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1

Pugazhenthi, Kamali, and n/a. "Melatonin : a new factor in wound healing." University of Otago. Department of Pharmacology & Toxicology, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081208.151313.

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Wound healing is a dynamic process that ultimately leads to restoration of tissue integrity and function. The pineal gland hormone melatonin is known for its anti-oncotic, anti- inflammatory and immuno-modulatory effects. However, its role in wound healing has not been established. Since melatonin is synthesised endogenously, we primarily sought to investigate whether the melatonin receptors played a role in the wound healing process. Using immunohistochemical methods and Western blot analysis we observed that MT₁ was normally absent in the rat skin but was strongly expressed on day 1 to day
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2

游燕珍 and Yin-chun Mabel Yau. "Studies on melatonin receptors in guinea pig platelets and melatonin actions on human leukemic megakaryoblast MEG-01 cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31242613.

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3

Lee, Jack Monroe Jr. "Seasonal Patterns of Melatonin, Cortisol, and Progesterone Secretion in Female Lambs Raised Beneath a 500-kV Transmission Line." PDXScholar, 1992. https://pdxscholar.library.pdx.edu/open_access_etds/1317.

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There is ongoing controversy about the possibility of adverse biological effects from environmental exposures to electric and magnetic fields. These fields are produced by all electrical equipment and appliances including electrical transmission lines. The objective of this environmental science study was to investigate the possible effects of a high voltage transmission line on domestic sheep (Ovis aries L,), a species that can often be found near such lines. The study was primarily designed to determine whether a specific effect of electric and magnetic fields found in laboratory animals als
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4

Lack, Barbara Anne. "Metal interactions with neural substrates and their role in neurodegeneration." Thesis, Rhodes University, 2003. http://hdl.handle.net/10962/d1005709.

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"Life" may be characterized as a controlled stationary flow equilibrium, maintained by energy consuming chemical reactions. The physiological functioning of these life systems include at least 28 of the elements isolated on the periodic table thus far, most of which are metals. However, as with Paracelsus Principle: "The dose makes the poison", there exists a definite link between metal levels, essential and toxic, and the onset of neurodegenerative diseases. The economic costs of brain dysfunction are enormous, but this pales in comparison to the staggering emotional toll on the victims thems
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5

Heuvel, Cameron J. van den. "The role of melatonin in human thermoregulation and sleep /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phv2272.pdf.

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6

Oguine, Adaora. "The effect of food access schedule and diet composition on the rhythmicity of serum melatonin and pineal N-acetyltransferase activity in rats /." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33816.

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Melatonin is a hormone secreted by the pineal gland, which is known to modulate biological rhythms in mammals. This study investigated the effect of food access schedule and dietary composition on serum melatonin and pineal NAT activity in adult male Wistar rats. These rats were maintained on a 12:12 h light:dark schedule with lights on at 0800h. The rats were randomly assigned to two dietary groups. A group was simultaneously fed a protein-rich and carbohydrate-rich granulated diet and the other group fed granulated rat chow. Each dietary group was further divided based on dietary feeding sch
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7

Howard, Christina Marie. "Seasonal and Sex Differences in the Effects of Melatonin on Brain Arginine Vasotocin in Green Treefrogs (Hyla cinerea): Relationship to Melatonin Receptor 1a." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/1871.

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Critical life history events such as breeding, migration and hibernation must take place in the correct environmental context to minimize deleterious consequences on survival and reproductive fitness. Neuroendocrine mechanisms synchronizing internal physiological states with extrinsic environmental cues are vital to timing life history events appropriately. Secretion of the pineal hormone melatonin is sensitive to light and temperature cues, which provides a physiological indicator of time of day and time of year for organisms. Melatonin influences seasonal reproduction in a variety of vertebr
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8

Allen, Andrée Elizabeth. "Indole rhythms, locomotor activity and the environment." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1988. http://hub.hku.hk/bib/B31231482.

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9

Boyd, Clinton Shane. "An investigation into dopamine-melatonin interactions in the rat Corpus striatum and pineal gland: a possible pineal-striatal axis." Thesis, Rhodes University, 2000. http://hdl.handle.net/10962/d1003965.

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Dysfunction of central dopaminergic systems has been implicated in neuroendocrine, neurodegenerative and psychiatric disorders. Monoamine oxidase and catechol-Omethyltransferase represent the key catabolic enzymes of dopamine, terminating neurotransmission following synaptic release of this catecholamine. Thus, both enzymes have been associated with the pathology of dopaminergic systems and represent therapeutic targets elf enormous clinical importance. Some neuroendocrine and circadian effects of melatonin have been attributed to an antidopamimetic effect of this pineal hormone in the hypotha
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10

Earl, Colin R. "The regulation of the timing of melatonin secretion in the sheep." Title page, summary and table of contents only, 1989. http://web4.library.adelaide.edu.au/theses/09PH/09phe12.pdf.

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Includes bibliographical references (leaves 166-195) Addresses the nature of the central mechanisms involved in the regulation of the circadian pattern of secretion of the pineal hormone melatonin in the highly seasonal Suffolk breed of sheep. Provides new information on the behaviour of the onset and offset of melatonin secretion under different photoperiodic conditions.
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11

Kaskar, Rafee'ah. "Effect of melatonin on myocardial susceptibility to ischaemia and reperfusion damage in a rat model of high-fat diet-induced obesity." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/97868.

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Thesis (MScMedSc)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Obesity has reached epidemic proportions worldwide and is currently a serious health problem. It is associated with metabolic abnormalities, oxidative stress, hypertension, insulin resistance and an increased disposition for the development of cardiovascular disease. Elucidation of the pathophysiological mechanisms underlying obesity and its relationship with metabolic and cardiovascular diseases is essential for prevention and management of these disorders. Melatonin, the pineal gland hormone, is a powerful antioxidan
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12

Vanderstraeten, Jacques. "Analyse de l'hypothèse de la perturbation des biorythmes par les champs magnétiques d'extrêmement basse fréquence: mécanismes possibles, impact en santé publique, protocoles de mise a l'épreuve." Doctoral thesis, Universite Libre de Bruxelles, 2013. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209445.

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RESUME GENERAL<p><p>Contexte :une association entre exposition prolongée aux champs magnétiques (CM) d’extrêmement basses fréquences (ELF) et risque sanitaire a été établie pour la leucémie infantile (CM 50/60 Hz de l’électricité, RR = 2,0 pour ≥ 0,4 µT d‘intensité moyennée dans le temps) et est suggérée pour le décès par maladie d’Alzheimer (CM 50/60 Hz, CM 16,7 Hz des voies ferrées pour 21 µT d’intensité moyennée dans le temps) et pour certaines hémopathies chez l’adulte (CM 16,7 Hz). Ces associations restent inexpliquées à ce jour. Sur base d’observations animales (effets des CM ELF sur la
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13

Ajao, Moyosore Salihu. "Effect of exogenous melatonin administration on transient global cerebral ischemia and adult neurogenesis." Thesis, 2012. http://hdl.handle.net/10539/11229.

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Ph.D., Faculty of Science, University of the Witwatersrand, 2011<br>This study investigated the effect of exogenous melatonin administration on transient global cerebral ischemia and adult neurogenesis in adult male Sprague- Dawley rats. It also determined serum melatonin concentrations in all the experimental groups and established any effect of melatonin on estimated total granule cell numbers. Adult male Sprague-Dawley rats were divided into eight groups with each group consisting of 6 rats (n = 6). Post-induction time durations of 72 hours and 7 days was used. Single dose of 5 mg/kg
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14

van, den Heuvel Cameron Jay. "The role of melatonin in human thermoregulation and sleep / by Cameron J. van den Heuvel." Thesis, 1998. http://hdl.handle.net/2440/19237.

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Bibliography: leaves 162-197.<br>vii, 216 leaves : ill. ; 30 cm.<br>To determine the effects of melatonin on sleepiness and body temperature under conditions that better approximated the endogenous melatonin profile.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Obstetrics and Gynaecology, 1998?
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15

Earl, Colin R. "The regulation of the timing of melatonin secretion in the sheep." Thesis, 1989. http://hdl.handle.net/2440/19577.

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Includes bibliographical references (leaves 166-195)<br>xxi, 195 leaves : ill. ; 30 cm.<br>Addresses the nature of the central mechanisms involved in the regulation of the circadian pattern of secretion of the pineal hormone melatonin in the highly seasonal Suffolk breed of sheep. Provides new information on the behaviour of the onset and offset of melatonin secretion under different photoperiodic conditions.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Animal Sciences, 1989
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16

Lutterschmidt, Deborah I. "Chronobiology of garter snakes : environmental and hormonal mechanisms mediating hibernation and reproduction." Thesis, 2006. http://hdl.handle.net/1957/2145.

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Graduation date: 2006<br>Most vertebrates exhibit seasonality in many life history traits. Such seasonal rhythms are temporally organized via the transduction of environmental cues (e.g., photoperiod, temperature) into appropriate endocrine signals. However, among ectothermic vertebrates that undergo continuous winter dormancy, temperature is the only environmental cue available for synchronizing seasonal rhythms. Most intriguing is that in species where reproduction occurs immediately following spring emergence, the associated changes in neurophysiology and behavior that accompany reproduc
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17

McAllan, B. M. (Bronwyn Marie). "The regulation of seasonal reproductive cycles in "Antechinus" : photoperiodic and pineal correlates." 1987. http://web4.library.adelaide.edu.au/theses/09SM/09smm114.pdf.

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18

Beaulieu, Catherine. "Effet de l'histoire lumineuse sur la sensibilité rétinienne et circadienne à la lumière." Thèse, 2009. http://hdl.handle.net/1866/3660.

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L’objectif de ce projet de recherche était de vérifier la présence de changements de sensibilité de la rétine et du système circadien suite à deux semaines d'exposition à un milieu faiblement ou fortement éclairé, dans des conditions contrôlées en laboratoire. De plus, comme un changement de sensibilité peut modifier l'ajustement du système circadien au cycle jour-nuit extérieur, nous voulions également vérifier si la phase circadienne serait modifiée par le traitement et si la vigilance et l’humeur seraient affectées. Dix sujets ont été exposés à de la lumière tamisée (70 lux [LT]) et 10 ont
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