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Artículos de revistas sobre el tema "Ileum"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 15 de junio de 2025

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1

Sarna, Sushil K. "Neuronal locus and cellular signaling for stimulation of ileal giant migrating and phasic contractions." American Journal of Physiology-Gastrointestinal and Liver Physiology 284, no. 5 (2003): G789—G797. http://dx.doi.org/10.1152/ajpgi.00451.2001.

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We investigated the neuronal locus, the role of PKC activation, and utilization of extracellular Ca2+ and intracellular Ca2+ release in smooth muscle cells for the generation of giant migrating contractions (GMCs) and rhythmic phasic contractions (RPCs) in intact normal and inflamed canine ileum. Calcitonin gene-related peptide (CGRP), administered close intra-arterially, stimulated GMCs at higher doses and RPCs at smaller doses. These effects were blocked by prior close intra-arterial infusions of CGRP8–37, atropine, hexamethonium, and TTX but not by tachykinin, serotonin, and histaminergic receptor subtype antagonists. Both types of contractions were blocked by verapamil in normal and inflamed ileums. Dantrolene and ruthenium red blocked only the RPCs in normal ileum but blocked both GMCs and RPCs in the inflamed ileum. PKC inhibition by chelerythrine blocked GMCs only in inflamed ileum but blocked RPCs in both normal and inflamed ileums. The inhibition of phospholipase C by neomycin blocked both RPCs and GMCs in normal and inflamed ileums. In conclusion, acetylcholine is the common neurotransmitter for the stimulation of both GMCs and RPCs, but the signaling cascades for their stimulation are partially divergent, and they differ also in the normal and inflamed states.

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2

NAKAGAWA, Tatsuro, Toshiyuki YOHDA, Tae MYUNG YOON, et al. "A CASE OF ILEUM ENDOMETRIOSIS PRESENTED WITH ILEUS." Journal of the Japanese Practical Surgeon Society 52, no. 3 (1991): 598–601. http://dx.doi.org/10.3919/ringe1963.52.598.

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3

Schadow, Claudia, Hanna Schmidt, Alexander Schorcht, and Frank Meyer. "Seltener klinischer Fall eines Dünndarm-Ileus in Folge eines invaginierten Meckel’schen Divertikels." DMW - Deutsche Medizinische Wochenschrift 143, no. 06 (2018): 407–10. http://dx.doi.org/10.1055/s-0044-101965.

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Zusammenfassung Anamnese und klinischer Befund Aufnahme eines 43-jährigen Patienten mit seit 2 Tagen bestehenden diffusen abdominellen Beschwerden anamnestisch (epigastrischer Beginn; keine abdominellen Voroperationen). Untersuchungen Gastroskopie und Abdomensonografie erbrachten nur eine geringgradige Gastritis, laborchemisch lediglich leichtgradige Leukozytose (10 610/µl). Nach 24 h klinischer Beobachtung bereits zunehmende Ileus-Symptomatik mit progredient geblähtem Abdomen, klingenden Darmgeräuschen und rezidivierendem, teils stuhligem Erbrechen. CT: intraluminaler Ileumtumor. Chirurgisch wurde die OP-Indikation gestellt. Diagnose Dringender Verdacht auf mechanischen Ileus aufgrund eines obstruierenden Dünndarmtumors mit geplanter frühelektiver Operation. Therapie In der Unterbauchlaparotomie Invagination im terminalen Ileum – nach Devagination wurde ein invaginiertes Meckel’sches Divertikel eruiert. Dieses wurde „wandbündig“ reseziert und das Ileum quer vernäht. Verlauf Postoperativ unauffällig. Folgerung Ein invaginiertes Meckel’sches Divertikel gehört zu den seltenen Ursachen für einen Dünndarm-Ileus bzw. ein unklares/akutes Abdomen beim Erwachsenen. Diese Ileus-Ursache sollte jedoch bei nicht voroperierten erwachsenen Patienten mit – wenn auch selten – in Betracht gezogen werden.

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4

Hendra Kastiaji and Imam Al Rasyidi. "Ileus Obstruktif: Laporan Kasus." Jurnal Kesehatan Amanah 7, no. 1 (2023): 40–45. http://dx.doi.org/10.57214/jka.v7i1.262.

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Ileus obstruktif adalah suatu keadaan yang menyebabkan isi usus tidak bisa melewati lumen usus sebagai akibat adanya sumbatan atau hambatan mekanik pada lumen usus. Tatalaksana yang tepat dan cepat pada pasien ileus obstruktif merupakan hal yang penting untuk mencegah prognosis yang buruk terhadap pasien. Pemeriksaan penunjang yang dapat dilakukan untuk membantu menegakkan diagnosa ileus obstruktif adalah foto polos abdomen 3 posisi. Segera setelah penegakkan diagnosa dapat dilakukan tindakan pembedahan berupa laparotomi eksplorasi. Kami melaporkan pasien laki-laki, 24 tahun, mengeluhkan nyeri perut, mual dan muntah, serta sulit buang air besar. Pemeriksaan abdomen menunjukkan distensi pada seluruh lapang abdomen dan terdapat nyeri tekan abdomen. Beberapa pemeriksaan penunjang meliputi pemeriksaan laboratorium dan radiologi dilakukan. Pasien di diagnosa dengan ileus obstruktif. Pasien dilakukan tindakan laparotomi eksplorasi dan reseksi anastomosis ileum, dan pada hari ke-8 rawatan post operasi laparotomi eksplorasi dan reseksi anastomisis ileum, pasien dinyatakan meninggal.

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5

Koeckeritz, Jane Large, Kathie Vanosdall Hopkins, and Alison Saricks Merrill. "ILEUM." Nurse Educator 29, no. 2 (2004): 75–79. http://dx.doi.org/10.1097/00006223-200403000-00010.

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6

Bratu, Dan, Radu Chicea, Tanasescu Ciprian, et al. "A rare case of ileus caused by ileum endometriosis." International Journal of Surgery Case Reports 26 (2016): 24–26. http://dx.doi.org/10.1016/j.ijscr.2016.06.023.

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7

TSUKAHARA, Hiroaki, Masahiro KURITA, Shuichi SEZAI, et al. "A case of ileum ulcer showing segmental mega-ilem." Nihon Naika Gakkai Zasshi 78, no. 3 (1989): 363–66. http://dx.doi.org/10.2169/naika.78.363.

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8

Hishikawa, Takanori, Shoji Oura, and Masafumi Tomita. "Successful Surgical Intervention of Strangulated Ileus with a Simple Cut of the External Iliac Vein without Vein Reconstruction." Case Reports in Gastroenterology 15, no. 3 (2021): 846–51. http://dx.doi.org/10.1159/000519198.

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A 67-year-old woman with epigastralgia was referred to our hospital. The patient had undergone hysterectomy, bilateral oophorectomy, omentectomy, and radical pelvic and para-aortic lymph node dissection for her ovarian cancer 6 years before. Despite the gastrointestinal decompression therapy under the presumed diagnosis of adhesive ileus, computed tomography scans taken 3 days after the onset of epigastralgia showed marked dilatation of the small intestine and an oval high-density mass, that is, thrombi, in the right femoral vein. Aggravation of ileus with the thrombi in the femoral vein made us to treat the patient with surgery. Intraoperative findings showed that the terminal ileum was strangulated by a gap between the exposed right external iliac vein and artery presumably formed by pelvic lymph node dissection. Distal ileum strangulated by the gap, however, showed no ischemic change with no surgically available peritoneum left around the external iliac vein. To prevent the pulmonary embolism and the recurrence of this type of ileus due to both the thrombi and the persistent gap, we released the strangulated ileum with a simple cut of the external iliac vein without vein reconstruction. The patient recovered uneventfully and was discharged on the 13th day after operation. The patient has been well with nominal right leg edema. In this situation, that is, internal hernia caused by external iliac vessels with thrombi in the femoral vein and no leg edema, a simple cut of the external iliac vein without vein reconstruction is a feasible treatment option.

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9

Stein, Raimund, and Jan Fichtner. "Ileum-Conduit." Aktuelle Urologie 53, no. 03 (2022): 279–88. http://dx.doi.org/10.1055/a-1804-9493.

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10

Stein, R., and J. Fichtner. "Ileum-Conduit." Aktuelle Urologie 44, no. 02 (2013): 151–60. http://dx.doi.org/10.1055/s-0029-1233523.

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11

Yamanaka, Hidetaka, Haruru Asamoto, Takahiko Ishizaka, et al. "A Case of Arteriovenous Malformation of Ileum Presented by Ileus." Japanese Journal of Gastroenterological Surgery 44, no. 4 (2011): 455–61. http://dx.doi.org/10.5833/jjgs.44.455.

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12

Woodrooffe, Koryse S., Chang Suk Moon, Chandrima Sinha, et al. "Tu1384 Meconium Ileus: Mucin Secretion in the Cystic Fibrosis Ileum." Gastroenterology 148, no. 4 (2015): S—875. http://dx.doi.org/10.1016/s0016-5085(15)32971-1.

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13

Yamauchi, Yoshiya, Noritaka Wakui, Yasutsugu Asai, et al. "Gallstone Ileus following Endoscopic Stone Extraction." Case Reports in Gastrointestinal Medicine 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/271571.

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An 85-year-old woman was an outpatient treated at Tokyo Rosai Hospital for cirrhosis caused by hepatitis B. She had previously been diagnosed as having common bile duct stones, for which she underwent endoscopic retrograde cholangiopancreatography (ERCP). However, as stone removal was unsuccessful, a plastic stent was placed after endoscopic sphincterotomy. In October 2012, the stent was replaced endoscopically because she developed cholangitis due to stent occlusion. Seven days later, we performed ERCP to treat recurring cholangitis. During the procedure, the stone was successfully removed by a balloon catheter when cleaning the common bile duct. The next day, the patient developed abdominal pain, abdominal distension, and nausea and was diagnosed as having gallstone ileus based on abdominal computed tomography (CT) and abdominal ultrasonography findings of an incarcerated stone in the terminal ileum. Although colonoscopy was performed after inserting an ileus tube, no stone was visible. Subsequent CT imaging verified the disappearance of the incarcerated stone from the ileum, suggesting that the stone had been evacuated naturally via the transanal route. Although it is extremely rare for gallstone ileus to develop as a complication of ERCP, physicians should be aware of gallstone ileus and follow patients carefully, especially after removing huge stones.

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14

Georgiev, IP, TM Georgieva, M. Pfaffl, HM Hammon, and JW Blum. "Insulin-like growth factor and insulin receptors in intestinal mucosa of neonatal calves." Journal of Endocrinology 176, no. 1 (2003): 121–32. http://dx.doi.org/10.1677/joe.0.1760121.

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Intestinal development is modified by age and nutrition, mediated in part by insulin-like growth factors (IGF-I, IGF-II) and insulin. We have investigated whether expression of IGF-I, IGF-II and insulin receptors (IGF-IR, IGF-IIR and IR; measured by real-time RT-PCR) and binding capacity (Bmax) of IGF-IR, IGF-IIR and IR in the mucosa of the small and large intestine of neonatal calves are modified by age and different feeding regimes. In experiment 1, pre-term (GrP) and full-term (GrN) calves (after 277 and 290 days of pregnancy respectively) were killed immediately after birth before being fed; a further group of full-term calves were fed for 7 days and killed on day 8 of life (GrC(1-3)). In experiment 2, full-term calves were killed on day 8 after being fed first-colostrum for 7 days (GrCmax), colostrum of the first six milkings for 3 days (GrC(1-3)) or milk-based formula for 3 days (GrF(1-3)). Intestinal sites differed with respect to expression levels of IGF-IR (duodenum>jejunum in GrC(1-3); ileum>colon, duodenum> or = jejunum in GrF(1-3)), IGF-IIR (colon>duodenum and ileum in GrN), and IR (lowest in ileum in GrP and CrN; highest in colon in GrC(1-3) and GrCmax). They also differed with respect to Bmax of IGF-IR (ileum and colon>duodenum and jejunum in GrP; ileum and colon>jejunum in GrN; colon>jejunum in GrC(1-3); lowest in jejunum in GrF(1-3)), IGF-IIR (duodenum and colon>jejunum and ileum in GrP; duodenum>ilem and colon>jejunum in GrN; duodenum, jejunum and colon>ileum in GrCmax, GrC(1-3), and GrF(1-3)) and IR (ileum>duodenum, jejunum and colon in GrCmax, GrC(1-3), and GrF(1-3)). There were significant differences between groups in the expression of IGF-IR (GrF(1-3)> GrCmax and GrC(1-3) in ileum), IGF-IIR (GrN>GrP and GrC(1-3) in colon; GrN>GrC(1-3) in jejunum and total intestine), and IR (GrCmax>GrF(1-3) in colon) and in the Bmax of IGF-IR (GrP>GrN in colon; GrCmax>GrF(1-3) in jejunum), IGF-IIR (GrN>GrP in duodenum, ileum and total intestine; GrN>GrC(1-3) in duodenum, ileum, colon and total intestine) and IR (GrN>GrP in total intestine; GrC(1-3)>GrN in ileum and total intestine). In addition, Bmax values of IGF-IR, IGF-IIR and IR were correlated with villus circumference, villus height/crypt depth and proliferation rate of crypt cells at various intestinal sites. There were marked differences in Bmax of IGF-IR, IGF-IIR and IR dependent on mRNA levels, indicating that differences in Bmax were the consequence of differences in posttranslational control and of receptor turnover rates. In conclusion IGF-IR, IGF-IIR and IR expressions and Bmax in intestinal mucosa were different at different intestinal sites and were variably affected by age, but not significantly affected by differences in nutrition. Receptor densities were selectively associated with intestinal mucosa growth.

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15

Jarbou, S. M., and F. A. Al Hammouri. "Gallstone ileus in the Jordanian Royal Medical Services in a 10-year period." Eastern Mediterranean Health Journal 6, no. 5-6 (2000): 1117–21. http://dx.doi.org/10.26719/2000.6.5-6.1117.

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Six patients [5 women and 1 man, with a median age of 71 years] were operated on for gallstone ileus in the 10-year period 1988-98. The diagnosis was made before operation in 2 patients. The obstructing stones were located in the terminal ileum in 3 patients and in the proximal ileum or jejunum in 3 patients. Choledochoduodenal fistula was present in all patients. A single-stage procedure [removal of the impacted stone, fistula repair and cholecystectomy]was performed in 1 patient, enterolithotomy alone in 4 patients and resection of part of the intestine where the stone was impacted with primary anastomosis performed in 1 patient. In the postoperative period, 2 patients developed infection of the wound and 2 patients developed deep vein thrombosis; 1 of these died of pulmonary embolism.

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16

MATSUI, Takanori, Masato KATAOKA, Youichi SUGITA, et al. "A CASE OF OBSTRUCTIVE ILEUS CAUSED BY ENDOMETORIOSIS IN THE ILEUM." Journal of the Japanese Practical Surgeon Society 56, no. 8 (1995): 1692–95. http://dx.doi.org/10.3919/ringe1963.56.1692.

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17

GOHONGI, Takeshi, Takesaburo OGATA, Yoritaka NAKANO, Hiroyuki IIDA, Naoto GUNJI, and Kazuo ORII. "A CASE OF ILEUS CAUSED BY ISCHEMIC ENTERITIS OF THE ILEUM." Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 70, no. 7 (2009): 2013–16. http://dx.doi.org/10.3919/jjsa.70.2013.

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18

Terada, Tadashi. "Large ectopic pancreas (Heinlich 3) of ileum causing intussusceptions and ileus." Human Pathology: Case Reports 1, no. 2 (2014): 29–30. http://dx.doi.org/10.1016/j.ehpc.2014.09.006.

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19

De Palma, G. D., G. Mastrobuoni, and G. Benassai. "Gallstone ileus: Endoscopic removal of a gallstone obstructing the lower ileum." Digestive and Liver Disease 41, no. 6 (2009): 446. http://dx.doi.org/10.1016/j.dld.2008.06.017.

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20

Wali, Luqman, Fahd Husain, Sharmarke Ali, et al. "Gallstone ileus with an enterovaginal fistula: a rare complication of pelvic radiotherapy." BJR|case reports 6, no. 4 (2020): 20200060. http://dx.doi.org/10.1259/bjrcr.20200060.

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Gallstone ileus is a rare cause of small bowel obstruction. Chronic gallstone irritation can lead to the formation of a cholecystoduodenal fistula, with gallstone impaction typically in the terminal ileum. Rarely gallstones can become impacted in other structures such as the colon or can even erode through the bowel. We present an unusual case of a gallstone ileus which resulted in the formation of an enterovaginal fistula, secondary to previous pelvic radiotherapy. Our case highlights the importance of considering fistula formation as a late complication of radiotherapy and how this can alter expected features of other pathologies, such as a gallstone ileus.

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21

Murat Yılmaz, Eyüp, Erdem Barış Cartı, and Altay Kandemir. "A rare cause of duodenal obstruction: Bouveret syndrome." Turkish Journal of Surgery 37, no. 2 (2021): 175–78. http://dx.doi.org/10.47717/turkjsurg.2021.3794.

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Gallstone ileus is a relatively rare pathology, most commonly obstructing the terminal ileum. Bouveret syndrome, leading to gastric outlet obstruction and seen with an incidence of less than 1%, is a syndrome met particularly in elderly patients and develops as the result of cholecysto-enteric fistula. In this report, it was aimed to present a 95-year-old case diagnosed with Bouveret syndrome.

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22

Gordon, Phillip V., Billie M. Moats‐Staats, Alan D. Stiles, and Wayne A. Price. "Dexamethasone Changes the Composition of Insulin‐like Growth Factor Binding Proteins in the Newborn Mouse Ileum." Journal of Pediatric Gastroenterology and Nutrition 35, no. 4 (2002): 532–38. http://dx.doi.org/10.1002/j.1536-4801.2002.tb07881.x.

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ABSTRACTBackgroundEarly postnatal glucocorticoid exposure accelerates the maturation of the bowel mucosa but results in bowel wall thinning in the newborn mouse ileum and increases the risk of focal ileal perforation in extremely premature infants. We have previously demonstrated a redistribution of insulin‐like growth factor‐I (IGF‐I) from the submucosa in control animals to the distal villi of those treated with early postnatal dexamethasone, implicating IGF‐I as an important mediator of dexamethasone's capacity to alter tissue growth. To investigate the possibility that IGF binding proteins (IGFBPs) might contribute to this process, we characterized the localization and abundance of IGFBP peptides and mRNAs in the same model.MethodsNewborn mice received daily intraperitoneal injections of dexamethasone (l μg/g) or phosphate‐buffered saline and then were euthanized on day 3 of life. Their ileums were harvested and prepared for microscopy. Tissue sections of ileum from both treatment conditions were processed in parallel for immunolocalization of each of the six IGFBP peptides and for in situ hybridization of each of the six IGFBP transcripts.ResultsTranscripts for IGFBP‐1, ‐2, and ‐3 were highly abundant and ubiquitous the ileal mucosa, whereas transcripts for IGFBP‐4, ‐5, and ‐6 were less abundant in epithelial cells. There were no differences in abundance between control and dexamethasone‐treated ileum with regard to mRNA localization or abundance for IGFBP‐1, ‐2, ‐3, and ‐6. In contrast, mRNA transcripts for IGFBP‐4 and ‐5 were modestly increased with dexamethasone treatment (although only IGFBP‐4 was significant). Strikingly different patterns of IGFBP immunolocalization were observed between control and dexamethasone‐treated animals. IGFBP‐1, ‐2, ‐3, and ‐5 were not detected in control ileum, whereas IGFBP‐4 and ‐6 were both present in the mucosa. In contrast, dexamethasone treatment resulted in dramatic mucosal increases in IGFBP‐2, ‐3, ‐4, and ‐5, paralleling the changing distribution of IGF‐I that we previously reported.ConclusionTaken together, these findings further implicate the IGF system as an important participant in dexamethasone‐induced maturation in the newborn mouse ileum.

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23

Mao, Yi-Hu, Li-Bin Huang, Qi Jia, et al. "Rare “ileum–ileum–colon type” adult intussusception caused by Meckel’s diverticulum inversion: A case report." Medicine 104, no. 1 (2025): e41237. https://doi.org/10.1097/md.0000000000041237.

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Rationale: Ileum–ileum–colon intussusception constitutes a small proportion of the classification of intussusception. Both adult intussusception and Meckel’s diverticulum are rare clinical entities, with few reports documenting Meckel’s diverticulum inversion leading to ileum–ileum–colon intussusception in adults. Patient concerns: A 33-year-old Chinese male presented with intermittent abdominal pain persisting for 1 month, that had intensified over the preceding day. Diagnoses: Abdominal computed tomography revealed intussusception, suspected to be secondary to a small intestinal lipoma. Interventions: Emergency laparotomy was performed, during which the ileum, located approximately 70 cm from the ileocecal region, was found to be invaginated into the terminal ileum and subsequently into the ascending colon, reaching the hepatic flexure. An inverted Meckel’s diverticulum was at the forefront of the intussusception. Surgical resection of the diverticulum, terminal ileum, and cecum was performed, followed by an end-to-side anastomosis of the ileum and colon. Outcomes: The patient was discharged on postoperative day 7 without complications. During a 1-month follow-up, the patient reported no discomfort and exhibited normal bowel movements. Lessons: Adult intussusception of the “ileum–ileum–colon type” resulting from inverted Meckel’s diverticulum is exceedingly rare and poses challenges for preoperative diagnosis. Prompt surgical intervention can lead to favorable outcomes in patients. During surgery, the initial step should involve attempting reduction of the intussusception while ensuring that the intestine is preserved as much as possible to maintain intestinal function.

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24

Güzel, Gökmen, and Muhammer Ergenç. "Recurrent Ileo-ileal Intussusception Caused by Inflammatory Fibroid Polyp: A Rare Case Report." Archives of Iranian Medicine 26, no. 6 (2023): 355–57. http://dx.doi.org/10.34172/aim.2023.53.

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An inflammatory fibroid polyp is a rare benign lesion of the gastrointestinal tract, which can cause obstruction or intussusception when it reaches a large diameter. We present a case of a 46-year-old female admitted to our clinic with recurrent ileus attacks. We performed segmental resection of the small bowel due to a 3-cm pedunculated polypoid lesion located in the terminal ileum that caused ileo-ileal intussusception and whose pathology was reported as an inflammatory fibroid polyp. In adults presenting with ileus, the possibility of intussusception should be kept in mind.

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Zhang, Na, Qineng Ping, Guihua Huang, Xiuzhen Han, Yanna Cheng, and Wenfang Xu. "Transport Characteristics of Wheat Germ Agglutinin-Modified Insulin-Liposomes and Solid Lipid Nanoparticles in a Perfused Rat Intestinal Model." Journal of Nanoscience and Nanotechnology 6, no. 9 (2006): 2959–66. http://dx.doi.org/10.1166/jnn.2006.425.

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Wheat germ agglutinin (WGA) modified liposomes and solid lipid nanoparticles (SLNs) were evaluated for improving intestinal absorption of insulin. In an in situ local intestinal perfusion experiment, formulations containing 100 IU/kg insulin were administered to the duodenum, jejunum, and ileum of fasted rats. As hypothesized, ileum was the best intestinal location for the absorption of insulin-containing liposomes. Serum insulin concentrations decreased for the various formulations in different absorption sites according to the following trends: Duodenum > ileum > jejunum for WGA-modified insulin-containing liposomes; duodenum > jejunum > ileum for WGA-modified insulin-containing SLNs; ileum > jejunum > duodenum for insulin-containing liposomes; ileum > duodenum > jejunum for insulin-containing SLNs; and duodenum ≥ ileum > jejunum for aqueous solution of insulin. These results imply that the nanoparticle type and delivery site were important factors with respect to increasing the bioavailability of insulin following oral administration. The proteolytic degradation as well as the epithelial permeability were primary determinants influcing insulin mucosal absorption.

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Satya Prakash, Shalinee, Azaz Akhtar Siddiqui, and Moeenuddeen. "An unusual case of small bowel obstruction due to multiple primary enteroliths: a case report." International Surgery Journal 11, no. 11 (2024): 1903–6. http://dx.doi.org/10.18203/2349-2902.isj20243254.

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Enteroliths are caused by intestinal stasis or gut hypomotility. It can be primary enteroliths which is produced within the intestine or secondary where stones are migrated from outside gastrointestinal tract like gall stone ileus. A 57-year-old lady presented with complaints of pain in abdomen with constipation. On abdomen X-ray there was 3 large laminated calcified bodies in pelvis. On ultrasound there were gall stones present and hyperechoic bodies present in bowel loops, urinary bladder was empty. On CECT 3 enteroliths present in ileum causing small bowel obstruction. Patient was planned for diagnostic laparoscopy where focal bowel dilatation present at mid ileum. There was no cholecystoenteric fistula present. Laparoscopy cholecystectomy along with laparoscopy assisted extracorporeal resection and anastomosis of involved bowel with removal of 3 enteroliths of size 4×4 cm done. Small enteroliths can pass spontaneously but large and impacted enteroliths needs surgical intervention.

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27

Pulak, Azad, Rizvi Yasir Sultan, Jha Lakshmi Kant, Tyagi Pranav, Jain Sachin, and Malik Twinkle. "Gallstone Ileus: A Rare Case of Intestinal Obstruction, Presented in a Chronic Kidney Disease Patient on Haemodialysis." Journal of Clinical Nephrology 9, no. 2 (2025): 027–30. https://doi.org/10.29328/journal.jcn.1001149.

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The prevalence of gallbladder stones is higher in Chronic Kidney Disease (CKD) patients and it has been shown to increase with the advancement of the disease stage, from 7.7% in stage 1% to 21.3% in stage 5. Gallstone ileus is a rare complication which presents in just 0.3% - 0.5% of patients with cholelithiasis. A 61-year-old female patient, with a known case of CKD on maintenance hemodialysis, (thrice a week) with primary disease of hypertensive and diabetic nephropathy; presented with multiple episodes of loose stool, vomiting, and diffuse abdominal pain for 2 days. Abdomen Ultrasonography (USG) was suggestive of intestinal obstruction. CT abdomen with oral contrast revealed grossly dilated jejuna loops with air-fluid levels and transition zone in the pelvis, in distal jejunal loops/proximal ileum with ovoid intraluminal filling defect cystic polyp and collapsed bowel loops. The patient underwent exploratory laparotomy in view of persistent small bowel obstruction. Resection and anastomosis of the mass-bearing small bowel segment were performed. On cutting and opening the specimen, a large stone was revealed. This gallstone was causing bowel obstruction-gall stone ileus. A gallstone 2.6 cm x 2.1 cm has traversed through a cholecysto-duodenal fistula and got stuck in the proximal ileum, causing small bowel obstruction. The lesson learned is uraemia can cause gastrointestinal symptoms like anorexia, abdominal pain, vomiting, and ileus and hence mimic serious differentials of the acute abdomen like gallstone ileus. Thus no stone should be left unturned especially when the prevalance of gallstones is high in chronic kidney disease patients.

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NOZAKI, Reiji, Satoshi YODONAWA, Akinori KATO, Hiromichi ITO, Susumu YOSHIDA, and Isao OGAWA. "A CASE OF INFLAMMATORY MYOFIBROBLASTIC TUMOR OF THE ILEUM PRESENETING WITH ILEUS." Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 72, no. 7 (2011): 1763–67. http://dx.doi.org/10.3919/jjsa.72.1763.

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29

Barrett, T. A., M. W. Musch, and E. B. Chang. "Chemotactic peptide effects on intestinal electrolyte transport." American Journal of Physiology-Gastrointestinal and Liver Physiology 259, no. 6 (1990): G947—G954. http://dx.doi.org/10.1152/ajpgi.1990.259.6.g947.

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The bacterial-derived chemotactic peptide N-formylmethionyl-leucyl-phenylalanine (fMLP) increases short-circuit current (Isc) and arachidonic acid metabolism (AAM) in rabbit ileum and distal colon. Serosal (s) or mucosal (m) addition of fMLP transiently increases Isc. Half-maximally effective dose and maximal increases in Isc were 32 nM and 84 microA/cm2 in ileum and 234 nM and 80 microA/cm2 in colon, respectively. Piroxicam, a cyclooxygenase inhibitor, diminished the Isc response by 97% in colon and 69% in ileum. Changes in Isc were dependent on Cl- and HCO3- in the bathing media. In ileum, fMLP inhibited m-to-s 36Cl- fluxes and stimulated s-to-m 36Cl- fluxes. These changes in Cl- flux were also inhibited by piroxicam. fMLP stimulated prostaglandin E2 (PGE2) release in intact tissue and in isolated subepithelial components. Increased tissue adenosine 3',5'-cyclic monophosphate levels were detected in intact tissue but not in isolated components. Previous desensitization of ileum to PGE1 inhibited fMLP stimulation of Isc in ileum by 88%. Desensitization to fMLP in ileum failed to alter the effect of PGE1 (10 microM) on Isc. In isolated microsomal membranes of ileal enterocytes, fMLP binding sites could not be demonstrated, suggesting that fMLPs action was initially mediated via stimulation of nonepithelial cell cyclooxygenase activity. The above results indicate that fMLP stimulates net secretion in both ileum and colon probably by the activation of AAM.

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30

Anshari, Zaim, Chrismis Novalinda Ginting, Linda Chiuman, and Yuliani Mardiati Lubis. "PENGARUH EKSTRAK KULIT BUAH MANGGIS (Garcinia Mangostana Linn) TERHADAP PERISTALTIK ILEUM TERPISAH MARMOT JANTAN SEBAGAI ANTI DIARE." Jurnal Penelitian Farmasi & Herbal 2, no. 1 (2019): 9–18. http://dx.doi.org/10.36656/jpfh.v2i1.73.

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Objective: to determine the effect of mangosteen peel extract (Garcinia mangostana Linn) on ileal peristalsis separate male guinea pigs as diarrhea. Results: t-independent test, the difference: Contraction of ileum Acethlcholin with Atropine + Acethylcholin is 6.333 compared to Acethylcholin with extract + Acethylcholin is 8,500 with ANOVA test P value meaning the difference between the two contractions of the ileum is significant. The t-independent test results are the difference: Contraction of ileum Histamine with Diphenhidramine + Histamine is 8.333 compared to Histamine with extract + Histamine is 10.833 with ANOVA test P value meaning the difference between the two contractions of the ileum is significant. The results of the t-independent test are the difference: Contraction of the Barrium ileum with Papaverine + Barrium is 2,500 compared to the contraction of Barrium ileum with extract + Barrium is 2,500 with ANOVA test P value meaning that there is no difference between the two contractions of the ileum. From the three experimental groups, it was concluded that the extract worked similar to Papaverine. Cecilia's study, fruit skin extract can be used as diarrhea in Diare Effect of Mangosteen Ethanol Extract of Oleum ricini-induced Webster Swiss Mice.

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Sinaga, Erikson, Nahitma Ginting, and Edy Suwarso. "Uji Aktivitas Antikejang Ekstrak Etanol Daun Titanus (Leea Aequata L.) Terhadap Ileum Marmut Terpisah (Cavia Porcellus) Secara In Vitro." Talenta Conference Series: Tropical Medicine (TM) 1, no. 1 (2018): 320–30. http://dx.doi.org/10.32734/tm.v1i1.66.

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Titanus (Leea aequata L.) merupakan tumbuhan dari suku leeaceae yang digunakan dalam pengobatan tradisional di daerah Tanah Karo, Provinsi Sumatera utara, sebagai obat luka dan obat anti tetanus. Salah satu tanda utama dari penyakit tetanus adalah spasme otot atau kejang disebagian atau seluruh tubuh. Penelitian ini bertujuan untuk mengetahui efek antikejang berupa relaksasi dari ekstrak etanol daun titanus terhadap kontraksi ileum marmut terisolasi yang dikontrasikan dengan asetilkolin. Penelitian ini dilakukan secara in vitro menggunakan alat organ bath. Tahapan penelitian adalah persiapan bahan dan pengujian efek relaksasi ileum terpisah. Parameter yang diukur dalam penelitian ini adalah relaksasi otot polos ileum terpisah. Sebelum dilakukan pengujian, ileum marmut terpisah diekuilibrasi selama 45 menit sampai diperoleh kondisi yang stabil didalam larutan tyrode dengan suhu 37o C yang diaerasi dengan gas karbogen (O2:CO2) 95% : 5%. Pengujian efek relaksasi dilakukan setelah ileum marmut dikontraksi dengan asetilkolin, kemudian masing masing ileum diberikan konsentrasi kumulatif ekstrak daun titanus dan atropin sulfat . Hasil pengujian yang diperoleh menunjukkan bahwa pemberian ekstrak etanol daun titanus memiliki efek relaksasi. Ekstrak etanol daun titanus pada konsentrasi 2,5mg/ml (105,4203±2,9151) mempunyai kemampuan yang tidak berbeda dengan atropin sulfat 1 x 10-5 (113,9796±4,5825) dalam menurunkan kontraksi otot polos ileum yang diinduksi oleh asetilkolin 1,889 x 10-4 M (p>0,005). Jadi dapat disimpulkan bahwa ekstrak etanol daun titanus mempunyai efek relaksasi terhadap otot polos ileum terpisah dengan kemampuan yang tidak jauh berbeda dengan atropin sulfat. Titanus (Leeaaequata L.) is a plant from Leeaceae family used in traditional medication in Tanah Karo, North Sumatera as wound and anti-tetanus medicine. One of the main signs of tetanus is muscle spasm or seizure in some or all parts of body. This research aimed to evaluatethe anti-seizure effect of titanus leaves ethanol extractsuch as relaxation isolated ileum of marmot which was contacted with acetylcholine. This research was conducted byin vitro studyusing organ bath instrument. The stages of this research were the material preparation and isolated ileum relaxation effect evaluation. The parameter measured in this research was the isolated ileum smooth muscle relaxation. Before the test, isolated marmot ileum was equilibrated for 45 minutes until the stable condition in tyrode solution was obtained at 37°C temperature which aerated with carbogen gas (O2:CO2) 95%:5%. The relaxation effect test was conducted aftermarmot ileum was contracted with acetylcholine, and then, titanus leaves extract and atropine sulfate were added to each ileumswith cumulative concentration. The result indicated that the titanus leaves ethanol extract had relaxation effect. Titanus Leaves ethanol extract in 2.5 mg/ml concentration (105.4203±2.9151) had the same ability as atropine sulfate 1x10-5 (113.9796±4.5825)in decreasing the ileum smooth muscle contraction induced with acetylcholine 1.889x10-4 M (p>0.005).It could be concluded that titanus leaves ethanol extract hasrelaxation effect to isolated ileum smooth muscle and it was not so different with atropine sulfate.

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Lan, Ruixia, Qingqing Chang, Linlin Wei, and Zhihui Zhao. "The Protect Effects of Chitosan Oligosaccharides on Intestinal Integrity by Regulating Oxidative Status and Inflammation under Oxidative Stress." Marine Drugs 19, no. 2 (2021): 57. http://dx.doi.org/10.3390/md19020057.

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The aim of this study was to evaluate the effects of the dietary supplementation of chitosan oligosaccharides (COS) on intestinal integrity, oxidative status, and the inflammation response with hydrogen peroxide (H2O2) challenge. In total, 30 rats were randomly assigned to three groups with 10 replications: CON group, basal diet; AS group, basal diet + 0.1% H2O2 in drinking water; ASC group, basal diet + 200 mg/kg COS + 0.1% H2O2 in drinking water. The results indicated that COS upregulated (p < 0.05) villus height (VH) of the small intestine, duodenum, and ileum; mucosal glutathione peroxidase activity; jejunum and ileum mucosal total antioxidant capacity; duodenum and ileum mucosal interleukin (IL)-6 level; jejunum mucosal tumor necrosis factor (TNF)-α level; duodenum and ileum mucosal IL-10 level; the mRNA expression level of zonula occludens (ZO)-1 in the jejunum and ileum, claudin in the duodenum, nuclear factor-erythroid 2-like 2 in the jejunum, and heme oxygenase-1 in the duodenum and ileum; and the protein expression of ZO-1 and claudin in jejunum; however, it downregulated (p < 0.05) serum diamine oxidase activity and D-lactate level; small intestine mucosal malondialdehyde content; duodenum and ileum mucosal IL-6 level; jejunum mucosal TNF-α level; and the mRNA expression of IL-6 in the duodenum and jejunum, and TNF-α in the jejunum and ileum. These results suggested COS could maintain intestinal integrity under oxidative stress by modulating the intestinal oxidative status and release of inflammatory cytokines.

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Erginel, Basak, Feryal Gun Soysal, Huseyin Ozbey, et al. "Small Bowel Obstruction due to Anomalous Congenital Bands in Children." Gastroenterology Research and Practice 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/7364329.

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Introduction. The aim of the study was to evaluate our children who are operated on for anomalous congenital band while increasing the awareness of this rare reason of intestinal obstruction in children which causes a diagnostic challenge.Patients and Methods. We retrospectively reviewed the records of fourteen children treated surgically for intestinal obstructions caused by anomalous congenital bands.Results. The bands were located between the following regions: the ascending colon and the mesentery of the terminal ileum in 4 patients, the jejunum and mesentery of the terminal ileum in 3 patients, the ileum and mesentery of the terminal ileum in 2 patients, the ligament of Treitz and mesentery of the jejunum in one patient, the ligament of Treitz and mesentery of the terminal ileum in one patient, duodenum and duodenum in one patient, the ileum and mesentery of the ileum in one patient, the jejunum and mesentery of the jejunum in one patient, and Meckel’s diverticulum and its ileal mesentery in one patient. Band excision was adequate in all of the patients except the two who received resection anastomosis for intestinal necrosis.Conclusion. Although congenital anomalous bands are rare, they should be considered in the differential diagnosis of patients with an intestinal obstruction.

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Tarteeb, Aya Wael, and Salim Salih Ali Al-Khakani. "Morphological and Histochemical Study of Jejunum and Ilium in Post Hatching of (Columba Livia) and Adult." SAR Journal of Anatomy and Physiology 6, no. 03 (2025): 87–98. https://doi.org/10.36346/sarjap.2025.v06i03.007.

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These results found differences in the jejunum and ilium of post hatching and adult Columba Livia in terms of morphological and histochemical aspects. the jejunum is longest part of small intestine and it was cone shape, it is starting at the proximal end of ascending duodenum to the ileum, it was consisted of centripetal, centrifugal coli and central flexure called spiral loop and suspended by mesentery called mesojejunum. It reddish- brown color. the ileum is third and short part of small intestine reddish color and it is continuing with jejunum to the end of ileo-cecal junction. Histological, the jejunum and ilium was consisting of four layer mucosa, sub-mucosa, muscularis, serosa. The tunica mucosa consisted from of villi, lamina propria and muscularis mucosa, the villi was finger like and not-branched, each villus was covered by simple columnar epithelium with goblet cells. The crypt of lieberkuhn also called intestinal gland were located in the basal of each villus. The thickness of tunica mucosa of jejunum in post and adult was high at level P˂0.05 vs thickness of tunica mucosa of ilium in post and adult. The tunica sub-mucosa was thin layer that form connective tissue and collagen fiber. The tunica muscularis was thick layer made from inner circular layer and outer longitudinal layer, the thickness of muscular of jejunum in post was high at level P˂0.05 vs adult. While the thickness of ilium in adult was high at the level P˂0.05 Vs post hatching. The serosa layer was thin of simple epithelium layer which contain blood vessels, nerve and adipose tissue.

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35

Nazari, Matthew, Alice Lee, Jared Rosenblum, Tilak Baba, and Samuel Kallus. "Eighteen Month Interval Growth of Terminal Ileal Primary Adenocarcinoma: A Consideration for Current Screening Guidelines." Case Reports in Gastroenterology 11, no. 3 (2017): 780–85. http://dx.doi.org/10.1159/000485238.

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Primary adenocarcinoma of the small intestine comprises one of the rarest gastrointestinal malignancies. Further, the terminal ileum is very seldom implicated. This entity occurs sporadically and evades traditional colonoscopic evaluation in which the terminal ileum is not visualized. Herein, a case of interval development of primary terminal ileal adenocarcinoma over a 2-year period is reported as followed by direct endoscopic and colonoscopic visualization. This case demonstrates cecal involvement not found on initial evaluation without the provision of terminal ileum intubation. Relevant guidelines regarding the evaluation of the terminal ileum in routine colonoscopy are reviewed.

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Öztürk, Yusuf, V. Melih Altan, Nuray Yıdızoğlu-Arı, and Orhan Altınkurt. "Bradykinin receptors in intestinal smooth muscles and their post-receptor events related to calcium." Mediators of Inflammation 2, no. 4 (1993): 309–15. http://dx.doi.org/10.1155/s0962935193000432.

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The effects of trifluoperazine and verapamil on bradykinin- and des-Arg9-bradykinin induced responses of isolated rat duodenum and guinea-pig ileum were investigated to elucidate post-bradykinin receptor events. Verapamil and trifluoperazine inhibited bradykinin induced relaxations and contractions and des-Arg9- bradykinin induced contractions in rat duodenum. Bradykinin induced contractions of ileum were also inhibited by trifluoperazine and. verapamil. Since non-competitive affinity constants of trifluoperazine and verapamil for the relaxant responses to bradykinin in duodenum and for the contractile responses to bradykinin in ileum are different, post-bradykinin receptor events related to calcium may be different in ileum and duodenum. In addition, affinity constants of bradykinin in guinea-pig ileum and rat duodenum are also disparate suggesting the presence of different types of bradykinin B2receptors in these two organs.

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37

Gschwend, Jürgen. "Ileum-Neoblase nach Hautmann." Aktuelle Urologie 52, no. 02 (2021): 181–95. http://dx.doi.org/10.1055/a-1296-2852.

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Gschwend, J. "Ileum-Neoblase nach Hautmann." Aktuelle Urologie 46, no. 02 (2015): 159–73. http://dx.doi.org/10.1055/s-0035-1549286.

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Tu, R. K., M. I. Fagerholm, and T. F. Warner. "Varix of the ileum." American Journal of Roentgenology 158, no. 4 (1992): 917–18. http://dx.doi.org/10.2214/ajr.158.4.1546616.

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Mecklenburg, Ingo, Andreas Probst, and Helmut Messmann. "Thumbprints in the Ileum." Gastroenterology 140, no. 5 (2011): 1400–1698. http://dx.doi.org/10.1053/j.gastro.2010.04.066.

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41

Burkhard, F., U. Studer, H. Danuser, and E. Zingg. "Ileum-Neoblase nach Studer." Aktuelle Urologie 46, no. 03 (2015): 249–60. http://dx.doi.org/10.1055/s-0035-1554719.

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42

Gschwend, J. "Ileum-Neoblase nach Hautmann." Aktuelle Urologie 40, no. 06 (2009): 367–82. http://dx.doi.org/10.1055/s-2009-1233500.

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43

Burkhard, F., G. Thalmann, U. Studer, M. Schumacher, H. Danuser, and E. Zingg. "Ileum-Neoblase nach Studer." Aktuelle Urologie 41, no. 01 (2010): 67–79. http://dx.doi.org/10.1055/s-0029-1233501.

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Barańczyk-Kuźma, A., and A. Ciszewska-Pilczyńska. "Human ileum phenol sulfotransferase." Biochemical Pharmacology 38, no. 17 (1989): 2927–30. http://dx.doi.org/10.1016/0006-2952(89)90452-8.

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Madara, James L. "Terminal ileum or colon?" Gastroenterology 94, no. 1 (1988): 251. http://dx.doi.org/10.1016/0016-5085(88)90655-5.

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46

Kortieva, A. T., V. S. Krushelnitskiy, S. A. Gabriel, V. Yu Dynko, and A. Ya Guchetl. "Vascular malformation of ileum." Experimental and Clinical Gastroenterology, no. 10 (January 18, 2023): 180–82. http://dx.doi.org/10.31146/1682-8658-ecg-206-10-180-182.

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The aim of the study is to observe a patient with vascular malformation of the ileum complicated by recurrent bleeding. Materials and methods: the article presents a clinical case of small intestine bleeding from ileum angiectasia in a 64-year-old patient. At the patient's place of residence, a video capsule endoscopy of the gastrointestinal tract was performed, angiectasia of the ileum was detected, from which fresh blood was received. Upon admission, the patient has iron deficiency anemia, and hematocheesia. In our institution, the patient underwent diagnostic egophagogastroduodenoscopy, video colonoscopy, balloon-assisted enteroscopy (BAE). According to BAE, vascular malformation with a diameter of up to 10 mm is viuzalized in the ileum Results: The patient underwent endoscopic treatment: one endoclypse was applied to the identified vascular malformation. Conclusion: The capabilities of clinicians in the differential diagnosis of pathological conditions of the small intestine are enhanced by the availability of modern equipment in medical and preventive institutions, as well as to perform minimally invasive treatment, reducing the rehabilitation time due to the reduction of surgical trauma.

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47

Kortieva, A. T., V. S. Krushelnitskiy, S. A. Gabriel, V. Yu Dynko, A. Ya Guchetl, and E. S. Babenko. "Vascular malformation of ileum." Experimental and Clinical Gastroenterology, no. 8 (January 18, 2023): 195–97. http://dx.doi.org/10.31146/1682-8658-ecg-204-8-195-197.

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The aim of the study is to observe a patient with vascular malformation of the ileum complicated by recurrent bleeding. Materials and methods: the article presents a clinical case of small intestine bleeding from ileum angiectasia in a 64-year-old patient. At the patient's place of residence, a video capsule endoscopy of the gastrointestinal tract was performed, angiectasia of the ileum was detected, from which fresh blood was received. Upon admission, the patient has iron deficiency anemia, and hematocheesia. In our institution, the patient underwent diagnostic egophagogastroduodenoscopy, video colonoscopy, balloon-assisted enteroscopy (BAE). According to BAE, vascular malformation with a diameter of up to 10 mm is viuzalized in the ileum Results: The patient underwent endoscopic treatment: one endoclypse was applied to the identified vascular malformation. Conclusion: The capabilities of clinicians in the differential diagnosis of pathological conditions of the small intestine are enhanced by the availability of modern equipment in medical and preventive institutions, as well as to perform minimally invasive treatment, reducing the rehabilitation time due to the reduction of surgical trauma.

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48

Cao, S., P. Deepak, and M. Colonna. "DOP41 Mucosal single-cell profiling of Crohn's-like disease of the pouch reveal unique pathogenesis and therapeutic targets." Journal of Crohn's and Colitis 18, Supplement_1 (2024): i144—i146. http://dx.doi.org/10.1093/ecco-jcc/jjad212.0081.

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Abstract Background After restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC), a subset of patients develop Crohn’s-like disease of the pouch (CDP), a chronic inflammatory condition that affects both the pouch body and extra-pouch organs including the pre-pouch ileum. The cellular and molecular identities of CDP are unknown, and its diagnosis and treatment remain challenging. To define the pathophysiology of CDP, we examined mucosal cells from patients after IPAA with and without CDP using single cell analyses. Methods Endoscopic samples from the pouch body and pre-pouch ileum of 50 patients with an IPAA were collected for single-cell RNA sequencing (scRNA-seq) or mass cytometry (or CyTOF). We analyzed immune and non-immune cells from both pouch body and pre-pouch ileum of patients with normal pouch/ileum and CDP using scRNA-seq. CyTOF was performed on mucosal immune cells from independent cohorts of patients with normal pouch/ileum, CDP, and pouchitis. Mucosal samples from patients with familial adenomatous polyposis (FAP) after colectomy and pouch formation were also analyzed by CyTOF. ScRNA-seq and CyTOF findings were independently validated using immunohistochemistry. Results We revealed distinct cell clusters in normal pouch body versus normal pre-pouch ileum in UC patients. Colitogenic immune cells expanded in normal UC pouch body compared to normal FAP pouch body. Compared to normal pouch/ileum, CDP pouch/ileum exhibited expanded TCR clonotypes, elevated Th17 signaling, and diminished T cell exhaustion markers. Elevated plasma cells, inflammatory fibroblasts and monocytes were noted in CDP pouch/ileum (Figure 1). CDP also harbored elevated Th17-inducing cytokines such as IL23, IL1B, and IL6 produced by myeloid cells. ScRNA-seq and CyTOF identified increased CD14+TREM1+ pathogenic monocytes in both pouch body and pre-pouch ileum of CDP. Ligand-receptor analysis further revealed a stromal – myeloid – lymphocyte circuit in CDP. Integrated analysis showed that upregulated immune mediators in CDP tissues were similar to those in CD and pouchitis, but not UC. In addition, the pouch body and pre-pouch ileum of CDP exhibited prominent activation of the unfolded protein response (UPR) across all major immune and non-immune cell compartments (Figure 2), which was not present in UC, CD or pouchitis based on reanalysis of published databases. Conclusion CDP demonstrates altered immune and non-immune cell populations/states in the pouch body and pre-pouch ileum. CDP represents a distinct entity of inflammatory bowel disease with extensive UPR activation, a unique feature that may serve as novel diagnostic markers and therapeutic targets using ER stress-alleviating agents including chemical chaperones.

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Janež, Jurij. "Bolus ileus-an occasional cause of small bowel obstruction-case report." International Journal of Research in Medical Sciences 5, no. 12 (2017): 5447. http://dx.doi.org/10.18203/2320-6012.ijrms20175471.

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A food bolus can be an occasional cause of small bowel obstruction. Especially older and senile patients are at higher risk for developing a bolus ileus. Certain pathological conditions are associated with a higher risk for developing a bolus ileus, such as duodenal and small bowel diverticula. In this paper is presented a case of a 68-year-old female patient with food bolus, that caused a mehanical small bowel obstruction. The abdominal computed tomography scan before surgery did not show the precise cause of intestinal obstruction. During surgery we found a big grape in the distal ileum, which was removed through enterotomy. Further postoperative course was uneventful.

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Bringhentti, Elouisa, Stephanie Carvalho Borges, Camila Quaglio Neves, and Nilza Cristina Buttow. "Remote organs respond differently to curcumin treatment after intestinal ischemia/reperfusion injury." Research, Society and Development 9, no. 11 (2020): e1519119660. http://dx.doi.org/10.33448/rsd-v9i11.9660.

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We aimed investigate the effects of 45 min of ischemia followed by 72 h of intestinal reperfusion (IR) in the ileum, liver, lungs, and kidneys in Wistar rats and the responses of these organs to curcumin treatment. Ischemia was induced by occluding the superior mesenteric artery. Rats were treated orally with 40 mg/kg curcumin. We analyzed oxidative stress and inflammation in the ileum, liver, lungs, and kidneys. Intestinal IR led to a reduction of reduced glutathione levels in the intestine, lungs, and kidneys and increased lipid hydroperoxide levels in all organs. An increase in the enzymatic activity of catalase was observed in all organs, and an increase in superoxide dismutase activity was observed in the ileum and lungs. Glutathione s-transferase levels increased only in the kidneys. Myeloperoxidase increased in all four organs, and n-acetyl-glycosaminidase increased only in the ileum and lungs. Curcumin prevented all of the changes in the ileum and liver. In the lungs, curcumin had no effect on n-acetyl-glycosaminidase. Curcumin did not prevent the changes in reduced glutathione, lipid hydroperoxides, or myeloperoxidase in the kidneys. Intestinal IR caused oxidative stress and inflammation in the ileum, lungs, and kidneys and to a lesser degree in the liver. Because of its systemic distribution, curcumin prevented changes mainly in the ileum, lungs, and liver and to a lesser degree in the kidneys.

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