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Tesis sobre el tema "Manic depressive illness"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 1 de agosto de 2024

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1

Montgomery, Leigh Ann. "The relationship between the health belief model constructs and medication compliance in the treatment of bipolar disorder." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3034938.

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2

Philadelphia, William A. "Persons with serious mental illness and employment." Auburn, Ala., 2007. http://repo.lib.auburn.edu/07M%20Dissertations/PHILADELPHIA_WILLIAM_39.pdf.

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3

Stols, Gabriël Jacobus. "Paediatric bipolar disorder and the lived experience of parents: a systematic review." Thesis, Nelson Mandela Metropolitan University, 2015. http://hdl.handle.net/10948/6040.

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Many international studies have been conducted on paediatric bipolar disorder, but few research studies have been conducted on parenting a child diagnosed with bipolar disorder, both on an international and national level. The researcher utilised Bronfenbrenner’s Ecological Systems Theory as the theoretical framework in exploring and describing this research field. The study has been conducted by means of a systematic review and all of the articles included in the review examined some aspect of parenting and paediatric bipolar disorder. The articles were systematically assessed, and six themes

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4

Chabler, Leslie Anne. "Familial factors in bipolar disorder." Connect to resource, 1987. http://rave.ohiolink.edu/etdc/view.cgi?acc%5Fnum=osu1244209127.

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5

Ng, Ho-yee, and 伍浩沂. "Sleep-wake disturbance in people with interepisode bipolar disorder." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208056.

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6

Peeters, Jennie. "What school teachers should know about bipolar disorder." Online version, 2008. http://www.uwstout.edu/lib/thesis/2008/2008peetersj.pdf.

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7

Nemcek, Laura A. "The Mood and Behavior Rating Scale for Youth - Parent Form (MBRSY-PF) : a parent informant questionnaire to assess for bipolar disorder in children and adolescents /." Online version of thesis, 2008. http://hdl.handle.net/1850/6298.

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8

Edenfield, Teresa M. "Exercise and Mood: Exploring the Role of Exercise in Regulating Stress Reactivity in Bipolar Disorder." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/EdenfieldTM2007.pdf.

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9

Nelson, Angela. "School professionals' role in diagnosing children." Menomonie, WI : University of Wisconsin--Stout, 2005. http://www.uwstout.edu/lib/thesis/2005/2005nelsona.pdf.

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10

Edsall, Lee. "The impact of genetic variations in bipolar disorder /." Link to online version, 2006. https://ritdml.rit.edu/dspace/handle/1850/1878.

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11

Alsaif, Murtada. "Central and peripheral proteomic characterisation of bipolar disorder." Thesis, University of Cambridge, 2013. https://www.repository.cam.ac.uk/handle/1810/252286.

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12

Meier, Leslie Yan. "The course of bipolar disorder an examination of episodic and chronic stress and potential moderating and mediating variables /." Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1472131471&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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13

Bennett, Charles B. "Independence of Mania and Depression across 4 Years in Bipolar Disorder." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1505184/.

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If mania and depression are part of the same pathological processes, one would predict that episodes of one prospectively increase the odds of episodes of the other. The aim of the present study was to test this hypothesis. For comparison purposes, their relationship was contrasted to the relationship between mania and periods of psychosis. Exploratory analyses also tested the degree to which episodes of each occur with greater frequency over time (i.e., kindling). Participants for the present study came from the Suffolk County Mental Health Project (N = 628), a study of first-admission patien

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14

Bysouth, Don. "Jolly good nutter: a discursive psychological examination of bipolar disorder in psychotherapeutic interactions." Thesis, Bysouth, Don (2007) Jolly good nutter: a discursive psychological examination of bipolar disorder in psychotherapeutic interactions. PhD thesis, Murdoch University, 2007. https://researchrepository.murdoch.edu.au/id/eprint/496/.

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This dissertation examines how bipolar disorder, a common and disabling psychiatric condition, is made relevant as a participants' concern in a site of massively consequential psychological business - the psychotherapy session. As its central thesis is the claim that the practices by which bipolar disorder gets done as bipolar disorder are invariably absent in most formal accounts of the disorder. In this regard, the dissertation provides an empirically grounded description of a range of discursive practices associated with the doing of bipolar disorder in psychotherapy. This is undertaken fro

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15

Bysouth, Don. ""Jolly good nutter" : a discursive psychological examination of bipolar disorder in psychotherapeutic interactions /." Bysouth, Don (2007) Jolly good nutter: a discursive psychological examination of bipolar disorder in psychotherapeutic interactions. PhD thesis, Murdoch University, 2007. http://researchrepository.murdoch.edu.au/496/.

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This dissertation examines how bipolar disorder, a common and disabling psychiatric condition, is made relevant as a participants' concern in a site of massively consequential psychological business - the psychotherapy session. As its central thesis is the claim that the practices by which bipolar disorder gets done as bipolar disorder are invariably absent in most formal accounts of the disorder. In this regard, the dissertation provides an empirically grounded description of a range of discursive practices associated with the doing of bipolar disorder in psychotherapy. This is undertaken fro

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16

Freeman, Kathleen A. "Language and the making of meaning for individuals diagnosed with bipolar disorder a project based upon an independent investigation /." Click here for text online. Smith College School for Social Work website, 2007. http://hdl.handle.net/10090/1035.

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Thesis (M.S.W.)--Smith College School for Social Work, Northampton, Mass., 2007<br>Thesis submitted in partial fulfillment for the degree of Master of Social Work. Includes bibliographical references (leaves 65-67).

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17

Beauchemin, Kathleen Mary. "Nocturnal psychopathology : sleep, dreaming, mood and light-therapy in bipolar disorder /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq22949.pdf.

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18

Bergeron, Marie-Josée. "Étude généalogique de la schizophrénie et de la psychose maniaco-dépressive dans la région de la Beauce /." Thèse, Chicoutimi : Université du Québec à Chicoutimi, 2001. http://theses.uqac.ca.

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19

Miller, Steven M. "An interhemispheric switch in binocular rivalry and bipolar disorder /." [St. Lucia, Qld.], 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17585.pdf.

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20

Finestone, Michelle. "Die impak van emosionele intelligensie op mensmodelleringsterapie aan 'n jeugdige met bipolere versteuring." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-06282005-144912/.

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21

Johnson, Mark Harvard. "The relationship of mood-state and severity psychopathology to memory processes in paranoid schizophrenic, nonparanoid schizophrenic, bipolar manic and unipolar depressed inpatients /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487260531956406.

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22

Seçer, Kevser Aktaş Özcankaya Ramazan. "Bipolar bozukluk tanılı bireylerde ve kardeşlerinde mizaç ve karakter özellikleri /." Isparta : SDÜ Tıp Fakültesi, 2005. http://tez.sdu.edu.tr/Tezler/TT00232.pdf.

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23

Singh, Nisha. "Identification and characterisation of a lithium mimetic : enzymatic, cellular and animal investigations." Thesis, University of Oxford, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.560908.

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It has been six decades since the discovery of lithium for the treatment of bipolar disorder. There is, as yet, no conclusive evidence as to how lithium produces this therapeutic effect, since it is known to interact with multiple cellular targets. One of the most credible targets is the enzyme, inositol monophosphatase (lMPase), which plays a crucial role in cell signalling. My aim was to find a novel IMPase inhibitor and evaluate it as a possible lithium-like mood stabiliser by using enzyme, cell and whole animal experiments. To achieve this, I created recombinant human and mouse IMPase enzy

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24

Malhi, Gurjhinder Singh Psychiatry Faculty of Medicine UNSW. "Functional magnetic resonance imaging studies in bipolar disorder." Awarded by:University of New South Wales. Psychiatry, 2005. http://handle.unsw.edu.au/1959.4/23299.

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Aim To determine the neural correlates of Bipolar Disorder (BD) using functional Magnetic Resonance Imaging (fMRI) in different phases of the illness. Methods Five fMRI studies were conducted in adult female BD patients and healthy matched comparison subjects. The first two studies examined patients with bipolar depression and hypomania using captioned-pictures to characterize mood-state related patterns of activation. The subsequent three studies investigated BD euthymia using emotional words and faces to identify a potential trait-marker. Results During depression, bipolar patients demonstr

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25

Constant, Peggy. "Alterations of signal transduction in lymphocytes cultured from patients with bipolar disorder." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33738.

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Bipolar disorder is a psychiatric condition which affects up to 1% of the general population and results in episodes of mania and depression. Molecular biological studies have shown that several components of the signal transduction pathways are affected in bipolar illness. However, the precise systems and components involved in the disorder still remain unknown. Our goal was to identify some of the differences in signal transduction pathways of B-lymphocytes. Using cultured lymphocytes obtained from bipolar patients, we found that there exist no difference in the levels of protein kinase C, G

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26

Ng, Roger Man Kin. "Does mental imagery act as an emotional amplifier in bipolar disorders?" Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:d327c209-9d56-4ac5-8c77-610a6d7de8b2.

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Bipolar disorder is characterized by episodes of mania and depression and serious suicidal risks. Recent studies reported high mental imagery susceptibility (general use of imagery in daily life and emotional impact of prospective imagery) in euthymic bipolar patients. This thesis aims to: a) replicate these findings in patients at different phases of bipolar disorder and with varying degrees of bipolarity, and b) explore how mental imagery susceptibility, ruminative processing, and behavioural approach system (BAS) sensitivity interact to amplify mood symptoms. Chapter 1 provides an overview

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27

Malik, Aiysha. "The broad bipolar phenotype : sampling the experience of mood, stress and mental imagery." Thesis, University of Oxford, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.573476.

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The overarching aim of this thesis was to use an experimental psychopathology approach to investigate mood, stress and mental imagery in the Broad Bipolar Phenotype (BPP), defined by the experience of elevated lifetime hypomania. Daily mood reactions to stress have been well explored in psychosis, but the limited research in BD has produced mixed findings. Holmes, Geddes, Colom and Goodwin (2008) hypothesised that mental imagery in BD may amplify emotion and worsen day to day mood extremes. This thesis investigates volunteers ranging across the continuum ofthe BPP in relation to key variables

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28

Tam, Wai-Cheong Carl. "Information Processing in Schizophrenia and Bipolar Disorder: A Discriminant Analysis Study." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc278050/.

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A study was conducted in which a computerized battery of information processing tasks (called the COGLAB) was administered to three subject groups: patients with schizophrenia, patients with bipolar disorder, and normal controls. The tasks included Mueller-Lyer illusion, reaction time, size estimation, Wisconsin Card Sort, backward masking. and Asarnow Continuous Performance.

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29

Bonnín, Roig Caterina del Mar. "Funcionament psicosocial en el trastom bipolar: Factors implicats i seguiment als 4 anys." Doctoral thesis, Universitat de Barcelona, 2011. http://hdl.handle.net/10803/51476.

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El trastorn bipolar és una malaltia altament discapacitant i que té un gran impacte en la vida dels pacients. L’any 2007, el Programa de Trastorn Bipolar de l’Hospital Clínic juntament amb la col•laboració d’altres centres internacionals, va crear una escala anomenada Functioning Assessment Short Test (FAST). Aquest instrument va surgir com a resposta a la necessitat que existia, tant en la pràctica clínica com en la recerca, d’una escala clínica que avalués el funcionament psicosocial dels pacients amb trastorn bipolar. Existeixen moltes escales per mesurar el funcionament psicosocial en les

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30

Smith, Patrick (Patrick M. ). "Medical Comorbidity in the Course of Bipolar Disorder." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc849606/.

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Bipolar disorder is a serious illness affecting approximately 2-4% of the population and is one of the world’s leading causes of disability. In individuals with bipolar disorder, medical comorbidity associated with cardiovascular, respiratory and endocrine disorders is related to increased rates of mortality. Recent updates to multi-system inflammatory related conceptualizations of bipolar disorder focus on the unique power that medical illness and biological processes may play as factors associated with course and outcome in bipolar disorder. The current study examined medical comorbidity and

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31

Matthews, Paul Richard Leonard. "Morphometric and molecular studies of schizophrenia and mood disorders." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670182.

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32

Dornbach-Bender, Allison. "Facets of Positive Affect and Risk for Bipolar Disorder: Role of the Behavioral Activation System." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1062834/.

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Bipolar disorder is characterized by disruptions in mood and affect that occur not only during mood episodes, but during euthymic periods as well. At the same time, sensitivity of the behavioral activation system (BAS) has been implicated in the disorder and is a risk marker for it. Less clear is the relationship between BAS sensitivity and positive affect, particularly lower level facets of positive affect. The aim of the present study was to examine the relationship between positive affect and vulnerability for mania as assessed using BAS sensitivity. Specifically, the link between daily

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33

Brans, Suzanne. "Applying the social cognitive and sociological models of stigma to student attitudes towards major depression and bipolar disorder." University of Western Australia. School of Psychology, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0041.

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The aims of the current research program were to examine the social-cognitive and sociological models of stigma in relation to student attitudes towards an individual experiencing a mood disorder. Two experiments (Studies 1 and 2) sought to empirically distinguish between controllability and responsibility, both constructs of the attribution model which is subsidiary to the social-cognitive model of stigma. Despite manipulating controllability, participants were reluctant to attribute controllability of cause to individuals experiencing depression or bipolar disorder. The stability of beliefs

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34

Goikolea, Alberdi José Manuel. "Propiedades reguladoras del humor de los antipsicóticos atípicos en los episodios afectivos del trastorno bipolar." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/107704.

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La aparición de los antipsicóticos atípicos o de segunda generación ha supuesto un gran cambio en el manejo de los pacientes con trastorno bipolar. Los ensayos controlados han demostrado la eficacia de prácticamente todos los antipsicóticos atípicos en la manía aguda. Además, la mayor parte de ellos disponen de datos positivos para el tratamiento de mantenimiento del trastorno bipolar, lo que sugiere propiedades normotímicas. E incluso algunos de ellos han mostrado datos positivos en la depresión bipolar. Sin embargo, apenas existen estudios independientes comparando la acción de los atípicos

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35

Pigrau, Santpere Maria Rosa. "Felip V. La seva malaltia i el seu regnat." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/666504.

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Felip V d’Espanya va presentar, des de la joventut, símptomes que avui dia la psiquiatria reconeix com una entitat nosològica específica. La present tesi, interdisciplinària història i medicina, contextualitza en el seu moment històric els episodis més significatius de la malaltia d’aquest rei, alhora que elabora la seva historia psiquiàtrica, a partir de correspondència diplomàtica i altres testimonis coetanis. Es basa en el DSM-5 (Manual Diagnòstic i Estadístic dels Trastorns Mentals, 5th Edició) per emetre un diagnòstic de presumpció del trastorn mental que, de manera inevitable, va condici

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36

Kwan, Hiu-fai, and 關曉暉. "Bipolar affective disorder and schizophrenia with first-episode psychosis : baseline and outcome study in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/192964.

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Objective: The aim of the current study was to investigate the differences in baseline characteristics and three-year outcomes between two diagnostic categories with presentation of first-episode psychosis: bipolar affective disorder (mania with psychotic features) and schizophrenia. The comparison was based on pre-treatment characteristics, clinical presentation, symptomatic and functional outcomes, and engagement in risk behaviours. Methods:461 schizophrenic patients and 54 bipolar affective disorder (BAD) patients between the ages of 15 to 25 years from a local first-episode psychosis tr

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37

Joshua, Nicole R. "Face processing in schizophrenia : an investigation of configural processing and the relationship with facial emotion processing and neurocognition /." Connect to thesis, 2010. http://repository.unimelb.edu.au/10187/7040.

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Cognitive impairment is a key characteristic of schizophrenia and is a clear predictor of functional outcome. This thesis explores the relationship between cognitive ability relating to social and non-social processing. Schizophrenia patients demonstrate an impaired ability to recognise, label and discriminate emotional expression within the face. The underlying mechanisms behind this social cognitive impairment are not yet fully understood. This thesis explores the notion that a basic perceptual impairment in processing facial information adversely impacts on the perception of more comple

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38

Siddaway, Andrew P. "Explaining and predicting psychological problems : the joint importance of positive and negative constructs." Thesis, University of Stirling, 2017. http://hdl.handle.net/1893/26911.

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Positive Clinical Psychology (PCP) argues that positive and negative psychological constructs are jointly important for explaining psychological problems. “Positive” constructs have been explicitly focused on by positive psychology researchers and “negative” constructs have been explicitly focused on by mental health researchers. This thesis examines the relationship between positive and negative constructs in relation to four psychological problems: depressive symptoms (Chapter 2), anxiety-problems (Chapter 3), suicide attempts (SAs) (Chapter 4 and 5), and nonsuicidal self-injury (NSSI) (Chap

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39

Sala, Cassola Regina. "Prevalence, clinical correlates and factors associated with course and outcome of anxiety disorders in youth with bipolar disorders." Doctoral thesis, Universitat de Barcelona, 2011. http://hdl.handle.net/10803/82142.

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OBJECTIVE: Anxiety disorders are among the most common comorbid conditions in youth with bipolar disorder (BP). We aimed to examine the prevalence, correlates, persistence (>50% of the follow-up time), and the onset of new anxiety disorders in youth with comorbid anxiety disorders and BP. METHODS: As part of the Course and Outcome of Bipolar Youth study (COBY), 446 youth ages 7 to 17, who met DSM-IV criteria for BP-I (n=260), BP-II (n=32) or operationalized criteria for BP not otherwise specified (BP-NOS; n=154) were included. Subjects were evaluated for current and lifetime Axis-I psychia

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40

Undurraga, Fourcade Juan Pablo. "Uso de Antidepresivos y Suicidio en el Trastorno Bipolar." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/131130.

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Introducción. El trastorno bipolar (TB) tiene un gran impacto en las personas que lo padecen y una mortalidad por suicidio hasta 20 veces mayor que el resto de la población. La depresión bipolar es uno de los principales factores de riesgo de suicidio, sin embargo existe escasa evidencia en relación a su tratamiento. Uno de los temas más controversiales es el uso de antidepresivos, que a pesar de ser el tratamiento más utilizado, su eficacia y seguridad han sido puestos en duda. Hipótesis. Los pacientes expuestos a AD vs los no expuestos tienen características clínicas y un curso de enferm

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41

Solé, Cabezuelo Brissa. "Alteracions neurocognitives en el trastorn bipolar tipus II: relació amb el funcionament psicosocial i rehabilitació cognitiva." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/380037.

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La recerca en els darrers anys ha demostrat que el pacient amb trastorn bipolar (TB) no està lliure d'afectació neurocognitiva i que aquesta pot tenir una repercussió important en el seu funcionament quotidià. Pel que fa al trastorn bipolar tipus II (TB-II), atès que ha patit una manca d'atenció i durant molt de temps ha estat un subtipus infradiagnosticat, els treballs dirigits a aspectes neuropsicològics han estat escassos amb resultats discrepants i no concloents. Per tant, cal dur a terme estudis centrats en aquesta població específica per tal d'establir de manera adequada el seu perfil ne

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42

Mitjans, Niubó Marina. "Genetic Risk Factors for the Lack of Response to Clinical Treatment in Mental Disorders: an Approach from Pharmacogenetics." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/289981.

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Severe mental disorders, such as Major Depressive Disorder (MDD), Bipolar Disorder (BD) and Schizophrenia (SCZ), represent a huge burden to society, reflecting the limited efficacy of current drug treatments. Although the progress in development of pharmacological treatments is one of the great successes of modern psychiatry, it should not be forgotten that a very high percentage of patients do not receive and/or seek the proper treatment for their disease. Individual differences in clinical response to psychotropic drugs have long been recognized as a fundamental problem in the treatment of t

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43

Schulze, Thomas G., Martin Alda, Mazda Adli, Nirmala Akula, Raffaella Ardau, Elise T. Bui, Caterina Chillotti, et al. "The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134635.

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For more than half a decade, lithium has been successfully used to treat bipolar disorder. Worldwide, it is considered the first-line mood stabilizer. Apart from its proven antimanic and prophylactic effects, considerable evidence also suggests an antisuicidal effect in affective disorders. Lithium is also effectively used to augment antidepressant drugs in the treatment of refractory major depressive episodes and prevent relapses in recurrent unipolar depression. In contrast to many psychiatric drugs, lithium has outlasted various pharmacotherapeutic ‘fashions’, and remains an indispensable e

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44

Jiménez, Martínez Ester. "Marcadores de vulnerabilidad para la conducta suicida en el trastorno bipolar." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/283385.

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Los pacientes bipolares presentan tasas muy elevadas de conductas suicidas. Dado que el litio, uno de los fármacos más ampliamente utilizado para tratar el trastorno bipolar, ha demostrado presentar ciertas propiedades antisuicidas y antiimpulsivas, pretendemos analizar el impacto que la variabilidad genética en algunos de los genes implicados en algunas de las vías relacionadas con el mecanismo de acción del litio ejerce sobre la conducta suicida, así como en los niveles de impulsividad, dimensión considerada tradicionalmente como un potencial endofenotipo de la conducta suicida. Además, habi

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45

Alonso-Lana, Silvia. "El Trastorno Bipolar: Cambios cerebrales asociados con el estado de ánimo y el deterioro cognitivo." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/565911.

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Los estudios de neuroimagen funcional en el trastorno bipolar han descrito un patrón de activación reducida de regiones prefrontales junto con hiperactivación en estructuras subcorticales. Una cuestión que está sin resolver es la determinación de los cambios dependientes del "estado" vs "rasgo", es decir, si existen diferencias entre los episodios maníacos y depresivos, y hasta qué punto los cambios observados persisten en eutimia. Además, los estudios hasta la fecha se han centrado principalmente en el estudio de las activaciones, y poco se sabe acerca de los cambios en la desactivación. Da

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46

Serrano, Serrano Ana Belén. "Rendimiento neurocognitivo y ritmicidad circadiana de pacientes con patologia dual en tratamiento: influencia del trastorno mental comórbido." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/673376.

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El término de Patología Dual (PD) hace referencia a la coexistencia o concurrencia de, al menos, un Trastorno por Uso de Sustancias (TUS) y un Trastorno Mental (TM) en una misma persona. Si bien existe una amplia variedad de combinaciones posibles dada la naturaleza heterogénea de esta condición, en este trabajo se ha considerado la comorbilidad de los TM severos esquizofrenia, trastorno bipolar y depresión mayor. La relevancia de la PD se relaciona con su etiología y expresión fenotípica compleja en la que intervienen múltiples factores de riesgo y de protección junto a su elevada prevalencia

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Paradiso, Krista Michelle. "Manic-Depression in America: Gendered and Narrative Constructions of Mental Health and Illness." The Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=osu1392980305.

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Schulze, Thomas G., Martin Alda, Mazda Adli, Nirmala Akula, Raffaella Ardau, Elise T. Bui, Caterina Chillotti, et al. "The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment." Karger, 2010. https://tud.qucosa.de/id/qucosa%3A27583.

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For more than half a decade, lithium has been successfully used to treat bipolar disorder. Worldwide, it is considered the first-line mood stabilizer. Apart from its proven antimanic and prophylactic effects, considerable evidence also suggests an antisuicidal effect in affective disorders. Lithium is also effectively used to augment antidepressant drugs in the treatment of refractory major depressive episodes and prevent relapses in recurrent unipolar depression. In contrast to many psychiatric drugs, lithium has outlasted various pharmacotherapeutic ‘fashions’, and remains an indispensable e

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Valentí, Ribas Marc. "Estats mixtes, viratges i antidepressius: estudi d'una cohort de pacients bipolars." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/119602.

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El trastorn bipolar és una malaltia crònica i recurrent, caracteritzada per l’aparició d’episodis d´(hipo)mania i/o estats mixtes, que alternen, de manera irregular, amb episodis de depressió. Tot i que l’elevació i expansió de l’estat d’ànim és la principal característica clínica que permet distingir el trastorn bipolar del trastorn depressiu recurrent, és la depressió, més que la mania, la principal causa de discapacitat i mort en els pacients bipolars. A més, els pacients amb trastorn bipolar passen més temps amb simptomatologia depressiva que amb simptomatologia (hipo)maníaca o mixta. D

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Pinacho, Garcia Raquel. "SP Transcription factors in psychotic disorders." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/327025.

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Psychotic disorders including bipolar disorder and schizophrenia are a leading cause of disability across the world but the underlying pathophysiological mechanisms remain poorly understood. Available treatments are inadequate for some sets of symptoms as is the case for negative symptoms in schizophrenia. Alterations in brain connectivity, synaptic plasticity, N-methyl D aspartate receptor (NMDAR) signalling and calcium homeostasis have been suggested to contribute to these disorders. However, the particular transcriptional programmes altered in these disorders are not fully characterised. Pr

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