Literatura académica sobre el tema "Shi pin wei sheng"

Abstract Background: Morpho-physiological alternations of platelets provided a rationale to harness RNA sequencing of tumor-educated platelets (TEPs) for preoperative diagnosis of cancer. Timely, accurate, and non-invasive detection of ovarian cancer in women with adnexal masses presents a significant clinical challenge. Patients and Methods: This intercontinental, hospital-based, diagnostic study included 761 treatment-naïve inpatients with histologically confirmed adnexal masses and 167 healthy controls from nine medical centers (China, n=3; Netherlands, n=5; Poland, n=1) between September 2016 and May 2019. The main outcomes were the performance of TEPs and their combination with CA125 in two Chinese (VC1 and VC2) and the European (VC3) validation cohorts collectively and independently. Exploratory outcome was the value of TEPs in public pan-cancer platelet transcriptome datasets. Results: The AUCs for TEPs in the combined validation cohort, VC1, VC2, and VC3 were 0.918 (95% CI 0.889-0.948), 0.923 (0.855-0.990), 0.918 (0.872-0.963), and 0.887 (0.813-0.960), respectively. Combination of TEPs and CA125 demonstrated an AUC of 0.922 (0.889-0.955) in the combined validation cohort; 0.955 (0.912-0.997) in VC1; 0.939 (0.901-0.977) in VC2; 0.917 (0.824-1.000) in VC3. For subgroup analysis, TEPs exhibited an AUC of 0.858, 0.859, and 0.920 to detect early-stage, borderline, non-epithelial diseases and 0.899 to discriminate ovarian cancer from endometriosis. Analysis of public datasets suggested that TEPs had potential to detect multiple malignancies (Table 1). Conclusions: TEPs had robustness, compatibility, and universality for preoperative diagnosis of ovarian cancer since it withstood validations in populations of different ethnicities, heterogeneous histological subtypes, early-stage ovarian cancer as well as other malignancies. However, these observations warrant prospective validations in a larger population before clinical utilities. Table 1. Performance for TEPs in public pan-cancer datasets. Disease n Healthy Control AUC, area under the curve (95% CI) Women NSCLC (non-small-cell lung cancer) 126 77 0.758 (0.691-0.825) Breast cancer 38 77 0.817 (0.726-0.909) Colorectal cancer 18 77 0.973 (0.945-1.000) Pancreatic cancer 16 77 0.993 (0.981-1.000) Glioblastoma 10 77 0.923 (0.831-1.000) Men NSCLC 119 82 0.746 (0.677-0.815) Colorectal cancer 25 82 0.933 (0.884-0.982) Pancreatic cancer 22 82 0.993 (0.984-1.000) Glioblastoma 19 82 0.981 (0.959-1.000) All NSCLC 245 159 0.774 (0.728-0.820) Colorectal cancer 40 159 0.978 (0.961-0.996) Breast cancer 38 159 0.821 (0.736-0.906) Pancreatic cancer 35 159 0.987 (0.974-0.999) Glioblastoma 35 159 0.931 (0.890-0.972) Hepatobiliary carcinomas 14 159 0.991 (0.978-1.000) Citation Format: Yue Gao, Chun-Jie Liu, Hua-Yi Li, Xiao-Ming Xiong, Sjors G.j.g. In ‘t Veld, Gui-Ling Li, Jia-Hao Liu, Guang-Yao Cai, Gui-Yan Xie, Shao-Qing Zeng, Yuan Wu, Jian-Hua Chi, Qiong Zhang, Xiao-Fei Jiao, Lin-Li Shi, Wan-Rong Lu, Wei-Guo Lv, Xing-Sheng Yang, Jurgen M.j. Piek, Cornelis D de Kroon, C.a.r. Lok, Anna Supernat, Sylwia Łapińska-Szumczyk, Anna Łojkowska, Anna J. Żaczek, Jacek Jassem, Bakhos A. Tannous, Nik Sol, Edward Post, Myron G. Best, Bei-Hua Kong, Xing Xie, Ding Ma, Thomas Wurdinger, An-Yuan Guo, Qing-Lei Gao. Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr LB168.

ABSTRACTThe basic error in Hu Shi's “An Exposition on Confucians” lay in discussing the basic nature of the Confucian school on the basis of the “tragic fate and miserable status of the survivors of the Shang”; for half a century this mistaken premise has been accepted by most historians as proven. On the basis of an analysis of pre-Qin literary sources, this paper first proves that there was no “tragedy of the defeated state”; on the contrary, the Yin survivors continued to possess considerable political power and quite high social status. Second, on the basis of newly un earthed Shang and Zhou inscriptions, the fate and status of the Shang survivors is set forth from three sides: (1) The history of the Wei Shi clan and Lu Sheng clan of the Guanzhong region, for which genealogies of seven-eight or six-seven generations exist, is reconstructed on the basis of, for the former, the Ding bronze horde newly unearthed from Fufeng Zhuangbai, and, for the latter, the inscriptions on already known as well as recently unearthed bronze vessels from the same area. Both clans were survivors from the Shang and close relatives of the Shang king; they possessed cities, subjects, and official positions, as well as holding offices in charge of troops. (2) The same conclusion may be reached in individual cases in various other kingdoms, such as for Mo Situ Sung of the state of Wei , and Dong Hefu of the state of Yan . As for the Ling Shi , Chen Chen and Deng of Cheng Zhou , Cheng Zhou is the ancient home of the Shang survivors, yet they seem not to have been the object of any special restriction or suppression. This section is based solely on inscriptions; the conclusions reached, however, are completely in agreement with those derived from literary evidence in the previous section. Finally an attempt is made to explain why the survivors of the Shang had land, subjects, offices, and power. We believe that it was due to a political and social structure with the clan as the primary unit. A complete explication of this question awaits a detailed study of oracle-bone and archaeological source material.

Исследована адсорбция аниона серина на гладком Pt и Pt(Pt)-электроде. Методом кривых заряжения получены стационарные и кинетические изотермы адсорбции. Установлено, что как на гладком, так и Pt(Pt)-электроде, кинетика исследуемых процессов подчиняется уравнению Рогинского-Зельдовича, а стационарное заполнение описывается изотермой Темкина. При этом адсорбция аниона серина на Pt(Pt) сопровождается диссоциацией адсорбата. Найдены основные термодинамические характеристики (константа адсорбционного и изменение свободной энергии Гиббса) процесса адсорбции аниона серина на обоих электродах. ЛИТЕРАТУРА Damaskin B., Petrii A. O., and Batrakar V.Adsorption of Organic Compounds on Electrodes. Plenum Press, New York, 1973. Sobkowski J., Juzkiewics-Herbish M. Metall/Solution Interface: an Experimental Approach, Modern Aspects of Electrochemistry, no. 31. Eds. by J. O¢ Bockris, R. E. White and B. E. Conway. Plenum Press, New York, London, 1997, p. 1. Frumkin A. N. 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Šiame straipsnyje tyrinėjama klasikinio daoizmo pagrindėjų - Laozi ir Zhuangzi - idėjų transformacija įtakingoje Kinijos menininkų intelektualų (wenrenhua) estetikoje. Darbas pagrįstas autentiškais šaltiniais (klasikinio daoizmo tekstais - “Laozi”, “Zhuangzi” bei tapybos teorijos ir estetikos veikalais - Gu Kaizhi “Lun hua”(“Apie tapybą”), “Hua Yuntaishan ji” (“Užrašai apie tai, kaip tapyti Debesų terasos kalną”), Zong Bingo “Hua shanshui xu” (“Įvadas į peizažinę tapybą”), Wang Wei (415-145) “Xu hua” (“Įvadas į tapybą”), Xie He “Guhua pinlu” (“Senosios tapybos principai”), Wang Wei (701-769) “Shanshui jue” (“Peizažinės tapybos paslaptys”), “Shanshui lun” (“Apie peizažinę tapybą”, Shi Tao “Kugua heshang hualu” (“Vienuolio, vardu Kartus Moliūgas, pasakojimai apie tapybą”), Su Shi, Mi Fu, Ni Zanio, Zhao Mengfu, Dong Qichango ir kt. traktatais. Remiantis daoistiniais filosofiniais-estetiniais principais (Dao, qi (gyvybinė energija), ziran (spontaniškumas, savaimingumas), pu (pirminis paprastumas), xu (tuštumas) ir kt.) bei pamatinėmis menininkų intelektualų estetikos kategorijomis (shen (dvasia), yi (idėja-mintis), qi (gyvybinė energija), ziran (spontaniškumas, savaimingumas), pu (pirminis paprastumas), sheng (gyvybė, gyvybingumas) bei jų deriniais - zhuan shen, shenqi, shengqi ir kt.) atskleidiama, kaip Laozi ir Zhuangzi idėjos iš esmės nulėmė visą tolesnę wenrenhua estetikos sklaidą.

Structural reinvestigations of the Cu7Sn3S10 sample prepared in the reported conditions show that the phase of interest is not tetragonal, but crystallizes in the cubic symmetry. This imposes a re-interpretation of the thermoelectric properties in this system.

Although the sodium hypochlorite (NaOCl) solution has been part of the endodontic arsenal for more than one century, current investigations have been unable to determine which NaOCl volume and concentration or which time of application are able to dissolve organic matter without weakening the dental structure during the phase of biomechanical preparation of the root canal. Thus, the objective of the present study was to conduct a systematic literature review with no restriction of publication year or language in order to resolve these questions. The search strategy included the following databases: PubMed, LILACS, Web of Science and ClinicalTrials.gov, and only in vivo human clinical trials were included in the final review. After the removal of duplicates, the systematic literature review yielded 3,717 articles. Of these, 3,685 were excluded after applying the exclusion criteria (ex vivo studies, animal studies, cell-culture studies, narrative review, and studies with no available full texts). A total of 32 full-text articles were assessed for eligibility. After evaluating the full text, all articles were excluded for different reasons. No studies fulfilled our inclusion criteria. This review was unable to answer what time of irrigation, concentration or volume of NaOCl solution can be of maximum effectiveness in endodontic treatment without producing significant changes in the mechanical properties of dentin. Thus, future human clinical studies are needed in order to resolve these questions.Descriptors: Endodontics; Sodium Hypochlorite; Review.ReferênciasSiqueira JF Jr, Guimarães-Pinto T, Rôças IN. Effects of chemomechanical preparation with 2.5% sodium hypochlorite and intracanal medication with calcium hydroxide on cultivable bacteria in infected root canals. 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Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2004.
Includes bibliographical references (leaves 323-342). Also available in electronic version. Access restricted to campus users.