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1

Rossmanith, Sara Edna Rowe, G. R. Wilt y Gin Wu. "Characterization and comparison of antimicrobial susceptibilities and outer membrane protein and plasmid DNA profiles of Pasteurella haemolytica and certain other members of the genus Pasteurella". American Journal of Veterinary Research 52, n.º 12 (1 de diciembre de 1991): 2016–22. http://dx.doi.org/10.2460/ajvr.1991.52.12.2016.

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SUMMARY The outer membrane protein (omp), plasmid, and antimicrobial resistance profiles of Pasteurella haemolytica serotypes 1 through 12, a bovine isolate of P multocida, a chicken isolate of P multocida, and an unidentified Pasteurella species of bovine origin were examined. Isolates of P haemolytica serotypes belonging to the same biotype possessed similar omp profiles. Biotype A isolates contained 2 prominent omp of 43 kilodaltons (kD) and 29 kD, whereas biotype-T serotypes contained 3 major omp of 43, 36, and 25 kD. The major omp profiles of the 2 P multocida isolates and the unidentified Pasteurella species were different from each other and from P haemolytica isolates. Plasmid dna screening indicated both plasmid-containing and plasmid-free P haemolytica and P multocida isolates. Multiple drug resistance was found in pasteurellae isolates with and without plasmids. However, a relationship between drug resistance and plasmid isolation was found in 3 of 4 P haemolytica serotype 1 field isolates, all of which contained a 2.51-megadalton plasmid and had multiple drug resistance for benzylpenicillin, ampicillin, streptomycin, and tetracycline.
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2

Mogilner, Leora y Cynthia Katz. "Pasteurella multocida". Pediatrics in Review 40, n.º 2 (febrero de 2019): 90–92. http://dx.doi.org/10.1542/pir.2017-0178.

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3

SHEFF, BARBARA. "Pasteurella multocida". Nursing 32, n.º 11 (noviembre de 2002): 72. http://dx.doi.org/10.1097/00152193-200211000-00050.

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4

Le Goff, C., D. Choudat y G. Paul. "Pasteurella multocida". Médecine et Maladies Infectieuses 18, n.º 5 (mayo de 1988): 297. http://dx.doi.org/10.1016/s0399-077x(88)80032-5.

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5

Sheff, Barbara. "Pasteurella multocida". Nursing (Ed. española) 21, n.º 5 (mayo de 2003): 52. http://dx.doi.org/10.1016/s0212-5382(03)71851-2.

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6

Seminа, A. N. "Identification of Pasteurella multocida by polymerase chain reaction". International bulletin of Veterinary Medicine 3 (2020): 14–18. http://dx.doi.org/10.17238/issn2072-2419.2020.3.14.

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Pasteurellosis having a fairly wide distri-bution can be a reason that hinders the suc-cessful development of poultry farming. The causes and conditions for the occurrence of this disease in farms are often not specific. Pasteurella multocida can manifest itself from an extremely weakened Pasteurella carrier to a highly virulent pathogen. A sick bird is a hidden carrier of this disease and is subject to further culling. All this ultimately leads to significant economic losses. Rapid and reliable detection of this patho-gen will reduce or completely prevent eco-nomic losses. The clinical manifestation of the disease in the form of a lightning course causes difficulties in its lifetime diagnosis. The aim of our work was to develop unique samples of oligonucleotide sequences of primers specific to the pathogen P. multo-cida. The proposed method will provide de-tection of Pasteurella multocida within 3-4 hours, as well as rapid and highly specific determination of the type of this bacterium. After analyzing the Pasteurella multo-cida genome, we selected a region of the ptfA gene for the construction of oligonu-cleotides. A pair of primers were selected for PCR: Pm0567 and Pm1321. Gene se-quences were aligned by selecting similar ones in absolutely all the studied Pasteurel-la multocida isolates. Using special com-puter programs, the specificity of the select-ed primers was evaluated. A search in the sequence database revealed 100% homolo-gy of the selected primers with only homol-ogous sequences in the Pasteurella multo-cida genome. The study of samples contain-ing pathologic agents of bacterial nature by PCR confirmed the specificity of the select-ed primers. Positive results were obtained only with samples containing Pasteurella multocida. Thus, the selected primers can be proposed for the study of samples of different compositions to identify the ge-nome of Pasteurella multocida.
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7

Hu, Xiao-hua, Ming Li, Lei Yang, Hui Chen, Zhong Chen, Wei-li Du y Yu-ming Shen. "Treatment of Pasteurella multocida infection with dressings containing honey and antibacterials: a case report". Journal of Wound Care 31, n.º 3 (2 de marzo de 2022): 230–34. http://dx.doi.org/10.12968/jowc.2022.31.3.230.

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Infections secondary to Pasteurella multocida frequently occur in patients who have been exposed to domestic pets. Human infections caused by Pasteurella multocida vary in severity, and clinical features include localised cellulitis, osteomyelitis, systemic bacteraemia, meningitis and pneumonia. No vaccine has been developed against Pasteurella multocida; it is treated with antibacterial agents and, in most cases, surgical intervention. This article discusses the authors' experience in treating a woman with severe cellulitis and osteomyelitis on her hand caused by Pasteurella multocida. She refused surgical intervention and was successfully treated with honey-containing dressings and antibiotics after failure to heal following conservative treatment using conventional wound dressings combined with antibiotics.
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8

Goldstein, Ellie J. C., Diane M. Citron y C. Vreni Merriam. "Linezolid Activity Compared to Those of Selected Macrolides and Other Agents against Aerobic and Anaerobic Pathogens Isolated from Soft Tissue Bite Infections in Humans". Antimicrobial Agents and Chemotherapy 43, n.º 6 (1 de junio de 1999): 1469–74. http://dx.doi.org/10.1128/aac.43.6.1469.

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ABSTRACT Linezolid was tested against 420 aerobes and anaerobes, including 148 Pasteurella isolates, by an agar dilution method. Linezolid was active against all Pasteurella multocidasubsp. multocida and P. multocida subsp.septica isolates and most Pasteurella canis,Pasteurella dagmatis, and Pasteurella stomatisisolates. The MIC was ≤2 μg/ml for staphylococci, streptococci, EF-4b, Weeksella zoohelcum, Fusobacterium nucleatum, other fusobacteria, Porphyromonas spp.,Prevotella spp., peptostreptococci, and almost allBacteroides tectum isolates.
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9

Moyko, Andrey, Nissa Ali, Nicole Dubosh y Matthew Wong. "Pasteurella multocida Epiglottitis". Clinical Practice and Cases in Emergency Medicine 1, n.º 1 (23 de febrero de 2017): 22–24. http://dx.doi.org/10.5811/cpcem.2016.11.32294.

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10

Al Soub, Hussam. "Pasteurella Multocida Empyema". Annals of Saudi Medicine 16, n.º 5 (septiembre de 1996): 591–93. http://dx.doi.org/10.5144/0256-4947.1996.591a.

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11

UMEBAYASHI, Yoshihiro, Michio OGASAWARA y Yoshibumi AKATSU. "Pasteurella Multocida Infections." Nishi Nihon Hifuka 61, n.º 1 (1999): 71–73. http://dx.doi.org/10.2336/nishinihonhifu.61.71.

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12

Poblete, Jose. "Pasteurella multocida Bacteremia". Infectious Diseases in Clinical Practice 17, n.º 2 (marzo de 2009): 77. http://dx.doi.org/10.1097/ipc.0b013e3181a02d62.

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13

Vondra, Mary S. y Joseph P. Myers. "Pasteurella multocida Bacteremia". Infectious Diseases in Clinical Practice 19, n.º 3 (mayo de 2011): 197–203. http://dx.doi.org/10.1097/ipc.0b013e31820994b8.

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14

Hombal, Shiril M. y Hosoon P. Dincsoy. "Pasteurella multocida Endocarditis". American Journal of Clinical Pathology 98, n.º 6 (1 de diciembre de 1992): 565–68. http://dx.doi.org/10.1093/ajcp/98.6.565.

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15

Hoffman, M. E., E. M. Sorr y M. Barza. "Pasteurella multocida endophthalmitis." British Journal of Ophthalmology 71, n.º 8 (1 de agosto de 1987): 609–10. http://dx.doi.org/10.1136/bjo.71.8.609.

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16

Tharmaseelan, K. y M. S. Morgan. "Pasteurella multocida conjunctivitis." British Journal of Ophthalmology 77, n.º 12 (1 de diciembre de 1993): 815. http://dx.doi.org/10.1136/bjo.77.12.815.

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17

Majid, Hashir y Prasad Manian. "PASTEURELLA MULTOCIDA EMPYEMA". Chest 134, n.º 4 (octubre de 2008): 64C. http://dx.doi.org/10.1378/chest.134.4_meetingabstracts.c64002.

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18

Mintz, Matthew L. y Gary L. Simon. "Pasteurella multocida Bacteremia". Infectious Diseases in Clinical Practice 6, n.º 2 (febrero de 1997): 118–21. http://dx.doi.org/10.1097/00019048-199702000-00011.

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19

Wine, N., Y. Lim y J. Fierer. "Pasteurella multocida Epiglottitis". Archives of Otolaryngology - Head and Neck Surgery 123, n.º 7 (1 de julio de 1997): 759–61. http://dx.doi.org/10.1001/archotol.1997.01900070103018.

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20

Hollick, Gary y Cynthia Christy. "Pasteurella multocida meningitis". Clinical Microbiology Newsletter 13, n.º 23 (diciembre de 1991): 181–83. http://dx.doi.org/10.1016/0196-4399(91)90010-s.

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21

Rebarber, Andrei, Jonathan Wright y Michael H. Cynamon. "Pasteurella multocida meningitis". Clinical Microbiology Newsletter 13, n.º 11 (junio de 1991): 85–87. http://dx.doi.org/10.1016/0196-4399(91)90039-x.

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22

Чжан Юй, Юй, Галина Ребенко, Цзяньхе Ху y Шоупінг Чжан. "Development of a Dual PCR Method for Detection of Pasteurella Multocida and Haemophilus Parasuis". Bulletin of Sumy National Agrarian University. The series: Veterinary Medicine, n.º 1 (52) (31 de marzo de 2021): 12–17. http://dx.doi.org/10.32845/bsnau.vet.2021.1.2.

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Pasteurella multocida and Haemophilus parasuis are the main pathogens of porcine respiratory disease syndrome, and often are the common pathogens of porcine pulmonary disease in collectivized pig farms. It has brought great influence on the pig industry and seriously hampered the healthy development of pigs. Therefore, the rapid detection method for Pasteurella multocida and Haemophilus parasuis is the key to its successful prevention and control. In the process of diagnosis, we need to conduct laboratory tests for confirming of preliminary diagnosis, that can be made based on the history, clinical symptoms, pathological changes of necropsy and epidemiological characteristics of the disease. Traditional diagnostic techniques, such as bacterial isolation and immunological test, are time-consuming and laborious, and are not suitable for rapid clinical diagnosis, nor for large-scale epidemiological investigation. Therefore, it is necessary to establish an accurate and rapid method to identify the two common respiratory pathogens in pigs. In this paper, Pasteurella multocida and Haemophilus parasuis were used as research objects to establish a dual PCR detection method. The main research contents are as follows: A dual PCR assay was established to detect Pasteurella multocida and Haemophilus parasuis simultaneously. By using Pasteurella multocida and Haemophilus parasuis specific primers, and adjusting primer concentration and annealing temperature, a dual PCR method for detecting Pasteurella multocida and Haemophilus parasuis was established. The rapid detection method for Pasteurella multocida and Haemophilus parasuis established in this study has high specificity and sensitivity, and can realize rapid and accurate identification of pathogenic bacteria in a relatively short period of time, providing a new technical means for rapid detection in clinical and grassroots laboratories
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23

Mobarak, S. S. A., A. K. Shubber y A. S. Raheem. "STUDY ON PATHOGENICITY OF PASTEURELLA MULTOCIDA WHICH ISOLATED FROM FARM ANIMALS AND MAN". Iraqi Journal of Veterinary Medicine 26, n.º 1 (30 de octubre de 2021): 74–81. http://dx.doi.org/10.30539/ijvm.v26i1.1122.

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This study was described for the nature of the pathpgenesis of bacteria Pasteurella multocida which was isolated from infected man made comparison between these bacteria and those from infected farm animals. The percentage of Pasteurella multcida diagnosed bacteria from animals and human was 29.4% and 16.9% respectively. Comparing to other culture media Pasteurella multocida selective agar medium was characterized by its selectivity and sensitivity and then was attempt for biotyping species and subspecies of isolated Pasteurella from animals and human samples were successfully achieved. Pathogenicity test was performed on mice, only nine human isolatetes and twenty-one animal isolates from Pasteurella multocida were virulent. Todistinguish between the pathogenesis of human and animal isolates, one isolated from human and animal were chosed, in addition to the standared strain. The mice had been experimentally infected by three different ways, I/P, I/T, I/Eye. The results were showed that Pasteurella multocida can produce lesions as fibrinous suppurative pneumonia in lungs, liver and spleen which were detected histopatho logically. However the animal isolates were more virulent than human or standared strain.
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24

demerdash, Ghada, Hossam Elsebaey, Sahar Mohamed y Amr Mahmoud. "Pasteurella multocida Infection in Duck, Detection of Virulence Genes and Antimicrobial Susceptibility of the Isolates". Alexandria Journal of Veterinary Sciences 76, n.º 1 (2023): 7. http://dx.doi.org/10.5455/ajvs.127124.

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Pasteurella multocida is a gram negative bacterium causing respiratory diseases in many birds including ducks resulting in great morbidity and mortality rates among them. Seventy five samples were collected from air sacs, lungs, livers, hearts and spleens were collected from different duck flocks which selected randomly and hade respiratory manifestations and diarrhea. All samples subjected to bacteriological examination for the presence of Pasteurella multocida (P. multocida). The results showed that Pasteurella multocida was isolated in a prevalence rate of as 13%. All isolates were identified by vitek 2 system. The virulence genes of two random isolates of Pasteurella multocida (toxA , tbpA and pfhA ) were detected by PCR. The results of antibiotic sensitivity test proved that the isolates were resistant to Cefalexin, Cefpodoxime, Ceftiofur, Amikacin, Nitrofurantoin, Trimethoprim, Rifampicin and Tetracycline. While the isolates were sensitive to Ampicillin, Amoxicillin/clavunic acid, Piperacillin, Cefpirome, Imipenen and Trimethoprim/Sulfamethoxazle. The three examined virulence genes were detected in both samples.
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25

Saif, Kazi Md, Ferdousi Begum, Saifur Rahman, Md Shafiqul Islam, KHM Nazmul Hussain Nazir y Md Shahidur Rahman Khan. "Molecular identification and antibiogram profiles of respiratory bacterial agents isolated from cattle reared in some selected areas of Mymensingh division, Bangladesh". Asian-Australasian Journal of Bioscience and Biotechnology 4, n.º 1 (30 de abril de 2019): 60–66. http://dx.doi.org/10.3329/aajbb.v4i1.64949.

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Respiratory bacterial infections in cattle are very common all over Bangladesh causing high economic loss. This research was performed with a view to proper control of respiratory bacterial infections of cattle in Bangladesh. A total of 100 nasal samples were collected on the basis of clinical signs. From the collected samples isolation, identification and characterization of the bacterial agents was done using cultural, biochemical and molecular techniques. Antibiogram profiles of the isolated agents were studied by disc diffusion method. Pasteurella multocida, Staphylococcus aureus and Escherichia coli were successfully isolated and identified from the collected samples. The isolated Pasteurella multocida produced small, round, opaque colonies on blood agar; Staphylococcus aureus produced golden yellow colony in mannitol salt agar; E. coli produced black color colonies with metallic sheen on EMB agar. Pasteurella multocida showed Gram negative, bipolar rods. Staphylococcus aureus showed Gram positive, cocci shaped and E. coli showed Gram negative, small rod shaped. Among 100 nasal samples 16 were found to be positive for Pasteurella multocida, 21 for Staphylococcus aureus and 13 for E. coli on the basis of cultural and biochemical characteristics. The antibiogram study reflected that ciprofloxacin, tetracycline and chloramphenicol should be first choice of treatment of respiratory bacterial infections caused by the isolated 3 bacteria. Pasteurella multocida was further characterized by PCR where 16 isolates showed positive band at 460 bp and Pasteurella multocida type A at 1044 bp. The present research work covering antibiogram study is a preliminary report in the context of Bangladesh. Asian Australas. J. Biosci. Biotechnol. 2019, 4 (1), 60-66
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26

Raj, Rajneesh, Ashwani Kumar Sharma y Anil Kumar Arora. "Pasteurella multocida effectively utilizes hyaluronic acid to facilitate its continuous growth - short comminication". Veterinarski arhiv 93, n.º 5 (25 de octubre de 2023): 549–58. http://dx.doi.org/10.24099/vet.arhiv.1837.

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Pasteurella multocida B: 2 (P. multocida) causes haemorrhagic septicemia (HS), a fatal disease in cattle and buffalo. Despite its widespread prevalence, little is known about the factors that contribute to P. multocida’s pathogenicity. This pathogen produces hyaluronidase, a hyaluronic acid degrading enzyme. However, its role in P. multocida pathogenicity is unknown. In this study we attempted to assess the potential of P. multocida in utilising hyaluronic acid as a nutrient in vitro. Six isolates of P. multocida, isolated from outbreaks of HS, were examined for their growth in a chemically defined medium (CDM) with glucose, and a CDM without glucose but with hyaluronic acid (HA) added. The bacterial growth was determined by counting the number of colonies at each observation time (24, 48, 72, 96 h), and was expressed as CFU millions/mL log10. P. multocida continued to grow throughout the period of the experiment in the CDM with HA. However, in the CDM with glucose, growth could be observed until 72 h, followed by a decline and then no growth after that. This is the first ever report of P. multocida utilising hyaluronic acid for its growth, a strategy that could be used to obtain nutrients for colonisation and proliferation.
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27

Ferguson, KB, R. Bharadwaj, A. MacDonald, B. Syme y AM Bal. "Pasteurella multocida infected total knee arthroplasty: a case report and review of the literature". Annals of The Royal College of Surgeons of England 96, n.º 2 (marzo de 2014): e1-e4. http://dx.doi.org/10.1308/003588414x13814021676710.

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Pasteurella multocida is a rare cause of prosthetic joint infection. This infection generally follows significant animal contact, usually licks and scratches. We report a case of P multocida infection that was treated with linezolid with salvage of the implant. Linezolid is generally active against Gram-positive organisms only with the exception of Pasteurella, which is Gram-negative. We extensively review the previous reported cases of implant infection with P multocida.
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28

Olm, Marta, E. Kanterewich, J. Hach y J. Rodes. "Pasteurella multocida vertebral osteomyelitis". Medical Journal of Australia 148, n.º 6 (marzo de 1988): 318. http://dx.doi.org/10.5694/j.1326-5377.1988.tb117849.x.

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29

Bourée, P. "Péritonite à Pasteurella multocida". Médecine et Santé Tropicales 26, n.º 1 (enero de 2016): 20. http://dx.doi.org/10.1684/mst.2016.0560.

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30

Bourée, P. "Péritonite à Pasteurella multocida". Médecine et Santé Tropicales 26, n.º 3 (julio de 2016): 238. http://dx.doi.org/10.1684/mst.2016.0585.

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31

ROBERTS, SHAUNA R., JOHN W. ESTHER y JOSEPH H. BREWER. "Posttraumatic Pasteurella multocida Meningitis". Southern Medical Journal 81, n.º 5 (mayo de 1988): 675–76. http://dx.doi.org/10.1097/00007611-198805000-00036.

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32

RAFFI, FRANCOIS, ALBERT DAVID, ALAIN MOUZARD, JEAN CLAUDE LE NEEL, DENIS BARON y ANDRÉ LOUIS COURTIEU. "Pasteurella multocida appendiceal peritonitis". Pediatric Infectious Disease Journal 5, n.º 6 (noviembre de 1986): 695–98. http://dx.doi.org/10.1097/00006454-198611000-00019.

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33

De los Santos, S., A. Gonzalez, F. Capote, J. Lopez Mejias y P. Fernandez. "Neumonia por pasteurella multocida". Archivos de Bronconeumología 23, n.º 1 (enero de 1987): 35–36. http://dx.doi.org/10.1016/s0300-2896(15)31995-5.

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P.D. "Septicemies A Pasteurella Multocida". Médecine et Maladies Infectieuses 18, n.º 2 (febrero de 1988): 151. http://dx.doi.org/10.1016/s0399-077x(88)80221-x.

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35

Collins, Timothy P., Carla Lamb y Donald Craven. "PASTEURELLA MULTOCIDA EMPYEMA NECESSITANS". Chest 132, n.º 4 (octubre de 2007): 708A. http://dx.doi.org/10.1378/chest.132.4_meetingabstracts.708.

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36

Nauseef, Jones T., Nathan B. Price y Kelly E. Wood. "Infantile Pasteurella multocida meningitis". IDCases 6 (2016): 31–33. http://dx.doi.org/10.1016/j.idcr.2016.09.009.

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37

Young, Pablo. "Endocarditis por Pasteurella multocida". Fronteras en Medicina 17, n.º 2 (1 de junio de 2022): 0133–35. http://dx.doi.org/10.31954/rfem/202202/0133-0135.

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38

Tabatabai, Louisa B. y Emilie S. Zehr. "Identification of Five Outer Membrane-Associated Proteins among Cross-Protective Factor Proteins of Pasteurella multocida". Infection and Immunity 72, n.º 2 (febrero de 2004): 1195–98. http://dx.doi.org/10.1128/iai.72.2.1195-1198.2004.

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ABSTRACT Fowl cholera is caused by Pasteurella multocida serovars A:1, A:3, and A:4. The 39-kDa cross-protective factor protein and four other membrane proteins of the membrane proteome of P. multocida were identified. We determined that the 39-kDa cross-protective protein was Pasteurella lipoprotein B, or PlpB.
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39

Dammeijer, P. F. y A. W. McCombe. "Meningitis from canine Pasteurella multocida following mastoidectomy". Journal of Laryngology & Otology 105, n.º 7 (julio de 1991): 571–72. http://dx.doi.org/10.1017/s0022215100116639.

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AbstractA case of Pasteurella multocida meningitis, following a mastoidectomy is presented. The association of close contact with pets, many of which harbour Pasteurella multocida as part of their normal buccal flora. This case confirms the potential benefit of taking an ear swab prior to mastoid surgery and in seeking an appropriate ‘pet’ history.
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40

Morés, Marcos A. Z., João X. Oliveira Filho, Raquel Rebelatto, Cátia S. Klein, David E. N. Barcellos, Arlei Coldebella y Nelson Morés. "Aspectos patológicos e microbiológicos das doenças respiratórias em suínos de terminação no Brasil". Pesquisa Veterinária Brasileira 35, n.º 8 (agosto de 2015): 725–33. http://dx.doi.org/10.1590/s0100-736x2015000800004.

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Resumo: Para avaliação dos aspectos patológicos e microbiológicos de casos clínicos de doenças respiratórias em suínos de terminação foram analisados 75 suínos doentes oriundos de 36 lotes. Suínos que apresentavam sinais clínicos respiratórios evidentes foram necropsiados para avaliação macroscópica e colheita de amostras para análise histopatológica e microbiológica. Foram realizados testes de isolamento bacteriano para as principais bactérias do sistema respiratório dos suínos, PCR para Mycoplasma hyorhinis, imuno-histoquímica para Influenza A, Circovirus suíno tipo 2 e Mycoplasma hyopneumoniae. A sensibilidade antimicrobiana de 24 amostras de Pasteurella multocida tipo A foi avaliada por testes de concentração inibitória mínima para os principais antimicrobianos utilizados em suinocultura. Mycoplasma hyopneumoniae e Pasteurella multocida tipo A foram os agentes infecciosos mais prevalentes. Broncopneumonia supurativa e pleurite foram as principais lesões respiratórias encontradas. Pasteurella multocida tipo A, quando presente, aumentou a extensão das lesões pulmonares. Todas as amostras de Pasteurella multocida testadas foram sensíveis aos antimicrobianos Doxiciclina, Enrofloxacina e Tilmicosina. Em 58% das amostras foi identificado mais de um agente infeccioso, evidenciando a alta prevalência da associação de agentes nas doenças respiratórias de suínos em terminação.
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41

Cabras, Ornella, Jean-Marie Turmel, Claude Olive, Bastien Bigeard, Mélanie Lehoux, Sandrine Pierre-Francois, Karine Guitteaud, Sylvie Abel, Lise Cuzin y André Cabié. "COVID-19 and Pasteurella multocida Pulmonary Coinfection: A Case Series". Tropical Medicine and Infectious Disease 7, n.º 12 (11 de diciembre de 2022): 429. http://dx.doi.org/10.3390/tropicalmed7120429.

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Objectives: In COVID-19 patients, bacterial and fungal pulmonary coinfections, such as Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, or Aspergillus, have been reported, but to our knowledge, no case has been reported due to Pasteurella multocida. Patients and methods: We describe three cases of Pasteurella multocida coinfections occurring during the 4th wave of COVID-19 in Martinique (French West Indies). Results: All three cases were fatal; thus, Pasteurella multocida has to be considered as a potentially severe coinfection agent. Conclusions: Alteration of the epithelial–endothelial barrier due to a SARS-CoV-2 infection probably promotes the expression of a Pasteurella infection. In addition, the SARS-CoV-2 infection induced immunosuppression, and an inflammatory cascade could explain the infection’s severity. The use of corticosteroids, which are part of the first-line therapeutic arsenal against COVID-19, may also promote the pathogenicity of this agent.
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42

Akondi, Sivaramakrishna, Anil Kumar Arora y Narinder Singh Sharma. "Development and application of a loop-mediated isothermal amplification method for rapid detection of Pasteurella multocida". Buffalo Bulletin 41, n.º 2 (26 de junio de 2022): 318. http://dx.doi.org/10.56825/bufbu.2022.4123763.

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Pasteurella multocida is an important pathogen affecting livestock and poultry causing significant economic losses. A loop-mediated isothermal amplification (LAMP) assay using four primers targeting a conserved region of the kmt1 gene was standardised to diagnose Pasteurella multocida. The test was carried out at 64oC for 45 minutes, the LAMP products could be visually confirmed using fluorescent dye SYBR Green I as detection reagent both with naked eye as well as under UV-illumination. The sensitivity of the developed LAMP assay was 104 fold higher than PCR. Furthermore, no cross-reactivity was found with the other tested bacteria. The developed LAMP assay allows easy, rapid, accurate and sensitive detection of Pasteurella multocida.
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43

Akter, Taslima, Md Shahidur Rahman Khan, Saifur Rahman, Md Ariful Islam y Md Shafiqul Islam. "Isolation and molecular detection of respiratory bacterial agents from buffalo reared in some selected areas of Bangladesh". Asian Journal of Medical and Biological Research 4, n.º 4 (30 de diciembre de 2018): 416–21. http://dx.doi.org/10.3329/ajmbr.v4i4.40115.

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In buffalo respiratory bacterial infection is very common which occurs sporadically or enzootically all over Bangladesh causing high economic loss. The study was performed with a view to proper control of respiratory bacterial infection in Buffalo. A total of 40 samples were collected on the basis of clinical signs. The samples were then subjected to isolation, identification and characterization of the bacterial agents using cultural, biochemical and molecular techniques. Antibiogram profiles of the isolated agents were studied by disc diffusion method. Pasteurella multocida, Staphylococcus aureus and E. coli were successfully isolated and identified from the collected samples. The isolated Pasteurella multocida produced small, round, opaque colonies on blood agar; Staphylococcus aureus produced golden yellow colony in mannitol salt agar; E. coli produced black color colonies with metallic sheen on EMB agar. Pasteurella multocida showed Gram negative, bipolar rods. Staphylococcus aureus showed Gram positive, cocci shaped and E. coli showed Gram negative, small rod shaped. On the basis of cultural and biochemical characteristics, among 40 nasal samples 5 were found to be positive for Pasteurella multocida, 4 for Staphylococcus aureus and 3 for E. coli. Pasteurella multocida was further confirmed by PCR where isolates showed positive band at 620 bp. The antibiogram study concluded that amoxicillin, gentamicin, & ciprofloxacin should be the first choice of treatment for respiratory bacterial infection caused by the isolated 3 bacteria. Asian J. Med. Biol. Res. December 2018, 4(4): 416-421
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44

Dabo, S. M., J. D. Taylor y A. W. Confer. "Pasteurella multocidaand bovine respiratory disease". Animal Health Research Reviews 8, n.º 2 (diciembre de 2007): 129–50. http://dx.doi.org/10.1017/s1466252307001399.

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AbstractPasteurella multocidais a pathogenic Gram-negative bacterium that has been classified into three subspecies, five capsular serogroups and 16 serotypes.P. multocidaserogroup A isolates are bovine nasopharyngeal commensals, bovine pathogens and common isolates from bovine respiratory disease (BRD), both enzootic calf pneumonia of young dairy calves and shipping fever of weaned, stressed beef cattle.P. multocidaA:3 is the most common serotype isolated from BRD, and these isolates have limited heterogeneity based on outer membrane protein (OMP) profiles and ribotyping. Development ofP. multocida-induced pneumonia is associated with environmental and stress factors such as shipping, co-mingling, and overcrowding as well as concurrent or predisposing viral or bacterial infections. Lung lesions consist of an acute to subacute bronchopneumonia that may or may not have an associated pleuritis. Numerous virulence or potential virulence factors have been described for bovine respiratory isolates including adherence and colonization factors, iron-regulated and acquisition proteins, extracellular enzymes such as neuraminidase, lipopolysaccharide, polysaccharide capsule and a variety of OMPs. Immunity of cattle against respiratory pasteurellosis is poorly understood; however, high serum antibodies to OMPs appear to be important for enhancing resistance to the bacterium. Currently availableP. multocidavaccines for use in cattle are predominately traditional bacterins and a live streptomycin-dependent mutant. The field efficacy of these vaccines is not well documented in the literature.
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45

Peng, Zhong, Wan Liang, Wenjing Liu, Huanchun Chen y Bin Wu. "Genome characterization of Pasteurella multocida subspecies septica and comparison with Pasteurella multocida subspecies multocida and gallicida". Archives of Microbiology 199, n.º 4 (7 de febrero de 2017): 635–40. http://dx.doi.org/10.1007/s00203-017-1341-x.

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46

Elsayed, Mossad, Ashraf Elkomy y Faten Ibrahim. "Pharmacokinetics of thiamphenicol in normal and pasteurella multocida infected lactating goats". International Journal of Pharmacology and Toxicology 5, n.º 2 (4 de junio de 2017): 61. http://dx.doi.org/10.14419/ijpt.v5i2.7598.

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The pharmacokinetic parameters of thiamphenicol following intravenous and intramuscular (single & repeated) administrations were estimated in normal and experimentally pasteurella multocida infected goats. Following a single intravenous injection of 30 mg thiamphenicol /kg b.wt. in normal goats, thiamphenicol could be detected therapeutically for 24 hours post intravenous injection. The serum concentration – time curve of thiamphenicol following intravenous injection showed that the drug obeyed a two compartments open model. The intramuscular bioavailability of thiamphenicol in normal goats was 66.63 %. Intramuscular injection of 30 mg thiamphenicol per kilogram body weight once daily for five consecutive days in normal and pastreulla multocida infected goats revealed a lower significant serum thiamphenicol concentration in pastreulla multocida infected goats compared with normal goats, also it’s found that: marked significant decrease in ( k1, K12, K21, T0.5(α) , T0.5(β), Tmax and CLtot in normal compared with infected goats, on the other hand a significant increase in Cmax,AUC, C0,B and β in normal compared with infected goats. Thiamphenicol was cleared by all clearance processes (Cltot) in the body at significant faster rates in Pasteurella multocida infected goats than in normal goats. The concentrations of thiamphenicol in milk were significantly lower in Pasteurella multocida infected goats than in normal goats. The mean peak urine concentrations of thiamphenicol were reached 4 hours after each intramuscular dose with a lower significant concentration in Pasteurella multocida infected goats than in normal goats.
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47

Буйенбаева, Зарина, Z. Latypova, B. Issakulova, A. Namet, А. Makbuz y U. Seytzhanova. "Биологические свойства циркулирующих штаммов Pasteurella multocida на территории Республики Казахстан". Ġylym ža̋ne bìlìm 1, n.º 1 (70) (28 de marzo de 2023): 59–65. http://dx.doi.org/10.52578/2305-9397-2023-1-1-59-65.

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The article presents the results of studies on the study of cultural, tinctorial, biochemical and virulence properties of Pasteurella multocida strains isolated from cattle. In order to refresh the isolated strains and increase their virulent properties, successive passages were carried out through the body of white mice. According to the results of the bioassays, a reduction in the period of death of mice after infection with Pasteurella cultures was established, which proves an increase in their virulence. When studying the cultural and morphological properties, pure cultures of Pasteurella were grown on nutrient media at 37°C for 18–24 h. A biochemical test on Hiss medium was used to fully confirm the data obtained. The test cultures isolated from pathological material (heart, lung, spleen, liver, intestines ) of cattle have cultural, biochemical and biological properties characteristic of the Pasteurella multocida species and form S-shaped colonies. Isolated cultures of Pasteurella multocida can be used to evaluate the immunogenicity of existing vaccines and use them as a basis for the development of anti-pasteurellosis polyvalent emulsion vaccines, anti-pasteurellosis hyperimmune serum and e.t.c.
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48

Piorunek, Marcin, Beata Brajer-Luftmann y Jarosław Walkowiak. "Pasteurella Multocida Infection in Humans". Pathogens 12, n.º 10 (1 de octubre de 2023): 1210. http://dx.doi.org/10.3390/pathogens12101210.

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Pasteurella multocida (P. multocida) is an immobile, anaerobic, Gram-negative coccobacillus fermenting bacterium. This pathogen is commonly prevalent in the upper airways of healthy pets, such as cats and dogs, but was also confirmed in domestic cattle, rabbits, pigs, birds, and various wild animals. Infection in humans occurs as a result of biting, scratching, or licking by animals and contact with nasopharyngeal secretions. Inflammation at the site of infection develops within the first day from the injury. It is usually confined to the skin and subcutaneous tissue but, in particular situations, may spread to other organs and manifest as a severe systemic infection. Careful history-taking and microbiological confirmation of the infection enable diagnosis and appropriate treatment. Any wound resulting from an animal bite should be disinfected. The preferred and highly effective treatment against local P. multocida infection is penicillin or its derivatives. The prognosis for P. multocida infections depends on the infected site and the patient’s comorbidities.
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49

Galecio, Juan Sebastián, Elena Badillo, Elisa Escudero, Juan Carlos Corrales, María Teresa Yuste y Pedro Marín. "Antimicrobial Susceptibility of Pasteurella multocida Isolated from Sheep with Fibrinous Pneumonia". Acta Veterinaria 73, n.º 2 (1 de junio de 2023): 171–78. http://dx.doi.org/10.2478/acve-2023-0013.

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Abstract Ovine respiratory complex is a significant cause of death in sheep flocks, where Pasteurella multocida is the most frequent microorganisms isolated from animals with pneumonia. There is an urgent need to refine the use of different antimicrobials to avoid the problem of antimicrobial resistance and optimize the control of this disease in ovine livestock. The first step in approaching this problem is gaining an insight into the antimicrobial susceptibility of ovine pathogens. This study evaluated the in vitro activity of tildipirosin, gamithromycin, oxytetracycline, and danofloxacin against Pasteurella multocida strains isolated from sheep with fibrinous pneumonia. The strains were incubated following Clinical and Laboratory Standards Institute (CLSI) standard conditions and also with a modified method by 25% supplementation with sheep serum. Minimum inhibitory concentrations (MIC) were determined using the broth microdilution technique. The lowest MIC90 under standard conditions and by supplementation with sheep serum was obtained with tildipirosin. Sheep serum significantly reduced tildipirosin, gamithromycin, and danofloxacin MIC values for Pasteurella multocida strains. In brief, the potency of tildipirosine, gamithromycin, and danofloxacin against Pasteurella multocida increases when sheep serum is added to the culture media.
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50

Christensen, Henrik, Øystein Angen, John Elmerdahl Olsen y Magne Bisgaard. "Revised description and classification of atypical isolates of Pasteurella multocida from bovine lungs based on genotypic characterization to include variants previously classified as biovar 2 of Pasteurella canis and Pasteurella avium". Microbiology 150, n.º 6 (1 de junio de 2004): 1757–67. http://dx.doi.org/10.1099/mic.0.26720-0.

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Strains deviating in key phenotypic characters, mainly isolated from cases of bovine pneumonia in five European countries, were genotyped in order to examine their genotypic relationship with Pasteurella multocida. Twenty-two strains of Pasteurella avium biovar 2, including variants in indole, xylose and mannitol, 18 strains of Pasteurella canis biovar 2 and variants of this taxon, five strains of P. multocida subsp. septica showing variations in indole and ornithine decarboxylase, nine strains of P. multocida subsp. multocida showing variation in ornithine decarboxylase and mannitol, and type strains of the subspecies of P. multocida were included. Ribotyping was used to examine the relationship of the strains, and 13 types, each containing between one and 20 isolates, were observed. Identical ribotypes were observed in some cases for P. avium biovar 2 and either P. canis biovar 2 or P. multocida subsp. septica. ITS (16S–23S rRNA internal transcribed spacer) fragment-length profiling showed identity of the majority of strains (47 of 52), representing all four taxa, with only five divergent strains. A 16S rRNA sequence comparison of 11 strains representing the main ribotype clusters showed 99·9 % similarity to the type strain of P. multocida subsp. multocida, but only 97·4 % similarity was obtained to P. canis (biovar 1) and 93·7 % to P. avium (biovar 1). A species-specific PCR test for P. multocida gave a positive result with biovar 2 variants of P. avium and P. canis. DNA–DNA hybridizations between strains of P. multocida, biovar 2 variants of P. avium and P. canis, and P. multocida subsp. septica confirmed similarity at the species level. It is proposed, on the basis of genotypic similarity, that P. multocida be reclassified to include the biovar 2 variants of P. avium and P. canis and that the existence of the biovar 2 variants of P. avium and P. canis is highly questionable. It is concluded that the redefined P. multocida is genotypically homogeneous, although phenotypically diverse lineages exist with respect to ornithine decarboxylase, indole and mannitol, characters that have been regarded as essential for identification to the species level. A formal reclassification of the species is not possible, however, since too few strains have been found to vary in these key characters. Considering the phenotypic diversity of P. multocida, identification will have to depend partly on genotypic methods and the source host also seems important for safe diagnosis.
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