Literatura académica sobre el tema "Intraspinal Microstimulations"

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Artículos de revistas sobre el tema "Intraspinal Microstimulations"

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Pikov, V. "Clinical Applications of Intraspinal Microstimulation". Proceedings of the IEEE 96, n.º 7 (julio de 2008): 1120–28. http://dx.doi.org/10.1109/jproc.2008.922583.

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Snow, S., K. W. Horch y V. K. Mushahwar. "Intraspinal Microstimulation using Cylindrical Multielectrodes". IEEE Transactions on Biomedical Engineering 53, n.º 2 (febrero de 2006): 311–19. http://dx.doi.org/10.1109/tbme.2005.857638.

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Sunshine, Michael D., Comron N. Ganji, Paul J. Reier, David D. Fuller y Chet T. Moritz. "Intraspinal microstimulation for respiratory muscle activation". Experimental Neurology 302 (abril de 2018): 93–103. http://dx.doi.org/10.1016/j.expneurol.2017.12.014.

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Khaled, Imad, Salma Elmallah, Cheng Cheng, Walied A. Moussa, Vivian K. Mushahwar y Anastasia L. Elias. "A Flexible Base Electrode Array for Intraspinal Microstimulation". IEEE Transactions on Biomedical Engineering 60, n.º 10 (octubre de 2013): 2904–13. http://dx.doi.org/10.1109/tbme.2013.2265877.

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Zimmermann, Jonas B., Kazuhiko Seki y Andrew Jackson. "Reanimating the arm and hand with intraspinal microstimulation". Journal of Neural Engineering 8, n.º 5 (10 de agosto de 2011): 054001. http://dx.doi.org/10.1088/1741-2560/8/5/054001.

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Toossi, Amirali, Dirk G. Everaert, Austin Azar, Christopher R. Dennison y Vivian K. Mushahwar. "Mechanically Stable Intraspinal Microstimulation Implants for Human Translation". Annals of Biomedical Engineering 45, n.º 3 (25 de agosto de 2016): 681–94. http://dx.doi.org/10.1007/s10439-016-1709-0.

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Holinski, B. J., K. A. Mazurek, D. G. Everaert, A. Toossi, A. M. Lucas-Osma, P. Troyk, R. Etienne-Cummings, R. B. Stein y V. K. Mushahwar. "Intraspinal microstimulation produces over-ground walking in anesthetized cats". Journal of Neural Engineering 13, n.º 5 (13 de septiembre de 2016): 056016. http://dx.doi.org/10.1088/1741-2560/13/5/056016.

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Rouhani, Ehsan y Abbas Erfanian. "Block-based robust control of stepping using intraspinal microstimulation". Journal of Neural Engineering 15, n.º 4 (13 de junio de 2018): 046026. http://dx.doi.org/10.1088/1741-2552/aac4b8.

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Saigal, R., C. Renzi y V. K. Mushahwar. "Intraspinal Microstimulation Generates Functional Movements After Spinal-Cord Injury". IEEE Transactions on Neural Systems and Rehabilitation Engineering 12, n.º 4 (diciembre de 2004): 430–40. http://dx.doi.org/10.1109/tnsre.2004.837754.

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Grahn, Peter J., Stephan J. Goerss, J. Luis Lujan, Grant W. Mallory, Bruce A. Kall, Aldo A. Mendez, James K. Trevathan, Joel P. Felmlee, Kevin E. Bennet y Kendall H. Lee. "MRI-Guided Stereotactic System for Delivery of Intraspinal Microstimulation". SPINE 41, n.º 13 (julio de 2016): E806—E813. http://dx.doi.org/10.1097/brs.0000000000001397.

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Tesis sobre el tema "Intraspinal Microstimulations"

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Luan, Song. "Integrated electronics for targeted intraspinal microstimulation". Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/18231.

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Intraspinal microstimulation (ISMS) is an emerging method that is applied to neuroprosthesis aimed at individuals with spinal cord injury. Compared to traditional spinal stimulation or peripheral nerve stimulation methods, ISMS can activate muscle groups in organised synergies and thus can provide finer control of the generated force with reduced muscle fatigue. As the spinal cord is the neural link between the central and peripheral nervous systems, it is convenient to use this in accessing neurons associated with limb movement within a small area. For example, the relevant length of the spinal cord controlling the lower limbs in humans is only 5 cm. However, this means that any implant surgery is limited to some extent, on the other hand, this means ISMS needs to use invasive electric neural stimulation (ENS) with microelectrodes to access the target motor neurons to achieve a higher spatial resolution. Similar to other implantable ENS systems, an ISMS system needs to be compact, safe and energy efficient (in addition to effectively provide the required therapy). Although existing implantable neural stimulators fulfil these basic requirements, there is still much room for improvement. Depending on whether the stimulus is current or voltage controlled, the stimulator can be good for either safety and controllability or energy efficiency. Since the trend in the semiconductor industry is to reduce power consumption in integrated circuits, a current controlled stimulator is usually preferable by experimental neuroscientists. However, there is a new trend to combine these two control modalities, to enjoy the benefits of both. Following this trend, this thesis starts by focusing on a third modality -- charge controlled stimulation, which delivers the stimulus in charge packets. This eliminates the voltage headroom required for relatively high output resistances in current controlled stimulators whilst preserving the controllability over the total charge delivered. Charge controlled stimulation is thus proposed for having the potential to be as energy efficient as voltage controlled stimulation and as safe as current controlled stimulator. A novel circuit for charge mode stimulation is described based on a charge metering approach that has been adopted from nuclear engineering. Experimental results demonstrate the feasibility of this approach and also identify the key challenges. This is then extended to a novel reconfigurable, multi-modal and multichannel stimulator circuit. This is the first integrated system to implement current, voltage and charge control stimulation within a reconfigurable channel architecture. This has been developed to investigate the effect of dynamic multipolar electrode reconfiguration with the aim of focusing or steering the stimulus. To this end, different stimulus delivery methods can be tested for multipolar spatial control. The concept of multipolar stimulation is then investigated from a theoretical standpoint. The ability to apply this in improving the spatial resolution in ISMS can be achieved by confining the stimulus spread (thus reducing destructive crosstalk). This method can also be used to shift the stimulus voltage field away from the delivering electrode so as to correct implant placement error during surgery. A theoretical computational model is developed to investigate the effect of dynamic multipolar electrode reconfiguration with the aim of focusing or steering the stimulus. It is intended, together with the developed multichannel stimulator, that this will be used in future to develop advanced multipolar strategies that can achieve spatial hyperacuity for ISMS, and more generally in ENS.
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Zimmerman, Jonas B. "Cortical control of intraspinal microstimulation to restore motor function after paralysis". Thesis, University of Newcastle Upon Tyne, 2012. http://hdl.handle.net/10443/1781.

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Spinal cord injury (SCI) is a devastating condition affecting the quality of life of many otherwise healthy patients. To date, no cure or therapy is known to restore functional movements of the arm and hand, and despite considerable effort, stem cell based therapies have not been proven effective. As an alternative, nerves or muscles below the injury could be stimulated electrically. While there have been successful demonstrations of restoration of functional movement using muscle stimulation both in humans and non-human primates, intraspinal microstimulation (ISMS) could bear benefits over peripheral stimulation. An extensive body of research on spinal stimulation has been accumulated – however, almost exclusively in non-primate species. Importantly, the primate motor system has evolved to be quite different from the frog's or the cat's – two commonly studied species –, reflecting and enabling changes in how primates use their hands. Because of these functional and anatomical differences, it is fair to assume that also spinal cord stimulation will have different effects in primates. This question – what are the movements elicited by ISMS in the macaque – will be addressed in chapters 2 and 3. Chronic intraspinal electrode implants so far have been difficult to realise. In chapter 4 we describe a novel use of floating microelectrode arrays (FMAs) as chronic implants in the spinal cord. Compared to implanted microwires or other arrays, these FMAs have the benefit of a high electrode density combined with different lengths of electrodes. We were able to maintain these arrays in the cord for months and could elicit movements at low thresholds throughout. If we could build a neural prosthesis stimulating the spinal cord, how would it be controlled? Remarkable progress has been recently achieved in the field of brain-machine interfaces (BMIs), for example enabling patients to control robotic arms with neural signals recorded from chronically implanted electrodes. Chapter 5 of this thesis examines an approach that combines ISMS with cortical control in a macaque model for upper limb paralysis for the first time and shows that there is a behavioural improvement. We have devised an experiment in which a monkey trained to perform a grasp-and-pull task receives a temporary cortically induced paralysis of the hand reducing task performance. At the same time, cortical recordings from a different area allow us to control ISMS at sites evoking hand movements – thus partially restoring function. Finally, in appendix A we describe a system we developed in order to introduce automated positive reinforcement training (aPRT) both at the breeding facility and in our animal houses. This system potentially reduces time spent on training animals, adds enrichment to the monkeys' home environment, and allows for suitability screening of monkeys for behavioural neuroscience experiments.
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shahdoostfard, shahabedin. "A MINIATURIZED BRAIN-MACHINE-SPINAL CORD INTERFACE (BMSI) FOR CLOSED-LOOP INTRASPINAL MICROSTIMULATION". Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1502108119503029.

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Moffitt, Michael Adam. "Functional Imaging of the Mammalian Spinal Cord". Case Western Reserve University School of Graduate Studies / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=case1081363883.

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Rodella, Andrea. "Analytical and numerical modelling of undulatory locomotion for limbless organisms in granular/viscous media". Doctoral thesis, Università degli studi di Trento, 2020. http://hdl.handle.net/11572/273235.

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Undulatory locomotion is a common and powerful strategy used in nature at different biological scales by a broad range of living organisms, from flagellated bacteria to prehistoric snakes, which have overcome the complexity of living in ”flowable” media. By taking inspiration from this evolution-induced strategy, we aim at modelling the locomotion in a granular and viscous environment with the objective to provide more insights for designing robots for soil-like media exploration. Moreover, in contrast to common types of movement, the granular locomotion is still not well understood and is an open and challenging field. We approached this phenomenon with several tools: (i.) numerically, via coupling the Finite Element Method (FEM) with the Discrete Element Method (DEM) using ABAQUS; (ii.) analytically, by employing the Lagrangian formalism to derive the equations of motion of a discrete and continuous system subject to non-conservative forces, and (iii.) experimentally, by creating an ad-hoc set up in order to observe the migration of microfibres used for the treatment of spinal cord injuries. The computational attempts to model the motion in a granular medium involved the simulation of the dynamics of an elastic beam (FEM) surrounded by rigid spherical particles (DEM). A propulsion mechanism was introduced by sinusoidally forcing the beam’s tip normally to the longitudinal axis, while the performance of the locomotion was evaluated by means of a parametric study. Depending on the parameters of the external excitation, after a transient phase, the slender body reached a steady-state with a constant translational velocity. In order to gain physical insights, we studied a simplified version of the previous continuous beam by introducing a discrete multi-bar system. The dynamics of the latter was analytically derived, by taking into account the forces exchanged between the locomotor and the environment, according to the Resistive Force Theory. By numerically solving the equations of motion and evaluating the input energy and dissipations, we were able to define the efficiency and thus provide an effective tool to optimise the locomotion. It is worth mentioning that the two approaches, despite the different physical hypothesis, show a qualitatively and quantitatively good accordance. The numerical and analytical models previously analysed have shown promising results for the interpretation of "ad-hoc" experiments that demonstrate the migration of a microfibre embedded in a spinal cord-like matrix. This migration needs to be avoided, once the regenerative microfibre is implanted in the lesioned spinal cord, for the sake of the patients health.
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Bamford, Jeremy Andrew. "Motor unit recruitment by intraspinal microstimulation and long-term neuromuscular adaptations". Phd thesis, 2009. http://hdl.handle.net/10048/656.

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Thesis (Ph.D.)--University of Alberta, 2009.
A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Doctor of Philosophy, Centre for Neuroscience. Title from pdf file main screen (viewed on October 11, 2009). Includes bibliographical references.
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Christian, Breanne. "Developing experimental methods for identifying the sites of action of intraspinal microstimulation". Master's thesis, 2011. http://hdl.handle.net/10048/1938.

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Intraspinal microstimulation (ISMS) is a novel electrical stimulation approach to restore standing and ambulation in people with spinal cord injury. The technique entails inserting an array of microwires into the lumbosacral enlargement of the spinal cord to activate neuronal networks that control locomotion. Additionally, ISMS can be utilized to investigate the organization of these networks. In the present study, experimental methodology was developed to map the distribution of ISMS-activated neurons using immunohistochemistry to label c-Fos, an activity-dependent marker. The influence on c-Fos expression of the following conditions was studied: decerebration, laminectomy, microwire implantation, and ISMS. Data revealed that microwire implantation and decerebration minimally influenced c-Fos, while a laminectomy substantially increased c-Fos expression. Furthermore, results indicated that it is vital to monitor stimulation and adjust stimulus amplitude throughout the duration of stimulation. Using these data, a protocol was established that would aid in mapping the ISMS activated neuronal networks.
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Barthélemy, Dorothy. "Stimulation électrique de la moelle épinière lombaire pour déclencher la marche chez le chat spinal". Thèse, 2006. http://hdl.handle.net/1866/15691.

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Capítulos de libros sobre el tema "Intraspinal Microstimulations"

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"Intraspinal Microstimulation". En Encyclopedia of Computational Neuroscience, 1448. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-6675-8_100281.

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Giszter, Simon, Warren Grill, Michel Lemay, Vivian Mushahwar y Arthur Prochazka. "Intraspinal Microstimulation". En Neural Prostheses for Restoration of Sensory and Motor Function. CRC Press, 2000. http://dx.doi.org/10.1201/9781420039054.ch4.

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Bamford, Jeremy A. y Vivian K. Mushahwar. "Intraspinal microstimulation for the recovery of function following spinal cord injury". En Brain Machine Interfaces: Implications for Science, Clinical Practice and Society, 227–39. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-444-53815-4.00004-2.

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Actas de conferencias sobre el tema "Intraspinal Microstimulations"

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Troyk, P. R., V. K. Mushahwar, R. B. Stein, Sungjae Suh, D. Everaert, B. Holinski, Zhe Hu, G. DeMichele, D. Kerns y K. Kayvani. "An implantable neural stimulator for Intraspinal MicroStimulation". En 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6346077.

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Tao, Chunling, Xiaoyan Shen, Lei Ma, Jiahuan Shen, Zhiling Li, Zhigong Wang y Xiaoying Lu. "Comparative Study of Intraspinal Microstimulation and Epidural Spinal Cord Stimulation". En 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019. http://dx.doi.org/10.1109/embc.2019.8857696.

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Roshani, Amir y Abbas Erfanian. "Fuzzy logic control of ankle movement using multi-electrode intraspinal microstimulation". En 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2013. http://dx.doi.org/10.1109/embc.2013.6610830.

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Rouhani, E. y A. Erfanian. "Control of intraspinal microstimulation using an adaptive terminal-based neuro-sliding mode control". En 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2015. http://dx.doi.org/10.1109/ner.2015.7146667.

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Asadi, Ali-Reza y Abbas Erfanian. "Control of rhythmic locomotor-like activity through intraspinal microstimulation with high frequency resolution". En 5th International IEEE/EMBS Conference on Neural Engineering (NER 2011). IEEE, 2011. http://dx.doi.org/10.1109/ner.2011.5910532.

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Shahdoost, Shahab, Shawn Frost, David Guggenmos, Jordan Borrell, Caleb Dunham, Scott Barbay, Randolph Nudo y Pedram Mohseni. "A miniaturized brain-machine-spinal cord interface (BMSI) for closed-loop intraspinal microstimulation". En 2016 IEEE Biomedical Circuits and Systems Conference (BioCAS). IEEE, 2016. http://dx.doi.org/10.1109/biocas.2016.7833807.

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Holinski, B. J., K. A. Mazurek, D. G. Everaert, R. B. Stein y V. K. Mushahwar. "Restoring stepping after spinal cord injury using intraspinal microstimulation and novel control strategies". En 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6091435.

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Tao, Chunling, Xiaoyan Shen, Lei Ma, Zhiling Li y Jiahuan Shen. "Three-dimensional Map of Lumbar Spinal Cord Motor Function for Intraspinal Microstimulation in Rats". En 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society. IEEE, 2020. http://dx.doi.org/10.1109/embc44109.2020.9175963.

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Shahdoost, Shahab, Pedram Mohseni, Shawn Frost y Randolph Nudo. "A multichannel corticospinal interface IC for intracortical spike recording and distinct muscle pattern activation via intraspinal microstimulation". En 2014 IEEE 57th International Midwest Symposium on Circuits and Systems (MWSCAS). IEEE, 2014. http://dx.doi.org/10.1109/mwscas.2014.6908414.

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Shahdoost, Shahab, Shawn Frost, Caleb Dunham, Stacey DeJong, Scott Barbay, Randolph Nudo y Pedram Mohseni. "Cortical control of intraspinal microstimulation: Toward a new approach for restoration of function after spinal cord injury". En 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7318817.

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