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Artículos de revistas sobre el tema "Rat nu des sables"

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Publicado: 19 de octubre de 2024

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1

Ridel, P. R., C. Auriault, F. Darcy, et al. "Protective role of IgE in immunocompromised rat toxoplasmosis." Journal of Immunology 141, no. 3 (1988): 978–83. http://dx.doi.org/10.4049/jimmunol.141.3.978.

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Abstract In contrast to euthymic adult Fischer rats, immunocompromised Nu/Nu animals develop a lethal infection when inoculated with the RH strain of the protozoan Toxoplasma gondii. However, a significant period of survival is obtained when Nu/Nu rats are passively transferred with sera from 28-day infected Fischer +/+ (euthymic) animals. Specific IgE are involved since IgE-depleted sera are unable to afford such a protection. Only excreted/secreted Ag or living tachyzoites are able to induce a significant protective IgE response in intact animals. In addition, platelets or, to a lesser exten
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2

Ohashi, Takashi, Shino Hanabuchi, Hirotomo Kato, et al. "Induction of Adult T-Cell Leukemia-Like Lymphoproliferative Disease and Its Inhibition by Adoptive Immunotherapy in T-Cell-Deficient Nude Rats Inoculated with Syngeneic Human T-Cell Leukemia Virus Type 1-Immortalized Cells." Journal of Virology 73, no. 7 (1999): 6031–40. http://dx.doi.org/10.1128/jvi.73.7.6031-6040.1999.

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ABSTRACT Human T-cell leukemia virus type 1 (HTLV-1) has been shown to be the etiologic agent of adult T-cell leukemia (ATL), but the in vivo mechanism by which the virus causes the malignant transformation is largely unknown. In order to investigate the mechanisms of HTLV-1 leukemogenesis, we developed a rat model system in which ATL-like disease was reproducibly observed, following inoculation of various rat HTLV-1-immortalized cell lines. When previously established cell lines, F344-S1 and TARS-1, but not TART-1 or W7TM-1, were inoculated, systemic multiple tumor development was observed in
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3

Cordonnier, Marie-Neige. "Qui es-tu, rat-taupe nu ?" Pour la Science N° 551 – septembre, no. 9 (2023): 42–45. http://dx.doi.org/10.3917/pls.551.0042.

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4

del Marmol, Delphine. "Les pouvoirs extraordinaires du rat-taupe nu." Pour la Science N° 551 – septembre, no. 9 (2023): 34–41. http://dx.doi.org/10.3917/pls.551.0034.

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5

Benazzoug, Y., B. Chaouad, F. Zerrouk, et al. "Impact d’une hyperhomocystéinémie sur la structure hépatique du rat des sables, Psammomys obesus." Nutrition Clinique et Métabolisme 30, no. 3 (2016): 254. http://dx.doi.org/10.1016/j.nupar.2016.09.072.

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6

Benmouloud, A., S. Zahaf, F. Khammar, and Z. Amirat. "P2-160 - Interaction testicule-corticosurrénale, chez le rat des sables psammomys obesus adulte." Annales d'Endocrinologie 67, no. 5 (2006): 531–32. http://dx.doi.org/10.1016/s0003-4266(06)72991-2.

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7

Suzuki, T., N. Suzuki, and T. Hosoya. "Limited proteolysis of rat liver nucleolin by endogenous proteases: effects of polyamines and histones." Biochemical Journal 289, no. 1 (1993): 109–15. http://dx.doi.org/10.1042/bj2890109.

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Nucleolin is a major nucleolar phosphoprotein and is presumably involved in rDNA transcription and ribosome biosynthesis. This protein is known to be very labile and to be cleaved by endogenous proteases into many small peptides. We found that, when rat liver nucleolar suspension (Nu-1) or nucleolin-rich extract (Nu-2) was incubated under conventional conditions, polyamines and histones interacted with the nucleolin to lead to its preferential degradation to 60 kDa phosphopeptide (p60). The peptide p60 was identified as a peptide containing the N-terminal half of the nucleolin molecule, as jud
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8

Omari, N. "P227 Syndrome métabolique chez le rat des sables (Psammomys obesus) : dysfonctionnement de l’axe corticotrope." Diabetes & Metabolism 36 (March 2010): A92. http://dx.doi.org/10.1016/s1262-3636(10)70375-x.

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9

Boubekri, A., T. Gernigon, N. Kaci, F. Khammar, and J. Exbrayat. "Plasticité des cellules lactotropes au cours du cycle de reproduction du rat des sables." Annales d'Endocrinologie 74, no. 4 (2013): 432. http://dx.doi.org/10.1016/j.ando.2013.07.692.

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10

Menad, R., S. Smaï-Hamdidouche, T. Gernigon, and J. M. Exbrayat. "Les récepteurs des œstrogènes dans les canaux efférents du rat des sables, psammomys obesus." Annales d'Endocrinologie 76, no. 4 (2015): 498–99. http://dx.doi.org/10.1016/j.ando.2015.07.665.

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11

Taguchi, O., T. Takahashi, M. Seto, R. Namikawa, M. Matsuyama, and Y. Nishizuka. "Development of multiple organ-localized autoimmune diseases in nude mice after reconstitution of T cell function by rat fetal thymus graft." Journal of Experimental Medicine 164, no. 1 (1986): 60–71. http://dx.doi.org/10.1084/jem.164.1.60.

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Restoration of T cell function of athymic BALB/c nu/nu mice was investigated after transplantation of xenogeneic thymic rudiments from 15-d-old embryonic rats into kidney subcapsule. The rudiments developed well and formed a proper thymus structure composed of donor epithelia and host lymphocytes. Examination of antibody responses to SRBC revealed that approximately half the normal number of indirect PFCs were observed. Skin grafts from syngeneic BALB/c mice and thymic donor rat strains were accepted, whereas those from allogeneic mice and the rats of other than donor strains were vigorously r
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12

Dahmani, Y., J. Catala, F. Fichaux, et al. "Effects du gliclazide chez le lapin diabétique et le rat des sables diabétique et hypercholestérolémique." Reproduction Nutrition Développement 30, no. 1 (1990): 129. http://dx.doi.org/10.1051/rnd:19900124.

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13

Boubekri, A., R. Menad, T. Gernigon, F. Khammar, and J. M. Exbrayat. "Immunoexpression de l’aromatase au niveau de l’appareil reproducteur mâle et femelle du rat des sables." Annales d'Endocrinologie 76, no. 4 (2015): 497. http://dx.doi.org/10.1016/j.ando.2015.07.660.

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14

Boubekri, A., and T. Gernigon. "Caractérisation des gonades du rat des sables, Psammomys obesus, au cours du repos saisonnier de reproduction." Annales d'Endocrinologie 75, no. 5-6 (2014): 421. http://dx.doi.org/10.1016/j.ando.2014.07.506.

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15

Zuhri, Ach. "PROFITABILITAS KSPPS BMT NU CABANG LARANGAN PAMEKASAN TAHUN 2018." Jurnal Tabarru': Islamic Banking and Finance 3, no. 2 (2020): 262–68. http://dx.doi.org/10.25299/jtb.2020.vol3(2).5819.

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Profitabilitas merupakan salah satu cara dalam mengukur dan melihat besarnya laba, untuk mengetahui seberapa efisien suatu perusahaan dalam menjalankan usahanya. Cara mengetahui besar kecilnya tingkat profitabilitas bank yaitu dengan menggunakan Return on Assets (ROA), ROA menunjukkan kapabilitas perusahaan menggunakan seluruh aktiva yang perusahaan miliki dalam menghasilkan keuntungan setelah pajak. Rasio ini sangat penting bagi pihak manajemen perusahaan untuk mengevaluasi efektivitas dan efisiensi usaha dalam mengelola seluruh pendapatan perusahaan. BMT NU saat ini telah tergolong berkemban
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16

Chen, Xiu-Wen, Na Ni, Xiao-Jun Xie, et al. "Sympathetic Reinnervation of Intact and Upper Follicle Xenografts into BALB/c-nu/nu Mice." Life 13, no. 11 (2023): 2163. http://dx.doi.org/10.3390/life13112163.

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Increasing concerns about hair loss affect people’s quality of life. Recent studies have found that sympathetic nerves play a positive role in regulating hair follicle stem cell activity to promote hair growth. However, no study has investigated sympathetic innervation of transplanted follicles. Rat vibrissa follicles were extracted and implanted under the dorsal skin of BALB/c-nu/nu mice using one of two types of follicles: (1) intact follicles, where transplants included bulbs, and (2) upper follicles, where transplants excluded bulbs. Follicular samples were collected for hematoxylin and eo
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17

Kocic, G., J. Nikolic, T. Jevtovic-Stoimenov, et al. "L-Arginine Intake Effect on Adenine Nucleotide Metabolism in Rat Parenchymal and Reproductive Tissues." Scientific World Journal 2012 (2012): 1–4. http://dx.doi.org/10.1100/2012/208239.

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L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence. The aim of the present paper was to estimate the activity of the enzymes of adenine nucleotide metabolism:5′-nucleotidase (5′-NU), adenosine deaminase (ADA), AMP deaminase, and xanthine oxidase (XO), during dietary intake of L-arginine for a period of four weeks of male Wistar rats. Adenosine concentration in tissues is maintained by the relative activitie
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18

Suit, Herman D., Sara Rockwell, Anthony Zeitman, et al. "Quantitative transplantation assays of the rat rhabdomyosarcoma BA1112 isografts into the WAG/Rij Y rat and xenotransplantation into the athymic NCr(nu/nu) nude mouse." European Journal of Cancer and Clinical Oncology 25, no. 10 (1989): 1463–66. http://dx.doi.org/10.1016/0277-5379(89)90105-3.

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19

Ohashi, Takashi, Shino Hanabuchi, Hirotomo Kato, et al. "Prevention of Adult T-Cell Leukemia-Like Lymphoproliferative Disease in Rats by Adoptively Transferred T Cells from a Donor Immunized with Human T-Cell Leukemia Virus Type 1 Tax-Coding DNA Vaccine." Journal of Virology 74, no. 20 (2000): 9610–16. http://dx.doi.org/10.1128/jvi.74.20.9610-9616.2000.

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ABSTRACT Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) in infected individuals after a long incubation period. To dissect the mechanisms of the development of the disease, we have previously established a rat model of ATL-like disease which allows examination of the growth and spread of HTLV-1 infected tumor cells, as well assessment of the effects of immune T cells on the development of the disease. In the present study, we induced HTLV-1 Tax-specific cytotoxic T lymphocyte (CTL) immunity by vaccination with Tax-coding DNA and examined the effects of the DNA v
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20

Ghoul, A., N. Kaci-Ouchefoun, F. Zerrouk, B. Chaouad, J. M. Exbrayat, and Y. Benazzoug. "Hyperhomocystéinémie et récepteurs des œstrogènes au niveau de la vésicule séminale du rat des sables, Psammomys obesus." Annales d'Endocrinologie 79, no. 4 (2018): 256. http://dx.doi.org/10.1016/j.ando.2018.06.173.

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21

Lestaevel, P., S. Grison, G. Favé, et al. "Assessment of the Central Effects of Natural UraniumviaBehavioural Performances and the Cerebrospinal Fluid Metabolome." Neural Plasticity 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/9740353.

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Natural uranium (NU), a component of the earth’s crust, is not only a heavy metal but also an alpha particle emitter, with chemical and radiological toxicity. Populations may therefore be chronically exposed to NU through drinking water and food. Since the central nervous system is known to be sensitive to pollutants during its development, we assessed the effects on the behaviour and the cerebrospinal fluid (CSF) metabolome of rats exposed for 9 months from birth to NUvialactation and drinking water (1.5, 10, or 40 mg·L−1for male rats and 40 mg·L−1for female rats). Medium-term memory decrease
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22

Ikeda, H., O. Taguchi, T. Takahashi, G. Itoh, and Y. Nishizuka. "L3T4 effector cells in multiple organ-localized autoimmune disease in nude mice grafted with embryonic rat thymus." Journal of Experimental Medicine 168, no. 6 (1988): 2397–402. http://dx.doi.org/10.1084/jem.168.6.2397.

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Rat thymic grafts reconstituted T cell functions of BALB/c nude (nu/nu) mice to a considerable degree, but multiple organ-localized autoimmune diseases such as oophoritis and thyroiditis generally developed. The effector cell population in this autoimmune model was studied by adoptive transfer of the lesions into syngeneic nude mice. The transfer activity was not diminished when spleen cells were incubated with antiserum against rat cell antigen and C, but the activity was completely vanished by incubation with anti-Thy-1.2 plus C, indicating that the effector cells are T cells of mouse origin
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23

Zuhri, Ach. "Analisis Promotion Mix pada Produk SIDIK Fathonah di BMT NU Cabang Ganding." Economic and Education Journal (Ecoducation) 2, no. 1 (2020): 1–10. http://dx.doi.org/10.33503/ecoducation.v2i1.729.

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Penelitian ini menggunakan metode pendekatan kualitatif, informan adalah karyawan Baitul Maal wat Tamwil (BMT) NU Cabang Ganding. Sedangkan tehnik pengumpulan datanya yaitu dengan observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa pertama; Variabel promotion mix sudah diterapkan di BMT NU Cabang Ganding, advertising (periklanan) berupa pemasangan spanduk dan penyebaran browsur, sales promotion dengan cara mendatangi langsung serta melakukan demonstrasi produk SIDIK Fathonah kepada para siswa, publicity dengan cara mengadakan pengajian saat Rapat Anggota Tahunan (RAT) dan
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24

Dawson, T. P., R. Gandhi, M. Le Hir, and B. Kaissling. "Ecto-5'-nucleotidase: localization in rat kidney by light microscopic histochemical and immunohistochemical methods." Journal of Histochemistry & Cytochemistry 37, no. 1 (1989): 39–47. http://dx.doi.org/10.1177/37.1.2535703.

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We demonstrated the distribution pattern of ecto-5'-nucleotidase (5'-Nu) in rat kidney by enzymatic activity (lead salt precipitation) and by immunohistochemistry with a polyclonal antibody raised in rabbits. Enzyme activity was found in the brush border of the proximal tubule, highest in the P1 segments with decreasing intensity in the P2 segments and weakest in P3 segments in the medullary rays of the cortex. The P3 segments of the outer stripe showed slightly higher activity. Activity was also apparent in the intercalated cells in the connecting tubule and collecting duct, whereas all other
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25

Fontán, J. Julio Pérez, Daniel N. Cortright, James E. Krause, et al. "Substance P and neurokinin-1 receptor expression by intrinsic airway neurons in the rat." American Journal of Physiology-Lung Cellular and Molecular Physiology 278, no. 2 (2000): L344—L355. http://dx.doi.org/10.1152/ajplung.2000.278.2.l344.

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Tachykinins and their receptors are involved in the amplification of inflammation in the airways. We analyzed the expression of preprotachykinin-A (PPT-A) and neurokinin-1 (NK-1) receptor genes by intrinsic airway neurons in the rat. We also tested the hypothesis that PPT-A-encoded peptides released by these neurons fulfill the requisite role of substance P in immune complex injury of the lungs. We found that ganglion neurons in intact and denervated airways or in primary culture coexpress PPT-A and NK-1 receptor mRNAs and their protein products. Denervated ganglia from tracheal xenografts ( n
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26

Menad, R., L. Lakabi, S. Smaï-Hamdidouche, et al. "Impact de la saison sur l’immunodistribution des récepteurs des œstrogènes dans le testicule du rat des sables, Psammomys obesus." Annales d'Endocrinologie 79, no. 4 (2018): 252–53. http://dx.doi.org/10.1016/j.ando.2018.06.162.

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27

Krowicki, Zbigniew K., Nicole A. Nathan, and Pamela J. Hornby. "Gastric motor and cardiovascular effects of insulin in dorsal vagal complex of the rat." American Journal of Physiology-Gastrointestinal and Liver Physiology 275, no. 5 (1998): G964—G972. http://dx.doi.org/10.1152/ajpgi.1998.275.5.g964.

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Insulin-binding sites exist in the lower brain stem of the rat, raising the possibility that the circulating hormone may have cardiovascular and gastric effects at this site. Therefore, we investigated the autonomic effects of applying rat insulin to the surface of the dorsal medulla (0.3 and 3 μU/rat) or microinjecting it into the dorsal vagal complex (DVC) (0.1–10 nU/site) in anesthetized rats. Application of rat insulin to the surface (3 μU/rat) and its microinjection into the DVC (1 and 10 nU/site) both evoked marked, albeit transient, increases in intragastric pressure, pyloric and greate
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28

Pieger, Katharina, Verena Schmitt, Carina Gauer, et al. "Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation." Biomolecules 12, no. 8 (2022): 1108. http://dx.doi.org/10.3390/biom12081108.

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Alpha synuclein (aSyn) and its aggregation are crucial for the neurodegeneration of Parkinson’s disease (PD). aSyn was initially described in the nucleus and presynaptic nerve terminals. However, the biology of nuclear aSyn and the link of aSyn between subcellular compartments are less understood. Current knowledge suggests the existence of various aSyn species with distinct structural and biochemical properties. Here, we identified a C-terminal-targeting aSyn antibody (Nu-aSyn-C), which has a high immunoaffinity towards aSyn in the nucleus. Comparing the Nu-aSyn-C antibody to aSyn antibodies
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29

Bachmann, S., M. Le Hir, and K. U. Eckardt. "Co-localization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin." Journal of Histochemistry & Cytochemistry 41, no. 3 (1993): 335–41. http://dx.doi.org/10.1177/41.3.8429197.

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In adults, the kidneys are the major site of production of the glycoprotein hormone erythropoietin (EPO), but the type of renal cell producing EPO has not yet been identified. In the present study we used non-radioactive in situ hybridization with a digoxigenin-labeled cRNA probe to localize cells that produce erythropoietin (EPO) in kidneys of anemic rats. Cryostat sections from both native and perfusion-fixed tissue were used. Cells containing EPO mRNA were found exclusively in the peritubular space of the renal cortex. Using high-resolution interference contrast optics, we found that cells
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30

Susan, Costantini, Vasu Gautam, Salvatore Maria, Leila Birolo, Sara Longobardi, and Colonna Giovanni. "Conformational Analysis of Rat Seminal Vesicle Secretory Protein 4, an Intrinsically Disordered Protein Having Interesting Pharmacological Properties." International Journal of Chemistry 7, no. 2 (2015): 133. http://dx.doi.org/10.5539/ijc.v7n2p133.

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Rat seminal vesicle protein 4 (RSV4) is a member of the seminal vesicle protein family present in rats, 90 residues long. When secreted, it is involved in many functions related to the reproduction ranging from semen coagulation to sperm capacitation, but its fragments have also shown in vitro pharmacological properties such as anti-inflammatory and pro-coagulant activity, important in the cancer development. However, no three-dimensional model of this protein is yet available probably because of the presence of intrinsic disorder in the structure. In this article we report structural studies
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31

Frei, K., S. Bodmer, C. Schwerdel, and A. Fontana. "Astrocytes of the brain synthesize interleukin 3-like factors." Journal of Immunology 135, no. 6 (1985): 4044–47. http://dx.doi.org/10.4049/jimmunol.135.6.4044.

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Abstract Interleukin 3 (IL 3) is produced by T lymphocytes and T cell lines, as well as by a myelomonocytic cell line (WEHI-3), and it activates lymphocytes and mast cells, as well as macrophages. Recently we have demonstrated that astrocytes act as immune accessory cells through the secretion of interleukin 1 and the presentation of antigens to T lymphocytes. Here we show that cultured astrocytes from newborn mice release a 30,000 m.w. factor that induces the expression of 20-alpha-hydroxysteroid dehydrogenase in nu/nu spleen cells and the proliferation of the IL 3-dependent cell line 32DCL.
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32

Fakih, Muhammad Nur, Nuraedhi Apriyanto, and Toni Setiawan. "PENINGKATAN HASIL BELAJAR MENDIAGNOSIS KERUSAKAN SISTEM REM KONVENSIONAL MELALUI MODEL PEMBELAJARAN BERBASIS MASALAH (PROBLEM BASED LEARNING) DENGAN MEDIA VIDEO." Journal of Vocational Education and Automotive Technology 5, no. 1 (2023): 40. http://dx.doi.org/10.31331/joveat.v5i1.2606.

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Penelitian ini bertujuan untuk: 1) Untuk mengetahui peningkatan hasil belajar dengan pembelajaran berbasis masalah (PBL) dengan media video pada siswa kelas XII TKR SMK NU 1 Slawi, 2) Untuk mengetahui peningkatan keaktifan belajar dengan pembelajaran berbasis masalah (PBL) dengan media video pada siswa kelas XII TKR SMK NU 1 Slawi, 3) Untuk mengetahui bagaimana guru mengimplementasikan dengan model pembelajaran berbasis masalah (PBL) dengan media video pada siswa kelas XII TKR SMK NU 1 Slawi. Jenis penelitian ini adalah Penelitian Tindakan Kelas. Penelitian ini dilaksanakan dalam dua siklus. S
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Ito, Kazuhide, Koki Mitsumune, Kazuki Kuga, Nguyen L. Phuong, Kenji Tani, and Kiao Inthavong. "Prediction of convective heat transfer coefficients for the upper respiratory tracts of rat, dog, monkey, and humans." Indoor and Built Environment 26, no. 6 (2016): 828–40. http://dx.doi.org/10.1177/1420326x16662111.

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In vivo studies involving mammal surrogate models for toxicology studies have restrictions related to animal protection and ethics. Computer models, i.e., in silico models, have great potential to contribute towards essential understanding of heat and mass transfer phenomena in respiratory tracts in place of in vivo and in vitro studies. Here, we developed numerical upper airway models of a rat, a dog, a monkey, and two humans by using computed tomography data and then applied computational fluid dynamics analysis. Convective heat transfer coefficients were precisely analysed as a function of
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34

Oréa, Valérie, Roy Kanbar, Bruno Chapuis, Christian Barrès, and Claude Julien. "Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat." Journal of Applied Physiology 102, no. 3 (2007): 1034–40. http://dx.doi.org/10.1152/japplphysiol.01064.2006.

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This study examined the possible influence of changes in heart rate (HR) on the gain of the transfer function relating renal sympathetic nerve activity (RSNA) to arterial pressure (AP) at HR frequency in rats. In seven urethane-anesthetized rats, AP and RSNA were recorded under baseline conditions (spontaneous HR = 338 ± 6 beats/min, i.e., 5.6 ± 0.1 Hz) and during 70-s periods of cardiac pacing at 6–9 Hz applied in random order. Cardiac pacing slightly increased mean AP (0.8 ± 0.2 mmHg/Hz) and decreased pulse pressure (−3.6 ± 0.3 mmHg/Hz) while leaving the mean level of RSNA essentially unalte
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35

Robaglia, A., and R. Seite. "Changes in nucleoli and nucleolar fibrillar centres of chromaffin cells in rat adrenal medulla over a 24-hour period: an ultrastructural and stereological analysis." Journal of Cell Science 77, no. 1 (1985): 255–62. http://dx.doi.org/10.1242/jcs.77.1.255.

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A stereological and ultrastructural study was performed on the nucleoli of the adrenal medulla chromaffin cells of rats exposed to a standardized 12 h light/12 h dark cycle with free access to food and water. The animals were killed three at a time, every 4 h during the 24-h span and fixed by intracardiac perfusion. In these reticulated nucleoli, the stereological analysis over a 24-h period showed a variation dependent on the time of killing for the two parameters investigated, the mean nucleolar volume, Vnu, and the mean volume of the fibrillar centres, Vfc(nu). The minimal value occurred at
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36

McCormick, K. L., and G. J. Mick. "Kinetic superiority of intra- vs. extracellular pentose pathway flux: studies in porous adipocytes." American Journal of Physiology-Cell Physiology 261, no. 3 (1991): C476—C481. http://dx.doi.org/10.1152/ajpcell.1991.261.3.c476.

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Considering how the cytosol is typically prepared, to wit, by cell disruption and ultracentrifugation, historically this compartment has been deemed unstructured and kinetically analogous to a solubilized system. By prudently permeabilizing rat adipocytes so that there is scant enzyme egress, intermediary metabolism can be explored intracellularly. Herein, cytoplasmic flux vs. a soluble reference system was compared. The three-enzyme oxidative portion of the pentose pathway was examined using [1-14C]glucose 6-phosphate (G-6-P); both the steady-state velocities (nu o) and transient times (tau s
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37

Doss, Kishore Krishnagiri Manoj, Pei En Mion, Yu-Chieh Jill Kao, Tsung-Ter Kuo, and Jyh-Cheng Chen. "Performance Evaluation of a PET of 7T Bruker Micro-PET/MR Based on NEMA NU 4-2008 Standards." Electronics 11, no. 14 (2022): 2194. http://dx.doi.org/10.3390/electronics11142194.

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Purpose: This study aimed to measure the performance evaluation of the Bruker sequential micro-positron emission tomography/magnetic resonance imaging (PET/MRI) scanner by following National Electrical Manufacturers Association (NEMA) NU 4-2008 standards’ protocol. The system consists of a high-performance silicon photomultiplier (SiPM) advanced technology detector and a continuous lutetium-yttrium oxyorthosilicate (LYSO) crystal. Methods: A 22Na (sodium-22) point source was utilized to assess the spatial resolution and system sensitivity, and the Micro-PET scatter phantom measurements were co
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38

Muralidhar, Sumitra, Anne M. Pumfery, Morad Hassani, et al. "Identification of Kaposin (Open Reading Frame K12) as a Human Herpesvirus 8 (Kaposi’s Sarcoma-Associated Herpesvirus) Transforming Gene." Journal of Virology 72, no. 6 (1998): 4980–88. http://dx.doi.org/10.1128/jvi.72.6.4980-4988.1998.

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ABSTRACT The recently identified human herpesvirus 8 (HHV-8, or Kaposi’s sarcoma-associated herpesvirus) has been implicated in the etiology of both Kaposi’s sarcoma (KS) and primary effusion (body cavity-based) lymphoma (PEL) (Y. Chang et al., Science 266:1865–1869, 1994; P. S. Moore et al., J. Virol. 70:549–558, 1996). An important feature of the association of HHV-8 with these malignancies is the expression of an abundant, latency-associated 0.7-kb transcript, T0.7 (W. Zhong et al., Proc. Natl. Acad. Sci. USA 93:6641–6646, 1996). T0.7 is found in all stages in nearly all KS tumors of differ
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39

Cartier, N., R. Lacave, V. Vallet, et al. "Establishment of renal proximal tubule cell lines by targeted oncogenesis in transgenic mice using the L-pyruvate kinase-SV40 (T) antigen hybrid gene." Journal of Cell Science 104, no. 3 (1993): 695–704. http://dx.doi.org/10.1242/jcs.104.3.695.

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Targeted oncogenesis allowed us to obtain two cell lines which have been derived from the proximal tubule of kidney from transgenic mice harbouring the simian virus (SV40) large T and small t antigens placed under the control of the 5′ regulatory sequence from the rat L-type pyruvate kinase (L-PK) gene. The cell lines (PKSV-PCT and PKSV-PR cells) were derived from early (PCT) and late (Pars Recta, PR) microdissected proximal tubules grown in D-glucose-enriched medium. In such conditions of culture, both cell lines exhibited L-PK transcripts, a stable expression of SV40-encoded nuclear large T
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40

Chaouad, B., E. Moudilou, A. Ghoul, et al. "Implication de la balance MMP-2/TIMP-2 et MMP-9/TIMP-1 dans le remodelage matriciel myocardique chez le rat des sables, Psammomys obesus hyperhomocystéinémique." Nutrition Clinique et Métabolisme 37, no. 2 (2023): e76. http://dx.doi.org/10.1016/j.nupar.2023.03.139.

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41

GUILLAUMOT, Patricia, I. SABBAGH, J. BERTRAND, and Hélène COHEN. "Absence d'augmentation des récepteurs de la prolactine le jour de l'œstrus dans la glande mammaire de rat nu IPL." Reproduction Nutrition Développement 26, no. 2B (1986): 543–49. http://dx.doi.org/10.1051/rnd:19860402.

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42

Sarwar, Ghulam, Robert Blair, Mendel Friedman, et al. "Comparison of Interlaboratory Variation in Amino Acid Analysis and Rat Growth Assays for Evaluating Protein Quality." Journal of AOAC INTERNATIONAL 68, no. 1 (1985): 52–56. http://dx.doi.org/10.1093/jaoac/68.1.52.

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Abstract Estimates of inter- and intralaboratory variation of protein efficiency ratio (PER), relative PER (RPER), net protein ratio (NPR), relative NPR (RNPR), and nitrogen utilization (NU) were compared with those of amino acid analysis in the same batches of 7 protein sources (ANRC casein, egg white solids, minced beef, soy assay protein, rapeseed protein concentrate, pea flour, and whole wheat flour). Interlaboratory variation (estimated as between-laboratories coefficients of variation, CV) of NPR and RNPR (up to 6.0%) was lower than that of PER (up to 20.2%) and RPER (up to 18.5%). The i
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43

Kwon, T., B. Lee, E. Yoo, S. Chung, Y. Park, and B. Kim. "Targeting bladder tumor cells in vivo and in the urine by a peptide identified using phage display." Journal of Clinical Oncology 24, no. 18_suppl (2006): 10071. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.10071.

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10071 Background: Bladder cancer is one of the most common tumors of genitourinary tract. Selective delivery of drugs to tumor tissues is important for effective tumor therapy. Here we identified a peptide targeting bladder tumor cells using phage display. Methods: Phage peptide library containing CX7C (C-cysteine and X-any amino acid residue) was based on T7 415–1b phage vector (Novagen). Tumor xenografts were prepared by subcutaneously injecting BALB/c Nu/nu female nude mice with HT-1376 bladder tumor cells. For a carcinogen-induced tumor model, Fischer 344 female rats were supplied ad libit
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44

Disselhorst, Jonathan A., Danny F. Newport, Andreas M. Schmid, et al. "NEMA NU 4-2008 performance evaluation and MR compatibility tests of an APD-based small animal PET-insert for simultaneous PET/MR imaging." Physics in Medicine & Biology 67, no. 4 (2022): 045015. http://dx.doi.org/10.1088/1361-6560/ac499d.

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Abstract An avalanche photodiode (APD)-based small animal positron emission tomography (PET)-insert was fully evaluated for its PET performance, as well as potential influences on magnetic resonance imaging (MRI) performance. This PET-insert has an extended axial field of view (FOV) compared with the previous design to increase system sensitivity, as well as an updated cooling and temperature regulation to enable stable and reproducible PET acquisitions. The PET performance was evaluated according to the National Electrical Manufacturers Association NU4-2008 protocol. The energy and timing res
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45

Mosquera-Sulbarán, Jesús, Adriana Pedreáñez, Yenddy Carrero, and Catherina Peña. "Nuclear and cytoplasmic expressions of the receptor for advanced glycation end products (RAGE) in the rat central nervous system." Investigación Clínica 64, no. 4 (2023): 505–12. http://dx.doi.org/10.54817/ic.v64n4a07.

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The receptor for advanced glycation end products (RAGE) is a transmembrane protein involved in the induction of inflammatory processes and oxidative stress after interacting with its ligands on the cell surface. Lo-calization on the cell surface is necessary for interaction with the ligands. This study aimed to determine the expression of RAGE in different parts of the nor-mal rat brain and cerebellum using the immunofluorescence technique. Sev-eralcerebral cortex layers (molecular/granular layers: M/GL; pyramidal layer: PL) and the hypothalamus were analyzed, as well as the molecular layer (C
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46

Medlock, E. S., I. Goldschneider, D. L. Greiner, and L. Shultz. "Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. II. Description of a microenvironmental defect for the generation of terminal deoxynucleotidyltransferase-positive bone marrow cells in vitro." Journal of Immunology 138, no. 11 (1987): 3590–97. http://dx.doi.org/10.4049/jimmunol.138.11.3590.

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Abstract We have presented evidence in a previous paper that the development of prothymocytes, pre-B cells, and TdT+ lymphoid precursor cells in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mice is defective. In the present study, we have used a selective culture system that supports the generation of rat- and mouse-origin TdT+ bone marrow lymphoid cells in vitro to further investigate the early stages of lymphopoiesis in me/me and mev/mev mice. The results demonstrate that bone marrow stromal cell feeder layers derived from me/me and mev/mev mice do not support the grow
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47

Mulyati, Mulyati, Susy Wijayanti, Annisa Nur Islahi, Anindyanari Rahma Sriyekti Saraswati, Ashfiya Hanif Hasnadewi, and Safira Ratri Dwi Setyasari. "Metal Bioaccumulation in Albino Rat Tissues Treated with Decontaminated Sea Lettuce (<i>Ulva lactuca</i> L.)." Journal of Tropical Biodiversity and Biotechnology 9, no. 2 (2024): 84533. http://dx.doi.org/10.22146/jtbb.84533.

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Ulva lactuca is a macroalgae that contains high nutritional values. The heavy metal contaminants in natural Ulva lactuca needs to be eliminated or decreased using natural agent. The aim of this research was to determine the bioaccumulation of Pb, Cd, Hg, and the impact on liver and gastrointestinal function. Parameters of this research were Hepatosomatic Index (HSI), SGPT levels, SGOT levels, bioaccumulation Pb, Cd, Hg, and histological structure of liver and small intestine. Besides that, the progression of body weight was observed. Twelve female Wistar rats (Rattus norvegicus Berkenhout, 176
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48

Thomas, L., and H. Betz. "Synaptophysin binds to physophilin, a putative synaptic plasma membrane protein." Journal of Cell Biology 111, no. 5 (1990): 2041–52. http://dx.doi.org/10.1083/jcb.111.5.2041.

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We have developed procedures for detecting synaptic vesicle-binding proteins by using glutaraldehyde-fixed or native vesicle fractions as absorbent matrices. Both adsorbents identify a prominent synaptic vesicle-binding protein of 36 kD in rat brain synaptosomes and mouse brain primary cultures. The binding of this protein to synaptic vesicles is competed by synaptophysin, a major integral membrane protein of synaptic vesicles, with half-maximal inhibition seen between 10(-8) and 10(-7) M synaptophysin. Because of its affinity for synaptophysin, we named the 36-kD synaptic vesicle-binding prot
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49

Liu, Zhendong, Ruotian Zhang, Xin Chen, et al. "Identification of hub genes and small-molecule compounds related to intracerebral hemorrhage with bioinformatics analysis." PeerJ 7 (October 25, 2019): e7782. http://dx.doi.org/10.7717/peerj.7782.

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Background Because of the complex mechanisms of injury, conventional surgical treatment and early blood pressure control does not significantly reduce mortality or improve patient prognosis in cases of intracerebral hemorrhage (ICH). We aimed to identify the hub genes associated with intracerebral hemorrhage, to act as therapeutic targets, and to identify potential small-molecule compounds for treating ICH. Methods The GSE24265 dataset, consisting of data from four perihematomal brain tissues and seven contralateral brain tissues, was downloaded from the Gene Expression Omnibus (GEO) database
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50

Giraldo, Esther, Pablo Bonilla, Mara Mellado, et al. "Transplantation of Human-Fetal-Spinal-Cord-Derived NPCs Primed with a Polyglutamate-Conjugated Rho/Rock Inhibitor in Acute Spinal Cord Injury." Cells 11, no. 20 (2022): 3304. http://dx.doi.org/10.3390/cells11203304.

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Neural precursor cell (NPC) transplantation represents a promising therapy for treating spinal cord injuries (SCIs); however, despite successful results obtained in preclinical models, the clinical translation of this approach remains challenging due, in part, to the lack of consensus on an optimal cell source for human neuronal cells. Depending on the cell source, additional limitations to NPC-based therapies include high tumorigenic potential, alongside poor graft survival and engraftment into host spinal tissue. We previously demonstrated that NPCs derived from rat fetal spinal cords primed
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