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1

Pantelyat, Alexander, Lenora Higginbotham, Liana Rosenthal, Diane Lanham, Vanessa Nesspor, Mina AlSalihi, Jee Bang, Jiangxia Wang y Marilyn Albert. "Association of Progressive Supranuclear Palsy Rating Scale with Progressive Supranuclear Palsy Quality of Life Scale". Neurodegenerative Diseases 20, n.º 4 (2020): 139–46. http://dx.doi.org/10.1159/000514519.

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<b><i>Introduction:</i></b> There is growing interest in using patient-reported outcomes as end points in clinical trials, such as the progressive supranuclear palsy quality of life (PSP-QoL) scale. However, this tool has not been widely validated and its correlation with validated motor scales has not been explored. To evaluate the potential utility of using PSP-QoL as an outcome, it is important to examine its relationship with a standard scale used to evaluate neurologic parameters, such as the PSP Rating Scale. <b><i>Methods:</i></b> PSP-QoL and PSP Rating Scale scores were gathered from 60 clinically diagnosed PSP patients, including patients with Richardson syndrome PSP (PSP-RS, <i>n</i> = 43) and those with non-RS PSP variants (<i>n</i> = 17). Linear regression analysis adjusted for age, sex, and disease duration was used to evaluate the cross-sectional relationship between the total and subscale scores of the 2 instruments. <b><i>Results:</i></b> Among 60 PSP patients, there was a significant correlation between total PSP-QoL and PSP Rating Scale scores. The physical and mentation subscales of each instrument also demonstrated significant correlations. Comparisons among PSP subtypes indicated that worsening PSP-QoL Total and Physical subscale scores correlated with worsening PSP Rating Scale gait subscale scores more strongly for the non-RS PSP variants than for PSP-RS. <b><i>Discussion:</i></b> There is a significant association between the total scores and many of the subscale scores of the PSP-QoL and the PSP Rating Scale. Additionally, the relationship between these measures may differ for PSP-RS and non-RS variants. These findings suggest that the PSP-QoL may be useful in clinical trials as a patient-reported outcome measure. Large prospective multicenter studies utilizing the PSP-QoL are necessary to examine its relationship to disease evolution and changes in the PSP Rating Scale.
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2

Agosta, Federica, Francesca Caso, Milica Ječmenica-Lukić, Igor N. Petrović, Paola Valsasina, Alessandro Meani, Massimiliano Copetti, Vladimir S. Kostić y Massimo Filippi. "Tracking brain damage in progressive supranuclear palsy: a longitudinal MRI study". Journal of Neurology, Neurosurgery & Psychiatry 89, n.º 7 (18 de enero de 2018): 696–701. http://dx.doi.org/10.1136/jnnp-2017-317443.

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ObjectivesIn this prospective, longitudinal, multiparametric MRI study, we investigated clinical as well as brain grey matter and white matter (WM) regional changes in patients with progressive supranuclear palsy-Richardson’s syndrome (PSP-RS).MethodsTwenty-one patients with PSP-RS were evaluated at baseline relative to 36 healthy controls and after a mean follow-up of 1.4 years with clinical rating scales, neuropsychological tests and MRI scans.ResultsRelative to controls, patients with PSP-RS showed at baseline a typical pattern of brain damage, including midbrain atrophy, frontal cortical thinning and widespread WM involvement of the main infratentorial and supratentorial tracts that exceeded cortical damage. Longitudinal study showed that PSP-RS exhibited no further changes in cortical thinning, which remained relatively focal, while midbrain atrophy and WM damage significantly progressed. Corpus callosum and frontal WM tract changes correlated with the progression of both disease severity and behavioural dysfunction.ConclusionsThis study demonstrated the feasibility of carrying out longitudinal diffusion tensor MRI in patients with PSP-RS and its sensitivity to identifying the progression of pathology. Longitudinal midbrain volume loss and WM changes are associated with PSP disease course.
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Picillo, Marina, Maria Francesca Tepedino, Filomena Abate, Roberto Erro, Sara Ponticorvo, Salvatore Tartaglione, Giampiero Volpe et al. "Midbrain MRI assessments in progressive supranuclear palsy subtypes". Journal of Neurology, Neurosurgery & Psychiatry 91, n.º 1 (16 de septiembre de 2019): 98–103. http://dx.doi.org/10.1136/jnnp-2019-321354.

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ObjectivesTo explore the role of the available midbrain-based MRI morphometric assessments in (1) differentiating among progressive supranuclear palsy (PSP) subtypes (PSP Richardson’s syndrome (PSP-RS), PSP with predominant parkinsonism (PSP-P) and the other variant syndromes of PSP (vPSP)), and (2) supporting the diagnosis of PSP subtypes compared with Parkinson’s disease (PD) and healthy controls (HC).MethodsSeventy-eight patients with PSP (38 PSP-RS, 21 PSP-P and 19 vPSP), 35 PD and 38 HC were included in the present analysis. Available midbrain-based MRI morphometric assessments were calculated for all participants.ResultsCurrent MRI midbrain-based assessments do not display an adequate sensitivity and specificity profile in differentiating PSP subtypes. On the other hand, we confirmed MR Parkinsonism Index (MRPI) and pons area to midbrain area ratio (P/M) have adequate diagnostic value to support PSP-RS clinical diagnosis compared with both PD and HC, but low sensitivity and specificity profile in differentiating PSP-P from PD as well as from HC. The same measures show acceptable sensitivity and specificity profile in supporting clinical diagnosis of vPSP versus HC but not versus PD. Similar findings were detected for the newer MRPI and P/M versions.ConclusionsFurther studies are warranted to identify neuroimaging biomarkers supporting the clinical phenotypic categorisation of patients with PSP. MRPI and P/M have diagnostic value in supporting the clinical diagnosis of PSP-RS.Classification of evidenceThis study provides class III evidence that available MRI midbrain-based assessments do not have diagnostic value in differentiating the Movement Disorder Society PSP subtypes.
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Addelia, Gita Nevara, Shyan Yea Chay, Kharidah Muhammad, Hasanah Mohd Ghazali y Roselina Karim. "How Pullulanase Affects Resistant Starch and Antioxidant Activity in Purple Sweet Potato Powder?" Turkish Journal of Agriculture - Food Science and Technology 7, n.º 11 (22 de noviembre de 2019): 1795. http://dx.doi.org/10.24925/turjaf.v7i11.1795-1798.2621.

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Purple sweet potato (PSP) serves as a potential source for dual functionalities of resistant starch (RS) and antioxidants. This study aims to evaluate the effects of pullulanase enzyme on these functionalities. Results showed that the incorporation of pullulanase into PSP powder could significantly increase the RS content from 3.06 g/100g to 7.11 g/100g. However, total anthocyanin content and DPPH radical scavenging activity reduced significantly, due to the interference from RS fragments on anthocyanins. Securing both functionalities (RS and antioxidant) within the same sample is seemingly impossible. A compromise between RS and antioxidant properties in coloured, starchy plant powders is recommended.
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Ariyarathne, H. M. y D. P. Coyne. "Inheritance of Resistance to Halo Blight Flower and Stem Color and Association in Common Beans". HortScience 31, n.º 4 (agosto de 1996): 621d—621. http://dx.doi.org/10.21273/hortsci.31.4.621d.

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Halo blight is one of the most important bacterial diseases of common beans (Phaseolus vulgaris L.). It is serious under moderate temperature and high humidity conditions. The disease is caused by a seed-borne bacterium, Pseudomonas syringae pv. phaseolicola (Burkh.) Dowson (Psp). The inheritance of leaf reactions to Psp, flower, and stem color was studied using greenhouse-grown 109 F9 recombinant inbred lines (RI) from the P. vulgaris cross BelNeb 1 [resistant (R)] (USDA/NE) × A 55 [susceptible (S)] (CIAT). Two Psp strains, HB16 (NE) and 83-Sc2A (NE), were inoculated using the water-soaking method. A segregation ratio of 1 R:1 S RI lines were observed for disease reactions in leaves for both strains indicating major gene control. The presence of recombinants for SR, RS to the strains indicated that different genes were involved. Stem (SC) and flower (FC) color traits were each determined by two major genes. Linkages were found for reactions to the two Psp strains and also between FC and SC. No linkages were observed from FC and also SC with reactions to Psp strains.
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Taziwa, R., E. Meyer, D. Katwire y L. Ntozakhe. "Influence of Carbon Modification on the Morphological, Structural, and Optical Properties of Zinc Oxide Nanoparticles Synthesized by Pneumatic Spray Pyrolysis Technique". Journal of Nanomaterials 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/9095301.

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This paper reveals the influence of doping on the morphological, structural, and optical properties of zinc oxide (ZnO) nanoparticles (NPs) synthesized by pneumatic spray pyrolysis technique (PSP), using zinc ethoxide ZnO2CH32 as the precursor. The prepared samples were characterized by XRD, HRTEM, SEM-EDX, UV-Vis spectroscopy, and RS. RS analysis has revealed that the unmodified ZnO and carbon modified ZnO samples have characteristic Raman optic modes at 325 cm−1, 373 cm−1, and 432 cm−1 belonging to Wurtzite ZnO structure. The XRD ZnO (C:ZnO) NPS have characteristic peaks of hexagonal Wurtzite ZnO structure. HRTEM analysis has revealed that the synthesized ZnO NPs have particle size range of 8.8–11.82 nm. EDX spectra of both unmodified and modified ZnO nanoparticles have revealed prominent peaks at 0.51 keV, 1.01 keV, 1.49 keV, 8.87 keV, and 9.86 keV. The occurrence of these peaks in the EDX spectra endorses the existence of Zn and O atoms in the PSP synthesized ZnO NPs. The UV-Vis spectroscopy has revealed a red shift of the absorption edge, with the increase in C dopant level. The effect of nanocrystallite size and the gradual prominence of C into ZnO matrix due to increase in C dopant level in the PSP synthesized ZnO NPs was meticulously elaborated through Raman spectroscopy analysis.
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7

Balestrieri, M., M. Isola, R. Bonn, T. Tam, A. Vio, M. Linden y E. Maso. "Validation of the Italian version of Mini-ICF-APP, a short instrument for rating activity and participation restrictions in psychiatric disorders". Epidemiology and Psychiatric Sciences 22, n.º 1 (19 de septiembre de 2012): 81–91. http://dx.doi.org/10.1017/s2045796012000480.

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Aims.The assessment of limitations in social capacities can be done with the Mini-ICF-APP, a rating scale built in reference to the International Classification of Functioning, Disability and Health (ICF). The aim of this study was to assess the reliability and the convergent validity of the Italian version of this scale.Methods.We recruited 120 consecutive patients diagnosed with schizophrenia, major depression, bipolar I disorder and anxiety disorders. Included measures were the Brief Psychiatric Rating Scale (BPRS), the Clinical Global Impression Scale (CGI-S), the Personal and Social Performance Scale (PSP) and the Social and Occupational Functioning Assessment Scale (SOFAS).Results.The median CGI-S and BPRS scores were 5 and 16.5. Mean Mini-ICF-APP total score was 18.1. Schizophrenics' Mini-ICF-APP score was higher, while that of anxious patients was lower than in the other diagnoses. Intra-class correlations (ICC) revealed a significant inter-rater agreement for total score (ICC 0.987) and for each item of the Mini-ICF-APP. The test–retest agreement was also highly significant (ICC 0.993). The total score of the Mini-ICF-APP obtained good negative correlations with PSP (rs = −0.767) and with SOFAS scores (rs = −0.790). The distribution items of the Mini-ICF-APP showed some skewness, indicating that self-care (item 12) and mobility (item 13) were amply preserved in most patients. The Mini-ICF-APP total score was significantly correlated with both CGI-S (rs = 0.777) and BPRS (rs = 0.729).Conclusions.As a short instrument, the Mini-ICF-APP scale seems to be well suited to everyday psychiatric practice as a means of monitoring changes in psychosocial functioning, in particular in schizophrenic patients.
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MANCILLA, JAIME G., MICHAEL FOWLER y PHILIP S. ULINSKI. "Responses of regular spiking and fast spiking cells in turtle visual cortex to light flashes". Visual Neuroscience 15, n.º 5 (mayo de 1998): 979–93. http://dx.doi.org/10.1017/s0952523898155190.

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Sharp electrodes were used to record light-evoked postsynaptic potentials (PSPs) from neurons in turtle visual cortex in an in vitro preparation of the geniculocortical pathway. Neurons were placed into four groups based on the firing patterns produced by intracellular current injections: regular spiking (RS), fast spiking (FS), intrinsic bursting (IB), and chattering (CH) cells. RS cells have been shown to be pyramidal cells while FS cells are typically interneurons. Light stimuli were diffuse, 1-s flashes of 640-nm light with intensities (I) varying from 0 to 104 photons μm−2 s−1. The response (R) in each case was the maximal amplitude of the light-evoked depolarizing PSP. Cells of all four types showed sigmoidal intensity–response (IR) functions with a linear rising phase for stimuli above the intensity threshold followed by saturation at high light intensities. Responses at high intensities were variable and some cells showed indications of supersaturation. Light-evoked PSPs had longer latencies and times-to-peak response in RS cells than they did in FS cells. RS cells fired action potentials as much as 200 ms later than did FS cells. Since responses recorded in RS cells at light intensities just above threshold are unlikely to involve contributions from other pyramidal cells, these data indicate that the geniculocortical or feedforward pathway to pyramidal cells has a high gain. The fact that FS cells fire well before RS cells suggests that feedforward inhibition plays a role in controlling the gain of the geniculocortical pathway.
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Foster, N. L., M. S. Aldrich, L. Bluemlein, R. F. White y S. Berent. "Failure of cholinergic agonist RS-86 to improve cognition and movement in PSP despite effects on sleep". Neurology 39, n.º 2 (1 de febrero de 1989): 257. http://dx.doi.org/10.1212/wnl.39.2.257.

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Olukanni, David O. y Ola O. Oresanya. "Progression in Waste Management Processes in Lagos State, Nigeria". International Journal of Engineering Research in Africa 35 (marzo de 2018): 11–23. http://dx.doi.org/10.4028/www.scientific.net/jera.35.11.

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One of the challenges of Lagos State is efficient and cost-effective solid waste management. This paper focuses on progress made in waste management operations in the State. An assessment to know how waste generation, collection, transportation and disposal have put demands on state resources, and its physical infrastructure was carried out. The state generates about 12,000 metric tons of waste daily (0.72kg/person/day). Due to limited budgetary allocation, the state government instituted the Lagos State Waste Management Authority (LAWMA) to perform supervisory roles and charged with the implementation, advocacy, monitoring and enforcement of waste management policies. As part of its roles, the agency enlisted Private Service Providers (PSP) for the purpose of appropriate billing of waste services. LAWMA centrally collects revenue and remits agreed portion of 60% of waste charges to individual PSP accounts in accordance to estimated waste collected. The state is focused on resource recovery programs such as composting, land filling and pelletizing of plastics and nylons. The implications (environmental, economic, social and financial) for managing solid waste gives credence to the renewal campaign for resource conservation and environmental sustainability. Thus, the 4 Rs of waste management – Reduction, Reuse, Recovery and Recycling are being demonstrated through establishment of compost production plant, championing of Waste-To-Wealth Initiatives and Renewable Energy (RE).
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Muresan, Raul C. y Cristina Savin. "Resonance or Integration? Self-Sustained Dynamics and Excitability of Neural Microcircuits". Journal of Neurophysiology 97, n.º 3 (marzo de 2007): 1911–30. http://dx.doi.org/10.1152/jn.01043.2006.

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We investigated spontaneous activity and excitability in large networks of artificial spiking neurons. We compared three different spiking neuron models: integrate-and-fire (IF), regular-spiking (RS), and resonator (RES). First, we show that different models have different frequency-dependent response properties, yielding large differences in excitability. Then, we investigate the responsiveness of these models to a single afferent inhibitory/excitatory spike and calibrate the total synaptic drive such that they would exhibit similar peaks of the postsynaptic potentials (PSP). Based on the synaptic calibration, we build large microcircuits of IF, RS, and RES neurons and show that the resonance property favors homeostasis and self-sustainability of the network activity. On the other hand, integration produces instability while it endows the network with other useful properties, such as responsiveness to external inputs. We also investigate other potential sources of stable self-sustained activity and their relation to the membrane properties of neurons. We conclude that resonance and integration at the neuron level might interact in the brain to promote stability as well as flexibility and responsiveness to external input and that membrane properties, in general, are essential for determining the behavior of large networks of neurons.
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Yaghi, Y. y H. Salim. "INTEGRATION OF RS/GIS FOR SURFACE WATER POLLUTION RISK MODELING. CASE STUDY: AL-ABRASH SYRIAN COASTAL BASIN". ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W7 (13 de septiembre de 2017): 949–54. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w7-949-2017.

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Recently the topic of the quality of surface water (rivers – lakes) and the sea is an important topics at different levels. It is known that there are two major groups of pollutants: Point Source Pollution (PSP) and non-point Source pollution (NPSP). Historically most of the surface water pollution protection programs dealing with the first set of pollutants which comes from sewage pipes and factories drainage. <br><br> With the growing need for current and future water security must stand on the current reality of the coastal rivers basin in terms of freshness and cleanliness and condition of water pollution. <br><br> This research aims to assign the NPS pollutants that reach Al Abrash River and preparation of databases and producing of risk Pollution map for NPS pollutants in order to put the basin management plan to ensure the reduction of pollutants that reach the river. This research resulted of establishing of Databases of NPSP (Like pesticides and fertilizers) and producing of thematic maps for pollution severity and pollution risk based on the pollution models designed in GIS environment and utilizing from remote sensing data. Preliminary recommendations for managing these pollutants were put.
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Alster, Piotr, Bartosz Migda, Natalia Madetko, Karolina Duszyńska-Wąs, Agnieszka Drzewińska, Ingeborga Charzyńska, Miłosz Starczyński, Ada Szepelska, Leszek Królicki y Andrzej Friedman. "The Role of Frontal Assessment Battery and Frontal Lobe Single-Photon Emission Computed Tomography in the Differential Diagnosis of Progressive Supranuclear Palsy Variants and Corticobasal Syndrome—A Pilot Study". Frontiers in Neurology 12 (4 de febrero de 2021). http://dx.doi.org/10.3389/fneur.2021.630153.

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Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are clinical syndromes classified as atypical parkinsonism. Due to their overlapping symptomatology, recent research shows the necessity of finding new methods of examination of these clinical entities. PSP is a heterogenic disease. PSP Richardson-Steele Syndrome (PSP-RS) and parkinsonism predominant (PSP-P) are the most common clinical variants of progressive supranuclear palsy syndrome. The different clinical course and life expectancy of PSP-RS and PSP-P stress the need of efficient examination in the early stages. The aim of the study was to evaluate the possible feasibility of the combined use of frontal assessment battery (FAB) and single-photon emission computed tomography (SPECT) in the differentiation of PSP-RS, PSP-P, and CBS. The findings show that FAB may be interpreted as a possible supplementary tool in the differential diagnosis of PSP-P and PSP-RS. The differences in SPECT are less pronounced. The study does not show any advantages of performing combined frontal SPECT and FAB in the differential examination of PSP and CBS. Moreover, PSP-RS and CBS, in a detailed evaluation of the frontal lobe, do not show any significant differences. This is a relatively small study which, however, highlights the relevant features of clinical examination of these rare entities.
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Song, Mengmeng, Maximilian Scheifele, Henryk Barthel, Thilo van Eimeren, Leonie Beyer, Ken Marek, Florian Eckenweber et al. "Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy". European Journal of Nuclear Medicine and Molecular Imaging, 22 de mayo de 2021. http://dx.doi.org/10.1007/s00259-021-05391-3.

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Abstract Purpose Dynamic 60-min positron emission tomography (PET) imaging with the novel tau radiotracer [18F]PI-2620 facilitated accurate discrimination between patients with progressive supranuclear palsy (PSP) and healthy controls (HCs). This study investigated if truncated acquisition and static time windows can be used for [18F]PI-2620 tau-PET imaging of PSP. Methods Thirty-seven patients with PSP Richardson syndrome (PSP-RS) were evaluated together with ten HCs. [18F]PI-2620 PET was performed by a dynamic 60-min scan. Distribution volume ratios (DVRs) were calculated using full and truncated scan durations (0–60, 0–50, 0–40, 0–30, and 0–20 min p.i.). Standardized uptake value ratios (SUVrs) were obtained 20–40, 30–50, and 40–60 min p.i.. All DVR and SUVr data were compared with regard to their potential to discriminate patients with PSP-RS from HCs in predefined subcortical and cortical target regions (effect size, area under the curve (AUC), multi-region classifier). Results 0–50 and 0–40 DVR showed equivalent effect sizes as 0–60 DVR (averaged Cohen’s d: 1.22 and 1.16 vs. 1.26), whereas the performance dropped for 0–30 or 0–20 DVR. The 20–40 SUVr indicated the best performance of all static acquisition windows (averaged Cohen’s d: 0.99). The globus pallidus internus discriminated patients with PSP-RS and HCs at a similarly high level for 0–60 DVR (AUC: 0.96), 0–40 DVR (AUC: 0.96), and 20–40 SUVr (AUC: 0.94). The multi-region classifier sensitivity of these time windows was consistently 86%. Conclusion Truncated and static imaging windows can be used for [18F]PI-2620 PET imaging of PSP. 0–40 min dynamic scanning offers the best balance between accuracy and economic scanning.
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Talai, Aron S., Jan Sedlacik, Kai Boelmans y Nils D. Forkert. "Utility of Multi-Modal MRI for Differentiating of Parkinson's Disease and Progressive Supranuclear Palsy Using Machine Learning". Frontiers in Neurology 12 (14 de abril de 2021). http://dx.doi.org/10.3389/fneur.2021.648548.

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Background: Patients with Parkinson's disease (PD) and progressive supranuclear palsy Richardson's syndrome (PSP-RS) often show overlapping clinical features, leading to misdiagnoses. The objective of this study was to investigate the feasibility and utility of using multi-modal MRI datasets for an automatic differentiation of PD patients, PSP-RS patients, and healthy control (HC) subjects.Material and Methods: T1-weighted, T2-weighted, and diffusion-tensor (DTI) MRI datasets from 45 PD patients, 20 PSP-RS patients, and 38 HC subjects were available for this study. Using an atlas-based approach, regional values of brain morphology (T1-weighted), brain iron metabolism (T2-weighted), and microstructural integrity (DTI) were measured and employed for feature selection and subsequent classification using combinations of various established machine learning methods.Results: The optimal machine learning model using regional morphology features only achieved a classification accuracy of 65% (67/103 correct classifications) differentiating PD patients, PSP-RS patients, and HC subjects. The optimal machine learning model using only quantitative T2 values performed slightly better and achieved an accuracy of 75.7% (78/103). The optimal classifier using DTI features alone performed considerably better with 95.1% accuracy (98/103). The optimal multi-modal classifier using all features also achieved an accuracy of 95.1% but required more features and achieved a slightly lower F1-score compared to the optimal model using DTI features alone.Conclusion: Machine learning models using multi-modal MRI perform significantly better than uni-modal machine learning models using morphological parameters based on T1-weighted MRI datasets alone or brain iron metabolism markers based on T2-weighted MRI datasets alone. However, machine learnig models using regional brain microstructural integrity metrics computed from DTI datasets perform similar to the optimal multi-modal machine learning model. Thus, given the results from this study cohort, it appears that morphology and brain iron metabolism markers may not provide additional value for classification compared to using DTI metrics alone.
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Yadav, R. C. y Jaya Yadav. "A novel launch of public- scientist- partnership (psp) project as engine for conserving natural resource and creating economic prosperity". Trends in Horticulture 1, n.º 4 (27 de agosto de 2018). http://dx.doi.org/10.24294/th.v1i4.772.

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Some developmental projects are created by people- private -partnership (PPP), particularly where recovery is acquirable by levying the users. Such PPPs are successful for construction of roads, bridges, running toilet facilities and conveyance facility in mode of use and pay. Likewise, public Scientist Partnership (PSPs) will be successful, where monitored impacts can be used to derive benefit. But, such example cases are not so popular in utilizing new research results and derive benefits from natural resources and enhance productivity. There exists need of similar partnership projects in research area. In this study modality of the PSP to create boost engine for natural resource conservation and bringing economic prosperity is established. A novel PSP launch was synthesized on useful food crop viz finger millet (Elusiane corcona (l)), known since long past, and now regaining popularity. It was possible to enhance additional annual production of 5.755 million Tonnes of finger millet grain, equivalent to additional income of Rs 11,510 crores. Against this the scientist partnership share was 0.49x million Tonnes grain and economic equivalency of Rs 992 crores, which was just 7-8%, with same level of input in agriculture. Additional benefits were sustainability of production and resources consecration, reduction of Green House Gas emission (GHGs), particularly nitrous oxide (N2O), largely emanating from agriculture and responsible for depletion of ozone layer. The finger millet stiff stem will be useable for production of ply-board filling material that will be innovative building material for housing and infrastructure developments. and making furniture.
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Dayal, Viswas, Ali Rajabian, Marjan Jahanshahi, Iciar Aviles-Olmos, Dorothy Cowie, Amy Peters, Brian Day et al. "Pedunculopontine Nucleus Deep Brain Stimulation for Parkinsonian Disorders: A Case Series". Stereotactic and Functional Neurosurgery, 4 de diciembre de 2020, 1–8. http://dx.doi.org/10.1159/000511978.

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<b><i>Background:</i></b> Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been investigated for the treatment of levodopa-refractory gait dysfunction in parkinsonian disorders, with equivocal results so far. <b><i>Objectives:</i></b> To summarize the clinical outcomes of PPN-DBS-treated patients at our centre and elicit any patterns that may guide future research. <b><i>Materials and Methods:</i></b> Pre- and post-operative objective overall motor and gait subsection scores as well as patient-reported outcomes were recorded for 6 PPN-DBS-treated patients, 3 with Parkinson’s disease (PD), and 3 with progressive supranuclear palsy (PSP). Electrodes were implanted unilaterally in the first 3 patients and bilaterally in the latter 3, using an MRI-guided MRI-verified technique. Stimulation was initiated at 20–30 Hz and optimized in an iterative manner. <b><i>Results:</i></b> Unilaterally treated patients did not demonstrate significant improvements in gait questionnaires, UPDRS-III or PSPRS scores or their respective gait subsections. This contrasted with at least an initial response in bilaterally treated patients. Diurnal cycling of stimulation in a PD patient with habituation to the initial benefit reproduced substantial improvements in freezing of gait (FOG) 3 years post-operatively. Among the PSP patients, 1 with a parkinsonian subtype had a sustained improvement in FOG while another with Richardson syndrome (PSP-RS) did not benefit. <b><i>Conclusions:</i></b> PPN-DBS remains an investigational treatment for levodopa-refractory FOG. This series corroborates some previously reported findings: bilateral stimulation may be more effective than unilateral stimulation; the response in PSP patients may depend on the disease subtype; and diurnal cycling of stimulation to overcome habituation merits further investigation.
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Santiago Júnior, Joel Ferreira y Eduardo Miyashita. "Anais do 11º Encontro do Grupo Brasileiro de Reciclagem em Prótese e Implante". ARCHIVES OF HEALTH INVESTIGATION 6 (14 de mayo de 2017). http://dx.doi.org/10.21270/archi.v6i0.2091.

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Adaptação marginal e análise da distribuição de tensões de próteses fixas sobre implantes de hexágono externo obtidas por diferentes sistemas CAD-CAM. Mello CC, Lemos CAA, Oliveira HFF, Cruz RS, Gomes JML, Santiago-Junior JF, Verri FR, Pellizzer EPAlvéolos frescos versus alvéolos cicatrizados para a instalação de implantes osseointegráveis. Uma revisão sistemática e meta-análise. Mello CC, Lemos CAA, Oliveira HFF, Cruz RS, Gomes JML, Verri FR, dos Santos DM, Goiato MC, Pellizzer EPAnalise biomecânica em MEF-3D dos efeitos da bicorticalização de implantes cone morse em próteses unitárias. Fernandes e Oliveira HF, Cruz RS, Lemos CAA, Batista VES, Mestrener LR, Gomes JML, Mello CC, Verri FRAnálise da adaptação marginal vertical em coroas cerâmicas feldspáticas confeccionadas através de diferentes sistemas CAD/CAM: aberto e fechado. Bueno CRS*, Kricheldorf F, Santiago Júnior JF, Nary Filho HAnálise da rugosidade superficial em resina acrílica reforçada com 1% de sílica silanizada com polimerização em micro-ondas. Cruz IDS, Silva PNF, Kamezawa LSG, Yamamoto LT, Almeida BM, Tango RNAnálise de diferentes configurações de protocolo mandibular com elementos finitos tridimensional. Alonso AA, Tribst JPM, Dal Piva AMO, Bottino MA, Tango RN, Borges ALSAnálise de uma superfície cerâmica a base de zircônia após diferentes técnicas de aplicação de glaze. Leite FPP, Castro FM, Pinto RAS, Malta NV, Miranda JS, de Carvalho RLAAnálise do comprimento, diâmetro e confecção das coroas em implantes de hexágono externo em maxila posterior pelo metodos dos elementos finitos 3D. Gomes JML, Lemos CAA, Batista VES, Mello CC, Cruz RS, Oliveira HFF, Verri FR, Pellizzer EPAnálise do nível de evidência cientifica em trabalhos sobre o uso das facetas diretas e indiretas. Dias ABG, Bessa GS, Neves AS, Garcia MG, Hayassy A, Souza FNAnálise do tipo de fresagem para pilares protéticos em implantes dentários. Cerqueira Filho JRA, Osorio LSA, Amaral WS, Bresaola MD, Santiago-Júnior JF, Nary Filho HAnálise in vitro da modulação da osseointegração em diferentes amostras de titânio poroso. Zutin EAL, Sartori EM, Carvalho LM, Mendonça DBS, Vasconcellos LMR, Carvalho YR, Cairo CAA, Mendonça GAnálise in vivo da modulação óssea em implantes de titânio com topografia de superfície em nanoescala. Carvalho LM, Sartori EM, Zutin EAL, Mendonça DBS, Smith L, Jepsen K, Krebsbach PK, Vasconcellos LMR, Mendonça GAnálise microtomográfica do processo de reparo periimplantar de ratas ovariectomizadas e tratadas com genisteína. Monteiro NG, Batista FRS, Gandolfo MIL, Freire A, Botacin PR, Faverani LP, Okamoto RAnálise morfométrica do osso reparacional pós-exodôntico de ratas ovariectomizadas tratadas com genisteína. Gandolfo MIL, Batista FRS, Monteiro NG, Freire AR, Botacin PR, Faverani LP, Okamoto RApresentações clínicas das desordens temporomandibulares e inter-relação com variações na curvatura de Spee. Silva BMF, Nascimento J, Souza RAO, França M, Garcia MG, Souza FNAumento ósseo em região posterior de mandíbulas atróficas: osso autógeno X biomaterial. Uma revisão sistemática e meta-análise. Sousa CA, Lemos CAA, Santiago-Júnior JF, Faverani LP, Pellizzer EPAvaliação biomecânica de diferentes pilares protéticos. Tribst JPM, Dal Piva AMO, Melo RM, Borges ALS, Souza ROA, Bottino MAAvaliação clínica da manutenção de alvéolos dentários humanos preenchidos por osso composto heterógeno. Araujo NJ, Natale Júnior V, Carvalho PSP, Bassi APF, Almeida JM, Souza FAAvaliação da atividade fotocatalítica e antibacteriana do TiO2 depositado na superfície do titânio comercialmente puro por meio de pulverização catódica. Pantaroto HN, Ricomini Filho AP, Silva JHD, Azevedo Neto NF, Sukotjo C, Rangel EC, Barão VARAvaliação da efetividade do Bio-oss® e Cerasorb® em defeitos peri-implantares. Análise biomecânica. Girotto FC, Justo YM, Queiroz TP, Luvizuto ER, Gulinelli JL, Garcia-Junior IR, Santos PLAvaliação do Biosilicato® em defeitos ósseos na calvária de ratos e sua influência no tecido ósseo neoformado. Munerato MS, Mendes GCB, Lima J, Duarte MAH, Couto MCR, Alcade M, Bossini PS,Matsumoto Biocompatibilidade e biofilme tri-espécies em superfícies de titânio tratados com plasmas para aplicações odontológicas. Matos AO, Ricomini-Filho AP, Beline T, Ogawa ES, Oliveira BEC, Almeida AB, Nociti Junior FH, Rangel EC, da Cruz NC, Sukotjo C, Mathew MT, Barao VARCaracterização de filmes finos de carbono tipo diamante depositado em substrato de polimetilmetacrilato. Souza FN, Evers M, Nachez L, Almeida CC, Franceschin Filho DF, Tiossi RCaracterização superficial e da resistência à flexão biaxial de cerâmica Y-TZP translúcida submetida a diferentes condicionamentos de superfície. Bittar BF, Castro FM*, Miranda JS, Simões AC, Souza, ROA, Leite, FPP, Pinto RASCirurgia sem retalho e carga imediata em overdenture mandibular sobre um implante: relato de 6 anos de acompanhamento. Longhini D, Rocha COM, Pereira RP, Adabo GL, Arioli-Filho JNComplicações de próteses internas de PMMA comparada a outros materiais. Revisão sistemática e meta-análise. Maior JRS, Leão RS, Lemos CAA, EP Pelizzer, Montes MJR, Moraes SLDComportamento biomecânico de diferentes próteses cimentadas sobre implante. Dal Piva AMO, Tribst JPM, Rodrigues VA, Borges ALS, Bottino MAComportamento biomecânico de implantes instalados em diferentes angulações. Datte CE, Tribst JPM, Rodrigues VA, Dal Piva AMO, Nishioka RS, Borges ALSComportamento biomecânico de prótese fixa sobre implante de três elementos com pôntico em cantilever. Estudo pelo MEF-3D. Cruz RS, de Souza Batista VE, Lemos CCA, Fernandes e Oliveira HF, Gomes JML, Mestrener LR, Pellizzer EP, Verri FRComportamento biomecânico de restaurações Endocrown: influência da espessura da restauração e do direcionamento da carga mastigatória. Fonseca GF, Tribst JPM, Dal Piva AMO, Borges ALSDesenvolvimento de ligas contendo Zr e Nb para implantes dentários. Cordeiro JM, Beline T, Ribeiro ALR, Rangel EC, Cruz NC, Landers R, Faverani LP, Vaz LG, Fais LMG, Grandini CR, Barão VARDiferentes protocolos de condicionamento podem alterar as propriedades de uma cerâmica híbrida? Miranda JS*, Monteiro JB, Silva PNF, Valera MC, Bresciani E, Marinho RMDistribuição de tensão em retentores intrarradiculares fabricados por CAD/CAM de diferentes módulos de elasticidade. Andrade GS,Tribst JPM, Santin DC, Dal Piva AMO, Bottino MA, Borges ALSEfeito da adição de 1% de sílica silanizada no módulo elástico da resina acrílica ativada por microondas em diferentes ciclos de polimerização. Almeida BM, Silva PNF, Kamezawa LSG, Yamamoto LT, Barros IM, Tango RNEfeito da escovação associada à irrigação oral na manutenção dos tecidos peri-implantares e overdentures. Salles MM, Oliveira VC, Macedo AP, Paranhos HFOEfeito da esplintagem de implantes curtos na região posterior de maxila: estudo pela MEF-3D. Mestrener LR, Oliveira HFF, Cruz RS, Lemos CAA, de Souza Batista VE, Pellizzer EP, Verri FREfeito da overdenture mandibular na autopercepção da saúde bucal e eficiência mastigatória de usuários de prótese. Rocha COM, Pereira RP, Longhini D, Bonafé FSS, Campos JADB, Arioli Filho JNEfeito da pressão, tempo de pós-prensagem e ciclo de polimerização sobre o grau de conversão de resina acrílica termoativada: abordagem para uso em próteses internas. Leão RS, Moraes SLD, Aquino KAS, Isolan CP, Montes MAJREfeito da radiação ionizante na resistência mini-flexural e caracterização estrutural de cimentos resinosos protegidos com cerâmicas Y-TZP. Silva PNF, Gonçalez OL, Manea S, Yamamoto LT, Cruz IDS, Barros IM, Tango RNEfeito da sacarose na formação de biofilme no titânio: estudo in situ. Souza JGS, Cury JA, Ricomini-Filho AP, Faveri M, Feres M, Barão VAREfeito das conexões internas na distribuição de tensões em implantes de diâmetro regular. Pereira IT, Cerqueira Filho JR, Lemos CAA, Batista VES, Almeida DAF, Verri FR, Pellizzer EP, Santiago Júnior JFEfeito de protocolos de envelhecimento na resistência de uma cerâmica feldspática. Martins GB, Yamamoto LT, Silva PNF, Tango RNEfeito do auxílio do google docs na aplicação do método ativo peer instruction no aprendizado de conceitos de montagem de modelos em articulador semi-ajustável. Servera MSD, Marques R, Filho JEP, Santos FP, Garcia MG, Souza FNEfeito do posicionamento tripoidal em implantes curtos instalados na região posterior de maxila. Estudo pela MEF-3D. de Souza Batista VE, Cruz RS, Fernandes e Oliveira HF, Gomes JML, Lemos CAA, Verri FR, Pellizzer EPEfetividade dos tratamentos não cirúrgicos de periimplantite: uma revisão sistemática. Araujo NJ, Gusman DJR, Matheus HR, Faleiros PL, Novaes VCN, Almeida JMEnxerto de tecido conjuntivo subepitelial para otimização da estética periimplantar. Araujo NJ, Faleiros PL, Gusman DJR, Oliveira FLP, Fiorin LG, Almeida JMEsquemas de oclusão em próteses totais: uma revisão. Contreras LPC, Alonso AA, Tango RN, Paes Junior TJAEstudo clínico retrospectivo de 3 anos acompanhamento de coroas cerâmicas unitárias confeccionadas por sistema CAD/CAM chair-side. Karam FK, Reis TA, Zancopé K, Resende CCD, Prado CJ, Neves FDExtensometria: o efeito de mesa oclusal larga e do posicionamento de implantes em PPF de 3 elementos implanto-suportada. Vasconcellos LGO, Rodrigues VA, Nishioka GNM, Vasconcellos LMR, Andretta-Filho OD, Kojima AN, Nishioka RSFeixe de luz auxiliar aplicado na remoção de corpo estranho em seio maxilar. Aplicação em cirurgia e implantodontia. Polo TOB, de Lima VN, Momesso GAC, Bassi APF, Faverani LPImpacto da reabilitação oral na qualidade de vida de um indivíduo com características da Síndrome de Kelly. Dias ABG, Bessa GS, Vieira GS, Hayassy A, Garcia MG, Souza FNImpacto da reabilitação oral sobre implantes em pacientes com anomalias craniofaciais associadas à fissura labiopalatina. Lino LFO, Lopes MMW, Azevedo RMG, Tavano RDA, Pinto JHN, Lopes JFSImpacto de diferentes tipos ósseos para a implantodontia: Uma revisão sistemática. Holobenko L,Kudo GAH, Loureiro NB, Pereira IT, Oliveira RG, Verri FR, Pellizzer EP, Santiago Junior JFImplantes curtos versus implantes convencionais com elevação do seio maxilar. Uma revisão sistemática e meta-análise. Cruz RS, Lemos CAA, Mello CC, Oliveira HFF, Gomes JML, de Souza Batista VE, Pellizzer EP, Verri FRImplantes de diâmetro estreito de titanium-zirconium. Revisão sistemática e metanálise. Iegami CM, Uehara PN, Sesma N, Panutti CM, Laganá DC, Tamaki R, Tortamano Neto P, Mukai MKImplantes instalados em pacientes com fissura labiopalatina. Revisão Sistemática. Oshiro TY, Magalhães KMF, Lopes JFS, Azevedo RMG, Minatel L, Santiago Júnior JF, Pinto JHNInfluência da estrutura interna de coroas temporárias na distribuição de tensões em implantes unitários. Rodrigues VA, Tribst JPM, Dal Piva AMO, Nishioka RS, Bottino MA, Borges ALInfluência da rigidez dos cimentos resinosos na distribuição de tensão em prótese fixa adesiva. Penteado MM, Jurema ALB, Tribst JPM, Saavedra GSFA, Borges ALSInfluência de escâneres CAD/CAM na adaptação marginal de infraestruturas em zircônia implanto-suportadas. Resende CCD, Carneiro TAPN, Karam FKK, Neves FDNInfluência do laser de baixa potência na terapia de reparo de defeitos ósseos maxilo-faciais. Revisão Sistemática. Fernandes e Oliveira HF, Santinoni CS, Batista VES, Lemos CAA, Cruz RS, Mello CC, Martim BEA, Verri FRInfluência do nível do tecido ósseo na distribuição de tensões. Análise pelo método dos elementos finitos 3D. Lemos CAA, Verri FR, Batista VES, Mello CC, Cruz RS, Fernandes e Oliveira HF, Gomes JML, Mestrener LR, Pellizzer EPInfluência do tipo de liquido de manipulação na dureza e tenacidade à fratura de uma cerâmica feldspática. Moura GS, Takahashi T, Ramos GF, Campos T, Özcan M, Melo RMM, Amaral MInstalação de implantes em região distal para converter pacientes portadores de próteses parciais removíveis classe I para classe III de Kennedy: revisão sistemática. Karam FK, Zancopé K, Abraão GM, Neves FDInstalação de implantes zigomáticos em maxila atrófica em paciente portador de insuficiência renal. Relato de caso. Momesso GAC, Lima VN, Queiroz SBF, Polo TOB, Sousa CA, Assunção WG, Faverani LPLaserterapia de baixa potência e fator de crescimento epidérmico em fibroblastos gengivais cultivados sobre titânio. Pansani TN, Basso FG, Hebling J, de Souza Costa CAMockup imediato em resina composta para confecção de laminados cerâmicos. Castro FM, Leite FPP, Pinto RAS, Pazinatto RBNível de evidência científica em trabalhos publicados sobre o bruxismo. Cardozo BB, Oliveira FP, Quelhas MC, Garcia MG, França L, Souza FNO impacto de diferentes estratégias de fresagem na adaptação de coroas CAD/CAM – avaliação 3D. Piras FF, Ferruzzi F, Ferrairo BM, Borges AFS, Bonfante EA, Rubo JHOsseointegração de implantes com diferentes superfícies: estudo in vivo. Vasconcellos LMR, Beraldo JM, Villaça-Carvalho MF, Moraes MEL, Vasconcellos LGO, Regone NN, Acciari HAPrincípios odontológicos na harmonização do sorriso: laminados cerâmicos. Barcellos ASP, Barchetta NF, Monteiro JB, Cabral G, Melo RMM, Kimpara ET, Saavedra GSFAPróteses overdentures retidas por mini implantes. Uma revisão sistemática. Gomes JML, Lemos CAA, Batista VES, Mello CC, Santiago-Júnior JF, Cruz RS, Oliveira HFF, Verri FR, Pellizzer EPRanelato de estrôncio melhora a resposta de osseointegração em ratas com deficiência de estrógeno. Yogui FC, Coléte JZ, Batista FRS, Gomes-Ferreira PHS, Momesso GAC, Faverani LP, Okamoto RReabilitação com prótese parcial removível associada a implantesapós lesão por arma de fogo: 5 anos de acompanhamento. Gomes JML, de Faria Almeida DA, Goiato MC, Batista VES, Lemos CAA, Mello CC, Verri FR, Pellizzer EPReabilitação de anquilose condilar bilateral das articulações temporomandibulares com próteses internas em PMMA. Leão RS, Monteiro JLGC, Barbosa LM, Carneiro SCAS, Moraes SLD, Vasconcelos BCEReabilitação estética minimamente invasiva com abordagem multidisciplinar. Relato de caso. Mestrener LR, Oliveira HFF, Cruz RS, Lemos CAA, de Souza Batista VE, Mello CC, Almeida JM, Verri FRReabilitação estético funcional: conjugação de restaurações em resina direta, laminados ultrafinos e onlays cerâmicas. Miranda JS, Sato TP, Penteado MM, Kimpara ET, Moura Jr JR, Prats FS, Cabral GReabilitação protética com componentes dinâmicos – relato de caso. Resende CCD, Carneiro TAPN, Pereira LM, Tavares LN, Karan FK, Neves FDNReabilitação provisória estética unitária imediata sobre implante com enxerto de tecido conjuntivo associado - relato de caso. Cruz RS, Fernandes e Oliveira HF, Mestrener LR, Lemos CAA, Gomes JML, de Souza Batista VE, Mello CC, Verri FRResistência à flexão biaxial de resinas nanocerâmicas e Bulk Fill antes e após o envelhecimento. Piza MMT, Beltramini I, Machado CM, Jalkh EBB, Hirata R, Coelho PG, Bonfante EAResistência à flexão biaxial de uma cerâmica feldspática confeccionada com diferentes líquidos de manipulação. Takahashi T, Moura GS, Ramos GF, Campos T, Özcan M, Melo RMM, Amaral MResistência ao pull-out de coroas CAD/CAM cimentadas em pilares do tipo Ti-base. Machado CM, Lopes ACO, Jalkh EBB, Da Silva CPE, Piza MMT, Bonjardim LR, Bonfante EAResistência de união de pinos de fibra de vidro submetidos a diferentes protocolos de cimentação. Pinto RAS, Castro FM, de Landa FV, Miranda JS, de Carvalho RF, Kimpara ET, Leite FPPResistência de união entre dois cimentos resinosos autocondicionantes e zircônia Y-TZP submetida a tratamento superfície. Casado BGS, Beltrão MGP, Feltrin PP, Inoue RT, Moraes SLD, Zanetti RVTécnica de expansão óssea modificada para pré-maxila atrófica: um estudo piloto caso controle. Caetano AS, Damante CA, Bizelli VF, Junior Moraes EFMToxina botulínica como terapia para o bruxismo: existem evidências para sua indicação? Câmara-Souza MB, De la Torre Canales G, Amaral CF, Rodrigues Garcia RCM, Manfredini DTratamento com ranelato de estrôncio melhora atividade celular e microarquitetura óssea alveolar em ratas osteopênicas. Momesso GAC, Colete JZ, Ervolino ACS, Hassumi JS, Puttini IO, Polo TOB, Faverani LP, Okamoto RTratamento de peri-implantite com complicação estética em sorriso gengival: relato de caso. Caetano AS, Bizelli VF, Junior Moraes EFMTratamento multidisciplinar: associação entre ortodontia, implantodontia e prótese. Relato de um caso. Lima DR, Lima FR, Pazinato R, Pedroso JFTrauma e instabilidade oclusal como fatores etiológicos da osteoartrite nas ATM: relato de caso. Pinto RAS, Dias IM, Bonato LL, Castro FM, Leite FPP, Guimarães JPUma abordagem não cirúrgica de 5 semanas para hiperplasia fibrosa causada por prótese. Lopes DM, Iegami CM, Lopes DM, Tormamano P, Tamaki RUso de implantes com gengiva cerâmica em reabilitação oral estética anterior. Fernandes e Oliveira HF, Cruz RS, Lemos CAA, Mello CC, Batista VES, Mestrener LR, Gomes JML, Verri FRUtilização do β-tricálcio fosfato para preenchimentos de defeitos peri-implantares e alvéolos frescos: caso clínico. Casimiro GHS, Marques DO, Margonar R, Faloni APS, Queiroz TP, Gulinelli JL, Santos PL
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