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1

Li, He Ping, Guan Wei Yang, Yun Yan Huang, and Jin Wei Yuan. "Preparation and Characterization of Double Activity Sulfate-Gallate Bagasse Xylan." Advanced Materials Research 842 (November 2013): 216–19. http://dx.doi.org/10.4028/www.scientific.net/amr.842.216.

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The objective of this research was to introduce another kind of anti-biological activitiy group to xylan sulfate for improve performance in anti-biological activitiy. A novel double activity sulfate-gallate bagasse xylan was prepared by using bagasse xylan as raw material, sodium nitrilotriacetic sulfonate and gallic acid as esterifying agents. The structure of product was characterized by FT-IR and SEM. The results show that the bagasse xylan was modified successfully, and the final product is a novel double activity sulfate-gallate bagasse xylan.
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2

Abiha, Gul Bayram, Leyla Bahar, and Semra Utku. "In Vitro Antimicrobial Activities of 6-Substituted-3(2H)- pyridazinone-2-acetyl-2- (substituted/nonsubstitutedbenzal/ acetophenone) Hydrazone Derivatives." Revista Romana de Medicina de Laborator 26, no. 2 (2018): 231–41. http://dx.doi.org/10.2478/rrlm-2018-0017.

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Abstract Aim: In vitro antibacterial activity of 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(substituted/nonsubstitutedbenzal/ acetophenone) hydrazone derivatives were tested in common species causing hospital-acquired infections. Material and Method: Antimicrobial activities of the compounds were performed by determining minimum inhibitory concentration (MIC) value against four Gram-positive, five Gram-negative and four Candida species fungi. Modified serial microdilution method was carried out. Reference strains of American Type Culture Collection (ATCC) were used. Results: In general, elev
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3

Hernández Enríquez, J. M., R. García Alamilla, L. A. García Serrano, and Y. A. Cueto Hernández. "Síntesis, caracterización y actividad fotocatalítica de óxido de titanio modificado con nitrógeno." Boletín de la Sociedad Española de Cerámica y Vidrio 50, no. 5 (2011): 245–52. http://dx.doi.org/10.3989/cyv.322011.

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4

Rabin, Nurun Nahar, Jannatul Morshed, Hashi Akhter та ін. "Surface Modification of the ZnO Nanoparticles with γ-Aminopropyltriethoxysilane and Study of Their Photocatalytic Activity, Optical Properties and Antibacterial Activities". International Journal of Chemical Reactor Engineering 14, № 3 (2016): 785–94. http://dx.doi.org/10.1515/ijcre-2015-0141.

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Abstract Surface modification of Zinc oxide nanoparticles (ZnO) with γ-aminopropyltriethoxy silane (APTES) was investigated. Successful surface modification of the nanoparticles was confirmed experimentally by X-ray Photoelectron Spectroscopy (XPS) and Fourier transform infrared spectroscopy (FT-IR). The effect of the surface modifier concentration on the grafting density and surface area was studied by CHN elemental analysis and Brunauer–Emmett–Teller (BET) analysis. The photocatalytic activity and UV shielding ability of the surface-modified particles prepared in water-ethanol solvent in the
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5

Zuo, Jin Long, Han Qiang Tang, Qian Nie, Biao Li, and Zhi Wei Liu. "Preparation and Characterization of Stearic Acid-Modified Iron-Doped TiO2 Nanoparticles." Advanced Materials Research 777 (September 2013): 47–51. http://dx.doi.org/10.4028/www.scientific.net/amr.777.47.

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In this study, TiO2 nanoparticles composites were prepared by the micro emulsion method, above of all samples were characterized by FT-IR, XRD. Photo activities of Fe-TiO2, TiO2 were evaluated by degradation of oil-bearing wastewater. The results show that the photo activity of Fe-TiO2 was more than that of TiO2; the best presence of iron ion dopants in TiO2 was 0.04%. Used stearic acids as the surface modification agent, Fe-TiO2 were modified by situ surface modification. The results showed that the optimum conditions of stearic acid-Fe - TiO2 :Temperature (20°C), the modified time (45 min),
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6

He, Yu Tang, Tian Gang Yin, Yu Mei Xie, Yong Xia Xu, He Liu, and Tao Ma. "Modification of Zein and its Antioxidant Property In Vitro." Advanced Materials Research 1004-1005 (August 2014): 864–67. http://dx.doi.org/10.4028/www.scientific.net/amr.1004-1005.864.

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Modified zein could improve functional properties of zein broadening its application. The L9(34) orthogonal experimental design was applied to optimize modification technology of zein. The results showed that the optimum parameters of zein modification were using gallic acid as modifier, ethanol 80% and modification time 2.0h. Under these conditions, the fracture elongation of modified zein was reached to 79.5%. The results showed obvious effects. The antioxidant activities of zein were determined by •OH and DPPH radicals scavenging assays. When modified zein concentration was 2.0 g/mL the sca
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7

Rubio, Teresa, Santiago Vernia та Pascual Sanz. "Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity". Molecular Biology of the Cell 24, № 11 (2013): 1801–11. http://dx.doi.org/10.1091/mbc.e12-11-0806.

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AMP-activated protein kinase (AMPK) is a sensor of cellular energy status. It is a heterotrimer composed of a catalytic α and two regulatory subunits (β and γ). AMPK activity is regulated allosterically by AMP and by the phosphorylation of residue Thr-172 within the catalytic domain of the AMPKα subunit by upstream kinases. We present evidence that the AMPKβ2 subunit may be posttranslationally modified by sumoylation. This process is carried out by the E3-small ubiquitin-like modifier (SUMO) ligase protein inhibitor of activated STAT PIASy, which modifies the AMPKβ2 subunit by the attachment o
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8

Wang, Zhiqing, Yana Zhang, Jian Zhang, and Seah H. Lim. "Expression of the CT Antigen, SPAN-Xb, Is Regulated through Promoter Methylation." Blood 104, no. 11 (2004): 4285. http://dx.doi.org/10.1182/blood.v104.11.4285.4285.

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Abstract SPAN-Xb is a spermatid protein that we have recently identified as a novel Cancer-Testis (CT) antigen in hematologic malignancies. We have also shown that SPAN-Xb expression in tumor cell lines could be upregulated by 5-azacytidine, GM-CSF and IL-7. The ability of 5-azacytidine to increase SPAN-Xb expression suggests that SPAN-Xb gene expression, like the other CT antigens, may be regulated through promoter methylation. On the other hand, the ability of GM-CSF and IL-7 to increase SPAN-Xb expression remained to be determined. In this study, we set out to determine whether or not promo
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9

Dolgikh, V. T., L. G. Pyanova, E. V. Naumkina, A. V. Lavrenov, E. V. Matushchenko, and N. V. Kornienko. "Antibacterial Activity of Modified Carbon Sorbents, Prospective for Application." Antibiotics and Chemotherapy 65, no. 7-8 (2020): 3–7. http://dx.doi.org/10.37489/0235-2990-2020-65-7-8-3-7.

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The aim of the work is to study the antibacterial and antimycotic properties of carbon sorbents modified with biologically active substances in relation to pathogens of purulent-inflammatory diseases. Material and methods. The activity of modifier solutions and modified samples of carbon sorbents was studied in relation to test strains of opportunistic microorganisms in comparison with the initial sample of carbon sorbent. A suspension with a known content of microbial cells was prepared from test strains of microorganisms; it was incubated in wells with test samples for 48 hours. The survival
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10

Xia, Yiqing, Yifeng Lin, Qichao Ran, Rongqi Zhu, and Yi Gu. "Modification of benzoxazine with aryl-ether-ether-ketone diphenol: preparation and characterization." RSC Advances 7, no. 3 (2017): 1617–25. http://dx.doi.org/10.1039/c6ra27493e.

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A modified benzoxazine resin system with “high strength, high modulus and high toughness” was prepared by introducing an efficient modifier (m-DHPBP) with high catalytic activity and an aryl-ether-ether-ketone (PEEK) structure.
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11

Varbanets, L. D. "Pseudomonas chlororaphis SUBSP. Aureofaciens native AND MODIFIED BY COMPLEXES OF Ge(IV) AND Sn(IV) LIPOPOLYSACCHARIDE ANTIVIRAL ACTIVITY." Biotechnologia Acta 9, no. 1 (2016): 64–70. http://dx.doi.org/10.15407/biotech9.01.064.

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12

Aliev, A. M., V. Sh Aghayev, A. A. Sarijanov, R. Y. Mirzaeva, and S. R. Mammedova. "ACTIVATION INFLUENCE ON CATALYTIC ACTIVITY OF CATALYSTS, MODIFIED BY METALS CATIONS OF MORDENITE SYNTHETIC ZEOLITE IN TOLUENE DISPROPORTIONATION REACTION." Azerbaijan Chemical Journal, no. 1 (March 19, 2019): 14–18. http://dx.doi.org/10.32737/0005-2531-2019-1-14-18.

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13

Ji, Xiao Ping, Xue Zhang Tan, and Nan Xiang Zheng. "Discussion for Ageing Features of SBS Modified Asphalt and its Assessment Index." Applied Mechanics and Materials 204-208 (October 2012): 1652–58. http://dx.doi.org/10.4028/www.scientific.net/amm.204-208.1652.

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This paper discusses the ageing features of SBS modified asphalt and its assessment index. The performances for both host asphalt and modified asphalt after different RTFOT ageing times was tested and micro analysis was conducted with infrared spectrum. The quantitative analysis for the micro-changes of ageing process was carried out according to Lambert Beer law. The research results show that the longer the ageing time, the smaller the penetration and ductility of asphalt are, and the greater the softening point and viscosity. In comparison with the host asphalt, the absorption peak of SBS m
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14

Liang, Xinhong, Wanli Zhang, Junjian Ran та ін. "Chemical Modification of Sweet Potato β-amylase by Mal-mPEG to Improve Its Enzymatic Characteristics". Molecules 23, № 11 (2018): 2754. http://dx.doi.org/10.3390/molecules23112754.

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The sweet potato β-amylase (SPA) was modified by 6 types of methoxy polyethylene glycol to enhance its specific activity and thermal stability. The aims of the study were to select the optimum modifier, optimize the modification parameters, and further investigate the characterization of the modified SPA. The results showed that methoxy polyethylene glycol maleimide (molecular weight 5000, Mal-mPEG5000) was the optimum modifier of SPA; Under the optimal modification conditions, the specific activity of Mal-mPEG5000-SPA was 24.06% higher than that of the untreated SPA. Mal-mPEG5000-SPA was mono
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15

Wu, Ya Rui, Qiu Ji Chen, and Song Wang. "Synthesis and Activity on Modified TiO2 Coated on Modified Serpentine." Advanced Materials Research 864-867 (December 2013): 743–46. http://dx.doi.org/10.4028/www.scientific.net/amr.864-867.743.

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Synthesis method of modified TiO2coated on modified serpentine was studied. Synthesized compound material was characterized by SEM, EPMA, and XRD etc. Photocatalytic activities of the obtained samples were examined by degrading tests of simulation phenol wastewater and CN-wastewater. Analysis and test results showes that crystal of TiO2/ modified serpentine is anatase, material has good photocatalytic activity and regeneration performance. Also, TiO2/modified serpentine photocatalyst has a very good recycling performance. After ten times recycling the photocatalytic degradation rate has been m
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16

Rejšek, K. "Acid phosphomonoesterase activity in floodplain forest soils." Soil and Water Research 2, No. 2 (2008): 67–75. http://dx.doi.org/10.17221/2116-swr.

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The 4-nitrophenyl phosphate method for acid phosphomonoesterase (EC 3.1.3.2; acid orthophosphoric monoester phosphohydrolase) determination was slightly modified to increase the sensitivity and the stability of the 4-nitrophenol coloured complex in samples rich in humic substances and easily soluble organic compounds. Based on an approach used for mycorrhizal roots, the new analytical protocol was tested on samples taken from a single forest site with a large variation in soil types. Distinctive properties of forest soils and the accuracy/repeatability of the optimised technique were considere
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17

Shen, Bo, Jean-Paul Achkar, Jason T. Connor, et al. "Modified Pouchitis Disease Activity Index." Diseases of the Colon & Rectum 46, no. 6 (2003): 748–53. http://dx.doi.org/10.1007/s10350-004-6652-8.

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18

Chen, Min, Zhen Tian, Qing Xian Yu, and Zhen Feng Gao. "Metallurgical Behavior of Adjusted Converter Slag in Reduction Process." Advanced Materials Research 299-300 (July 2011): 310–13. http://dx.doi.org/10.4028/www.scientific.net/amr.299-300.310.

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The metallurgical behavior of adjusted converter slag components during the selective reduction process were investigated by thermodynamic calculating with different modified slag composition, addition of reducing agent and reduction temperature. The activities of main slag components were drawn from the calculated values. The results showed that the activity of SiO2increased with increment of its mass fraction in slag. The solubility of SiO2increased with increment of temperature. The selective reduction was promoted by selecting the appropriate amount of modifier. Reduction order was elucida
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19

Yang, Ying, Wen-Jun Mao, Huan-Qiu Li, et al. "Synthesis and Biological Evaluation of 7-O-Modified Formononetin Derivatives." Research Letters in Organic Chemistry 2008 (December 18, 2008): 1–4. http://dx.doi.org/10.1155/2008/209830.

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Three series of novel formononetin derivatives were synthesized, in which formononetin and heterocyclic moieties were separated by 2-carbon, 3-carbon, and 4-carbon spacers. The chemical structures of these compounds were confirmed. All the derivatives were screened for antiproliferative activities against Jurkat cell line and HepG-2 cell line. In this paper, compounds prepared were also screened for their antibacterial activity of six bacterial strains. Compound 3b exihibited promising antibacterial activity against B. subtilis with minimal inhibitory concentration (MIC) value of 0.78 μg/mL, a
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20

Bo, Li-Ying, Jia-Nan Pang, Chun-Li Song, and Tie-Jing Li. "Effect of the Plastein Reaction in Presence of Extrinsic Amino Acids on the Protective Activity of Casein Hydrolysate against Ethanol-Induced Damage in HHL-5 Cells." Foods 8, no. 4 (2019): 112. http://dx.doi.org/10.3390/foods8040112.

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Casein hydrolysates (CH) were prepared using papain and modified by the plastein reaction (CH-P) in the presence of extrinsic phenylalanine (CH-P-Phe) or tryptophan (CH-P-Trp). The in vitro protective activity of CH and its modified products against ethanol-induced damage in HHL-5 cells was investigated. The results showed that the modification by the plastein reaction reduced the amino group content of CH. However, the modification by the plastein reaction in the presence of extrinsic amino acids could enhance the antioxidant, proliferative, cell cycle arresting, and anti-apoptosis activity o
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21

Hernáiz, M. J., J. M. Sánchez-Montero, and J. V. Sinisterra. "Influence of the nature of modifier in the enzymatic activity of chemical modified semipurified lipase fromCandida rugosa." Biotechnology and Bioengineering 55, no. 2 (1997): 252–60. http://dx.doi.org/10.1002/(sici)1097-0290(19970720)55:2<252::aid-bit2>3.0.co;2-h.

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22

Mansurov, Z. A., and N. N. Mofa. "Carbon as an Effective Modifier of Silicon Dioxide and Reagent for Obtaining Nanostructurized SHS-Composites." Eurasian Chemico-Technological Journal 14, no. 1 (2011): 31. http://dx.doi.org/10.18321/ectj96.

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The peculiarities of the structure and morphology of quartz particles modified by carbon depending on MCT conditions and type of specific carbonaceous modifier were studied. Powder materials with the composition structure of the materials, which are hybrid formations organics-inorganics with a high chemical activity of its components, were obtained by combined MCT of carbon or carbon containing organic compounds with quartz. A high chemical activity of quartz particles modified by carbon is effectively realized when producing SHS-ceramics composition materials. The rate of redox processes incr
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23

MAEDA, Masatami, Hiroshi UEDA, Masatoshi YAMAZAKI, Masataka OHTSUKA, and Umeyuki DOI. "Biological Response Modifier Activity of Lactococcus lactis 332." YAKUGAKU ZASSHI 118, no. 4 (1998): 150–57. http://dx.doi.org/10.1248/yakushi1947.118.4_150.

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24

Sokolov, A. V., V. A. Kostevich, N. V. Gorbunov, et al. "A LINK BETWEEN ACTIVE MYELOPEROXIDASE AND CHLORINATED CERULOPLASMIN IN BLOOD PLASMA OF PATIENTS WITH CARDIOVASCULAR DISEASES." Medical Immunology (Russia) 20, no. 5 (2018): 699–710. http://dx.doi.org/10.15789/1563-0625-2018-5-699-710.

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Myeloperoxidase is a key factor promoting development of halogenative/oxidative stress under inflammatory conditions. Previously, we have discovered complexes including myeloperoxidase and its physiological inhibitor, ceruloplasmin in blood plasma of patients with inflammatory diseases of different etiology, e.g., atherosclerosis. Studies on regulation of myeloperoxidase activity by ceruloplasmin have shown that hypochlorous acid, a specific product of myeloperoxidase action, is likely to modify ceruloplasmin during inflammation. The present study was aimed for analysis of relationships betwee
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25

Opalski, Adam S., Ilona Grabowska-Jadach, and Slawomir Oszwaldowski. "Biological Activity of Surface Modified Nanocrystals." Current Nanoscience 14, no. 4 (2018): 307–12. http://dx.doi.org/10.2174/1573413714666180215152448.

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26

Yamada, Mayumi, Junzo Nakano, and Hidetaka Taneda. "Antibiotic Activity of Chemically Modified Thiolignin." JAPAN TAPPI JOURNAL 50, no. 12 (1996): 1796–805. http://dx.doi.org/10.2524/jtappij.50.1796.

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27

Muzzarelli, Riccardo A. A., Corrado Muzzarelli, Renato Tarsi, Michele Miliani, Francesca Gabbanelli, and Massimo Cartolari. "Fungistatic Activity of Modified Chitosans againstSaprolegniaparasitica." Biomacromolecules 2, no. 1 (2001): 165–69. http://dx.doi.org/10.1021/bm000091s.

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28

Veverková, Ivana, and Irena Lovětinská-Šlamborová. "Modified Silica Nanofibers with Antibacterial Activity." Journal of Nanomaterials 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/2837197.

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This study is focused on development of functionalized inorganic-organic nanofibrous material with antibacterial activity for wound dressing applications. The nanofibers combining poly(vinyl alcohol) and silica were produced by electrospinning from the sol and thermally stabilized. The PVA/silica nanofibers surface was functionalized by silver and copper nanoparticles to ensure antibacterial activity. It was proven that quantity of adsorbed silver and copper nanoparticles depends on process time of adsorption. According to antibacterial tests results, this novel nanofibrous material shows a bi
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29

Saïhi, D., A. El-Achari, I. Vroman, and A. Périchaud. "Antibacterial activity of modified polyamide fibers." Journal of Applied Polymer Science 98, no. 3 (2005): 997–1000. http://dx.doi.org/10.1002/app.22205.

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30

Lee, Yoon-Suk, Sun Min Park, Hwan Mook Kim, et al. "C5-Modified nucleosides exhibiting anticancer activity." Bioorganic & Medicinal Chemistry Letters 19, no. 16 (2009): 4688–91. http://dx.doi.org/10.1016/j.bmcl.2009.06.072.

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31

Hameed, Abdul, Valentina Gombac, Tiziano Montini, Laura Felisari, and Paolo Fornasiero. "Photocatalytic activity of zinc modified Bi2O3." Chemical Physics Letters 483, no. 4-6 (2009): 254–61. http://dx.doi.org/10.1016/j.cplett.2009.10.087.

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32

Tosi, E., R. Martinet, M. Ortega, H. Lucero, and E. Ré. "Honey diastase activity modified by heating." Food Chemistry 106, no. 3 (2008): 883–87. http://dx.doi.org/10.1016/j.foodchem.2007.04.025.

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33

IYIOLA, ALONGE OLUWASANMI, ABIOLA OLURANTI ADETUNJI, OKEDIJI ADEBUNMI PETER, and ALABI ISMAILA OLANREWAJU. "REMOTELY CONTROLLED CAR SPEED GOVERNOR." Journal of Engineering Studies and Research 26, no. 4 (2021): 53–60. http://dx.doi.org/10.29081/jesr.v26i4.236.

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This study modifies a car speed limiting device with a view to avoiding car over speeding. The speed limiter was modified by incorporating a carrier chip to coordinate the activities of the speed limiter. When the car speed exceeded the designed speed limit, the speed governor came into action and restricted the car from going beyond the pre-set speed by actuating the relay. Warning signal in the form of alarm was activated, and the receiver sent a message to the owner. The study concluded that the modified speed governor design is better, safer and remotely controlled compared to the existing
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34

Cox, A. D., M. M. Hisaka, J. E. Buss, and C. J. Der. "Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein." Molecular and Cellular Biology 12, no. 6 (1992): 2606–15. http://dx.doi.org/10.1128/mcb.12.6.2606.

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While the Ras C-terminal CAAX sequence signals modification by a 15-carbon farnesyl isoprenoid, the majority of isoprenylated proteins in mammalian cells are modified instead by a 20-carbon geranylgeranyl moiety. To determine the structural and functional basis for modification of proteins by a specific isoprenoid group, we have generated chimeric Ras proteins containing C-terminal CAAX sequences (CVLL and CAIL) from geranylgeranyl-modified proteins and a chimeric Krev-1 protein containing the H-Ras C-terminal CAAX sequence (CVLS). Our results demonstrate that both oncogenic Ras transforming a
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35

Cox, A. D., M. M. Hisaka, J. E. Buss, and C. J. Der. "Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein." Molecular and Cellular Biology 12, no. 6 (1992): 2606–15. http://dx.doi.org/10.1128/mcb.12.6.2606-2615.1992.

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While the Ras C-terminal CAAX sequence signals modification by a 15-carbon farnesyl isoprenoid, the majority of isoprenylated proteins in mammalian cells are modified instead by a 20-carbon geranylgeranyl moiety. To determine the structural and functional basis for modification of proteins by a specific isoprenoid group, we have generated chimeric Ras proteins containing C-terminal CAAX sequences (CVLL and CAIL) from geranylgeranyl-modified proteins and a chimeric Krev-1 protein containing the H-Ras C-terminal CAAX sequence (CVLS). Our results demonstrate that both oncogenic Ras transforming a
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36

Almeida, Maria, and José Ribeiro. "Adaptation of the Modified Habitual Physical Activity Questionnaire (Baecke) to the portuguese population." Revista de Enfermagem Referência IV Série, no. 3 (2014): 27–36. http://dx.doi.org/10.12707/riii1303.

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37

Chen, W. C., C. Y. Bao, Y. L. Jeyachandran, et al. "Exploring Antibacterial and Antiadhesive Activities of Titanium Surface Modified with Hydroxyapatite Sol-Gel Containing Silver." Key Engineering Materials 330-332 (February 2007): 653–56. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.653.

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Circumambient tissues infection is a common complication of implanted percutaneous and permucosal devices (PDs). In order to counter the infection, the titanium abutment surface of PDs was modified to achieve antibacterial and antiadhesive activities. Titanium discs were immersed into hydroxyapatite (HA) sol containing different mass fraction silver and thermally treated to get modified discs. The modified discs become more smoother and get crystal HA coatings containing silver. Silver ion release test demonstrate the release rate is very slow and the coating is a reservoir of silver. The anti
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38

Roman, R. L., J. P. Z. Gonçalves, S. C. Fernandes, et al. "Iron Nanoparticles Coated with Nanostructured Carbon: Synthesis and Application in Glucose Biosensors." Materials Science Forum 899 (July 2017): 216–20. http://dx.doi.org/10.4028/www.scientific.net/msf.899.216.

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Nanowires of carbon coated ferric oxide (Fe2O3/C) have been studied to be applied at an electrochemical glucose biosensor as a new type of carbon paste electrode (CPE) modifier. The Fe2O3/C was synthesized by adapting co-precipitation hydrothermal route. Firstly, amperometric sensor based on a modified CPE doped with Fe2O3 has been developed and compared with CPE doped with Fe2O3/C for hydrogen peroxide (H2O2) determination. The performance evaluations for the modified materials and sensors were studied in detail through cyclic voltammetry (CV) method. After, the electrochemical sensor perform
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39

Rabea, E. I., and W. Steurbaut. "Chemically modified chitosans as antimicrobial agents against some plant pathogenic bacteria and fungi." Plant Protection Science 46, No. 4 (2010): 149–58. http://dx.doi.org/10.17221/9/2009-pps.

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The antimicrobial activity of eight chemically modified chitosans against plant pathogenic bacteria of crown gall disease Agrobacterium tumefaciens and soft mould disease Erwinia carotovora and fungi of early blight disease Alternaria alternata, root rot disease Fusarium oxysporum, and damping off disease Pythium debaryanum was investigated. The minimum inhibitory concentration (MIC) of these compounds against the tested bacteria showed that N-(o,o-dichlorobenzyl)chitosan exhibited a high activity against A. tumefaciens and E. carotovora (MIC = 500 and 480 mg/l, respectively). In addition, the
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Folle, Camila, Natalia Díaz-Garrido, Elena Sánchez-López, et al. "Surface-Modified Multifunctional Thymol-Loaded Biodegradable Nanoparticles for Topical Acne Treatment." Pharmaceutics 13, no. 9 (2021): 1501. http://dx.doi.org/10.3390/pharmaceutics13091501.

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The present work is focused on the development of novel surface-functionalized poly(lactic-co-glycolic acid) nanoparticles loaded with thymol (TH-NPs) for topical administration enhancing thymol anti-inflammatory, antioxidant and wound healing activities against acne. TH-NPs were prepared by solvent evaporation method using different surface functionalization strategies and obtaining suitable physicochemical parameters and a good short-term stability at 4 °C. Moreover, TH-NPs skin penetration and antioxidant activity were assessed in ex vivo pig skin models. Skin penetration of TH-NPs followed
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41

Matsui, Kenji, Hiroyuki Shinta, Tadahiko Kajiwara, and Akikazu Hatanaka. "Effect of Modification of Arginine Residues on the Activity of Soybean Lipoxygenase-1." Zeitschrift für Naturforschung C 50, no. 1-2 (1995): 37–44. http://dx.doi.org/10.1515/znc-1995-1-207.

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Abstract Arginine residues of soybean lipoxygenase-1 was modified with an arginine-directed chemical modifier, 2,3-butanedione. Although inactivation was not visible if the enzyme reaction was monitored under the standard assay condition (83.3 μᴍ linoleic acid dispersed in 200 mᴍ sodium borate, pH 9.0), rapid inactivation was observed with 5 mᴍ sodium borate, pH 8.0. The inactivation was protected by the addition of a substrate, linoleic acid, in the modification mixture. Kinetic analyses indicated that one arginine residue accounted for the inactivation. Enzymological analyses showed that the
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42

Kotaja, Noora, Ulla Karvonen, Olli A. Jänne, and Jorma J. Palvimo. "PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases." Molecular and Cellular Biology 22, no. 14 (2002): 5222–34. http://dx.doi.org/10.1128/mcb.22.14.5222-5234.2002.

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ABSTRACT PIAS (protein inhibitor of activated STAT) proteins interact with and modulate the activities of various transcription factors. In this work, we demonstrate that PIAS proteins xα, xβ, 1, and 3 interact with the small ubiquitin-related modifier SUMO-1 and its E2 conjugase, Ubc9, and that PIAS proteins themselves are covalently modified by SUMO-1 (sumoylated). PIAS proteins also tether other sumoylated proteins in a noncovalent fashion. Furthermore, recombinant PIASxα enhances Ubc9-mediated sumoylation of the androgen receptor and c-Jun in vitro. Importantly, PIAS proteins differ in the
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43

Rozhdestvenska, Liudmyla, Kateryna Kudelko, Yevhen Kolomiiets, Yuliya Dzyazko, and Volodymyr Ogenko. "MEMBRANES FUNCTIONALIZED WITH 1d, 2d and 3d CARBON MATERIALS." Ukrainian Chemistry Journal 87, no. 4 (2021): 79–110. http://dx.doi.org/10.33609/2708-129x.87.04.2021.79-110.

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Modification of polymer and ceramic mem­branes by modern one-, two- and three- di­men­sional carbon nanomaterials (carbon nano­tubes, fullerenes and their derivatives, oxi­dized and reduced graphene) is consi­dered. It is shown that carbon materials can be incorporated into membrane matrices both as independent components and as a part of multicomponent modifier. The main methods of modification are the addition of modifiers to the polymer solution with subsequent making of polymer membranes, incorporation of nanoparticles of carbon nanomaterials into the pristine membranes, deposition on the
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44

Qiu, Min, Shuheng Zhai, and Da Liu. "DPP4 Activities Are Associated with Osteopenia/Osteoporosis and Fracture Risk in Newly Diagnosed Type 2 Diabetes." International Journal of Endocrinology 2020 (November 27, 2020): 1–6. http://dx.doi.org/10.1155/2020/8874272.

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Background. Recent studies have shown the beneficial effect of dipeptidyl peptidase-4 (DPP4) inhibitor on bone turnover in diabetes mellitus. However, little clinical evidence for DPP4 activity in newly diagnosed type 2 diabetes is available. This study was designed to investigate the relationship between plasma DPP4 activity and osteoporosis/osteopenia and fracture risk in newly diagnosed type 2 diabetes. Methods. A total of 147 subjects with newly diagnosed type 2 diabetes were enrolled for this cross-sectional study. The bone mineral density (BMD) at the lumbar spine (L1-4) and femoral neck
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45

Kobayashi, Katsunori. "Activity modifies adult brain maturity." Oncotarget 8, no. 29 (2017): 46708–9. http://dx.doi.org/10.18632/oncotarget.18560.

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46

Islam, Tanzila, Catherine Booker, Dmitri Tolkatchev, Su Ha, and Alla S. Kostyukova. "Limited proteolysis of pyranose 2-oxidase results in a stable and active complex." PeerJ Materials Science 2 (May 29, 2020): e7. http://dx.doi.org/10.7717/peerj-matsci.7.

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Glucose oxidating enzymes have a tremendous potential for various energy, healthcare and environmental sensing applications. In this work, we studied the effect of reducing the size of pyranose 2-oxidase (POx) on stability and enzymatic activity of proteolyzed POx. Limited proteolysis of the POx was performed using trypsin to remove flexible structural regions without significant damage to the overall conformation and catalytic activity of the enzyme. Enzymatic activities of the modified and wild-type POx were measured by colorimetric coupled reaction assay and compared. The enzymatic activity
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47

Lu, Yi-hong, Ming-cang Chen, Fang Liu, et al. "Synthesis and Cytotoxic Activity of Novel C-23-Modified Asiatic Acid Derivatives." Molecules 25, no. 16 (2020): 3709. http://dx.doi.org/10.3390/molecules25163709.

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We selectively oxidized the C-23 hydroxyl group in an asiatic acid (AA) derivative and then, for the first time with AA, modification of the C-23 carboxyl group was conducted to synthesize a series of new AA derivatives. The evaluation of their cytotoxic activities against two human cancer cell lines (SKOV-3 and HCT116) using the MTT assay in vitro revealed a distinctive structure activity relationship (SAR) associated with the intramolecular hydrogen bonding of the amide moiety at C-23. According to the established SAR, the cytotoxic activities of four promising compounds were then evaluated
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48

Wang, Zong Hua, Shu Yan Yao, Jian Fei Xia, et al. "Self-Assembled Hybrid Films of Graphene/Carbon Nanotube Modified Electrode for Sensitive and Selective Determination of Rutin." Advanced Materials Research 531 (June 2012): 419–22. http://dx.doi.org/10.4028/www.scientific.net/amr.531.419.

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Abstract: Graphene/Carbon Nanotube hybrid films modified glassy carbon electrode (GN-CNT/GC) was fabricated as electrochemical sensor for the sensitive and rapid determination of rutin. The electrochemical behaviors of rutin at the GN-CNT/GC have been investigated. Rutin can generate a pair of well-defined redox peaks at the GN-CNT/GC located at 0.450 V (Epa) and 0.409 V (Epc). Compared with graphene modified glassy carbon electrode (GN/GC) and carbon nanotube modified glassy carbon electrode (CNT/GC), GN-CNT/GC showed a higher catalytic activity toward rutin. This result indicates that the GN
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49

Shekhovtsova, Svetlana Yur’evna, and Marina Alekseevna Vysotskaya. "Effect of carbon nanotubes on the properties of pmb and asphalt concrete." Vestnik MGSU, no. 11 (November 2015): 110–19. http://dx.doi.org/10.22227/1997-0935.2015.11.110-119.

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In the modern world nanotechnologies are an integral part of successful and progressive development of all the areas of activity. Materials science is not an exception. The authors studied the method of nanomodification and its influence on the performance properties of polymer-modified binder (PMB) and asphalt concrete, produced on their basis. It is established that nanomodified PMB are less susceptible to aging, which is a consequence of the processes of peptization of asphalt-resin complexes (ARC) in the structure of the modified binder and the crosslinking with the polymer matrix. It is r
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50

Sytnik, Svitlana, Yuliia Bilotserkivska, Yuliia Kozeruk, Nataliia Skachedub, Vitalii Lapytskyi, and Oleksandr Mishchenko. "Development of volitional qualities and improvement of psycho-emotional state of higher education students in the process of pentathlon." LAPLAGE EM REVISTA 7, no. 3A (2021): 334–39. http://dx.doi.org/10.24115/s2446-6220202173a1407p.334-339.

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The article conducts research related to the use of higher education technology in the educational process of students of higher education institutions, as research activities in the educational process. The use of research activity is substantiated as a method of activating the cognitive activity of students. Developed and proposed to use modified algorithmic approaches to the organization and content of research activities of students of higher educational institutions.
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