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Tesis sobre el tema "Olfactory bulb"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 26 de julio de 2025

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1

Smith, Richard. "Neuromodulation in the Olfactory Bulb." Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066194/document.

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La neuromodulation de circuits olfactifs par l'acétylcholine (ACh) joue un rôle important dans la discrimination et l'apprentissage d’odeur. Le traitement précoce des signaux chimiosensoriels se produit dans deux régions fonctionnellement et anatomiquement distinctes, les principaux et accessoires bulbes olfactifs (MOB et AOB), qui reçoivent entrée cholinergique significative du cerveau antérieur basal. Ici, nous explorons la régulation des circuits de l’AOB et la MOB par ACh, et comment cette modulation influence le comportement à médiation olfactifs. De manière surprenante, malgré la présenc
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2

Sanz, Diez Alvaro. "Functional study of mouse olfactory bulb inhibitory circuits." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAJ037/document.

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Les cellules periglomerulaires du bulbe olfactif conforment une population hétérogène avec des propriétés moléculaires, synaptiques, morphologiques et biophysiques diverses toujours étudiés de façon indépendante. Toutefois, cette diversité suggère que des groupes différents des cellules periglomerulaires pourraient avoir des rôles différents. Dans la première partie de ma thèse je cherche à associer, pour la première fois, différents marqueurs de la diversité des neurones periglomerulaires de façon à aider à comprendre les potentielles implications fonctionnelles que les cellules periglomerula
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3

Provost, Allison. "Serotonergic Modulation of the Olfactory Bulb." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17463145.

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Serotonin is a neuromodulator whose actions are thought to modulate mood and brain states. Growing evidence correlates perturbations in the serotonergic system with neuropsychiatric diseases ranging from depression to schizophrenia. The dorsal raphe nucleus (DRN), a serotonergic cluster of neurons in the brainstem, projects widely throughout anterior brain regions, including the olfactory bulb. Electrophysiological recordings from the DRN show that its activity fluctuates with behavior over hundreds of milliseconds. Study of serotonergic modulation of the olfactory bulb has focused on modulati
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4

Murphy, Gabe J. "Synaptic processing in olfactory bulb glomeruli /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3137220.

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5

Goodman, Melba Nadine. "Interactions between olfactory bulb astrocytes, ensheathing cells and olfactory sensory neurons." Case Western Reserve University School of Graduate Studies / OhioLINK, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=case1060869724.

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6

Mazo, Camille. "GABAergic signaling in cortical feedback to the olfactory bulb." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066066/document.

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Les projections corticales de retour conduisent l'information vers des relais de traitement de l'information plus précoces. Elles sont essentielles pour la perception sensorielle. En ce qui concerne l'olfaction, l'information sensorielle est constituée d'une multitude de molécules odorantes, et c'est ce mélange complexe qui pénètre dans la cavité nasale. En fonction du contexte, c'est une partie ou une autre de cet ensemble de molécules qui va être importante d'un point de vue comportemental. Les signaux corticaux de retour permettraient de focaliser son attention sur les odeurs pertinentes de
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7

de, Oliveira Pimentel Diogo. "Intratraglomerular communication in the mammalian olfactory bulb." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/1446292/.

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The olfactory bulb (OB) is the first processing structure in the olfactory system it receives direct sensory input from the olfactory sensory neurons and relays processed information to the olfactory cortex and other structures in the brain. The axons from sensory neurons expressing the same olfactory receptor molecule converge onto the same discrete structure on the surface of the OB, termed glomerulus. Each glomerulus forms a modular unit which confines the single apical tufts of about 25 mitral cells (MC). Understanding how intraglomerular cells communicate with one another will therefore i
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8

Bhalla, Upinder Singh Bower James M. "Information processing in the mammalian olfactory bulb." Diss., Pasadena, Calif. : California Institute of Technology, 1993. http://resolver.caltech.edu/CaltechTHESIS:12092009-100507031.

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Thesis (Ph. D.)--California Institute of Technology, 1993. UM #93-25,337.<br>Advisor names found in the Acknowledgments pages of the thesis. Title from home page. Viewed 02/18/2010. Includes bibliographical references.
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9

Malvaut, Sarah, and Sarah Malvaut. "The role of different subtypes of olfactory bulb interneurons in olfactory behavior." Doctoral thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37555.

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Le bulbe olfactif (BO) représente dans le cerveau le premier relai dans le traitement des informations olfactives. Au niveau de cette structure, plusieurs types de neurones sont impliqués dans la modulation de l’information odorante, avant même que celle-ci ne soit envoyée vers des structures corticales supérieures. Parmi eux se trouvent les cellules granulaires (CGs), une population d’interneurones régulant de manière importante l’activité des cellules principales du BO. De manière intéressante, le BO est capable à l’âge adulte de produire et régénérer une partie de sa population interneurona
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10

Doucette, Wilder Thorne. "A searchlight for meaning in the olfactory bulb /." Connect to abstract via ProQuest. Full text is not available online, 2008. http://proquest.umi.com/pqdweb?did=1553309631&sid=1&Fmt=2&clientId=18952&RQT=309&VName=PQD.

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Thesis (Ph.D. in Neuroscience) -- University of Colorado Denver, 2008.<br>Typescript. Includes bibliographical references (leaves 140-153). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;
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11

Jordan, R. "Context dependent processing in the mouse olfactory bulb." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10044533/.

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Optimal behavioural strategies necessitate the ability to flexibly respond to sensory stimuli according to behavioural context. Contextual information can be defined as internally generated information that gives behavioural meaning to primary sensory stimuli, for example: hunger state, reward associations and other learned information. The olfactory bulb (OB) is the very first site of odour information processing, yet a large variety of contextual information has been described in its activity. To investigate the mechanistic basis of this, I used whole cell patch recordings from identified mi
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12

Tenza, Ferrer Helia. "The role of microglia in the olfactory bulb." Master's thesis, Université Laval, 2014. http://hdl.handle.net/20.500.11794/25419.

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Les microglies sont petites cellules gliales du système nerveux centrale (SNC) considérées comment les cellules immunitaires pour la ressemblance avec les macrophages et la capacité de phagocyter. Bien quelles sont distribués partout le SNC, la densité, la morphologie et l’état d’activation de la microglie diffère selon la région du cerveau. Il a été signalé récemment que les microglies sont fortement activées dans le bulbe olfactif (OB) des souris saines. C’est cet état constant d’activation qui nous suggère que les microglies peuvent jouer un rôle crucial dans l'OB. Dans cette étude, nous av
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13

Allen, Zegary J. "Transcription Factor Regulation of Olfactory Bulb Interneuron Heterogeneity." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1273166739.

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14

Ford, Neil C. "Centrifugal Input Modifies Spontaneous Activity of Olfactory Bulb Neurons." University of Cincinnati / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368012904.

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15

Lee, Mary Elizabeth. "Axon growth and neuron-glia interactions in the olfactory system /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/5684.

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16

Byrd, Christine Ann. "Interactions between the olfactory placode and the olfactory bulb during development in Xenopus laevis." Diss., The University of Arizona, 1992. http://hdl.handle.net/10150/186063.

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The relationship between olfactory receptor-cell axons and the output cells of the olfactory bulb (the mitral/tufted cells) was analyzed during normal development and following experimental manipulation to investigate the role of olfactory afferent axons in the induction of olfactory-bulb formation. A light- and electron-microscopic study of Xenopus embryos, larvae, and adult frogs outlined the major events in olfactory-bulb formation. Axons were observed in the neural tube immediately before the future olfactory-bulb neurons began to differentiate. Quantitative analysis during normal developm
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17

Maresh, Alison. "Cellular and Synaptic Organization of the Human Olfactory Bulb." Yale University, 2008. http://ymtdl.med.yale.edu/theses/available/etd-08212007-112805/.

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The distribution of cell types and synapses is well characterized in the rodent olfactory bulb (OB), and from that plausible models of odor processing have been constructed. Individual olfactory sensory neurons (OSNs) express only 1 of ~1000 odorant receptors (ORs) and send their axons to specific synaptic targets in the OB glomerular neuropil. Each glomerulus is innervated exclusively by OSN axons expressing the same OR. The distribution of these glomeruli is conserved across animals, as is the numerical relationship between number of expressed ORs and number of glomeruli in the OB. Our objec
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18

Ford, Neil C. "Centrifugal Input Modifies Spontaneous Activity of Olfactory Bulb Neurons." Thesis, University of Cincinnati, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1548544.

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<p> The specific aim of this thesis was to examine the effects of centrifugal input on the spontaneous activity of main olfactory bulb (MOB) neurons. Spontaneous activity is the ability of a neuron to generate action potentials in the absence of external stimuli. In order to study the effects of centrifugal fibers on the spontaneous activity of bulbar neurons, impulse conduction of these fibers was blocked using a reversible chemical blockade, while simultaneously recording spontaneous activity in the MOB. Our results show that blocking centrifugal input does modulate the levels of spontane
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19

Davison, A. P. "Mathematical modelling of information processing in the olfactory bulb." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598407.

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The aim of this dissertation is to investigate the processing of sensory signals in the mammalian olfactory bulb, using analysis and computer simulation of mathematical models. A biologically-detailed mathematical model provides a framework which integrates the results of experiments at different levels of enquiry, and enables study of problems which cannot easily be addressed using only the methods of experimental neuroscience. Specific biological and computational problems which are addressed include: the existence, origin and role of oscillations/synchronization; how the properties of indiv
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20

Franceschini, Isabelle A. "Cellular and molecular studies on olfactory bulb ensheathing cells." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301803.

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21

Breton-Provencher, Vincent. "Integration and function of adult-born olfactory bulb neurons." Doctoral thesis, Université Laval, 2014. http://hdl.handle.net/20.500.11794/25790.

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La récente découverte de la formation de nouveaux neurones dans certaines régions du cerveau adulte a remis en question notre conception des processus de plasticité neuronale. Dans le bulbe olfactif d’un adulte, il y a chaque jour des milliers de cellules qui envahissent le réseau bulbaire. La façon par laquelle ces neurones générés à l’âge adulte intègrent un réseau neuronal pré-existant demeure jusqu’à ce jour inexpliquée. De plus, nous ne savons toujours pas pourquoi il y a de nouveaux neurones qui sont formés dans le cerveau adulte. Nous avons examiné, dans un premier temps, le processus d
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22

Gao, Yuan. "Mechanisms of Synaptic Plasticity in the Rat Olfactory Bulb." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1255576963.

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23

Balu, Ramani. "Intrinsic and Synaptic Properties of Olfactory Bulb Neurons and Their Relation to Olfactory Sensory Processing." Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1173540900.

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24

O'Connor, Simon. "Modelling gap junction-coupled networks of olfactory bulb mitral cells." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/55041/.

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The olfactory bulb forms the first level of input integration for olfactory receptor neurons that receive stimuli from odorant molecules in the nose. The olfactory bulb is multi channel in nature, with each channel containing its own populations of mitral cells. These channels each handle the input from neurons expressing a single type of olfactory receptor protein tuned to a unique range of odorant structures. I have constructed a mitral cell gap-junction network model with morphologically accurate mitral cells to study the behaviour of mitral cells in a channel population. The passive parame
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25

Guo, Luzhi. "Ultrastructural characteristics of cultured embryonic mouse olfactory epithelial and bulb cells." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc798462/.

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This laboratory is involved in physiological and histochemical studies of olfactory tissue grown in cell culture in an attempt to create an in vitro model of the olfactory system. The present study is an in-depth ultrastructural study of the morphology of cultured olfactory cells to determine the extent of similarities and differences between cultured tissues and the intact olfactory system in vivo.
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26

Bywalez, Wolfgang [Verfasser], and Veronica [Akademischer Betreuer] Egger. "Physiology of rodent olfactory bulb interneurons / Wolfgang Bywalez ; Betreuer: Veronica Egger." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1114068098/34.

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27

Yuan, Tifei, and 袁逖飞. "Self-assembling peptide nanofiber scaffold treatment to acutely injured olfactory bulb." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43816277.

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28

Burton, Shawn D. "Novel Cell Types and Circuits in the Mouse Main Olfactory Bulb." Research Showcase @ CMU, 2016. http://repository.cmu.edu/dissertations/686.

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The mammalian olfactory system is strikingly shallow. While peripheral input in other sensory systems is sequentially processed by brainstem, midbrain, and thalamic nuclei before reaching primary sensory and associational cortices, olfactory input is processed by only a single region of the brain – the main olfactory bulb – before reaching higher cortical areas. A tremendous amount of neural processing is thus compressed within the main olfactory bulb, making this region of the brain uniquely well suited for investigating fundamental principles of neural processing. Currently, the identity and
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29

Yuan, Tifei. "Self-assembling peptide nanofiber scaffold treatment to acutely injured olfactory bulb." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43816277.

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30

Pressler, Richard T. "Dr." Connect to text online, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=case1153765647.

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31

Sandström, Malin. "Early Information Processing in the Vertebrate Olfactory System : A Computational Study." Licentiate thesis, KTH, Numerical Analysis and Computer Science, NADA, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4408.

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<p>The olfactory system is believed to be the oldest sensory system. It developed to detect and analyse chemical information in the form of odours, and its organisation follows the same principles in almost all living animals - insects as well as mammals. Likely, the similarities are due to parallel evolution - the same type of organisation has arisen more than once. Therefore, the olfactory system is often assumed to be close to optimally designed for its tasks. Paradoxically, the workings of the olfactory system are not yet well known, although several milestone discoveries have been made du
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32

Winpenny, Eleanor Margaret. "Embryonic and postnatal glutamatergic neurogenesis of the olfactory bulb : the role of Neurogenin2." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609142.

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33

Erskine, A. "Perception and representation of temporally patterned odour stimuli in the mammalian olfactory bulb." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10048012/.

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Sensory stimuli in natural environments are dynamic and complex. The neural circuits of sensory systems in the brain are therefore adapted to extract meaningful information from this dynamic input. An attractive model system for understanding how such sensory input is processed in neural circuits is the mammalian olfactory bulb (OB). The OB has a convenient dorsal anatomical location for e.g. probe implantation, viral delivery and a well-defined circuit architecture. Furthermore, olfaction in rodent models is extremely behaviourally salient and OB circuit function can therefore be efficiently
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34

Hardy, Delphine. "The role of different subtypes of granule cells in the adult olfactory bulb." Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/33035.

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Le bulbe olfactif (BO) est un réseau neuronal complexe qui traite et transfert les informations olfactives aux structures corticales supérieures. Le réseau bulbaire est composé d’une large population de cellules granulaires (CGs) GABAergiques qui sont continuellement renouvelées tout au long de la vie de l’animal. Cette population peut exprimer différents marqueurs neuronaux comme la calretinine (CR+) et la CaMKIIα (CaMKIIα+), mais jusqu’à présent les études ayant eues pour but de comprendre le rôle des CGs dans le BO n’ont pas pris en considération cette hétérogénéité. Cependant, il est possi
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35

Schmidt, Loren Janes. "OLFACTORY BULB SYNCHRONY: SPATIALLY LOCALIZED COINCIDENT INHIBITION OF MITRAL CELLS BY GABAERGIC MICROCIRCUITS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1404390871.

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36

Franchi, Sira Angela. "Mechanism of activation and function of the odorant receptor expressed at the axon terminus-growth cone of olfactory sensory neurons." Doctoral thesis, Università degli studi di Padova, 2014. http://hdl.handle.net/11577/3423781.

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A unique feature in the topographic organization of the olfactory bulb is the “dual role” of the odorant receptor. It detects odorants and it has been suggested to play a critical role in the axonal convergence of olfactory sensory neurons to form glomeruli in specific loci of the olfactory bulb. This spatial segregation of sensory afferents results in the sensory map. A role of the odorant receptors in axon guidance was suggested by genetic experiments demonstrating that manipulations of odorant receptor sequences perturb the sensory map (Wang et al., 1998). This hypothesis was confirmed by s
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37

FOGLI, ISEPPE Alex. "Electrophysiological analysis of voltage-dependent currents in two types of periglomerular cells in the mouse olfactory bulb." Doctoral thesis, Università degli studi di Ferrara, 2015. http://hdl.handle.net/11392/2388998.

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Periglomerular cells represent an important class of interneurons of the olfactory bulb, contributing to the processing of olfactory information coming from the olfactory epithelium. Despite their involvement in the glomerular circuitry, a larger number of data is required to clarify their function. To further complicate matters, several types of periglomerular cells are described in literature. The main goal of my thesis is to provide new information about two types of periglomerular cells: dopaminergic and calretinin-positive neurons. They belong to different classes of periglomerular cells
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38

Belnoue, Laure. "Rôle de la neurogénèse bulbaire dans la mémorisation des odeurs chez la souris." Thesis, Bordeaux 2, 2009. http://www.theses.fr/2009BOR21667/document.

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Le système constitué de la zone sous ventriculaire (ZSV) et du bulbe olfactif (BO) est l’une des deux régions cérébrales capables à l’âge adulte de produire de nouveaux neurones. La mise en évidence de cette neurogénèse adulte bulbaire a suscité un grand nombre d’interrogations quant à son rôle fonctionnel. Cependant les études réalisées dans ce domaine sont rares et contradictoires. L’objectif de cette thèse a été d’étudier l’impact de différentes expériences olfactives sur la neurogénèse afin de mieux comprendre son rôle fonctionnel. Nous avons choisi pour cela deux approches : d’une part l’
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39

Orechio, Dailiany. "Caracterização morfológica e celular da zona subventricular e da corrente rostral migratória em encéfalos de fetos caninos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-29092016-112302/.

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Precursores neurais originados na zona subventricular (ZSV) de algumas espécies animais possuem uma rota de migração neuronal destinada ao bulbo olfatório principal (BOP), onde os neuroblastos migrantes se diferenciam em interneurônios. Esta corrente migratória é mantida na idade adulta. A compreensão de como se organiza na idade fetal é essencial para a compreensão geral e estabelecimento de novas terapias celulares. O objetivo deste estudo é caracterizar a composição celular e organização morfológica da ZSV e da corrente rostral migratória (CRM) em encéfalos de fetos caninos. A ZSV, CRM e BO
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40

Arruda, Denise de. "A célula periglomerular do bulbo olfatório e seu papel no processamento de odores: um modelo computacional." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/59/59135/tde-23092010-171519/.

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Os interneurônios do bulbo olfatório são elementos chave para o entendimento do processamento de odores. O papel funcional desses neurônios ainda não é bem compreendido, em especial o papel da célula periglomerular (PG). O presente trabalho consiste em construir um modelo biologicamente plausível da célula PG e investigar os efeitos dessa célula em conjunto com modelos da célula mitral e da célula granular. Esses modelos são acoplados através de conexões sinápticas inspiradas nas conexões existentes no bulbo olfatório, formando uma pequena rede simplificada. A rede é usada para analisar o efei
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Lorenzon, Paolo. "Ruolo dell'attività spontanea nella formazione dei circuiti neurali del bulbo olfattivo e nell' elaborazione dell'informazione sensoriale." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3423442.

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The mammalian central nervous system relies on precise synaptic connections to function correctly. The development of precise neuronal circuitry is regulated by axon guidance molecules as well as by specific pattern of activity between the pre and the post synaptic elements. In this thesis I focused on activity dependent mechanisms, and we analyzed the role of spontaneous afferent activity in the topographic organization of the olfactory bulb. To address this point we analyzed the intrabulbar connections between isofunctional glomeruli in a line of mice genetically modified to have very li
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42

Lin, Bei-Jung. "Odor modulation of electrical and [Ca2+]i activities in neurons of the olfactory bulb." [S.l.] : [s.n.], 2006. http://webdoc.sub.gwdg.de/diss/2006/bei_jung.

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43

Bramley, Jayne R. "The origins of electrical discharge patterns in the main olfactory bulb of the rat." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/27168.

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In the studies described in this thesis, the electrical activity of single neurones was recorded extracellularly from the olfactory bulb of anaesthetised rats. Mitral cells were identified electrophysiologically by antidromic activation following stimulation of the lateral olfactory tract. Early in these studies, it became apparent that the mitral cells consistently showed a patterned discharge behaviour that has not been previously reported. Mitral cells displayed a characteristic slow, cyclic spontaneous firing pattern, with peaks of activity occurring with a constant periodicity. During the
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44

Bergman, Ulrika. "Transfer and toxicity of some drugs and chemicals in the olfactory mucosa and bulb /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/avh/2000/91-576-5909-5.pdf.

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45

David, Linda. "Adult neurogenesis : regulation, heterogeneity and functions of adult born interneurons in the olfactory bulb." Thesis, Université Laval, 2014. http://www.theses.ulaval.ca/2014/30395/30395.pdf.

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De nouveaux neurones sont continuellement ajoutés au bulbe olfactif adulte par un processus connu sous le nom de neurogénèse adulte. Dans ce processus, les précurseurs d’interneurones qui sont produits dans la zone sous-ventriculaire près du ventricule latéral migrent suivant un trajet préétabli, le courant de migration rostral, avant d’atteindre le bulbe olfactif. Une fois arrivé dans le bulbe olfactif les précurseurs arrivent à maturation, s’intègrent au réseau neuronal existant et jouent un rôle essentiel dans le comportement olfactif. Tout au long des plusieurs étapes de ce processus, une
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46

Angelova, Alexandra. "Molecular, morphological and physiological properties of glutamatergic juxtaglomerular neurons in the mouse olfactory bulb." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0511/document.

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Au cours de la neurogenèse post-natale, des cellules souches prédéterminées résidant dans la zone ventriculo-subventriculaire génèrent continuellement des progéniteurs qui migrent à travers le flux migratoire rostral, se différencient et s'intègrent dans le bulbe olfactif (BO). Dans mon travail de thèse, j’ai démontré que le facteur de transcription bHLH NeuroD6 est spécifiquement et transitoirement exprimé dans le lignage neurogenique dorsal qui génère les cellules juxtaglomérulaires (CJGs) glutamatergiques pour le bulbe. J'ai apporté de nouvelles connaissances sur la période de génération de
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47

Carlsson, Carina. "Neurotoxic Effects of Dichlorophenyl Methylsulphones Related to Olfactory Mucosal Lesions." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3463.

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Chery, Romain. "Plasticité de la dynamique spatiale et temporelle de la représentation d’une odeur dans le bulbe olfactif de souris." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA11T102.

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La représentation corticale des informations sensorielles est fondamentale dans la perception, la reconnaissance et la mémorisation des différents objets de l’environnement. Les mécanismes de codage d’un stimulus sensoriel au niveau d’une population neuronale prennent place dans le temps et l’espace, deux composantes que nous avons étudiées successivement dans ce travail de thèse. Dans le bulbe olfactif, la dynamique des activités neuronales se traduit par de larges oscillations du potentiel de champ local. Plusieurs études indiquent que ces activités oscillatoires varient en fonction de l’env
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49

Follert, Philipp. "Expression et fonction des microARN dans la neutrogenèse du bulbe olfactif." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM4083.

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Le bulbe olfactif (BO) des mammifères adultes est le siège d'une intense neurogenèse tout au long de la vie. L'intégration des nouveaux neurones dans le BO est alimentée par la génération continuelle de progéniteurs immatures dans la zone periventriculaire (ZPV) du ventricule latéral du cerveau antérieur. Au cours de leur différentiation, ceux-ci migrent « en chaine » de la ZPV vers le BO. Une fois dans le BO ils migrent alors radialement vers leur localisation finale et achèvent leur différentiation. Le phénotype des neurones néoformés est divers et est déterminé par la position des cellules
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50

Sultan, Sébastien. "Régulation par l’apprentissage de la neurogenèse adulte dans le bulbe olfactif et rôle des nouveaux neurones." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10014.

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Le bulbe olfactif est le siège d’une neurogenèse adulte permanente. Le nombre de nouveaux neurones issus de cette neurogenèse adulte est modulé par l’apprentissage, ce qui suggère un rôle des néoneurones dans la mémoire olfactive. Au cours de ce travail, nous avons montré que l’apprentissage olfactif associatif recrute des nouveaux neurones granulaires dans des régions de la couche granulaire du bulbe olfactif spécifiques à l’odeur apprise. Nous avons également mis en évidence un lien entre la force de l’apprentissage olfactif, sa rétention et la modulation de la neurogenèse qui en résulte. En
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