Bibliografías temáticas / MCD EPOS

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Literatura académica sobre el tema "MCD EPOS"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 8 de febrero de 2022

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Artículos de revistas sobre el tema "MCD EPOS"

1

Heberlein, C., K. D. Fischer, M. Stoffel, et al. "The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation." Molecular and Cellular Biology 12, no. 4 (1992): 1815–26. http://dx.doi.org/10.1128/mcb.12.4.1815.

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The principal regulator of erythropoiesis is the glycoprotein erythropoietin, which interacts with a specific cell surface receptor (EpoR). A study aimed at analyzing EpoR gene regulation has shown that both pluripotent embryonal stem cells and early multipotent hematopoietic cells express EpoR transcripts. Commitment to nonerythroid lineages (e.g., macrophage or lymphocytic) results in the shutdown of EpoR gene expression, whereas commitment to the erythroid lineage is concurrent with or followed by dramatic increases in EpoR transcription. To determine whether gene activity could be correlat
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2

Yoshimura, A., and H. F. Lodish. "In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130." Molecular and Cellular Biology 12, no. 2 (1992): 706–15. http://dx.doi.org/10.1128/mcb.12.2.706.

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The cytoplasmic domain of the cloned erythropoietin (EPO) receptor (EPOR) contains no protein kinase motif, yet addition of EPO to EPO-responsive cells causes an increase in protein-tyrosine phosphorylation. Here we show that addition of EPO or interleukin-3 (IL-3) to an IL-3-dependent cell line expressing the wild-type EPOR causes a small fraction (less than 5%) of total cellular EPOR to shift in gel mobility from 66 to 72 kDa, due at least in part to phosphorylation. Using biotinylated EPO as an affinity reagent, we show that the 72-kDa species is greatly enriched on the cell surface. To dem
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3

Hino, M., A. Tojo, Y. Misawa, H. Morii, F. Takaku, and M. Shibuya. "Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line." Molecular and Cellular Biology 11, no. 11 (1991): 5527–33. http://dx.doi.org/10.1128/mcb.11.11.5527.

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A murine erythroleukemia (MEL) cell line, F5-5, expressed 10,000 binding sites for erythropoietin (EPO) per cell, 10-fold more than was expressed by other murine erythroleukemia cell lines and normal erythroid progenitors. Northern (RNA) and Southern blot analyses revealed overexpression of mRNA for the EPO receptor (EPOR) and rearrangement of one of the EPOR gene alleles in F5-5 cells, respectively. Molecular cloning of F5-5-derived cDNA encoding EPOR revealed that the 5' noncoding region of the EPOR cDNA corresponds to the 3' long terminal repeat sequence of the polycythemic strain of Friend
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4

Youssoufian, H., and H. F. Lodish. "Transcriptional inhibition of the murine erythropoietin receptor gene by an upstream repetitive element." Molecular and Cellular Biology 13, no. 1 (1993): 98–104. http://dx.doi.org/10.1128/mcb.13.1.98.

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Transcription of the murine erythropoietin receptor (EpoR) gene is inhibited by a novel repetitive element that is located upstream of the EpoR promoter. Reporter gene studies reveal that the inhibitory effect is both distance and orientation dependent. This element is a member of a family of repetitive elements specific to rodents and is present at approximately 10(5) copies per mouse genome. It encodes approximately 500- to 900-bp-long transcripts in both erythroid and nonerythroid cells. RNase protection analysis with a probe from the 5' flanking murine EpoR gene reveals that the direction
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5

Heberlein, C., K. D. Fischer, M. Stoffel, et al. "The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation." Molecular and Cellular Biology 12, no. 4 (1992): 1815–26. http://dx.doi.org/10.1128/mcb.12.4.1815-1826.1992.

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The principal regulator of erythropoiesis is the glycoprotein erythropoietin, which interacts with a specific cell surface receptor (EpoR). A study aimed at analyzing EpoR gene regulation has shown that both pluripotent embryonal stem cells and early multipotent hematopoietic cells express EpoR transcripts. Commitment to nonerythroid lineages (e.g., macrophage or lymphocytic) results in the shutdown of EpoR gene expression, whereas commitment to the erythroid lineage is concurrent with or followed by dramatic increases in EpoR transcription. To determine whether gene activity could be correlat
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6

Yoshimura, A., and H. F. Lodish. "In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130." Molecular and Cellular Biology 12, no. 2 (1992): 706–15. http://dx.doi.org/10.1128/mcb.12.2.706-715.1992.

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The cytoplasmic domain of the cloned erythropoietin (EPO) receptor (EPOR) contains no protein kinase motif, yet addition of EPO to EPO-responsive cells causes an increase in protein-tyrosine phosphorylation. Here we show that addition of EPO or interleukin-3 (IL-3) to an IL-3-dependent cell line expressing the wild-type EPOR causes a small fraction (less than 5%) of total cellular EPOR to shift in gel mobility from 66 to 72 kDa, due at least in part to phosphorylation. Using biotinylated EPO as an affinity reagent, we show that the 72-kDa species is greatly enriched on the cell surface. To dem
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7

Yamamura, Yasuko, Hisato Senda, Yukio Kageyama, Tomoko Matsuzaki, Makoto Noda, and Yoji Ikawa. "Erythropoietin and Friend Virus gp55 Activate Different JAK/STAT Pathways through the Erythropoietin Receptor in Erythroid Cells." Molecular and Cellular Biology 18, no. 3 (1998): 1172–80. http://dx.doi.org/10.1128/mcb.18.3.1172.

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ABSTRACT Abnormal erythropoietin (EPO)-independent cell growth is induced after infection of erythroid progenitor cells with a polycythemic strain of Friend virus (FVp). Binding of its Env-related glycoprotein (gp55) to the EPO receptor (EPOR) mimics the activation of the EPOR with EPO. We investigated the gp55-EPOR signaling in erythroblastoid cells from mice infected with FVp and in cells of FVp-induced or gp55-transgenic-mouse-derived erythroleukemia cell lines, comparing it with the EPO-EPOR signaling in EPO-responsive erythroblastoid cells. While the Janus protein tyrosine kinase JAK2 and
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8

Hino, M., A. Tojo, Y. Misawa, H. Morii, F. Takaku, and M. Shibuya. "Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line." Molecular and Cellular Biology 11, no. 11 (1991): 5527–33. http://dx.doi.org/10.1128/mcb.11.11.5527-5533.1991.

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A murine erythroleukemia (MEL) cell line, F5-5, expressed 10,000 binding sites for erythropoietin (EPO) per cell, 10-fold more than was expressed by other murine erythroleukemia cell lines and normal erythroid progenitors. Northern (RNA) and Southern blot analyses revealed overexpression of mRNA for the EPO receptor (EPOR) and rearrangement of one of the EPOR gene alleles in F5-5 cells, respectively. Molecular cloning of F5-5-derived cDNA encoding EPOR revealed that the 5' noncoding region of the EPOR cDNA corresponds to the 3' long terminal repeat sequence of the polycythemic strain of Friend
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9

Youssoufian, H., and H. F. Lodish. "Transcriptional inhibition of the murine erythropoietin receptor gene by an upstream repetitive element." Molecular and Cellular Biology 13, no. 1 (1993): 98–104. http://dx.doi.org/10.1128/mcb.13.1.98-104.1993.

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Transcription of the murine erythropoietin receptor (EpoR) gene is inhibited by a novel repetitive element that is located upstream of the EpoR promoter. Reporter gene studies reveal that the inhibitory effect is both distance and orientation dependent. This element is a member of a family of repetitive elements specific to rodents and is present at approximately 10(5) copies per mouse genome. It encodes approximately 500- to 900-bp-long transcripts in both erythroid and nonerythroid cells. RNase protection analysis with a probe from the 5' flanking murine EpoR gene reveals that the direction
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10

Pelletier, Stéphane, Sébastien Gingras, Megumi Funakoshi-Tago, Sherié Howell, and James N. Ihle. "Two Domains of the Erythropoietin Receptor Are Sufficient for Jak2 Binding/Activation and Function." Molecular and Cellular Biology 26, no. 22 (2006): 8527–38. http://dx.doi.org/10.1128/mcb.01035-06.

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ABSTRACT Biochemical and genetic studies have shown that Jak2 is an essential component of EpoR signal transduction which is required for normal erythropoiesis. However, whether Jak2 is the sole direct mediator of EpoR signal transduction remains controversial. To address this issue, we have used an extensive and systematic mutational analysis across the EpoR cytoplasmic tail and transmembrane domain with the goal of determining whether mutants that negatively affected EpoR biological activity but retained Jak2 activation could be identified. Analysis of over 40 mutant receptors established th
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Tesis sobre el tema "MCD EPOS"

1

Olša, Petr. "Návrh řízení všesměrového mobilního robotu O3-X." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-229210.

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This thesis deals with the design of a three-wheeled omni-directional robot control. The model of control is designed for robot´s omni-directional platform driven by maxon motor with the intelligent positioning controller EPOS. The design of control contains: - installation of the coordinated systems and transformation from one of them into another - design of system´s kinematical model - creation of classes for control and communication with EPOS - creation of the simulative program - planning of the mobile robot´s path - verification that the system is working The solution was based on conti
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2

Knispel, Lukáš. "Pokročilé plánování cesty robotu (RRT)." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230248.

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Tato diplomová práce práce se zabývá plánováním cesty všesměrového mobilního robotu pomocí algoritmu RRT (Rapidly-exploring Random Tree – Rychle rostoucí náhodný strom). Teoretická část popisuje základní algoritmy plánování cesty a prezentuje bližší pohled na RRT a jeho potenciál. Praktická část práce řeší návrh a tvorbu v zásadě multiplatformní C++ aplikace v prostředí Windows 7 za použití aplikačního frameworku Qt 4.8.0, která implementuje pokročilé RRT algoritmy s parametrizovatelným řešičem a speciálním dávkovým režimem. Tento mód slouží k testování efektivnosti nastavení řešiče pro dané ú
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3

Walid, Abdelrahman. "4G LTE : eMBMS with MBSFN Service Simulation using OPNET." Thesis, Mittuniversitetet, Avdelningen för informations- och kommunikationssystem, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-24208.

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Long Term Evolution (LTE) known in the market as 4G LTE, it is an evolution of the GSM/UMTS standard. The overall aim of LTE was to provide a new radio access technology focusing on packet-switched data only. LTE has provided a new peak download rates, low data transfer latencies, and improved the support for mobility. 3Th Generation Partnership Project (3GPP) specialized that LTE released 10 and beyond known as LTE-advanced it is the second evolution of LTE. It has some services such as Coordinated Multipoint Transmission and Reception (CoMP), evolved Multimedia Broadcast and Multicast Servic
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Libros sobre el tema "MCD EPOS"

1

Koutroumanidis, Michalis, and Robin Howard. Encephalopathy, central nervous system infections, and coma. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199688395.003.0032.

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This chapter provides an overview of the indications for and the diagnostic and prognostic value of acute video-electroencephalogram (EEG) and continuous video-EEG monitoring in patients with encephalopathies, encephalitides, and coma. Particular emphasis is placed on the detection of non-convulsive seizures and non-convulsive status epilepticus secondary to acute and sub-acute cerebral insults, including post-cardiac arrest hypoxic-ischaemic brain injury, and on the related pitfalls and uncertainties. It also discusses key technical aspects of the EEG recording, including artefact identificat
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2

Buchner, Helmut. Evoked potentials. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199688395.003.0015.

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Evoked potentials (EPs) occur in the peripheral and the central nervous system. The low amplitude signals are extracted from noise by averaging multiple time epochs time-locked to a sensory stimulus. The mechanisms of generation, the techniques for stimulation and recording are established. Clinical applications provide robust information to various questions. The importance of EPs is to measure precisely the conduction times within the stimulated sensory system. Visual evoked potentials to a pattern reversal checker board stimulus are commonly used to evaluate the optic nerve. Auditory evoked
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3

Wackerhage, Henning, Jonathon Smith, and Darren Wisniewski. Molecular exercise physiology. Edited by Neil Armstrong and Willem van Mechelen. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198757672.003.0031.

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Molecular exercise physiology is the study of exercise physiology using molecular biology methods. The development of differentiated cell types is regulated by transcription factors like the muscle-making MyoD that specifies cell type, while others regulate the development of muscle, tendons, and bones. Maternal nutrition and exercise commonly affect embryonic development through epigenetic mechanisms. Adaptation to exercise involves sensor proteins detecting exercise-related signals, the processing of signals by signalling proteins and networks, and the regulation of the actual adaptations by
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Capítulos de libros sobre el tema "MCD EPOS"

1

Irving, Will. "Case 44." In Oxford Case Histories in Infectious Diseases and Microbiology, edited by Bridget Atkins. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198846482.003.0044.

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Healthcare workers can transmit blood-borne virus (BBV) infections to their patients during the course of performing exposure prone procedures. To reduce the risk of this happening, healthcare workers entering the National Health Service who wish to perform EPPs in the UK must be tested for BBV infection. Hepatitis B- infected healthcare workers may perform EPPs providing they are HBE antigen negative and have a viral load below 200 IU/ml, subject to annual viral load checks. If their viral load is >200 but < 20,000 IU/ml, then they may suppress HBV replication using nucleos(t)ide analogue antiviral therapy, subject to 3-monthly viral load measurement. Healthcare workers known to be currently infected with hepatitis C virus are not allowed to perform EPPs but may do so if they are clear of HCV RNA 12 weeks after antiviral therapy. HIV-infected healthcare workers may perform EPPs if their viral load is suppressed to < 200 copies/ml whilst on combination antiretroviral therapy, subject to 3-monthly monitoring.
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2

Madhra, Mayank, and Andrew W. Horne. "Ectopic pregnancy." In Oxford Textbook of Obstetrics and Gynaecology, edited by Sabaratnam Arulkumaran, William Ledger, Lynette Denny, and Stergios Doumouchtsis. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198766360.003.0039.

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An ectopic pregnancy (EP) occurs when a pregnancy implants outside the uterus. Over 98% implant in the fallopian tube. Non-tubal sites include the interstitium, ovary, cervix, and caesarean section scars. The resultant growth of the EP can damage the implanted tissue, giving rise to pain and intraperitoneal bleeding. The aetiology of EP is uncertain. Risk factors include chlamydial infection, smoking, and assisted reproductive technologies. Many cases occur without identifiable risk factors or typical symptoms, emphasizing the importance of considering the possibility of EP in all women of reproductive age. EPs are diagnosed by a combination of transvaginal ultrasound and serial human chorionic gonadotrophin monitoring. Tubal EPs can be managed effectively and safely by surgical excision (usually via a laparoscopic approach), medical management with intramuscular methotrexate, or expectant management depending upon the size of the EP and the clinical presentation. Non-tubal EPs should be managed on an individual basis.
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3

Croskerry, Pat. "A Tale of Two Cycles." In The Cognitive Autopsy, edited by Pat Croskerry. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190088743.003.0029.

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Two cases are presented here, both involving traumatic injuries resulting from cycle accidents. Significant X-ray findings are missed by the emergency physicians (EPs) but picked up by radiologists in both cases. These are good demonstrations of the common search satisficing error. The first case also demonstrates a significant interference from factors that tend to push decision making into Type 1 processing—cognitive loading, fatigue, and dysphoria. The second case is an example of error due to the EPs’ routine being disrupted by a corridor consultation and authority gradient effects.
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4

"Electrophysiology." In Oxford Handbook of Cardiac Nursing, edited by Kate Olson. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198832447.003.0013.

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This short chapter is intended for cardiac nurses who require a brief introduction to the specialty of cardiac electrophysiology (EP). Further reading and case observation would be required to attain a firm understanding of the technical principles and applications of EP. Much can be learned about the patient’s cardiac rhythm from a resting 12-lead electrocardiogram (ECG) or ambulatory ECG; however, sometimes an EP study (EPS) is required to diagnose the origin and mechanism of an arrhythmia. EPS is used to guide ablation and device or drug treatment. Ablation is an established treatment for supraventricular tachycardias (SVT), and increasingly is used in atrial fibrillation andventricular tachycardia.
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5

Regan, Will, and Jasveer Mangat. "Supraventricular tachycardia." In Challenging Concepts in Congenital and Acquired Heart Disease in the Young. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198759447.003.0008.

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This chapter is a case-based discussion of the management of supraventricular tachycardia (SVT) in children. The case illustrates the challenges of medical management of SVT in neonatal life and infancy, both in terms of acute presentation, as well as longer-term medical care and outpatient monitoring to reduce recurrences of paroxysmal tachycardias as the child grows. Ultimately, the child benefits from an electrophysiology study (EPS) and catheter ablation. The chapter more broadly covers the varying clinical presentations of SVT in children and common treatment strategies employed. The electrophysiological mechanisms of SVT commonly seen in children are outlined. There is a review of the evidence behind the medical management of SVT in children, including a practical guide on the choice of anti-arrhythmic medication for different mechanisms of tachycardia, based on current guidelines. Finally, the chapter summarizes the invasive treatment option of EPS and ablation in children.
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6

Meltzer, Herbert Y., and William V. Bobo. "Antipsychotic and anticholinergic drugs." In New Oxford Textbook of Psychiatry, edited by John R. Geddes, Nancy C. Andreasen, and Guy M. Goodwin. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198713005.003.0064.

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Antipsychotic drugs are utilized for far more than the treatment of psychosis in schizophrenia, their first indication. They now find wide use in a variety of psychotic disorders, mood disorders, developmental disorders, and drug-induced disorders. The classification of drugs as typical or atypical is based on their differences in extra-pyramidal side effects (EPS). This chapter emphasizes the greater diversity, efficacy, and safety of the atypical drugs, and the risk of tardive dyskinesia of the typical drugs. The atypical drug action may produce improvement in cognitive function and negative symptoms, as well as psychosis and mood in some patients. This diversity includes atypical drugs which produce minimal weight gain. Long-acting injectable formulations are recommended for non-adherent patients. The exceptional ability of clozapine to reduce the risk for suicide and to decrease mortality in schizophrenia is discussed. Anticholinergic and other drugs to treat EPS are also discussed.
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7

"Electrophysiology." In Oxford Handbook of Cardiac Nursing, edited by Kate Olson. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199651344.003.0013.

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Electrophysiology (EP) is concerned with electrical problems of the heart. This subspecialty of cardiology focuses on the diagnosis and treatment of arrhythmias. Electrophysiologists could be described as heart electricians. Electrophysiologists treat patients with slow arrhythmias (bradycardia) and fast arrhythmias (tachycardia). This chapter focuses on tachycardia diagnosis and treatment. Some tachycardias are considered simply a nuisance for the patient while others, specifically ventricular tachycardia, can be lethal. The EP study (EPS) is a powerful diagnostic tool at the electrophysiologist’s disposal. This invasive procedure uses catheters and recording systems to pinpoint the cause of a tachycardia which helps direct treatment. This may involve such measures as medications but in many cases can take the form of ablation. Ablation is a curative form of treatment, similar to an EPS, where the cardiac cells causing the tachycardia are destroyed using heat or cold. This short chapter is intended for cardiac nurses who require a brief introduction to the highly complex specialty of cardiac EP.
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8

Davies, Simon. "Peritoneal dialysis." In Oxford Textbook of Medicine. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199204854.003.210702_update_002.

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Abbreviations: CAPD, Continuous ambulatory peritoneal dialysis; APD, automated peritoneal dialysis; CKD Chronic Kidney Disease; AKI, Acute kidney injury; EPS, Encapsulating Peritoneal Sclerosis. Peritoneal dialysis is achieved by repeated cycles of instillation and drainage of dialysis fluid within the peritoneal cavity, with the two main functions of dialysis—solute and fluid removal—occurring due to the contact between dialysis fluid and the capillary circulation of the parietal and visceral peritoneum across the peritoneal membrane. It can be used to provide renal replacement therapy in acute kidney injury or chronic kidney disease....
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9

Meltzer, Herbert Y., and William V. Bobo. "Antipsychotic and anticholinergic drugs." In New Oxford Textbook of Psychiatry. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199696758.003.0155.

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The discovery by Delay and Denicker in 1953 that chlorpromazine was highly effective in alleviating delusions, hallucinations, and disorganized thinking, was the seminal breakthrough in the treatment of schizophrenia, the first agent to produce sufficient relief of core psychotic symptoms to permit life outside of institutions for many patients with schizophrenia, and even a return to a semblance of function within normal limits. Chlorpromazine and the other related typical antipsychotic drugs which were introduced over the next 30 years have proven to be of immense benefit to vast numbers of people who experience psychotic symptoms as a component of a diverse group of neuropsychiatric and medical disorders, as well as drug-induced psychoses. These drugs have been invaluable in providing clues to the aetiology of schizophrenia and other forms of mental illness with psychotic features and as tools in understanding fundamental neural processes, especially those involving dopamine, a key neurotransmitter involved in psychosis. This class of drugs has now been supplanted by the so-called atypical antipsychotic drugs, of which clozapine is the prototype. This chapter will describe the various classes of antipsychotic agents, with emphasis on the atypical antipsychotic drugs, their benefits and adverse effects, recommendations for use in clinical practice, and mechanism of action. The drugs used to treat the extrapyramidal side-effects (EPS) produced mainly by the typical antipsychotic drugs are also considered.
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