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Tesis sobre el tema "Liver cells Effect of drugs on"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 29 de enero de 2023

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1

Nicholls-Grzemski, Felicity April. "The effect of short-term pretreatment with peroxisome proliferators on the acute toxicity of various toxicants, including paracetamol /." Title page, table of contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phn6158.pdf.

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2

Weng, Yu-I. "Acute and chronic ethanol effects on liver p42/44 mitogen activated protein kinase." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3036867.

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3

Gronert, Álvarez Anna Christina [Verfasser], and Hans-Heinrich [Akademischer Betreuer] Wedemeyer. "Regulatory T cells in liver transplantation : phenotypical characterisation and effects of immunosuppressive drugs / Anna Christina Gronert Álvarez. Klinik für Gastroenterologie, Hepatologie und Endokrinologie der Medizinischen Hochschule Hannover. Betreuer: Hans-Heinrich Wedemeyer." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2014. http://d-nb.info/1050008200/34.

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4

Eng, Heather Sui-Fong. "Evaluating the use of cryopreserved hepatocytes for the prediction of in vivo hepatic clearance /." See Full Text at OhioLINK ETD Center (Requires Adobe Acrobat Reader for viewing), 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1091638312.

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Thesis (M.S.P.)--University of Toledo, 2004.<br>Typescript. "A thesis [submitted] as partial fulfillment of the requirements of the Master of Science degree in Pharmaceutical Sciences." Bibliography: leaves 64-68.

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5

Silberstein, D. J. "The effect of renal failure on the elimination of drugs by the liver." Thesis, University of Leeds, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379649.

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6

Ngamratanapaiboon, Surachai. "Metabolomics investigations of the effect of drugs on mammalian cells." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/41178/.

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Cell-based metabolomics using LC-MS systemizes the study of the uniqueness of small-molecule metabolite (metabolomes) profiles in cellular processes. Cell-based metabolomics can potentially be used in many applications for the study of biological perturbation from stimulants in cellular pathways. The advantages of cell-based metabolomics include ease of control and interpretation when compared to the study of human subjects and animal models. Furthermore, this method can decrease some highly challenging problems that occur in genomics, transcriptomics and proteomics. Nowadays, cell culture in

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7

Abumansour, Hamza M. A. "Quantitative pharmacoproteomics investigation of anti-cancer drugs in mouse : development and optimisation of proteomics workflows for evaluating the effect of anti-cancer drugs on mouse liver." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/15724.

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Minimizing anti-cancer drug toxicity is a major challenge for the pharmaceutical industry. Toxicity is most frequently due to either the direct interaction of the drug on previously unidentified targets or its conversion to metabolites by drug metabolizing enzymes (e.g. CYP450 enzymes) that cause cellular, tissue or organ damage. Pharmacoproteomics is beginning to take a central role in studying changes in protein expression corresponding to drug administration, the results of which, inform about the mode of action, toxicity, and resistance in pre-clinical and clinical stages of drug developme

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8

Teng, Shuzhi, and 滕曙智. "Hepatocellular injury induced by endotoxin and galactosamine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31241037.

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9

Kassahun, Kelem. "Mechanistic studies of valproic acid hepatotoxicity : identification and characterization of thiol conjugates." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/30831.

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The severe hepatotoxicity of the antiepileptic drug valproic acid (VPA) is believed to be mediated through chemically reactive metabolites. The monounsaturated metabolite 4-ene VPA is steatogenic in the rat, and in a similar fashion to the hepatotoxin 4-pentenoic acid, is thought to be oxidized by mitochondria to a highly reactive α,β-unsaturated ketone, 3-keto-4-ene VPA. The tripeptide thiol, glutathione (GSH), is known to react with a variety of electrophilic compounds that have the potential to interact with cellular macromolecules. The identification and structural characterization of GSH

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10

Jansen, Robert Walter. "Modified human serum albumins as carriers for the specific delivery of antiviral drugs to liver- and blood cells." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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11

Abdelhadi, Mohamed Mohamed. "Posttransplantation bone disease : the effect of immunosuppressive drugs on bone: clinical and experimental studies /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-384-8/.

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12

Kita, Sadahiko. "The protective effect of transplanted liver cells into the mesentery on the rescue of acute liver failure after massive hepatectomy." Kyoto University, 2016. http://hdl.handle.net/2433/216179.

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出版日2016/2/15を明示する必要あり。発行号・ページ数が決まっていればそれらも明示する必要あり。 Final publication is available at http://dx.doi.org/10.3727/096368916X690999<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(医学)<br>甲第19925号<br>医博第4145号<br>新制||医||1017(附属図書館)<br>33011<br>京都大学大学院医学研究科医学専攻<br>(主査)教授長船健二, 教授伊達洋至, 教授坂井義治<br>学位規則第4条第1項該当

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13

Smith, Darron Louis. "The effect and mechanism of action of volatile fatty acids on the catabolism of progesterone." Morgantown, W. Va. : [West Virginia University Libraries], 2005. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4243.

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Thesis (Ph. D.)--West Virginia University, 2005.<br>Title from document title page. Document formatted into pages; contains x, 88 p. : ill. Vita. Includes abstract. Includes bibliographical references.

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14

Bunaciu, Rodica Petruta. "THE EFFECT OF POLYCHLORINATED BIPHENYLS ON LIVER TUMOR PROMOTION: A ROLE FOR KUPFFER CELLS?" Lexington, Ky. : [University of Kentucky Libraries], 2005. http://lib.uky.edu/ETD/ukynusi2005d00298/etd.pdf.

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Thesis (Ph. D.)--University of Kentucky, 2005.<br>Title from document title page (viewed on November 4, 2005). Document formatted into pages; contains viii, 188 p. : ill. Includes abstract and vita. Includes bibliographical references (p. 165-184).

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15

Stevens, Jeffrey Charles 1963. "Selective inactivation of four rat liver microsomal androstenedione hydroxylases by chloramphenicol analogs." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276700.

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The steroid androstenedione has been shown to be a valuable tool for the study of selective inactivation of rat liver cytochrome P-450 isozymes. The validity of this method was investigated using microsomes, purified cytochromes P-450, cytochrome P-450 antibodies, and the mechanism-based inactivator chloramphenicol. Enzyme inactivation and antibody inhibition studies show that microsomes from phenobarbital- and non-phenobarbital-treated rats are needed to accurately monitor the inactivation of the major phenobarbital-inducible P-450 isozyme (PB-B) and of the major constitutive androstenedione

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16

Vaino, Andrew Rein. "Synthesis of agents for the targeting of drugs to the human liver and elucidation of the reverse anomeric effect." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ31959.pdf.

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17

Müller, Daniel [Verfasser], and Elmar [Akademischer Betreuer] Heinzle. "Organotypic functional cultures of human liver cells for long-term maintenance and assessment of drug-induced metabolome effects / Daniel Müller. Betreuer: Elmar Heinzle." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2012. http://d-nb.info/1052338445/34.

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18

Charanek, Ahmad. "The Bile Canaliculus Revisited : Morphological And Functional Alterations Induced By Cholestatic Drugs In HepaRG Cells." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1B011/document.

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La cholestase est l'une des manifestations les plus courantes des lésions induitespar des médicaments. Dans 40% des cas elle n’est pas prévisible; une meilleure prédictibilité représente donc un défi majeur. Tout d'abord, nous avons démontré que les cellules hépatiques humaines HepaRG différenciées sont un modèle approprié pour étudier la cholestase induite par les médicaments en comparant la localisation et l’activité des transporteurs d'influx et d'efflux avec les hépatocytes humains primaires. Tous les transporteurs d'efflux et d’influx testés ont été correctement localisés au niveau des me

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19

Davies, Richard. "Effect of selective COX-2 inhibitors on hepatic progenitor cells and the pathologies of experimental hepatocarcinogenesis." University of Western Australia. School of Medicine and Pharmacology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0190.

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[Truncated abstract] Hepatocellular carcinoma (HCC) is the major malignancy complicating chronic liver disease. New therapies for the prevention of HCC are required due to the limited success and high tumour recurrence rates of existing treatments. Emerging evidence suggests that HCC arise from the transformation of adult liver progenitor cells (LPCs), which have the capacity to differentiate into hepatocytes and biliary cells during liver regeneration. LPC activation precedes neoplasia in experimental hepatocarcinogenesis. LPCs share antigenic epitopes with HCCs, including α-fetoprotein (AFP)

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20

廖寶韶 and Po-shiu Jackie Liu. "Effects of flavonoids on proliferation of breast cancer cells and vascular smooth muscle cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B45011394.

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21

Almaawi, Abdulaziz. "Effect of acetaminophen and nonsteroidal anti-inflammatory drugs on gene expression of human mesenchymal stem cells." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114405.

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A major drawback of cartilage tissue engineering is that human mesenchymalStem cells (MSCs) from patients with osteoarthritis (OA) express high levels of type X collagen. Type X collagen is a marker of late stage chondrocyte hypertrophy, linked with endochondral ossification. Also, MSCs from OA patients express osteogenic marker genes such as alkaline phosphatase (ALK), bone sialoprotein (BSP), and osteocalcin (OC) as well as aggrecan (ACAN), a marker of chondrogenesis, but not type II collagen. OA patients, in an attempt to relieve pain and other symptoms, often take NSAIDs and pain reliever

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22

Al-Mayyahi, Rawaa Salim. "An investigation of the mechanisms underpinning the effect of anti-inflammatory drugs on neural stem cells." Thesis, Keele University, 2017. http://eprints.keele.ac.uk/4257/.

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Anti-inflammatory drugs such as corticosteroids (CSs) and minocycline (MINO) are widely used in the treatment of a range of clinical conditions and to suppress graft rejection in stem cell transplantation therapy. However, such treatment is associated with adverse effects on brain development. The effects of anti-inflammatory drug on neural stem cells (NSCs) are largely unknown and the molecular mechanisms underlying these effects are poorly documented. The focus of this project is to systematically investigate the effects of different anti-inflammatory drug at different concentrations on the

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23

Alaedin, MohamadTaher [Verfasser]. "Effect of an inflammatory stimulus on mitochondrial functionality in liver cells of dairy cows / MohamadTaher Alaedin." Bonn : Universitäts- und Landesbibliothek Bonn, 2021. http://d-nb.info/1238687458/34.

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24

周淑雅 and S. N. Chow. "Investigation of radio- and chemosensitivity mechanisms in Nasopharyngeal Carcinoma cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31224283.

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25

Martinez, Francisca. "The effect of selected drugs on pokeweed mitogen-stimulated IgG synthesis by human peripheral blood mononuclear cells." Thesis, University of Liverpool, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279718.

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26

Ellis, Lucy C. J. "Human and rat multidrug resistance-associated proteins (MRP/Mrp)." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=128325.

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The multidrug resistance associated proteins (MRP(human)Mrp (rat) are ATP-dependent transporters responsible for the efflux of a wide range of substrates, including endogenous compounds e.g. bilirubin, drug metabolites e.g. paracetamol glucuronide and fluorescent dyes e.g. 5 (and 6)-carboxy-2’,7’-dichlorofluorescein (CDF). Mrp1-6 (<i>abccl-6)</i> are expressed in rat liver, with Mrp2 being expressed at the highest level. Isolation of hepatocytes by <i>in situ</i> collagenase perfusion causes bile canalicular disruption and internalisation of Mrp2. Cells cultured in a sandwich configuration of

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27

Cleveland, Beth Marie. "The effect of [alpha]-aminoadipate [delta]-semialdehyde synthase knockdown on the lysine requirement and urate oxidase knockdown on oxidate stress in a murine hepatic cell line." Morgantown, W. Va. : [West Virginia University Libraries], 2007. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5272.

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Thesis (Ph. D.)--West Virginia University, 2007.<br>Title from document title page. Document formatted into pages; contains vii, 112 p. : ill. (some col.). Includes abstract. Includes bibliographical references.

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28

Segolela, Jane Choene. "Potential effect of senna italica on glucose transport receptors - translocation go GLUT4 in NIH-3T3-L1 preadipocytes and C2C12 muscle cells." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1558.

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Thesis (M. Sc. (Biochemistry)) -- University of Limpopo, 2015<br>Diabetes mellitus is one of the major diseases worldwide that is life threatening and is reaching an epidemic proportion. The most important approach in reducing the burden of the disease worldwide is to search for effective, low cost hypoglycaemic drugs with fewer side effects. Past experimental evidence confirmed the hypoglycemic activity of many indigenous African medicinal plants. S. italica (Fabaceae family) is widely used by traditional healers to treat a number of diseases such as sexually transmitted diseases and other fo

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29

張子臣 and Zichen Zhang. "Anticancer effects of hexamethylene bisacetamide on human colon carcinoma cells in vitro." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31239766.

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30

Lau, Ping-woi Echo, and 劉頻迴. "The anti-cancer effect of berberine in a human nasopharyngeal carcinoma cell line HONE 1." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40687697.

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31

Kourjian, Georgio. "Effect of HIV antiretroviral drugs on antigen processing and epitope presentation by MHC-I to cytotoxic T cells." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ027/document.

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L’apprêtement antigénique par les protéases intracellulaires et la présentation des épitopes sont essentiels pour la reconnaissance des cellules infectées par les lymphocytes CD8+. Ici nous avons montré que certains inhibiteurs de la protéase de la VIH (IPs) modulent l’activité de la protéasome et aminopeptidase impliqué dans l’apprêtement antigénique endogène et l’activité cathepsins importante dans l’apprêtement croisée. Deux IPs agissent directement sur les cathepsins et leurs régulateurs en inhibant les activités kinase, NOX2 et en régulant le pH phagolysosomal. Les IPs ont changé la dégra

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32

To, Wing Shu. "Effect of cellular redox and energy states on benzo[a]pyrene induced modes of death in the hepa and the HepG2 cell lines." HKBU Institutional Repository, 2010. http://repository.hkbu.edu.hk/etd_ra/1173.

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33

Allen, Portia SueAnn. "The effect of drugs and nutraceuticals on the prevention and treatment of non-alcoholic fatty liver disease using rats as a model for humans." [Ames, Iowa : Iowa State University], 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1476270.

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34

Zhu, Meifen, and 朱玫芬. "Mir-23a involves in the anti-cancer effect of CRAE and berberine in human hepatocellular carcinoma cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46944771.

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35

劉汝這 and Yue-huen Thomas Lau. "Ultrastructural and stereological investigation of the effects of hexamethylene bisacetamide on human colon carcinoma LoVo cells invitro." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B29872972.

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36

Zhang, Jin 1960. "The influence of copper deficiency on the binding and uptake of high-density lipoprotein by rat hepatic parenchymal cells." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276935.

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This study was designed to examine the influence of Cu deficiency on the binding, uptake, and degradation of apolipoprotein E-free high density lipoproteins (apo E-free HDL) in cultured rat hepatic parenchymal cells. The binding of apo E-free HDL during time course studies was slightly but significantly increased in cells derived from Cu-deficient rats. In saturation studies, the amount of surface-bound apo E-free HDL appeared to be saturable, although no difference was observed between Cu-deficient and adequate animals. The amount of total and specific cell-associated uptake of apo E-free HDL

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37

Okoli, Arinze Stanley Medical Sciences Faculty of Medicine UNSW. "Molecular studies of the response of Helicobacter hepaticus to bile, and the effect of Helicobacter bilis on human hepatoma cells." Publisher:University of New South Wales. Medical Sciences, 2009. http://handle.unsw.edu.au/1959.4/43379.

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Enterohepatic Helicobacter species (EHS) are emerging infectious disease agents. Infection of the enterohepatobiliary tract of several mammals by this group of bacteria results in various pathological disorders. The availability of the Helicobacter hepaticus sequenced and annotated genome, allowed molecular characterisation of the responses of H. hepaticus to host factors such as bile. The adaptation/responses of the bacterium to bovine, porcine and human bile were investigated using proteomics and transcriptomics. Ninety-one different proteins were identified in the responses of H. hepaticus

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38

Caperna, Thomas J. "Metabolism of supplemental iron by hepatic parenchymal and sinusoidal cells of the neonatal pig." Diss., Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/49998.

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Methods were developed to isolate and culture the predominant cell types from porcine liver to investigate hepatic accumulation, distribution and intracellular metabolism of supplemental iron. Hepatocytes were prepared from collagenase perfused livers by differential centrifugation, while Kupffer cells and endothelial cells were isolated by centrifugal elutriation. One day old piglets were injected with iron-dextran (Fe-dextran) and the concentration of accumulated iron was determined in all three cell types 1, 5, and 10 days later. The concentration of iron increased markedly in all three cel

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39

Zhang, Xiaoyan. "The effect of long-term exposure to transforming growth factor-b1 on the spontaneous transformation of cultured rat liver epithelial cells /." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56969.

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In contrast to normal cells, most neoplastic cells are resistant to the growth inhibitory effect of the transforming growth factor-$ beta$(TGF-$ beta$). The neoplastic transformation of cultured rat liver epithelial cells induced spontaneously or by chemical carcinogens and oncogenes is consistently associated with the development of resistance to the mito-inhibitory effect of TGF-$ beta$, suggesting that such phenotype plays an essential role during the transformation of these cells. We have studied the development of this "TGF-$ beta$, resistant" phenotype in a clonal strain of early passage

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40

Cakmak, Gulgun. "The Effects Of Radioprotectant Amifostine On Irradiated Rat Brain And Liver Tissues." Phd thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12612591/index.pdf.

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Amifostine is the only approved radioprotective agent by the Food and Drug Administration for reducing the damaging effects of radiation on healthy tissues. In this study, the effects of ionizing radiation on rat liver microsomal membrane and brain tissue and the protecting effects of amifostine on these systems were investigated at molecular level. Sprague-Dawley rats, which were administered amifostine or not, were whole-body irradiated and liver microsomal membranes and different regions of the brain of these rats were analyzed using FTIR spectroscopy, FTIR microspectroscopy and synchrotron

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41

Murata, Toru. "Inhibitory effect of Y-27632,a ROCK inhibitor,on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells." Kyoto University, 2002. http://hdl.handle.net/2433/149343.

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42

Liao, Ximan, and 廖喜漫. "A study of proteoglycan production during suppressed cell proliferation of a human colon carcinoma cell line." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B3123897X.

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43

Takeda, Yoshihisa. "Morphologic alteration of hepatocytes and sinusoidal endothelial cells in rat fatty liver during cold preservation and the protective effect of hepatocyte growth factor." Kyoto University, 1999. http://hdl.handle.net/2433/181710.

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44

Li, Jing, and 李靜. "Effects of intrinsic & extrinsic factors on the growth and differentiation of human mesenchymal stem cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B37238310.

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45

Roberts, Lindi. "The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells." Master's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/3298.

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Includes bibliographical references (leaves 92-109).<br>The precise mechanisms of action of the quinoline anti-malarial drugs are uncertain, although they have been found to influence endocytosis, vesicular processing and secretion in malarial parasites and mammalian cells. In this study, the effects of chloroquine, amadiaquine, halofantrine, mefloquine and quinine on the endolysosomal systems in Plasmodium falciparum 3D7, Dictyostelium discoideum and A549 pulmonary cancer cells were examined.

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46

Tron, Camille. "Étude des relations entre concentrations sanguines, biliaires, intracellulaires, et effet immunosuppresseur du tacrolimus en transplantation hépatique." Thesis, Rennes 1, 2019. http://www.theses.fr/2019REN1B038.

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Le tacrolimus est la pierre angulaire du traitement préventif du rejet de greffe en transplantation hépatique. Les posologies de tacrolimus doivent être adaptées aux patients en fonction des concentrations résiduelles sanguines mesurées tout au long du traitement. Cependant, ce suivi thérapeutique pharmacologique présente des limites puisque la réponse au tacrolimus n’est pas optimale chez tous les patients. Dans ce contexte, ce travail avait pour objectifs d’évaluer l’intérêt de nouveaux biomarqueurs de suivi pharmacologique du tacrolimus chez les patients transplantés hépatiques. Un premier

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47

Paun, Andrea. "Regulator T cells in murine AIDS." University of Western Australia. Microbiology and Immunology Discipline Group, 2005. http://theses.library.uwa.edu.au/adt-WU2005.0115.

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[Truncated abstract] In the last ten years regulator T (Tr) cells have re-emerged as an integral part of the immune system. Research in this field has rapidly demonstrated the role of these cells in the maintenance of immune homeostasis and their involvement in disease. Tr cells are generated in the thymus as a normal part of the developing immune system. Furthermore, antigen-specific Tr cells are induced in the periphery by a mechanism which is yet to be completely elucidated, but is likely to involve dendritic cells. Tr cells play an important role in autoimmune disease, transplantation tol

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48

Nicholls-Grzemski, Felicity April. "The effect of short-term pretreatment with peroxisome proliferators on the acute toxicity of various toxicants, including paracetamol / Felicity April Nicholls-Grzemski." Thesis, 1998. http://hdl.handle.net/2440/19434.

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Erratum tipped in before chapter 1.<br>Bibliography: leaves 226-248.<br>xv, 248 leaves : ill. (chiefly col.) ; 30 cm.<br>Shows that pretreatment with peroxisome proliferators protects mice against the acute hepatotoxicity of paracetamol, in addition to a number of other toxicants.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 1999

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Bruschi, Sam A. (Sam Anthony). "Investigations into mechanisms of paracetamol-induced toxicity using ìn vitro' systems." 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phb192.pdf.

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Bruschi, Sam A. (Sam Anthony). "Investigations into mechanisms of paracetamol-induced toxicity using in vitro' systems / by Sam A. Bruschi." 1987. http://hdl.handle.net/2440/18564.

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Bibliography: leaves 116-138<br>[14], 138 leaves, 5 leaves of plates : ill ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Clinical & Experimental Pharmacology, 1988

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