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1

Jobdal, Kell. "THE LEWIS BLOOD GROUPS IN CHILDREN." Acta Pathologica Microbiologica Scandinavica 39, no. 6 (August 14, 2009): 399–406. http://dx.doi.org/10.1111/j.1699-0463.1956.tb05068.x.

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2

Tertti, R., H. J�rvinen, R. Lahesmaa, U. Yli-Kerttula, and A. Toivanen. "ABO and Lewis blood groups in reactive arthritis." Rheumatology International 12, no. 3 (July 1992): 103–5. http://dx.doi.org/10.1007/bf00290263.

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3

Mukhopadhyay, Chaitali, and C. Allen Bush. "Molecular dynamics simulation of Lewis blood groups and related oligosaccharides." Biopolymers 31, no. 14 (December 1991): 1737–46. http://dx.doi.org/10.1002/bip.360311408.

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4

Santos, Joao, Luiz Leite, Horacio Soares, Elisangela Santos, and Danilo Ramos. "The influence of Lewis, Duffy and Kidd blood groups on renal allograft rejection: Review." International Journal of Medical Reviews and Case Reports 3, Reports in Clinical Medicine (2019): 1. http://dx.doi.org/10.5455/ijmrcr.lewis-duffy-kidd-blood-groups.

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5

Mohr., Jan. "ESTIMATION OF LINKAGE BETWEEN THE LUTHERAN AND THE LEWIS BLOOD GROUPS." Acta Pathologica Microbiologica Scandinavica 29, no. 3 (August 17, 2009): 339–44. http://dx.doi.org/10.1111/j.1699-0463.1951.tb00136.x.

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6

Henry, Stephen M., and D. Graeme Woodfiel. "A possible relationship between colorectal carcinoma and ABO/Lewis blood groups." Immunohematology 9, no. 4 (2020): 101–4. http://dx.doi.org/10.21307/immunohematology-2019-968.

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7

Anstee, David J. "The relationship between blood groups and disease." Blood 115, no. 23 (June 10, 2010): 4635–43. http://dx.doi.org/10.1182/blood-2010-01-261859.

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Abstract The relative contribution of founder effects and natural selection to the observed distribution of human blood groups has been debated since blood group frequencies were shown to differ between populations almost a century ago. Advances in our understanding of the migration patterns of early humans from Africa to populate the rest of the world obtained through the use of Y chromosome and mtDNA markers do much to inform this debate. There are clear examples of protection against infectious diseases from inheritance of polymorphisms in genes encoding and regulating the expression of ABH
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8

Mattos, Luiz Carlos de, Juliana Rodrigues Cintra, Fábio Eduardo Sanches, Rita de Cássia Martins Alves da Silva, Milton Artur Ruiz, and Haroldo Wilson Moreira. "ABO, Lewis, secretor and non-secretor phenotypes in patients infected or uninfected by the Helicobacter pylori bacillus." Sao Paulo Medical Journal 120, no. 2 (March 2002): 55–58. http://dx.doi.org/10.1590/s1516-31802002000200006.

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CONTEXT: Epidemiological studies have demonstrated higher frequencies of the O blood group and the non-secretor phenotype of ABH antigens among patients suffering from peptic ulcers. Since Helicobacter pylori has been established as the main etiological factor in this disease, controversies about the associations of the ABO and Lewis blood group phenotypes and secretor and non-secretor phenotypes in relation to susceptibility towards infection by this bacillus have been presented. OBJECTIVE: To verify the frequencies of ABO, Lewis blood group phenotypes, secretor and non-secretor phenotypes in
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9

Kushwaha, K. P. S., and S. M. S. Chahal. "Distribution of the Rhesus, P, Kell, Duffy and Lewis Blood Groups in Haryana." Journal of Human Ecology 8, no. 6 (November 1997): 467–70. http://dx.doi.org/10.1080/09709274.1997.11907317.

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10

Ferreira, José A., M. Rosário M. Domingues, Ana Reis, Mario A. Monteiro, and Manuel A. Coimbra. "Differentiation of isomeric Lewis blood groups by positive ion electrospray tandem mass spectrometry." Analytical Biochemistry 397, no. 2 (February 2010): 186–96. http://dx.doi.org/10.1016/j.ab.2009.10.034.

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11

Monteiro, Mario A., Frank St Michael, David A. Rasko, Diane E. Taylor, J. Wayne Conlan, Ken H. Chan, Susan M. Logan, Ben J. Appelmelk, and Malcolm B. Perry. "Helicobacter pylorifrom asymptomatic hosts expressing heptoglycan but lacking Lewis O-chains: Lewis blood-group O-chains may play a role inHelicobacter pyloriinduced pathology." Biochemistry and Cell Biology 79, no. 4 (August 1, 2001): 449–59. http://dx.doi.org/10.1139/o01-035.

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Helicobacter pylori is a widespread Gram-negative bacterium responsible for the onset of various gastric pathologies and cancers in humans. A familiar trait of H. pylori is the production of cell-surface lipopolysaccharides (LPSs; O-chain [Formula: see text] core [Formula: see text] lipid A) with O-chain structures analogous to some mammalian histo-blood-group antigens, those being the Lewis determinants (Lea, Leb, Lex, sialyl Lex, Ley) and blood groups A and linear B. Some of these LPS antigens have been implicated as autoimmune, adhesion, and colonization components of H. pylori pathogenic m
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12

Dieckmann, K. P., R. Klän, and S. Bünte. "HLA Antigens, Lewis Antigens, and Blood Groups in Patients with Testicular Germ-Cell Tumors." Oncology 50, no. 4 (1993): 252–58. http://dx.doi.org/10.1159/000227190.

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13

Huang, Pengwei, Tibor Farkas, Weiming Zhong, Ming Tan, Scott Thornton, Ardythe L. Morrow, and Xi Jiang. "Norovirus and Histo-Blood Group Antigens: Demonstration of a Wide Spectrum of Strain Specificities and Classification of Two Major Binding Groups among Multiple Binding Patterns." Journal of Virology 79, no. 11 (June 1, 2005): 6714–22. http://dx.doi.org/10.1128/jvi.79.11.6714-6722.2005.

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ABSTRACT Noroviruses, an important cause of acute gastroenteritis, have been found to recognize human histo-blood group antigens (HBGAs) as receptors. Four strain-specific binding patterns to HBGAs have been described in our previous report. In this study, we have extended the binding patterns to seven based on 14 noroviruses examined. The oligosaccharide-based assays revealed additional epitopes that were not detected by the saliva-based assays. The seven patterns have been classified into two groups according to their interactions with three major epitopes (A/B, H, and Lewis) of human HBGAs:
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14

Abdul, Fatima Rammadan, and Khedhir H. Ali. "Contribution of Lewis blood groups molecules in biofilm formation of Pseudomonas aeruginosa isolated from atopic dermatitis patients." Al-Mustansiriyah Journal of Science 29, no. 2 (November 17, 2018): 69. http://dx.doi.org/10.23851/mjs.v29i2.302.

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Abstract 
 Biofilm formation is a mechanism for bacterial community defense against insults including antibiotics .In this report we evaluated the potency of Pseudomonas aeruginosa(P. aeruginosa) isolates from atopic dermatitis patients skin as well as stool to colonize different Lewis types saliva , manifested by biofilm formation .
 The bacteria were cultured on tryptose soy broth .96-well polystyrene plate were used .Coating with heat inactivated Le (a), (b) and (c)saliva was performed. Biofilm intensity was measured using crystal violet stained films compared to non –saliva coate
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15

Falcão, L. Menezes, M. João Marta, Alda P. Silva, M. Bicho, J. Braz Nogueira, and P. Van Zwieten. "MN and Lewis Blood groups in the failing heart in hypertensive patients with dilated cardiomyopathy." European Journal of Heart Failure 2 (June 2000): 52–53. http://dx.doi.org/10.1016/s1388-9842(00)80184-1.

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16

CLARK, P., and I. A. GREER. "The influence of maternal Lewis, Secretor and ABO(H) blood groups on fetal growth restriction." Journal of Thrombosis and Haemostasis 9, no. 12 (December 2011): 2411–15. http://dx.doi.org/10.1111/j.1538-7836.2011.04515.x.

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17

Falcão, L. Menezes, Ma João Marta, M. Bicho, and J. Braz Nogueira. "MN AND LEWIS BLOOD GROUPS IN THE FAILING HEART IN HYPERTENSIVE PATIENTS WITH DILATED CARDIOMYOPATHY." Journal of Hypertension 18 (June 2000): S113. http://dx.doi.org/10.1097/00004872-200006001-00385.

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18

Keramati, MohammadReza, SeyedRasoul Zakavi, MohammadHadi Sadeghian, Hedieh Akbari, and Kamran Aryana. "Association of Helicobacter pylori infection with the Lewis and ABO blood groups in dyspeptic patients." Nigerian Medical Journal 54, no. 3 (2013): 196. http://dx.doi.org/10.4103/0300-1652.114583.

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19

CLARK, P., D. J. MEIKLEJOHN, A. O'SULLIVAN, M. A. VICKERS, and M. GREAVES. "The relationships of ABO, Lewis and Secretor blood groups with cerebral ischaemia of arterial origin." Journal of Thrombosis and Haemostasis 3, no. 9 (September 2005): 2105–8. http://dx.doi.org/10.1111/j.1538-7836.2005.01535.x.

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20

Wang, Wen-Ping, Long-Qi Chen, Han-Lu Zhang, Yu-Shang Yang, Song-Lin He, and Yun Wang. "PS01.224: MODIFIED INTRATHORACIC ESOPHAGOGASTROSTOMY AT MINIMALLY INVASIVE ROBOT-ASSISTED IVOR-LEWIS ESOPHAGECTOMY FOR CANCER." Diseases of the Esophagus 31, Supplement_1 (September 1, 2018): 113–14. http://dx.doi.org/10.1093/dote/doy089.ps01.224.

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Abstract Background The intrathoracic esophagogastrostomy played important role in minimally invasive Ivor-Lewis esophagectomy for cancer. The methods of intrathoracic esophagogastric anastomosis at robot-assisted Ivor-Lewis esophagectomy mostly included hand-sewn, and circular stapler (anvil placement via OrVil system or transthoracically), which were still technically challenging. In this study, we modified the techniques of intrathoracic esophagogastric anastomosis at robot-assisted Ivor-Lewis esophagectomy for cancer, in order to seek to simplify this complicated intrathoracic procedure. T
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21

Ho, Beng-Chuan, Lai-Ming Chew, Eu-Hian Yap, and Mulkit Singh. "Infections of forest rat filaria, Breinlia booliati, in neonate and juvenile laboratory white rats." Journal of Helminthology 61, no. 3 (September 1987): 203–12. http://dx.doi.org/10.1017/s0022149x00010026.

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ABSTRACTThe kinetics of Breinlia booliati infection in 3 inbred rat strains (Lewis, Wistar and Sprague Dawley) were investigated. One group of rats was infected as neonates (less than 24 hours of age) with third-stage larvae of B. booliati and the other group was infected as juveniles (4 weeks of age). The results showed that infection in the neonates were significantly different from the infection in the juveniles. The 60 rats infected as neonates, when necropsied between 8 to 10 months postinfection, yielded adult worms. The 2 neonatal infection groups of Lewis and Wistar strains showed high
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22

Spohr, Ulrike, Naohiko Morishima, Ole Hindsgaul, and Raymond U. Lemieux. "Molecular recognition. IV. The binding of the Lewis b human blood group determinant by a hybridoma monoclonal antibody." Canadian Journal of Chemistry 63, no. 10 (October 1, 1985): 2659–63. http://dx.doi.org/10.1139/v85-441.

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A commercial hybridoma monoclonal anti-Lewis b antibody appears to accept the Lewis b human blood group determinant (αLFuc(1→2)βDGal(1 → 3)[αLFuc(1 → 4)]βDGlcNAc--) by involving OH-3 of the βDGal unit and OH-2 of the αLFuc(1 → 2) unit in a key polar interaction at the periphery of a large wedge-shaped lipophilic surface that extends about the tetrasaccharide and essentially leaves 5 of the 8 other hydroxyl groups in contact with the aqueous phase. It is proposed that the three remaining hydroxyl groups, namely, OH-4of the βDGal unit, OH-3 of the αLFuc(1 → 4) unit, and OH-4 of the αLFuc(1 → 2)
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23

Yamaleyeva, Liliya M., Karl D. Pendergrass, Nancy T. Pirro, Patricia E. Gallagher, Leanne Groban, and Mark C. Chappell. "Ovariectomy is protective against renal injury in the high-salt-fed older mRen2.Lewis rat." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 4 (October 2007): H2064—H2071. http://dx.doi.org/10.1152/ajpheart.00427.2007.

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Studies in experimental animals and younger women suggest a protective role for estrogen; however, clinical trials may not substantiate this effect in older females. Therefore, the present study assessed the outcome of ovariectomy in older mRen2.Lewis rats subjected to a high-salt diet for 4 wk. Intact or ovariectomized (OVX, 15 wk of age) mRen2.Lewis rats were aged to 60 wk and then placed on a high-salt (HS, 8% sodium chloride) diet for 4 wk. Systolic blood pressures were similar between groups [OVX 169 ± 6 vs. Intact 182 ± 7 mmHg; P = 0.22] after the 4-wk diet; however, proteinuria [OVX 0.8
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24

Pendergrass, Karl D., Nancy T. Pirro, Brian M. Westwood, Carlos M. Ferrario, K. Bridget Brosnihan, and Mark C. Chappell. "Sex differences in circulating and renal angiotensins of hypertensive mRen().Lewis but not normotensive Lewis rats." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 1 (July 2008): H10—H20. http://dx.doi.org/10.1152/ajpheart.01277.2007.

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Sex differences in blood pressure are evident in experimental models and human subjects, yet the mechanisms underlying this disparity remain equivocal. The current study sought to define the extent of male-female differences in the circulating and tissue renin-angiotensin aldosterone systems (RAASs) of congenic mRen( 2 ).Lewis and control Lewis rats. Male congenics exhibited higher systolic blood pressure than females [200 ± 4 vs. 146 ± 7 mmHg, P < 0.01] or Lewis males and females [113 ± 2 vs. 112 ± 2 mmHg, P > 0.05]. Plasma ANG II levels were twofold higher in male congenics [47 ± 3 vs.
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25

Park, Jong-Lim, Taewoon Kim, and Baek-Kyu Kim. "Suitability of denervated muscle flaps as recipient sites for pancreatic islet cell transplantation." Archives of Plastic Surgery 48, no. 1 (January 15, 2021): 133–43. http://dx.doi.org/10.5999/aps.2020.01865.

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Background Extensive research has been conducted on islet transplantation as a possible cure for diabetes. Islet transplantation in the liver via the portal vein has shown remarkable results, but numerous other recipient sites are currently being investigated. We aimed to show the effectiveness of using a muscle flap as a recipient site for islet transplantation.Methods Islet cells were harvested from 12 isogenic Lewis rats, and then diabetes was induced in another 12 isogenic Lewis rats by streptozotocin injection. In six rats, 3,000 islets were transplanted into gastrocnemius muscle flaps, a
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26

Ow, Connie P. C., Amany Abdelkader, Lucinda M. Hilliard, Jacqueline K. Phillips, and Roger G. Evans. "Determinants of renal tissue hypoxia in a rat model of polycystic kidney disease." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 307, no. 10 (November 15, 2014): R1207—R1215. http://dx.doi.org/10.1152/ajpregu.00202.2014.

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Renal tissue oxygen tension (Po2) and its determinants have not been quantified in polycystic kidney disease (PKD). Therefore, we measured kidney tissue Po2 in the Lewis rat model of PKD (LPK) and in Lewis control rats. We also determined the relative contributions of altered renal oxygen delivery and consumption to renal tissue hypoxia in LPK rats. Po2 of the superficial cortex of 11- to 13-wk-old LPK rats, measured by Clark electrode with the rat under anesthesia, was higher within the cysts (32.8 ± 4.0 mmHg) than the superficial cortical parenchyma (18.3 ± 3.5 mmHg). Po2 in the superficial
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27

Kuemmel, Andreas, Kristjan Single, Fernando Bittinger, Andrea Faldum, Lars Henning Schmidt, Martin Sebastian, Christian Taube, Roland Buhl, and Rainer Wiewrodt. "The Prognostic Impact of Blood Group-Related Antigen Lewis Y and the ABH Blood Groups in Resected Non-Small Cell Lung Cancer." Tumor Biology 28, no. 6 (2007): 340–49. http://dx.doi.org/10.1159/000124298.

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28

Quek, Ko Jin, Omar Z. Ameer, and Jacqueline K. Phillips. "Amlodipine Improves Vessel Function and Remodeling in the Lewis Polycystic Kidney Rat Mesenteric Artery." American Journal of Hypertension 33, no. 7 (March 26, 2020): 634–43. http://dx.doi.org/10.1093/ajh/hpaa054.

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Abstract BACKGROUND Hypertension is a common comorbidity associated with chronic kidney disease (CKD). Treatment in these patients often involves L-type Ca2+ channel (LTCC) blockers. The effect of chronic LTCC-blockade treatment on resistance vasculature was investigated in a genetic hypertensive rat model of CKD, the Lewis Polycystic Kidney (LPK) rat. METHODS Mixed-sex LPK and Lewis control rats (total n = 38) were allocated to treated (amlodipine 20 mg/kg/day p.o. from 4 to 18 weeks) and vehicle groups. Following systolic blood pressure and renal function assessment, animals were euthanized
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29

Orstavik, KH, L. Kornstad, H. Reisner, and K. Berg. "Possible effect of secretor locus on plasma concentration of factor VIII and von Willebrand factor." Blood 73, no. 4 (March 1, 1989): 990–93. http://dx.doi.org/10.1182/blood.v73.4.990.990.

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Abstract A significant fraction (30%) of the genetically determined variance in plasma concentration of the von Willebrand factor antigen (vWf:Ag) has been shown to be related to ABH determinants. Individuals with blood group O, who have the highest amounts of blood group H substance, have the lowest concentration of vWf:Ag. The Lewis substances, Le(a) and Le(b), are biochemically closely related to the ABH substances as both can be produced from the same precursor substance. We studied the effect of the presence of the Lewis antigens on the plasma concentration of vWf:Ag and factor VIII antig
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30

Orstavik, KH, L. Kornstad, H. Reisner, and K. Berg. "Possible effect of secretor locus on plasma concentration of factor VIII and von Willebrand factor." Blood 73, no. 4 (March 1, 1989): 990–93. http://dx.doi.org/10.1182/blood.v73.4.990.bloodjournal734990.

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A significant fraction (30%) of the genetically determined variance in plasma concentration of the von Willebrand factor antigen (vWf:Ag) has been shown to be related to ABH determinants. Individuals with blood group O, who have the highest amounts of blood group H substance, have the lowest concentration of vWf:Ag. The Lewis substances, Le(a) and Le(b), are biochemically closely related to the ABH substances as both can be produced from the same precursor substance. We studied the effect of the presence of the Lewis antigens on the plasma concentration of vWf:Ag and factor VIII antigen (VIII:
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31

Lee, Jong Y., and Silvia H. Azar. "Effects of Perinatal Protein-Nacl Diets on Offspring's Blood Pressure and Renal Function in Lewis Rats." Open Hypertension Journal 5, no. 1 (April 19, 2013): 1–11. http://dx.doi.org/10.2174/1876526201305010001.

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Perinatal diets may affect the cardiovascular-renal functions of offspring. To understand effects of maternal diet on the renal function and blood pressure (BP) of offspring, protein (10% low, LP; 23% normal, NP) and/or NaCl (4% high salt, HS; 0.6% normal, NS) diets were started at pre-pregnancy through pups' weaning to either a 4% high NaCl (hs) or 0.6% NaCl (ns) diet. Telemetered BP data was analyzed by methods of linear least square rhythmometry. Systolic BPs (circadian mean ±SE mm Hg) were: NPNSns, 131±2; NPNShs, 137±2; NPHSns, 137±0.2; NPHShs, 134±3; LPNSns, 138±1; LPNShs, 138±0.6; LPHSns
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32

Spohr, Ulrike, Ole Hindsgaul, and Raymond U. Lemieux. "Molecular recognition. II. The binding of the Lewis b and Y human blood group determinants by the lectin IV of Griffoniasimplicifolia." Canadian Journal of Chemistry 63, no. 10 (October 1, 1985): 2644–52. http://dx.doi.org/10.1139/v85-439.

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Using a radioimmunoassay to measure the relative potencies as inhibitors of a wide number of chemically modified structures related to the Lewis b human blood group determinant, it was found that derivatives of the Lewis b (αLFuc(1→2)βDGal(1→3)[αLFuc(1→4)]βDGlcNAc) and the Y (αLFuc(1→2)PDGal(1→4)[αLFuc(1→3)]βDGlcNAc) determinants are complexed by the lectin IV of Griffoniasimplicifolia through the recognition of a topographical feature that is common to both the tetrasaccharides. This surface provides a nonpolar region formed by the two methyl groups of the fucose units and extends along the C
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33

Clark, Peter, and Olivia Wu. "P15. The influence of maternal Lewis, Secretor and ABO(H) blood groups on pre-eclampsia and fetal growth restriction." Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health 1, no. 3-4 (July 2011): 280. http://dx.doi.org/10.1016/j.preghy.2011.08.076.

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34

Chandramohan, Servarayan, Visvarath Varadharajan, Madeshwaran Chinnathambi, Kanagavel Manickavasagam, Abishai Jebaraj, and Apsara Chandramohan. "PS01.158: WHAT IS THE IDEAL RECONSTRUCTIVE TECHNIQUE FOR TYPE 2 GEJ TUMOURS—ESOPHAGOGASTROSTOMY OR ESOPHAGOJEJUNOSTOMY." Diseases of the Esophagus 31, Supplement_1 (September 1, 2018): 94. http://dx.doi.org/10.1093/dote/doy089.ps01.158.

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Abstract Background In the management of OG junction tumors the border issue arises in type 2 cancers. It can be managed with various options like esophago gastrectomy (Ivor Lewis), transabdominal extended transhiatal gastrectomy or total esophago gastrectomy depends upon the extent strectomy of the tumor above and below. After resection the reconstruction can be either with stomach or jejunum or colon. However the functional result after either of these procedures varies. The aim of this study is to know the functional outcome of different reconstruction methods after esophagogastrectomy for
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35

Abdul, Fatima Rammadan. "Biofilm formation by Staphylococcus aureus isolation from atopic dermatitis patients on defined Lewis types saliva." Journal of University of Babylon 26, no. 5 (March 12, 2018): 233–40. http://dx.doi.org/10.29196/jub.v26i5.921.

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Bacteria adherence and biofilm formation vary depending on the strain of microorganism as well as the substrate.Here, we evaluated the ability of different isolates of Staphylococcus aureus (S. aureus), isolated. from atopic dermatitis patients skin and stool to form a biofilm on different Lewis types saliva, including Le (a) , (b) ,(c) and Le a+b+ saliva. S. aureus isolates were cultured on tryptose soy broth.The bacteria were used to form a biofilm on 96- well flat bottom Microtitration plate that was coated with the respective, optimally diluted, processed saliva of Lewis blood groups (a),(
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36

Abdul, Fatima Rammadan. "Biofilm formation by Staphylococcus aureus Isolation from atopic Dermatitis Patients on Defined Lewis Types saliva." JOURNAL OF UNIVERSITY OF BABYLON for Pure and Applied Sciences 26, no. 5 (March 12, 2018): 233–40. http://dx.doi.org/10.29196/jubpas.v26i5.921.

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Bacteria adherence and biofilm formation vary depending on the strain of microorganism as well as the substrate.Here, we evaluated the ability of different isolates of Staphylococcus aureus (S. aureus), isolated. from atopic dermatitis patients skin and stool to form a biofilm on different Lewis types saliva, including Le (a) , (b) ,(c) and Le a+b+ saliva. S. aureus isolates were cultured on tryptose soy broth.The bacteria were used to form a biofilm on 96- well flat bottom Microtitration plate that was coated with the respective, optimally diluted, processed saliva of Lewis blood groups (a),(
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37

Cohen, Jonathan A., Sarah H. Lindsey, Nancy T. Pirro, K. Bridget Brosnihan, Patricia E. Gallagher, and Mark C. Chappell. "Influence of estrogen depletion and salt loading on renal angiotensinogen expression in the mRen(2).Lewis strain." American Journal of Physiology-Renal Physiology 299, no. 1 (July 2010): F35—F42. http://dx.doi.org/10.1152/ajprenal.00138.2010.

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The mRen(2).Lewis (mRen2) strain is an ANG II-dependent model of hypertension expressing marked sex differences in blood pressure and tissue injury that also exhibits estrogen and salt sensitivity. Because estrogen and salt influence angiotensinogen (AGT), circulating and renal expression of the protein were assessed in the mRen2 using a sensitive and specific ELISA. Hemizygous female and male mRen2 were placed on normal (1% NaCl, NS)- or high (8% NaCl, HS)-salt diets from 5 to 15 wk of age while a separate NS cohort was ovariectomized (OVX). The OVX mRen2 exhibited higher blood pressure (184
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38

Zhu, Yanfei, and Jing Zhou. "Increased NPC1L1 and serum cholesterol in a chronic rejection rat." Clinical & Investigative Medicine 34, no. 3 (June 1, 2011): 172. http://dx.doi.org/10.25011/cim.v34i3.15190.

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Purpose: To measure serum cholesterol and triglyceride levels and NPC1L1 mRNA and protein as an index of cholesterol absorption during the development of chronic rejection (CR) in a rat model of intestinal transplantation. Methods: Rats were randomly divided into two groups: Group 1 (n=20) underwent syngenic Lewis-to-Lewis transplantation and Group 2 (n=20) underwent allogenic F344-to-Lewis transplantation as well as treatment with FK506. Blood samples and intestinal tissue were procured on the 190th day after operation. Histological changes were analyzed and the semiquantitative scores of his
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39

Manthorpe, R., L. Staub Nielsen, S. Hagen Petersen, and J. U. Prause. "Lewis Blood Type Frequency in Patients with Primary Sjögren's Syndrome:A Prospective Study Including Analyses for A1A2BO, Secretor, MNSs, P, Duffy, Kell, Lutheran and Rhesus Blood Groups." Scandinavian Journal of Rheumatology 14, no. 2 (January 1985): 159–62. http://dx.doi.org/10.3109/03009748509165497.

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40

Rolff, Hans C., Rikard B. Ambrus, Mohammed Belmouhand, Michael P. Achiam, Marianne Wegmann, Mette Siemsen, Steen C. Kofoed, and Lars B. Svendsen. "Robot-Assisted Hybrid Esophagectomy Is Associated with a Shorter Length of Stay Compared to Conventional Transthoracic Esophagectomy: A Retrospective Study." Minimally Invasive Surgery 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/6907896.

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Aim. To compare the peri- and postoperative data between a hybrid minimally invasive esophagectomy (HMIE) and the conventional Ivor Lewis esophagectomy. Methods. Retrospective comparison of perioperative characteristics, postoperative complications, and survival between HMIE and Ivor Lewis esophagectomy. Results. 216 patients were included, with 160 procedures performed with the conventional and 56 with the HMIE approach. Lower perioperative blood loss was found in the HMIE group (600 ml versus 200 ml, p<0.001). Also, a higher median number of lymph nodes were harvested in the HMIE group (m
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41

Kaneko, Mika, Shoko Nishihara, Naoko Shinya, Takashi Kudo, Hiroko Iwasaki, Taiko Seno, Yasuto Okubo, and Hisashi Narimatsu. "Wide Variety of Point Mutations in the H Gene of Bombay and Para-Bombay Individuals That Inactivate H Enzyme." Blood 90, no. 2 (July 15, 1997): 839–49. http://dx.doi.org/10.1182/blood.v90.2.839.

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Abstract The H genes, encoding an α1,2fucosyltransferase, which defines blood groups with the H structure, of four Bombay and 13 para-Bombay Japanese individuals were analyzed for mutations. Four Bombay individuals were homologous for the same null H allele, which is inactivated by a single nonsense mutation at position 695 from G to A (G695A), resulting in termination of H gene translation. The allele inactivated by the G695A was designated h1. The other 13 para-Bombay individuals possessed a trace amount of H antigens on erythrocytes regardless of their secretor status. Sequence analysis of
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42

Kaneko, Mika, Shoko Nishihara, Naoko Shinya, Takashi Kudo, Hiroko Iwasaki, Taiko Seno, Yasuto Okubo, and Hisashi Narimatsu. "Wide Variety of Point Mutations in the H Gene of Bombay and Para-Bombay Individuals That Inactivate H Enzyme." Blood 90, no. 2 (July 15, 1997): 839–49. http://dx.doi.org/10.1182/blood.v90.2.839.839_839_849.

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The H genes, encoding an α1,2fucosyltransferase, which defines blood groups with the H structure, of four Bombay and 13 para-Bombay Japanese individuals were analyzed for mutations. Four Bombay individuals were homologous for the same null H allele, which is inactivated by a single nonsense mutation at position 695 from G to A (G695A), resulting in termination of H gene translation. The allele inactivated by the G695A was designated h1. The other 13 para-Bombay individuals possessed a trace amount of H antigens on erythrocytes regardless of their secretor status. Sequence analysis of their H g
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43

Thurl, Stephan, Manfred Munzert, Jobst Henker, Günther Boehm, Beate Müller-Werner, Jürgen Jelinek, and Bernd Stahl. "Variation of human milk oligosaccharides in relation to milk groups and lactational periods." British Journal of Nutrition 104, no. 9 (June 4, 2010): 1261–71. http://dx.doi.org/10.1017/s0007114510002072.

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Human milk oligosaccharides, representing the third largest fraction of human milk, have been assigned important protective functions for newborns acting as bifidogenic substrates or as inhibitory agents towards pathogens. Using high-pH anion-exchange chromatography and an enzyme test kit, twenty oligosaccharides and lactose were determined in milk samples of German women from days 3 to 90 postpartum. Twenty-two secretor mothers with Lewis blood group Le(a − b+) synthesised all twenty oligosaccharides, and could be assigned to milk group 1. Five non-secretor mothers (Le(a+b − )) produced all o
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44

Pride, David T., Richard J. Meinersmann, and Martin J. Blaser. "Allelic Variation within Helicobacter pylori babA and babB." Infection and Immunity 69, no. 2 (February 1, 2001): 1160–71. http://dx.doi.org/10.1128/iai.69.2.1160-1171.2001.

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ABSTRACT Helicobacter pylori strains show both geographic and disease-associated allelic variation. We investigated the diversity present in two genes, babA and babB, which are members of a paralogous family of outer membrane proteins. Eleven family members within a single H. pylori strain, predicted to encode proteins with substantial N- and C-terminal similarity to each other, were classified as babA paralogues. In their central regions, most are less than 54% related to one another. Examining the babA and babB central regions in 42 H. pylori strains from different geographic locales, we ide
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45

Abbott, Andrea M., Tobin Joel Crill Strom, Nadia Saeed, Ravi Shridhar, Sarah E. Hoffe, Khaldoun Almhanna, and Kenneth L. Meredith. "Robotic-assisted Ivor-Lewis esophagectomy in the elderly patient." Journal of Clinical Oncology 32, no. 3_suppl (January 20, 2014): 93. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.93.

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93 Background: Esophageal cancer continues to increase in incidence worldwide with the age of diagnosis continuing to move towards an older onset. Robotic assisted approaches to esophagectomy have demonstrated decreased complications and length of hospitalization (LOH). We sought to examine the impact of age on outcomes in patients undergoing robotic assisted esophagectomy (RAIL). Methods: From 2009-2013, we identified patients undergoing robotic assisted Ivor Lewis esophagectomy. Patients were then stratified according to 3 age groups. Cohort 1, age less then 50, cohort 2, age 50-70, and coho
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46

Sakarya, Ahmet Hamdi, Nicholas Thu Khoa Do, Yen-Lin Huang, Johnny Chuieng-Yi Lu, Tommy Nai-Jen Chang, and David Chwei-Chin Chuang. "Effect of Degree of Arterial Inflow on a Functioning Free Muscle Transplantation in a Rat Gracilis Model." Journal of Reconstructive Microsurgery 36, no. 06 (March 23, 2020): 458–65. http://dx.doi.org/10.1055/s-0040-1703016.

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Abstract Background Various surgical effects have previously been studied in an attempt to improve the functional outcome of the functioning free muscle transplantation (FFMT). However, the effect of the recipient arterial inflow on the FFMT has remained uninvestigated. This study was to investigate whether or not high flow versus low flow will affect the functional outcome of FFMT. Methods Rat's left gracilis FFMT model was devised and the nutrient arterial inflow was modified. Twenty-four Lewis rats were divided evenly into relatively high (0.071 mL/min) and relatively low (0.031 mL/min) blo
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47

Delbaere, Louis T. J., Margaret Vandonselaar, Lata Prasad, J. Wilson Quail, Joyce R. Pearlstone, Michael R. Carpenter, Lawrence B. Smillie, Pandurang V. Nikrad, Ulrike Spohr, and Raymond U. Lemieux. "Molecular recognition of a human blood group determinant by a plant lectin." Canadian Journal of Chemistry 68, no. 7 (July 1, 1990): 1116–21. http://dx.doi.org/10.1139/v90-172.

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The lectin IV of Griffoniasimplicifolia (GS4) specifically binds the terminal tetrasaccharide unit of the Lewis b human blood group determinant (Leb). The single crystal X-ray analysis of the complex with Leb-OMe has demonstrated that the binding site on the lectin is a shallow depression with a negatively charged aspartate side chain at the bottom of the cavity. In addition to this aspartate, a serine and an asparagine side chain provide the polar groups that hydrogen bond to the three hydroxyl groups of Leb, which has been termed the key polar grouping for complex formation. A notable charac
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48

Dykes, Josefina H., Britt Thuresson, Louise Edvardsson, Tor Olofsson, and Martin L. Olsson. "Transcriptional Profile of Carbohydrate Blood Group Genes in Erythroid Versus Neutrophil Differentiation of Human CD34+ Cells In Vitro." Blood 106, no. 11 (November 16, 2005): 4242. http://dx.doi.org/10.1182/blood.v106.11.4242.4242.

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Abstract Carbohydrate blood groups and their corresponding antibodies are clinically important, known to be involved in conditions such as hemolytic transfusion reactions, hemolytic disease of the newborn and spontaneous abortion. However, little is understood about the developmental changes in expression of carbohydrate blood groups during hematopoiesis, with preceding studies mainly focusing on protein-based blood group molecules. We have previously identified the carbohydrate blood group A antigen as the earliest, specific marker for definitive erythroid commitment, in preference to other s
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49

Othman, Rgia A., Miyoung Suh, Gabor Fischer, Nazila Azordegan, Natalie Riediger, Khuong Le, Davinder S. Jassal, and Mohammed H. Moghadasian. "A comparison of the effects of fish oil and flaxseed oil on cardiac allograft chronic rejection in rats." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 3 (March 2008): H1452—H1458. http://dx.doi.org/10.1152/ajpheart.01280.2007.

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Both fish and flaxseed oils are major sources of different n-3 fatty acids. Beneficial effects of fish oil on posttransplantation complications have been reported. The current study aimed to compare the effects of flaxseed and fish oils in a rat cardiac allograft model. Male Fischer and Lewis rats were used as donors and recipients, respectively, to generate a heterotopic cardiac allograft model. Animals were randomly assigned into three groups and fed a diet supplemented with 1) 5% (wt/wt) safflower oil (control, n = 7), 2) 5% (wt/wt) flaxseed oil ( n = 8), or 3) 2% (wt/wt) fish oil ( n = 7),
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50

Oberhuber, G., A. Kranz, C. Dejaco, B. Dragosics, I. Mosberger, W. Mayr, and T. Radaszkiewicz. "Blood groups Lewis(b) and ABH expression in gastric mucosa: lack of inter-relation with Helicobacter pylori colonisation and occurrence of gastric MALT lymphoma." Gut 41, no. 1 (July 1, 1997): 37–42. http://dx.doi.org/10.1136/gut.41.1.37.

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