Artículos de revistas: "Long non-coding RNA"

1

TAKAHASHI, Kenji, Yohei KITANO, Yuichi MAKINO y Masakazu HANEDA. "Long non-coding RNAs in pancreatic cancer". Suizo 31, n.º 1 (2016): 32–40. http://dx.doi.org/10.2958/suizo.31.32.

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2

Ma, Xiaoxia, Chaogang Shao, Yongfeng Jin, Huizhong Wang y Yijun Meng. "Long non-coding RNAs". RNA Biology 11, n.º 4 (abril de 2014): 373–90. http://dx.doi.org/10.4161/rna.28725.

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3

Kazimierczyk, Marek y Jan Wrzesinski. "Long Non-Coding RNA Epigenetics". International Journal of Molecular Sciences 22, n.º 11 (7 de junio de 2021): 6166. http://dx.doi.org/10.3390/ijms22116166.

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Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in ensuring cell functions and proper organism development by interacting with cellular compounds such as miRNA, mRNA, DNA and proteins. However, there is an additional level of lncRNA regulation, called lncRNA epigenetics, in gene expression control. In this review, we describe the most common modified nucleosides found in lncRNA, 6-methyladenosine, 5-methylcytidine, pseudouridine and inosine. The biosynthetic pathways of these nucleosides modified by the writer, eraser and reader enzymes are important to understanding these processes. The characteristics of the individual methylases, pseudouridine synthases and adenine–inosine editing enzymes and the methods of lncRNA epigenetics for the detection of modified nucleosides, as well as the advantages and disadvantages of these methods, are discussed in detail. The final sections are devoted to the role of modifications in the most abundant lncRNAs and their functions in pathogenic processes.

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4

Stower, Hannah. "Long non-coding RNA stability". Nature Reviews Genetics 13, n.º 5 (12 de abril de 2012): 298. http://dx.doi.org/10.1038/nrg3234.

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5

Beylerli, O. A. y I. F. Gareev. "Long non-coding RNA — perspectives?" Profilakticheskaya meditsina 23, n.º 2 (2020): 124. http://dx.doi.org/10.17116/profmed202023021124.

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6

GAO, Yuan, Ning HUI y Shan-rong LIU. "Long non-coding RNA: research progress". Academic Journal of Second Military Medical University 31, n.º 7 (26 de diciembre de 2011): 790–94. http://dx.doi.org/10.3724/sp.j.1008.2011.00790.

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7

Hauptman, Nina y Damjan Glavač. "Long Non-Coding RNA in Cancer". International Journal of Molecular Sciences 14, n.º 3 (26 de febrero de 2013): 4655–69. http://dx.doi.org/10.3390/ijms14034655.

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8

Zhang, J., X. Hao, M. Yin, T. Xu y F. Guo. "Long non-coding RNA in osteogenesis". Bone & Joint Research 8, n.º 2 (febrero de 2019): 73–80. http://dx.doi.org/10.1302/2046-3758.82.bjr-2018-0074.r1.

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9

Saxena, Alka y Piero Carninci. "Long non-coding RNA modifies chromatin". BioEssays 33, n.º 11 (14 de septiembre de 2011): 830–39. http://dx.doi.org/10.1002/bies.201100084.

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10

Aurilia, Cinzia, Gaia Palmini, Simone Donati, Irene Falsetti, Teresa Iantomasi y Maria Luisa Brandi. "Long non coding RNA in osteoporosis". International Journal of Bone Fragility 2, n.º 3 (28 de diciembre de 2022): 102–5. http://dx.doi.org/10.57582/ijbf.220203.102.

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Osteoporosis (OP) is the most common skeletal disease, caused by a lack of balance between osteoclast and osteoblast activity. This results in erosion overriding the deposition of new bone matrix, consequently leading to low-quality bone and an increased risk of incurring fragility fractures. Dual energy X-ray absorptiometry is the gold standard for the diagnosis of OP, while anti-osteoporotic drugs are the gold standard for its treatment. However, due to limitations to their use, researchers have turned to epigenetics as a substantial source of molecules that could potentially be used as diagnostic, prognostic, and therapeutic biomarkers for OP. In particular, long non-coding RNAs (lncRNAs) possess special biological properties that could open new horizons in the field of personalized medicine. This mini review seeks to offer an overview of the studies carried out in the last year on the different lncRNAs that could be involved in the pathogenesis of OP and that could pave the way for the development of innovative therapeutic strategies for this disease.

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11

蔡, 雅莉. "Research Progress of Long Non-Coding RNA". International Journal of Psychiatry and Neurology 05, n.º 03 (2016): 54–58. http://dx.doi.org/10.12677/ijpn.2016.53009.

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12

IWAKIRI, Junichi y Michiaki HAMADA. "Computational Approaches for Long Non-coding RNA Research". Seibutsu Butsuri 56, n.º 4 (2016): 217–20. http://dx.doi.org/10.2142/biophys.56.217.

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13

Zhang, Tianzhu, Hui Hu, Ge Yan, Tangwei Wu, Shuiyi Liu, Weiqun Chen, Yong Ning y Zhongxin Lu. "Long Non-Coding RNA and Breast Cancer". Technology in Cancer Research & Treatment 18 (1 de enero de 2019): 153303381984388. http://dx.doi.org/10.1177/1533033819843889.

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Breast cancer, one of the most common diseases among women, is regarded as a heterogeneous and complicated disease that remains a major public health concern. Recently, owing to the development of next-generation sequencing technologies, long non-coding RNAs have received extensive attention. Numerous studies reveal that long non-coding RNAs are playing important roles in tumor development. Although the biological function and molecular mechanisms of long non-coding RNAs remain enigmatic, recent researchers have demonstrated that an array of long non-coding RNAs express abnormally in cancers, including breast cancer. Herein, we summarized the latest literature about long non-coding RNAs in breast cancer, with a particular focus on the multiple molecular roles of regulatory long non-coding RNAs that regulate cell proliferation, invasion, metastasis, and apoptosis.

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14

Arun, Gayatri, Disha Aggarwal y David L. Spector. "MALAT1 Long Non-Coding RNA: Functional Implications". Non-Coding RNA 6, n.º 2 (3 de junio de 2020): 22. http://dx.doi.org/10.3390/ncrna6020022.

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The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is one of the most well-studied lncRNAs. MALAT1 is a highly conserved nuclear retained lncRNA that is abundantly expressed in cells and tissues and has been shown to play a role in regulating genes at both the transcriptional and post-transcriptional levels in a context-dependent manner. However, Malat1 has been shown to be dispensable for normal development and viability in mice. Interestingly, accumulating evidence suggests that MALAT1 plays an important role in numerous diseases including cancer. Here, we discuss the current state-of-knowledge in regard to MALAT1 with respect to its function, role in diseases, and the potential therapeutic opportunities for targeting MALAT1 using antisense oligonucleotides and small molecules.

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15

Cruz-Miranda, Gabriela, Alfredo Hidalgo-Miranda, Diego Bárcenas-López, Juan Núñez-Enríquez, Julian Ramírez-Bello, Juan Mejía-Aranguré y Silvia Jiménez-Morales. "Long Non-Coding RNA and Acute Leukemia". International Journal of Molecular Sciences 20, n.º 3 (9 de febrero de 2019): 735. http://dx.doi.org/10.3390/ijms20030735.

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Acute leukemia (AL) is the main type of cancer in children worldwide. Mortality by this disease is high in developing countries and its etiology remains unanswered. Evidences showing the role of the long non-coding RNAs (lncRNAs) in the pathophysiology of hematological malignancies have increased drastically in the last decade. In addition to the contribution of these lncRNAs in leukemogenesis, recent studies have suggested that lncRNAs could be used as biomarkers in the diagnosis, prognosis, and therapeutic response in leukemia patients. The focus of this review is to describe the functional classification, biogenesis, and the role of lncRNAs in leukemogenesis, to summarize the evidence about the lncRNAs which are playing a role in AL, and how these genes could be useful as potential therapeutic targets.

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16

Han, Pei y Ching-Pin Chang. "Long non-coding RNA and chromatin remodeling". RNA Biology 12, n.º 10 (14 de septiembre de 2015): 1094–98. http://dx.doi.org/10.1080/15476286.2015.1063770.

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17

Heaton, Nicholas S. y Bryan R. Cullen. "Viruses hijack a long non-coding RNA". Nature 552, n.º 7684 (diciembre de 2017): 184–85. http://dx.doi.org/10.1038/d41586-017-07692-w.

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18

Diederichs, S. "52: Long non-coding RNA and cancer". European Journal of Cancer 50 (julio de 2014): S13. http://dx.doi.org/10.1016/s0959-8049(14)50052-4.

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19

Kosinska-Selbi, B., M. Mielczarek y J. Szyda. "Review: Long non-coding RNA in livestock". Animal 14, n.º 10 (2020): 2003–13. http://dx.doi.org/10.1017/s1751731120000841.

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20

Fathizadeh, Hadis, Seyed Mohammad Gheibi Hayat, Sounkalo Dao, Khudaverdi Ganbarov, Asghar Tanomand, Mohammad Asgharzadeh y Hossein Samadi Kafil. "Long non-coding RNA molecules in tuberculosis". International Journal of Biological Macromolecules 156 (agosto de 2020): 340–46. http://dx.doi.org/10.1016/j.ijbiomac.2020.04.030.

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21

Cui, Ming, Lei You, Xiaoxia Ren, Wenjing Zhao, Quan Liao y Yupei Zhao. "Long non-coding RNA PVT1 and cancer". Biochemical and Biophysical Research Communications 471, n.º 1 (febrero de 2016): 10–14. http://dx.doi.org/10.1016/j.bbrc.2015.12.101.

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22

Gibb, Ewan A., Emily A. Vucic, Katey S. S. Enfield, Greg L. Stewart, Kim M. Lonergan, Jennifer Y. Kennett, Daiana D. Becker-Santos et al. "Human Cancer Long Non-Coding RNA Transcriptomes". PLoS ONE 6, n.º 10 (3 de octubre de 2011): e25915. http://dx.doi.org/10.1371/journal.pone.0025915.

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23

Jin, J., J. Liu, H. Wang, L. Wong y N. H. Chua. "PLncDB: plant long non-coding RNA database". Bioinformatics 29, n.º 8 (7 de marzo de 2013): 1068–71. http://dx.doi.org/10.1093/bioinformatics/btt107.

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24

Cerase, Andrea y Gian Gaetano Tartaglia. "Long non-coding RNA-polycomb intimate rendezvous". Open Biology 10, n.º 9 (septiembre de 2020): 200126. http://dx.doi.org/10.1098/rsob.200126.

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The interaction between polycomb-repressive complexes 1/2 (PRC1/2) and long non-coding RNA (lncRNA), such as the X inactive specific transcript Xist and the HOX transcript antisense RNA (HOTAIR), has been the subject of intense debate. While cross-linking, immuno-precipitation and super-resolution microscopy argue against direct interaction of Polycomb with some lncRNAs, there is increasing evidence supporting the ability of both PRC1 and PRC2 to functionally associate with RNA. Recent data indicate that these interactions are in most cases spurious, but nonetheless crucial for a number of cellular activities. In this review, we suggest that while PRC1/2 recruitment by HOTAIR might be direct, in the case of Xist , it might occur indirectly and, at least in part, through the process of liquid–liquid phase separation. We present recent models of lncRNA-mediated PRC1/2 recruitment to their targets and describe potential RNA-mediated roles in the three-dimensional organization of the nucleus.

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25

Yoshimoto, Rei, Akila Mayeda, Minoru Yoshida y Shinichi Nakagawa. "MALAT1 long non-coding RNA in cancer". Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1859, n.º 1 (enero de 2016): 192–99. http://dx.doi.org/10.1016/j.bbagrm.2015.09.012.

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26

Chen, Zhenyao, Tianyao Lei, Xin Chen, Jingyao Gu, Jiali Huang, Binbin Lu y Zhaoxia Wang. "Long non-coding RNA in lung cancer". Clinica Chimica Acta 504 (mayo de 2020): 190–200. http://dx.doi.org/10.1016/j.cca.2019.11.031.

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27

Luo, Lingli, Min Wang, Xianping Li, Jingjing Tian, Kan Zhang, Shan Tan y Can Luo. "Long non-coding RNA LOC285194 in cancer". Clinica Chimica Acta 502 (marzo de 2020): 1–8. http://dx.doi.org/10.1016/j.cca.2019.12.004.

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28

Cao, Yuepeng, Tian Tian, Weijian Li, Hanzi Xu, Chuanfei Zhan, Xuhong Wu, Chao Wang et al. "Long non-coding RNA in bladder cancer". Clinica Chimica Acta 503 (abril de 2020): 113–21. http://dx.doi.org/10.1016/j.cca.2020.01.008.

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29

Zou, Yuanzhang y Binghai Chen. "Long non-coding RNA HCP5 in cancer". Clinica Chimica Acta 512 (enero de 2021): 33–39. http://dx.doi.org/10.1016/j.cca.2020.11.015.

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30

Li, Chenyang, Lujia Cui, Siqiong Li, Minrui Li y Xinpu Miao. "Long non‑coding RNA Mirt2 interacts with long non‑coding RNA IFNG‑AS1 to regulate ulcerative colitis". Experimental and Therapeutic Medicine 20, n.º 5 (1 de septiembre de 2020): 1. http://dx.doi.org/10.3892/etm.2020.9159.

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31

Liu, Xiu-Fen, Ji-Long Hao, Tian Xie, Om Prakash Pant, Cheng-Bo Lu, Cheng-Wei Lu y Dan-Dan Zhou. "The BRAF activated non-coding RNA: A pivotal long non-coding RNA in human malignancies". Cell Proliferation 51, n.º 4 (27 de febrero de 2018): e12449. http://dx.doi.org/10.1111/cpr.12449.

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32

Ma, Lina, Vladimir B. Bajic y Zhang Zhang. "On the classification of long non-coding RNAs". RNA Biology 10, n.º 6 (junio de 2013): 924–33. http://dx.doi.org/10.4161/rna.24604.

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33

Jing, Fangyuan, Huicheng Jin, Yingying Mao, Yingjun Li, Ye Ding, Chunhong Fan y Kun Chen. "Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer". Tumor Biology 39, n.º 5 (mayo de 2017): 101042831770365. http://dx.doi.org/10.1177/1010428317703650.

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Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood. The aim of this study was to investigate the long non-coding RNA expression profile in colorectal cancer and look for potential diagnostic biomarkers of colorectal cancer. Long non-coding RNA microarray was applied to investigate the global long non-coding RNA expression profile in colorectal cancer. Gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were performed using standard enrichment computational methods. The expression levels of selected long non-coding RNAs were validated by quantitative reverse transcription polymerase chain reaction. The relationship between long non-coding RNA expression levels and clinicopathological characteristics of colorectal cancer patients was assessed. Coexpression analyses were carried out to find the coexpressed genes of differentially expressed long non-coding RNAs, followed by gene ontology analysis to predict the possible role of the selected long non-coding RNAs in colorectal carcinogenesis. In this study, a total of 1596 long non-coding RNA transcripts and 1866 messenger RNA transcripts were dysregulated in tumor tissues compared with paired normal tissues. The top upregulated long non-coding RNAs in tumor tissues were CCAT1, UCA1, RP5-881L22.5, NOS2P3, and BC005081 and the top downregulated long non-coding RNAs were AK055386, AC078941.1, RP4-800J21.3, RP11-628E19.3, and RP11-384P7.7. Long non-coding RNA UCA1 was significantly upregulated in colon cancer, and AK055386 was significantly downregulated in tumor with dimension <5 cm. Functional prediction analyses showed that both the long non-coding RNAs coexpress with cell cycle related messenger RNAs. The current long non-coding RNA study provided novel insights into expression profile in colorectal cancer and predicted the potential roles of long non-coding RNAs in colorectal carcinogenesis. Among the dysregulated long non-coding RNAs, UCA1 was found to be associated with anatomic site, and AK055386 was found associated with tumor size. Further functional investigations into the molecular mechanisms are warranted to clarify the role of long non-coding RNA in colorectal carcinogenesis.

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34

Yang, Feng, Fan Yi, Zhiguo Zheng, Zhiqiang Ling, Jianv Ding, Jiangfeng Guo, Weimin Mao et al. "Characterization of a carcinogenesis-associated long non-coding RNA". RNA Biology 9, n.º 1 (enero de 2012): 110–16. http://dx.doi.org/10.4161/rna.9.1.18332.

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35

Amort, Thomas, Marie F. Soulière, Alexandra Wille, Xi-Yu Jia, Heidi Fiegl, Hildegard Wörle, Ronald Micura y Alexandra Lusser. "Long non-coding RNAs as targets for cytosine methylation". RNA Biology 10, n.º 6 (junio de 2013): 1002–8. http://dx.doi.org/10.4161/rna.24454.

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36

Vallot, Céline y Claire Rougeulle. "Long non-coding RNAs and human X-chromosome regulation". RNA Biology 10, n.º 8 (agosto de 2013): 1262–65. http://dx.doi.org/10.4161/rna.25802.

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37

Mattick, John S. "The State of Long Non-Coding RNA Biology". Non-Coding RNA 4, n.º 3 (10 de agosto de 2018): 17. http://dx.doi.org/10.3390/ncrna4030017.

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Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals and other complex organisms is expressed in highly dynamic and cell-specific patterns to produce large numbers of intergenic, antisense and intronic long non-protein-coding RNAs (lncRNAs). Despite well characterized examples, their scaling with developmental complexity, and many demonstrations of their association with cellular processes, development and diseases, lncRNAs are still to be widely accepted as major players in gene regulation. This may reflect an underappreciation of the extent and precision of the epigenetic control of differentiation and development, where lncRNAs appear to have a central role, likely as organizational and guide molecules: most lncRNAs are nuclear-localized and chromatin-associated, with some involved in the formation of specialized subcellular domains. I suggest that a reassessment of the conceptual framework of genetic information and gene expression in the 4-dimensional ontogeny of spatially organized multicellular organisms is required. Together with this and further studies on their biology, the key challenges now are to determine the structure–function relationships of lncRNAs, which may be aided by emerging evidence of their modular structure, the role of RNA editing and modification in enabling epigenetic plasticity, and the role of RNA signaling in transgenerational inheritance of experience.

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38

Khan, Salman, Mohammad Masood, Harshita Gaur, Shaniya Ahmad y Mansoor Ali Syed. "Long non-coding RNA: An immune cells perspective". Life Sciences 271 (abril de 2021): 119152. http://dx.doi.org/10.1016/j.lfs.2021.119152.

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39

Ye, Tao, Xiaoqi Yang, Haoran Liu, Peng Lv y Zhangqun Ye. "Long Non-Coding RNA BLACAT1 in Human Cancers". OncoTargets and Therapy Volume 13 (agosto de 2020): 8263–72. http://dx.doi.org/10.2147/ott.s261461.

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40

Flippot, Ronan, Gabriel G. Malouf, Xiaoping Su, Roger Mouawad, Jean-Philippe Spano y David Khayat. "Cancer subtypes classification using long non-coding RNA". Oncotarget 7, n.º 33 (21 de junio de 2016): 54082–93. http://dx.doi.org/10.18632/oncotarget.10213.

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41

Hsieh, Pei-Fang, Cheng-Chia Yu, Pei-Ming Chu y Pei-Ling Hsieh. "Long Non-Coding RNA MEG3 in Cellular Stemness". International Journal of Molecular Sciences 22, n.º 10 (19 de mayo de 2021): 5348. http://dx.doi.org/10.3390/ijms22105348.

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Long non-coding RNAs (lncRNAs) regulate a diverse array of cellular processes at the transcriptional, post-transcriptional, translational, and post-translational levels. Accumulating evidence suggests that lncRNA MEG3 exerts a large repertoire of regulatory functions in cellular stemness. This review focuses on the molecular mechanisms by which lncRNA MEG3 functions as a signal, scaffold, guide, and decoy for multi-lineage differentiation and even cancer progression. The role of MEG3 in various types of stem cells and cancer stem cells is discussed. Here, we provide an overview of the functional versatility of lncRNA MEG3 in modulating pluripotency, differentiation, and cancer stemness.

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42

Shi, Jia, Bo Dong, Jiachao Cao, Yumin Mao, Wei Guan, Ya Peng y Suinuan Wang. "Long non-coding RNA in glioma: signaling pathways". Oncotarget 8, n.º 16 (7 de febrero de 2017): 27582–92. http://dx.doi.org/10.18632/oncotarget.15175.

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43

Arun, Gayatri y David L. Spector. "MALAT1 long non-coding RNA and breast cancer". RNA Biology 16, n.º 6 (22 de marzo de 2019): 860–63. http://dx.doi.org/10.1080/15476286.2019.1592072.

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44

Strano, Sabrina, Sara Donzelli y Giovanni Blandino. "Long non-coding RNA MALAT1 as metastasis suppressor". Precision Cancer Medicine 2 (febrero de 2019): 4. http://dx.doi.org/10.21037/pcm.2019.02.02.

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45

Ghafouri-Fard, Soudeh y Mohammad Taheri. "Long non-coding RNA signature in gastric cancer". Experimental and Molecular Pathology 113 (abril de 2020): 104365. http://dx.doi.org/10.1016/j.yexmp.2019.104365.

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46

Ilott, Nicholas E. y Chris P. Ponting. "Predicting long non-coding RNAs using RNA sequencing". Methods 63, n.º 1 (septiembre de 2013): 50–59. http://dx.doi.org/10.1016/j.ymeth.2013.03.019.

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47

Wang, Ziqiang, Kun Li y Weiren Huang. "Long non-coding RNA NEAT1-centric gene regulation". Cellular and Molecular Life Sciences 77, n.º 19 (26 de marzo de 2020): 3769–79. http://dx.doi.org/10.1007/s00018-020-03503-0.

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48

Palmieri, Giuseppe, Panagiotis Paliogiannis, Maria Cristina Sini, Antonella Manca, Grazia Palomba, Valentina Doneddu, Francesco Tanda, Maria Rosa Pascale y Antonio Cossu. "Long non-coding RNA CASC2 in human cancer". Critical Reviews in Oncology/Hematology 111 (marzo de 2017): 31–38. http://dx.doi.org/10.1016/j.critrevonc.2017.01.003.

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49

Qi, WenChuan, Xu Song y Ling Li. "Long non-coding RNA-guided regulation in organisms". Science China Life Sciences 56, n.º 10 (octubre de 2013): 891–96. http://dx.doi.org/10.1007/s11427-013-4558-1.

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50

Huang, Bo. "Long non-coding RNA: dancing on immune stage". Science China Life Sciences 57, n.º 6 (15 de mayo de 2014): 643–44. http://dx.doi.org/10.1007/s11427-014-4669-3.

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Artículos de revistas sobre el tema "Long non-coding RNA"

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