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Artículos de revistas sobre el tema "Newborn infants – Death"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 13 de febrero de 2022

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Cochran-Black, Diana L., Linda D. Cowan, and Barbara R. Neas. "The Relation Between Newborn Hemoglobin F Fractions and Risk Factors for Sudden Infant Death Syndrome." Archives of Pathology & Laboratory Medicine 125, no. 2 (February 1, 2001): 211–17. http://dx.doi.org/10.5858/2001-125-0211-trbnhf.

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Abstract Objectives.—The aims of this study were to determine and compare fetal hemoglobin (HbF) fractions at birth in newborns exposed and not exposed to selected factors that have been reported to increase the risk of sudden infant death syndrome (SIDS). Previous studies have implicated HbF in the etiology of SIDS by finding higher fractions in infants dying from SIDS compared to age-matched control infants. Design.—We performed a cross-sectional study using high-performance liquid chromatography to measure HbF fractions in newborn cord blood samples. Exposure to selected risk factors for SI

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Liamputtong, Pranee. "Childrearing Practices and Child Health among the Hmong in Australia: Implications for Health Services." International Journal of Health Services 32, no. 4 (October 2002): 817–36. http://dx.doi.org/10.2190/ttlq-yc48-gtvq-3djh.

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This study of cultural beliefs and practices related to childrearing and child health among the Hmong in Melbourne, Australia, used in-depth interviews and participant observation of 27 Hmong mothers and some Hmong traditional healers between 1993 and 1998. Traditional Hmong beliefs and practices include: taking notice of the birth date and time, placing a silver necklace on the newborn, not praising the newborn, not taking the infant out during the first 30 days, breastfeeding, the infant's sharing a bed with the parents, and a soul-calling ceremony on the third day after birth. All Hmong mot

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Finster, Mieczyslaw, Margaret Wood, and Srinivasa N. Raja. "The Apgar Score Has Survived the Test of Time." Anesthesiology 102, no. 4 (April 1, 2005): 855–57. http://dx.doi.org/10.1097/00000542-200504000-00022.

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In 1953, Virginia Apgar, M.D. published her proposal for a new method of evaluation of the newborn infant. The avowed purpose of this paper was to establish a simple and clear classification of newborn infants which can be used to compare the results of obstetric practices, types of maternal pain relief and the results of resuscitation. Having considered several objective signs pertaining to the condition of the infant at birth she selected five that could be evaluated and taught to the delivery room personnel without difficulty. These signs were heart rate, respiratory effort, reflex irritabi

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Zhang, Stephanie Q., Hayley Friedman, and Marya L. Strand. "Length of Resuscitation for Severely Depressed Newborns." American Journal of Perinatology 37, no. 09 (June 5, 2019): 933–38. http://dx.doi.org/10.1055/s-0039-1692181.

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Objective Current guidelines for neonatal resuscitation suggest it may be reasonable to stop resuscitation after 10 minutes in infants born with no detectable heartbeat. This study describes the length of resuscitation provided in a cohort of profoundly compromised newborn infants. Study Design Chart review of a regional hospital system database of newborn infants from 2010 to 2017 with a documented 10-minute Apgar score of 0 or 1. Results From a total birth population of 49,876 infants, 172 newborns were identified. Of these, 133 infants did not receive resuscitation and died while receiving

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Zarubin, A. A., E. S. Filippov, A. S. Vanyarkina, O. G. Ivanova, and A. A. Shishkina. "Comparison of Uncontrolled and Device-Induced Therapeutic Hypothermia in Newborn Infants with Hypoxic Ischemic Encephalopathy." Acta Biomedica Scientifica 6, no. 1 (April 10, 2021): 88–93. http://dx.doi.org/10.29413/abs.2021-6.1.13.

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Background. Newborn infants who have undergone severe birth asphyxia have a high risk of neurological disorders and death. The most effective method for the treatment of hypoxic ischemic encephalopathy caused by intrapartum asphyxia is therapeutic hypothermia, or targeted temperature management. Currently, there are no large studies comparing its different methods, therefore the aim of our study was to compare the effectiveness of device-induced and uncontrolled therapeutic hypothermia in newborn infants who underwent intrapartum asphyxia.Materials and methods. Study design: we conducted a ret

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Putra, Putu Junara. "Characteristics and outcomes of low birth weight infants in Bali." Paediatrica Indonesiana 52, no. 5 (October 31, 2012): 300. http://dx.doi.org/10.14238/pi52.5.2012.300-3.

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Background The prevalence and the mortality of low birthweight infants are still high. Low birth weight (LBW) births areresponsible for newborn death. LBW infants are easier to sufferserious health problems and death. Lower infant body weightand younger gestational age are determinants of greater risk ofmortality.Objective To determine the characteristics of LBW infants andtheir outcomes in Sanglah Hospital, Denpasar.Methods This prospective study was conducted on all LBWinfants in the nursery from their time of admission until dischargefor the year of 20 11..Results There were 120 LBW infants

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Raha-Chowdhury, R., C. A. Moore, D. Bradley, R. Henley, and M. Worwood. "Blood ferritin concentrations in newborn infants and the sudden infant death syndrome." Journal of Clinical Pathology 49, no. 2 (February 1, 1996): 168–70. http://dx.doi.org/10.1136/jcp.49.2.168.

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Breathnach, Ciara, and Eunan O’Halpin. "Registered ‘unknown’ infant fatalities in Ireland, 1916–32: gender and power." Irish Historical Studies 38, no. 149 (May 2012): 70–88. http://dx.doi.org/10.1017/s0021121400000638.

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The phenomenon of ‘unknown’ infant deaths addressed in this article was first explored in the course of research on fatalities arising from political violence during the Irish revolution of 1916–1921. Our data are derived from the General Register of Death Indices (G.R.D.I.), held in the General Register Office, Dublin, which are organised alphabetically, and which form an official record of deaths registered either by relatives of the deceased or by medical personnel. When infant ‘unknown’ fatalities were extracted to form a discrete database they showed a curious gender disparity. There were

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Chaves, Luciano Eustáquio, and Luiz Fernando C. Nascimento. "Estimating outcomes in newborn infants using fuzzy logic." Revista Paulista de Pediatria 32, no. 2 (June 2014): 164–70. http://dx.doi.org/10.1590/0103-058220143228413.

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OBJECTIVE: To build a linguistic model using the properties of fuzzy logic to estimate the risk of death of neonates admitted to a Neonatal Intensive Care Unit.METHODS: Computational model using fuzzy logic. The input variables of the model were birth weight, gestational age, 5th-minute Apgar score and inspired fraction of oxygen in newborn infants admitted to a Neonatal Intensive Care Unit of Taubaté, Southeast Brazil. The output variable was the risk of death, estimated as a percentage. Three membership functions related to birth weight, gestational age and 5th-minute Apgar score were built,

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Chace, Donald H., James C. DiPerna, Brenda L. Mitchell, Bethany Sgroi, Lindsay F. Hofman, and Edwin W. Naylor. "Electrospray Tandem Mass Spectrometry for Analysis of Acylcarnitines in Dried Postmortem Blood Specimens Collected at Autopsy from Infants with Unexplained Cause of Death." Clinical Chemistry 47, no. 7 (July 1, 2001): 1166–82. http://dx.doi.org/10.1093/clinchem/47.7.1166.

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Abstract Background: Deaths from inherited metabolic disorders may remain undiagnosed after postmortem examination and may be classified as sudden infant death syndrome. Tandem mass spectrometry (MS/MS) may reveal disorders of fatty acid oxidation in deaths of previously unknown cause. Methods: We obtained filter-paper blood from 7058 infants from United States and Canadian Medical Examiners. Acylcarnitine and amino acid profiles were obtained by MS/MS. Specialized interpretation was used to evaluate profiles for disorders of fatty acid, organic acid, and amino acid metabolism. The analyses of

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Wang, Raymond Y. "A Newborn Screening, Presymptomatically Identified Infant With Late-Onset Pompe Disease: Case Report, Parental Experience, and Recommendations." International Journal of Neonatal Screening 6, no. 1 (March 14, 2020): 22. http://dx.doi.org/10.3390/ijns6010022.

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Pompe disease is an inherited lysosomal storage disorder caused by acid alpha-glucosidase (GAA) enzyme deficiency, resulting in muscle and neuron intralysosomal glycogen storage. Clinical symptoms vary from the severe, infantile-onset form with hypertrophic cardiomyopathy, gross motor delay, and early death from respiratory insufficiency; to a late-onset form with variable onset of proximal muscle weakness and progressive respiratory insufficiency. Newborn screening programs have been instituted to presymptomatically identify neonates with infantile-onset Pompe disease for early initiation of

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S., Srinivasa, Anjum Aara C. A., and Pavan Kumar Kalla. "Postnatal foot length of newborn: its correlation with gestational maturity." International Journal of Contemporary Pediatrics 7, no. 7 (June 24, 2020): 1614. http://dx.doi.org/10.18203/2349-3291.ijcp20202626.

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Background: Neonatal death is one of the major contributors (50%) of Under-five child mortality and 70% of the infant mortality. The main causes of neonatal deaths are prematurity and low birth weight (LBW). This study was undertaken to assess newborn foot length and determine its usefulness in identifying LBW/Preterm Babies.Methods: This is a cross sectional hospital based study of 173 newborn babies, done in KIMS Hospital, Bengaluru. All live newborn infants were included in the study. Newborn babies with lower limb congenital anomalies were excluded from the study.Results: Out of 173 newbor

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Yeh, Jennifer, Natasha K. Stout, Aeysha Chaudhry, Michael Gooch, Pamela McMahon, Kurt D. Christensen, Lisa Diller, and Ann C. Wu. "Population-based cancer predisposition testing as a component of newborn screening: A cost-effectiveness analysis." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 10021. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.10021.

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10021 Background: The role of population-based newborn genetic testing to identify infants at high risk of childhood-onset cancers has not been studied, despite the availability of cancer surveillance guidelines for early detection in high-risk infants and children. Methods: We developed the Precision Medicine Prevention and Treatment (PreEMPT) Model to estimate the value of targeted population-based newborn genomic sequencing (tNBS) for a select panel of genes associated with early onset pediatric malignancy. Cohorts of US newborns were simulated under tNBS screening vs. usual care, from birt

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Parti, Sumiati Malik, and Nurhayati. "Pengaruh Perawatan Metode Kanguru (PMK) terhadap Pencegahan Hipotermi pada Bayi Baru Lahir." Jurnal Bidan Cerdas 2, no. 2 (May 27, 2020): 66–71. http://dx.doi.org/10.33860/jbc.v2i2.56.

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Most causes of infant death are problems that occur in newborn/neonatal (0-28 days old), Low Birth Weight Babies (LBW) is one of the factors which has a contribution to infant mortality, especially in the neonatal period. Infant Mortality Rate (IMR) is a benchmark in determining the degree of public health, both at the National and Provincial levels. This study aimed to determine the effect of the Kangaroo Mother Care Method (KMC) on the prevention of hypothermia in low birth weight infants at Morowali District Hospital in 2019. The type of research used was a quasi-experiment. The population

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Bahtera, Tjipta, Santoso Suroso, and Bambang Darmanto. "Neurological Sequalae in Survivors of Perinatal Asphyxia." Paediatrica Indonesiana 32, no. 7-8 (January 30, 2019): 169–77. http://dx.doi.org/10.14238/pi32.7-8.1992.169-77.

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Perinatal asphyxia is the most common cause of either death or severely handicapped survivors. Perinatal asphyxia can be identified by one, five, ten minutes APGAR scores less than 7. Prolonged asphyxia produce hypoxemia, acidosis, hypercapnia, thus diminishing cerebral blood flow, which in turn results in clinical patterns of Hypoxic - Ischemic Encephalopathy (HIE). The atm of this study was to evaluate the accuracy of clinical observation on newborn asphyxia to predict the presence of neurological deficits connected with blood gas analysts investigation. Thirty eight newborn babies who bad A

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Deguen, Séverine, Guadalupe Perez Marchetta, and Wahida Kihal-Talantikite. "Measuring Burden of Disease Attributable to Air Pollution Due to Preterm Birth Complications and Infant Death in Paris Using Disability-Adjusted Life Years (DALYs)." International Journal of Environmental Research and Public Health 17, no. 21 (October 26, 2020): 7841. http://dx.doi.org/10.3390/ijerph17217841.

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Several studies have found maternal exposure to particulate matter pollution was associated with adverse birth outcomes, including infant mortality and preterm birth. In this context, our study aims to quantify the air pollution burden of disease due to preterm birth complications and infant death in Paris, with particular attention to people living in the most deprived census blocks. Data on infant death and preterm birth was available from the birth and death certificates. The postal address of mother’s newborn was converted in census block number. A socioeconomic deprivation index was built

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Ebela, Inguna, Irisa Zile, Aleksandrs Zakis, Valdis Folkmanis, and Ingrida Rumba-Rozenfelde. "Mortality of Children Under Five and Prevalence of Newborn Congenital Anomalies in Relation to Macroeconomic and Socioeconomic Factors in Latvia." Medicina 47, no. 12 (January 3, 2012): 98. http://dx.doi.org/10.3390/medicina47120098.

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Background. Mortality of infants and children younger than 5 years is a globally recognized and broad national welfare indicator. Scientific literature has data on the correlation of mortality indicators with macroeconomic indicators. It is important to study the associations between prevalence and mortality indicators and socioeconomic factors, since deaths from congenital anomalies account for approximately 25%–30% of all deaths in infancy. The aim of the study was to analyze the overall trend in mortality of infants and young children aged 0 to 4 years in relation to macroeconomic factors i

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Perrone, Serafina, Chiara Lembo, Sabrina Moretti, Giovanni Prezioso, Giuseppe Buonocore, Giorgia Toscani, Francesca Marinelli, Francesco Nonnis-Marzano, and Susanna Esposito. "Sudden Infant Death Syndrome: Beyond Risk Factors." Life 11, no. 3 (February 26, 2021): 184. http://dx.doi.org/10.3390/life11030184.

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Sudden infant death syndrome (SIDS) is defined as “the sudden death of an infant under 1 year of age which remains unexplained after thorough investigation including a complete autopsy, death scene investigation, and detailed clinical and pathological review”. A significant decrease of SIDS deaths occurred in the last decades in most countries after the beginning of national campaigns, mainly as a consequence of the implementation of risk reduction action mostly concentrating on the improvement of sleep conditions. Nevertheless, infant mortality from SIDS still remains unacceptably high. There

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Nuryanti Zulala, Nuli, Mei Neni Sitaresmi, and Sulistyaningsih. "INISIASI MENYUSU DINI MENJAGA KESTABILAN SUHU PADA BAYI BARU LAHIR." MEDIA ILMU KESEHATAN 7, no. 1 (November 17, 2019): 51–59. http://dx.doi.org/10.30989/mik.v7i1.222.

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Background: Hypothermia contributes 6.3% to neonatal mortality. Interventions to keep newborns warm can reduce neonatal mortality by 18-42%. Early Breastfeeding Initiation (EBI) is a simple intervention that reduces the risk of neonatal death. Objective: The aim of this study to determine the difference of axillary temperature of newborn between improper EBI group and proper EBI group for 24 hours. Methods: This prospective cohort study was conducted at Aisyiyah Muntilan Hospital. Sixty-two healthy newborns from healthy mothers born in November 2016 who meet the inclusion and exclu

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Akhmina, N. I., A. V. Nikopol’skaya, E. M. Bragina, O. N. Zhdanova, and Zh L. Chabaidze. "Anhidrotic ectodermal dysplasia in a newborn: case history." Russian Journal of Woman and Child Health 3, no. 4 (2020): 340–43. http://dx.doi.org/10.32364/2618-8430-2020-3-4-340-343.

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The article describes step-by-step diagnostic approach for identifying the cause of fever in a newborn: from excluding infections and noninfectious factors provoking impaired thermoregulation to the diagnosis of a rare congenital disorder, anhidrotic ectodermal dysplasia (EDA) confirmed by genetic testing. EDA is a hereditary condition caused by mutations in the EDA gene encoding prenatal development of ectodermal derivatives. The main phenotypic signs of EDA are aplasia (hypoplasia) of sweat glands, dysplasia of skin and its appendages (hypotrichosis, nail hypoplasia etc.), and hypodontia. Hy

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Zulala, Nuli Nuryanti, Mei Neni Sitaresmi, and Sulistyaningsih Sulistyaningsih. "INISIASI MENYUSU DINI MENJAGA KESTABILAN SUHU PADA BAYI BARU LAHIR." Media Ilmu Kesehatan 7, no. 1 (April 30, 2018): 51–59. http://dx.doi.org/10.30989/mik.v7i1.267.

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Background: Hypothermia contributes 6.3% to neonatal mortality. Interventions to keep newborns warm can reduce neonatal mortality by 18-42%. Early Breastfeeding Initiation (EBI) is a simple intervention that reduces the risk of neonatal death. Objective: The aim of this study to determine the difference of axillary temperature of newborn between improper EBI group and proper EBI group for 24 hours. Methods: This prospective cohort study was conducted at Aisyiyah Muntilan Hospital. Sixty-two healthy newborns from healthy mothers born in November 2016 who meet the inclusion and exclu

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Krebs, Vera Lúcia Jornada, and Gleise Aparecida Moraes Costa. "Clinical outcome of neonatal bacterial meningitis according to birth weight." Arquivos de Neuro-Psiquiatria 65, no. 4b (December 2007): 1149–53. http://dx.doi.org/10.1590/s0004-282x2007000700011.

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OBJECTIVE: To describe the clinical outcome and the complications of bacterial meningitis according to birth weight of out born neonates admitted in intensive care unit during an 11 year-period. METHOD: Eighty-seven newborns were studied. Thirty-four infants were low birth weight newborn and 53 presented birth weight > " 2500 g. The clinical data were obtained through the analysis of patients’ files. Fisher’s exact test, the c² and the Mann-Whitney test were applied. RESULTS: Neurological symptoms were more common in infants weighed > " 2500 g (p<0.05). Complications affected half of

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Kaku, Noriyuki, Kenji Ihara, Yuichiro Hirata, Kenji Yamada, Sooyoung Lee, Hikaru Kanemasa, Yoshitomo Motomura, et al. "Diagnostic potential of stored dried blood spots for inborn errors of metabolism: a metabolic autopsy of medium-chain acyl-CoA dehydrogenase deficiency." Journal of Clinical Pathology 71, no. 10 (May 2, 2018): 885–89. http://dx.doi.org/10.1136/jclinpath-2017-204962.

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AimIt is estimated that 1–5% of sudden infant death syndrome (SIDS) cases might be caused by undiagnosed inborn errors of metabolism (IEMs); however, the postmortem identification of IEMs remains difficult. This study aimed to evaluate the usefulness of dried blood spots (DBSs) stored after newborn screening tests as a metabolic autopsy to determine the causes of death in infants and children who died suddenly and unexpectedly.MethodsInfants or toddlers who had suddenly died without a definite diagnosis between July 2008 and December 2012 at Kyushu University Hospital in Japan were enrolled in

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Klyukhina, Yuliya Borisovna, Lyudmila Aleksandrovna Zhelenina, and Dmitriy Olegovich Ivanov. "Pulmonary Catamnesis in Children on Artificial Lung Ventilation in the Neonatal Period." Pediatrician (St. Petersburg) 5, no. 3 (September 15, 2014): 16–21. http://dx.doi.org/10.17816/ped5316-21.

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Bronchopulmonary pathology is the most frequent cause of morbidity and mortality among newborn infants. Emergency aid and inten-sive care to newborn infants decrease death rate among children; at the same time, they cause an increase in pulmonary morbidity. The article deals with data concerning generation of bronchopulmonary diseases in children who underwent resuscitation in neonatal period, tracks pulmonary catamnesis, and analyzes hereditary load. The article confirms the adverse effect of artificial lung ventilation on lungs of both mature and premature babies. Neonatal pneumonia, togethe

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Skene, Loane. "Legal Issues in Treating Critically Ill Newborn Infants." Cambridge Quarterly of Healthcare Ethics 2, no. 3 (1993): 295–308. http://dx.doi.org/10.1017/s0963180100004308.

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Say an infant is born with high lesion spina bifida. She is paralyzed from the waist down and has severe wasting of all areas below the waist. She will always be doubly incontinent and will have no normal sexual function. She has hydrocephalus and a brain stem, abnormality (Arnold Chiari malformation) that is likely to significantly shorten her life. She will probably be retarded and epileptic. She has severe leg deformities — dislocated hips, dislocated knees, and club feet. Her hips are held in a constant position over her chest and her knees cannot be bent in the right direction. She has an

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Carrier, Jessica, and Vivian Haughton. "Congenital Syphilis: A Challenging Case for NICU Clinicians." Neonatal Network 38, no. 3 (May 1, 2019): 170–77. http://dx.doi.org/10.1891/0730-0832.38.3.170.

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Congenital syphilis (CS) has been consistently on the rise in the United States since 2012, despite long-standing recommendations for routine testing and treatment of pregnant women. CS is associated with miscarriage, stillbirth, early infant death, and organ dysfunction in the newborn. Prevention is the optimal goal; however, early identification of infected infants is imperative to reduce the risk of serious, long-term complications. Clinicians must possess adequate knowledge of CS and the potentially life-threatening conditions that can arise to provide immediate and effective care. This ca

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Kommawar, Ankush, Rajendra Borkar, Jayant Vagha, Bhavana Lakhkar, Rewat Meshram, and Amar Taksandae. "Study of respiratory distress in newborn." International Journal of Contemporary Pediatrics 4, no. 2 (February 22, 2017): 490. http://dx.doi.org/10.18203/2349-3291.ijcp20170695.

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Background: Respiratory distress is one of the most common reasons an infant is admitted to the neonatal intensive care unit. Fifteen percent of term infants and 29% of late preterm infants admitted to the neonatal intensive care unit develop signiﬁcant respiratory morbidity; this is even higher for infants born before 34 weeks ‘gestation. Certain risk factors increase the likelihood of neonatal respiratory disease. These factors include prematurity, meconium-stained amniotic ﬂuid (MSAF), caesarean section delivery, gestational diabetes, maternal chorioamnionitis, or prenatal ultrasonographic

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Pols, T., L. S. de Vries, A. Salamon, P. G. J. Nikkels, K. D. Lichtenbelt, S. M. Mulder-de Tollenaer, and G. van Wezel-Meijler. "Symmetrical Thalamic Lesions in the Newborn: A Case Series." Neuropediatrics 50, no. 03 (March 26, 2019): 152–59. http://dx.doi.org/10.1055/s-0039-1683864.

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AbstractAlthough bilateral injury to the thalami is often seen in (near)term infants with hypoxic ischemic encephalopathy (HIE), symmetrical thalamic lesions (STL) is a different, very rare condition, seen both in full-term and preterm infants often after an antenatal insult, although the history is not always clear. These lesions are usually first detected using cranial ultrasound (cUS). They may not always be seen on the first (admission) scan, but become apparent in the course of the 1st week after birth. Clinically, these infants present with hypo- or hypertonia, absence of sucking and swa

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Ortigosa Rocha, Cristiane, Roberto Eduardo Bittar, and Marcelo Zugaib. "Neonatal Outcomes of Late-Preterm Birth Associated or Not with Intrauterine Growth Restriction." Obstetrics and Gynecology International 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/231842.

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Objective. To compare neonatal morbidity and mortality between late-preterm intrauterine growth-restricted (IUGR) and appropriate-for-gestational-age (AGA) infants of the comparable gestational ages (GAs).Methods. We retrospectively analyzed neonatal morbidity and mortality of 50 singleton pregnancies involving fetuses with IUGR delivered between 34 and 36 6/7 weeks of GA due to maternal and/or fetal indication. The control group consisted of 36 singleton pregnancies with spontaneous preterm delivery at the same GA, in which the infant was AGA. Categorical data were compared between IUGR and A

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Delaney, Meghan, and Dana C. Matthews. "Hemolytic disease of the fetus and newborn: managing the mother, fetus, and newborn." Hematology 2015, no. 1 (December 5, 2015): 146–51. http://dx.doi.org/10.1182/asheducation-2015.1.146.

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AbstractHemolytic disease of the fetus and newborn (HDFN) affects 3/100 000 to 80/100 000 patients per year. It is due to maternal blood group antibodies that cause fetal red cell destruction and in some cases, marrow suppression. This process leads to fetal anemia, and in severe cases can progress to edema, ascites, heart failure, and death. Infants affected with HDFN can have hyperbilirubinemia in the acute phase and hyporegenerative anemia for weeks to months after birth. The diagnosis and management of pregnant women with HDFN is based on laboratory and radiographic monitoring. Fetuses wit

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Gong, Alice, Judith Livingston, Liza Creel, Elena Ocampo, Tiffany McKee-Garrett, and Charleta Guillory. "Texas Pulse Oximetry Project: A Multicenter Educational and Quality Improvement Project for Implementation of Critical Congenital Heart Disease Screening Using Pulse Oximetry." American Journal of Perinatology 34, no. 09 (March 6, 2017): 856–60. http://dx.doi.org/10.1055/s-0037-1599214.

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Objective Critical congenital heart disease (CCHD) is a leading cause of death in infants. Newborn screening (NBS) by pulse oximetry allows early identification of CCHD in asymptomatic newborns. To improve readiness of hospital neonatal birthing facilities for mandatory screening in Texas, an educational and quality improvement (QI) project was piloted to identify an implementation strategy for CCHD NBS in a range of birthing hospitals. Study Design Thirteen Texas hospitals implemented standardized CCHD screening by pulse oximetry. An educational program was devised and a tool kit was created

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Muramatsu, Hideki, Daiei Kojima, Yusuke Okuno, Shinsuke Kataoka, Yoko Nakajima, Tetsuya Ito, Ikuya Tsuge, et al. "Combination of TREC Measurement and Next-Generation Sequencing in Newborn Screening for Severe Combined Immunodeficiency: A Pilot Program in Japan." Blood 132, Supplement 1 (November 29, 2018): 3717. http://dx.doi.org/10.1182/blood-2018-99-118261.

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Abstract INTRODUCTION Severe combined immunodeficiency disease (SCID) is the most severe form of primary immunodeficiency disorders (PIDs). Impaired cellular and humoral immunity renders the affected infants susceptible to various infections and results in death within the first 2 years of life. Affected infants are asymptomatic at birth, untreated disease leads to death, and prompt treatment (i.e., hematopoietic stem cell transplantation, gene therapy, or enzyme replacement therapy) is linked to significant improvement in outcome. Thus, SCID meets the disease criteria for newborn screening (N

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Rodrigues, Larissa, Daniela Danttas Lima, Juliana Vasconcelos Freitas de Jesus, Gabriel Lavorato Neto, Egberto Ribeiro Turato, and Claudinei José Gomes Campos. "Understanding bereavement experiences of mothers facing the loss of newborn infants." Revista Brasileira de Saúde Materno Infantil 20, no. 1 (March 2020): 65–72. http://dx.doi.org/10.1590/1806-93042020000100005.

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Abstract Objective: to understand mothers' bereavement experiences regarding the loss of their newborn child in the Neonatal Intensive Care Unit of a Brazilian university hospital. Methods: the study was designed by the clinical-qualitative method to understand the meaning of the emerging relationships of health scenarios. Sample consisted of six mothers. The sufficiency of the sample was verified through the saturation of the data. The data collection instrument was a semistructured interview with script of open questions, the collected material was recorded and transcribed in full. Thematic

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Serdarevich, Christine, and James E. Fewell. "Influence of core temperature on autoresuscitation during repeated exposure to hypoxia in normal rat pups." Journal of Applied Physiology 87, no. 4 (October 1, 1999): 1346–53. http://dx.doi.org/10.1152/jappl.1999.87.4.1346.

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Failure to autoresuscitate by hypoxic gasping during prolonged sleep apnea has been suggested to play a role in sudden infant death. Furthermore, thermal stress brought about by a contribution of infection, overwrapping, or excessive environmental heating has been shown to be associated with an increased risk of sudden infant death, particularly in prone sleeping infants. The present experiments were carried out on newborn rat pups to investigate the influence of “forced” changes in core temperature on their time to last gasp during a single hypoxic exposure and on their ability to autoresusci

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Kooi, E. MW. "Current insights in brain protection for the sick newborn infant." Pediatrician (St. Petersburg) 6, no. 1 (March 15, 2015): 22–28. http://dx.doi.org/10.17816/ped6122-28.

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This paper presents an overview of the modern antenatal and postnatal strategies in brain protection for both preterm and term born infants. It is known, that the two most common causes of neonatal brain injury are prematurity and hypoxic-ischemic encephalopathy (HIE) in the term born infant. Approximately one in nine babies is born before term. Nowadays these preterm born infants more often survive the neonatal period due to developments in treatment options in the last decades. They are however at a high risk for developing brain damage and neurodevelopmental impairment later in life. Approx

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Pratiwi, I. G. A. P. Eka, Soetjiningsih Soetjiningsih, and I. Made Kardana. "Effect of kangaroo method on the risk of hypothermia and duration of birth weight regain in low birth weight infants: A randomized controlled trial." Paediatrica Indonesiana 49, no. 5 (October 31, 2009): 253. http://dx.doi.org/10.14238/pi49.5.2009.253-8.

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Background In Indonesia, the infant mortality rate in 2001 was 50 per 1000 live births, with 34.7% due to perinatal death. This perinatal death was associated with low birth weight (LBW) newborn, which was caused by prematurity, infection, birth asphyxia, hypothermia, and inadequate breast feeding. In developing countries, lack of facilities of LBW infant care leads to the utilization of kangaroo method as care to prevent hypothermia in LBW newborn.Objective To evaluate the differences of hypothermia event andduration of birth weight regain in LBW newborns between earlykangaroo care (EKC) and

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Kumar, Praveen. "Universal Pulse Oximetry Screening for Early Detection of Critical Congenital Heart Disease." Clinical Medicine Insights: Pediatrics 10 (January 2016): CMPed.S33086. http://dx.doi.org/10.4137/cmped.s33086.

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Critical congenital heart disease (CCHD) is a major cause of infant death and morbidity worldwide. An early diagnosis and timely intervention can significantly reduce the likelihood of an adverse outcome. However, studies from the United States and other developed countries have shown that as many as 30%–50% of infants with CCHD are discharged after birth without being identified. This diagnostic gap is likely to be even higher in low-resource countries. Several large randomized trials have shown that the use of universal pulse-oximetry screening (POS) at the time of discharge from birth hospi

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Utomo, Martono Tri. "Neonatal Sepsis in Low Birth Weight Infants in Dr. Soetomo General Hospital." Indonesian Journal of Tropical and Infectious Disease 1, no. 2 (May 3, 2010): 86. http://dx.doi.org/10.20473/ijtid.v1i2.2172.

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Infections of the newborn are a significant cause of mortality. Preterm infant have a high risk sepsis.. The incidence of neonatal sepsis is 1 to 10 cases per 1000 live births and 1 per 250 live premature births. To describe the characteristics of neonatal sepsis in the low birth weight infant in the neonatal intensive care unit Dr. Soetomo Hospital. Retrospective analysis. The data were collected from the medical record of low birth weight infants who were diagnosed as sepsis in neonatal care unit of Dr. Soetomo Hospital between January 2010 to June 2010 with purposive sampling. Descriptive a

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Goberman, Alexander M., and Jason A. Whitfield. "Acoustics of Infant Pain Cries: Fundamental Frequency as a Measure of Arousal." Perspectives on Speech Science and Orofacial Disorders 23, no. 1 (July 2013): 18–26. http://dx.doi.org/10.1044/ssod23.1.18.

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Purpose: The goal of the current study is to examine fundamental frequency (F0) from a sample of healthy newborn infant pain cries. Methods: A total of 58 healthy infants were included in the study. Data were examined from the first cry following a pain stimulus, in addition to a comparison of the first 30 seconds and the last 30 seconds of the entire crying episode. Results: In the current study, the mean F0 was found to decrease over time (regardless of infant sex, term status, or positioning). The data also showed a significantly higher F0 for preterm female infants (compared to preterm mal

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Köstlin-Gille, Natascha, Lara-Antonia Flaig, Marco Ginzel, Jörg Arand, Christian F. Poets, and Christian Gille. "Granulocytic Myeloid-Derived Suppressor Cells in Breast Milk (BM-MDSC) Correlate with Gestational Age and Postnatal Age and Are Influenced by Infant’s Sex." Nutrients 12, no. 9 (August 25, 2020): 2571. http://dx.doi.org/10.3390/nu12092571.

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Background: Infections are the main cause of death in preterm infants. Causative agents often descend from the intestinal flora of the infected neonate, indicating insufficient protection by the mucosal barrier. Breast milk (BM) contains different subsets of immune cells. We recently showed that BM contains significant numbers of myeloid-derived suppressor cells (MDSC)—immune cells that actively suppress pro-inflammatory immune responses—and hypothesized that the transfer of BM-MDSC may modulate the mucosal immunity of the newborn. Methods: Percentages of MDSC in the BM from mothers of 86 pret

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Aleksi-Meskhishvili, V. V., and Yury A. Kozlov. "SURGICAL TREATMENT OF OPEN DUCTUS ARTERIOSUS IN PREMATURE INFANTS." Russian Journal of Pediatric Surgery 22, no. 3 (August 16, 2018): 148–54. http://dx.doi.org/10.18821/1560-9510-2018-22-3-148-154.

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The open arterial duct (OAD) means the maintenance of the OAD patency in the postnatal period within 48-72 hours after birth. OAD in preterm infants is of particular importance and often determines their survival. The presence of OAD significantly reduces chances of premature babies to recover, as it contributes to the emergence and aggravation of diseases such as necrotizing enterocolitis (NEC), bronchopulmonary dysplasia (BPD), renal dysfunction, intraventricular hemorrhage (IVH), cerebral palsy and, often, the death of a newborn. From this point of view, there is appeared the importance of

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Reynolds, E. Osmund R. "New Noninvasive Techniques for Assessing Brain Oxygenation and Hemodynamics." International Journal of Technology Assessment in Health Care 7, S1 (January 1991): 125–27. http://dx.doi.org/10.1017/s0266462300012642.

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Infants who require intensive care are at considerable risk of death or long-term neurodevelopmental disability. Therefore, noninvasive methods have been sought for assessing the structure and function of the brain in the immediate newborn period. The major aims are to investigate the prevalence and mechanisms of brain-damaging lesions, to test preventive strategies and treatment, and to assign the prognosis of the infants. Several methods have proved their worth, e.g., ultrasound imaging, electroencephalography, including the testing of evoked potentials, and Doppler ultrasonography for measu

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Samudro, Heru, and Mulyadi M. Djer. "Inhaled iloprost as part of combination therapy for persistent pulmonary hypertension of the newborn." Paediatrica Indonesiana 52, no. 1 (March 3, 2012): 57. http://dx.doi.org/10.14238/pi52.1.2012.57-60.

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Persistent pulmonary hypertension of thenewborn (PPHN) is rare, but life-threatening.If not treated, PPHN may cause respiratoryfailure and death in neonates. l,2,3 PPHNoften occurs in term or post-term infants with a historyof difficult labor, infection or asphyxia during birth.These infants do not have adequate oxygen duringlabor.3 Based on etiology, PPHN can be categorizedinto primary PPHN, which occurs by itself withoutapparent cause; or secondary PPHN, which is causedby meconium aspiration, hyaline membrane disease,neonatal sepsis with pneumonia, congenital heartabnormality, or maternal dr

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Heere, Megan, Beth Moughan, Joseph Alfonsi, Jennifer Rodriguez, and Stephen Aronoff. "Effect of Education and Cardboard Bassinet Distribution on Newborn Bed-Sharing." Global Pediatric Health 6 (January 2019): 2333794X1982917. http://dx.doi.org/10.1177/2333794x19829173.

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Objective. This study sought to determine if infant sleep education plus a cardboard bassinet reduced bed-sharing, a risk factor for sudden infant death syndrome (SIDS) and sleep-related deaths (SRD), in the first week of life. Methods. Women delivered between 1/1/2015-11/15/2016 were interviewed by phone within 72 hours of discharge. Control 1 delivered through 10/31/2015 (previously reported); Control 2: 11/1/2015-2/7/2016; Intervention 1 received inpatient safe sleep education and delivered between 2/8/2016-5/4/2016; Intervention 2 also received a cardboard bassinet and delivered after 5/4/

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Petousis-Harris, Helen, Yannan Jiang, Lennex Yu, Donna Watson, Tony Walls, Nikki Turner, Anna S. Howe, and Jennifer B. Griffin. "A Retrospective Cohort Study of Safety Outcomes in New Zealand Infants Exposed to Tdap Vaccine in Utero." Vaccines 7, no. 4 (October 11, 2019): 147. http://dx.doi.org/10.3390/vaccines7040147.

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We aimed to evaluate the safety of maternal Tdap; thus, we assessed health events by examining the difference in birth and hospital-related outcomes of infants with and without fetal exposure to Tdap. This was a retrospective cohort study using linked administrative datasets. The study population were all live-born infants in New Zealand (NZ) weighing at least 400 g at delivery and born to women who were eligible for the government funded, national-level vaccination program in 2013. Infants were followed from birth up to one year of age. There were a total of 69,389 eligible infants in the coh

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Magalhães, Mauricio, Francisco Paulo Martins Rodrigues, Maria Renata Tollio Chopard, Victoria Catarina de Albuquerque Melo, Amanda Melhado, Inez Oliveira, Clery Bernardi Gallacci, Paulo Roberto Pachi, and Tabajara Barbosa Lima Neto. "Neuroprotective body hypothermia among newborns with hypoxic ischemic encephalopathy: three-year experience in a tertiary university hospital. A retrospective observational study." Sao Paulo Medical Journal 133, no. 4 (October 28, 2014): 314–19. http://dx.doi.org/10.1590/1516-3180.2013.7740026.

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CONTEXT AND OBJECTIVE:Neonatal hypoxic-ischemic encephalopathy is associated with high morbidity and mortality. Studies have shown that therapeutic hypothermia decreases neurological sequelae and death. Our aim was therefore to report on a three-year experience of therapeutic hypothermia among asphyxiated newborns.DESIGN AND SETTING:Retrospective study, conducted in a university hospital.METHODS:Thirty-five patients with perinatal asphyxia undergoing body cooling between May 2009 and November 2012 were evaluated.RESULTS:Thirty-nine infants fulfilled the hypothermia protocol criteria. Four newb

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Sedin, Gunnar. "CPAP and Mechanical Ventilation." International Journal of Technology Assessment in Health Care 7, S1 (January 1991): 31–40. http://dx.doi.org/10.1017/s0266462300012472.

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Respiratory insufficiency has previously been a frequent cause of neonatal death, especially in preterm infants. As late as in 1967, Silverman and associates (66) found that in infants with hyaline membrane disease (HMD), mechanical ventilation with a body-enclosing negative pressure respirator did not improve survival. Before 1970, the mortality among infants who required respiratory therapy was high (20;46;70). At the end of the 1960s and the beginning of the 1970s, several new methods were introduced to improve ventilation of newborn infants. Kirby and coworkers (41) introduced intermittent

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Znamenska, Тetiana, Оlha Vorobiova, Тetiana Holota, Yurii Marushko, and Valerii Pokhylko. "THE IMPORTANCE OF CARNITINE AND ITS METABOLISM IN NEWBORN: LITERATURE REVIEW AND CLINICAL CASE." Emergency Medical Service 8, no. 2 (2021): 100–103. http://dx.doi.org/10.36740/emems202102107.

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Aim: To analyze the literature on the processes of formation of endogenous and exogenous carnitine, its metabolism and function in the newborn. Material and methods: The literature data and international clinical recommendations for pathological conditions leading to primary and secondary carnitine deficiency have been retrospectively analyzed. A clinical case of a child with suspected systemic carnitine deficiency is presented. Conclusions: Depending on the reasons that led to carnitine deficiency, there are primary and secondary carnitine deficiency. Primary carnitine deficiency is a rare co

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Vettukattil, Joseph J. "Target Oxygen Levels and Critical Care of the Newborn." Current Pediatric Reviews 16, no. 1 (April 9, 2020): 2–5. http://dx.doi.org/10.2174/1573396315666191016094828.

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Despite our growing experience in the medical care of extremely preterm infants and critically ill neonates, there are serious gaps in the understanding and clinical application of the adaptive physiology of the newborn. Neonatal physiology is often misinterpreted and considered similar to that of adult physiology. The human psyche has been seriously influenced, both from an evolutionary and survival point of view, by the cause and effect of hypoxemia which is considered as a warning sign of impending death. Within this context, it is unimaginable for even the highly trained professionals to c

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Boucek Jr, Robert J., Mark M. Boucek, and Alfred Asante-Korang. "Advances in methods for surveillance of rejection." Cardiology in the Young 14, S1 (February 2004): 93–96. http://dx.doi.org/10.1017/s1047951104006377.

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Transplantation is an effective treatment modality for infants1 and children2 with end-stage cardiac diseases. Rejection remains a major complication (Figure 1), even in newborn infants.3 Acute rejection can best be operationally defined by clinical findings, histopathology, and/or abnormalities of ventricular function of new origin that require, and respond to, intensified immunosuppression. Mechanistically, the ability to detect acute rejection is critically dependent on the detection of significant new myocytic injury, damage, and/or death. Surveillance for rejection is critically important

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