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Libros sobre el tema "Non-clinical studies"

Autor: Grafiati
Publicado: 25 de mayo de 2024
Última modificación: 31 de julio de 2025

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1

International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. and Canada Therapeutic Products Directorate, eds. Timing of non-clinical safety studies for the conduct of human clinical trials for pharmaceuticals. Therapeutic Products Directorate, Health Canada, 1997.

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2

Bartu, Anne. Evaluation of a preventative intervention strategy in a non-clinical setting using computerised screening. Western Australian Alcohol & Drug Authority, 1991.

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3

M, Burns Suzanne, and American Association of Critical-Care Nurses., eds. AACN protocols for practice. 2nd ed. Jones and Bartlett Publishers, 2006.

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4

Giffney, Noreen. Developing Clinical Insight Using Non-Clinical Case Studies in Psychoanalysis and Psychotherapy. Taylor & Francis Group, 2021.

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5

Giffney, Noreen. Developing Clinical Insight Using Non-Clinical Case Studies in Psychoanalysis and Psychotherapy. Taylor & Francis Group, 2021.

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6

Food and Drug Administration Staff. Compact Regs - Good Laboratory Practice for Non-Clinical Laboratory Studies. Taylor & Francis Group, 2004.

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7

Beckett, Ronald G., Gerald J. Conlogue, and Andrew J. Nelson. Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. CRC Press, 2020. http://dx.doi.org/10.4324/9780429318597.

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8

Nelson, Andrew, Ronald G. Beckett, and Gerald J. Conlogue. Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. Taylor & Francis Group, 2020.

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9

Nelson, Andrew, Ronald G. Beckett, and Gerald J. Conlogue. Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. Taylor & Francis Group, 2020.

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10

Beckett, Ronald G., Andrew J. Nelson, and Gerald J. Conlogue. Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. Taylor & Francis Group, 2020.

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11

Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. Taylor & Francis Group, 2024.

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12

Nelson, Andrew, Ronald G. Beckett, and Gerald J. Conlogue. Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. Taylor & Francis Group, 2020.

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13

Nelson, Andrew, Ronald G. Beckett, and Gerald J. Conlogue. Case Studies for Advances in Paleoimaging and Other Non-Clinical Applications. Taylor & Francis Group, 2020.

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14

Peacock, Martin. Correction for non-linearity due to small objects in clinical PET studies. 1996.

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15

dickey, lore m. Case Studies in Clinical Practice with Trans and Gender Non-Binary Clients. Jessica Kingsley Publishers, 2021. http://dx.doi.org/10.5040/9781805015123.

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Exploring clinical examples of the lived experiences of trans people across the lifespan, this unique and authoritative book addresses topics such as attending school, puberty, employment issues, suicide, bullying, autism and intersecting identities. Divided into three sections, childhood, adolescence, and adulthood, the book brings the case studies to life and dispels common myths by including short responses from leading professional experts. By enabling a greater knowledge of work with trans people and therefore filling an important gap in available literature, Case Studies in Clinical Prac
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16

Hoberman. Pediatric Non-Clinical Drug Testing: Principles, Requirements, and Practices for Juvenile Toxicology Studies. Wiley & Sons, Limited, John, 2023.

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17

Ibritumomab Tiuxetan (Zevalin) in Non-Hodgkin's Lymphoma: Clinical Background, Practical Considerations, and Case Studies. Oncology Group, 2003.

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18

Administration, Food and Drug. Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-Clinical Laboratory Studies. Taylor & Francis Group, 2002.

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19

Administration, Food and Drug. Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-Clinical Laboratory Studies. Taylor & Francis Group, 2002.

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20

Administration, Food and Drug. Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-Clinical Laboratory Studies. Taylor & Francis Group, 2002.

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21

Administration, Food and Drug. Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-Clinical Laboratory Studies. Taylor & Francis Group, 2002.

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22

Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-clinical Laboratory Studies (10 Pack). 2nd ed. Informa Healthcare, 2003.

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23

McCaul, Thomas Russell *. The use of clinical supervision for enhancing teacher reflections on the teaching of non-academic students: two case studies. 1991.

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24

Interpharm. Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-Clinical Laboratory Studies 10 Pack, Second Edition. Taylor & Francis Group, 2013.

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25

Interpharm. Compact Regs Part 58: CFR 21 Part 58 Good Laboratory Practice for Non-Clinical Laboratory Studies 10 Pack, Second Edition. Taylor & Francis Group, 2013.

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26

Dickey, Lore M., and Marsha Botzer. Case Studies in Clinical Practice With Trans and Gender Non-binary Clients: A Handbook for Working With Children, Adolescents, and Adults. Jessica Kingsley Publishers, 2021.

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27

dickey, lore m., and Marsha Botzer. Case Studies in Clinical Practice with Trans and Gender Non-Binary Clients: A Handbook for Working with Children, Adolescents, and Adults. Kingsley Publishers, Jessica, 2021.

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28

Elwood, Mark. Critical Appraisal of Epidemiological Studies and Clinical Trials. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199682898.001.0001.

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This book presents a system of critical appraisal applicable to clinical, epidemiological and public health studies and to many other fields. It assumes no prior knowledge. The methods are relevant to students, practitioners and policymakers. The book shows how to assess if the results of one study or of many studies show a causal effect. The book discusses study designs: randomised and non-randomised trials, cohort studies, case-control studies, and surveys, showing the presentation of results including person-time and survival analysis, and issues in the selection of subjects. The system sho
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29

Ghaemi, Nassir. Clinical Psychopharmacology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199995486.001.0001.

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Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores the science and art of clinical research and its individualized application. Content is primarily based on clinical research and pharmacological studies, unlike most texts that rely on inferences from biological mechanisms. The text consists of 49 chapters, organized into 6 sections, focusing on disease-modifying versus symptomatic effects of available treatments, careful differential diagnosis including non-DSM diagnostic concepts, key clinical research studies, essential facts about the most common dr
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30

Pereira, Mark A. Nutrition and Type 2 Diabetes: Etiology and Prevention. Taylor & Francis Group, 2013.

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31

Pereira, Mark A. Nutrition and Type 2 Diabetes: Etiology and Prevention. Taylor & Francis Group, 2013.

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32

Pereira, Mark A. Nutrition and Type 2 Diabetes. Taylor & Francis Group, 2019.

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33

Pereira, Mark A. Nutrition and Type 2 Diabetes: Etiology and Prevention. Taylor & Francis Group, 2013.

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34

Nutrition and Type 2 Diabetes. Taylor & Francis Group, 2013.

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35

Katumbay, Desire Tshala. On the Site of the Lesion in Konzo: Clinical and Neurophysiological Studies on a Non-Progressive Upper Motor Neuron Disorder (Comprehensive Summaries of ... from the Faculty of Medicine, 1092). Uppsala Universitet, 2001.

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36

Knud, Rasmussen. Non-invasive quantitative measurement of blood flow and estimation of vascular resistance by the Doppler ultrasound method: Methodological studies and clinical application on the fetus and the transplanted kidney allograft. 1991.

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37

Gray, Nathan A., and Thomas W. LeBlanc. Early Palliative Care for Patients with Metastatic Non-Small Cell Lung Cancer (DRAFT). Edited by Nathan A. Gray and Thomas W. LeBlanc. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190658618.003.0001.

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This chapter provides an overview and commentary on the 2010 study by Temel and colleagues regarding early palliative care for patients with non-small cell lung cancer. It describes the trial design and findings while also providing a concise critique of the study and a brief review of relevant subsequent studies. The chapter describes the basics of the study, including funding, year study began, year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chap
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38

Lhatoo, Samden D., Philippe Kahane, and Hans O. Lüders, eds. Invasive Studies of the Human Epileptic Brain. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198714668.001.0001.

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No other neurological condition allows the same opportunities for intracranial electrophysiological study of the human brain as epilepsy does. What ensues is exponentially expanding knowledge of the human epileptic brain, as well as windows into the physiology of the normal human brain itself. In Invasive Studies of the Epileptic Human Brain, some of the most renowned epilepsy experts of the twentieth and twenty-first centuries provide their expertise and insights into the identification and mapping of intracranial epileptiform and non-epileptiform activity, mapping of human brain function, an
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39

Ray, Sumantra (Shumone), Sue Fitzpatrick, Rajna Golubic, Susan Fisher, and Sarah Gibbings, eds. Clinical trial supplies: investigational medicinal products (IMPs). Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199608478.003.0017.

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This chapter describes the procedures and records associated with accountability of investigational and non-investigational medicinal products (IMP and NIMP) used in clinical trials, to show that the drug has been labelled according to the regulations, stored in conditions to keep it stable, prepared and administered to the correct subjects in accordance with the protocol, has been fully accounted for and destroyed if unused. Manufacture of IMP is discussed together with methods of blinding. The role of the Qualified person (QP) is reviewed. The need for study drug accountability is discussed
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40

Ray, Sumantra (Shumone), Sue Fitzpatrick, Rajna Golubic, Susan Fisher, and Sarah Gibbings, eds. Setting the scene and ICH GCP in clinical and healthcare research. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199608478.003.0008.

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This chapter looks at the purpose and history of the development of good clinical practice (GCP). The international conference on harmonisation (ICH) GCP is the international quality standard for conducting clinical research to ensure the rights and well-being of patients are protected and the resulting data are valid. The cornerstone of ethics in research stems from the Declaration of Helsinki and the chapter looks at the changes in the Declaration and the impact on clinical trials. The development of the ICH process is described and the E, S, Q and M guidelines are discussed, The efficacy gu
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41

Gross, Wolfgang L., and Julia U. Holle. Clinical features of ANCA-associated vasculitis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0131.

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The primary ANCA-associated vasculitides are granulomatosis with polyangiitis (Wegener's, GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss syndrome, CSS). They predominantly affect small (and medium-sized) vessels and share a variable association with ANCA (anti-neutrophil cytoplasm antibody) directed against neutrophil proteinase 3 (PR3, mainly in GPA) and myeloperoxidase (MPO, mainly in MPA and CSS). Crescentic necrotizing glomerulonephritis and alveolar haemorrhage due to pulmonary capillaritis represent classical (vasculitic) orga
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42

Farhood, Laila Faris. WAR AND NON-WAR STRESSORS, FAMILY RESOURCES, COPING AND FAMILY ADAPTATION AMONG LEBANESE FAMILIES. 1993.

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43

Bliss, Alison. Paediatric pain epidemiology. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0055.

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The landmark paper discussed in this chapter reviewed 51 epidemiological studies looking at the incidence and prevalence of both acute pain and chronic pain in children and adolescents. The paper divided the studies they reviewed into two broad categories: those which examined pain in non-clinical populations, such as school children or general population samples, and those which examined pain in clinical settings, such as inpatients, outpatients from specific clinics, or special populations. In the clinical studies assessed, back pain in athletes and overuse injury syndrome in musicians were
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44

Brunoni, Andre Russowsky, Bernardo de Sampaio Pereira Júnior, and Izio Klein. Neuromodulatory approaches for bipolar disorder: current evidences and future perspectives. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0028.

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Bipolar disorder is a prevalent condition, with few therapeutic options and a high degree of refractoriness. This justifies the development of novel non-pharmacological treatment strategies, such as the non-invasive techniques of transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), as well as the invasive techniques of deep brain stimulation (DBS) and vagus nerve stimulation (VNS). In this chapter, we provide a summary of the development of the techniques as well as the studies carried out with patients with bipolar disorder. Although many promising resul
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45

Polanczyk, Guilherme V. Epidemiology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198739258.003.0013.

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This chapter initially reviews the main methodological aspects of ADHD prevalence studies, specifically study design, case definition, and ascertainment to subsequently address meta-analyses summarizing the prevalence of the disorder on children, adolescents, and adults. Results of meta-regression in the context of meta-analysis have investigated the effect of year of publication, sample location, and methodological characteristics of studies on heterogeneity of results. Studies on the course of the disorder, following up clinical and community samples, are discussed, as well as cultural influ
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46

Dalzell, Heidi, and Kayti Protos. A Clinician’s Guide to Gender Identity and Body Image. Jessica Kingsley Publishers, 2020. http://dx.doi.org/10.5040/9781805014782.

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This accessible guide for clinicians and clinical students working in the fields of eating disorders and transgender health psychology offers useful tips, constructive case studies and reflective questions that enable readers to feel better equipped in supporting their clients’ needs. The book addresses the clinical challenges a therapist may encounter, and provides advice on the key issues involved in therapeutic work with transgender, non-binary and gender-expansive clients, including trauma, minority stress, coming out, family support, appearance and body changes. This book will inspire cli
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47

Abhishek, Abhishek, Adrian Jones, and Michael Doherty. Topical pharmacological treatments. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0028.

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Topical pharmacological agents such as non-steroidal anti-inflammatory drugs (NSAIDs) and capsaicin are widely recommended as first-line analgesics in the treatment of osteoarthritis (OA) of the knee, hand, and potentially other peripheral joints in view of their safety and efficacy. Although initial studies were short in duration (2–4 weeks), recent randomized controlled trials have confirmed the efficacy of topical NSAIDs over longer (12-week) study periods. Systematic reviews demonstrate that their efficacy can be equivalent to oral NSAIDs for OA pain, but they have a significantly better s
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48

Zaiwalla, Zenobia, and Roo Killick. Sleep disorders. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199688395.003.0035.

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As sleep medicine advances, there is increasing demand on services including neurophysiology to investigate sleep disorders. This chapter classifies the sleep disorders according to the main symptom presenting to the clinician, including excessive daytime sleepiness, insomnia, patients sleeping at the wrong times due to a circadian rhythm disorder, and movements or behaviours in sleep. The clinical presentation of common sleep disorders in each category are outlined, including obstructive sleep apnoea, narcolepsy, restless leg syndrome, periodic leg movements disorder, circadian rhythm disorde
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49

Nilipour, Reza. Neurolinguistics. Edited by Anousha Sedighi and Pouneh Shabani-Jadidi. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198736745.013.18.

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This chapter summarizes some first neurolinguistic studies conducted in Persian, using patholinguistic data taken from monolingual and bilingual brain-damaged patients, as well as five first neuroimaging studies in healthy native speakers of Persian. The patholinguistic data are extracted from formal clinical linguistic assessments of a heterogeneous group of brain-damaged patients with different etiologies and brain lesion sites. The data are indicative of general agrammatic features of ‘syntactic simplification’ and ‘morphological regression’ reported in cross-language studies, along with la
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50

Schnider, Armin. Types of confabulation. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198789680.003.0003.

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When the term ‘confabulation’ entered the medical literature, it referred to the emergence of memories of events and experiences that never happened. However, its Latin root—meaning ‘to gossip, to chat’—allowed for a broader use of the term. This chapter gives the classic and the present-day definitions of confabulations and proposes a distinction between memory-related (mnestic) and non-memory-related (non-mnestic) confabulations. Early clinical observations already suggested the distinction between different forms of mnestic confabulations. Based on the literature and our own studies, I prop
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