a Escala de Deterioração Global e para a avaliação dos sintomas foram aplicadas, antes e depois do tratamento, o Inventário Neuropsiquiátrico, a Escala de Cornell pa
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Ranzani, Priscila Moreci [UNESP]. "O processo de comunicação médico/família/criança: a percepção de mães de crianças portadoras de doenças crônicas graves." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/98436.

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Made available in DSpace on 2014-06-11T19:29:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-08-28Bitstream added on 2014-06-13T19:59:18Z : No. of bitstreams: 1 ranzani_pm_me_botfm.pdf: 382771 bytes, checksum: 59f993e46d90b06ff512a86888818895 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A comunicação de más notícias a familiares de crianças com doenças crônicas graves, é uma função difícil na prática médica, que tem influência direta no comportamento e bem-estar da criança e da família, determina a satisfação com os cuidados recebidos, o entendime
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Johansson, Sofia. "Familjegrav eller praktisk lösning? : en studie kring järnålderns dubbelgravar." Thesis, Södertörns högskola, Arkeologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-31908.

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The aim of this essay is to discuss the double graves existence, content and meaning during the Swedish Iron Age. Being buried in pairs seems to have been relatively rare. Is the double grave a family grave or was one of the individuals a human sacrifice? The focus of this essay will be to discuss the possible relationship the people in the double graves may have had, but also to see how rare the grave type is with the help and inspiration of theories by Sarah M. Nelson. Are the graves family style graves such as husband and wife or parent and child? Are there any other possibilities for the e
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Ranzani, Priscila Moreci. "O processo de comunicação médico/família/criança: a percepção de mães de crianças portadoras de doenças crônicas graves /." Botucatu : [s.n.], 2009. http://hdl.handle.net/11449/98436.

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Orientador: Gimol Benzaquen Perosa<br>Banca: Sáskia Maria Wiegerinck Fekete<br>Banca: Regina Helena de Lima Caldana<br>Resumo: A comunicação de más notícias a familiares de crianças com doenças crônicas graves, é uma função difícil na prática médica, que tem influência direta no comportamento e bem-estar da criança e da família, determina a satisfação com os cuidados recebidos, o entendimento das informações médicas, a adesão a tratamentos, muitas vezes invasivos e dolorosos, e, em última instância, repercute no estado de saúde do paciente. Esta pesquisa teve por objetivo analisar a percepção
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33

Engelmann, Constanze. "Die Beiträge von Paul Julius Möbius (1853-1907) zu den Konzeptgeschichten der Migräne, Neuroophthalmologie und des Morbus Basedow." Doctoral thesis, Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-209838.

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Der erste Schwerpunkt der vorliegenden Arbeit resümiert den neurologischen Forschungsstand Ende des 19. Jahrhunderts zum Thema Migräne. Vergleichend dazu wird das Wirken des Leipziger Neurologen, Psychiaters und Wissenschaftspublizisten Paul Julius Möbius (1853-1907) zu diesem Krankheitsbild betrachtet. Folglich wird in der ersten Publikation seine 1894 erschienene Monographie „Die Migräne“ mit zeitgenössischen, heute teils als medizinhistorische Standardwerke geltenden, Werken europäischer Kollegen korreliert. Als Ergebnis wird formuliert, dass sich die Ansichten von Möbius und seiner Kollege
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Santos, Thiago Adler Ralho Rodrigues dos. "US-Doppler colorido da glândula tireoide, em pacientes com doença de Graves, antes e após radioiodoterapia (131I): correlação com quadro clínico-laboratorial." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5151/tde-07082017-091322/.

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INTRODUÇÃO: A doença de Graves (DG), juntamente com a tireoidite de Hashimoto, compõe as doenças endócrinas autoimunes mais comuns, atingindo cerca de 5% da população. Entre as opções terapêuticas para o tratamento do hipertireoidismo induzido pela DG, encontram-se as drogas antitireoidianas, o iodo radioativo (131I) e a cirurgia. A ultrassonografia Doppler (US-Doppler) como parâmetro de resposta ao tratamento da DG pode ser muito útil e foi pouco pesquisada no acompanhamento do tratamento por radioiodo. OBJETIVO: O objetivo do presente estudo foi avaliar a eficácia da US-Doppler no acompanham
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Bedin, Márcia Regina. "Associação dos polimorfismos -318C/T, CT60 e A49G do gene CTLA4, R620W do gene PTPN22 e A946T do gene IFIH1 em pacientes pediátricos com doença autoimune tireoidiana e diabetes mellitus tipo 1." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-27092013-123929/.

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As doenças autoimunes da tireoide (DAIT) representadas, principalmente pela doença de Graves (DG) e tireoidite de Hashimoto (TH), apresentam causas multifatoriais, incluindo fatores genéticos e ambientais. Diversos genes estão envolvidos, entre eles CTLA4, PTPN22 e mais recentemente IFIH1, principalmente quando associados a diabetes mellitus tipo 1 (DM1). OBJETIVOS: Determinar a frequência alélica e genotípica dos polimorfismos: -318C/T, A49G e CT60 do CTLA4, R620W do PTPN22 e A946T do IFIH1 em pacientes pediátricos portadores de DG, TH e DM1 associado a TH e em uma população controle normal,
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Plöhn, Svenja [Verfasser], and Utta [Akademischer Betreuer] Berchner-Pfannschmidt. "The crucial role of sphingosine-1-phosphate and the therapeutic potential of fingolimod for Graves´ disease and associated orbitopathy / Svenja Plöhn ; Betreuer: Utta Berchner-Pfannschmidt." Duisburg, 2019. http://d-nb.info/1191692949/34.

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Hata, Misako. "Comparison of a novel cell-based reporter assay and a competitive binding ELISA for the detection of thyrotropin-receptor (TSHR) autoantibodies (TRAb) in Graves' disease patients." Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1262099140.

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Allen, Abigail E. "The Effects of a Set of Novel Compounds on Interferon-gamma Induced Major Histocompatibility Complex (MHC) Class II Molecules in Cultured Thyroid Cells." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1534199427178941.

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Ratto, Lilian Ribeiro Caldas. "Prevalência da Comorbidade entre Transtornos Mentais Graves e Transtornos Devido ao Uso de Substâncias Psicoativas em São Paulo, Brasil." Universidade de São Paulo, 2001. http://www.teses.usp.br/teses/disponiveis/5/5137/tde-02072004-163541/.

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OBJETIVOS: O presente estudo visou estimar a prevalência da comorbidade entre transtornos mentais graves e o abuso de substâncias psicoativas, e estudar os fatores associados a essa comorbidade, em pacientes com transtornos mentais graves residentes em São Paulo. MÉTODO: O estudo teve desenho de corte transversal. Vinte serviços de saúde mental (emergências, hospitais psiquiátricos e ambulatórios) foram pesquisados, a fim de identificar todos os pacientes com idade entre 18 e 65 anos, com diagnóstico clínico de transtorno mental grave, que fossem residentes em um dos 7 distritos administrativ
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40

Constable, Fiona Elizabeth. "Biology and epidemiology of Australian grapevine phytoplasmas." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phc756.pdf.

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41

Gutschow, Minique. "Resistance to Botrytis cinerea in parts of leaves and bunches of grapevine." Thesis, Stellenbosch : Stellenbosch University, 2001. http://hdl.handle.net/10019.1/52435.

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Thesis (MScAgric)--University of Stellenbosch, 2001.<br>ENGLISH ABSTRACT: Knowledge of the presence of Botrytis cinerea in morphological parts of bunches and leaves of grapevine would help to find a reliable, sensitive, and specific assay to verify the actual occurrence of latent infection, and to plan strategies for the effective control of B. cinerea bunch rot. The aim of this study was (i) to determine natural B. cinerea infection at specific sites in leaves and bunches of grapevine at different phenological stages, and (ii) to determine resistance in the morphological parts to diseas
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42

Freeborough, Michael-John 1971. "A pathogen-derived resistance strategy for the broad-spectrum control of grapevine leafroll-associated virus infection." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53285.

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Thesis (PhD)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: Grapevine leafroll-associated virus-3 is one of ten members of the C/osteroviridae that are known to infect grapevine. Nine of these viruses are associated with grapevine leafroll disease, of which GLRaV-1 and GLRaV-3 are the most important and widespread. Members of the C/osteroviridae are unique amongst the viruses, as it is the only known family whose members encode a heat shock protein 70 kOa homolog (Hsp70h). The Hsp70h is a movement protein (MP) that is required for the active translocation of the virion structur
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43

White, Chana-Lee. "The characterization of the basidiomycetes and other fungi associated with esca of grapevines in South Africa." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5319.

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Thesis (MSc (Plant Pathology))--University of Stellenbosch, 2010.<br>ENGLISH ABSTRACT: Esca is a disease affecting grapevines and is potentially devastating as there are economic losses due to a decrease in yield, wine quality and berry quality. Vineyards also need to be replaced earlier and therefore esca has a great impact on the wine, table grape and raisin industries. The disease is known to affect vineyards worldwide and has been studied extensively in Europe, but not in South Africa. Esca diseased grapevines were observed for the first time prior to 1981 in South African vineyards.
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Fazeli, Claudia Fariba. "Molecular detection of grapevine leafroll associated closteroviruses (GLRaVs) and the genome organisation of GLRaV-1." 1998, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phf2868.pdf.

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45

Richards, Ian. "Autologous mixed lymphocyte reaction in myasthenia gravis." Thesis, University of Bath, 1987. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379569.

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Van, Straten Celene Debra. "The construction of plant expression vectors for the introduction of leafroll disease resistance in grapevine." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51950.

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Thesis (MSc)--University of Stellenbosch, 2000.<br>ENGLISH ABSTRACT: Grapevine leafroll is one of the most damaging viral diseases that affect many viticultural regions of the world. Numerous reports over the last few years have associated closterovirus-like particles with leafroll disease. To date, eight serologically distinct closteroviruses have been isolated from leafroll infected vines, of which grapevine leafroll associated closterovirus-3 (GLRaV-3) is the best characterized. Virus resistance in transgenic plants based on the expression of a virusderived gene is known as pathogen
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Van, Eeden C. (Christiaan). "The construction of gene silencing transformation vectors for the introduction of multiple-virus resistance in grapevines." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/53764.

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Thesis (MSc)--University of Stellenbosch, 2004.<br>ENGLISH ABSTRACT: Viruses are some of the most important pathogens of grapevines. There are no effective chemical treatments, and no grapevine- or other natural resistance genes have been discovered against grapevine infecting viruses. The primary method of grapevine virus control is prevention by biological indexing and molecular- and serological screening of rootstocks and scions before propagation. Due to the spread of grapevine viruses through insect vectors, and in the case of GRSPaV the absence of serological screening, these metho
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Lardner, Richard. "Early diagnosis and detection of Eutypa dieback of grapevines." Title page, table of contents and abstract only, 2003. http://hdl.handle.net/2440/37969.

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Eutypa dieback of grapevines, caused by Eutypa lata, is a major cause of reduced longevity in vineyards worldwide. The fungus grows in the woody tissue of infected vines, producing translocatable toxins that cause foliar symptoms of the disease. By the time foliar symptoms are evident the pathogen may have become well established in the vine. One aim of this study was to develop DNA markers to allow rapid reliable identification of E. lata and to detect the pathogen in infected wood. The second aim was to analyse secondary metabolite production by E. lata in order to gain information on the co
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Ren, Siqian, and 任思倩. "The effects of polyphenols from grapes to prevent cardiovascular disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193801.

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Background: Cardiovascular disease is the leading cause of mortality and morbidity in the world and has something to do with daily diet. The polyphenol is the most abundant compound in daily diet, including grape. The red wine was rich in polyphenol because of composing much grape. Early study has already confirmed the “French Paradox” in cardiovascular protection power, which shed light on the dietary modulation on disease. Objective: The main objective of the study was to evaluate the effect of products containing polyphenol such as red wine extract, grape juice and grape extract tablets or
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Hinz, Johan. "Length of antithyroid regimens and relapsing rates of Grave’s Disease." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-78020.

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Background Grave’s Disease (GD) is an autoimmune disease where autoantibodies through receptor signalling stimulate the thyroid gland peroxidase to produce thyroxine (T4) and triiodothyronine (T3). Antithyroid drugs (ATD) act by inhibiting peroxidase to catalyse the production of T4 and T3. ATD have severe side-effects: agranulocytosis and liver damage. Withdrawal of ATD therapy is affiliated with a 50% risk of relapsing GD. There is no consensus considering the optimal length of ATD therapy to minimise the relapse risk. Aim To investigate if there is a difference in relapse rate between patie
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