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1

Xie, Qingyi, Chunfeng Ma, Guangzhao Zhang, and Christine Bressy. "Poly(ester)–poly(silyl methacrylate) copolymers: synthesis and hydrolytic degradation kinetics." Polymer Chemistry 9, no. 12 (2018): 1448–54. http://dx.doi.org/10.1039/c8py00052b.

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2

Folini, Jenny, Chao-Hung Huang, James C. Anderson, Wolfgang P. Meier, and Jens Gaitzsch. "Novel monomers in radical ring-opening polymerisation for biodegradable and pH responsive nanoparticles." Polymer Chemistry 10, no. 39 (2019): 5285–88. http://dx.doi.org/10.1039/c9py01103j.

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We report the first amine-bearing cyclic ketene acetals (CKAs) for radical ring-opening polymerisation (RROP). The resulting polyesters and their corresponding nanoparticles were biodegradable and showed the desired pH sensitive behaviour.
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3

Lin, Si-Ting, Chung-Chi Wang, Chi-Jung Chang, Yasuyuki Nakamura, Kun-Yi Andrew Lin, and Chih-Feng Huang. "Progress in the Preparation of Functional and (Bio)Degradable Polymers via Living Polymerizations." International Journal of Molecular Sciences 21, no. 24 (2020): 9581. http://dx.doi.org/10.3390/ijms21249581.

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This review presents the latest developments in (bio)degradable approaches and functional aliphatic polyesters and polycarbonates prepared by typical ring-opening polymerization (ROP) of lactones and trimethylene carbonates. It also considers several recent innovative synthetic methods including radical ring-opening polymerization (RROP), atom transfer radical polyaddition (ATRPA), and simultaneous chain- and step-growth radical polymerization (SCSRP) that produce aliphatic polyesters. With regard to (bio)degradable approaches, we have summarized several representative cleavable linkages that
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4

Singha, Nikhil Kumar, Amalin Kavitha, Prodip Sarker, and Stephen Rimmer. "Copper-mediated controlled radical ring-opening polymerization (RROP) of a vinylcycloalkane." Chemical Communications, no. 26 (2008): 3049. http://dx.doi.org/10.1039/b801149d.

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5

Jackson, Alexander W., Srinivasa Reddy Mothe, Lohitha Rao Chennamaneni, Alexander van Herk, and Praveen Thoniyot. "Unraveling the History and Revisiting the Synthesis of Degradable Polystyrene Analogues via Radical Ring-Opening Copolymerization with Cyclic Ketene Acetals." Materials 13, no. 10 (2020): 2325. http://dx.doi.org/10.3390/ma13102325.

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Degradable analogues of polystyrene are synthesized via radical ring-opening (co)polymerization (rROP) between styrene and two cyclic ketene acetals, namely 2-methylene-1,3-dioxepane (MDO) and 5,6-benzo-2-methylene-1,3-dioxepane (BMDO). This approach periodically inserts ester bonds throughout the main chain of polystyrene, imparting a degradation pathway via ester hydrolysis. We discuss the historical record of this approach, with careful attention paid to the conflicting findings previously reported. We have found a common 1H NMR characterization error, repeated throughout the existing body
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6

Dishop, Megan K. "Robbins Review of Pathology." Archives of Pathology & Laboratory Medicine 125, no. 3 (2001): 456–57. http://dx.doi.org/10.5858/2001-125-456b-rrop.

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7

Popović, Zoran B., Kent A. Mowrey, Youhua Zhang, et al. "Slow rate during AF improves ventricular performance by reducing sensitivity to cycle length irregularity." American Journal of Physiology-Heart and Circulatory Physiology 283, no. 6 (2002): H2706—H2713. http://dx.doi.org/10.1152/ajpheart.00571.2002.

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Atrial fibrillation (AF) is characterized by short and irregular ventricular cycle lengths (VCL). While the beneficial effects of heart rate slowing (i.e., the prolongation of VCL) in AF are well recognized, little is known about the impact of irregularity. In 10 anesthetized dogs, R-R intervals, left ventricular (LV) pressure, and aortic flow were collected for >500 beats during fast AF and when the average VCL was prolonged to 75%, 100%, and 125% of the intrinsic sinus cycle length by selective atrioventricular (AV) nodal vagal stimulation. We used the ratio of the preceding and prepreced
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8

Reddy Mothe, Srinivasa, Jacqueline S. J. Tan, Lohitha R. Chennamaneni, et al. "A systematic investigation of the ring size effects on the free radical ring‐opening polymerization ( rROP ) of cyclic ketene acetal ( CKA ) using both experimental and theoretical approach." Journal of Polymer Science 58, no. 12 (2020): 1728–38. http://dx.doi.org/10.1002/pol.20200210.

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9

Garnett, Holly Ann. "Referendum Resource Officers in the 2007 Ontario Referendum on Electoral Reform." Canadian Political Science Review 8, no. 1 (2014): 63–84. http://dx.doi.org/10.24124/c677/2014387.

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On October 10th, 2007, Ontarians overwhelmingly rejected a proposed change to their electoral system in a province-wide referendum on a new mixed-member proportional (MMP) system. Many commentators and academics blamed this failure of MMP on the quality of Election Ontario’s public education campaign, which was comprised of advertisements, an information hotline, a website, and public outreach activities. Elections Ontario’s public outreach element contained a unique program of grassroots education through local liaison officers. Elections Ontario chose to hire one Referendum Resource Officer
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10

Onders, Richard J., Steven D. Mims, Changzheng Wang, and William D. Pearson. "Reservoir Ranching of Paddlefish." North American Journal of Aquaculture 63, no. 3 (2001): 179–90. http://dx.doi.org/10.1577/1548-8454(2001)063<0179:rrop>2.0.co;2.

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11

Li, Chao, Hengyi Li, Xiong Fu, Qiang Huang, and Yinghua Li. "Purification, Characterization, and Anti-Inflammatory Potential of Free and Bound Polyphenols Extracted from Rosa roxburghii Tratt Pomace." Foods 13, no. 13 (2024): 2044. http://dx.doi.org/10.3390/foods13132044.

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Rosa roxburghii Tratt pomace (RRTP), an underutilized byproduct, is rich in polyphenol compounds. This study aimed to further explore the purification, characterization, anti-inflammatory activities, and underlying molecular mechanisms of free polyphenols (RRTP-FP) and bound polyphenols (RRTP-BP) from RRTP. The results indicated that AB-8 macroporous resin emerged as the preferred choice for subsequent separation and purification. The purities of purified RRTP-FP (P-RRTP-FP) and purified RRTP-BP (P-RRTP-BP) increased by 103.34% and 66.01%, respectively. Quantitative analysis identified epigall
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12

Day, Stephanie L., and Carol McDonald Connor. "Examining the Relations Between Self-Regulation and Achievement in Third-Grade Students." Assessment for Effective Intervention 42, no. 2 (2016): 97–109. http://dx.doi.org/10.1177/1534508416670367.

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Children with stronger self-regulation skills generally demonstrate greater overall success in school both academically and socially. However, there are few valid and reliable measures of self-regulation in middle elementary school. Such a measure could help identify whether a child is truly having difficulties. Thus, the Remembering Rules and Regulation Picture Task (RRRP) was developed. The aim of this study was to develop scoring systems for the RRRP and then to examine the associations between RRRP and independent measures of self-regulation and academic achievement in mathematics and read
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13

Sbergio, Stefanie-Grace, Peter Liang, Greg Beilhartz, et al. "EXTH-47. TUMOUR-TARGETED PAN-RAS INHIBITION AS A NOVEL THERAPY FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)." Neuro-Oncology 25, Supplement_5 (2023): v235. http://dx.doi.org/10.1093/neuonc/noad179.0900.

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Abstract INTRODUCTION Diffuse Intrinsic Pontine Glioma (DIPG) has a median survival of 9 months following diagnosis in children 7-9 years old. Current therapeutic options are limited to radiation and thus tumour specific vulnerabilities are the subject of ongoing research. One such vulnerability is RAS signalling due to its upregulation in DIPG. RAS regulates cellular proliferation and survival making it an attractive target. Based on diphtheria toxin (DT), we have developed a molecular chimera which selectively binds a DIPG cell surface receptor and releases a RAS cleaving peptidase (RRSP). W
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14

Ogilvie, Richard Ian, and Danuta Zborowska-Sluis. "Vascular capacitance and cardiac output in pacing-induced canine models of acute and chronic heart failure." Canadian Journal of Physiology and Pharmacology 73, no. 11 (1995): 1641–50. http://dx.doi.org/10.1139/y95-726.

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The relationship between stressed and total blood volume, total vascular capacitance, central blood volume, cardiac output (CO), and pulmonary capillary wedge pressure (Ppcw) was investigated in pacing-induced acute and chronic heart failure. Acute heart failure was induced in anesthetized splenectomized dogs by a volume load (20 mL/kg over 10 min) during rapid right ventricular pacing at 250 beats/min (RRVP) for 60 min. Chronic heart failure was induced by continuous RRVP for 2–6 weeks (average 24 ± 2 days). Total vascular compliance and capacitance were calculated from the mean circulatory f
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15

Vidimar, Vania, Minyoung Park, Caleb K. Stubbs, et al. "Proteolytic pan-RAS Cleavage Leads to Tumor Regression in Patient-derived Pancreatic Cancer Xenografts." Molecular Cancer Therapeutics 21, no. 5 (2022): 810–20. http://dx.doi.org/10.1158/1535-7163.mct-21-0550.

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Abstract The lack of effective RAS inhibition represents a major unmet medical need in the treatment of pancreatic ductal adenocarcinoma (PDAC). Here, we investigate the anticancer activity of RRSP-DTB, an engineered biologic that cleaves the Switch I of all RAS isoforms, in KRAS-mutant PDAC cell lines and patient-derived xenografts (PDX). We first demonstrate that RRSP-DTB effectively engages RAS and impacts downstream ERK signaling in multiple KRAS-mutant PDAC cell lines inhibiting cell proliferation at picomolar concentrations. We next tested RRSP-DTB in immunodeficient mice bearing KRAS-mu
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16

Seeliger, E., W. Boemke, M. Corea, T. Encke, and H. W. Reinhardt. "Mechanisms compensating Na and water retention induced by long-term reduction of renal perfusion pressure." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 273, no. 2 (1997): R646—R654. http://dx.doi.org/10.1152/ajpregu.1997.273.2.r646.

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Endogenous downregulation of plasma aldosterone (Aldo) concentration, despite increased plasma renin activity (PRA), has been suggested to compensate Na and water retention, which is induced by long-term reduction of renal perfusion pressure (rRPP). To determine whether fixed plasma Aldo concentration would prevent equilibration of 24-h Na and water balances during rRPP, chronically instrumented, freely moving beagle dogs were kept under standardized conditions (daily intake 5.5 mmol Na/kg body wt) and studied for 4 consecutive days under the following conditions: control without rRPP (protoco
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17

Davenport, Paul W., Pei-Ying Sarah Chan, Weirong Zhang, and Yang-Ling Chou. "Detection threshold for inspiratory resistive loads and respiratory-related evoked potentials." Journal of Applied Physiology 102, no. 1 (2007): 276–85. http://dx.doi.org/10.1152/japplphysiol.01436.2005.

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The relationship between detection threshold of inspiratory resistive loads and the peaks of the respiratory-related evoked potential (RREP) is unknown. It was hypothesized that the short-latency and long-latency peaks of the RREP would only be elicited by inspiratory loads that exceeded the detection threshold. The detection threshold for inspiratory resistive loads was measured in healthy subjects with inspiratory-interruption or onset load presentations. In a separate protocol, the RREPs were recorded with resistive loads that spanned the detection threshold. The loads were presented in sti
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18

Reinhardt, H. W., M. Corea, W. Boemke, et al. "Resetting of 24-h sodium and water balance during 4 days of servo-controlled reduction of renal perfusion pressure." American Journal of Physiology-Heart and Circulatory Physiology 266, no. 2 (1994): H650—H657. http://dx.doi.org/10.1152/ajpheart.1994.266.2.h650.

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This study examines whether an increase in renal perfusion pressure (RPP) is necessary to escape endogenously stimulated Na- and water-retaining mechanisms. In seven dogs stimulation was accomplished by a servo-controlled reduction of RPP (rRPP) below the threshold for pressure-dependent renin release for 4 days. Oral intake was standardized. Plasma renin activity (PRA) rose from 2.5 in controls to approximately 5 ng ANG I.ml-1 x h-1 during rRPP days. Plasma aldosterone concentration (PAC) increased by approximately 50% only on day 1 of rRPP but fell at or below control levels thereafter. The
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19

Morelli, Eugenio, Mariateresa Fulciniti, Mehmet K. Samur, et al. "RNA Regulator of Lipogenesis (RROL) Is a Novel Lncrna Mediating Protein-Protein Interaction at Gene Regulatory Loci Driving Lipogenic Programs in Multiple Myeloma." Blood 136, Supplement 1 (2020): 20–21. http://dx.doi.org/10.1182/blood-2020-142514.

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Long noncoding RNA (lncRNAs) are key epigenetic factors that drive the origin and progression of human cancers via mechanisms that are largely unknown. We have previuosly reported the clinical significance of a lncRNA signature in multiple myeloma (MM) as independent risk predictor for clinical outcome; and recently identified a lncRNA RROL (RNA Regulator of Lipogenesis) with impact on MM cell proliferation. Here we describe a unique regulatory function for RROL in the control of gene networks involved in the de novo lipogenesis (DNL) pathway, ultimately impacting MM cell growth and survival.
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20

Huang, Chien Hui, A. Daniel Martin, and Paul W. Davenport. "Effect of inspiratory muscle strength training on inspiratory motor drive and RREP early peak components." Journal of Applied Physiology 94, no. 2 (2003): 462–68. http://dx.doi.org/10.1152/japplphysiol.00364.2002.

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This study investigated the effect of inspiratory muscle strength training (IMST) on inspiratory motor drive [mouth occlusion pressure at 0.1 s (P0.1)] and respiratory-related evoked potentials (RREP). It was hypothesized that, if IMST increased inspiratory muscle strength, inspiratory motor drive would decrease. If motor drive were related to the RREP, it was further hypothesized that an IMST-related decrease in drive would change RREP latency and/or amplitude. Twenty-three subjects received IMST at 75% of their maximal inspiratory pressure (Pi max) with the use of a pressure threshold valve.
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21

Lin, Hota Chia-Sheng, Chia-Ling Huang, and Wei-Chang Yeh. "A Novel Constraints Model of Credibility-Fuzzy for Reliability Redundancy Allocation Problem by Simplified Swarm Optimization." Applied Sciences 11, no. 22 (2021): 10765. http://dx.doi.org/10.3390/app112210765.

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A novel constraints model of credibility-fuzzy for the reliability redundancy allocation problem (RRAP) is studied in this work. The RRAP that must simultaneously decide reliability and redundancy of components is an effective approach in improving the system reliability. In practice various systems, the uncertainty condition of components used in the systems, which few studies have noticed this state over the years, is a concrete fact due to several reasons such as production conditions, different batches of raw materials, time reasons, and climatic factors. Therefore, this study adopts the f
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22

Knafelc, Marie, and Paul W. Davenport. "Relationship between magnitude estimation of resistive loads, inspiratory pressures, and the RREP P1 peak." Journal of Applied Physiology 87, no. 2 (1999): 516–22. http://dx.doi.org/10.1152/jappl.1999.87.2.516.

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This study investigated the relationship among resistive load magnitude (ΔR), the cortical evoked potential P1peak amplitude of the respiratory-related evoked potential (RREP), mouth pressure (Pm), esophageal pressure (Pes), transdiaphragmatic pressure (Pdi), and resistive load magnitude estimation (ME) in human subjects. The RREP, Pdi, Pes, Pm, and ME were recorded in response to three ΔR values. The RREP was recorded from C3 and C4, referenced to the vertex CZ. The group means of the Pdi, Pm, ME, and RREP P1 amplitude increased with increases in the ΔR. A log-log plot of the P1 amplitudes sh
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23

Chou, Yang Ling, and Paul W. Davenport. "The effect of increased background resistance on the resistive load threshold for eliciting the respiratory-related evoked potential." Journal of Applied Physiology 103, no. 6 (2007): 2012–17. http://dx.doi.org/10.1152/japplphysiol.01232.2006.

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The detection threshold (ΔR50) of resistive (R) loads is a function of the total background resistance (R0). Increased R0 increases the ΔR50, but the ratio ΔR50/R0 remains constant. The respiratory-related evoked potential (RREP) is elicited only by R loads greater than the cognitive detection threshold, ΔR50. We hypothesized that the RREP Nf, P1, and N1 peaks will be elicited only when the added load ΔR/R0 is greater than the normal detection threshold, ΔR50/R0 = 0.30. We also hypothesized that when the R0 is increased by adding extrinsic R, the RREP will not be elicited if the ΔR/R0 is less
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24

de Verneuil, Maylis. "L’apatridie rrom en Europe." Plein droit 128, no. 1 (2021): 11–14. http://dx.doi.org/10.3917/pld.128.0013.

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25

Macre, Miriam de Souza, Márcio Pires, Luciana Regina Meireles, Sérgio O. Angel, and Heitor Franco de Andrade Jr. "Serology using rROP2 antigen in the diagnostic of toxoplasmosis in pregnant women." Revista do Instituto de Medicina Tropical de São Paulo 51, no. 5 (2009): 283–88. http://dx.doi.org/10.1590/s0036-46652009000500009.

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Toxoplasma gondii causes severe fetal disease during acute infection in pregnant women, thus demanding early diagnosis for effective treatment and fetus preservation. Fetal tests are inefficient and risky, and diagnosis is based on maternal IgM serology, which had weak screening ability due to increased sensitivity, with alternative IgG avidity tests. Here, we performed ELISA and avidity assays using a recombinant T. gondii antigen, rROP2, in samples from 160 pregnant women screened from a large public hospital who were referred due to positive IgM assays. IgG serology and avidity assays were
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26

Martin, Valentina, Alicia Supanitsky, Pablo C. Echeverria, et al. "Recombinant GRA4 or ROP2 Protein Combined with Alum or the gra4 Gene Provides Partial Protection in Chronic Murine Models of Toxoplasmosis." Clinical Diagnostic Laboratory Immunology 11, no. 4 (2004): 704–10. http://dx.doi.org/10.1128/cdli.11.4.704-710.2004.

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ABSTRACT The efficacy of vaccination with Toxoplasma gondii recombinant GRA4 (rGRA4) and ROP2 (rRPO2) proteins and a mix of both combined with alum were evaluated in C57BL/6 and C3H mice. In C57BL/6 mice, rGRA4 and rGRA4-rROP2 immunizations generated similar levels of immunoglobulin G1 (IgG1) and IgG2a isotypes against GRA4, whereas immunizations with rROP2 and the mix induced a predominant IgG1 production against ROP2. All groups of C3H vaccinated mice exhibited higher levels of IgG1 than IgG2a. rGRA4-stimulated splenocytes from vaccinated mice produced primarily gamma interferon while those
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27

Kim, Chang-Hyun, Hyung-Chul Nam, and Soon-Man Kwon. "Pitting Life for RRP System." Transactions of the Korean Society of Mechanical Engineers A 36, no. 4 (2012): 387–93. http://dx.doi.org/10.3795/ksme-a.2012.36.4.387.

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28

Xiong, Jin, Jie Tang, Penghua Guo, and Jingyin Li. "Flow Capacity Optimization of a Squirrel Cage Fan with a New Rounded Rectangle Volute under Size Limitation." Machines 11, no. 2 (2023): 283. http://dx.doi.org/10.3390/machines11020283.

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Squirrel cage fans (SCFs) are widely used in a variety of household appliances. Due to the restriction on installation size, the design of high-efficiency SCFs with high flow capacities is an important topic. In this study, we proposed a novel rounded rectangle volute profile (RRVP) for the design of compact high-flow SCFs. At first, we used computational fluid dynamics (CFD) to simulate the aerodynamic performances of three SCFs having the same impeller but different volutes, which were the common logarithmic-spiral volute profile, the cutting volute profile, and the RRVP volute at the maximu
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29

Chan, Pei-Ying Sarah, and Paul W. Davenport. "Respiratory-related evoked potential measures of respiratory sensory gating." Journal of Applied Physiology 105, no. 4 (2008): 1106–13. http://dx.doi.org/10.1152/japplphysiol.90722.2008.

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The purpose of this study was to demonstrate a neural respiratory gating system using a paired stimuli paradigm. The N1 peak of the respiratory-related evoked potential (RREP) represents early perceptual processing of respiratory sensory information. This is similar to the N100 peak shown with tactile sensation, where the second peak amplitude (S2) of the N100 peak from the somatosensory evoked potential (SEP) was smaller than the first peak amplitude (S1) when the stimuli were presented 500 ms apart. We hypothesized that paired inspiratory occlusions would result in a reduced amplitude of the
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30

López-Fernández, Josu, Juan J. Barrero, M. Dolors Benaiges, and Francisco Valero. "Truncated Prosequence of Rhizopus oryzae Lipase: Key Factor for Production Improvement and Biocatalyst Stability." Catalysts 9, no. 11 (2019): 961. http://dx.doi.org/10.3390/catal9110961.

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Recombinant Rhizopus oryzae lipase (mature sequence, rROL) was modified by adding to its N-terminal 28 additional amino acids from the C-terminal of the prosequence (proROL) to obtain a biocatalyst more suitable for the biodiesel industry. Both enzymes were expressed in Pichia pastoris and compared in terms of production bioprocess parameters, biochemical properties, and stability. Growth kinetics, production, and yields were better for proROL harboring strain than rROL one in batch cultures. When different fed-batch strategies were applied, lipase production and volumetric productivity of pro
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31

Machalska, Ewa, Grzegorz Zajac, Monika Halat, Aleksandra J. Wierzba, Dorota Gryko, and Malgorzata Baranska. "Resonance Raman Optical Activity Spectroscopy in Probing Structural Changes Invisible to Circular Dichroism Spectroscopy: A Study on Truncated Vitamin B12 Derivatives." Molecules 25, no. 19 (2020): 4386. http://dx.doi.org/10.3390/molecules25194386.

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This work demonstrates resonance Raman optical activity (RROA) spectra of three truncated vitamin B12 derivatives modified within the nucleotide loop. Since truncated cobalamins possess sufficiently high rotational strength in the range of ROA excitation (532 nm), it was possible to record their spectra in the resonance condition. They showed several distinct spectral features allowing for the distinguishing of studied compounds, in contrast to other methods, i.e., UV-Vis absorption, electronic circular dichroism, and resonance Raman spectroscopy. The improved capacity of the RROA method is ba
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32

Novakovic, Daniel, Alan T. L. Cheng, Daron H. Cope, and Julia M. L. Brotherton. "Estimating the prevalence of and treatment patterns for juvenile onset recurrent respiratory papillomatosis in Australia pre-vaccination: a pilot study." Sexual Health 7, no. 3 (2010): 253. http://dx.doi.org/10.1071/sh09142.

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Background: Recurrent respiratory papillomatosis (RRP) causes serious morbidity. RRP in Australia may be eliminated in the near future following the implementation of a national vaccination program using a human papillomavirus (HPV) vaccine that protects against infection with HPV types 6 and 11, those responsible for RRP. Baseline data on RRP prevalence and disease burden in Australia are lacking. Methods: Three study methods were used to estimate the burden of juvenile onset RRP in Australia. We conducted a retrospective chart review of RRP cases treated at The Children’s Hospital at Westmea
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33

Webster, Kate E., and Ian M. Colrain. "Multichannel EEG analysis of respiratory evoked-potential components during wakefulness and NREM sleep." Journal of Applied Physiology 85, no. 5 (1998): 1727–35. http://dx.doi.org/10.1152/jappl.1998.85.5.1727.

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Airway occlusion in awake humans produces a somatosensory evoked response called the respiratory-related evoked potential (RREP). In the present study, 29 channel evoked-potential recordings were obtained from seven men who were exposed to 250-ms inspiratory airway occlusions during wakefulness, stage 1, stage 2, and slow-wave sleep. The RREP recorded during wakefulness was similar to previous reports, with the unique observation of an additional short-latency positive peak with a mean latency of 25 ms. Short-latency RREP components were maintained in non-rapid-eye-movement (NREM) sleep. The c
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34

Oliveira, Saulo Fernandes Melo de, Lúcia Inês Oliveira, and Manoel Costa. "Influência da resistência ao rolamento no desempenho de velocidade no rúgbi em cadeiras de rodas independente da classificação funcional." Journal of Physical Education 30, no. 1 (2018): 3001. http://dx.doi.org/10.4025/jphyeduc.v30i1.3001.

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Nosso objetivo foi verificar as possíveis associações entre o desempenho de velocidade e a resistência ao rolamento (RROL) em atletas de rúgbi em cadeiras de rodas. Dessa forma, 16 jogadores foram avaliados nos próprios locais de treinamento das equipes. Foram coletados o peso dos sujeitos e das cadeiras de rodas, a RROL por um procedimento de campo e a velocidade pelo protocolo de sprint de 20 metros. Os dados foram analisados por meio de procedimentos de correlação de Pearson, correlação parcial e regressão linear simples. Os resultados demonstraram que há uma correlação negativa e significa
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35

Jiang, Guo-Liang, Thierry C. Marcel, Fernando Martínez, and Rients E. Niks. "Relative Ratio of Mature Pustules: A Simple Method to Assess Partial Resistance of Barley to Puccinia hordei." Plant Disease 91, no. 3 (2007): 301–7. http://dx.doi.org/10.1094/pdis-91-3-0301.

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In plant breeding and germplasm evaluation, large-scale assessment of quantitative resistance is desirable, but feasible only if a simple and accurate measure is available. In several plant-pathogen systems, latent period (LP) is a parameter that is well correlated with the level of partial resistance observed in field trials. However, measuring LP or relative LP (RLP), i.e., relative to the reference accessions, is laborious. We investigated the value of relative ratio of mature pustules (RRMP, relative to the susceptible control) as a simple and rapid alternative to replace LP estimation in
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36

Kim, Eung Sun, and Myongsoo Chong. "The Anti-depressive Effect of Rehmanniae Radix Preparata via Anti-inflammatory Activity." Journal of Korean Medicine 43, no. 1 (2022): 99–111. http://dx.doi.org/10.13048/jkm.22009.

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Objectives: Rehmanniae Radix Preparata (RRP) has been used as a traditional remedy to treat gynecology and endocrine diseases. Recently, studies on antioxidant and anti-inflammatory effects of RRP have been reported, so it was judged that RRP extracts would have an anti-depressive effect.Methods: We investigated the anti-neuroinflammatory and anti-depressive effect of RRP on lipopolysaccharide (LPS)-induced depression and LPS-stimulated BV2 microglia. RRP inhibited the LPS-stimulated excessive release of nitrite in the BV2 cells. RRP also significantly inhibited the inflammatory cytokines such
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37

Flenga, Maria G., and Maria J. Favvata. "The Effect of Magnitude Mw and Distance Rrup on the Fragility Assessment of a Multistory RC Frame Due to Earthquake-Induced Structural Pounding." Buildings 13, no. 7 (2023): 1832. http://dx.doi.org/10.3390/buildings13071832.

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The effect of an intensity measure’s (IM’s) sufficiency property on the probabilistic assessment of reinforced concrete (RC) structures due to floor-to-floor structural pounding conditions is examined. In the first part of this investigation, efficiency and sufficiency properties of 23 scalar IMs are verified. Then, the magnitude Mw and the distance Rrup are examined as elements in a vector with an efficient scalar IM to evaluate whether they have any significant effect on the structural response. Subsequently, probabilistic seismic demand models (PSDMs) are developed using linear regression a
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38

Sims, Andrew, Kim Keltie, Emma Belilios, et al. "Our experience in developing and operating the Airway Intervention Registry for Recurrent Respiratory Papillomatosis (AIR-RRP): national data collection." NIHR Open Research 2 (February 24, 2022): 22. http://dx.doi.org/10.3310/nihropenres.13244.1.

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Recurrent respiratory papillomatosis (RRP) is characterised by benign wart-like growths in the respiratory tract caused by the human papillomavirus (HPV). These warts vary in size and grow quickly, causing voice changes and airway obstruction. Whilst the condition is rare, RRP is more common and aggressive in children. There is currently no curative treatment for HPV, therefore RRP is managed by maintaining a safe airway and a serviceable voice by repeated surgery to remove the growths. A lack of specific diagnostic codes prevents reliable case ascertainment of RRP from routine administrative
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39

Shimokawaji, Tadasuke, Shoko Narita, Tomoyuki Naito, et al. "Clinical characteristics of nivolumab-induced radiation recall pneumonitis in patients with non-small cell lung cancer: A multicenter real-world analysis of 669 patients." Journal of Clinical Oncology 38, no. 5_suppl (2020): 88. http://dx.doi.org/10.1200/jco.2020.38.5_suppl.88.

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88 Background: Immune checkpoint inhibitors can cause immune-related pneumonitis in lung cancer patients. Some of those patients with history of previous thoracic radiation therapy (TRT) are reported to show radiation recall pneumonitis (RRP) pattern. In this multicenter retrospective study, we analyzed the patient background and clinical characteristics of RRP. Methods: Medical records of non-small cell lung cancer patients, who received nivolumab between December 2015 and March 2017, were retrospectively reviewed. Incidence of pneumonitis, and incidence, risk factors and clinical characteris
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40

Biancucci, Marco, George Minasov, Avik Banerjee, et al. "The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling." Science Signaling 11, no. 550 (2018): eaat8335. http://dx.doi.org/10.1126/scisignal.aat8335.

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The Ras–extracellular signal–regulated kinase pathway is critical for controlling cell proliferation, and its aberrant activation drives the growth of various cancers. Because many pathogens produce toxins that inhibit Ras activity, efforts to develop effective Ras inhibitors to treat cancer could be informed by studies of Ras inhibition by pathogens.Vibrio vulnificuscauses fatal infections in a manner that depends on multifunctional autoprocessing repeats-in-toxin, a toxin that releases bacterial effector domains into host cells. One such domain is the Ras/Rap1-specific endopeptidase (RRSP),
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41

Skokov, O. I., O. H. Dyachenko, V. V. Volovschikova, and M. S. Khorolsky. "THE RUBBER REINFORCED SUPPORT PARTS FOR COMPLEITING DYNAMICS AND QUIESCENT LOADS OF BRIDGE CONSTRUCTIONS." Science and Transport Progress, no. 33 (August 25, 2010): 259–61. http://dx.doi.org/10.15802/stp2010/13358.

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The research of deformation characteristics of the rubber reinforced support parts (RRBP), which compensate static and dynamic loadings of elements of bridge constructions, is conducted. The technology for manufacturing RRBP using new materials is developed; their deformation characteristics are investigated with the purpose of determination of the predicted operation life.
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42

Chan, Pei-Ying Sarah, and P. W. Davenport. "The role of nicotine on respiratory sensory gating measured by respiratory-related evoked potentials." Journal of Applied Physiology 108, no. 3 (2010): 662–69. http://dx.doi.org/10.1152/japplphysiol.00798.2009.

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Respiratory perception can be altered by changes in emotional or psychological states. This may be due to affective (i.e., anxiety) modulation of respiratory sensory gating. Nicotine withdrawal induces elevated anxiety and decreased somatosensory gating. Respiratory sensory gating is evidenced by decreased amplitude of the respiratory-related evoked potentials (RREP) N1 peak for the second occlusion (S2) when two 150-ms occlusions are presented with a 500-ms interval during an inspiration. The N1 peak amplitude ratio of the S2 and first occlusion (S1) (S2/S1) is &lt;0.5 and due to central neur
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43

Stevens, Charles F., and James H. Williams. "Discharge of the Readily Releasable Pool With Action Potentials at Hippocampal Synapses." Journal of Neurophysiology 98, no. 6 (2007): 3221–29. http://dx.doi.org/10.1152/jn.00857.2007.

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A readily releasable pool (RRP) of synaptic vesicles has been identified at hippocampal synapses with application of hypertonic solution. RRP size correlates with important properties of synaptic function such as release probability. However, a discrepancy in RRP size has been reported depending on the method used to evoke synaptic release. This study was undertaken to determine quantitative relationships between the RRP defined with hypertonic solution and that released with trains of action potentials. We find that asynchronous release at cell culture synapses contributes significantly to th
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44

Durnez, Anne, Geert Vanderschueren, Luc Lateur, René Westhovens, and Patrick Verschueren. "Effectiveness of initial treatment allocation based on expert opinion for prevention of rapid radiographic progression in daily practice of an early RA cohort." Annals of the Rheumatic Diseases 70, no. 4 (2010): 634–37. http://dx.doi.org/10.1136/ard.2010.135319.

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ObjectivesTo evaluate expert treatment selection for early rheumatoid arthritis and to validate a prediction model for rapid radiographic progression (RRP) in daily practice.MethodsPatients received initial combination therapy with steroids (ICTS) or disease-modifying antirheumatic drug monotherapy (IMT) after informal evaluation of prognostic factors, followed by a tight control strategy. Changes in Sharp/van der Heijde score (total Sharp score (TSS)) of &gt;5 units over 1 year (=RRP) were documented. The mean change in TSS and proportion with RRP were compared between groups. Based on the 28
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45

Zhao, Weiying, A. Daniel Martin, and Paul W. Davenport. "Respiratory-related evoked potentials elicited by inspiratory occlusions in double-lung transplant recipients." Journal of Applied Physiology 93, no. 3 (2002): 894–902. http://dx.doi.org/10.1152/japplphysiol.01218.2001.

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This study investigated the role of lung vagal afferents in the respiratory-related evoked potential (RREP) response to inspiratory occlusions by using double-lung transplant recipients as a lung denervation model. Evoked potential recordings in response to inspiratory occlusions were obtained from 10 double-lung transplant (DLT) recipients with normal lung function and 12 healthy control (Nor) subjects under the attend, ignore, and unoccluded conditions. Results demonstrated that early-latency RREP components (P1, P1a, Nf, and N1) were not significantly different between the DLT and the Nor g
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46

Davenport, P. W., I. M. Colrain, and P. M. Hill. "Scalp topography of the short-latency components of the respiratory-related evoked potential in children." Journal of Applied Physiology 80, no. 5 (1996): 1785–91. http://dx.doi.org/10.1152/jappl.1996.80.5.1785.

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Respiratory-related evoked potentials (RREPs) have been elicited by inspiratory occlusion and recorded at electroencephalographic (EEG) sites overlying the somatosensory cortex in adults. The present study was the first to be conducted in normal children and was designed to identify the scalp distribution of the early RREP components. EEG responses to occlusion were recorded from CZ-C3, CZ-C4, and 17 sites referenced to the linked earlobes. The RREP was observed in all subjects in the CZ-C3 and CZ-C4 electrode pairs. The earlobe-referenced recordings revealed two RREP patterns. The P1 and N1 p
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47

Davenport, Paul W., and Alastair A. Hutchison. "Cerebral cortical respiratory-related evoked potentials elicited by inspiratory occlusion in lambs." Journal of Applied Physiology 93, no. 1 (2002): 31–36. http://dx.doi.org/10.1152/japplphysiol.00177.2001.

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Respiratory-related evoked potentials (RREP) elicited by inspiratory mechanical loads have been recorded in humans. Early RREP peaks were hypothesized to be generated by activation of neurons in the somatosensory cortex. An animal model was developed to test this hypothesis in chronically instrumented, awake, spontaneously breathing lambs. Electrocorticogram (ECoG) was recorded bilaterally with ball electrodes on the dural surface over the somatosensory region. Inspiratory occlusions were presented through a face mask or endotracheal tube as interruptions of inspiration. Occlusion-elicited evo
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48

Boemke, W., E. Seeliger, L. Rothermund, et al. "ACE inhibition prevents Na and water retention and MABP increase during reduction of renal perfusion pressure." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 269, no. 3 (1995): R481—R489. http://dx.doi.org/10.1152/ajpregu.1995.269.3.r481.

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Two groups of six dogs were studied during 4 control days and 4 days of reduced renal perfusion pressure (rRPP) servo controlled at 20% below the individual dog's 24-h mean arterial blood pressure (MABP) during control days, i.e., below the threshold for renin release. On rRPP days, endogenous activation of plasma aldosterone and angiotensin II was inhibited by the angiotensin-converting enzyme inhibitor captopril. The dogs were kept on a high-Na and high-water intake. Unlike studies during rRPP alone, there was no Na and water retention during rRPP+captopril. Glomerular filtration rate droppe
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49

Egido Piqueras, Marto. "Comunicación persuasiva como estrategia de neurocomunicación para las relaciones públicas." Miguel Hernández Communication Journal 14 (July 28, 2023): 339–60. http://dx.doi.org/10.21134/mhjournal.v14i.1961.

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El presente trabajo se enfoca en el estudio de la comunicación persuasiva como estrategia de neurocomunicación de gran utilidad para las Relaciones Públicas. La persuasión es una parte importante de la comunicación, en la que se busca influir en la opinión o comportamiento de un receptor, por lo que es posible considerarla como una estrategia que puede ser explicada desde la neurocomunicación para optimizar su aplicación en el ámbito de las RRPP. Así, el presente escrito tiene el objetivo de examinar cómo la comunicación persuasiva puede funcionar como estrategia efectiva en las RRPP para infl
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50

Ramaseshan, B., Jochen Wirtz, and Dominik Georgi. "The enhanced loyalty drivers of customers acquired through referral reward programs." Journal of Service Management 28, no. 4 (2017): 687–706. http://dx.doi.org/10.1108/josm-07-2016-0190.

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Purpose The purpose of this paper is to extend prior research on referral reward programs (RRPs) by examining if and how the mode of customer acquisition (RRP-acquired customers vs non-RRP-acquired new customers) moderates the relationships between customer satisfaction and attitudinal loyalty, perceived switching costs and attitudinal loyalty, and attitudinal loyalty and behavioral loyalty (i.e. recommendations, cross-buying, and total spend). Design/methodology/approach Set in a banking context, this study is the first in an RRP context to link survey data with actual purchase data from a ba
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