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Leime, Aine Ni. "Masculinities and Aging in Ireland." Innovation in Aging 4, Supplement_1 (2020): 826. http://dx.doi.org/10.1093/geroni/igaa057.3017.

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Abstract There is a need for research to gain understanding of the social and cultural constructions of ageing masculinities that, as Gullette emphasises, operate together to construct a ‘culture of decline’. This presentation explores how cultural images of older men inform constructions of ageing and lived realities in Ireland. It draws on the Irish findings from a cross-national, inter-disciplinary project conducted in 2019 investigating older men’s perceptions of how they are represented in film and advertising. It applies innovative narrative and thematic analysis to data from four focus
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Ingelmann, Anja, and Boris Dunkel. "Neuer Hero-Chef nimmt Snacks stärker in den Blick." Lebensmittel Zeitung 77, no. 17 (2025): 12. https://doi.org/10.51202/0947-7527-2025-17-012.

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Goss, Marcin, Iwona Wawer, and Katarzyna Paradowska. "Radioprotekcyjne właściwości ekstraktów z kory sosny." HERBALISM 8, no. 1 (2023): 73–94. http://dx.doi.org/10.12775/herb.2022.005.

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Zbadano przeżywalność komórek nerek zielonej małpy (GMK) poddanych rosnącym dawkom promieniowania γ. Do hodowli komórek dodano kompleks 99mTcDMSA (technetu 99mTc z kwasem merkaptobursztynowym, DMSA). Rozmiary zmian post-radiacyjnych oszacowano na podstawie liczenia komórek. Dodanie ekstraktów z kory zwiększyło przeżywalność komórek, w porównaniu do grupy bez dodatku radioizotopu, a zwłaszcza potraktowanej technetem bez środków ochronnych. Badania ekstraktów z sosny zwyczajnej Pinus silvestris i Pinus maritina (Pyc-nogenol) metodą EPR pokazały, że oba są efektywne w zmiataniu rodnika DPPH. Suge
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Zarzecka, Krystyna, Agnieszka Ginter, and Iwona Mystkowska. "Wartość odżywcza i prozdrowotna zbóż bezglutenowych." HERBALISM 10, no. 1 (2024): 138–48. http://dx.doi.org/10.12775/herb.2024.012.

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W pracy przedstawiono charakterystykę wybranych gatunków zbóż niezawierających białek glutenowych z podaniem zawartości składników odżywczych i związków bioaktywnych oraz produktów zbożowych stosowanych przez konsumenta. Omówiono białka glutenowe i znaczenie diety bezglutenowej. Podkreślono, że bezglutenowe produkty zbożowe zawierają mniej składników mineralnych, witamin z grupy B i błonnika i z tego powodu dieta bezglutenowa powinna być wzbogacana nie tylko o pseudozboża, ale też o inne produkty naturalnie bezglutenowe, takie jak: warzywa i owoce, oleje roślinne, nasiona roślin strączkowych,
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Fröhlich, Sebastian. "Johannes Treutler (1820–1892) – kontekst historyczno- -kulturowy oraz postać pustelnika z Mariańskiej Góry." HERBALISM 9, no. 1 (2023): 178–82. http://dx.doi.org/10.12775/herb.2023.014.

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Ważnym elementem w życiu Johannesa Treutlera jest pustelnia – to tam zaczyna interesować się recepturami i wytwarzaniem preparatów zielarskich; prawdopodobnie dzięki strojowi pustelniczemu (a konkretnie – habitowi franciszkańskiemu)otrzymuje przepis na balsam jerozolimski. Jednak Treutler życie pustelnicze prowadzi w czasach, gdy nie ma ogólnych norm dotyczących jego stanu – choć pierwsi anachoreci pojawiają się około III w. [1], to prawna regulacja tej grupy na poziomie całego Kościoła pojawia się dopiero w Kodeksie prawa kanonicznego z 1983 r. Tak więc do drugiej połowy XX w. pustelnicy i pu
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Zych, Maria, Weronika Wojnar, Anna Bońka, and Ilona Kaczmarczyk-Sedlak. "Wpływ chryzyny na parametry histomorfometryczne kości owariektomizowanych szczurów." HERBALISM 3, no. 1 (2021): 41–54. http://dx.doi.org/10.12775/herb.2017.003.

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Osteoporoza jest schorzeniem wynikającym między innymi z niedoboru estrogenów u kobiet w okresie menopauzalnym. Choroba ta charakteryzuje się zmniejszoną wytrzymałością kości na uszkodzenia mechaniczne. Osłabienie układu szkieletowego wynika z zaburzeń na poziomie mikroarchitektury tkanki kostnej. Aby zapobiec rozwojowi osteoporozy pomenopauzalnej, można stosować terapię hormonalną, która jednak niesie za sobą wiele działań niepożądanych. W związku z tym poszukuje się bezpiecznej alternatywy dla hormonalnej terapii zastępczej. W tym celu wykorzystywane są związki pochodzenia roślinnego, w tym
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Baranowska, Alicja, Iwona Mystkowska, Krystyna Zarzecka, and Marek Gugała. "Cenne owoce maliny właściwej (Fructus Rubi idaei)." HERBALISM 3, no. 1 (2021): 70–79. http://dx.doi.org/10.12775/herb.2017.005.

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Malina właściwa (Rubus idaeus L.) jest jedną z najstarszych roślin znanych ludzkości i od wieków wykorzystywana do celów spożywczych oraz leczniczych. O przydatności owoców maliny (Fructus Rubi idaei) i liści (Folium Rubi idaei) decyduje w dużej mierze ich skład chemiczny. Wartość biologiczna owoców maliny właściwej zależy od poziomu antyoksydantów, do których między innymi zalicza się kwas askorbinowy i antocyjany. Natomiast o smaku i aromacie owoców decyduje stopień ich dojrzałości, odmiana, zawartość cukrów prostych, kwasów organicznych oraz substancji lotnych. Owoce maliny są również bogat
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Henning, Peter. "T-DM1 als Innovation beim HER2-positiven Brustkrebs: Antikörper und Zytostatikum als duale Wirkkombination." Onkologische Welt 03, no. 04 (2012): 172. http://dx.doi.org/10.1055/s-0038-1630203.

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Das Antikörper-Wirkstoff-Konjugat Trastuzumab-Emtansin (T-DM1) steht für ein neues Wirkprinzip in der Therapie des HER2-positiven Mammakarzinoms. über Thioether Linker SMCC ist das Zytostatikum DM1, ein Spindelgift aus der Gruppe der Maytansinoide an den Antikörper Trastuzumab gebunden.
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Dykiel, Magdalena, Angelika Uram-Dudek, and Iwona Wajs. "Wpływ marynowania mięsa wieprzowego z wykorzystaniem fermentowanych niepasteryzowanych octów na jego właściwości reologiczne." HERBALISM 10, no. 1 (2024): 40–53. http://dx.doi.org/10.12775/herb.2024.004.

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Konsumenci domagają się mięsa i produktów mięsnych z naturalnymi składnikami, które gwarantują wysoką jakość żywności, a im samym zapewnią zdrowie. Celem podjętych badań było określenie wpływu marynaty z wykorzystaniem niepasteryzowanych octów i octu spirytusowego na właściwości reologiczne mięsa wieprzowego. Surowcem do badań było mięso wieprzowe – karkówka. Karkówkę podzielono na pięć porcji, z czego jedna stanowiła próbę kontrolną (bez octu), a pozostałe cztery marynowano octem: I – spirytusowym (pH 2,83), niepasteryzowanym octem: II – jabłkowym (pH 3,24), III – gruszkowym (pH 3,72), IV – m
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Stolarek, Karolina, Angelika Uram-Dudek, Iwona Wawer, and Katarzyna Paradowska. "Ocena jakości szafranu (Crocus sativus L.) z wykorzystaniem metod spektroskopowych." HERBALISM 8, no. 1 (2023): 6–26. http://dx.doi.org/10.12775/herb.2022.001.

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Szafran (Croccus sativus L.) to wyjątkowa roślina, ceniona na całym świecie. Uznawana za jedną z najdroższych i najszlachetniejszych przypraw. Właściwości szafranu znali już starożytni, którzy nie tylko dodawali szafran do dań i napitków, barwili nim tkaniny, ale także stosowali go w celach prozdrowotnych. Roślina ta jest doskonałym środ-kiem wspomagającym trawienie, poprawiającym nastrój i apetyt. W wielu badaniach naukowych wykazano również jej właściwości antydepresyjne, przeciwdrgawkowe, przeciwnowotworowe, antybakteryjne oraz antyoksydacyjne. Ze względu na szerokie zastosowanie tego mater
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Moritoki, Yoshinobu, Kentaro Mizuno, Taiki Kato, Takahiro Yasui, and Yutaro Hayashi. "Unusual Cause of Acute Scrotal Pain-Inflammatory Noncommunicating Hydrocele: A Pediatric Case Report." Case Reports in Medicine 2018 (2018): 1–4. http://dx.doi.org/10.1155/2018/2862514.

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The etiology of scrotal pain is clinically classified in terms of the necessity for emergency surgery. Lately, color Doppler ultrasonography has reduced unnecessary surgeries, but there are still some cases that require immediate exploration because of an uncertain diagnosis. Here, we describe the case of a 14-month-old boy, who could not deliver his complaint accurately, presenting with a grumpy mood and a red swollen scrotum. Emergency surgery revealed that the cause was intense inflammation of the hydrocele wall, which typically does not cause acute scrotum. We also reviewed rare etiologies
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Luca Salvaggio. "Metaponto, strigili compositi in bronzo e ferro. Tecniche di fabbricazione e inquadramento cronologico." Quaderni di ACMA, no. 2 (September 25, 2024): 329–41. http://dx.doi.org/10.69590/h2nfey53.

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La ricerca archeologica in Lucania ha portato alla luce quattro strigili realizzati con una tecnica mista che unisce il bronzo e il ferro. In questa sede, si propone una rilettura dei dati alla luce dello studio di altri quattro strigili provenienti dalla necropoli metapontina di proprietà Giacovelli, finora inediti. L’analisi delle tecniche di fabbricazione ha rivelato l’esistenza di due gruppi distinti. Il primo gruppo è caratterizzato dal riutilizzo di strigili rotti o difettosi, ritagliati e assemblati tra loro con l’uso di rivetti o a incastro. Il secondo gruppo, attestato in forma ridott
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Monika Kotowska. "Charakterystyka członka zorganizowanej grupy przestępczej z punktu widzenia kryminologii humanistycznej." Archives of Criminology, no. XXXV (January 1, 2013): 283–303. http://dx.doi.org/10.7420/ak2013j.

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The key thesis in humanistic criminology is based on the premise that criminal behaviour in individuals is always an effect of their sovereign decisions, even if – as this is the case in every the type of human behaviour – it is influenced by a variety of factors. The main problem is the origin of a crime, understood as an individual process leading to a crime, or in cases where minors are involved as perpetrators – to a punishable act. The origin of crime would then be concerned with a varied and mostly complex phenomena of the human psyche. The core notion here being the volitional process,
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Moran, Albert. "The International Face of Australian Television." Media International Australia 121, no. 1 (2006): 174–87. http://dx.doi.org/10.1177/1329878x0612100119.

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Australian television has always been part of an international cultural system. Programming, personnel, material resources, ideas and knowledge are among the elements that, historically, have moved between an audiovisual space, both here and elsewhere. Media executive Reg Grundy has been an important figure in this system. Over nearly 40 years, he built a television empire of considerable international significance. After sketching out this career, the article proceeds to outlines three moments in his company's development. The first occurred in the 1960s and early 1970s when it imported and r
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15

Walter, Vincent P., Florin-Andrei Taran, Markus Wallwiener, et al. "Verteilung des 21-Gen-Rezidiv-Scores bei Patientinnen mit primärem Mammakarzinom in Deutschland." Senologie - Zeitschrift für Mammadiagnostik und -therapie 18, no. 03 (2021): 285–93. http://dx.doi.org/10.1055/a-1578-9549.

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Zusammenfassung Einleitung Multigen-Assays werden zunehmend als Entscheidungshilfe für eine Chemotherapie beim Mammakarzinom verwendet. Wir stellen hier den 21-Gen-Recurrence-Score (RS) von Patientinnen mit Brustkrebs vor, die routinemäßig in Deutschland untersucht wurden. Patientinnen und Methoden 4695 Patientinnen mit hormonrezeptorpositivem und HER2-negativem Brustkrebs im Frühstadium (pT1–3, pN0–1, M0) wurden einer retrospektiven Analyse unterzogen. Bei diesen Patientinnen wurde in Deutschland zwischen November 2015 und Juli 2018 der Genexpressionstest Oncotype DX zur Ermittlung des Recurr
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Grasseni, Cristina. "Seeds of Trust. Italy's Gruppi di Acquisto Solidale (Solidarity Purchase Groups)." Journal of Political Ecology 21, no. 1 (2014): 178. http://dx.doi.org/10.2458/v21i1.21131.

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This article presents a case study of the solidarity economy in Italy: the Italian G.A.S. – Gruppi di Acquisto Solidale, which I translate as Solidarity Purchase Groups. GAS are often conceptualized as "alternative food networks". Beyond this categorization, I highlight their novelty in relational, political, and ecological terms, with respect to their capacity to forge new partnerships between consumers and producers. Introducing an ethnographic study that I have developed in a recent monograph (Grasseni 2013), I dwell here in particular on how the solidarity economy is embedded in practice.
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Isaacs, I. M. "The π-character theory of solvable groups". Journal of the Australian Mathematical Society. Series A. Pure Mathematics and Statistics 57, № 1 (1994): 81–102. http://dx.doi.org/10.1017/s1446788700036077.

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AbstractThere is a deeper structure to the ordinary character theory of finite solvable groups than might at first be apparent. Mauch of this structure, which has no analog for general finite gruops, becomes visible onyl when the character of solvable groups are viewes from the persepective of a particular set π of prime numbers. This purely expository paper discusses the foundations of this πtheory and a few of its applications. Included are the definitions and essential properties of Gajendragadkar's π-special characters and their connections with the irreducible πpartial characters and thei
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Fehm, Tanja N., Manfred Welslau, Volkmar Müller, et al. "Update Mammakarzinom 2022 Teil 3 – Brustkrebs in frühen Krankheitsstadien." Senologie - Zeitschrift für Mammadiagnostik und -therapie 19, no. 04 (2022): 365–75. http://dx.doi.org/10.1055/a-1962-3985.

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ZusammenfassungIn dieser Übersichtsarbeit werden neueste Entwicklungen in der Prävention von Brustkrebs und Behandlung von Patientinnen mit frühen Krankheitsstadien mit Mammakarzinom zusammengefasst. Die Ermittlung von individuellen Erkrankungsrisiken nach molekularen Subtypen wurde in einer großen epidemiologischen Studie untersucht. Im Bereich der Behandlung gibt es neue Daten zur Langzeitnachbeobachtung der Aphinity-Studie ebenso wie neue Daten zur neoadjuvanten Therapie von HER2-positiven Patientinnen mit Atezolizumab. Biomarker wie Residual Cancer Burden wurden im Zusammenhang mit einer P
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Molinelli, Chiara, Virginia Delucchi, Eva Blondeaux, et al. "Dose-dense adjuvant chemotherapy in patients with HER2-low early breast cancer: An exploratory analysis of the GIM2 trial." Journal of Clinical Oncology 42, no. 16_suppl (2024): 532. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.532.

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532 Background: Dose-dense (DD) adjuvant chemotherapy represents the standard treatment for patients with node-positive early-stage HER2-negative breast cancer, but its role in HER2-low disease is unknown. In this exploratory analysis of the Gruppo Italiano Mammella 2 (GIM2) trial, we investigated efficacy of DD chemotherapy among patients affected by HER2-negative breast cancer according to HER2 immunohistochemistry (IHC) score (low vs. zero). Methods: Patients with node-positive early breast cancer were randomly assigned to receive either DD or standard schedule anthracycline- and taxane-bas
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Cinieri, S., L. Orlando, V. Lorusso, et al. "New biweekly combination of trastuzumab, docetaxel, and gemcitabine for HER2-positive metastatic breast cancer: First early results from a phase II multicentric trial on behalf of Gruppo Oncologico Italia Meridionale." Journal of Clinical Oncology 27, no. 15_suppl (2009): 1096. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.1096.

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1096 Background: The clinical activity of the combination of chemotherapy plus trastuzumab in HER-2 overexpressing metastatic breast cancer has been well documentated. We report the first results in terms of efficacy and safety of a phase II trial on biweekly combination of trastuzumab plus docetaxel and gemcitabine as first line therapy in HER-2-positive metastatic breast cancer patients. Methods: Patients at first relapse or with synchronous metastasis, were treated with trastuzumab (4 mg/kg, loading dose 6 mg/kg) plus gemcitabine (1000 mg/m2) plus docetaxel (50 mg/m2) as biweekly schedule.
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Jentzmik, Florian. "Standard Changing News in der Urologischen Onkologie 2020." Der Klinikarzt 49, no. 11 (2020): 462–66. http://dx.doi.org/10.1055/a-1296-7235.

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ZUSAMMENFASSUNGMit Einführung der Checkpoint-Inhibitoren hat sich die Therapielandschaft des metastasierten Urothelkarzinoms grundlegend verändert und verbessert. Ein völlig neuer Ansatz ist der Einsatz von Avelumab als Erhaltungstherapie bei Patienten mit lokal fortgeschrittenem oder metastasiertem Urothelkarzinom, die zumindest einen stabilen Krankheitsverlauf nach platinhaltiger Induktionstherapie hatten. In der JAVELIN bladder 100-Studie ereichte Avelumab + best supportive care (BSC) im Vergleich zur alleinigen BSC-Gruppe ein signifikant längeres Gesamtüberleben in den beiden primären Popu
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Majchrowska, Justyna. "„Dziewczynki mogą wszystko” – o zwalczaniu stereotypu płci na przykładzie strategii marketingowej marki Lego." Media Biznes Kultura, no. 2 (13) (December 21, 2022): 121–32. http://dx.doi.org/10.4467/25442554.mbk.22.019.17105.

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Celem badania była próba zauważenia sposobów prowadzenia strategii marketingowej, w której łamie się stereotypy. Badanie pilotażowe, przeprowadzone za pomocą metody genologicznej analizy tekstu, ze szczególnym nastawieniem na aspekty strukturalny i językowy, pozwoliło zauważyć wielokanałowe komunikowanie nadawcy, Grupy Lego, z odbiorcami – konsumentami z całego świata, w tym z Polski. Poprzez prowadzoną strategię narracyjną firma zwraca uwagę na dotychczasowe, dość krzywdzące, zachowania społeczeństwa w stosunku do wychowywania dziewczynek (i analogicznie chłopców). Ten dualny, zapoczątkowany
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Silva, Rafael Costa da, and Antonio Carlos Sequeira Fernandes. "Review of Oliveirania santa catharinae (sic) Maury 1927 and associated ichnofossils (Itararé Group, Late Carboniferous of Paraná Basin, Brazil)." Terr Plural 15 (2021): e2117741. http://dx.doi.org/10.5212/terraplural.v.15.2117741.029.

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The sedimentary layers of Anitápolis, Santa Catarina, were the subject of relevant discussions about age and paleoenvironment in the first half of the 20th century. Today they are correlated to the ritmites from Itararé Group, but some of the fossils that are part of these studies were not subsequently revised. This is the case of Oliveirania santa catharinae (sic) Maury 1927, a species originally attributed to annelids, and the ichnofossils attributed to it by association. The Annelida fossils were considered here as pseudofossils of inorganic origin. The ichnofossils attributed to Oliveirani
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Jalowiec, Katarzyna Aleksandra, Martin Andres, Behrouz Mansouri Taleghani, Anne Angelillo-Scherrer, Alicia Rovo, and Johanna A. Kremer Hovinga. "Acquired Hemophilia and Plasma Cell Neoplasms, a Rare Association." Blood 134, Supplement_1 (2019): 4930. http://dx.doi.org/10.1182/blood-2019-128048.

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Acquired hemophilia A (AHA) is a rare autoimmune disease caused by circulating autoantibodies inhibiting coagulation factor VIII (FVIII), leading to a clinically significant bleeding diathesis. While in half of AHA cases, no underlying cause is identified, in the other half an association with autoimmune diseases, cancer, the use of certain drugs, pregnancy or the post-partum period is found. We present a case with severe bleeding in which AHA was diagnosed and subsequently a smoldering myeloma was found as underlying disease (case 16, Table 1). We conducted a systematic review of the literatu
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Sulikan, Sulikan. "Pengaruh Peregangan – Pemanasan dan Pemanasan – Peregangan Terhadap Kecepatan Lari 54,86 Meter (60 Yard)." Paradigma: Jurnal Filsafat, Sains, Teknologi, dan Sosial Budaya 24, no. 2 (2018): 1–8. http://dx.doi.org/10.33503/paradigma.v24i2.468.

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 The purpose of the the research is to know the effectiveness of the influence of stretching-up and warming-up-stretching toward the velocity of 60 yard dash. Population used are the students ( male ) of IKIP Budi Utomo Malang S1 program especially the ffth semester. Here the writer takes 80 students as samples from 178 students ramdomly. The samples are divided into 4 gruops by matching them that each group consists of 20 students.The kind of research experiments is using the design of the study latin square. The experiments is done about 4 weeks, once a week. That uses four treatmen as
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Walker, Tania. "THE ROLE OF PROVIDING AN EXPLANATION WITHIN THE CONTEXT OF EMAILED APOLOGIES: A CROSS-CULTURAL APPROACH." Italiano LinguaDue 16, no. 2 (2025): 178–96. https://doi.org/10.54103/2037-3597/27763.

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This article explores differences in the realisation of one apology strategy between Australian learners of Italian, native speakers of Italian and native speakers of Australian English. The strategy in question is providing an explanation, which is here investigated through an analysis of elicited emails addressed to academic staff at university. The analysis demonstrates that while Australian learners of Italian tend to resort to this strategy as an obligatory stage in the performance of apologies, native Italian speakers frequently omit it. Such difference between the two groups is further
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Rossi, Maurizio, Alice Plutino, Andrea Siniscalco, and Alessandro Rizzi. "Teaching color and color science: the experience of an international master course." Electronic Imaging 2020, no. 15 (2020): 165–1. http://dx.doi.org/10.2352/issn.2470-1173.2020.15.color-163.

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There are not many international courses that teach color science applied to non-technical fields. Here, we want to present the experience from a master course organized by Gruppo del Colore – Associazione Italiana Colore and Politecnico of Milano: the Master in Color Design & Technology. It has the aim of training students in the use of color mainly for design purposes, and color science and colorimetry have a big role in the program. The Master is organized in three main phases: Fundamentals, Project Works and Internship. The first part is a series of lectures and frontal lessons that gi
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Sterling, Mark J., David C. Lees, and Dave Grundy. "Xenotorodor stygioxanthus gen. nov., sp. nov. (Lepidoptera, Lecithoceridae, Torodorinae), described from an established population in Spain with discussion of taxonomic placement." Nota Lepidopterologica 46 (March 17, 2023): 103–23. http://dx.doi.org/10.3897/nl.46.101457.

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The family Lecithoceridae is not well represented in the Palaearctic region, with very few taxa in Europe. Here we describe a new genus and species of lecithocerid moth, Xenotorodor stygioxanthus Sterling, Lees & Grundy, gen. nov., sp. nov. The taxon represents a subfamily new to Europe. We consider placement of the genus within Crocanthinae or Torodorinae. We place it in Torodorinae, notwithstanding the reduced gnathos in the male genitalia. DNA barcodes suggest that the taxon belongs within a distal clade of this subfamily. They are over 9.2% pairwise divergent from any hitherto cleanly
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Sterling, Mark J., David C. Lees, and Dave Grundy. "Xenotorodor stygioxanthus gen. nov., sp. nov. (Lepidoptera, Lecithoceridae, Torodorinae), described from an established population in Spain with discussion of taxonomic placement." Nota Lepidopterologica 46, no. () (2023): 103–23. https://doi.org/10.3897/nl.46.101457.

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The family Lecithoceridae is not well represented in the Palaearctic region, with very few taxa in Europe. Here we describe a new genus and species of lecithocerid moth, Xenotorodor stygioxanthus Sterling, Lees & Grundy, gen. nov., sp. nov. The taxon represents a subfamily new to Europe. We consider placement of the genus within Crocanthinae or Torodorinae. We place it in Torodorinae, notwithstanding the reduced gnathos in the male genitalia. DNA barcodes suggest that the taxon belongs within a distal clade of this subfamily. They are over 9.2% pairwise divergent from any hitherto cleanly
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30

Conte, Benedetta, Alessandra Fabi, Francesca Poggio, et al. "T-DM1 EFFICACY AND ACTIVITY IN HER2-POSITIVE METASTATIC BREAST CANCER PATIENTS PROGRESSING AFTER FRONTLINE TAXANE PLUS PERTUZUMAB AND TRASTUZUMAB: AN ITALIAN MULTICENTER OBSERVATIONAL STUDY OF THE GRUPPO ITALIANO MAMMELLA (GIM) STUDY GROUP." Breast 48 (November 2019): S45. http://dx.doi.org/10.1016/s0960-9776(19)30674-5.

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Fabi, Alessandra, Matteo Allegretti, Elena Giordani, et al. "Abstract OT1-22-01: Liquid biopsy and Ado-trastuzumab emtansine (T-DM1): drug-resistance traits in the blood of HER2-positive metastatic breast cancer patients." Cancer Research 83, no. 5_Supplement (2023): OT1–22–01—OT1–22–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-ot1-22-01.

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Abstract Background: A previous study on 22 metastatic breast cancer (mBC) patients (Allegretti et al. Mol Cancer 2021) has associated drug resistance to Ado-trastuzumab emtansine (T-DM1) with two sets of genomic events: a) reversal of HER2 amplification, b) ‘oncogenic replacement’ of HER2 by alternative cancer drivers. To expand on this, we designed GIM21 (Gruppo Italiano Mammella) study. Materials and Methods: GIM21 is a multicentre, prospective study; tumor and circulating total nucleic acids (tTNA and ctTNA) were obtained from primary and metastatic lesions (n=36 altogether), as well as pl
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Möbus, Volker. "Adjuvant Dose-Dense Chemotherapy in Breast Cancer: Standard of Care in High-Risk Patients." Breast Care 11, no. 1 (2016): 8–12. http://dx.doi.org/10.1159/000444004.

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Meta-analyses persistently confirm the superiority of dose-dense chemotherapy in comparison with standard chemotherapy. In contrast, individual studies have shown conflicting results. These may be explained by different risk profiles of the treated patient populations. Some trials show a significant advantage in disease-free survival (DFS) and overall survival (OS) in the estrogen receptor (ER)-negative population only, whereas trials with high-risk populations like GIM-2 (Gruppo Italiano Mammella) and AGO-iddETC (Arbeitsgemeinschaft Gynäkologische Onkologie, intense dose-dense epirubicin, pac
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Reusswig, Fritz. "Landwirtschaft und Klimaskepsis in populistischen Zeiten." GAIA - Ecological Perspectives for Science and Society 33, no. 1 (2023): 132–35. http://dx.doi.org/10.14512/gaia.33.1.3.

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Welche Rolle spielen sozio-demografische und lokale Umweltfaktoren für die Klimawandelwahrnehmung? Der hier besprochene Artikel von Landwehr et al. stellt interdisziplinäre Befunde zu dieser Frage vor, die besonders mit Blick auf die Gruppe der Landwirt(inn)e(n) interessant sind. Die Befunde werfen aber auch Fragen zum Abstraktionsgrad der Klimawahrnehmung, der Rigidität sozialer Identität, der Rolle der Medien und der Zielgruppenstrategie auf. Im Kontext der jüngsten ,,Bauernproteste“ und populistischer Narrative folgert der Autor dieser Reaktion, dass in künftigen interdisziplinären Forschun
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Arecco, L., E. Blondeaux, M. Bruzzone, et al. "243P Prognosis of patients with hormone receptor-positive/HER2-negative early breast cancer according to monarchE and NATALEE trials risk categories: Patient-level analysis of Mammella InterGruppo (MIG) and Gruppo Italiano Mammella (GIM) randomised trials." Annals of Oncology 35 (September 2024): S316. http://dx.doi.org/10.1016/j.annonc.2024.08.186.

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Marchioli, Roberto, Guido Finazzi, Giorgina Specchia, Arianna Masciulli, Maria Rosaria Mennitto, and Tiziano Barbui. "The CYTO-PV: A Large-Scale Trial Testing the Intensity of CYTOreductive Therapy to Prevent Cardiovascular Events in Patients with Polycythemia Vera." Thrombosis 2011 (May 17, 2011): 1–9. http://dx.doi.org/10.1155/2011/794240.

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Polycythemia vera (PV) is a chronic myeloproliferative disorder whose major morbidity and mortality are thrombohaemorragic events. Current guidelines advise maintaining hematocrit (HCT) level below 45% in males and 42% in females. Such targets lean on pathophysiological reasoning, while evidence from ECLAP and PVSG-01, the two largest prospective studies in this disease, suggests no difference in the rate of thrombosis in patients maintained at different HCT values below 50%–52%. Cytoreductive therapy in PV (CYTO-PV) is a multicenter, randomized, and controlled trial assess the benefit/risk pr
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Frolov, Dmitrij. "Reflections on Osip Mandelstam’s Poem “Erected on a Wet Stone …” (1909)." Izvestiia Rossiiskoi akademii nauk. Seriia literatury i iazyka 82, no. 5 (2023): 15. http://dx.doi.org/10.31857/s160578800028323-1.

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The poem “Erected on a wet stone …” was sent in the Autumn of 1909 first to Max Voloshin and them to Vyacheslav Ivanov and is part of “poems in letters” which were only published in the second half of 20th century. The central theme of the poem is the juxtaposition of love and death. Cupid finds himself standing on a tombstone (“green moss and wet stone”) and being surprised by what he discovers tries to avenge on death through love (“illegal flame of the heart”). The poetics of the poem represents another step in the development of Mandelstam’s inherent technique of subtexts and contexts. The
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Morales-Contreras, José Antonio, Jesús Arturo Ruiz-Quiñonez, Alberto Roblero-Hernández, Gibran Horemheb-Rubio, and Samuel Suarez Mendez. "A single BNT162b2 dose protects against SARS-CoV-2: A case report of a family cluster of COVID-19." Revista Biomédica 32, no. 3 (2021): 172–76. http://dx.doi.org/10.32776/revbiomed.v32i3.912.

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Background. Coronavirus 2019 (COVID-19) disease is an infectious disease caused by the virus "Severe Acute Respiratory Syndrome Coronavirus 2" (SARS-CoV-2). This virus generated a pandemic in 2020 and has affected millions of people worldwide. Facing the need to prevent its contagion, the vaccine BNT162b2 was approved in December 2020 in Mexico and started administered in healthcare workers. Case presentation. We presented here, two healthcare workers vaccinated with one single dose of BNT162b2, who lives in a family nucleus with high transmission rate of SARS-CoV-2. These healthcare workers,
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Кутырёва-Чубаля [Kutyriowa-Czubala], Галина [Galina]. "Лексика песенных зачинов в белорусской свадьбе: семантика, структурные трансформации (на примере одной группы текстов)". Acta Baltico-Slavica 40 (28 грудня 2016): 291–309. http://dx.doi.org/10.11649/abs.2016.012.

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Lexical Forms of Song’s Incipits in Belarusian Wedding Cycle: Semantics, Structural Transformations (an Example of One Type of Texts) In the context of the study on dynamic typology and dialectal features of Belarusian folk songs, the paradigm of texts relating to the episode when the Bride parts with her parents is considered here. Such texts have the same lexical and poetic basis; are characterized by common type of incipit in different variants. All of these texts depict an dramatic for the Bride moment of “intrusion” into her backyard “an alien” family – the Groom’s family. Different versi
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Trojanowska, Maria. "Wizerunek herbu miasta Lublina w źródłach archiwalnych z XV–XVIII wieku." Studia Archiwalne 4 (2017): 11–29. http://dx.doi.org/10.4467/17347513sa.17.002.14514.

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W artykule zostały zebrane i opisane źródła ikonograficzne do dziejów herbu miasta Lublina z XV–XVIII w. przechowywane w zasobie Archiwum Państwowego w Lublinie. Wizerunki tego herbu podzielono na trzy grupy w zależności od rodzaju źródła i miejsca występowania znaku. Należą do nich: wyobrażenia na pieczęciach miasta, superekslibrisy na oprawach ksiąg miejskich i zdobienia malarskie o tematyce heraldycznej występujące na kartach tych ksiąg. Najstarsze wizerunki herbu Lublina zachowały się na pieczęciach z początku XV w., które z uwagi na swój urzędowy charakter są też najcenniejszym źródłem he
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Dojwa-Turczyńska, Katarzyna. "Stosunek Polaków do migrantów. Refleksje socjologiczne w świetle wybranych badań empirycznych." Rocznik Europeistyczny 2 (September 27, 2016): 61–82. http://dx.doi.org/10.19195/2450-274x.2.5.

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Kryzys migracyjny roku 2015 można rozpatrywać z różnych perspektyw. Jedną z nich jest płaszczyzna społeczna, która w niniejszym artykule odnosi się do stosunku mieszkańców danego państwa do kwestii uchodźców. Tym społeczeństwem są Polacy. Generalnie stosunek Polaków do innych wedle badań porównawczych w latach 2002–2012 był korzystny. Wśród Europejczyków Polacy sytuowali się na stosunkowo wysokich pozycjach tolerancji dla tych, którzy w Polsce będą szukać schronienia bądź też zdecydują się tu żyć. Badania sondażowe pokazywały także relatywnie bardziej przychylne dla innych postawy Polaków wzgl
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Zalewska, Anna. "FATAL IMMORTALITY. THE BLACKSMITH MOTIF IN POLISH FOLKTALES." Folklore: structure, typology, semiotics 5, no. 1 (2022): 54–68. http://dx.doi.org/10.28995/2658-5294-2022-5-1-54-68.

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Numerous texts of Slavic folklore, including the folk fairy tale, reflect ideas concerning the demonic properties of non-agricultural professions. These include, in particular, the hero of this analysis, namely the blacksmith. The primary research objective involves illustrating the specificity of the fairy tale image of a blacksmith. The peculiarities of his behaviour, forms of interaction with other characters, the attributes of the craft he mastered, the functions he performs, as well as his posthumous status will be taken into account. The fairy tale image of the blacksmith largely corresp
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42

Adirosi, Elisa, Federico Porcù, Mario Montopoli, et al. "Database of the Italian disdrometer network." Earth System Science Data 15, no. 6 (2023): 2417–29. http://dx.doi.org/10.5194/essd-15-2417-2023.

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Abstract. In 2021, a group of seven Italian institutions decided to bring together their know-how, experience, and instruments for measuring the drop size distribution (DSD) of atmospheric precipitation, giving birth to the Italian Group of Disdrometry (in Italian named Gruppo Italiano Disdrometria, GID, https://www.gid-net.it/, last access: 16 May 2023). GID has made freely available a database of 1 min records of DSD collected by the disdrometer network along the Italian peninsula. At the time of writing, the disdrometer network was composed of eight laser disdrometers belonging to six diffe
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43

Luckscheiter, Christian. ",,eine Brücke, ein Band zwischen den Völkern“. : Hermann Wendels Vortrag ,,Der Rhein. Deutschlands oder Europas Strom?“ von 1927 und seine (,jüngst-elsässischen‘) Kontexte." Zeitschrift für Germanistik 33, no. 3 (2023): 524–42. http://dx.doi.org/10.3726/92174_524.

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Abstract Inmitten der nationalistischen ,,Kämpfe um den Rhein“ der 1920er Jahre bezeichnete Hermann Wendel 1927 den Fluss als eine Brücke zwischen den Ländern, durch die das Übernationale an seinen Ufern Wirklichkeit geworden sei. Die ,Formulierungschance‘ Wendels findet sich in einem spezifischen Kontext, der in die Zeit vor 1914 zurückführt: Wendel war Mitglied der 1901 in Straßburg gegründeten Gruppe ,,Das jüngste Elsaß“. Die Diskussionen der Nachkriegsjahre um das deutsch-französische Verhältnis wurden hier bereits zwei Jahrzehnte früher im Zusammenhang mit der sogenannten elsässischen Fra
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Alderton, Zoe. "“Nothing Tastes as Good as Skinny Feels”." International Journal for the Study of New Religions 12, no. 2 (2024): 157–84. http://dx.doi.org/10.1558/ijsnr.27320.

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There has always been something compelling about extreme bodies. Kate Moss exemplifies “the waif,” a body type both frightening and appealing. She is one of the most common celebrities discussed on pro-anorexia (or, pro-ana) websites. To explore the connection between Moss’s body and pro-ana participation, this article examines the potential for an extraordinary body to solidify the aims of an extremist group and to draw in new members. Her unusually slender form affirms this pro-starvation cluster by physically representing the emotional distress that lies at its core. There is no conclusive
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45

Perachino, Marta, Eva Blondeaux, Michelino De Laurentiis, et al. "Impact of young age at diagnosis on survival outcomes in patients with early breast cancer according to tumor subtype: Pooled analysis of 5 randomized clinical trials from the Mammella InterGruppo (MIG) and Gruppo Italiano Mammella (GIM)." Journal of Clinical Oncology 42, no. 16_suppl (2024): 523. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.523.

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523 Background: The incidence of breast cancer (BC) among young patients is increasing. Historically, young age itself has been recognised as a poor prognostic factor for BC. However, there is limited evidence regarding the impact of age at diagnosis and on survival outcomesaccording to tumor subtype. Methods: We collected individual patient (pt)-level data from newly diagnosed stage I to III BC pts participating in 5 randomized clinical trials conducted by Mammella InterGruppo (MIG) and Gruppo Italiano Mammella (GIM) study groups. Patients were categorized into the following age groups based
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46

Blondeaux, Eva, Arlindo R. Ferreira, Francesca Poggio, et al. "Clinical outcomes of patients with breast cancer relapsing after (neo)adjuvant trastuzumab and receiving trastuzumab rechallenge or lapatinib-based therapy: a multicentre retrospective cohort study." ESMO Open 5, no. 4 (2020): e000719. http://dx.doi.org/10.1136/esmoopen-2020-000719.

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BackgroundIn the prepertuzumab era, we evaluated the clinical outcomes of patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer who underwent first-line trastuzumab-based or lapatinib-based therapy according to prior exposure to (neo)adjuvant trastuzumab.Materials and methodsIn this multicentre retrospective cohort study conducted in 14 Italian centres of the Gruppo Italiano Mammella, consecutive patients undergoing first-line trastuzumab or lapatinib-based therapy were included. Analyses were performed according to the type of first-line therapy for m
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Аврамова [Avramova], Цветанка [TSvetanka]. "Словообразувателни модели на жителските имена (nomina habitatorum) в съвременния български и чешки език". Studia z Filologii Polskiej i Słowiańskiej 51 (31 грудня 2016): 45–57. http://dx.doi.org/10.11649/sfps.2016.004.

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Word-formation models of inhabitant nouns (nomina habitatorum) in contemporary Bulgarian and CzechThe article analyses the word-formation models (WFM) of the nomina habitatorum in Bulgarian and Czech. The term WFM is very similar to, but not conterminous with, the concept of word-formation type (WFT) as defined by Miloš Dokulil. WFT is understood here as superordinate in relation to WFM. WFT is defined by the same set of properties as WFM but differs from the latter according to the character of the formant; while in FM the character is physical (formal, based on sound), in WFT the character o
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Ferroni, Roberta. "AFFECTIVE AND INCLUSIVE LANGUAGE LEARNING THROUGH WHATSAPP: A CASE STUDY ON TRAINEE TEACHERS AND ITALIAN L2 LEARNERS IN A MULTILINGUAL AND MULTICULTURAL BACKGROUND." Trabalhos em Linguística Aplicada 62, no. 1 (2023): 104–20. http://dx.doi.org/10.1590/010318138672210v6212023.

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ABSTRACT The aim of the present study is twofold: 1 to investigate the strategies used by a group of trainee teachers during the implementation via WhatsApp of pre-task activities inspired by the autobiographical approach; 2. to analyse whether and how learners show emotional engagement through online messages, referred here as the ability to express their own personal sphere in the host country’s language. The case study consists of the observation of 900 WhatsApp messages sent over a period of 39 days, aimed at carrying out 9 pre-task activities to enhance the intra-personal emotional sphere
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Bruno, B., M. Rotta, F. Patriarca, et al. "A Prospective Phase II Study on Tandem Autografting-Nonmyeloablative Allografting for Newly Diagnosed Myeloma: Final Results of the Gruppo Italiano Trapianto Midollo Osseo." Blood 110, no. 11 (2007): 3026. http://dx.doi.org/10.1182/blood.v110.11.3026.3026.

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Abstract The development of nonmyeloablative conditionings has recently reduced the transplant-related mortality (TRM) and extended the eligible age for transplantation up to 65–70 years. From January 2000 to June 2005, 106 newly diagnosed patients younger than 65 years were enrolled in a prospective phase II study at 15 Italian Centers. Fifty-eight were also previously described in a comparison of autografting with allografting based on a genetic randomisation (Bruno et al. N Engl J Med 2007). Here we report on a larger GITMO experience with a longer follow-up. Induction chemotherapy consiste
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Bengala, C., C. Zamagni, P. Pedrazzoli, et al. "Cardiac tolerability of trastuzumab in metastatic breast cancer (MBC) patients previously treated with high-dose chemotherapy (HDC) with autologous hemopoietic support: Retrospective analysis from Gruppo Italiano Trapianto Midollo Osseo (GITMO) Solid Tumor Working Party." Journal of Clinical Oncology 24, no. 18_suppl (2006): 10558. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.10558.

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10558 Background: HER-2 overexpression is associated to a poor prognosis in high-risk and MBC patients treated with HDC. HER-2 status is also a predictive factor of response to trastuzumab: when trastuzumab is administered in combination with or sequentially to chemotherapy, a significant DFS and/or survival improvement has been observed in HER2+ early and MBC. Unfortunately, in both settings, trastuzumab was associated with an increased risk of cardiac dysfunctions (CD). Patients and Methods: In order to evaluate the cardiac safety of trastuzumab after HDC, we have reviewed the clinical chart
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