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1

Burgemeister, Katja. "Hydrierung im invertierten Zweiphasensystem scCO₂/H₂O". [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=97969941X.

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2

Imran, ul-haq Muhammad. "Synthesis of fluorinated polymers in supercritical carbon dioxide (scCO₂)". Phd thesis, Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2008/1986/.

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For the first time stabilizer-free vinylidene fluoride (VDF) polymerizations were carried out in homogeneous phase with supercritical CO₂. Polymerizations were carried out at 140°C, 1500 bar and were initiated with di-tert-butyl peroxide (DTBP). In-line FT-NIR (Fourier Transform- Near Infrared) spectroscopy showed that complete monomer conversion may be obtained. Molecular weights were determined via size-exclusion chromatography (SEC) and polymer end group analysis by 1H-NMR spectroscopy. The number average molecular weights were below 104 g∙mol−1 and polydispersities ranged from 3.1 to 5.7 depending on DTBP and VDF concentration. To allow for isothermal reactions high CO₂ contents ranging from 61 to 83 wt.% were used. The high-temperature, high-pressure conditions were required for homogeneous phase polymerization. These conditions did not alter the amount of defects in VDF chaining. Scanning electron microscopy (SEM) indicated that regular stack-type particles were obtained upon expansion of the homogeneous polymerization mixture. To reduce the required amount of initiator, further VDF polymerizations using chain transfer agents (CTAs) to control molecular weights were carried out in homogeneous phase with supercritical carbon dioxide (scCO₂) at 120 °C and 1500 bar. Using perfluorinated hexyl iodide as CTA, polymers of low polydispersity ranging from 1.5 to 1.2 at the highest iodide concentration of 0.25 mol·L-1 were obtained. Electrospray ionization- mass spectroscopy (ESI-MS) indicates the absence of initiator derived end groups, supporting livingness of the system. The “livingness” is based on the labile C-I bond. However, due to the weakness of the C-I bond perfluorinated hexyl iodide also contributes to initiation. To allow for kinetic analyses of VDF polymerizations the CTA should not contribute to initiation. Therefore, additional CTAs were applied: BrCCl3, C6F13Br and C6F13H. It was found that C6F13H does not contribute to initiation. At 120°C and 1500 bar kp/kt0.5~ 0.64 (L·mol−1·s−1)0.5 was derived. The chain transfer constant (CT) at 120°C has been determined to be 8·10−1, 9·10−2 and 2·10−4 for C6F13I, C6F13Br and C6F13H, respectively. These CT values are associated with the bond energy of the C-X bond. Moreover, the labile C-I bond allows for functionalization of the polymer to triazole end groups applying click reactions. After substitution of the iodide end group by an azide group 1,3 dipolar cycloadditions with alkynes yield polymers with 1,2,3 triazole end groups. Using symmetrical alkynes the reactions may be carried out in the absence of any catalyst. This end-functionalized poly (vinylidene fluoride) (PVDF) has higher thermal stability as compared to the normal PVDF. PVDF samples from homogeneous phase polymerizations in supercritical CO₂ and subsequent expansion to ambient conditions were analyzed with respect to polymer end groups, crystallinity, type of polymorphs and morphology. Upon expansion the polymer was obtained as white powder. Scanning electron microscopy (SEM) showed that DTBP derived polymer end groups led to stack-type particles whereas sponge- or rose-type particles were obtained in case of CTA fragments as end groups. Fourier-Transform Infrared spectroscopy and wide angle X-ray diffraction indicated that the type of polymorph, α or β crystal phase was significantly affected by the type of end group. The content of β-phase material, which is responsible for piezoelectricity of PVDF, is the highest for polymer with DTBP-derived end groups. In addition, the crystallinity of the material, as determined via differential scanning calorimetry is affected by the end groups and polymer molecular weights. For example, crystallinity ranges from around 26 % for DTBP-derived end groups to a maximum of 62 % for end groups originating from perfluorinated hexyl iodide for polymers with Mn ~2200 g·mol–1. Expansion of the homogeneous polymerization mixture results in particle formation by a non-optimized RESS (Rapid Expansion from Supercritical Solution) process. Thus, it was tested how polymer end groups affect the particles size distribution obtained from RESS process under controlled conditions (T = 50°C and P = 200 bar). In all RESS experiments, small primary PVDF with diameters less than 100 nm without the use of liquid solvents, surfactants, or other additives were produced. A strong correlation between particle size and particle size distribution with polymer end groups and molecular weight of the original material was observed. The smallest particles were found for RESS of PVDF with Mn~ 4000 g·mol–1 and PFHI (C6F13I) - derived end groups.
Erstmalig gelang es, stabilisatorfreie Vinylidenfluorid (VDF)-Polymerisationen in homogener Phase mit überkritischem CO₂ (scCO₂) bis zu vollständigem Monomerumsatz durchzuführen. Die Homogenität während der Polymerisation wurde durch in-line Fourier-Transform Nahinfrarot Spektroskopie beobachtet. Für Polymerisationen bei 140 °C und 1500 bar wurde Di-tert-butylperoxid (DTBP) als Initiator verwendet. Es wurden Polymere mit einem Zahlenmittel der Molmasse kleiner 104 g·mol–1 und Polydispersitäten zwischen 3.1 und 5.7. erhalten. Um isotherme Reaktionen zu ermöglichen, wurden CO₂-Gehalte zwischen 61 und 83 wt.% verwendet. Die für die homogene Reaktionsführung erforderlichen hohen Drücke und Temperaturen haben keinen Einfluss auf die Mikrostruktur des Polymers. Zur Verringerung der Initiatorkonzentration wurden weitere Polymerisationen unter Verwendung von Kettentransferreagenzien (CTA) bei 120 °C und 1500 bar in homogener Phase mit scCO₂ durchgeführt. Perfluoriertes Hexyliodid als CTA ermöglicht kontrollierte radikalische Polymerisationen, wobei Polymere mit geringer Polydispersität zwischen 1.5 und 1.2 erhalten wurden. Endgruppenanalyse mit Elektronenspray-Ionisations-Massen¬spektro¬metrie (ESI-MS) zeigte, dass keine Initiatorendgruppen im Polymer enthalten sind. Diese Beobachtung unterstützt den lebenden Charakter der Polymerisationen und basiert auf einer labilen C-I-Bindung im Polymer. Aufgrund der schwachen C-I-Bindung trägt das perfluorierte Hexyliodid (C6F13I) auch zur Initiierung bei. Polymerisationen in Gegenwart von BrCCl3, C6F13Br und C6F13H zeigten, dass nur C6F13H keinen Beitrag zur Initiierung leistet. Bei 120 °C und 1500 bar wurde ein kp/kt0.5 von ~ 0.64 (L·mol−1·s−1)0.5 bestimmt, wobei kp der Wachstums- und kt der Terminierungsgeschwindigkeitskoeffizient sind. Die Kettentransfer¬konstanten (CT) bei 120°C betragen 8·10−1, 9·10−2 und 2·10−4 für C6F13I, C6F13Br und C6F13H. Die Änderung der CT-Werte lässt sich mit der zunehmenden Bindungsenergie in der Reihe C-I, C-Br und C-H erklären. Die labile C-I-Bindung ermöglicht eine Funktionalisierung des Polymers durch Click-Reaktionen. Nach Substitution der Iodid-Endgruppe durch eine Azidgruppe erfolgte eine katalysatorfreie 1,3-dipolare Cyclaoaddition mit Alkinen zu Polymeren mit 1,2,3-Triazol-Endgruppen. Dieses endfunktionalisierte PVDF besitzt im Vergleich zu konventionellem PVDF eine höhere thermische Stabilität. Nach der Expansion der Polymerisationsmischung mit scCO₂ auf Umgebungsbedingungen lag das Polymer als weißes Pulver vor, das im Hinblick auf z.B. Polymerendgruppen, Kristallinität, Gestalt und Größe der Partikel untersucht wurde. Rasterelektronenmikroskopie zeigte, dass Polymere mit DTBP-Endgruppen zu stapelförmigen Partikeln führen, während bei CTA-Fragmenten als Endgruppen schwamm- oder rosenartige Partikel erhalten wurden. Ergebnisse der FT-IR Spektroskopie und Weitwinkelröntgenbeugung zeigten, dass der höchste Gehalt an β-phasigem Material, der für die Piezoelektrizität des PVDF verantwortlich ist, für PVDF mit Initiatorendgruppen erhalten wurde. DSC (Differential Scanning Calorimetry) Messungen ergaben zudem, dass der Kristallinitätsgrad durch Endgruppen und Polymermasse beeinflusst wird. Die Expansion der homogenen Polymermischung kann als nicht-optimierter RESS-Prozess (Rapid Expanison from Supercritical Solution,) angesehen werden. Aus RESS Experimenten unter kontrollierten Bedingungen wurden jeweils nanoskalige primäre PVDF-Partikel ohne Verwendung von Lösungsmitteln, Tensiden oder anderen Additiven erhalten. Es besteht ein enger Zusammenhang zwischen einerseits der Partikelgröße und der Partikelgrößenverteilung und andererseits der Polymerkonzentration in scCO₂ vor der Expansion, bestimmt durch Polymerendgruppen und Molmassen der eingesetzten Materialien.
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3

Zhang, Ziyun [Verfasser]. "Asymmetrische katalytische Hydrierung in Systemen IL/scCO2 und SILP/scCO2 / Ziyun Zhang". Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2015. http://d-nb.info/1066813728/34.

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4

NIAR-DINEDANE, WAFFA. "Equites et automates en sccs". Paris 7, 1988. http://www.theses.fr/1988PA077129.

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A l'aide d'une variante des automates de muller, les t-automates, sont decrites des differentes sortes d'equite pour une classe de processus de calcul synchrone des systemes communicants, a savoir, la classe des processus strictement reguliers
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5

Niar, Wafâa. "Equités et automates en SCCS". Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37616987d.

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6

Weber, Markus. "Apparate einer SCWO-Anlage und deren Leistungsfähigkeit /". Zürich, 1997. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=11967.

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7

Abate, Giuseppe. "Caratterizzazione dell'immunocomplesso SCCA-IgM: un nuovo biomarker per la diagnosi precoce dell'epatocarcinoma". Thesis, Università degli Studi di Catania, 2011. http://hdl.handle.net/10761/208.

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L'epatocarcinoma e' uno dei piu' importanti problemi sanitari al mondo per la sua elevata incidenza e per la prognosi infausta. Il marcatore sierologico attualmente utilizzato per rilevare l'HCC fetoproteina (AFP). Altri biomarcatori, presenti nel fegato e/o nel siero dei pazienti sono stati proposti come marcatori alternativi o complementari all'AFP. Uno di questi e' l'immunocomplesso SCCA-IgM, presente nel siero di pazienti con HCC ed anche nei pazienti con cirrosi ad elevato rischio di sviluppare tumore epatico. SCOPO DELLO STUDIO Obiettivo del presente studio e' stata la caratterizzazione della specificita' del dosaggio dell'SCCA-IgM nei pazienti cirrotici o gia' portatori di epatocarcinoma in rapporto alla presenza in circolo di altri immunocomplessi, quali il fattore reumatoide. PAZIENTI E METODI Sono stati complessivamente arruolati 57 pazienti, di cui 12 pazienti con diagnosi di epatocarcinoma e 45 pazienti affetti da cirrosi epatica. Il biomarcatore SCCA-IgM e' stato dosato nel siero mediante test ELISA, mentre il Fattore Reumatoide e' stato dosato nei campioni corrispondenti mediante metodo nefelometrico. Sono state quindi condotte analisi statistiche utilizzando test non parametrici. RISULTATI I risultati ottenuti dimostrano che nei pazienti con HCC non esiste alcuna correlazione tra la positivita' per SCCA-IgM e per il FR (r=0,1). Nei pazienti cirrotici la reattivita' SCCA-IgM era associata a FR nel 24% dei casi, con grado di correlazione moderato tra i livelli dei rispettivi parametri (r=0,58), specialmente all'interno del sottogruppo dei pazienti con cirrosi HCV-correlata (r=0.71). CONCLUSIONI La reattivita' del nuovo biomarcatore SCCA-IgM non risulta correlata alla presenza di FR nei pazienti con HCC, mentre l'utilizzo del test per la sorveglianza dei pazienti cirrotici, specie nei casi dovuti ad infezione da HCV, potrebbe essere limitato in una frazione dei pazienti da una moderata correlazione coi livelli in circolo di FR.
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8

Paula, Amanda Souza de. "Um estudo comparativo entre os sistemas OFDM e SCCP". Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/3/3142/tde-11082010-162504/.

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Este trabalho trata da comparação entre os sistemas OFDM (orthogonal frequency division multiplexing) e SCCP (single carrier with cyclic prefix). Tais sistemas são analisados em função da ordem da modulação, da sensibilidade em relação à taxa de codificação de canal e do tipo de entrelaçamento utilizado. A comparação é efetuada através da adoção de um arcabouço que provê uma abordagem universal para o tratamento de ambos os sistemas. São obtidos resultados teóricos, explorando características de convexidade de funções, e resultados a partir de simulação Monte Carlo. Os sistemas são comparados, principalmente, em termos de BER (bit-error rate). Entretanto, também são realizadas comparações em termos de probabilidade de outage por cutoff rate e da SNR (signal to noise ratio) efetiva na saída do equalizador. Finalmente, os sistemas ainda são avaliados quanto à sensibilidade a erros de estimação de canal.
This work deals with the comparison between the OFDM (orthogonal frequency division multiplexing) and SCCP (single carrier with cyclic prefix). These systems are analyzed as a function of the modulation order, the sensitiveness to the channel coding rate and to the interleaver configuration. The comparison is accomplished by means of a system model that leads to an universal framework to both analyzed systems. Theoretical results are obtained exploring convexity properties of functions. In addition, some results provided by Monte Carlo simulation are also presented to complement the analysis. The systems are compared mainly in terms of the BER (bit-error rate). Moreover, comparisons in terms of outage probability obtained by cutoff rate and in terms of the effective SNR (signal to noise ratio) at the equalizer output are also provided. Finally, the systems will be compared when channel estimation error are presented at the receiver.
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9

Vieira, Ricardo Jorge Pereira. "Estudo dos limites na capacidade de transmissão em SCFO". Master's thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/7759.

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Mestrado em Engenharia Electrónica e Telecomunicações
A constante necessidade de aumentar a capacidade de transmissão de dados nos sistemas ópticos impõe uma incessante procura do melhor desempenho, eficiência e qualidade possíveis, de modo a tirar o melhor proveito das potencialidades das fibras ópticas. Neste contexto, torna-se importante conhecer e comparar os principais formatos de modulação existentes, de modo a que, para uma dada situação de transmissão prática, com um determinado ritmo de transmissão e distância associada, seja possível fazer a melhor escolha do formato de acordo com as necessidades. Este é o principal objectivo deste trabalho. Os formatos estudados nesta dissertação são o Non Return to Zero (NRZ), Return to Zero (RZ), Duobinário (DB), Vestigial Side Band (VSB), Quadrature Phase Shift Keying (QPSK), Diferential Quadrature Phase Shift Keying (DQPSK) bem como o Quadrature Amplitude Modulation com 4 e 6 bits codificados por símbolo (16-QAM e 64-QAM respectivamente) e ritmos de transmissão de 2.5, 10, 20 e 40 Gbps, observando-se as distâncias máximas para cada caso. De modo a fazer o estudo comparativo entre estes formatos foram realizadas uma série de simulações, através do VPISystemsTM, sob as mesmas condições de frequência de funcionamento (nomeadamente o parâmetro da dispersão e PMD das fibras, extintion ratio dos moduladores Mach-Zehnder e potência óptica de saída dos lasers usados) de modo a caracterizar espectralmente os formatos e análise da penalidade de potência. Tendo como base os resultados obtidos destas simulações, foi possível concluir que a ocupância espectral apresentada por cada formato é um bom indicador do seu desempenho e que para ritmos de transmissão superiores a 10Gbps a diferença de resultados entre os formatos de modulação em intensidade e os demais tornam-se muito significativas. Destes últimos formatos destacam-se os formatos de modulação em amplitude e fase (16-QAM e 64-QAM) pelo seu desempenho superior face aos restantes. Destes, o 64-QAM apresenta os melhores resultados sugerindo que um maior número de bits codificados por símbolo poderá permitir melhores resultados. Isto é apoiado pelo facto de um maior número de bits codificados por símbolo se traduzir numa eficiência espectral superior. Tendo em conta os resultados em WDM, as conclusões são idênticas. Aqui, verificou-se uma diferença significativa de desempenho entre os formatos de em intensidade e os formatos em fase ou amplitude e fase. Estes últimos, demonstraram permitir um espaçamento entre canais muito mais reduzindo quando comparado com os formatos de intensidade (aproximadamente 10 GHz face aos 35 GHz dos formatos em intensidade). No entanto, dever-se-á ter sempre em consideração a potência óptica exigida pelo formato, que tende a aumentar significativamente com a complexidade do formato. Logo, terá sempre de ser encontrado o melhor compromisso entre desempenho e potência exigida para cada situação.
The constant need for increased data transmission capacity in optic systems imposes an unending search for the best performance, efficiency and quality possible in order to take full advantage of the fiber optics’ potentialities. Keeping this in mind, it is important to know and compare the existing main modulation formats so that, in any given situation, the most informed decision can be made regarding one’s needs. This is this paper’s objective. The studied modulation formats are Non Return to Zero (NRZ), Return to Zero (RZ), Duobinary (DB), Vestigial Side Band (VSB), Quadrature Phase Shift Keying (QPSK), Diferential Quadrature Phase Shift Keying (DQPSK) as well as Quadrature Amplitude Modulation with 4 and 6 coded bits per symbol (16-QAM and 64-QAM respectively) and bit rates of 2.5, 10, 20 and 40Gbps observing the maximum distances achieved for each case. In order to undertake a comparative study between these modulation formats, a series of simulations where made, using VPISystemsTM, under similar circumstances characterizing the optical spectrum and power penalty of each modulation format (namely the fiber’s dispersion parameter and PMD, Mach-Zehnder modulators’ extintion ratio and the lasers’ optical output power).Basing on the simulation’s results, it was possible to conclude that the optical spectrum’s width is an important indicator of a modulation format´s performance and that for bit rates superior to 10Gbps, the difference in results between intensity modulation formats and all the others studied formats becomes meaningful. Considering these last formats, the ones showing the best results are the amplitude and phase modulation formats (16-QAM and 64-QAM). From these two it is the 64-QAM which shows the best performance suggesting that an increased number of encoded bits per symbol could lead to better results. This is supported by the fact that a superior number of encoded bits per symbol translates into a superior spectral efficiency. Considering the obtained results for WDM, the conclusions are identical. Here the performance gap between the intensity and phase or amplitude and phase formats is clear. These last formats allow for significantly inferior channel spacing when compared to the intensity modulation formats (approximately 10 GHz compared to 35 GHz from the intensity formats). However, one should keep in mind that the required optical power (even for a back-to-back situation) tends to increase with the complexity of the modulation format in cause. Therefore, the best compromise between required performance and required optical power should be found for each particular situation.
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10

Kosuri, Madhava Rao. "Polymeric membranes for super critical carbon dioxide (scCO2) separations". Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/28242.

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Thesis (M. S.)--Chemical Engineering, Georgia Institute of Technology, 2009.
Committee Chair: William J. Koros; Committee Member: Amyn Teja; Committee Member: Carson Meredith; Committee Member: Sankar Nair; Committee Member: Wallace W. Carr.
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11

Lozano-Perez, Sergio. "TEM crack tip investigations of SCC". Thesis, University of Oxford, 2002. http://ora.ox.ac.uk/objects/uuid:7e503ff9-782a-4f74-b184-dddaa96e03e2.

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Over the last few years, TEM has become a powerful technique to study cracks and specially crack tips. However, the number of publications including TEM results has not grown as it was expected. The main reason for this might be difficulties in the sample preparation. In this work we present a novel FIB sample preparation technique which has proved to be an ideal tool for preparing cross sectional samples containing crack tips. The morphology of intergranular stress corrosion cracking (IGSCC) has been investigated in Alloy 600 subjected to constant load and slow strain rate tests in simulated primary circuit pressurized water reactor conditions. Cracks were observed to nucleate at high-angle grain boundaries and propagate to depths of a few tens of micrometer along such boundaries, still in the initiation stage. Electron diffraction, energy dispersive x-ray (EDX) and electron energy loss spectroscopy (EELS) have been used to identify the different corrosion products and precipitates. Elemental mapping was employed to reveal changes in composition in the crack tip area. Major observations at cracks and grain boundaries include: the presence of different oxides in different locations, differences in grain boundary oxides and open crack/free surface oxides. These observations suggest that IGSCC involves oxygen diffusion through a porous oxide region along grain boundaries to the bare metal. This is a novel concept that offers an alternative to previous mechanisms proposed in the literature e.g. H embrittlement, slip-dissolution, etc., for which no supporting evidence has been found.
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12

Gajdoš, Jan. "Samozhutnitelné betony SCC pro monolitické konstrukce". Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2015. http://www.nusl.cz/ntk/nusl-227748.

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This thesis contains two parts: theoretical and experimental. In the theoretical part are described materials for production SCC and their effect on the properties of fresh and hardened concrete. Practical part is divided into two experiments. First experiment deals with the design, production and properties of hardened SCC strength classes C16/20, C20/25 and C25/30 with high volume fly ash and inert admixtures. The main endpoints were long-term compressive strength and modulus of elasticity. Second experiment of practical part deals with designs SCC with modulus of elasticity more than 40 kN/mm2.
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13

Taher, Fadia. "Spectrométrie par transformation de Fourier des molécules ScCl et Bi2". Lyon 1, 1996. http://www.theses.fr/1996LYO10137.

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Le travail presente dans cette these se rapporte a l'etude des etats electroniques de sccl. Cette molecule est produite apres chauffage a 1500 k d'un melange de scandium metallique et de cacl#2 en presence d'argon. L'analyse des spectres d'emission thermique et de fluorescence induite par laser a permis de mettre en evidence six etats singulets et deux etats triplets. Ainsi, les constantes moleculaires de tous les etats singulets situes a une energie inferieure a 22500 cm#-#1 sont determinees. La seconde partie est consacree a la molecule bi#2. Dans cette etude, on apporte des informations essentielles sur l'etat fondamental et les premiers etats excites
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14

Brandenbusch, Christoph [Verfasser]. "Downstream processing in biphasic biocatalysis by means of scCO2 / Christoph Brandenbusch". München : Verlag Dr. Hut, 2012. http://d-nb.info/1020299304/34.

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15

Romão, Joana Isabel Sobral. "Development of cyclodextrin-hydrogel polymeric systems in scCO2 for drug delivery". Master's thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/6134.

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Thesis for the Degree of Master of Science in Bioorganic Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia
This work describes the studies on the development of new cyclodextrin-hydrogel systems in supercritical carbon dioxide (scCO2) with potential application in drug delivery. Three β-cyclodextrin (CDs) derivatives were synthesized: 6-monoacryloyl-β-CD, 2-monoacryloyl-β-CD and 6-monoacryloly-heptakis-(2,3-di-O-benzyl)-β-CD. Their structures were assigned by nuclear magnetic resonance (NMR), infrared (IR) and mass spectrometry (MS) using the technique of matrix-assisted laser desorption/ionisation-time-of-flight (MALDI-TOF). These functionalized β-CDs were co-polymerized in scCO2 and the resulting co-polymers were characterized by high resolution magnetic angle spinning (HR-MAS) NMR. Swelling tests were performed showing that the presence of CD decreases the swelling capacity of the corresponding co-polymers. The β-CD co-polymers were impregnated with a model drug, metronidazole, using a batch supercritical fluid impregnation process. Experiments in vitro were realized in order to evaluate the performance of the cyclodextrin-hydrogel system as drug release device at different pHs, 2.2 and 7.4. The co-polymer with 2.5 % of 2-monoacryloyl-β-CD was the one that impregnated more drug and showed more interesting results, since at pH 2.2 the release is more controlled. The effect of the percentage of β-CD in the co-polymers performance was also investigated. The co-polymer with more percentage of 2-monoacryloyl-β-CD (8.8%) showed a more controlled drug release at pH 7.4. The results with 2.5 % of β-CD indicate that the co-polymer would be more suitable for oral administration, whereas with 8.8 % would be suitable for parenteral administration.
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16

Cagol, Matteo. "L' immunocomplesso SCCA-IgM come marker prognostico del carcinoma esofago-cardiale". Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3426085.

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Introduction. Esophageal cancer is often diagnosed at an advanced stage, and has a poor prognosis. To date, no biomarkers with high sensitivity and specificity for esophageal carcinoma are available that could be used for early diagnosis. Aims and Methods. Aim of the study was to evaluate the presence of circulating SCCA-IgM immunocomplexes in the serum of patients diagnosed to have carcinoma of the esophagus and cardia, and to identify possible correlations with clinical and tumor features. SCCA-IgM levels were measured by ELISA assay (Hepa-IC, Xeptagen S.p.A.) in the serum of 92 untreated patients with squamous cell carcinoma or adenocarcinoma of the esophagus and cardia. Positivity for SCCA-IgM was defined using a cut off level of 120 U/ml. The results obtained were compared to clinical and histological variables correlated to prognosis. Results. Overall, SCCA-IgM immunocomplexes were positive in the serum of 13/92 patients (14,1%). The percentage of positivity was significantly higher in patients with lower clinical TNM stage (stage 0-1 vs stage 2-3-4: 33,3% vs 9,4%; p= 0,01); a higher percentage of positivity was found also in patients with lower pathological TNM stage, although the difference did not reach statistical significance (stage 0-1 vs stage 2-3-4: 29,4% vs 13,6%; p=0,26). No correlation was found between serum SCCA-IgM level and other clinical and histological variables. Conclusion. Serum SCCA-IgM immunocomplexes were more frequently found in patients with an early stage cancer of the esophagus and cardia.
Introduzione. Il carcinoma dell'esofago è spesso diagnosticato in fase avanzata ed ha una prognosi infausta. Attualmente non sono disponibili marcatori di diagnosi precoce con alta sensibilità e specificità . Scopo dello studio e metodi. Scopo del presente studio è di valutare la presenza dell'immunocomplesso SCCA-IgM nel siero di pazienti affetti da carcinoma esofageo e del cardias al momento della diagnosi e di identificare una eventuale correlazione clinica con diverse caratteristiche della malattia neoplastica. Mediante metodica ELISA indiretto (Hepa-IC, Xeptagen S.p.A) è stato effettuato il dosaggio sierico dell'immunocomplesso SCCA-IgM in 92 pazienti con diagnosi istologica di carcinoma squamoso o adenocarcinoma dell'esofago e del cardias, al momento della diagnosi, prima di qualsiasi trattamento oncologico. La positività per il dosaggio sierico di SCCA-IgM è stata definita per valori superiori al cut-off di 120 U/ml. I risultati del dosaggio sono stati confrontati con le variabili cliniche e istologiche correlate con la prognosi. Risultati. 13/92 pazienti (14,1%) sono risultati positivi al dosaggio sierico dell'immunocomplesso SCCA-IgM. La positività è risultata superiore nei pazienti con stadio clinico di malattia più precoce rispetto a quelli in uno stadio clinico più avanzato (stadio 0-1 vs stadio 2-3-4: 33,3% vs 9,4 p= 0,01) e nei pazienti con stadio patologico più precoce rispetto a quelli con stadio patologico più avanzato (stadio 0-1 vs stadio 2-3-4: 29.4% vs 13.6%; p=0.26). Non si è riscontrata alcuna differenza tra i livelli sierici di SCCA-IgM e le altre variabili cliniche ed istologiche studiate. Conclusione. L'immunocomplesso SCCA-IgM circolante risulta significativamente piu' presente, al momento della diagnosi, negli stadi iniziali di neoplasia esofago-cardiale.
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17

Fabo, Frida. "Spelar språkresan roll? : Fyra individers upplevelser av språkresans betydelse för deras karriärval". Thesis, Stockholms universitet, Institutionen för pedagogik och didaktik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-77329.

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The objective of the study is to examine whether the experience from language courses abroad has had any impact on the career choices for four individuals. Based on a qualitative research methodology, four semi-structured interviews have been executed. The two research questions have been answered by letting four people recount their experiences from language courses abroad linked to their self-images and career choices. The outcome is that the experiences from the language courses contributed to a more or less altered self-image. Most of all, the interpersonal abilities were fostered, which led to the formation of a self-image characterized by improved confidence in social settings. The four individuals’ self-images have then impacted their career choices, however in different ways. The perceptions of their own abilities have played an important role in their choices of career paths.
Studiens syfte är att undersöka om fyra individers upplevelser av språkresan har haft betydelse för deras karriärval. Utifrån en kvalitativ forskningsmetod har fyra semistrukturerade intervjuer genomförts. Genom att låta fyra personer berätta om sina upplevelser av språkresan kopplade till deras självbilder och karriärval har studiens två forskningsfrågor kunnat besvaras. Resultatet visar att upplevelserna av språkresan bidrog till en mer eller mindre förändrad självbild hos dessa personer. Framför allt främjades den sociala utvecklingen, vilken medförde att en självbild kännetecknad av högre tilltro till sig själv i sociala sammanhang formades. De fyra personernas självbilder har i sin tur påverkat deras karriärval, om än på olika sätt. Bilden om den egna förmågan har spelat en viktig roll i val av karriärbana.
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18

Cordoba, Benoît. "Creep and shrinkage of self-consolidating concrete (SCC)". Laramie, Wyo. : University of Wyoming, 2007. http://proquest.umi.com/pqdweb?did=1317343151&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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19

Rich, David. "On-site application of self-compacting concrete (SCC)". Thesis, Loughborough University, 2014. https://dspace.lboro.ac.uk/2134/17229.

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Self-Compacting Concrete (SCC) is a material which under its own self-weight flows to form and fill any shape, attains full compaction, without external energy input, to create a dense homogenous mass (based on Holton, 2003; The Concrete Society and BRE, 2005; Damtoft et al, 2008). It is, in respect to the history of concrete, a relatively new development, with its first UK application occurring in the late 1990s. Since then a significant amount of research has sought to understand its physical and structural properties, but there is a lack of a knowledge base on its practical application and performance in construction projects. Where it does exist, such research lacks robust and transparent data, particularly relating to the claimed attributes of the material (such as better surface finish, faster construction and lower overall costs). Using a combination of qualitative and quantitative research methods, this research investigates the construction practices employed when pouring SCC and presents new data on its practical applications. Interviews with a range of building contractors, ranging from multinationals to small UK businesses (SMEs), show that current perceptions of SCC limit its use to specific applications because practitioners see SCC as just another type of concrete . A critical examination of these attitudes led to the identification of three distinct scenarios for the use of SCC: 1. Reactive selection: in which a particular attribute of SCC provokes its use to solve a particular problem, often as a last minute substitution for conventional concrete the most common scenario. 2. Strategic change: in which the material is chosen on the basis of a balanced assessment of all its benefits and on the understanding that such benefits can only be attained if the contractor appreciates that there may be implications for the construction process a rarely experienced scenario. 3. Specification: in which there is complete acceptance of SCC as a method, not just as a material; a significant amount of early project involvement with knowledge holders, such as contractors and material suppliers, optimises the construction process. A rigorous work measurement study of live construction projects has made it possible to quantify the as-built costs of SCC for selected UK residential slab and multi-storey flat slab applications and compare this with the equivalent conventional concrete slab construction. On-site use of self-compacting concrete vi The results indicate that SCC can reduce construction times of structural topping layers of residential slabs by up to 73%, and has shown that SCC can also match, if not reduce, total as-built concrete placement costs in multi-storey applications. This new data will enable contractors, designers and specifiers to better understand the practical implications of using SCC for on-site applications, thereby leading to more potential instances of its early and planned specification, hence resulting in more of its full benefits being realised.
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20

Ignace, Richard, L. Oskinova, M. Jardine, J. Cassinelli, D. Cohen, J. F. Donati, R. Townsend y A. ud-Doula. "A Multi-Phase Suzaku Study of τ Sco". Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/6258.

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We obtained relatively high signal-to-noise X-ray spectral data of the early massive star τ Sco (B0.2V) with the Suzaku X-ray Imaging Spectrometer (XIS) instrument. This source displays several unusual features that motivated our study: (1) redshifted absorption in UV P Cygni lines to approximately +250 km s−1 suggestive of infalling gas, (2) unusually hard X-ray emission requiring hot plasma at temperatures in excess of 10 MK whereas most massive stars show relatively soft X-rays at a few MK, and (3) a complex photospheric magnetic field of open and closed field lines. In an attempt to understand the hard component better, X-ray data were obtained at six roughly equally spaced phases within the same epoch of τ Sco’s 41 day rotation period. The XIS instrument has three operable detectors: XIS1 is back-illuminated with sensitivity down to 0.2 keV; XIS0 and XIS2 are front-illuminated with sensitivity only down to 0.4 keV and have an overall less effective area than XIS1. The XIS0 and XIS3 detectors show relatively little variability. In contrast, there is a ≈4σ detection of a ≈4% drop in the count rate of the XIS1 detector at one rotational phase. In addition, all three detectors show a ≈3% increase in count rate at the same phase. The most optimistic prediction of X-ray variability allows for a 40% change in the count rate, particularly near phases where we have pointings. Observed modulations in the X-ray light curve on the rotation cycle is an order of magnitude smaller than this, which places new stringent constraints on future modeling of this interesting magnetic massive star.
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21

BOATENG, KINGSLEY A. "STUDIES ON ARABIDOPSIS PROTEINS REQUIRED FOR THE ESTABLISHMENT AND RELEASE OF SISTER CHROMATID COHESION". Miami University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=miami1185209243.

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22

Laurino, Adrien. "Intégration des alliages d'aluminium dans le câblage électrique automobile : procédés de mise en forme, microstructure et durabilité". Phd thesis, Toulouse, INPT, 2012. http://oatao.univ-toulouse.fr/7919/1/laurino.pdf.

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Cette thèse s'inscrit dans un programme de développement technologique de la Société LEONI. Ce programme de recherche a pour principal objectif de disposer, à l'issue des trois années de l'étude, d'un panel de connaissances scientifiques le plus pertinent possible sur la durabilité des alliages d'aluminium dans des environnements caractéristiques d'un faisceau électrique automobile. Il s'agit, à terme, d'intégrer, à l'échelle industrielle, l'aluminium ou l'un de ses alliages dans les câblages électriques automobiles. Après une première étape de sélection des matériaux, l'alliage retenu est un alliage d'aluminium 6101. La fabrication des faisceaux électriques automobiles nécessite l'utilisation de brins de petits diamètres qui sont obtenus, à partir d'une ébauche, par un procédé de mise en forme associant plusieurs étapes de tréfilage et de revenu. Chacune de ces étapes conditionne les propriétés de l'alliage. Les travaux réalisés dans le cadre de cette thèse ont eu pour objectif d'analyser et de quantifier l'influence des différentes étapes de ce procédé de mise en forme sur la durabilité de l'alliage 6101. Compte tenu de l'environnement en service des faisceaux électriques, deux types de sollicitation ont été considérés ; ces sollicitations sont associées à un endommagement en corrosion d'une part et à un endommagement en fatigue-corrosion d'autre part. La première partie de ces travaux est donc consacrée à une étude du comportement en corrosion en milieu contenant des ions chlorures de l'alliage d'aluminium AA 6101 à l'état métallurgique T4, correspondant à l'état microstructural du matériau d'ébauche. L'influence des traitements thermomécaniques liés au procédé de mise en forme des fils fins sur la microstructure, les propriétés mécaniques et le comportement en corrosion de l'alliage AA 6101 fait l'objet de la seconde partie des travaux. Enfin, l'influence de contraintes mécaniques cycliques sur le comportement en corrosion de l'alliage AA 6101 en milieu NaCl 0,5M a été étudiée. L'ensemble de ces résultats met en évidence un couplage environnementmicrostructure-état de contraintes avec un fort impact des traitements thermo-mécaniques sur les microstructures et donc sur les propriétés mécaniques et le comportement en corrosion du matériau.
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23

Silva, Ana Rita Bernardo Restani da. "Development of 2-oxazoline-based hydrogels and porous polyester microparticles in scCO2". Master's thesis, Faculdade de Ciências e Tecnologia, 2009. http://hdl.handle.net/10362/6023.

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Thesis submitted to Faculdade de Ciências e Tecnologia from Universidade Nova de Lisboa in partial fulfillment of the requirements for the obtention of the degree of Master of Science in Biotechnology
The emergent demand in medicine and in the biomedical field for polymers that can deliver otherwise insoluble or unstable therapeutic compounds, to reduce the amount of those compounds and to localize the delivery of potent compounds has driven research and pharmaceutical industry to invent new molecules and new synthetic approaches to produce these kinds of “smart” polymers.!! Targeted delivery of drug molecules to organs or special sites is one of the most challenging research areas in pharmaceutical sciences. Thus, in this work two different types of polymeric matrices for the controlled release of bioactive molecules were developed: a) oxazoline-based hydrogel polymers with biological responsiveness built in and b) glycerol dimethacrylate mesoporous microparticles for inhalation into the lungs. For the development of oxazoline-based hydrogels, several methods were tested to achieve the end-capping of living poly(2-ethyl-2-oxazoline) P(EtOx) with a methacrylate unit and it was found that the end-capping with triethylammonium methacrylate was the most suitable methodology for this propose. The obtained macromonomer, P(EtOxMA),was subsequently copolymerized with different percentages (25 and 80%) of glycidyl methacrylate (GMA). The copolymers were characterized by FTIR, 1H NMR and gel permeation chromatography (GPC). The low critical solution temperature (LCST) behavior of aqueous polymer solutions was investigated by turbidity measurements revealing cloud points that can be tuned from 80 to 55.7 °C by increasing the GMA content. Glycerol dimethacrylate (GDMA) mesoporous microbeads were synthesized by a single-stage free radical polymerization. The effect of added stabilizers (Krytox and Fluorolink C) was investigated. The synthesized polymers were characterized by FTIR,solid state CP-MAS 13C NMR, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Differential Scanning Calorimetry (DSC) and mercury porosimetry. Surface area was also analyzed by the Brunauer-Emmett-Teller (BET)theory. Small mass density particles (0.19-0.37 g cm-3) with controlled size (1 to 3 μm) and homogeneous morphology were obtained by the addition of stabilizers to the polymerization media. The production of the described materials was performed using the green supercritical carbon dioxide technology, leading to well defined polymers providing a sustainable alternative to organic solvents used in conventional synthesis.
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24

Bulger, Jeffrey Thomas. "The effect of microstructure on near-neutral-pH SCC". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0006/MQ59785.pdf.

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Lightfoot, James William. "The roles of SCC-2 during C. elegans meiosis". Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554218.

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Cohesin mediates sister chromatid cohesion (SCC), and its regulated association with chromatin is required to promote faithful chromosome segregation during mitosis and meiosis, as well as for the efficient repair of DNA double strand breaks (DSBs). In the mitotic cell cycle loading of cohesin requires a conserved complex containing the Scc2INipbl protein, which has also been proposed to promote binding of the cohesin-related complexes condensin and SMC-5/6. However, little is known about the factors that promote loading of cohesin and related SMC (structural maintenance of chromosomes) complexes during meiosis. During a screen for meiotic mutants in C. elegans, I isolated an allele of sec- 2, scc-2 (jql), that has allowed me to determine the roles that SCC-2 plays during meiosis. I show that during C. elegans meiosis loading of cohesin, but not condensin 11 or SMC-5/6, requires SCC-2, demonstrating that loading of condensin 11 and SMC-5/6 can be achieved by mechanisms independent of both SCC-2 and cohesin. The lack of cohesin in scc-2 mutants impairs the repair of meiotic DSBs and recombination intermediates accumulate extensively. Surprisingly, these accumulated intermediates fail to induce an apoptotic response, which is the normal outcome when persistent DNA lesions are detected by the conserved pachytene DNA damage checkpoint. I observed that this defect is caused by a failure to load the DNA damage sensor 9-1 ~ I complex onto persistent recombination intermediates in scc-2 mutants. A lack of meiotic cohesin also impairs the timely loading of the RAD-51 recombinase to irradiation-induced DSBs. These findings suggest that meiotic cohesin is required in the early steps of DSB processing and for the recruitment of checkpoint proteins to sites of DNA damage, thus revealing novel roles for cohesin.
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26

Halfen, D. T., J. Min y L. M. Ziurys. "The pure rotational spectrum of the ScO (X2Σ+) radical". ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017. http://hdl.handle.net/10150/622650.

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The rotational spectrum of ScO (X-2 Sigma(+)) has been measured in the gas phase in the frequency range 30-493 GHz using a combination of Fourier transform microwave/millimeter-wave (FTM/mmW) and submillimeter direct absorption methods. This work is the first pure rotational study of this radical. Both the ground vibrational and v=1 states were observed. ScO was created from the reaction of metal vapor, produced either by a laser ablation source or a Broida-type oven, and N2O, in the former case heavily diluted in argon. Extensive hyperfine structure was observed in the FTM/mmW data, although the spin-rotation splitting was found to be small (similar to 3 MHz). In the mm-wave spectra, however, the fine and hyperfine structure was blended together, resulting in broad, single lines for a given transition N + 1 <- N. The data were analyzed in a combined fit using the very accurate hyperfine measurements of Childs and Steimle (1988), employing a Hund's case b Hamiltonian, and an improved set of rotational and centrifugal distortion constants were determined. These measurements improve the accuracy of predicted frequencies for astronomical searches by 14-18 MHz, or 16-20 km/s, in the 1 mm region - a difference of half to a full linewidth for certain interstellar sources. This work also demonstrates the capabilities of the FTM/mmW spectrometer at 61 GHz.
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27

Li, Yuan. "Standardized physical property testing of self-consolidating concrete (SCC)". Laramie, Wyo. : University of Wyoming, 2008. http://proquest.umi.com/pqdweb?did=1679681111&sid=2&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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28

McDaniel, Caitlin Christine. "Madoff Madness: A Textual Analysis of the SEC's response to the Madoff Ponzi Scheme". Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/89486.

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On December 11, 2008, the financial world was in a panic as the United States Securities and Exchange Commission (SEC) announced the arrest of Bernard L. Madoff of Bernard L. Madoff Investment Securities, LLC, for orchestrating a $65 billion Ponzi scheme. An investigation took place into Madoff's practices, and as a result, it was revealed the SEC failed to catch Madoff years earlier as a result of its business practices. After this became known, the SEC faced reputational harm. This qualitative analysis seeks to discover through identification and analysis of themes and sub-themes of response strategies, the extent to which the SEC applied Situational Crisis Communication Theory (SCCT) in its crisis response, in order to examine SCCT's merit as a theory in government crisis communication research. This study also offers additional response strategies imposed by the SEC to suggest further expansion of SCCT in a government context.
Master of Arts
On December 11, 2008, Bernard L. Madoff, of Bernard L. Madoff Investment Securities, LLC, was charged by the United States Securities and Exchange Commission (SEC) for his role in a $65 billion fraudulent scheme. During an investigation into Madoff’s business practices, it was revealed that the SEC overlooked many red flags that could have caught Madoff years earlier. As a result, the SEC faced reputational harm. This study examined the SEC’s crisis response to the public following the news of Madoff’s arrest by applying a crisis communication theory to discover “best practices” for government agencies when dealing with a preventable crisis. This study also offers suggestions to further expand crisis communication research and crisis response strategies in a government communication setting.
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29

Hovis, Trent Alexander. "The Role of Acetylene in Carbon Nanotube Growth". Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1301327100.

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30

Mesurolle, Maël. "Modélisation numérique en vue de la conception d'un actionneur SCAO magnétohydrodynamique de précision". Phd thesis, Toulouse, INPT, 2015. http://oatao.univ-toulouse.fr/16512/1/Mesurolle_Mael.pdf.

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Cette thèse s'inscrit dans le cadre d'un projet R&T CNES. Elle concerne l'étude d'un actionneur appelé roue d'inertie, qui fait partie intégrante de l'ensemble SCAO (Système de Contrôle d'Attitude et d'Orbite). Les nouvelles roues proposées, dites Magnétohydrodynamique (MHD) à Conduction, présentent un volant d'inertie fluidique sous forme d'un canal torique, dans lequel un métal liquide conducteur à fort potentiel inertiel est mis en mouvement sous l'effet d'un champ électromagnétique. Contrairement aux roues actuelles, elles n'ont pas de roulements ni d'arbre mécanique ce qui permet un gain en espace, un éloignement idéal de la masse inertielle, et une durée de vie théoriquement illimitée. Aussi, de par la viscosité naturelle du fluide, elles ne présentent pas de non-linéarité autour de la vitesse nulle ce qui évite une perte de précision sur le contrôle du couple de réaction, et donc du pointage du satellite. Le travail réalisé pendant la thèse porte sur l'appréhension des phénomènes MHD consistant en un couplage entre les lois de la Mécanique des Fluides et celles de l’Electromagnétisme, au travers de la loi d’Ohm généralisée. A partir d'hypothèses axisymétriques, et dans le cadre des milieux incompressibles et d’un écoulement laminaire, un modèle générale 3D a pu être établie. Puis une formulation 1D cylindrique a permis une résolution analytique, et une autre en 2D axisymétrique, par résolution numérique en différences fines, a permis l'amélioration de la précision des résultats. Ce modèle a permis de comprendre que deux approches étaient possibles pour la conception et plus particulièrement la commande de l'actionneur. Cette résolution, faisant l'objet du développement d'un code numérique, a d'abord porté sur les équations en régime permanent, puis en temporel, afin de caractériser l'actionneur du point de vue de ses deux modes de fonctionnement. La réalisation d’un prototype a permis de quantifier la validité de la modélisation d’un point de vue dynamique.
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31

Arjomand, Eghan. "Implications of Wettability Alteration of Sandstone Rocks Using Non-fluorinated scCO2-based Silylation". Thesis, Curtin University, 2020. http://hdl.handle.net/20.500.11937/81766.

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This research has compared the multiphase flow characteristics of the CO2-brine-rock system under the strongly water-wet and CO2-wet states. It has also developed a novel scCO2-based silylation technique that can be used to induce the necessary wettability alteration to sandstone rocks. This research serves to fill an existing gap in the published literature by providing reliable experimental evidence about the effect of wettability on dynamic multiphase flow characteristics of CO2-brine system.
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32

Zakari, Musinu. "The SMC loader Scc2 promotes ncRNA biogenesis and translational fidelity in Saccharomyces cerevisiae". Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066148/document.

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Le complexe Scc2-Scc4 est essentiel pour l’association du complexe cohésine sur l’ADN. Les proteines Cohésine génèrent la cohésion entre les chromatides sœurs, ce qui est essentiel pour la ségrégation des chromosomes. Scc2 (également connu sous le nom NIPBL) est muté chez les patients atteints du syndrome de Cornelia de Lange, une maladie multi-organique caractérisée par des anomalies du développement du visage, de la developpement mental cardiaque et du tractus gastro-intestinal. Comment les mutations localisées au niveau du gène codant pour la proteine Scc2 conduisent à des anomalies du développement chez les patients n’a pas encore été élucidé. Une des hypothèses est que la liaison de Scc2 / cohésine à différentes régions du génome a une incidence sur la transcription. Chez la levure de bière, il a été montre que Scc2 se lie aux genes transcrits par l'ARN Pol III (les ARNt et spliceosomals) , ainsi qu‘aux gènes transcrits par l'ARN Pol II codant pour des petits ARN nucléolaires et nucléaires (snARN et snoARNs ) et des gènes de protéines ribosomiques. Nous rapportons ici que Scc2 est important pour l'expression de ces gènes. Scc2 et le régulateur transcriptionnel Paf1 collaborent pour promouvoir la production de Box H / ACA snoARNs qui guident la pseudouridylation des ARN y compris l'ARN ribosomal. Une mutation de Scc2 a été associée à des défauts dans la production d'ARN ribosomal, la biogenèse des ribosomes, et del’épissage. Alors que le mutant Scc2 n'a pas de défaut général de la synthèse protéique, il montre un déphasage accrue et une réduction de l’utilisation du site interne d'entrée ribosomale (IRES)/ coiffe-indépendante. Ces résultats suggèrent que Scc2 favorise normalement un programme d'expression génétique qui prend en charge la fidélité de la traduction. Nous émettons l'hypothèse que le dysfonctionnement de traduction peut contribuer au syndrome de Cornelia de Lange, qui est causé par des mutations dans Scc2
The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin generates cohesion between sister chromatids, which is critical for chromosome segregation. Scc2 (also known as NIPBL) is mutated in patients with Cornelia de Lange syndrome, a multi-organ disease characterized by developmental defects in head, limb, cognition, heart, and the gastrointestinal tract. How mutations in Scc2 lead to developmental defects in patients is yet to be elucidated. One hypothesis is that the binding of Scc2/cohesin to different regions of the genome will affect transcription. In budding yeast, Scc2 has been shown to bind to RNA Pol III transcribed genes (tRNAs, and spliceosomal), as well as RNA Pol II-transcribed genes encoding small nuclear and nucleolar RNAs (snRNAs and snoRNAs) and ribosomal protein genes. Here, we report that Scc2 is important for gene expression. Scc2 and the transcriptional regulator Paf1 collaborate to promote the production of Box H/ACA snoRNAs which guide pseudouridylation of RNAs including ribosomal RNA. Mutation of Scc2 was associated with defects in the production of ribosomal RNA, ribosome biogenesis, and splicing. While the scc2 mutant does not have a general defect in protein synthesis, it shows increased frameshifting and reduced internal ribosomal entry site (IRES) usage/cap-independent translation. These findings suggest Scc2 normally promotes a gene expression program that supports translational fidelity. We hypothesize that translational dysfunction may contribute to the human disorder Cornelia de Lange syndrome, which is caused by mutations in Scc2
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33

Zakari, Musinu. "The SMC loader Scc2 promotes ncRNA biogenesis and translational fidelity in Saccharomyces cerevisiae". Electronic Thesis or Diss., Paris 6, 2015. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2015PA066148.pdf.

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Le complexe Scc2-Scc4 est essentiel pour l’association du complexe cohésine sur l’ADN. Les proteines Cohésine génèrent la cohésion entre les chromatides sœurs, ce qui est essentiel pour la ségrégation des chromosomes. Scc2 (également connu sous le nom NIPBL) est muté chez les patients atteints du syndrome de Cornelia de Lange, une maladie multi-organique caractérisée par des anomalies du développement du visage, de la developpement mental cardiaque et du tractus gastro-intestinal. Comment les mutations localisées au niveau du gène codant pour la proteine Scc2 conduisent à des anomalies du développement chez les patients n’a pas encore été élucidé. Une des hypothèses est que la liaison de Scc2 / cohésine à différentes régions du génome a une incidence sur la transcription. Chez la levure de bière, il a été montre que Scc2 se lie aux genes transcrits par l'ARN Pol III (les ARNt et spliceosomals) , ainsi qu‘aux gènes transcrits par l'ARN Pol II codant pour des petits ARN nucléolaires et nucléaires (snARN et snoARNs ) et des gènes de protéines ribosomiques. Nous rapportons ici que Scc2 est important pour l'expression de ces gènes. Scc2 et le régulateur transcriptionnel Paf1 collaborent pour promouvoir la production de Box H / ACA snoARNs qui guident la pseudouridylation des ARN y compris l'ARN ribosomal. Une mutation de Scc2 a été associée à des défauts dans la production d'ARN ribosomal, la biogenèse des ribosomes, et del’épissage. Alors que le mutant Scc2 n'a pas de défaut général de la synthèse protéique, il montre un déphasage accrue et une réduction de l’utilisation du site interne d'entrée ribosomale (IRES)/ coiffe-indépendante. Ces résultats suggèrent que Scc2 favorise normalement un programme d'expression génétique qui prend en charge la fidélité de la traduction. Nous émettons l'hypothèse que le dysfonctionnement de traduction peut contribuer au syndrome de Cornelia de Lange, qui est causé par des mutations dans Scc2
The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin generates cohesion between sister chromatids, which is critical for chromosome segregation. Scc2 (also known as NIPBL) is mutated in patients with Cornelia de Lange syndrome, a multi-organ disease characterized by developmental defects in head, limb, cognition, heart, and the gastrointestinal tract. How mutations in Scc2 lead to developmental defects in patients is yet to be elucidated. One hypothesis is that the binding of Scc2/cohesin to different regions of the genome will affect transcription. In budding yeast, Scc2 has been shown to bind to RNA Pol III transcribed genes (tRNAs, and spliceosomal), as well as RNA Pol II-transcribed genes encoding small nuclear and nucleolar RNAs (snRNAs and snoRNAs) and ribosomal protein genes. Here, we report that Scc2 is important for gene expression. Scc2 and the transcriptional regulator Paf1 collaborate to promote the production of Box H/ACA snoRNAs which guide pseudouridylation of RNAs including ribosomal RNA. Mutation of Scc2 was associated with defects in the production of ribosomal RNA, ribosome biogenesis, and splicing. While the scc2 mutant does not have a general defect in protein synthesis, it shows increased frameshifting and reduced internal ribosomal entry site (IRES) usage/cap-independent translation. These findings suggest Scc2 normally promotes a gene expression program that supports translational fidelity. We hypothesize that translational dysfunction may contribute to the human disorder Cornelia de Lange syndrome, which is caused by mutations in Scc2
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34

Bao, Jin-Biao. "Elaboration de polypropylène ou de polystyrène à l'aide du dioxyde de carbone supercritique : procédé – microstructure – propriétés mécaniques". Thesis, Vandoeuvre-les-Nancy, INPL, 2011. http://www.theses.fr/2011INPL111N/document.

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Le moussage du polypropylène (PP) et du polystyrène (PS) par le scCO2 est étudié de manière systématique avec l’accent sur la relation entre le procédé, la microstructure et les propriétés mécaniques. La première partie de cette thèse porte sur l’amélioration de la résistance au choc du PP par cristallisation induite par le scCO2. Dans un deuxième temps, le PP fortement orienté avec des structures shish-kebab et sphérolite est utilisé pour étudier l’influence de la structure cristalline sur la nucléation et la croissance des cellules pendant le procédé de moussage sous le scCO2. Ensuite, les influences des conditions de moussage ainsi que celles des paramètres structuraux de la mousse de PS ont été étudiées. Les mousses de PS à cellules isotropes ont été comparées avec celles de PS à cellules orientées. Enfin, un procédé de moussage discontinu en deux étapes est développé afin de produire des mousses de PS à cellules bi-modales en utilisant le scCO2 en tant qu’agent de moussage. Cette structure unique de petites et grandes cellules réparties de manière homogène au travers de l’ensemble du volume de la mousse confère à cette dernière des propriétés particulières
In this work, scCO2 induced foaming of PP or PS is systematically studied with emphasis on the relationship between process, microstructure and mechanical properties. The first part of the thesis deals with the toughening of iPP by scCO2 induced crystallization for the fine separation of rigid crystalline domains and soft amorphous ones in the polymer matrix. The highly oriented iPP with “shish-kebab” and “spherulite” are then used for CO2 foaming to investigate the effect of crystalline structure on the formation of cell nucleation and growth. In addition, the effect of the foaming conditions and the cell structural parameters of PS foams on the mechanical properties are studied systematically. PS foams with isotropic cell morphology and oriented cell one are prepared. Finally, a two-step depressurization batch process is developed to produce bi-modal cell structure PS foams by using scCO2 as the blowing agent. This unique cell structure with both small and large cells homogenously distributed throughout the entire volume of the foam sample might have particular properties
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35

Andréasson, Camilla y Wall Malin Enbäck. ""Jag måste kämpa..." : Elevers perspektiv på gymnasieskolans individuella program". Thesis, Stockholm University, Department of Education, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-28458.

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Syftet med studien är att undersöka några elevers uppfattning av sin studiegång på det individuella programmet (IV). Samt belysa i vilken utsträckning utbildningen individanpassas. En kvalitativ forskningsmetod användes. Sju elever intervjuades som går sitt första år på det individuella programmet. Undersökningen belyser hur eleverna trivs på IV och vad de tycker om sin utbildning. En annan aspekt var att ta reda på hur eleverna tänker kring sin egen insats beträffande utbildningen. Resultatet visar att eleverna trivs och de har mål med sin utbildning. Samtidigt har eleverna åsikter om förbättringar när det gäller klassrumssituationen, lärare och individuella samtal. Undersökningen visar att elevens påverkan av sin studiegång är begränsad. Vår slutsats är att eleverna inte får den individuella utbildning de har rätt till.

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36

Fredin, Maria y Christina Westin. "Ung och arbetslös : Fem ungdomars röster om vägen ur arbetslösheten". Thesis, Stockholms universitet, Institutionen för pedagogik och didaktik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-59325.

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Studien vill belysa hur de undersökta ungdomarna ser på sina möjligheter att ta sig ur arbetslösheten. Gentemot teorier, publicerad litteratur och forskning har studiens syfte varit att synliggöra vad respondenterna anser sig själva kunna göra för att ta sig ur arbetslösheten, vilket stöd den anser sig behöva och hur de tänker kring sin framtid i förhållande till arbete och studier. En kvalitativ undersökningsmetod har genomförts, det har utförts intervjuer med fem arbetslösa ungdomar. I studien framkom att respondenternas tilltro till den egna förmågan påverkar deras agerande och bedömningar av sina möjligheter gällande studier och yrken. Resultatet visar att utbildning ses som en väg ur arbetslösheten och att ungdomarna utöver det se få saker de kan göra för att påverka sin situation. Av samhället vill respondenterna bli sedda och lyssnade på som de huvudaktörer de är i frågan och ur ett studie- och yrkesvägledarperspektiv ser vi det som vår uppgift att se och lyssna till individen.
The study will shed light upon how surveyed youths view their possibilities in regards to getting out of unemployment. Considering academic theory and published literature on the subject, the purpose of the study was to highlight how the respondents individually consider themselves able to commence into employment, what support systems are available to them, what they feel would be necessary or helpful, and how they think about their futures in relation to work and studies. A qualitative study was undertaking, conducting interviews with five young unemployed subjects. The examination of the results found that the respondents´ confidence in their assessment of their individual lives and decisions made. The respondents wish not to be cast aside, but listened to and seen as society sees others in opposite positions to the youths.
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37

Lambert, Maria T. "Attack of the Mommy Mafia| Examining The Honest Company's Use of Coombs' SCCT Strategies". Thesis, University of Louisiana at Lafayette, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1593182.

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A crisis can threaten the existence of an organization, and in this social media age, information is spread at lightning-fast speeds forcing crisis communication managers to work quickly to quell any unflattering press. Companies in crisis situations attempt to mitigate damage and repair reputations using crisis communication strategies, such as Coombs’ Situational Crisis Communication Theory (SCCT). This thesis explored social media as a crisis communication channel for these strategies, by studying an organizational crisis that played out almost entirely on social media, through the lens of SCCT.

This thesis used six statements made by The Honest Company during a 2013 crisis where stakeholders accused the company of bullying a working mother over trademark rights. The company’s crisis communication messages were retrieved, and by using discourse analysis the messages were examined through the guidelines of the SCCT model, which allowed categorization of the messages according to SCCT, analysis of their effectiveness, and the defining of SCCT challenges in analyzing this organizational conflict aggrandized through social media.

This study found that even though The Honest Company did not strictly adhere to SCCT’s guidelines, it was able to flourish and surpass consumer expectations after the crisis ended. The examination of this crisis offered insight into SCCT’s lack of clarity and direction concerning its crisis types, strategies, and guidelines. It also offered suggestions for more specific crisis types and the expansion of crisis types for SCCT.

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38

Kim, Hojong 1974. "An investigation of corrosion mechanisms of constructional alloys in supercritical water oxidation (SCWO) systems". Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/16636.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2004.
Includes bibliographical references (leaves 179-186).
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Supercritical water oxidation (SCWO) is a technology that can effectively destroy aqueous organic waste above the critical point of pure water. These waste feed streams are very aggressive and pose material performance issues. As potential alloys in construction of SCWO systems, nickel-base alloys are tested. Corrosion in aqueous feed streams of ambient pH values of 2, 1 and 7 is studied both at supercritical (-425⁰C) and subcritical (-300-360⁰C) temperatures with a constant pressure of 24.1MPa. Dealloying of Ni and Fe, and oxidation of Cr and Mo are observed at subcritical temperatures at a pH value of 2. At a pH value of 1, even chromium is selectively dissolved and only molybdenum forms a stable oxide at the subcritical temperature. At supercritical temperatures, normal thin oxidation occurs at both pH values of pH 2 and 7. In contrast, in the neutral pH solution, dealloying is not observed at any temperature. Stress corrosion cracking (SCC) in acidic feed streams is observed both at the supercritical and subcritical temperatures. In order to understand the corrosion mechanisms, the chemistry of a feed stream, the formation of the dealloyed oxide layer, and the level of stress are investigated.
(cont.) The suppression of dealloying at supercritical temperatures comes from the low proton concentration associated with the low dissociation constant of HCl and water. However, the growth rate of the dealloyed oxide layer at subcritical temperatures is very fast, which is primarily due to the dealloying and the high diffusivity of the nickel in this defective oxide layer. SCC at subcritical temperatures results from the dealloyed oxide layer formation along the grain boundary as intrusions, which act as a precursor to the crack initiation and propagation. SCC at the supercritical temperature is thought to result from the direct chemical attack of associated HC1 molecules. SCC is not observed in the neutral solution.
by Hojong Kim.
Ph.D.
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39

Kullberg, Johan y Felix Kullgren. ""Det är så samverkan ska fungera" : En fallstudie av hur lokala aktörer agerar när en krissituation uppstår". Thesis, Karlstads universitet, Institutionen för geografi, medier och kommunikation, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-35783.

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Abstract The purpose of this essay is to investigate how a local authority acts when anunexpected event occur. It´s done with a basis in two crisis communicationstheories; Coombs SCCT theory and Gilpin and Murphys complexity theory,which largely are each other’s opposites. To conduct the study, a case studyof the floods that hit Kristinehamn in the summer of 2014 was carried out,which gave us a good opportunity the achieve the aim of the study. Themethod used was qualitative research interviews. A total of eight people wereinterviewed, all of whom in some shape or form were involved in solving theKristinehamn crisis. Some of the questions we wanted answers to during theinterviews were if the communication between the authorities and othersword well or less well, and what it was that in that case made the communicationsuccessful or unsuccessful. The result of the study shows that the staffand the people around the staff subconsciously uses the basics of the complexitytheory, which they also think is the best suitable theory of the twoused in this study when it comes to resolving crisis in an effective way.Another result from this study was that in the minds of the people responsiblefor the handling of the crisis, this crisis was solved in the best possible way.And also that the critical factors behind this success was things directlylinked to the basics behind the complexity theory, such as the formation ofthe crisis team, the personal knowledge of the people involved and thatseveral of the crisis mangers had experience from similar events from earlierin their lives.
Sammanfattning Syftet med den här uppsatsen var att göra en undersökning av hur en lokalmyndighet agerar vid en oförutsedd händelse. Vi gör det med utgångspunkt itvå kriskommunikationsteorier; Coombs SCCT-teori och Gilpin och Murphyskomplexitetsteori, som till stor del är varandras motsatser. För att genomförastudien gjordes en fallstudie av översvämningarna som drabbade Kristinehamnsommaren 2014, vilket gav oss en bra möjlighet att uppnå syftet medundersökningen. Metoden som användes var kvalitativa forskningsintervjuer.Totalt intervjuades åtta personer, som alla på något sätt var inblandade i attlösa krisen som uppstod i Kristinehamn. Några frågor som vi ville ha svar påunder intervjuerna var bland annat om kommunikationen mellan myndigheternaoch övriga fungerade bra eller mindre bra, och vad det i sådana fall varsom gjorde kommunikationen framgångsrik eller misslyckad. Resultatet avstudien är att staben och personalen runt omkring staben omedvetet användersig av grundprinciperna i komplexitetsteorin, och också anser att den teorin ärden bäst lämpade av de två studien stöttar sig på när det handlar om atteffektivt lösa kriser. Ett annat resultat som framkom var att krisen enligt deansvariga för krishanteringen löstes på bästa tänkbara sätt, där de störstaframgångsfaktorerna var sådant som står i direkt anslutning till komplexitetsteorinsgrundtankar: samgruppering, personkännedom och att flera avkrishanterarna hade erfarenhet av liknande händelser sedan innan.
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40

Molander, Agnes y Eidenert Kim Nässlin. "Radiotystnad resulterar i fullt kaos : En studie om Malaysia Airlines kriskommunikation". Thesis, Uppsala universitet, Medier och kommunikation, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-243190.

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The purpose of this thesis is to study how Malaysia Airlines communicated during the two largest crises of 2014. Key questions to be answered are: Did organizational hypocrisy occur? If yes, in what way? Which communication strategies were used? Did the company mediate an unequivocal message and how was the information framed? Did any aggravating factors, which worsened the organization’s reputation, appear? How did Malaysia Airlines manage possible rumours? Was the word contact used as a keyword?   The method of choice is a quantitative content analysis and the material consists of 20 different analysis units. These analysis units were collected from social media and Malaysia Airlines website. The quantitative content analysis is based on the theory Situational Crisis Communication Theory, taken from PR, Strategy and Application, Managing Influence, by W. Timothy Coombs & Sherry J. Holladay. The main results displayed that Malaysia Airlines acted fast and instantly communicated with stakeholders. Short messages filled with information were dominating and social media was frequently used. The first crisis acted as an intensifier  to the second one and Malaysia Airlines’ reputation took a bad turn. Different messages were conveyed, something that could have been avoided by using only one spokesperson. The communication strategy used was a deny strategy. The organization denied having any responsibility in the crises and tried to pinpoint a scapegoat. Rumours were either completely ignored or disproved by substantial facts. Malaysia Airlines also compensated relatives, provided information and care for the concerned, as mentioned in the SCCT’s recommendations.
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41

Machala, Petr. "Optické snímání a analýza bytových měřidel". Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2015. http://www.nusl.cz/ntk/nusl-221254.

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The topic of this master’s thesis is a study and solution of problems regarding an optical recognition and home metering analysis for the following recording and statistical processing. For this required application a STMicroelectronics 32F429IDISCOVERY development board with ARM Cortex-M4 microcontroller and OmniVision OV7670 camera module was used, where a required firmware was implemented. This thesis therefore generally represents a complex solution from acquisition of images by used camera module to final analysis and data processing and building a functional prototype of the proposed sensor system.
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42

Manrique, Juarez Maria Dolores. "Micro and nanoactuators based on bistable molecular materials". Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30244/document.

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Les systèmes microélectromécaniques (MEMS) sont des dispositifs de taille micrométrique capables de transformer un signal mécanique en un signal électrique et vice-versa. Ils sont aujourd'hui largement répandus dans notre vie quotidienne pour la détection, la transformation de l'énergie et l'actionnement de dispositifs grâce à leur faible dissipation énergétique, leur réponse ultra-rapide et leur grande sensibilité. Même si depuis plusieurs décennies, les progrès technologiques ont entraîné la miniaturisation des ces dispositifs, il reste nombreux challenges à surmonter dont l'un des plus importantes est l'intégration à l'échelle nanométrique d'actionneurs à base des matériaux dit " intelligents " (à ces dimensions, les matériaux habituellement utilisés perdent leurs propriétés d'actionnement). Dans ce contexte, ce travail de thèse avait pour objectif d'explorer l'utilisation des matériaux moléculaires à transition de spin pour le développement d'actionneurs électromécaniques. Dans ce but, nous avons conçu des microleviers en silicium que nous avons recouvert par différentes molécules à transition de spin soit par sublimation, soit par " spray-coating ". Les MEMS ont été caractérisés à température et pression variables en modes dynamique et statique à l'aide d'un unique dispositif expérimental. Les résultats obtenus démontrent que les molécules à transition de spin peuvent être intégrées, à l'aide de différents procédés de fabrication, dans des dispositifs MEMS et qu'il est possible de réaliser l'actionnement à l'aide d'une source d'énergie thermique (chauffage et refroidissement) et/ou lumineuse. Simultanément, cette étude a également permis d'évaluer les propriétés mécaniques des matériaux à transition de spin (module de Young, coefficient de Poisson) qui restent mal connues
Microelectromechanical systems (MEMS) are micrometric devices able to transform a mechanical signal into an electrical one and vice-versa. In the past years they have been successfully employed in different fields of our everyday life for sensing, transducing different forms of energy and for actuating purposes thanks to their low energy dissipation, fast response and high sensibility. Even if recent technological progress has allowed a considerable miniaturization of these devices, several challenges remain. In particular the integration of smart actuating materials at the nanometric scale remains arduous because in most cases they lose their actuating properties at reduced sizes. In this context, this thesis work aimed for exploring the possibility of using molecular spin crossover materials for the development of electromechanical actuators. To this aim we have conceived silicon microcantilevers, which have been coated by various spin crossover molecules using either thermal evaporation or spray-coating methods. The MEMS have been characterized at variable temperature and pressure both in dynamical and static modes using a single experimental setup. The results prove that spin crossover molecules can be successfully integrated into silicon MEMS devices using different fabrication processes and their actuation can be achieved using either a thermal energy source or light irradiation. In parallel, this work has allowed us to extract relevant mechanical properties of spin crossover materials (Young's modulus, Poisson's ratio), which have been largely unknown previously
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43

Furlan, Ariane Silva 1986. "Functional and structural studies of proteins involved in the development and nerve signaling = FEZ1, SCOC and RARA = Estudos funcionais e estruturais de proteínas envolvidas no desenvolvimento e sinalização nervosa: FEZ1, SCOC e RARA". [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314362.

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Orientador: Jörg Kobarg
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-08-23T08:43:43Z (GMT). No. of bitstreams: 1 Furlan_ArianeSilva_M.pdf: 17272017 bytes, checksum: cc7e8f01d7f236f37a6c9c63fcb9a8f9 (MD5) Previous issue date: 2013
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Abstract: The abstract is available with the full electronic document when available
Mestrado
Bioquimica
Mestra em Biologia Funcional e Molecular
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44

de, Haas Marcel. "Moskaus nützliches Instrument? : Russland und die Shanghai-Gruppe". Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5004/.

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Russland sieht in der Shanghai-Gruppe ein wichtiges außen- und sicherheitspolitisches Instrument. Damit sollen sowohl das internationale Profil verbessert als auch militärische Interessen (Waffenexporte) umgesetzt werden. Obwohl sich das Verhältnis zu China deutlich verbesserte, ist es russisches Interesse, mittels der SCO Chinas Einfluss in Zentralasien zu begrenzen. Angesichts der strategischen Differenzen zwischen Moskau und Peking stellt sich das Problem des möglichen Bruchs der Shanghai-Gruppe.
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45

Molin, Anders y Hanna Olsson. "”Det enda säkra är att vi inte kommer att följa planen” : En kvalitativ studie av tillämpningen av kriskommunikationsteorier för att skydda anseendet". Thesis, Karlstads universitet, Avdelningen för medie- och kommunikationsvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-34992.

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The value of a good reputation for organizations is increasing today as consumers and citizens become more aware of brands. If a crisis hits an organization, there is now more to lose than before concerning reputation. Therefore the organization’s communication strategies must be developed to sustain the organization’s reputation during and after a crisis. In the field of crisis communication there are two distinguished theories which concern what an organization with help from crisis communication should do to undergo a crisis without losing its reputation. These theories are image repair theory and situational crisis communication theory (SCCT). They both offer guidelines and course of actions for a preserved reputation, the latter with a list of scenarios of crises tied to every given strategy the theory proposes. The purpose of this study is to shine light on the application of the theories among communicators in both public and private organizations. This is investigated by focusing partly on how communicators reason about focusing on the organization’s reputation in crisis communication, partly on how they feel about implementing the strategies tied to scenarios image repair theory and situational crisis communication theory advocate. To examine the question at issue, we have performed a series of interviews where our group of respondents consists of ten communicators working in public and private organizations. With every respondent we have had a long talk and tried to dig deep into how crisis communication plans are designed as well as how crisis communication is practiced. The conclusion of this study is that the basic ideas that image repair theory and situational crisis communication theory are based upon are well implemented among Swedish communicators. However, the strategies recommended by the theories are completely rejected by the communicators. Instead they say that openness is the best way to a preserved reputation, not specific strategies tied to scenarios. The communicators think that such a course of action would do more harm than good for the reputation of the organization during a crisis. No crisis looks like another and therefore it is impossible to foresee how crisis communication should be designed.
Vikten av ett gott anseende ökar mer och mer idag när konsumenter och medborgare blir mer och mer varumärkesmedvetna. Detta medför att om en organisation drabbas av en kris finns det nu mer att förlora än tidigare vad gäller anseende. Därför måste också organisationens kommunikationsstrategier följa med i utvecklingen och vara kapabla att upprätthålla anseendet under och efter en kris. På området kriskommunikation finns det två framstående teorier som berör hur en organisation med hjälp av kriskommunikation ska göra för att genomgå en kris utan att förlora anseende. Dessa teorier är image repair theory och situational crisis communication theory (SCCT). De erbjuder båda riktlinjer och tillvägagångssätt för ett bevarat anseende, den senare med en lista över krisscenarion knutna till varje given strategi teorin förespråkar. Syftet för denna studie är att belysa hur tillämpningen av teorierna ser ut bland kommunikatörer i offentlig och privat verksamhet. Detta utreds dels genom att se på hur kommunikatörer resonerar kring att i kriskommunikation fokusera på organisationens anseende, dels på vad de tycker om att implementera de strategier knutna till scenarion image repair theory och situational crisis communication förespråkar. För att undersöka ovanstående frågeställning har vi använt oss av kvalitativ samtalsintervju, där vår respondentgrupp består av tio kommunikatörer inom offentlig och privat verksamhet som har kriskommunikation som ansvarsområde inom respektive organisation. Med varje respondent har vi haft långa samtal och försökt att gå på djupet med hur kriskommunikationsplaner utformas samt hur kriskommunikation i praktiken utövas. Slutsatsen för denna studie är att grundidéerna som image repair theory och situational crisis communication theory bygger på är väl implementerade bland svenska kommunikatörers arbetssätt. Men de strategier som förespråkas av teorierna ratas fullständigt av kommunikatörerna. I stället hävdar de att öppenhet är den bästa vägen till bevarat anseende, inte specifika strategier knutna till scenarion. Ett sådant tillvägagångssätt menar kommunikatörerna skulle göra mer skada än nytta för organisationens anseende under kris. Ingen kris är den andra lik och det är därför omöjligt att förutse hur kriskommunikation ska se ut.
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46

Gustafsson, Fredrik y Niklas Johansson. "Rätt plåster i rätt tid : En fallstudie av ICAs krishantering". Thesis, Södertörns högskola, Företagsekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-32841.

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This study examines how the grocery retail company ICA handle their communication in store during a crisis and how they manage it efficiently. With contributions from theories and models from the field of crisis management this study examines how these are implemented in practice. With the help of a case study on four ICA-stores in Stockholm this study aims to see how communication during a crisis is conducted. A qualitative approach is used through four semi- structured interviews with people who hold leading positions in each store. Among those were two of them store owners, one was a store manager and one a controller. The results show that communication is one of the most important things during a crisis and that the information should be open and transparent. The conclusion is that the stores use several different communications channels, signs, verbal communication, flyers and social media. A combination of which is what is shown to be the most efficient way to handle a crisis and to be active on social media is what this study think will be an important tool in the future.
Den här studien undersöker hur dagligvaruaktören ICA sköter sin kommunikation i butik under en krissituation och hur de på ett effektivt sätt hanterar dessa händelser. Med hjälp av existerande teorier och modeller inom krishantering undersöks här om dessa implementeras i praktiken. Genom en fallstudie av fyra ICA-butiker i Stockholmsområdet har den här studien på ett kvalitativt sätt via semistrukturerade intervjuer studerat hur denna kommunikation ser ut. De intervjuade är två stycken handlare, en butikschef och en controller där samtliga har en ledande roll inom vardera ICA-butik. Resultaten visar att de intervjuade tycker att kommunikationen under en kris är av yttersta vikt och att vara öppen och transparent anses som fundamentalt. Slutsatsen är att butikerna använder sig av flera olika kanaler för att kommunicera i butik, skyltning, informera de anställda, skicka ut reklamblad samt att använda sig av sociala medier. En kombination av dessa kanaler visar sig vara ett effektivt sätt att hantera en kris och att vara aktiv på sociala medier tror den här studien kommer vara ett viktigt verktyg i framtiden.
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47

Dachelet, Darren O'Brien Schindler Anton K. "The effectiveness of self-consolidating concrete (SCC) for drilled shaft construction". Auburn, Ala, 2008. http://repo.lib.auburn.edu/EtdRoot/2008/SUMMER/Civil_Engineering/Thesis/Dachelet_Darren_26.pdf.

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Saarela, Anneli. "Kriskommunikationsstrategi och varumärke : En fallstudie av svenska Röda Korset genom dialogisk analys". Thesis, Örebro University, School of Humanities, Education and Social Sciences, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-10903.

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Title: Crisis communication strategy and brand – A case study of Swedish Red Cross

through dialog analysis

Author: Anneli Saarela

Presented: 01.06.2010

Purpose: The study addresses the subjects of crisis communication and organisational brand, in relation to stakeholders and brand reputation. The purpose of this essay is to study the dialog regarding the crisis of remunerations with the Swedish Red Cross and how the organisation responds to the criticism. An identification and analysis of the discourse regarding the brand are also included in the study. Part of the empirical material will also be used in relation to Situational Crisis Communication Theory (SCCT). This to find which strategy is most accurate to the one which the Swedish Red Cross seemingly has implemented.

Methodology: The study uses dialog analysis to gather the empirical material. The dialog of interest for this study consists of four different written texts. These texts are analysed with the help of concepts such as: content, context, intertextuality, recontextualisation and relation. Further, through these concepts the study uses a series of initial questions to start the analysis with regard to the concepts.

Theoretical perspectives: The theoretical base for this essay consists of relevant theories to crisis management and branding. These are Situational Crisis Communication Theory, crisis communication and rhetoric as well as ideas regarding identity, stakeholders and reputation. I have used these as tools in my analysis as well as to understand the concept regarding crisis and the effects on an organisation, the brand and stakeholder relationships.

Conclusions: The results show that the texts in the dialog are influenced by earlier texts to a great extent. Interesting enough the stakeholders hold the board members responsible and not the whole organisation itself. This may be because the reporting has been mainly focused on the individuals and their remunerations in the earlier stages of the crisis. In regards to rebuilding the trust and organisational brand the analysis show that the organisation should make changes regarding the members of the board, as it is those who are strongly attributed to the crisis by the interest groups. The analysis in relation to SCCT show that the Swedish Red Cross chose a strategy involving less responsibility than SCCT would have proposed. Although regarding the bolstering strategies the organisation did as SCCT would suggest and put emphasis on the earlier work the organisation has done and took advantage of its strong reputation.

Keywords: SCCT, crisis communication, brand, organisation, stakeholder

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49

Scho, Julia Tamara [Verfasser]. "Multiperspektivische und interdisziplinäre Verfahren der Romanrezeption anhand von Alfred Döblins Berlin Alexanderplatz / Julia Tamara Scho". Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1219140384/34.

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Axelsson, Sofia y Anna Vardiero. "Den mjuka sidan av anställningsbarhet". Thesis, Stockholms universitet, Institutionen för pedagogik och didaktik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-77152.

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Anställningsbarhet är ett begrepp som blommat upp under slutet på 1900-talet. Att varaanställningsbar innebär att ha förmågan att få, behålla och vid behov skaffa sig ett nytt arbete.Det finns två faktorer som påverkar en individs anställningsbarhet, formell kompetens ochinformell kompetens. Vi har intervjuat sex rekryterare i Stockholms län med syftet att belysaderas syn på hur informell kompetens påverkar anställningsbarhet. Vi har ställt öppna frågorsom bland annat syftat till att ta reda på vad som gör en individ anställningsbar när den formellakompetensen är uppfylld samt hur viktigt informell kompetens är i förhållande till formellkompetens. Resultatet av undersökningen visar att det enligt de intervjuade rekryterarna framförallt finns tre typer av informell kompetens: (1) social kompetens, (2) inställning till arbetet och(3) personlighet. Resultatet visar även att informell kompetens i många fall är viktigare änformell kompetens. Vi har också identifierat två olika tekniker för att, i en anställningsintervju,bedöma den arbetssökandes informella kompetens, den reflekterande och den intutiva.
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