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Tesis sobre el tema "Scale-up"

Autor: Grafiati
Publicado: 4 de junio de 2021
Última modificación: 25 de julio de 2025

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1

Wiggenhorn, Michael. "Scale-Up of Liposome Manufacturing." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-84870.

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2

Mankosa, Michael James. "Scale-up of column flotation." Diss., This resource online, 1990. https://scholar.lib.vt.edu/ETD-db/ETD-catalog/manage_bound.

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3

Zauner, Rudolf. "Scale-up of precipitation processes." Thesis, University College London (University of London), 1999. http://discovery.ucl.ac.uk/1317927/.

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This thesis concerns the scale-up of precipitation processes aimed at predicting product particle characteristics. Although precipitation is widely used in the chemical and pharmaceutical industry, successful scale-up is difficult due to the absence of a validated methodology. It is found that none of the conventional scale-up criteria reported in the literature (equal power input per unit mass, equal tip speed, equal stirring rate) is capable of predicting the experimentally observed effects of the mixing conditions on kinetic rates and particle characteristics. As a result of high gradients
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4

Smith, Keith Buchanan. "Scale-up of oscillatory flow mixing." Thesis, University of Cambridge, 2000. https://www.repository.cam.ac.uk/handle/1810/238305.

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Oscillatory Flow Mixing is a recent development in mixing technology which has evolved over the past decade. It has a number of similarities to other mixing technologies, particularly pulsed and reciprocating plate columns, but at the laboratory scale has demonstrated a number of advantageous properties. These properties (such as control of residence time distribution, improved heat transfer and predictable mixing times) have been demonstrated at the laboratory scale for a wide range of different potential applications, but until now there has been a lack of firm understanding and research int
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5

Colby, Christopher Brett. "Optimisation of scale-up of chromatography /." Title page, table of contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phc686.pdf.

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6

Scholtzova, Angela. "Scale up and modelling of HPLC." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368109.

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7

Davis, Ryan Z. "Design and Scale-Up of Production Scale Stirred Tank Fermentors." DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/537.

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In the bio/pharmaceutical industry, fermentation is extremely important in pharmaceutical development, and in microbial research. However, new fermentor designs are needed to improve production and reduce costs of complex systems such as cultivation of mammalian cells and genetically engineered micro-organisms. Traditionally, stirred tank design is driven by the oxygen transfer capability needed to achieve cell growth. However, design methodologies available for stirred tank fermentors are insufficient and many times contain errors. The aim of this research is to improve the design of prod
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8

Coleman, Simon James. "Scale-up of enface electrochemical reactor systems." Thesis, University of Newcastle upon Tyne, 2015. http://hdl.handle.net/10443/3071.

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Photolithography, the standard pattern transfer technique, has many sustainable issues due to the application of a mask to the substrate. A ‘maskless’ pattern transfer method, called the Enface technique, has recently been proposed for metal plating and etching. This method introduces the idea of bringing a patterned tool and a substrate together in close proximity and a current or voltage is passed between them enabling metal to be selectively deposited or removed from the substrate. The process requires sufficient electrolyte agitation within a narrow inter-electrode gap and has previously b
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9

Heider, Patrick Louis. "Scale-up of continuous chemical synthesis systems." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/86870.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2013.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 72-80).<br>Continuous flow systems for chemical synthesis have become increasingly important in the pharmaceutical and fine chemical industry in the past decade. Initially, this work was confined primarily to microfluidic systems, but recently ther
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10

Eraydin, Mert Kerem. "Scale-up of Using Novel Dewatering Aids." Diss., Virginia Tech, 2009. http://hdl.handle.net/10919/27990.

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Coal preparation plants use large quantities of water for cleaning processes. Upon cleaning, the spent water must be removed such that the final product moisture level meets market constraints. However, removal of free water from the surface of fine particles is difficult and costly, and often the results are less than desirable. Fine particles inherently have very large surface areas, and hence retain large amounts of water. Increased amounts of fines also cause denser particle packing, which creates relatively small capillaries in filter cakes and, thus, cause slower dewatering kinetics. As
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11

Cai, Yusi. "Scale-up of Micro-structured Synthetic Paper." Thesis, KTH, Skolan för teknik och hälsa (STH), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-215107.

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12

Dueñas-Espín, Iván 1979. "Scale up of Integrated Care for Chronic Patients." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/482054.

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The current PhD thesis consists in a compilation of three papers aimed to analyze core drivers of Integrated care (IC) scale-up, namely: (i) assess the effects of anxiety and depression on physical activity in COPD patients as a use case of chronic patients; (ii) analyze health risk assessment strategies in the 5 regions participating in Advancing Coordinated Care and TeleHealth (ACT): Scotland (UK), Basque Country (ES), Catalonia (ES), Lombardy (I) and Groningen (NL); and, (iii) identify core characteristics of any given integrated care service and to generate a proposal for assessment of ser
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13

Bernard, William J. "The continuous rheoconversion process Scale-up and optimization." Link to electronic thesis, 2005. http://www.wpi.edu/Pubs/ETD/Available/etd-082305-102150/.

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14

Engman, Randy W. "Cyclone scale-up and radial gas concentration profiles." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29937.

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A two part study was undertaken to explain the performance of cyclones operated in circulating fluidized bed combustion (CFBC) systems. In the first part, collection efficiency tests were performed on a one-ninth scale polyacrylic cyclone model of the industrial scale cyclone at the 22 MWe CFBC facility at Chatham, New Brunswick. Emphasis was placed on scale-up considerations, loading effects, inlet geometry effects, and flow visualization trials. Experiments were performed at room temperature with inlet velocities between 3.7 and 5.5 m/s, solids loading between 0.05 and 7.5 mass solids/mass
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15

Hsu, Kuang-Hsin. "Scale-up of affinity chromatography for protein purifications." Ohio : Ohio University, 2000. http://www.ohiolink.edu/etd/view.cgi?ohiou1172002240.

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16

Roy, Ratul. "Pressure fluctuations and scale-up in fluidised beds." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276197.

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17

Shaaban, M. G. B. "Scale-up studies on anaerobic dispersed growth digesters." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372310.

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18

Bernard, III William J. "The Continuous Rheoconversion Process: Scale-up and Optimization." Digital WPI, 2005. https://digitalcommons.wpi.edu/etd-theses/957.

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"Semi-solid metal (SSM) processing has emerged as a preferred manufacturing method due to the superior quality associated with semi-solid castings. In recent years, the driving force to reduce process cost has led to the development of a few rheocasting (also termed slurry-on-demand) processes. These include UBE’s New Rheocasting (NRC) process [1], Idra Prince’s Semi-Solid Rheocasting (SSR) process [2], and THT’s Sub-Liquidus Casting (SLC®) process [3]. A novel slurry-making SSM process developed at ACRC/MPI, termed the “Continuous Rheoconversion Process” (CRP), is a passive liqu
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19

Geldenhuys, Armand Stefan. "Scale-up behavior of the froth stability measurement." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29876.

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Froth flotation is a widely used physio-chemical separation method in the minerals processing industry. Two distinct phases are present, namely: the pulp and froth phase. Flotation research has heavily focussed on the pulp performance; however only recently it was found that the froth performance contributes significantly to the overall flotation performance. Numerous parameters have been investigated to accurately quantify froth performance with the most notably being froth recovery. That being said, experimentally gathering data to obtain froth recovery is challenging and prone to large expe
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20

LA, NOTTE LUCA. "Scale-up of bulk-heterojunction polymer solar cells." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2013. http://hdl.handle.net/2108/203233.

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Polymer solar cells (PSCs) have recently reported a marked improvement in conversion efficiency, exceeding 10%, thus reducing the gap with more mature photovoltaic technologies. Now the transfer of such performances to the large scale has to be carried out by using industrially relevant techniques such as spray and slot die coating, and inkjet, gravure, flexographic and screen printing. This work is focused on the scale up of the PSCs by exploiting spray coating, a simple and low cost method already successfully applied to PSC layers. Firstly in literature a fully sprayed module was fabricated
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21

Lee, Karen. "Scaling up public health interventions." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/27829.

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The scale-up of effective or efficacious public health interventions to prevent chronic disease is important if population wide impacts are to be achieved. However, scale-up is complex and doesn’t happen as often as it should. This is despite growing interest in the area of research translation and scale-up by researchers and policy makers and a plethora of conceptual frameworks developed to guide the scale-up of efficacious interventions. The objectives of this thesis are to understand how scale-up may be facilitated within a research translation framework as well as in the real-world by un
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22

Collin, Anne. "Strömungsmechanische Charakterisierung des Ringwirbelschichtreaktors im Hinblick auf Scale-up." Göttingen Cuvillier, 2009. http://d-nb.info/992645239/04.

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23

Winfield, Jonathan. "Scale-up of microbial fuel cells for wastewater treatment." Thesis, University of the West of England, Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572852.

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For decades microbial fuel cells (MFCs) have offered the potential to treat wastewater while concomitantly producing power, but to date scale-up has not been achieved. The goal for this thesis was initially to explore the capabilities of MFCs in the laboratory and then to test the technology in the wastewater treatment environment. The aim was to operate the demonstrator in an existing process, without altering infrastructure or adding extra energy (Le. pumping). Laboratory work yielded novel findings helping to achieve the thesis objective while also contributing to MFC knowledge. Investigati
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24

Hoffmann, Achim [Verfasser]. "Scale-up von Reaktivrektifikationskolonnen mit katalytischen Packungen / Achim Hoffmann." Aachen : Shaker, 2005. http://d-nb.info/1181614651/34.

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25

Francis, Baker. "Scale-up and operations of a vertical stirred mill." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/46044.

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Stirred media mills are relatively new to mining industry, and several new technologies have been developed such as the VXPmill (vertical stirred mill). There is little technical understanding of optimizing and scaling-up of the VXPmill. This thesis addresses both of these issues and therefore supports commercial applications of this vertical stirred mill. Stirred media mills are influenced by a great number of operating variables. A study was conducted to understand the influence of mill speed, feed particle size and, slurry density and rheology on the VXPmill performance. For scale-up, a s
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26

Thomas, Sara. "Experimental design and scale-up methods for micellar floods." Thesis, University of Birmingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420520.

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27

Nieves, Remacha María José. "Microreactor technology : scale-up of multiphase continuous flow chemistries." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/91068.

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Thesis: Sc. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2014.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Microreactors have been demonstrated to provide many advantages over conventional process technologies for the synthesis of chemical compounds and kinetic studies at the laboratory scale. High heat and mass transfer rates, rapid mixing, and higher selectivities and conversions can be achieved in these microdevices thanks to the small characteristic dimensions, enabling the synthesis of compounds that cannot be synth
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28

Ani, Christian C. "Flow patterns, performance and scale-up of distillation trays." Thesis, Aston University, 1988. http://publications.aston.ac.uk/10234/.

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This work is concerned with the nature of liquid flow across industrial sieve trays operating in the spray, mixed, and the emulsified flow regimes. In order to overcome the practical difficulties of removing many samples from a commercial tray, the mass transfer process was investigated in an air water simulator column by heat transfer analogy. The temperature of the warm water was measured by many thermocouples as the water flowed across the single pass 1.2 m diameter sieve tray. The thermocouples were linked to a mini computer for the storage of the data. The temperature data were then trans
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29

Foster, Kennith E., N. Gene Wright, and Susan Fitzgerald Fansler. "Guayule Natural Rubber Commercialization: A Scale-Up Feasibility Study." Office of Arid Lands Studies, University of Arizona (Tucson, AZ), 1991. http://hdl.handle.net/10150/303352.

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Conducted under USDA Agreement No. 58-3159-7-11 Guayule Natural Rubber Program<br>Introduction: The United States imports 100 percent of its natural rubber. Ninety-two percent of our natural rubber production is concentrated in Southeast Asia, which is subject to interruptions through political action or direct military intervention. Natural rubber, a critical and strategic material, is necessary in such articles as aircraft and ground vehicle tires, medical supplies, resilient mounts, and certain acoustical applications. Synthetic elastomers cannot meet performance requirements in these areas
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30

Khadem, Hamedani Behnam. "Design, Scale-up and Optimization of Double Emulsion Processes." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1097/document.

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De nos jours, les émulsions doubles se trouvent dans de nombreuses applications dans différents domaines, tels que le domaine alimentaire, les produits cosmétiques, les produits chimiques ou biochimiques. Dans les produits alimentaires par exemple, les émulsions doubles peuvent permettre d’encapsuler des arômes ou de réduire la teneur en matières grasses. La littérature manque cependant de compréhension globale de ces systèmes. La modélisation peut améliorer la compréhension d'un système et permettre d'optimiser les conditions de fonctionnement afin d'améliorer la qualité du produit. Dans ces
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31

Cavinato, Mauro. "High shear wet granulation: process understanding and scale up." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3427414.

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Among all the powder agglomeration processes, high shear wet granulation is one of the most commonly used techniques. It consists of the agglomeration of different powders through the addition of a granulating fluid and a vigorous mixing. Industries often turn to high shear granulation mainly to avoid segregation of critical components in a powder mixture, improve flowability and compactibility. Despite the great importance of this technique in many industrial activities, it is not totally clear how changes in the initial powder mixture or in process variables can affect the final product prop
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32

Daniel, Michael John. "HPGR model verificatioin and scale-up / by Michael John Daniel." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17397.pdf.

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33

Dell'Ava, Peter Mario Dell'Ava P. M. "Die produkteverteilung einer mischungsmaskierten Reaktion beim Scale-up von Rührkesseln /." [S.l.] : [s.n.], 1985. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=7810.

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34

Prasanna, Praveen Ram Menta. "A study and scale-up of desalination via membrane distillation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0023/MQ50653.pdf.

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35

Baten, Jasper Martijn van. "CFD: a design and scale-up tool for multiphase reactors." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/55357.

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36

Glover, Richard D. "Permanganate passivation of pyrite containing ores scale up and characterization /." abstract and full text PDF (free order & download UNR users only), 2007. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1446427.

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37

Davis, Van Leslie. "Characterization and scale-up of microbubble generation in column flotation." Thesis, This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-03242009-040658/.

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38

Chen, Zhiwei. "Hydrodynamics, stability and scale-up of slot-rectangular spouted beds." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/610.

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Slot-rectangular spouted beds, with rectangular cross-section and slotted gas inlets, have been proposed as a solution to overcoming scale-up difficulties with conventional axisymmetric spouted beds. They can be utilized in gas/particle processes such as drying of coarse particles and coating of tablets. However, application of this spouted bed was limited because of instability and insufficient hydrodynamic studies. The present work is therefore aimed at the study of hydrodynamics, stability and scale-up of slot-rectangular spouted beds. The hydrodynamic study was carried out in four slot-re
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39

Galmes, Meerhoff Carolina. "Novel aliphatic hyperbranched polyurethanes : synthesis, characterisation, scale-up and properties." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420591.

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40

Ortega-Rivas, Enrique. "Dimensionless scale-up of hydrocyclones for separation of concentrated suspensions." Thesis, University of Bradford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253983.

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41

Zulqarnain, Kamran. "Scale-up of affinity separation based on magnetic support particles." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313426.

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42

Gwele, Zuqaqambe. "Scale-up dynamics for the photocatalytic treatment of textile effluent." Thesis, Cape Peninsula University of Technology, 2018. http://hdl.handle.net/20.500.11838/2761.

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Thesis (Masters of Engineering in Chemical Engineering)--Cape Peninsula University of Technology, [2018].<br>Enhancing the efficiency of large scale photocatalytic systems has been a concern for decades. Engineering design and modelling for the successful application of laboratory-scale techniques to large scale is obligatory. Among the many fields of research in heterogeneous photocatalysis, photocatalytic reaction engineering can initiate improvement and application of conservative equations for the design and scale-up of photocatalytic reactors. Various reactor configurations were considere
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43

Hall, Steven. "Scale-up of emulsification in in-line rotor–stator mixers." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4045/.

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The power draw and emulsification performance of in-line rotor-stator mixers were investigated experimentally and theoretically, to predict droplet size as a function of process and formulation variables and to establish scale-up rules. The effect of process conditions, three mixer scales and thirteen rotor-stator geometry configurations on emulsification performance were investigated. Emulsions of a wide range of silicone oil viscosities of varying phase volumes, dispersed in aqueous surfactant and non-surfactant solutions were studied. For lab to factory scale in-line rotor-stator mixers, th
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44

Pascoe, Jonathan Neil. "A study of scale-up methodologies for the filter cycle." Thesis, Loughborough University, 2000. https://dspace.lboro.ac.uk/2134/36023.

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This project was a joint venture between Loughborough University, the academic investigator, and ICI, the industrial sponsor. The aim was to develop and validate filter cycle scale-up methodologies, based on laboratory experiments at Loughborough and full-scale plant work at several ICI sites. Two ICI products, which experience processing problems during filtration, were chosen for assessment. They were a catalyst material (predominately iron oxide), processed by Synetix using rotary vacuum filters (RVFs), and titanium dioxide (TiO2) processed by Tioxide using a diaphragm filter press. A numbe
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45

Isaksson, Adam. "Evaluation of Scale-up Model for Flotation with Kristineberg Ore." Thesis, Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-70117.

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The objectives of this project were to survey the flotation circuit of the Boliden concentrator, mass balance collected data and evaluate a scale-up model for laboratory flotation results. The model assumes that half of the recovery to cleaner middlings in a standard laboratory test would report to the final concentrate if it were done in closed circuit, as is the case in a full-scale plant. It has been used by Boliden Mineral AB since 1982 but its accuracy had not been studied since 1986. The model can be categorised as of open circuit type with scale-up factors. The project was based on a co
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46

Yeboue, Kouadio Yves. "Peptide Synthesis by Mechanochemistry : From Fundamental studies to Scale-Up." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTS077.

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Compte tenu du durcissement des politiques environnementales vis-à-vis des polluants produits par l’industrie chimique et de la demande croissante de la part des consommateurs et des citoyens, il est impératif de trouver des méthodes alternatives aux procédés utilisant des quantités importantes de solvants et réactifs nocifs pour la santé et l’environnement. Les méthodes classiques de synthèse de peptides en font partie et nécessitent impérativement des améliorations. Ce manuscrit décrit les récents développements des procédés mécanochimiques en synthèse peptidique, procédés qui permettent un
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47

Salin, Irene. "Scale-up studies for thermo-oxidative stability of polymeric composites /." Thesis, Connect to this title online; UW restricted, 1994. http://hdl.handle.net/1773/9871.

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48

Yeh, Thomas M. "Syngas chemical looping particle production scale up and kinetics investigation /." Connect to resource, 2009. http://hdl.handle.net/1811/36976.

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49

Tuomaranta, J. (Jöns). "Resource allocation of high-growth firms in scale-up phase." Master's thesis, University of Oulu, 2019. http://jultika.oulu.fi/Record/nbnfioulu-201906052436.

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Abstract. High-growth firms are important for economic growth and employment points of view, which have been recognized by multiple studies. The purpose of this research is to gain new knowledge of the resource allocation of high-growth firms in general and especially during their scale-up phase. The specific interest of this research is how functional resources, research & development (R&D) and marketing & sales, are allocated within Finnish high-growth firms. The world-level reference for the marketing & sales and R&D investment levels are US high-growth firms. Therefore, US high-growth firm
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50

Stoker, Emily B. "Comparative Studies on Scale-Up Methods of Single-Use Bioreactors." DigitalCommons@USU, 2011. https://digitalcommons.usu.edu/etd/889.

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This study was performed to increase knowledge of oxygen mass transfer (kLa) and mixing times in the scale-up of disposable bioreactors.Results of oxygen mass transfer studies showed kLa to increase with increasing agitation and aeration rates. By maintaining a scale-up constant such as gassed power to volume or shear, an almost constant kLa was achieved during scale-up from 50 to 2000 L. Using the scale-up constant Pg/V resulted in statistically higher kLa values at greater reactor volumes. Mixing times were revealed to be significantly affected by agitation, but not by the aeration rates tes
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