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1

Prysjazhnjuk, V. "Паростки лікувальної справи тварин в Галичині". Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 77 (7 березня 2017): 158–61. http://dx.doi.org/10.15421/nvlvet7734.

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Folk veterinary medicine – an important plot of national experience, which includes rational knowledge and practical skills of domestic animals treatment. The special attention was paid to those Ukrainian animals from whom was depended the success of farming (horses, cattle, pigs, sheep). In traditional veterinary medicine are mainly used the same means as in folk medicine. The most popular were the drugs of plant origin. Frequently herbal medicine is used in combination with minerals, animal fats. Folk veterinary accumulated and some knowledge about the importance of sanitation and hygiene fo
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2

Rajapaksa, Suresh, David McIntosh, Allison Cowin, Damian Adams, and Peter-John Wormald. "The Effect of Insulin-Like Growth Factor 1 Incorporated into a Hyaluronic Acid-Based Nasal Pack on Nasal Mucosal Healing in a Healthy Sheep Model and a Sheep Model of Chronic Sinusitis." American Journal of Rhinology 19, no. 3 (May 2005): 251–56. http://dx.doi.org/10.1177/194589240501900307.

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Background Endoscopic sinus surgery (ESS) is the accepted surgical treatment for chronic refractory rhinosinusitis. Prolonged healing and adhesion formation remain common problems. This study investigates the use of a hyaluronic acid-based pack impregnated with insulin-like growth factor (IGF) 1 to facilitate more rapid and effective healing after ESS in a healthy sheep model and a sheep model of chronic sinusitis. Methods This study used 12 healthy sheep and 9 sheep with chronic sinusitis. In each sheep one side (computer randomized) was used as a control. Under endoscopic guidance, mucosal i
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3

Kaufman, Howard H. "Treatment of head injuries in the American Civil War." Journal of Neurosurgery 78, no. 5 (May 1993): 838–45. http://dx.doi.org/10.3171/jns.1993.78.5.0838.

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✓ At the time of the American Civil War (1861–1865), a great deal was known about closed head injury and gunshot wounds to the head. Compression was differentiated from concussion, but localization of lesions was not precise. Ether and especially chloroform were used to provide anesthesia. Failure to understand how to prevent infection discouraged physicians from aggressive surgery. Manuals written to educate inexperienced doctors at the onset of the war provide an overview of the advice given by senior surgeons. The Union experiences in the treatment of head injury in the Civil War were discu
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4

Newlands, Shawn D., Sreedhar Samudrala, and W. Kevin Katzenmeyer. "Surgical Treatment of Gunshot Injuries to the Mandible." Otolaryngology–Head and Neck Surgery 129, no. 3 (September 2003): 239–44. http://dx.doi.org/10.1016/s0194-5998(03)00481-9.

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OBJECTIVES: Our goal was to review and identify risk factors for complications from treatment of mandible fractures due to gunshot wounds. STUDY DESIGN AND SETTING: We conducted a retrospective review of treatment outcomes in 90 patients with gunshot wounds to the mandible treated over a 10-year period at 2 tertiary care centers. RESULTS: Our series of 90 patients with mandibular injuries due to gunshot wounds included 68 patients who underwent surgical procedures on the mandible. There were 14 complications in this group. Complications were more common in patients whose mandibles were rigidly
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5

Chierice, João, Geraldo Figueiredo, Moyses Lima-Filho, Igo Lago, Rodrigo Costa, and José Marin-Neto. "Hybrid interventional and surgical treatment of complex traumatic cardiac dagger wounds." Journal of Transcatheter Interventions 29 (July 1, 2021): 1–5. http://dx.doi.org/10.31160/jotci202129a20210008.

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Penetrating injuries to the heart are usually devastating and few patients survive the initial trauma. The most frequent penetrating injuries are caused by projectile injuries and less commonly by melee weapons. Most of these injuries involve chamber free walls and a small percentage can affect the interventricular septum. We report a case in which an emergency surgical procedure was successful in controlling cardiac tamponade, and repairing a right ventricular laceration caused by multiple stab wounds. Subsequently, a successful interventional occlusion of a large interventricular septal defe
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6

Lepp??niemi, Ari K., and Norman M. Rich. "Treatment of Vascular Injuries in War Wounds of the Extremities." Techniques in Orthopaedics 10, no. 3 (1995): 265–71. http://dx.doi.org/10.1097/00013611-199501030-00019.

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7

Amarantov, D. G., M. F. Zarivchatskii, A. A. Kholodar, O. S. Gudkov, and E. V. Kolyshova. "Modern approaches to surgical treatment of thoraco-abdominal wounds." VESTNIK KHIRURGII IMENI I.I.GREKOVA 177, no. 5 (November 23, 2018): 100–104. http://dx.doi.org/10.24884/0042-4625-2018-177-5-100-104.

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Thoraco-abdominal wounds are the most severe injuries of the chest and abdomen, with mortality reaching 13–20 %. The main focus of treatment of such patients is surgical correction of the injuries. Wide range of classical and minimally invasive interventions is used for treatment of victims . The paper presents the range of views of modern researchers on the indications for laparocentesis, drainage of the pleural cavity, thoracoscopy and laparoscopy, thoracotomy and laparotomy in this pathology. The opinions of various researchers on the optimal combination of interventions and tactics of surg
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8

Trukhan, A. P., D. V. Alkhovik, I. G. Kosinsky, V. A. Koryachkin, V. A. Porkhanov, and I. Yu Zherkal. "REPUBLICAN CENTER FOR TREATMENT OF GUNSHOT WOUNDS AND MINE-EXPLOSIVE INJURIES: 3 YEARS OF EXPERIENCE AND TRENDS OF DEVELOPMENT." Novosti Khirurgii 29, no. 2 (April 21, 2021): 207–12. http://dx.doi.org/10.18484/2305-0047.2021.2.207.

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Objective. To evaluate the results of organizational measures for improving the efficiency of the Republican Center for the treatment of gunshot wounds and mine-explosive injuries. Methods. The study is based on an analysis of the work of the Republican Center for the treatment of gunshot wounds and mine-explosive injuries and includes patients (n=54) who were treated from November 1, 2016 to October 31, 2019. Gunshot wounds were detected in 42 patients (77.8%). Explosive trauma was detected in 12 patients (22.2%). The most common causes of injuries were personal carelessness (20 cases (37.0%)
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9

Jalili, Reza, Myriam Maude Verly, Breshell Russ, Ruhangiz T. Kilani, and Aziz Ghahary. "645 Topical Application of a Novel Powdered Scaffold for Rapid Treatment of Skin Injuries." Journal of Burn Care & Research 41, Supplement_1 (March 2020): S168—S169. http://dx.doi.org/10.1093/jbcr/iraa024.265.

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Abstract Introduction In large skin injuries, lack of matrix deposition impedes timely healing process. The longer a wound remains open, the greater is the risk of infection, non-healing, and other complications. It is therefore crucial to find effective means to promote rapid closure of skin defects. Our group has previously developed a liquid in situ-forming nutritional scaffold, known as MeshFill (MF). MF has been previously proven to be very effective in accelerating the wound repair process, notably that of complex wounds. However, MF is limited in its application to deep and tunnelling w
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10

Sizyi, M. Yu. "Septic complications in patients with neck wounds." Експериментальна і клінічна медицина 84, no. 3 (August 21, 2020): 64–66. http://dx.doi.org/10.35339/ekm.2019.84.03.10.

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Nowadays, we have been a steady increase in injuries as the social conditions of life and have changed. Statistically found that 54.0 % of people of car accidents have injuries to the head and neck. According to the literature, mortality in patients with neck injury which is complicating by pyoinflammatory persists up to 30.0-76.0 %. The management of neck trauma can be challenging and sometimes overwhelming, as this anatomical region contains many vital structures. These structures may pose a diagnostic and therapeutic dilemma. Our research based on the results of diagnosis and treatment of 1
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11

Stekolnikov, A. A., and M. A. Ladanova. "TECHNOLOGICAL INJURIES IN INDUSTRIAL PIG FARMING." International bulletin of Veterinary Medicine 1 (2020): 135–39. http://dx.doi.org/10.17238/issn2072-2419.2020.1.135.

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Industrial injuries in pig farms of closed type are a very common pathology. Howev-er, nowadays, injury prevention and treat-ment of sick animals in the conditions of industrial pig breeding complex do not bring good results and require improvements. Ac-cording to the literature, there is no infor-mation about the results of the use of oint-ments and immuno- stimulators in the treat-ment of pigs with bitten wounds of the ears, tails and other parts of the body. In this re-gard, we have set a goal to develop therapeu-tic measures for injuries of piglets in a pig breeding complex of a closed typ
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12

Mitkovic, Milorad, Marko Bumbasirevic, Sasa Milenkovic, Ivan Micic, Predrag Stojiljkovic, Igor Kostic, Sasa Karalejic, et al. "Nature and results of treatment of war wounds caused by cluster bombs." Acta chirurgica Iugoslavica 60, no. 2 (2013): 41–47. http://dx.doi.org/10.2298/aci1302041m.

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The aim of this study is to describe the nature of war wounds with fracture caused by cluster bombs and to suggest treatment options for such injuries. The nature of wounds caused by cluster bombs differs from those caused by conventional arms (they are more severe). The sides of the wounds are represented by conquasated soft tissues (such as fat and muscle) with thick dead tissues, ordinarily with a thickness of 0.5-4.5 cm. Another main characteristic of such injuries is the high percentage of amputations needed due to the high rate of neurovascular damage. This paper investigates the cases o
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13

Draper, David O., Kenneth L. Knight, and Justin H. Rigby. "High-Volt Pulsed Current: Treatment of Skin Wounds and Musculoskeletal Injuries." International Journal of Athletic Therapy and Training 17, no. 4 (July 2012): 32–34. http://dx.doi.org/10.1123/ijatt.17.4.32.

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14

Kornilova, A. F., and S. M. Makarova. "Prevention and modern methods of treatment of perforated eye wounds." Kazan medical journal 66, no. 2 (April 15, 1985): 94–98. http://dx.doi.org/10.17816/kazmj60730.

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Analysis of the causes of injuries at one of the factories in Saratov showed that in 92% of cases they depend on unclear instructions on safe work at the workplace, insufficient provision of work glasses of rational design.
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15

Tsymbaliuk, Vitalii I., Sergii S. Strafun, Ihor B. Tretyak, Iaroslav V. Tsymbaliuk, Alexander A. Gatskiy, Yuliia V. Tsymbaliuk, and Mykhailo M. Tatarchuk. "SURGICAL TREATMENT OF PERIPHERAL NERVES COMBAT WOUNDS OF THE EXTREMITIES." Wiadomości Lekarskie 74, no. 3 (2021): 619–24. http://dx.doi.org/10.36740/wlek202103210.

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The aim: Improving the effectiveness of patients' treatment with combat injuries of the peripheral nervous system, which consists in the application and development of new methods of reconstructive interventions, optimizing a set of therapeutic and diagnostic measures for the most effective management of this category of patients with peripheral nerve injury. Materials and methods: The research is based on the results of surgical treatment of 138 patients with combat injuries of peripheral nerves for the period from 2014 to 2020. The mean age was 33.5 ± 2.1 years. Patients were treated for 1 t
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16

ANGERMANN, P., and M. LOHMANN. "Injuries to the Hand and Wrist. A Study of 50,272 Injuries." Journal of Hand Surgery 18, no. 5 (October 1993): 642–44. http://dx.doi.org/10.1016/0266-7681(93)90024-a.

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This study reports the causes, characteristics and treatment of injuries to the hand and wrist presented to five accident and emergency departments in a 2-year survey of 13% of the Danish population. The rate of injury to the hand or wrist was 28.6% of all injuries, or 3.7 per 100,000 inhabitants per year. 34% of the accidents were domestic, 35% were leisure accidents, 26% were occupational and 5% were traffic accidents. Only 2% of the patients were admitted to hospital for further treatment or observation and 13% were referred to a hospital as outpatients. The most frequent causes for admissi
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17

Kočišová, A., J. Pistl, R. Link, E. Čonková, and M. Goldová. "Maggot Debridement Therapy in the Treatment of Footrot and Foot Scald in Sheep." Acta Veterinaria Brno 75, no. 2 (2006): 277–81. http://dx.doi.org/10.2754/avb200675020277.

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In sheep with acute and chronic interdigital skin inflammation, maggot therapy was used for the debridement and speeding up the healing process. Sheep were housed at the university farm Zemplínska Teplica and before using maggot therapy, they were unsuccessfully treated by a footbath containing 10% copper sulphate and topical application of oxytetracycline solution in alcohol. Six non-pregnant Valachian sheep between two to four years of age, weighing 43 to 57 kg were treated with maggots of Lucilia sericata (Meigen) (Diptera: Calliphoridae). The larval population should be 8-12 per square cen
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18

Bajec, Djordje, Dejan Radenkovic, Pavle Gregoric, Vasilije Jeremic, Vladimir Djukic, Nenad Ivancevic, Borivoje Karadzic, et al. "Hirursko lecenje povreda jetre - petogodisnje iskustvo." Acta chirurgica Iugoslavica 57, no. 4 (2010): 9–14. http://dx.doi.org/10.2298/aci1004009b.

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Due to improved methods of treatment and management of hemorrhage, the mortality from liver injuries has decreased significantly over the past few decades. In spite of that, liver injuries still represent diagnostic and therapeutic challenge. This retrospective study included 197 patients surgically treated because of trauma of the liver at The Clinic for Emergency Surgery, during the period 2004-2009. The results showed significant difference in mortality rates in cases of penetrating wounds compared to blunt trauma and gunshot wounds. The severity of injury evaluated by Organ Injury Scale wa
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19

Cole, Roger D., J. Dale Browne, and C. David Phipps. "Gunshot Wounds to the Mandible and Midface: Evaluation, Treatment, and Avoidance of Complications." Otolaryngology–Head and Neck Surgery 111, no. 6 (December 1994): 739–45. http://dx.doi.org/10.1177/019459989411100607.

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As American society becomes progressively violent, an ever-increasing number of gunshot wounds are being seen across the United States. Particularly challenging are injuries that involve the mandible and midface, not only because of problems with reconstructing bone and soft-tissue defects but also because of emergent problems with airway obstruction and neurovascular compromise. We present 40 cases of gunshot wounds to the mouth, mandible, and maxilla treated at Wake Forest University Medical Center during the past 7 years. The focus of this retrospective analysis is on emergency evaluation a
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20

Dhupa, S., and J. E. Harris. "Treatment of degloving injuries with autogenous full thickness mesh scrotal free grafts." Veterinary and Comparative Orthopaedics and Traumatology 21, no. 04 (2008): 378–81. http://dx.doi.org/10.3415/vcot-07-04-0029.

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SummaryIn this report, we evaluated the effectiveness of scrotal tissue as an autogenous free skin graft to treat cutaneous degloving injuries of the distal limb in dogs. Surgery was performed on two male intact dogs with distal extremity degloving wounds. Dog #1 had a tarsal degloving wound with exposure of the distal tibial and tarsal bones. Dog #2 had a degloving injury over the metacarpals. Wounds were treated with daily wetto- dry bandages in order to develop a healthy bed of granulation tissue at the graft recipient site. Scrotal ablation castration was performed once the recipient site
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21

Hanazono, Yutaka, Hiroaki Shibata, Naohide Ageyama, Yujiro Tanaka, Yukiko Kishi, Shinichiro Nakamura, Kyoko Sasaki, Satoshi Hayashi, Yoshihiro Kitano, and Keiji Terao. "Prevention of Tumor Formation after Allogeneic In Utero Transplantation of Cynomolgus Monkey Embryonic Stem Cell-Derived Hematopoietic Precursors." Blood 106, no. 11 (November 16, 2005): 189. http://dx.doi.org/10.1182/blood.v106.11.189.189.

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Abstract Although human ES cell-based transplantation therapies would hold a great potential in the treatment of a variety of diseases and injuries, there is a concern for teratoma formation after transplantation. In this study, we assessed the risk of tumor formation during the hematopoietic engraftment derived from cynomolgus ES cells (cyESCs) in an allogeneic transplantation model. cyESCs expressing GFP were cultured on OP9 stromal cells and induced to differentiate into the putative hematopoietic precursors. According to the flow cytometric analysis, CD34 was up-regulated on day 6 but decr
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22

Yamamoto, Ryo, Mark Muir, and Alicia Logue. "Colon Trauma: Evidence-Based Practices." Clinics in Colon and Rectal Surgery 31, no. 01 (December 19, 2017): 011–16. http://dx.doi.org/10.1055/s-0037-1602175.

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AbstractColon injury is not uncommon and occurs in about a half of patients with penetrating hollow viscus injuries. Despite major advances in the operative management of penetrating colon wounds, there remains discussion regarding the appropriate treatment of destructive colon injuries, with a significant amount of scientific evidence supporting segmental resection with primary anastomosis in most patients without comorbidities or large transfusion requirement. Although literature is sparse concerning the management of blunt colon injuries, some studies have shown operative decision based on
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23

Jha, Shilpa, Wasim S. Khan, and Nashat A. Siddiqui. "Mammalian Bite Injuries to the Hand and Their Management." Open Orthopaedics Journal 8, no. 1 (June 27, 2014): 194–98. http://dx.doi.org/10.2174/1874325001408010194.

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Bite wounds are a common form of hand injury with the potential to lead to severe local and systemic sequelae and permanent functional impairment. Mammalian bite wounds may be caused by a variety of animal class and species; injuries resulting from dogs, cats and humans are the most widely discussed and reported in the literature. Bite wounds may be contaminated with aggressive pathogens and the anatomical vulnerability of structures within the hand means that without early recognition and treatment with irrigation and antibiotics, alongside a low index of suspicion for deep structural involve
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24

Lentscher, Jessica A., Joshua C. Combs, Karrie Walker, Christopher M. Young, and Rebecca Chason. "Postdeployment Fertility Challenges and Treatment in the Modern Era." Seminars in Reproductive Medicine 37, no. 05/06 (September 2019): 239–45. http://dx.doi.org/10.1055/s-0040-1713430.

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AbstractCurrent war-fighting environments have shifted dramatically over the past decade, and with this change, new types of injuries are afflicting American soldiers. Operative Enduring Freedom and Operation Iraqi Freedom have noted an increased use of sophisticated improvised explosive devices by adversaries. Injuries not frequently seen in previous conflict are dismounted complex blast injuries, which involve multiple proximal amputations, pelvic fractures, and extensive perineal wounds. Thus, an unforeseen consequence of the decreased mortality rate after these complex blast injuries is a
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25

de Wind, Christina M. "Severe Infections following Fish Bone and Spine Injuries." Tropical Doctor 26, no. 4 (October 1996): 168–69. http://dx.doi.org/10.1177/004947559602600410.

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Injuries by fish bones and spines can cause severe infections and tissue necrosis, more extensive than one would expect in such small wounds. This paper describes the injuries and the treatment of 25 patients.
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26

Syzyi, M. Yu. "URGICAL TACTICS IN WOUNDS OF PHARYNX AND CERVICAL ESOPHAGUS." Kharkiv Surgical School, no. 5-6 (December 25, 2019): 95–98. http://dx.doi.org/10.37699/2308-7005.5-6.2019.20.

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Summary. The results of surgical treatment of 98 patients with penetrating injuries to the pharynx and cervical esophagus are presented. The patients were divided into the main and the comparison group. In the comparison group, the traditional principles of intervention were used. In the main group, surgical intervention was performed with a mini access on the neck 3-4 cm in length using a ring-shaped retractor. In the main group there was a twofold decrease in the frequency of purulent complications after surgical treatment of penetrating injuries to the pharynx and cervical esophagus, in com
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27

Kotiv, B. N., I. M. Samokhvalov, V. Yu Markevich, A. P. Chuprina, I. I. Dzidzava, O. V. Barinov, V. V. Suvorov, A. V. Goncharov, A. A. Rud, and K. V. Petukhov. "Prevention and treatment of infectious complications of penetrating thoracic injuries." Bulletin of the Russian Military Medical Academy 20, no. 4 (December 15, 2018): 22–25. http://dx.doi.org/10.17816/brmma12240.

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Results of treatment of 325 wounded are analyzed with penetrating wounds of the chest and identify risk factors for the development of infectious complications. Found that infectious complications of the chest organs developed in 49 (15,1%) cases. It has been established that the most frequent infectious complications of penetrating wounds of the chest are post-traumatic pneumonia (67,3% of cases) and acute empyema of the pleura (26,5% of cases). The most prognostic significant risk factors for the development of infectious complications were identified: the type of injury (odds ratio - 2,48;9
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Syzyi, M. Yu. "TREATMENT-DIAGNOSTIC MEASURES FOR INJURY OF THE NECK." Kharkiv Surgical School, no. 3-4 (December 20, 2019): 123–25. http://dx.doi.org/10.37699/2308-7005.3-4.2019.28.

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Summary. The article is devoted to the study of the urgent problem of neck injury and medical diagnostic tactics. Externally, a small wound on the neck can hide serious damage to deep structures and adjacent anatomical areas. In peacetime during neck injuries, it is necessary stick to the basic principles of surgery: all wounds are subject to primary surgical treatment with a thorough revision of the wound canal. The algorithm of therapeutic and diagnostic measures depends on the nature and severity of the damage, clinical symptoms, and related injuries that are life-threatening.
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Zarutskii, Yaroslav, S. A. Aslanyan, I. B. Plis, A. O. Kompaniiets, and V. S. Goncharuk. "Application of NPWT in the surgical treatment of wounds and injuries of various locations - case series." Negative Pressure Wound Therapy Journal 5, no. 3 (September 28, 2018): 10. http://dx.doi.org/10.18487/npwtj.v5i3.44.

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In the modern world, local military conflicts are not uncommon. A feature of local wars is a dynamically changing tactical situation, which can lead to massive losses and more serious injuries. This creates new challenges related to the treatment of combat trauma victims. We analyzed our experience of application of NPWT in complex surgical treatment of combat wounds and injuries of various locations.
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30

Syre, Peter, Leonardo Rodriguez-Cruz, Rajiv Desai, Karl A. Greene, Robert Hurst, James Schuster, Neil R. Malhotra, and Paul Marcotte. "Civilian gunshot wounds to the atlantoaxial spine: a report of 10 cases treated using a multidisciplinary approach." Journal of Neurosurgery: Spine 19, no. 6 (December 2013): 759–66. http://dx.doi.org/10.3171/2013.8.spine12907.

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Object Gunshot wounds to the atlantoaxial spine are uncommon injuries and rarely require treatment, as a bullet traversing this segment often results in a fatal injury. Additionally, these injuries are typically biomechanically stable. The authors report a series of 10 patients with gunshot wounds involving the lateral mass and/or bodies of the atlantoaxial complex. Their care is discussed and conclusions are drawn from these cases to identify the optimal treatment for these injuries. Methods A retrospective review was conducted of patients presenting to the emergency rooms of 3 institutions w
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31

Wade, Katherine Jane. "The sword and the knife: a comparison of ancient Egyptian treatment of sword injuries and present day knife trauma." Res Medica 24, no. 1 (December 31, 2017): 47–56. http://dx.doi.org/10.2218/resmedica.v24i1.1494.

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The Edwin Smith papyrus is the oldest known surgical treatise, thought to have been written in 1700 B.C. It was first discovered in Luxor in 1862 and was first translated from hieroglyph script by Egyptologist, James Henry Breasted in 1930. The papyrus details forty eight traumatic injuries which are topographically organised and considered formulaically through examination, diagnosis, prognosis and treatment.The Khopesh was an ancient Egyptian sickle shaped sword which was thought to have been used to inflict a slash-type sharp force injury during battle. Treatment of these slash-type wounds
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32

Langford, Jane H., Phillip Artemi, and Shalom I. Benrimoj. "Topical Antimicrobial Prophylaxis in Minor Wounds." Annals of Pharmacotherapy 31, no. 5 (May 1997): 559–63. http://dx.doi.org/10.1177/106002809703100506.

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OBJECTIVE: To evaluate the ability of a novel topical antimicrobial gel containing cetrimide, bacitracin, and polymyxin B sulfate to prevent infections of minor wounds. DESIGN: A clinical trial compared the test preparation with placebo and a povidone iodine antiseptic cream. SETTING: Five primary schools in Sydney, Australia, participated in the study over a 6-week spring/summer school term. SUBJECTS: Children aged 5–12 years with parental consent were eligible for study participation. Accidental injuries occurring at school were treated in a standardized manner by nurses at each site. OUTCOM
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33

Weiss, Janet M. "Treatment of Leg Edema and Wounds in a Patient With Severe Musculoskeletal Injuries." Physical Therapy 78, no. 10 (October 1, 1998): 1104–13. http://dx.doi.org/10.1093/ptj/78.10.1104.

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34

Johnson, F. E., Y. Wang, T. Ling, S. Chuang, S. S. Huang, and J. S. Huang. "Synthetic TGF-ß antagonist promotes healing of injured epithelial surfaces." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 18586. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.18586.

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18586 Background: Cancer treatment often results in injury to epithelial surfaces. These injuries are often symptomatic and can delay or prevent further treatment. Since transforming growth factor-1 (TGF-ß) mediates inflammation, fibrosis, and epithelial mitogenesis, agents modulating TGF-ß may be useful in treating such wounds. We synthesized a dodecapeptide containing the active site of human TGF-ß. It is a TGF-ß antagonist in vitro. We investigated whether application to cutaneous wounds might promote epithelialization and decrease scarring by directly blocking local TGF-ß activity. Methods
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Smaropoulos, Eleftherios, and Niels AJ Cremers. "Medical grade honey for the treatment of paediatric abdominal wounds: a case series." Journal of Wound Care 29, no. 2 (February 2, 2020): 94–99. http://dx.doi.org/10.12968/jowc.2020.29.2.94.

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Objective: Children are at high risk of injuries and wounds. The application of medical grade honey is a promising approach to improving the healing of wounds of various origin and severity. However, the use of medical grade honey in young paediatric patients remains limited. The aim of this study is to show the safety, efficacy and usefulness of medical grade honey in abdominal wounds, of different causes, in paediatric patients. Method: This was a prospective, observational case series evaluating five young infants with abdominal wounds at the General Hospital in Thessaloniki. All wounds wer
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Samokhvalov, I. M., K. P. Golovko, V. V. Boyarintsev, V. I. Badalov, T. Yu Suprun, A. M. Nosov, A. B. Vertiy, V. V. Denisenko, V. A. Chupriaev, and M. S. Grishin. "Concept formulation for the early-stage pathogenetic treatment of the severe injuries and traumas." Bulletin of the Russian Military Medical Academy 22, no. 3 (December 15, 2020): 23–28. http://dx.doi.org/10.17816/brmma50526.

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Abstract. 451 lethal outcomes of 5581 casualties with gunshot wounds occurring at the medical treatment facilities have been analyzed. Total lethality rate was 8,1%. Lethal outcome time varied from 1 to 19 days (10,61,9). 50,3% of casualties died during the advanced trauma management (Role 2), 17,3% at the Role 3 hospitals, 32,4% at the Role 4 hospitals. The predominant injury localization causing death was abdominal wounds 34,8%, and head injuries 23,1%. The main cause of death of wounds casualties arriving at the medical treatment facilities was life-threatening injury consequences (34,8%) a
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Dutta, Anupam, Taniya Sarkar Dutta, Anup Kumar Das, and Pranoy Dey. "Haemostatic action of a topical foam-based patch (VELSEAL-T) in haemophiliac patients with external bleeding." Journal of Haemophilia Practice 7, no. 1 (June 17, 2020): 78–84. http://dx.doi.org/10.17225/jhp00160.

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AbstractIntroductionHaemophilia is an X-linked congenital bleeding disorder due to deficiency of coagulation factor VIII (in haemophilia A) or factor IX (in haemophilia B) caused by mutations of the respective clotting factor genes. Treatment involves the administration of an appropriate dose of factor concentrate, as soon as possible, in the event of any bleeding episode. In low-resource settings, such as Northeast India, where factor concentrates are not widely available, people with haemophilia (PwH) may bleed profusely even from trivial external injuries, warranting transfusion of blood or
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Widhyari, Sus Derthi, Ietje Wientarsih, Aulia Andi Mustika, April Hari Wardhana, Dodi Darmakusuma, Lina Noviyanti Sutardi, and Muhammad Bintang. "Potensi Salep Ekstrak Daun Sirih Merah Terhadap Profil Eritrogram Sebagai Terapi pada Luka Miasis (THE EFFECT OF RED BETEL LEAF EXTRACT OINTMENT IN ERYTHROGRAM PROFILES AS THERAPY IN MYASIS WOUND)." Jurnal Veteriner 19, no. 1 (June 26, 2018): 30. http://dx.doi.org/10.19087/jveteriner.2018.19.1.30.

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The objectives of this research was to examine the efficacy of red betel extract ointment to eritrogram profiles in infected sheep myiasis. Fifteen female sheeps were divided into five treatments, which were sheep without wound, treated with asuntol 2%, without any treatment,with red betel leaf extract ointment 2% and 4 %. Three incision wounds were made on the sheep’s back, 50 larvae given to every wounds to four treatment, except the healthy sheep (K). Blood was taken on the 0, 3th and 7th to determine erythrocytes counts, hematocrit values (PCV) and hemoglobin levels (Hb). The result showed
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KULCHESKI, ÁLYNSON LAROCCA, XAVIER SOLER I. GRAELLS, ANDRÉ LUÍS SEBBEN, MARCEL LUIZ BENATO, and PEDRO GREIN DEL SANTORO. "MANAGEMENT OF SPINAL GUNSHOT WOUND INJURIES." Coluna/Columna 20, no. 3 (September 2021): 217–23. http://dx.doi.org/10.1590/s1808-185120212003242926.

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ABSTRACT Objectives Elaborate a care protocol for spinal gunshot wounds (GSWs), based on the experience of more than fifteen years of treating this type of injury. Methods A retrospective cross-sectional analysis of the electronic medical record data of a tertiary hospital related to the treatment of spinal GSWs between January 2002 and January 2018. Results The management proposed was applied to 700 patients. Epidemiological data collected describes the population served. Conclusions An easy-to-use treatment flowchart was developed that, according to factors related to the neurological condit
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Galili, Uri. "Acceleration of Wound Healing byα-gal Nanoparticles Interacting with the Natural Anti-Gal Antibody". Journal of Immunology Research 2015 (2015): 1–13. http://dx.doi.org/10.1155/2015/589648.

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Application ofα-gal nanoparticles to wounds and burns induces accelerated healing by harnessing the natural anti-Gal antibody which constitutes ~1% of human immunoglobulins.α-gal nanoparticles present multipleα-gal epitopes (Galα1-3Galβ1-4GlcNAc-R), the carbohydrate ligand of anti-Gal. Studiedα-gal nanoparticles were comprised of glycolipids withα-gal epitopes, phospholipids, and cholesterol. Binding of anti-Gal toα-gal nanoparticles in wounds activates the complement cascade, resulting in formation of chemotactic complement cleavage peptides that induce rapid recruitment of many macrophages.
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Abdurakhmonov, Farkhod Rakhmonovich, Jasur Alimdjanovich Rizayev, and Shukhrat Abdujajilovich Boymurodov. "Assessment Of The Consequences Of The Ozone For The Treatment Of The Soft Tissue Injuries Of The Maxillofacial Area." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 06 (June 10, 2021): 75–81. http://dx.doi.org/10.37547/tajmspr/volume03issue06-12.

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As it is clear that wounds of the maxillofacial area are much more different from other parts of the body. Due to the importance of its function and cosmetic value combined soft tissue lesions occupy a special position in human bones and tissues. In this article certain valuable information is shown about ozone’s physical, chemical compositions and its positive effect on the recovery of the combined soft tissue wounds located in the facial region. To evaluate the effectiveness of ozone for the treatment of soft tissue wounds of maxillofacial injuries overall 60 patients investigated [1,2]. As
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Miller, Keith R., Matthew V. Benns, Matthew C. Bozeman, Glen A. Franklin, Briang Harbrecht, Nicholas A. Nash, Jason W. Smith, William S. Smock, and J. David Richardson. "Operative Management of Thoracic Gunshot Wounds: More Aggressive Treatment Has Been Required over Time." American Surgeon 85, no. 11 (November 2019): 1205–8. http://dx.doi.org/10.1177/000313481908501123.

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Our department has a database of thoracic gunshot wounds (GSWs), which has cataloged these injury patterns over the past five decades. Prevailing wisdom on the management of these injuries suggested operative treatment beyond tube thoracostomy is not commonly required. It was our clinical impression that the operative treatment required beyond chest tube placement has greatly increased over the past several decades, whereas the operative management of cardiac GSWs seemed to be increasingly infrequent events. To test these observations, we analyzed the treatment of GSWs to the chest and heart i
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Madigan, J., J. Rowe, J. Angelos, W. F. Herthel, D. Matz, M. Dinucci, and V. Fletcher. "(A323) Wildfire Associated Burn Injury of 1400 Sheep in Northern California: A Coordinated Mass Casualty Veterinary Response." Prehospital and Disaster Medicine 26, S1 (May 2011): s90—s91. http://dx.doi.org/10.1017/s1049023x11003074.

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IntroductionWildfires can injure animals both from burns and inhalation of smoke and particulates. In 2006 a rapidly moving grass wildfire burned 12 square miles in Yolo County. Approximately 1400 sheep on the range suffered variable degrees of burns. A coordinated effort of triage and individual treatment or humane euthanasia was performed by the UC Davis Veterinary Emergency Response Team.MethodsAnimals: Two sheep ranches with 1100 (ranch A) and 300 (ranch b) adult sheep of different breeds, ranging in age from 1-6 years of age. Initial owner evaluation: Both ranchers considered humane destr
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44

Carter, Jeffrey E., James H. Holmes, Kevin N. Foster, David J. Smith, and Jeffrey W. Shupp. "537 Autologous Skin Cell Suspension for the Treatment of Small (≤10% TBSA) Mixed-Depth Burns." Journal of Burn Care & Research 42, Supplement_1 (April 1, 2021): S116—S117. http://dx.doi.org/10.1093/jbcr/irab032.187.

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Abstract Introduction Split-thickness skin grafts (STSGs) have been the standard of care for many decades. Despite their widespread use, STSGs frequently fail. Autologous skin cell suspension (ASCS) is an FDA approved point of care regenerative medicine technology that reduces donor skin requirements without compromising clinical outcomes. ASCS allows for early treatment and less donor skin harvested that may be useful for hard-to-treat anatomical locations, in compromised patients that have risks for impaired wound healing, or elderly patients with thinner skin. We examined ASCS treatment as
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45

Piccart, Frederik, JakobTitiaan Dormaar, Ruxandra Coropciuc, Joseph Schoenaers, Michel Bila, and Constantinus Politis. "Dog Bite Injuries in the Head and Neck Region: A 20-Year Review." Craniomaxillofacial Trauma & Reconstruction 12, no. 3 (September 2019): 199–204. http://dx.doi.org/10.1055/s-0038-1660441.

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Dog bite-related wounds seem to have become a common problem, especially when they relate to the head and neck region. According to Overall and Love, up to 18 per 1,000 people sustain a dog bite every year, of whom 3 need medical attention. Approximately 1 to 2% of bite injuries require hospitalization of the victims. Most of the lacerations are found in the upper lip and the nose regions and they are classified according to severity and concomitant damage to other organs. Bite wounds are considered “dirty” wounds and are prone to infection. When dealing with bite wounds, there is always an in
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46

Kotiv, B. N., I. M. Samokhvalov, V. Ju Markevich, I. I. Dzidzava, O. V. Barinov, V. V. Suvorov, A. V. Goncharov, and K. V. Petukhov. "Thoracoabdominal stab wounds: modern surgical tactics." Grekov's Bulletin of Surgery 178, no. 1 (March 28, 2019): 34–38. http://dx.doi.org/10.24884/0042-4625-2019-178-1-34-38.

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Theobjectivewas to determine the optimal therapeutic and diagnostic algorithm for thoracoabdominal injury.Material and methods. The results of the examination and treatment of 389 injured patients with combined stab wounds of chest and abdomen were analyzed. The injuries were thoracoabdominal in 54 (13.9 %) cases.Results. We analyzed instrumental invasive and non-invasive diagnostic methods. The sequence of surgical interventions was determined.Conclusion. We revealed that the correct sequence and volume of surgical intervention ensured the success of treating the injured patients, while in ca
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Danchyn, A. O., O. M. Goncharuk, S. A. Usatov, M. S. Altabury, and G. O. Danchyn. "Biophysical mechanisms of the formation of wound channels in non-penetrating gunshot craniocerebral wounds." Ukrainian Interventional Neuroradiology and Surgery 35, no. 1 (June 30, 2021): 33–42. http://dx.doi.org/10.26683/2786-4855-2021-1(35)-33-42.

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Objective ‒ to develop recommendations for optimization of primary surgical treatment of gunshot penetrating craniocerebral wounds on the basis of theoretical and applied study of one of the sections of wound ballistics ‒ biophysical mechanisms of wound canal formation, concomitant impenetrable wounds and intracranial injuries.Materials and methods. The medical histories of 155 wounded who received a non-pe-netrating craniocerebral injury during the hostilities in the East of Ukraine in 2014‒2020 were studied. All of the wounded were males between 18 and 60 years old (mean age ‒ 35.1 years). T
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48

Irfan-maqsood, Muhammad. "Classification of Wounds: Know before Research and Clinical Practice." Journal of Genes and Cells 4 (January 15, 2018): 1. http://dx.doi.org/10.15562/gnc.61.

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Cutaneous wounds are known as the damages and injuries on the skin. Knowing the type of wound is very important before any kind of treatment or therapy being applied. Each type of wound is different from other due to the different structure, biology and pathophysiology, therefore, a kind of treatment for one wound cannot be specified for others. Considering the importance of types of wounds, these wounds are classified into different categories because of their different pathobiology. This manuscript would be a great piece of knowledge for the tissue engineer to develop specific skin substitut
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49

Lihonenko, О. V., О. V. Storozhenko, А. B. Zubakha, І. А. Shumeiko, and І. О. Chorna. "Complex treatment of experimental purulent wound of soft tissues." Klinicheskaia khirurgiia 87, no. 7-8 (September 30, 2020): 58–62. http://dx.doi.org/10.26779/2522-1396.2020.7-8.58.

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Objective. To study the impact of estrogens and liposomes on course of healing process in purulent wounds of soft tissues in experiment.
 Маterials and methods. Еxperimental investigation was done on 21 sheep. In the laboratory animals purulent-inflammatory process was simulated. Тhe laboratory animals were distributed into two groups: a control - 6 sheep and investigated - 15. All the animals obtained conventional therapy. In laboratory animals of the investigated group estrogens and liposomes were added to complex of the conventional treatment measures. The healing process course was co
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50

Tkachenko, Pavlo I., Serhii O. Bilokon, Olha B. Dolenko, Nataliia M. Korotych, Yuliia V. Popelo, and Nataliia P. Bilokon. "BITTEN WOUNDS OF THE MAXILLOFACIAL AREA IN CHILDREN." Wiadomości Lekarskie 73, no. 6 (2020): 1108–13. http://dx.doi.org/10.36740/wlek202006105.

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The aim of the work is to determine the frequency, structure, features of clinical manifestations and treatment of bitten wounds of the face and neck in children of Poltava region. Materials and methods: It has been analyzed 91 histories of disease of thematic patients undergone treatment at the Surgical Department of Pediatric town clinical hospital of Poltava. Results: In the structure of traumatic injuries of maxillofacial area in children 5.3% were patients with bitten wounds of the face and neck. Among the injured were children of the age 7-12 years old (30.2%). In 74.7% of cases, the bit
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