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Tesis sobre el tema "Skin absorption"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 20 de febrero de 2023

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1

Baker, E. J. "Absorption of drugs across the skin." Thesis, University of Nottingham, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378940.

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2

Watkinson, Adam C. "Skin absorption of prostaglandins and related compounds." Thesis, Cardiff University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407992.

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3

Wakefield, James Christopher. "Influence of skin irritation on dermal absorption." Thesis, University of Newcastle upon Tyne, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435596.

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4

Engblom, Johan. "On the phase behaviour of lipids with respect to skin barrier function." Lund, Sweden : Dept. of Food Technology, Lund University, 1996. http://books.google.com/books?id=TdFqAAAAMAAJ.

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5

Ridout, G. "Percutaneous absorption of drugs." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373320.

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6

Neupane, Rabin. "Percutaneous absorption and Skin accumulation of ABH Carbopol gel in Porcine Ear Skin." University of Toledo Health Science Campus / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=mco1556641636092785.

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7

Al-Otaibi, Faisal Obaid. "Pharmacokinetic studies of drug absorption into human skin." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/361.

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Optimum therapeutic outcomes require not only proper drug selection but also effective drug delivery and monitoring. The aim of this thesis was to A) study drug delivery through the skin with a liquid formulated to promote absorption, B) develop and validate methods to analyze the drug in the samples obtained, C) assess appropriate methods to measure the transdermal delivery of drug, and D) apply to pharmacodynamics. The stability of a rectal formulation of diazepam, Diastat®, and a quality control of a topical form, TDS® diazepam, were studied using high performance liquid chromatography (HPL

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8

Lashmar, U. T. "Vehicle effects on percutaneous absorption." Thesis, Open University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370508.

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The availability of a drug from a topical preparation is dependent on many factors, one of the most important being the composition of the vehicle. Glycerol, propylene glycol and polyethylene glycol 200 are widely used as ingredients in topical formulations. The aim of this study was to examine how these glycols affected some of the fundamental factors involved in percutaneous absorption of ethyl- methyl- and glycol salicylate. To do this, certain drug-vehicle, drug-vehicle-skin and vehicle-skin interactions were investigated. Drug-vehicle interactions were evaluated using solubility - and rhe

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9

Hinselwood, David C. "The absorption and metabolism of cinnamic compounds in skin." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501448.

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10

Jung, Connie Tom. "PERCUTANEOUS ABSORPTION OF CATECHOL IN RAT AND HUMAN SKIN." University of Cincinnati / OhioLINK, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=ucin971368708.

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11

Hewitt, Philip Gavin. "In vitro percutaneous absorption of agrochemicals : kinetic and metabolic studies." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309132.

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12

Clark, Nicholas William Edward. "Cutaneous xenobiotic metabolism and its role in percutaneous absorption." Thesis, University of Newcastle Upon Tyne, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317857.

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13

BHATT, VARSHA DILIP. "ABSORPTION AND EVAPORATION OF PESTICIDES FROM HUMAN SKIN IN VITRO." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1179493407.

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14

La, Count Terri D. "Skin Absorption Modeling of Metal Allergens via the Polar Pathway." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397736577.

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15

French, Edward James. "The enhancement of percutaneous absorption by nonionic surfactants." Thesis, University of Bath, 1991. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279431.

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16

Mollee, Thomas. "Mathematical modelling of solute transport through stratum corneum /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18923.pdf.

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17

Davis, Shawn Paul. "Hollow microneedles for molecular transport across skin." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/8055.

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18

Davis, Shawn Paul. "Hollow microneedles for molecular transport across skin." Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-06072004-131118/unrestricted/davis%5Fshawn%5Fp%5F200305%5Fphd.pdf.

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19

Supanpaiboon, Wisa. "Percutaneous absorption and metabolism of naphthalene and phenanthrene." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364851.

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20

Keene, Warren Edward. "Evaluation of microdialysis as a tool for studying percutaneous drug absorption and cutaneous metabolism." Thesis, University of Southampton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268627.

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21

Selzer, Dominik [Verfasser], and Ulrich F. [Akademischer Betreuer] Schäfer. "Mathematical characterization of skin absorption / Dominik Selzer. Betreuer: Ulrich F. Schäfer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2016. http://d-nb.info/1090875673/34.

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22

Burch, Charmita P. "The extent of perturbation of skin models by transdermal penetration enhancers investigated by ³¹P NMR and fluorescence spectroscopy." unrestricted, 2007. http://etd.gsu.edu/theses/available/etd-04252007-133030/.

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Thesis (Ph. D.)--Georgia State University, 2007.<br>Title from thesis title screen. Author's name from thesis title screen. Jerry C. Smith, committee chair; Kathryn Grant, Stuart Allison, committee members. Electronic text (148 p. : ill. (some col.)) : digital PDF file. Description based on contents viewed October 5, 2007. Includes bibliographical references (p. 124-148).

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23

Tonge, Robert Patrick. "The cutaneous disposition of the sensitizing chemicals hydroxycitronellal and dinitrochlorobenzene." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309531.

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24

Traversa, Brigette Danielle. "Enhancement of the percutaneous absorption of the opioid analgesic fentanyl." Monash University, Dept. of Pharmaceutics, 2004. http://arrow.monash.edu.au/hdl/1959.1/9597.

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25

Gonzalez, Helena. "Studies of sunscreens : percutaneous absorption of Benzophenone-3 and photostability /." Göteborg : Department of Dermatology and Venereology, Institute of Clinical Sciences, The Sahlgrenska Academy at Göteborg University, 2006. http://hdl.handle.net/2077/721.

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26

Henry, Sʹebastien. "Microfabricated device for transdermal drug delivery." Thesis, Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/20707.

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27

Dick, Ian Peter. "Factors affecting the dermal absorption of lindane : the use of in vitro and in vivo techniques." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261320.

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28

Gajjar, Rachna M. "Absorption and Evaporation of Volatile Organic Solvents from Human Skin In Vitro." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1282578243.

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29

Doran, Edward M. "Measuring and modeling dermal absorption of pesticide residues /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8454.

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30

SAIYASOMBATI, PENPAN. "MATHEMATICAL MODEL FOR PREDICTING THE PERCUTANEOUS ABSORPTION OF FRANGRANCE RAW MATERIALS." University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1061561348.

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31

Williams, Daffydd Griffin. "Mechanism of action of penetration enhancers." Thesis, Cardiff University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320625.

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32

Demana, Patrick Hulisani. "Tropical corticosteroid bioequivalence testing comparison of chromameter and visual data." Thesis, Rhodes University, 1998. http://hdl.handle.net/10962/d1003233.

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The major criticism of the human skin blanching assay is the subjective nature of grading the response. Recently the American FDA released a Guidance document for topical corticosteroid bioequi valence testing. The guidelines require the use of a chromameter as a reliable method to estimate skin blanching. The purpose of this study was to evaluate the recommendations of this document for appropriateness by comparing visual and chromameter data. The visually-assessed blanching assay methodology routinely practised in our laboratories was modified to comply with the specifications of the Guidanc

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33

Roper, Clive Steven. "In vitro approaches to the prediction of percutaneous absorption and metabolism : a study of ethoxylates." Thesis, University of Newcastle Upon Tyne, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359002.

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34

Ashrafi, Parivash. "Predicting the absorption rate of chemicals through mammalian skin using machine learning algorithms." Thesis, University of Hertfordshire, 2016. http://hdl.handle.net/2299/17310.

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Machine learning (ML) methods have been applied to the analysis of a range of biological systems. This thesis evaluates the application of these methods to the problem domain of skin permeability. ML methods offer great potential in both predictive ability and their ability to provide mechanistic insight to, in this case, the phenomena of skin permeation. Historically, refining mathematical models used to predict percutaneous drug absorption has been thought of as a key factor in this field. Quantitative Structure-Activity Relationships (QSARs) models are used extensively for this purpose. How

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35

Tarnowska, Malgorzata. "Evaluation of skin absorption of inorganic ions with regard to their physicochemical properties." Thesis, Lyon, 2019. https://n2t.net/ark:/47881/m6vm4bkz.

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La peau constitue une interface unique entre l’organisme et son environnement extérieur. Son rôle principal est de protéger les organes internes contre les facteurs externes. Le stratum corneum, est la couche supérieure et très hydrophobe de la peau. Elle était considérée peu perméable pour les molécules hydrophiles chargées tels que les ions inorganiques. Plusieurs études ont démontré le contraire et l’étude récente par Paweloszek et al. a indiqué l’importance du transport actif dans le passage cutanée des ions halogénures. L’absorption cutanée des ions classés selon la série de Hofmeister (F

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36

Dahal, Amit. "Assessment of the Percutaneous Absorption of ABH PLO Gel Across Porcine Ear Skin." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1533321469656146.

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37

Reed, Susan, of Western Sydney Hawkesbury University, and of Science Technology and Environment College. "Development of method to assess skin contact to chemicals." THESIS_CSTE_XXX_Reed_S.xml, 2001. http://handle.uws.edu.au:8081/1959.7/611.

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Chemical exposure of the skin has become a route of entry of some chemicals into the body and has come under major review in recent times. This research aims to develop a method of estimating skin exposure that is both reliable and non-prohibitive in cost. This involved the design and testing of skin patches adaptable for monitoring skin exposure to chemicals using several different types of absorbents which could be easily worn against skin. The final design of the patch used either activated charcoal or tenax as the absorbing medium. The patches were then desorbed with a solvent in order to

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38

Prapopoulou, Maria. "The development of a computation/mathematical model to predict drug absorption across the skin." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/the-development-of-a-computation--mathematical-model-to-predict-drug-absorption-across-the-skin(f82404cb-262e-49e9-af8a-b85b216f2bb8).html.

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The ability to predict accurately the dermal permeation of a chemical is important for the development of new therapeutic formulations in transdermal drug delivery and also for the assessment of the potential risks of environmental chemicals and agents used in cosmetics industry. There have been a large number of studies investigating skin permeability, both experimentally- and theoretically-based. The experimental measurement of skin permeability is a time-consuming and difficult process and, when put in the context of the great numbers of chemicals that may come into contact with the skin, i

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39

Lockley, David Jason. "Percutaneous absorption and metabolism of glycol ethers : predictions by an in vitro approach." Thesis, University of Newcastle Upon Tyne, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311131.

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40

Golmohammadi, Arash. "Percutaneous penetration of parabens through the human epidermal membrane /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18696.pdf.

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41

Smith, Eric W. "Aspects of the transdermal permeation and analysis of betamethasone 17-valerate." Thesis, Rhodes University, 1988. http://hdl.handle.net/10962/d1004741.

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The current world-wide interest in transdermal drug delivery makes the prospect of valid in vitro diffusion cell methodology highly attractive. A new laboratory diffusion cell has been designed and constructed based on theoretical principles and practical permeation reports surveyed in recent literature, and has been applied to the monitoring of betamethasone 17-valerate permeation. The cell performance has been validated with respect to hydrodynamic mixing efficiency and temperature of the receptor phase. The steady-state permeation of this corticosteroid has been monitored through various sy

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42

Pefile, Sibongile C. "A study of the transdermal drug diffusion properties of rooperol tetra-acetate." Thesis, Rhodes University, 1998. http://hdl.handle.net/10962/d1007649.

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The rapidly growing interest in the potential use of topical drug delivery formulations has resulted in increased use of the skin as a vital port for drug delivery. Extensive research has been conducted in designing vehicles capable of delivering a desired amount of drug to a specific site, to produce the desired pharmacological response. Rooperol tetra-acetate is a lipophilic, cytotoxic drug with the potential for use in the treatment of solar keratosis. For effective pharmacological action, delivery of the drug to the epidermal/dermal junction of the skin is required. A study of the topical

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43

SANTHANAM, ARJUN. "MATHEMATICAL MODEL TO PREDICT THE SKIN DISPOSITION OF DEET AND OTHER VOLATILE COMPOUNDS." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1092343602.

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44

Karr, Jennifer I. "A novel encapsulation favorably modifies the skin disposition of topically-applied N,N-diethyl-3-methylbenzamide (DEET)." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1353154812.

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45

Reed, Susan. "Development of method to assess skin contact to chemicals /." View thesis View thesis, 2001. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030520.115134/index.html.

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Thesis (Ph.D.) -- University of Western Sydney, Hawkesbury, 2001.<br>A thesis presented in fulfilment of the requirement for the degree of Doctor of Philosophy, College of Science, Technology and Environment, University of Western Sydney, Richmond, April 2001. Bibliography : leaves 138-148.

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46

Ray, Chaudhuri Siladitya. "Mathematical Modeling of Percutaneous Absorption of Volatile Solvents Following Transient Liquid-Phase Exposures." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1179468433.

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47

LIMA, CASSIO A. "Caracterização bioquímica de lesões neoplásicas via espectroscopia de absorção no infravermelho por transformada de Fourier." reponame:Repositório Institucional do IPEN, 2015. http://repositorio.ipen.br:8080/xmlui/handle/123456789/23986.

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Submitted by Claudinei Pracidelli (cpracide@ipen.br) on 2015-10-22T16:48:07Z No. of bitstreams: 0<br>Made available in DSpace on 2015-10-22T16:48:07Z (GMT). No. of bitstreams: 0<br>Dissertação (Mestrado em Tecnologia Nuclear)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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48

CARDOSO, TALITA R. "Aplicabilidade de curativos a base de hidrogel com nanopartículas de prata em lesão por pressão." reponame:Repositório Institucional do IPEN, 2017. http://repositorio.ipen.br:8080/xmlui/handle/123456789/27972.

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Submitted by Marco Antonio Oliveira da Silva (maosilva@ipen.br) on 2017-11-09T11:05:48Z No. of bitstreams: 0<br>Made available in DSpace on 2017-11-09T11:05:48Z (GMT). No. of bitstreams: 0<br>Cuidar de feridas é um processo dinâmico e complexo que requer atenção especial principalmente quando se refere a uma lesão crônica. A lesão por pressão (LPP) é uma ferida crônica localizada na pele ou no tecido subjacente, geralmente sobre uma proeminência óssea, resultante de pressão isolada ou pressão combinada com fricção ou cisalhamento. O objetivo foi avaliar a aplicabilidade das membranas de hidro

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49

Intarakumhaeng, Rattikorn. "Factors Influencing Percutaneous Absorption:Effects of Solvents, Solute Physicochemical Properties, and Penetration Enhancer." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1491316295006087.

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50

Alsaab, Hashem O. "Evaluation of the Percutaneous Absorption of Chlorpromazine Hydrochloride from PLO Gels Across Porcine Ear and Human Abdominal Skin." University of Toledo Health Science Campus / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=mco1435670713.

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