Bibliografías temáticas / Signaling nanoplatforms

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Literatura académica sobre el tema "Signaling nanoplatforms"

Autor: Grafiati

Publicado: 30 de noviembre de 2024

Última modificación: 31 de julio de 2025

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Artículos de revistas sobre el tema "Signaling nanoplatforms"

Cambi, A., M. Lakadamyali, D. S. Lidke, and M. F. Garcia-Parajo. "Meeting Report - Visualizing signaling nanoplatforms at a higher spatiotemporal resolution." Journal of Cell Science 126, no. 17 (2013): 3817–21. http://dx.doi.org/10.1242/jcs.137901.

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Kim, Hyosuk, Eun Hye Kim, Gijung Kwak, Sung-Gil Chi, Sun Hwa Kim, and Yoosoo Yang. "Exosomes: Cell-Derived Nanoplatforms for the Delivery of Cancer Therapeutics." International Journal of Molecular Sciences 22, no. 1 (2020): 14. http://dx.doi.org/10.3390/ijms22010014.

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Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication, enabling the transfer biological signals from the donor cells to the recipient cells. Recently, exosomes are emerging as promising drug delivery vehicles due to their strong stability in blood circulation, high biocompatibility, low immunogenicity, and natural targeting ability. In particular, exosomes derived from specific types of cells can carry endogenous signaling molecules with therapeutic potential for cancer treat

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Rahbar Saadat, Yalda, and Jaleh Barar. "Exosomes as versatile nanoscaled biocompartments in cancer therapy and/or resistance." BioImpacts 12, no. 2 (2022): 87–88. http://dx.doi.org/10.34172/bi.2022.24253.

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Cancer remains to be a major hurdle to global health. Exosomes as a versatile bio-derived platform, hold a bright prospect in nano-scaled delivery/targeting strategies. Shreds of evidence indicate that exosomes have a critical role in drug resistance in cancer cells through various mechanisms including shuttling of miRNAs, drug efflux transporters, and anti-apoptotic signaling. Exosomes’ cargo, particularly miRNAs, may exert both resistance and in a few cases sensitivity to the anticancer agents in targeted cells. Therefore, the source and components of the exosomes should be carefully conside

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Tang, Yongquan, Yan Chen, Zhe Zhang, Bo Tang, Zongguang Zhou, and Haining Chen. "Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective." Pharmaceutics 13, no. 12 (2021): 2116. http://dx.doi.org/10.3390/pharmaceutics13122116.

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Cancer stem cells (CSCs) are characterized by intrinsic self-renewal and tumorigenic properties, and play important roles in tumor initiation, progression, and resistance to diverse forms of anticancer therapy. Accordingly, targeting signaling pathways that are critical for CSC maintenance and biofunctions, including the Wnt, Notch, Hippo, and Hedgehog signaling cascades, remains a promising therapeutic strategy in multiple cancer types. Furthermore, advances in various cancer omics approaches have largely increased our knowledge of the molecular basis of CSCs, and provided numerous novel targ

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Hattab, Dima, and Athirah Bakhtiar. "Bioengineered siRNA-Based Nanoplatforms Targeting Molecular Signaling Pathways for the Treatment of Triple Negative Breast Cancer: Preclinical and Clinical Advancements." Pharmaceutics 12, no. 10 (2020): 929. http://dx.doi.org/10.3390/pharmaceutics12100929.

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Triple negative breast cancer (TNBC) is one of the most aggressive types of breast cancer. Owing to the absenteeism of hormonal receptors expressed at the cancerous breast cells, hormonal therapies and other medications targeting human epidermal growth factor receptor 2 (HER2) are ineffective in TNBC patients, making traditional chemotherapeutic agents the only current appropriate regimen. Patients’ predisposition to relapse and metastasis, chemotherapeutics’ cytotoxicity and resistance and poor prognosis of TNBC necessitates researchers to investigate different novel-targeted therapeutics. Th

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Tavakol, Ashrafizadeh, Deng, et al. "Autophagy Modulators: Mechanistic Aspects and Drug Delivery Systems." Biomolecules 9, no. 10 (2019): 530. http://dx.doi.org/10.3390/biom9100530.

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Autophagy modulation is considered to be a promising programmed cell death mechanism to prevent and cure a great number of disorders and diseases. The crucial step in designing an effective therapeutic approach is to understand the correct and accurate causes of diseases and to understand whether autophagy plays a cytoprotective or cytotoxic/cytostatic role in the progression and prevention of disease. This knowledge will help scientists find approaches to manipulate tumor and pathologic cells in order to enhance cellular sensitivity to therapeutics and treat them. Although some conventional t

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Serda, Maciej, Katarzyna Malarz, Julia Korzuch, et al. "The Water-Soluble Fullerene Nanomaterials for Pancreatic Cancer Treatment." ECS Meeting Abstracts MA2025-01, no. 11 (2025): 961. https://doi.org/10.1149/ma2025-0111961mtgabs.

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Pancreatic ductal adenocarcinoma (PDAC) is an exceedingly aggressive malignancy characterized by poor prognosis and a five-year survival rate below 5%. Conventional gemcitabine-based chemotherapy remains largely ineffective, and despite intensive efforts to develop novel therapeutics—including nanomedicines, immunotherapies, and gene-based approaches—no truly efficient treatment strategy has yet emerged. In this work, we developed a series of fullerene-based nanoplatforms designed for both the treatment and diagnosis of pancreatic tumors. As a first approach, we focused on modifying standard c

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Bracamonte, Angel Guillermo. "Current Advances in Nanotechnology for the Next Generation of Sequencing (NGS)." Biosensors 13, no. 2 (2023): 260. http://dx.doi.org/10.3390/bios13020260.

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This communication aims at discussing strategies based on developments from nanotechnology focused on the next generation of sequencing (NGS). In this regard, it should be noted that even in the advanced current situation of many techniques and methods accompanied with developments of technology, there are still existing challenges and needs focused on real samples and low concentrations of genomic materials. The approaches discussed/described adopt spectroscopical techniques and new optical setups. PCR bases are introduced to understand the role of non-covalent interactions by discussing abou

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Darie, Costel C., Angiolina Hukovic, Veronica D. Maynard, and Anca-Narcisa Neagu. "Roles of oxygen in the tumorigenesis, progression, and treatment of breast cancer." Medical Gas Research 16, no. 1 (2025): 41–45. https://doi.org/10.4103/mgr.medgasres-d-25-00023.

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Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer death among women worldwide. Poor prognosis in breast cancer patients is often linked to the presence of intratumoral hypoxic areas caused by abnormal vascularization and insufficient oxygen availability, which results in energetic crisis in cancer cells; metabolic and epigenetic reprogramming; the transcription of genes involved in angiogenesis; cancer cell proliferation; increased motility, aggressiveness and metastasis; the accumulation of mutations; genomic instability; the maintenance of stem cell c

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Liang, Xinqiang, Mekhrdod S. Kurboniyon, Yuanhan Zou, et al. "GSH-Triggered/Photothermal-Enhanced H2S Signaling Molecule Release for Gas Therapy." Pharmaceutics 15, no. 10 (2023): 2443. http://dx.doi.org/10.3390/pharmaceutics15102443.

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Traditional treatment methods for tumors are inefficient and have severe side effects. At present, new therapeutic methods such as phototherapy, chemodynamic therapy, and gasodynamic therapy have been innovatively developed. High concentrations of hydrogen sulfide (H2S) gas exhibit cancer-suppressive effects. Herein, a Prussian blue-loaded tetra-sulfide modified dendritic mesoporous organosilica (PB@DMOS) was rationally constructed with glutathione (GSH)-triggered/photothermal-enhanced H2S signaling molecule release properties for gas therapy. The as-synthesized nanoplatform confined PB nanopa

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Tesis sobre el tema "Signaling nanoplatforms"

Maayouf, Hasna. "Développement de plateformes de signalisation dérivées de particules pseudo-virales pour contrôler les fonctions cellulaires." Electronic Thesis or Diss., Mulhouse, 2024. http://www.theses.fr/2024MULH7387.

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Diverses stratégies de fonctionnalisation de surface visent à améliorer la biocompatibilité des matériaux pour les dispositifs implantables, notamment en ingénierie tissulaire. Par exemple, le polydiméthylsiloxane (PDMS), bien qu’utilisé dans de nombreux domaines, présente des propriétés de surface défavorables à l’adhérence cellulaire. La fonctionnalisation par des protéines de la matrice extracellulaire (MEC) ou des peptides synthétiques dérivés de celles-ci permet d’améliorer l'adhérence des cellules. Bien que ces approches offrent certaines solutions, des défis tels que le coût de producti

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