Literatura académica sobre el tema "Orchestration mechanisms"
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Artículos de revistas sobre el tema "Orchestration mechanisms"
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Lorenzo Ochoa, Oswaldo, Björn Claes, Oksana Koryak y Angel Diaz. "Integration through orchestration". Journal of Enterprise Information Management 30, n.º 4 (10 de julio de 2017): 555–82. http://dx.doi.org/10.1108/jeim-02-2016-0060.
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Purpose The purpose of this paper is to examine the mechanisms through which the use of enterprise systems (ESs) enhances buyer-supplier integration (BSI). More specifically, the authors explain a model where ES enhances BSI indirectly, mediated by inventory management capabilities (IMCs), as the way ES enhances BSI remains under-explored in the literature. Design/methodology/approach Application of the resource orchestration framework to explain how capabilities and mechanisms interplay to enhance BSI. Data were collected by means of a survey instrument. Data collection took place as part of a larger project, sponsored by the Spanish Government, to evaluate logistics competitiveness in Spain. Findings ES enhances BSI by serving as a coordinating mechanism that maintains capability configurations in a value-creating alignment. IMC plays a key, yet under-explored role as a mediating mechanism that supports ES-enabled BSI. Research limitations/implications First, this research does not fully capture the multi-party nature of the supply chain context. Second, data collection was limited to companies that were more likely to have a systematic approach to logistics issues (i.e. large- and medium-sized companies) and companies based in Spain. Originality/value This paper enhances both scholarly and practitioner understanding of the mechanisms through which the implementation and use of ES contributes to BSI. In addition, this paper integrates literature from different fields (e.g. strategy, information systems, and operations) to gain a better understanding of how the implementation and use of ES affects BSI.
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Mantovani, Alberto y Massimo Locati. "Orchestration of macrophage polarization". Blood 114, n.º 15 (8 de octubre de 2009): 3135–36. http://dx.doi.org/10.1182/blood-2009-07-231795.
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Nätti, Satu, Pia Hurmelinna-Laukkanen y Wesley J. Johnston. "Absorptive capacity and network orchestration in innovation communities – promoting service innovation". Journal of Business & Industrial Marketing 29, n.º 2 (28 de enero de 2014): 173–84. http://dx.doi.org/10.1108/jbim-08-2013-0167.
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Purpose – The purpose of this study is to increase understanding of service innovation in networks. Especially the most loosely coupled forms of innovation networks, innovation communities, can be valuable in service innovation, but may not be manageable in the traditional sense. Rather, they may require orchestration characterized by discreet guidance that also accommodates the specific nature of services. Through informed orchestration, it is possible to deal with several contingencies, and influence the absorptive capacity at the network level to generate new service innovations. Design/methodology/approach – These issues are examined through literature review and a case study. Findings – The findings suggest that individual orchestration mechanisms may be more closely connected to certain contingencies than others, and that both orchestration mechanisms and contingency factors have a role in absorptive capacity development within service innovation networks. Research limitations/implications – While the case study approach limits the possibility to make wide generalizations, the in-depth insights provide valuable knowledge. Practical implications – There has been a shift from inter-firm competition towards competition between networks of organizations, increasing relevance of absorptive capacity at the network level. Originality/value – Despite the recent increase in service innovation literature, research on service innovation taking place in networks is scant. Knowledge on some aspects can be derived from more traditional notions on technological innovation, but both the distinctive features of services and central characteristics of innovation networks make it necessary to reconsider some of the established views. In particular, managing – or rather orchestrating – service innovation is still a challenging area.
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Pan, Mei-Ren, Ming-Chuan Hsu, Li-Tzong Chen y Wen-Chun Hung. "Orchestration of H3K27 methylation: mechanisms and therapeutic implication". Cellular and Molecular Life Sciences 75, n.º 2 (17 de julio de 2017): 209–23. http://dx.doi.org/10.1007/s00018-017-2596-8.
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Schepis, Daniel, Sharon Purchase y Bella Butler. "Facilitating open innovation processes through network orchestration mechanisms". Industrial Marketing Management 93 (febrero de 2021): 270–80. http://dx.doi.org/10.1016/j.indmarman.2021.01.015.
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Santos, Juliana Bonomi, Laís Moltene, Vittoria Loviscek, Ely Laureano Paiva, Susana Carla Farias Pereira y Luiz Carlos Di Serio. "Orchestration coordination in innovation ecosystems: mechanisms and enabling factors". Academy of Management Proceedings 2021, n.º 1 (agosto de 2021): 15592. http://dx.doi.org/10.5465/ambpp.2021.15592abstract.
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NANDA, MANGALA GOWRI y NEERAN KARNIK. "SYNCHRONIZATION ANALYSIS FOR DECENTRALIZING COMPOSITE WEB SERVICES". International Journal of Cooperative Information Systems 13, n.º 01 (marzo de 2004): 91–119. http://dx.doi.org/10.1142/s0218843004000900.
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Web Services are emerging as the standard mechanism for making information and software available programmatically via the Internet, and as building blocks for applications. A composite web service may be built using multiple component web services. Once its specification has been developed, the composite service may be orchestrated either using a centralized engine or in a decentralized fashion. Decentralized orchestration brings performance benefits, and improves scalability and concurrency. Dynamic binding coupled with decentralized orchestration adds high availability and fault tolerance to the system. However in such systems, the coordination between components needs to be carefully designed to ensure correct execution of the composite and to limit the synchronization overheads. In this paper, we categorize different forms of concurrency and provide an algorithm to identify these forms in a composite service specification. We explore different mechanisms for transferring data between the components in the presence of different forms of concurrency. Then we experimentally evaluate the efficiency and scalability of each mechanism. We also analyze the coordination requirements of a decentralized orchestration in the presence of dynamic binding and fault propagation.
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Trakadas, Panagiotis, Panagiotis Karkazis, Helen C. Leligou, Theodore Zahariadis, Felipe Vicens, Arturo Zurita, Pol Alemany et al. "Comparison of Management and Orchestration Solutions for the 5G Era". Journal of Sensor and Actuator Networks 9, n.º 1 (4 de enero de 2020): 4. http://dx.doi.org/10.3390/jsan9010004.
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5G is considered to be the technology that will accommodate the development and management of innovative services with stringent and diverse requirements from end users, calling for new business models from the industry. In this context, the development and efficient management of Network Services (NS) serving specific vertical industries and spanning across multiple administrative domains and heterogeneous infrastructures is challenging. The main challenges regard the efficient provision of NSs considering the Quality of Service (QoS) requirements per vertical industry along with the optimal usage of the allocated resources. Towards addressing these challenges, this paper details an innovative approach that we have developed for managing and orchestrating such NSs, called SONATA, and compare it with OSM and Cloudify, which are two of the most known open-source Management and Orchestration (MANO) frameworks. In addition to examining the supported orchestration mechanisms per MANO framework, an evaluation of main operational and functional KPIs is provided based on experimentation using a real testbed. The final aim is the identification of their strong and weak points, and the assessment of their suitability for serving diverse vertical industry needs, including of course the Internet of Things (IoT) service ecosystem.
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Hu, Jingbo, Taohua Ouyang, William X. Wei y Jiawei Cai. "How Do Manufacturing Enterprises Construct E-Commerce Platforms for Sustainable Development? A Case Study of Resource Orchestration". Sustainability 12, n.º 16 (17 de agosto de 2020): 6640. http://dx.doi.org/10.3390/su12166640.
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The existing literatures mainly focus on the pricing, strategic significance and sustainable development characteristics of the e-commerce platform, and lack deep research on mechanisms in the process of construction like main structure of recourses and driving force. This paper takes Haier as a Chinese example and explores how manufacturing enterprises create and develop the sustainable e-commerce platform. The research findings show that: (1) An e-commerce platform respectively carries the functions of sales channels, service differences and innovation incubation in different stages of the manufacturing enterprises’ sustainable development; (2) For managing e-commerce platform of manufacturing enterprises’ sustainable development, resource orchestration can effectively realize the integration of value creation and resource; (3) Finally, it further reveals that the driving power which resource orchestration continuously promotes for the sustainable e-commerce platforms to construct is from the co-creation value of manufacturers and users. This paper discusses the structure of e-commerce platforms based on the main characteristics of each resource, and systematically explores the mechanism and evolutionary driving force of resource orchestration to promote the construction of e-commerce platforms for the sustainable development. It complements and enriches the innovation ecosystem and resource orchestration theory, providing significant practical guidance to the sustainable development of manufacturing enterprises.
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Kelleher, Carol, Deirdre O’Loughlin, Johanna Gummerus y Lisa Peñaloza. "Shifting Arrays of a Kaleidoscope: The Orchestration of Relational Value Cocreation in Service Systems". Journal of Service Research 23, n.º 2 (6 de noviembre de 2019): 211–28. http://dx.doi.org/10.1177/1094670519882495.
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The predominant value discourse among scholars characterizes value cocreation as involving multiple actors at the micro-, meso-, and macrolevels in service systems. This research contributes to the knowledge of the interdependencies among multiple resource-integrating actors and value outcomes by employing a relational perspective on value cocreation within the empirical context of family caregiving. The findings reveal how interdependent actors orchestrate value cocreation in service systems, how this impacts value, and how orchestration precipitates system adjustments, which form the recursive context of value cocreation over time. We differentiate and delineate three multi-actor orchestration mechanisms— assembling, performing, and brokering—through which nonreferent beneficiaries coordinate value cocreation on behalf of dependent referent beneficiaries. We term the mutually generalized oscillating multiform negative and positive well-being outcomes that emerge from orchestration among interdependent actors as relational value. In employing the metaphor of the kaleidoscope to emphasize system dynamism, our discussion of relational value cocreation deepens our understanding of how nonreferent beneficiary-led orchestration, founded on generalized mutuality and on behalf of referent beneficiaries with reduced agency, enhances and balances multiform, oscillating and positive and negative well-being outcomes in service systems. This will help service practitioners facilitate orchestration and optimize value for all.
Tesis sobre el tema "Orchestration mechanisms"
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Tkachuk, Roman-Valentyn. "Towards Decentralized Orchestration of Next-generation Cloud Infrastructures". Licentiate thesis, Blekinge Tekniska Högskola, Institutionen för datavetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-21345.
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Cloud Computing helps to efficiently utilize the abundance of computing resources in large data centers. It enables interested parties to deploy their services in data centers while the hardware infrastructure is maintained by the cloud provider. Cloud computing is interesting in particular as it enables automation of service deployment and management processes. However, the more complex the service structure becomes, the more complex deployment and management automation of all its parts can become. To this end, the concept of service orchestration is introduced to streamline service deployment and management processes. Orchestration enables the definition and execution of complex automation workflows targeted to provision computing infrastructure, deploy needed service features, and provide management support. In particular, the orchestration process enables the deployment and enforcement of security and compliance mechanisms in the context of systems where sensitive data is being processed. This thesis investigates the orchestration process as a uniform approach to deploy and manage network services and required security and compliance mechanisms. To this end, we investigate different use-cases where the orchestration process is applied to address specific requirements towards security and compliance. This thesis includes two parts. In the first part, we focus on centralized orchestration mechanisms, where all activities are performed from one trusted server. We explore the use-cases of a security testbed and collaborative AI engineering and investigate the advantages and limitations of orchestration mechanisms application in their context. In the second part, we shift towards the investigation of decentralized orchestration mechanisms. We employ blockchain technology as the main decentralization mechanism, exploring the advantages and limitations of its application in the context of digital marketplaces. We demonstrate that the shift towards blockchain-enabled orchestration enables the deployment and management of decentralized security mechanisms, ensuring compliant behavior of digital marketplace actors.
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Pérez, Sanagustín Maria del Mar. "Operationalization of collaborative blended learning scripts: a model, computational mechanisms and experiments". Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/38360.
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Portable and interactive technologies are changing the nature of collaborative learning practices. Learning can now occur both in and beyond the classroom and furthermore combine formal and informal activities monitored and orchestrated across spatial locations. This rises to a new type of orchestrated learning that we term Computer Supported Collaborative Blended Learning (CSCBL) scripts. This thesis investigates the challenges associated with the design of CSCBL scripts and with the technologies responsible for their enactment. Three contributions are presented. First, a conceptual model that combines 4 factors to be considered in the design of CSCBL scripts. Second, technological solutions operationalizing the aforementioned factors are proposed and evaluated through synthetic experiences. And third, four CSCBL experiments using 4SPPIces. These experiments are analyzed into two interrelated multicase case studies, whose cross-analyzed results provide an evaluation of the model, of the operationalization solutions supporting the enactment of the involved CSCBL scripts and of the educational value of the experiences themselves.La introducción de tecnologías interactivas y móviles está produciendo un cambio significativo en la naturaleza de las prácticas educativas. Actualmente, el aprendizaje mediante colaboración se puede dar en situaciones en que secuencias de actividades formales e informales dentro y fuera del aula se combinan e integran de forma coordinada. Esto da lugar a un nuevo tipo de actividades de colaboración orquestadas en entornos mezclados que llamaremos guiones CSCBL (de su acrónimo en inglés). Esta tesis investiga los retos relacionados con diseño de los guiones CSCBL y de la selección apropiada de la tecnología para su puesta en marcha. De este trabajo de investigación se derivan tres contribuciones principales. Primero, se propone un modelo conceptual que combina 4 factores a tener en cuenta en el diseño de guiones CSCBL. Segundo, se proponen un conjunto de soluciones tecnológicas para dar soporte computacional a los diferentes factores del modelo y dar apoyo a la puesta en marcha de guiones CSCBL. Cada una de estas soluciones se evalúa mediante experimentos sintéticos. Finalmente, esta tesis presenta tres experimentos en que se usa el modelo para proponer actividades de colaboración en entornos mezclados y aplicarlas en entornos reales. Estos experimentos han sido evaluados mediante dos estudios múltiples de casos. El análisis cruzado de los resultados de los casos englobados en cada estudio ofrece una evaluación de la utilidad del modelo y de las soluciones tecnológicas adoptadas para su puesta en marcha.
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Fernandes, Pereira Sonia y Nejat Hamid. "Closed-Loop Orchestration Solution". Thesis, KTH, Hälsoinformatik och logistik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-253005.
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Computer networks are continuously evolving and growing in size and complexity. New technologies are being introduced which further increases the complexity. Net- work Service Orchestration is all about pushing configuration out into the network devices automatically without human intervention. There can be issues that causes the orchestration to fail. In many cases manual operations must be done to recover from the error which is very contradicting since the goal of orchestration is that it should be fully automated. There is some indication that the errors that are being solved manually could be de- tected and handled by a feedback mechanism. This thesis work aimed to build on current insight and if possible, verify that the feedback mechanism is a viable method. After consideration on different ways to solve the research question, the choice fell on creating a test environment where the approach was tested. The test environment was used to investigate if a network orchestration system could be integrated with a feedback mechanism. The result of this project presents a way to automatically de- tect a network failure and send feedback to a Network Service Orchestrator. The or- chestrator is then able to identify and correct the error.Datornätverk utvecklas kontinuerligt och växer i storlek och komplexitet. Nyteknik införs som ytterligare ökar komplexiteten. Nätverksservice orkestrering handlar om att skicka ut konfiguration automatiskt till enheter i nätverket utan mänsklig in- blandning. Det kan finnas problem som gör att orkestreringen misslyckas. I många fall måste manuella åtgärder utföras för att lösa problemet, vilket är mycket motsä- gelsefullt, eftersom målet med orkestrering är att det ska vara fullt automatiserat. Det finns indikationer på att fel kan detekteras och hanteras av en återkopplings- mekanismen. Detta examensarbete syftar till att bygga på aktuell insikt, och om möj- ligt, verifiera att återkopplingsmekanismen är en möjlig metod. Efter överväganden på vilka olika sätt som projektmålet kunde uppnås föll valet på att skapa en testmiljö där ansatsen kunde testas. Testmiljön användes för att utreda om ett nätverksorkestreringssystem kan integreras med en återkopplings mekanism. Resultat av projektet presenterar ett sätt att automatiskt upptäcka ett nätverksfel och skicka återkoppling till ett nätverksorkestreringssystem. Nätverksorkestreraren kan sedan detektera och åtgärda felet.
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Roig, Puiggros Sergi. "Molecular mechanisms orchestrating commissural axon guidance Floor-plate-derived netrin-1 is dispensable for commissural axon guidance Synergistic Activity of Floor-Plateand Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance". Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS335.
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Les neurones commissuraux assurent la coordination des informations motrices et somatosensorielles entre les deux moitiés du système nerveux central. Dans la partie caudale du SNC, les axones commissuraux migrent d'abord vers la ligne médiane ventrale, la plaque du plancher, pour la traverser et puis atteindre leur cible finale. Les mécanismes cellulaires et moléculaires qui contrôlent le croisement de la ligne médiane ont fait l'objet d'Etudes approfondies. Ramón y Cajal, dans sa théorie neurotrophique, a suggéré que les cellules de la plaque de plancher pourraient libérer des facteurs diffusibles qui attirent les axones commissuraux vers la ligne médiane ventrale. La nétrine-1, une protéine découverte il y a plus de deux décennies, est une protéine secrétée exprimée à la fois par les cellules de la plaque de plancher et les progéniteurs de la zone ventriculaire et possède une activité chimioattractive à longue distance in vitro. Aujourd'hui, la nétrine-1 est largement acceptée comme l'exemple parfait de la chimioattraction à longue distance. Cependant, nos résultats remettent en question ce modèle, proposant un mécanisme d'action à courte portée de nétrine-1 pendant le guidage des axones commissuraux. En effet, nous avons déterminé que la nÉtrine-1 dérivée de la plaque du plancher n'est pas nécessaire pour le guidage des axones commissuraux. C’est la nétrine-1 dérivée de la zone ventriculaire qui est nécessaire et suffisante pour induire la migration dorso-ventrale des axones commissuraux du cerveau postérieur et leur croisement de la ligne médiane. Nous avons Également confirmé que les progéniteurs de la zone ventriculaire sont la principale source de Netrin-1 pour la migration ventrale des neurones précérébelleux. De plus, nous observons qu'en l'absence de nétrine-1 dérivée de la zone ventriculaire, les axones commissuraux et les neurones précérébelleux envahissent plusieurs nerfs crâniens. Il s’agit d'un procès autonome et dépendant de Dcc. A différence du tronc cérébral, dans la moelle épinière, les deux sources de nétrine-1 agissent en synergie pour assurer le guidage des axones commissuraux et le croisement des lignes médianes. Les neurones commissuraux sont une population diverse distribuée tout au long du système nerveux. Pour analyser la diversité moléculaire des neurones commissuraux du cerveau postérieur et de la moelle épinière, nous avons utilisé des approches combinant la génétique de la souris et la transcriptomique. Nous travaillons actuellement sur de nouveaux facteurs de transcription qui pourraient jouer un rôle dans le développement des neurones commissuraux du tronc et de la moelle épinièreCommissural neurons ensure the coordination of motor and somatosensory information between halves of the central nervous system. In the caudal part of the CNS, commissural axons, first grow toward the ventral midline, the floor plate, to cross it and reach their final target. The cellular and molecular mechanisms controlling midline crossing have been extensively studied. Ram—n y Cajal, in his neurotropic theory, suggested that floor plate cells could release diffusible factors chemo-attracting commissural axons to the ventral midline. Netrin-1, a protein discovered more than 2 decades ago, is a secreted protein expressed both by floor plate cells and ventricular zone progenitors and with long-range chemoattractive activity in vitro. Today, Netrin-1 is widely accepted as the textbook example of long-range chemoattractive guidance cue. However, our results, challenge this model by proposing a short-range mechanism of action for Netrin-1 during commissural axon guidance. Indeed, we determined that floor plate-derived netrin-1 is dispensable for commissural axon guidance. Instead, ventricular zone-derived netrin-1 is necessary and sufficient to promote the dorso-ventral extension of hindbrain commissural axons and midline crossing. We also confirmed that ventricular zone progenitors are the main Netrin-1 source for ventrally migrating precerebellar neurons. In addition, we observe that in absence of ventricular zone-derived netrin-1, commissural axons and precerebellar neurons cell bodies invade several cranial nerves. This appears to be a cell- autonomous and Dcc-dependent process. This mechanism is not conserved in the spinal cord, where both netrin-1 sources act synergistically to ensure commissural axon guidance and midline crossing. Commissural neurons are diverse and found throughout the nervous system. To analyse the molecular diversity of hindbrain and spinal cord commissural neurons, we used approaches combining mouse genetics and transcriptomics. We are currently working on some novel transcription factors that might play a role in the development of hindbrain and spinal cord commissural neurons
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Bartashevich, Dzianis. "Orchestration of cloud services with critical components in SKA". Master's thesis, 2019. http://hdl.handle.net/10773/29552.
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This dissertation proposes methods of high-availability for critical applications
to maintain their normal function and recover from unexpected failures. Applications
can be developed and deployed to work within the cloud environment
to achieve flexibility in maintenance, also giving the option of monitorization. A
monitoring system can monitor system metrics like CPU usage or just a specific
application service, whether is it running. Additionally, creating alarms
within the monitoring system, allowing to trigger notification upon a failure
event occurrence helping the orchestrator to failover. The failure occurrence
can happen when a certain metric is above the established threshold where
the Service Level Agreement (SLA) is violated. The implemented and tested
solution uses OpenStack private cloud as infrastructure support, and through
use of the Heat orchestrator, TICK stack monitoring system, and a recovery
engine provided with a capable solution for critical application monitoring, providing
high-availability. The test results proved the solution worth in different
test scenarios indicating monitoring limits of the system and showed the service
recovery time to be reasonable without compromising other services.Esta dissertação propõe métodos de alta disponibilidade para aplicações críticas, a fim de manter a sua função normal e se recuperar de falhas inesperadas. As aplicações podem ser desenvolvidas e alojadas para trabalhar no ambiente de nuvem para obter flexibilidade na manutenção, oferecendo também a opção de monitorização. Um sistema de monitorização pode vigiar as métricas do sistema, como o uso de CPU ou apenas um serviço de aplicativo específico, esteja ele em execução ou não. Além disso, a criação de alarmes no sistema de monitorização permite acionar a notificação sobre uma ocorrência não esperada de evento, ajudando o orquestrador a recuperar a situação do estado critico. A ocorrência da falha pode acontecer quando uma determinada métrica está acima do limite estabelecido, onde o SLA (Service Level Agreement) é violado. A solução implementada e testada usa a nuvem privada OpenStack como suporte à infraestrutura e, por meio do orquestrador Heat, do sistema de monitorização TICK Stack e de um mecanismo de recuperação, fornece uma solução capaz para o monitorizar o estado das aplicações, oferecendo alta disponibilidade. Os resultados do teste provaram que a solução é capaz de recuperar o serviço em diferentes cenários de teste, indicando os limites de monitorização do sistema e recuperar o serviço em tempo aceitável sem comprometer outros serviços.
Mestrado em Engenharia Informática
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Marques, Filipa Carvalhal. "Mechanisms of aging: neuronal orchestration of stress resistance and protein homeostasis in the nematode Caenorhabditis elegans". Doctoral thesis, 2016. http://hdl.handle.net/10316/29393.
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Tese de doutoramento em Ciências da Saúde, no ramo de Ciências Biomédicas, apresentada à Faculdade de Medicina da Universidade de CoimbraO envelhecimento é um processo complexo que ocorre em todos os organismos, da levedura ao Homem. Apesar de um século de pesquisa e discussão científica, os factores subjacentes à progressão do envelhecimento permanecem por clarificar. Mas os ângulos sob os quais este processo é visto sofreram grandes mudanças com o tempo. As primeiras teorias sugeriam que o envelhecimento decorre da acumulação estocástica de danos nas macromoléculas, levando ao mal funcionamento dos organismos e, por fim, à morte dos mesmos. Esta área de investigação foi radicalmente transformada nas últimas décadas por uma série de estudos pioneiros em diferentes modelos animais que mostraram claramente que o envelhecimento pode ser alterado através da manipulação de várias vias metabólicas e genéticas. Estas descobertas sugeriram que o nível de protecção de um organismo contra danos estocásticos pode ser regulado e, consequentemente, também o período de vida durante o qual o mesmo permanece saudável. No entanto, à medida que o conhecimento acerca destes mecanismos foi maturando, tornou-se evidente que a duração de vida, a resistência a stress e a homeostase proteica, aspectos que são regulados pelas vias que regulam o envelhecimento, podem ser desacopladas sem se influenciarem mutuamente. Mais recentemente, o processo de envelhecimento revelou possuir um nível adicional de complexidade quando se mostrou que pode ser coordenado por diferentes tecidos ao nível do organismo. Neste trabalho, o nosso interesse focou-se nos princípios subjacentes à orquestração do envelhecimento ao nível do organismo, bem como na dissociação entre duração de vida, resistência a stress e homeostase proteica. De modo a abordar estes temas, usámos o nemátode Caenorhabditis elegans (C. elegans), modelo animal que oferece inúmeras vantagens no estudo do envelhecimento. Começámos por investigar os mecanismos de comunicação entre tecidos que regulam a heat shock response (HSR) a nível do organismo no modelo C. elegans, procurando, mais concretamente, esclarecer que receptores neuronais estão envolvidos neste mecanismo de sinalização e em que neurónios desempenham a sua função. Para responder a estas questões, empregámos nemátodes geneticamente modificados que apresentam hipersensibilidade a RNA de interferência (RNAi) no tecido nervoso e identificámos um presumível receptor acoplado a proteínas G (GPCR) como sendo um componente-chave deste mecanismo. Este gene, a que atribuímos o nome gtr-1, é expresso em neurónios quimiosensoriais e desempenha um papel fundamental na indução de genes que codificam proteínas de heat shock nos tecidos somáticos após exposição a temperaturas elevadas, apesar de não ser necessário à percepção de calor. Surpreendentemente, o knockdown do gtr-1 através de RNAi tem um efeito protector em nemátodes que expressam nos músculos Aβ3-42 (um péptido com tendência agregativa associado à doença de Alzheimer), mas não influencia a duração de vida, a resistência a outros stresses ou funções associadas ao desenvolvimento. Na segunda parte deste trabalho pretendemos fazer uma caracterização mais detalhada dos elementos downstream à via de sinalização da insulina/IGF-1 (IIS) que estão directamente envolvidos na regulação da toxicidade proteica em C. elegans. Com este objectivo, procurámos genes previamente citados na literatura como reguladores da homeostase proteica e identificámos o tor-2 como sendo regulado ao nível da transcrição pela via IIS. Nesta tese mostramos que a expressão do tor-2 é induzida após a supressão desta via pelos factores de transcrição DAF-16 e SKN-1. Este gene revelou-se importante na resistência a temperaturas elevadas mas não na regulação do tempo de vida do animal ou na resistência a outros tipos de stress tais como exposição a bactérias patogénicas ou a radiação UV. Curiosamente, o tor-2 parece ser importante no combate à toxicidade proteica em neurónios, onde se mostrou anteriormente que este gene é expresso, ao passo que o seu knockdown protege os nemátodes que expressam proteínas agregativas tóxicas nos músculos. Este estudo oferece novas ideias: (1) que os neurónios quimiosensoriais desempenham um papel importante nos mecanismos que regulam a HSR no nemátode; (2) que o tempo de vida e a resistência a heat shock são separáveis; (3) consolida o conceito emergente de que a habilidade para responder o calor existe em detrimento da manutenção da proteostase; e (4) sugere que a homeostase proteica pode ser diferencialmente regulada de tecido para tecido por um único gene.
Aging is a complex process that occurs in organisms ranging from yeast to humans. The factors underlying the progression of aging still elude us, despite a century of scientific inquiry and discussion. Nevertheless, the angles from which aging was perceived have greatly changed over time. Early theories suggested that aging results from the accumulation of stochastic damage to macromolecules, leading to organismal malfunction and ultimately death. The field was however revolutionized over the last decades by a series of pioneering studies carried out in model organisms that showed that aging can actually be altered by the modification of several metabolic and genetic pathways. These findings suggested that the level of protection against stochastic damage can be regulated and, hence, the length of time an organism remains healthy. However, as the knowledge on these mechanisms matured, it became evident that lifespan, stress resistance, and protein homeostasis (proteostasis), aspects that are regulated by the aging-modulating pathways, can be uncoupled without influencing one another. The aging process revealed another level of complexity when it was shown to be coordinated by different tissues in an organismal-fashion. In this work, we were interested in the principles underlying the orchestration of aging at the organismal level, as well as in the uncoupling between lifespan, stress resistance, and proteostasis. To address these questions, we employed the nematode Caenorhabditis elegans (C. elegans), which offers key advantages in the study of aging. We started by focusing on the inter-tissue communication mechanisms that regulate the heat shock response (HSR) at the organismal level in C. elegans and attempted to clarify which neuronal receptors are required for this signaling mechanism and in which neurons they function. To answer these questions, we employed worms that were engineered to exhibit RNA interference (RNAi) hypersensitivity in neurons and identified a putative G protein-coupled receptor (GPCR) as a novel key component of this mechanism. This gene, which we termed GPCR thermal receptor 1 (gtr-1), is expressed in chemosensory neurons and has no role in heat sensing but is critically required for the induction of genes that encode heat shock proteins in non-neural tissues upon exposure to heat. Surprisingly, the knockdown of gtr-1 by RNAi protected worms expressing the Alzheimer's-disease-linked aggregative peptide Aβ3-42 in their body-wall muscles from protein toxicity (proteotoxicity) but had no effect on lifespan, resistance to other stresses, or developmental functions. In the second part, we aimed at better characterizing the insulin/IGF-1 signaling (IIS)-downstream components involved in the direct regulation of protein toxicity (proteotoxicity) in the C. elegans model. For this, we searched for genes that are known regulators of proteostasis and identified tor-2 as a transcriptional target of the IIS pathway. Here we show that tor-2 is upregulated upon suppression of the IIS by both DAF-16 and SKN-1transcription factors. This gene is important for the resistance to heat shock but has no role in the determination of lifespan or in the resistance to other acute stresses such as exposure to pathogenic bacteria or to UV radiation. Interestingly, tor-2 seems to be important to counteract proteotoxicity in neurons, previously shown to be its main site of expression, whereas its knockdown protects worms that express toxic, aggregative-proteins in their body-wall muscles. In this work we provide several novel insights: (1) we show that chemosensory neurons play important roles in the nematode's HSR-regulating mechanism; (2) that lifespan and heat stress resistance are separable; (3) we strengthen the emerging notion that the ability to respond to heat comes at the expense of proteostasis; and (4) suggest that proteostasis can be differentially regulated in a tissue-specific manner by a sole gene.
FCT - SFRH/BD/70502/2010
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Castro, Karima Daniela Velasquez. "Mechanisms for Latency Reduction in Fog Environments". Doctoral thesis, 2021. http://hdl.handle.net/10316/95282.
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N/ATese no âmbito do Programa de Doutoramento em Ciências e Tecnologias da Informação, apresentada ao Departamento de Engenharia Informática da Faculdade de Ciências e Tecnologia da Universidade de Coimbra.
A new industrial revolution driven by digital data, computation, and automation has arrived. Human activities, industrial processes, and research lead to data collection, generation, and processing on an unprecedented scale, spurring new products, services, and applications. Among the applications that generate more traffic are those related to augmented/virtual reality and video streaming. These applications have strict time restrictions to perform in a manner that is expected by final users, and usually rely on the use of Cloud computing to achieve elasticity, on-demand self-service, resource pooling, and timely delivery. However, new generation delay-sensitive applications and services have requirements that are only partially met by existing Cloud computing solutions. In recent years there has been a paradigm shift to bring Cloud services towards the edge of the network. In this peripheral area, there is an abundance of heterogeneous resource-constrained devices both generating and consuming data. This represents an increment on the amount of data, that would lead to increased traffic and response time to transport to the Cloud and back. It is possible to place storage and processing devices at the rim of the network to help preprocess this data and alleviate the load sent towards the core network, while also reducing response times which benefits delay-sensitive applications particularly. This solution is known as Fog computing. Fog computing is an important paradigm to help address the requirements that are not completely covered by the Cloud; nonetheless, the use of this technology creates new challenges. The Fog needs to support the orchestration of applications and services on demand, with adaptability, while providing flexible and time constrained performance. In practice, traditional service orchestration approaches that were applied to Cloud services are not suitable for the large scale and dynamism of Fog services. This creates the need for new mechanisms for the coordination of resources, applications, and services in the Fog. This work proposes a smart orchestration framework based on a hybrid approach that combines centralized orchestration and distributed choreography to deal with resource management, as well as a service orchestrator architecture that includes a depiction of its different modules and the interactions among them. To cope with the time constraints for delay-sensitive applications, the orchestrator must optimize where applications and services are deployed. One of the modules of the service orchestrator architecture proposed in this work is in charge of the decision regarding the final placement of application services in a smart and context-aware manner with the objective of minimizing latency. Particularly, this work presents three different mechanisms for service placement in the Fog ecosystem, namely, one based in Integer Linear Programming, one based in Genetic Algorithms, and one based in graph partition using the PageRank algorithm. All three mechanisms use a combination of metrics that evaluate characteristics of both the applications as well as the network infrastructure to guide the placement process. From the network perspective, the propagation delay is considered; and from the application perspective, the popularity of the applications (measured by the amount of requests) is used. This approach, unlike any previous work, leads to the prioritization of popular applications during the placement process, thus benefiting a larger number of final users. The mechanisms are tested via simulation under different scenarios and conditions. The experiments show that it is possible to provide lower latency to popular applications while also reducing the latency of the overall system. Furthermore, for dynamic scenarios, a profiling scheme based on application popularity allowed to reduce not only the latency but also the jitter for popular applications.
Estamos perante uma nova revolução industrial impulsionada por dados digitais, computação e automação. A atividade humana, processos industriais e investigação levam à recolha, geração e processamento de dados numa escala sem precedentes, fomentando novos produtos, serviços e aplicações. Entre as aplicações que geram mais tráfego, estão as aplicações relacionadas com realidade aumentada/virtual e transmissão de vídeo. Estas aplicações têm restrições temporais estritas para serem executadas de acordo com o esperado pelo utilizador final e, geralmente, recorrem ao uso de computação em Nuvem para alcançar elasticidade, serviços a pedido do utilizador, agrupamento de recursos e entrega atempada. No entanto, a nova geração de aplicações e serviços sensíveis a atraso tem requisitos que são apenas parcialmente cumpridos pelas soluções de computação em Nuvem existentes. Recentemente, tem havido uma mudança de paradigma no sentido de trazer os serviços da Nuvem para a perímetro da rede. Nesta área periférica existe uma abundância de dispositivos heterogéneos com recursos limitados tanto na geração como no consumo de dados. Este cenário representa um aumento na quantidade de dados, que leva ao aumento do tráfego e do tempo de resposta nas comunicações de, e para, a Nuvem. No sentido de ajudar o pré-processamento destes dados e aliviar a carga enviada através da rede, é possível mudar os dispositivos de armazenamento e processamento para a extremidade da rede, reduzindo os tempos de resposta e beneficiando, particularmente, as aplicações sensíveis a atraso. Esta solução é conhecida como computação em Nevoeiro. A computação em Nevoeiro é um paradigma importante que ajuda a satisfazer os requisitos que não são totalmente cobertos pela Nuvem; no entanto, o uso desta tecnologia cria novos desafios. O Nevoeiro necessita de suportar a orquestração de aplicações e serviços disponíveis a pedido do utilizador, com adaptabilidade, e garantindo uma performance flexível e cumpridora das restrições temporais. Na prática, as abordagens tradicionais de orquestração de serviços aplicadas aos serviços em Nuvem não são adequadas para a larga escala e dinamismo dos serviços de Nevoeiro. Assim, existe a necessidade de novos mecanismos para a coordenação de recursos, aplicações e serviços de Nevoeiro. Este trabalho propõe uma framework de orquestração inteligente baseada numa abordagem híbrida que combina orquestração centralizada e coreografia distribuída para lidar com a gestão de recursos e, ainda, uma arquitetura para um orquestrador de serviços que inclui uma representação dos seus diferentes módulos e respetivas interações. Para lidar com as restrições temporais das aplicações sensíveis a atraso, o orquestrador deve otimizar onde colocar as aplicações e serviços. Um dos módulos da arquitetura do orquestrador de serviços proposto neste trabalho é encarregue da decisão da colocação final dos serviços da aplicação de modo inteligente e consciente de contexto com o objetivo de minimizar a latência. Este trabalho apresenta três mecanismos para a colocação de serviços no ecossistema de Nevoeiro, nomeadamente, um baseado em programação linear inteira, um baseado em algoritmos genéticos e um baseado em partição de grafos, utilizando o algoritmo PageRank. Todos os mecanismos usam uma combinação de métricas que avalia as características tanto das aplicações como da infraestrutura da rede e que guia o processo de colocação. Da perspetiva da rede, é considerado o tempo de propagação; da perspetiva da aplicação, é utilizada a popularidade das aplicações, medida pela quantidade de pedidos. Esta abordagem, contrariamente aos trabalhos anteriores, leva à priorização das aplicações populares durante o processo de colocação e, consequentemente, beneficia um maior número de utilizadores finais. Os mecanismos são testados via simulação com diferentes cenários e condições. Os resultados mostram que é possível obter uma latência menor para aplicações populares e, simultaneamente, reduzir a latência geral do sistema. Além disso, em cenários dinâmicos, um esquema de perfil baseado na popularidade das aplicações permitiu reduzir não só a latência, como também a variação de atraso das aplicações populares.
N/A
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Chiu, Yih-Jye y 邱義傑. "Investigation and Enhancement of CORD-XOS Orchestration Mechanism". Thesis, 2018. http://ndltd.ncl.edu.tw/handle/xfkemd.
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Lai, Kuan-Hung y 賴冠宏. "An Adaptive Resource Orchestration Mechanism for Cognitive Radio Networks". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/ygfv2p.
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碩士國立臺灣科技大學
電機工程系
106
With fast development of wireless network technology, networking functions have become the basic of all kinds of equipment. However, with the rapid growth of network devices, the usage of transmission resources by end devices and wireless access point (AP) is often lack of immediate and proper configuration in traditional wireless architecture. Therefore, how to regulate the wireless transmission resource flexibly to respond with the interference such as the surrounding change and resource contention is an important issue. This study propose an adaptive resource orchestration system in wireless LAN which is based on the operation concept of cognitive radio technology. By collecting the environmental parameters, including the retransmission rate and the channel occupied rate, this system could have knowledge of the overall transmission behavior and regulate the transmission resource and at the right moment. For end devices, there is an adaptive connection assignment (ACA) mechanism designed to filter the target end device with worse transmission performance, analyze its alternative AP availability and ask it to change the connection for better transmission performance. For APs, there is an adaptive channel utilization (ACU) mechanism designed to find out the target AP which is under the interference, analyze its alternative channel availability and ask it to change its working channel for better transmission efficiency. In order to confirm the work of proposed system and mechanisms, there are four simulation scenarios designed. From the result of simulations in different scenarios, the throughput of end devices could be raise 15 to 24%, the throughput of APs could increase 6 to 47% and the retransmission rate of APs could reduce 0.4 to 5.3%.
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Lai, Wen-Ping y 賴文蘋. "Design and Implementation of Media Servers : A Synchronization Management Mechanism for Supporting Media Orchestration in Synthetic Documents". Thesis, 2001. http://ndltd.ncl.edu.tw/handle/98134999698864360667.
Texto completoCapítulos de libros sobre el tema "Orchestration mechanisms"
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Gutiérrez Rojas, Israel, Raquel M. Crespo García y Carlos Delgado Kloos. "Enhancing Orchestration of Lab Sessions by Means of Awareness Mechanisms". En Lecture Notes in Computer Science, 113–25. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-33263-0_10.
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Mantovani, Alberto, Cecilia Garlanda y Barbara Bottazzi. "Pentraxins in the Orchestration of Defense and Tissue Repair during the Acute Phase Response". En Inflammation - From Molecular and Cellular Mechanisms to the Clinic, 1347–62. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527692156.ch53.
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Pichler, Horst, Michaela Wenger y Johann Eder. "Composing Time-Aware Web Service Orchestrations". En Notes on Numerical Fluid Mechanics and Multidisciplinary Design, 349–63. Cham: Springer International Publishing, 2009. http://dx.doi.org/10.1007/978-3-642-02144-2_29.
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Darby, Ian A. y Alexis Desmoulière. "Scar Formation: Cellular Mechanisms". En Textbook on Scar Management, 19–26. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_3.
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AbstractFibroblasts are key players in the maintenance of skin homeostasis and in orchestrating physiological tissue repair. Fibroblasts secrete and are embedded in a sophisticated extracellular matrix, and a complex and interactive dialogue exists between fibroblasts and their microenvironment. In addition to the secretion of the extracellular matrix, fibroblasts and myofibroblasts secrete extracellular matrix remodeling enzymes, matrix metalloproteinases and their inhibitors, and tissue inhibitors of metalloproteinases and are thus able to remodel the extracellular matrix. Myofibroblasts and their microenvironment form a network that evolves during tissue repair. This network has reciprocal actions affecting cell differentiation, cell proliferation, cell quiescence, or apoptosis and has actions on growth factor bioavailability by binding, sequestration, and activation. Mechanical forces also play a role in regulating the myofibroblast phenotype as cells are subjected to mechanical stress and mechanical signaling is activated. Innervation is also involved in both skin repair processes and differentiation of myofibroblasts. In pathological situations, for example, in excessive scarring, the dialogue between myofibroblasts and their microenvironment can be altered or disrupted, leading to defects in tissue repair or to pathological scarring, such as that seen in hypertrophic scars. Better understanding of the intimate dialogue between myofibroblasts and their local microenvironment is needed and will be important in aiding the identification of new therapeutic targets and discovery of new drugs to treat or prevent aberrant tissue repair and scarring.
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Gupta, Reena, Raj Kamal y Ugrasen Suman. "Designing of an Orchestration Mechanism for the Efficient Web-Services Composition". En Advances in Intelligent Systems and Computing, 171–82. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7871-2_17.
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Taylor, Jennifer M. y Greg J. Neimeyer. "Continuing Education and Lifelong Learning Strategies". En Handbook of Private Practice, 602–19. Oxford University Press, 2017. http://dx.doi.org/10.1093/med:psych/9780190272166.003.0046.
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The goal of this chapter is to facilitate effective lifelong learning and continuing professional competence. The authors discuss lifelong learning, the issues at stake with continuing education, the multiple functions it is designed to fill, and challenges faced with the current mechanisms designed to fulfill these functions and objectives. The authors encourage the thoughtful utilization and orchestration of these mechanisms to maximize the utility of continuing education and training in the development and maintenance of professional competence. The chapter reviews the issues involved in continuing education, outlines its purposes, discusses outcomes, and anticipates the rapidly developing trends in the field. The authors’ hope is that this chapter will contribute to a “road map” that will help support more effective lifelong learning and continuing professional development for mental health professionals.
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Wettinger, Johannes, Tobias Binz, Uwe Breitenbücher, Oliver Kopp y Frank Leymann. "Streamlining Cloud Management Automation by Unifying the Invocation of Scripts and Services Based on TOSCA". En Cloud Technology, 2240–61. IGI Global, 2015. http://dx.doi.org/10.4018/978-1-4666-6539-2.ch106.
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Today, there is a huge variety of script-centric approaches, APIs, and tools available to implement automated provisioning, deployment, and management of applications in the Cloud. The automation of all these aspects is key for reducing costs. However, most of these approaches are script-centric and provide proprietary solutions employing different invocation mechanisms, interfaces, and state models. Moreover, most Cloud providers offer proprietary APIs to be used for provisioning and management purposes. Consequently, it is hard to create deployment and management plans that integrate multiple of these approaches. The goal of the authors work is to come up with an approach for unifying the invocation of scripts and services without handling each proprietary interface separately. A prototype realizes the presented approach in a standards-based manner using the Topology and Orchestration Specification for Cloud Applications (TOSCA).
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Gamlen, Alan. "Orchestrating a Migration Regime". En Human Geopolitics, 205–27. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198833499.003.0009.
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Chapter 9 shows how the widespread adoption of diaspora institution models and best practices has been orchestrated by international organizations, and supported by the actions of a ‘diaspora engagement industry’ of professional consultants, think tanks, and NGOs working on the topic. The chapter shows how and why key international organizations consumed and assimilated models of diaspora engagement, and how they ‘orchestrated’ the dissemination of these policy models and best practices to states around the world. The discussion also highlights how international organizations have used mechanisms such as ‘donor menus’ to retain credibility as disinterested experts, and also how such mechanisms have concealed the role of powerful donor state interests in shaping this supposedly disinterested advice.
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Najmaei, Arash. "Business Model". En Strategic and Pragmatic E-Business, 100–131. IGI Global, 2012. http://dx.doi.org/10.4018/978-1-4666-1619-6.ch005.
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Today’s world of business is increasingly witnessing exemplary firms which introduce new business models, exploit new markets and disrupt established firms in order to create a unique competitive position. Although the theoretical and conceptual posture of this phenomenon is well grounded and explained in the extant literature on disruptive innovation, little is known about strategic logic of this phenomenon. In other words, the managerial paradigm or cognitive and mental model that underlies the orchestration of micro- and macro-organizational mechanisms of a disruptive move, such as market and technological knowledge, have surprisingly received little attention. In this sense, an analytical review of literature suggests that strategic logic of a disruptive technology can be well presented through the lens of business model (BM) and its innovation. Accordingly, it is argued that business model represents a mental model which underlines activities such as acquisition of market and technological insights, opportunities and requisite actions required for transforming a disruptive idea into a disruptive market movement. This view offers new insights into the study of disruptive phenomenon. It addresses the managerial (i.e. mental model) underpinnings of disruptiveness, instead of market, economical and technological dimensions. Business model innovation (BMI) is a disruptive change in the core logic of value creation and capture. It is a value-revolutionizing framework which explicitly delineates the strategic processes of a disruptive strategy. Thus, it is essentially a paradigm for strategizing the craft of disruptive innovation (technology). Given this view, this chapter conceptually explicates this contour and shows how BMI effectuates a disruptive technological phenomenon by presenting four propositions. Finally theoretical and managerial implications of this view are illuminated in order to furthering the practice and enhancing future research in this growing field of inquiry.
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Barros, Alistair. "Ubiquitous Services and Business Processes". En Ubiquitous and Pervasive Computing, 1688–719. IGI Global, 2010. http://dx.doi.org/10.4018/978-1-60566-960-1.ch104.
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In the commercial world, the value of ubiquitous computing applications is proportional to the range of business services that can be accessed in device-consumptive ways. Services originate in legacy applications of organizations, and are developed and operated typically in heterogeneous environments. Service-oriented architecture (SOA), supported by a complex stack of Web services standards, addresses ways in which software components of diverse applications can be homogeneously interacted with and composed. Thus, SOA provides a crucial mechanism for making services accessible to ubiquitous computing applications. In this chapter, we shed light on what SOA entails, based on Web services interfaces and messaging, and service composition through single-party process orchestration and multiparty choreography languages. For the latter, concrete patterns are used to describe the capabilities of prospective standards. Ways in which SOA needs be extended to allow wider and more flexible service trading, typified in current developments through service marketplaces, are then discussed. Such extensions, we argue, converge with directions in ubiquitous computing through so-called ubiquitous service networks and service ecosystems.
Actas de conferencias sobre el tema "Orchestration mechanisms"
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Iyer, Ganesh Neelakanta, Ramkumar Chandrasekaran y Bharadwaj Veeravalli. "Auction-based vs. incentive-based Multiple-Cloud orchestration mechanisms". En 2012 IEEE International Conference on Communication, Networks and Satellite (ComNetSat). IEEE, 2012. http://dx.doi.org/10.1109/comnetsat.2012.6380765.
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Beltre, Angel M., Pankaj Saha, Madhusudhan Govindaraju, Andrew Younge y Ryan E. Grant. "Enabling HPC Workloads on Cloud Infrastructure Using Kubernetes Container Orchestration Mechanisms". En 2019 IEEE/ACM International Workshop on Containers and New Orchestration Paradigms for Isolated Environments in HPC (CANOPIE-HPC). IEEE, 2019. http://dx.doi.org/10.1109/canopie-hpc49598.2019.00007.
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Arapoglou, Roi, Konstantinos Chatzikokolakis, George Katsikas y Nancy Alonistioti. "A dynamic governance framework for efficient orchestration of hetnet empowerment mechanisms". En 2013 International Conference on Smart Communications in Network Technologies (SaCoNeT). IEEE, 2013. http://dx.doi.org/10.1109/saconet.2013.6654593.
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Pelletier, Claudia, Dragos Vieru y Anne-Marie Croteau. "The Interorganizational Relationships Process: An Asset Orchestration Mechanisms Perspective in an SME Context". En Hawaii International Conference on System Sciences. Hawaii International Conference on System Sciences, 2017. http://dx.doi.org/10.24251/hicss.2017.668.
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Dominicini, Cristina Klippel, Magnos Martinello y Moisés Renato Nunes Ribeiro. "Programmable, Expressive, Scalable, and Agile Service Function Chaining for Edge Data Centers". En XXXVIII Simpósio Brasileiro de Redes de Computadores e Sistemas Distribuídos. Sociedade Brasileira de Computação, 2020. http://dx.doi.org/10.5753/sbrc_estendido.2020.12417.
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Edge computing transfers processing power from large remote data centers (DCs) to distributed DCs at the edge of the network. This shift requires the ability to provide network functions virtualization (NFV) solutions that can efficiently manage and combine a large number of dynamic services in a resource-constrained DC. However, the routing mechanisms of traditional data center networks are not adequate for the dynamic composition of these services, because they are complex, rigid, subject to large delays in the propagation of control information, and limited by the size of switches' routing tables. In addition, traditional service function chaining (SFC) solutions in the service overlay are often decoupled from routing decisions in the network underlay, and restrict path selection options by traffic engineering. In this way, the NFV orchestrator cannot explore the full capacity of the network to provide composite services. To tackle these issues, this thesis investigated a programmable, expressive, scalable, and agile SFC proposal that allows dynamic and efficient orchestration of the network infrastructure of edge DCs with commodity network equipment. The proposal exploits virtualization and programmability technologies of DC networks, server-centric DCs, fabric networks, and a source routing mechanism based on the residue number system (RNS). As proof-of-concept, we developed prototypes with production DC technologies, such as OpenFlow, OpenStack, Open vSwitch and P4. The results of functional and performance tests showed that the proposed SFC scheme provides mechanisms to the NFV orchestrator that allow traffic engineering to make optimized decisions in the selection of network paths. This thesis also paves the way for exploring RNS-based source routing properties in SFC schemes, which can provide features such as fast failure reaction and forwarding without packet rewrite. In a broader analysis, the student published 22 papers in journals and conferences, contributed to funding initiatives, worked on international and national research projects, supervised undergraduate students, and leaded initiatives with innovation impacts.
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Zhang, H., A. Laux, A. Flockton, D. Wang, C. J. Hu y K. R. Stenmark. "Orchestration of H3K27 Methylation Mechanisms of the Repression of MiR-124 and Therapeutic Implication in Pulmonary Hypertension". En American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7193.
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Chu Lijun, Zheng Xuefeng y Wang Shaojie. "2-layer orchestration mechanism for service composition". En 2008 3rd IEEE Conference on Industrial Electronics and Applications (ICIEA). IEEE, 2008. http://dx.doi.org/10.1109/iciea.2008.4582585.
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chu, lijun, Zheng Xuefeng y Wang Shaojie. "2-Layer Orchestration Mechanism for Service Composition". En 2nd International Conference on Bio-Inspired Models of Network, Information, and Computing Systems. Gent, BELGIUM: ICST, 2007. http://dx.doi.org/10.4108/icst.bionetics2007.2353.
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Mills, Ryan, Nicholas Race y Matthew Broadbent. "Citrus: Orchestrating Security Mechanisms via Adversarial Deception". En NOMS 2020-2020 IEEE/IFIP Network Operations and Management Symposium. IEEE, 2020. http://dx.doi.org/10.1109/noms47738.2020.9110443.
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Xie, Wuping, Jinyun Xue y Dongming Jiang. "Contract-Based Generic Programming Mechanism for Dynamic Service Orchestration". En 2014 IEEE International Conference on Computer and Information Technology (CIT). IEEE, 2014. http://dx.doi.org/10.1109/cit.2014.169.
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