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Artículos de revistas sobre el tema "Slow dynamic interactions"

Autor: Grafiati
Publicado: 11 de enero de 2025
Última modificación: 31 de julio de 2025

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1

Kitazawa, Soichiro, Maho Yagi-Utsumi, Koichi Kato, and Ryo Kitahara. "Interactions Controlling the Slow Dynamic Conformational Motions of Ubiquitin." Molecules 22, no. 9 (2017): 1414. http://dx.doi.org/10.3390/molecules22091414.

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2

Ashwin, S. S., Tadasu Nozaki, Kazuhiro Maeshima, and Masaki Sasai. "Organization of fast and slow chromatin revealed by single-nucleosome dynamics." Proceedings of the National Academy of Sciences 116, no. 40 (2019): 19939–44. http://dx.doi.org/10.1073/pnas.1907342116.

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Understanding chromatin organization and dynamics is important, since they crucially affect DNA functions. In this study, we investigate chromatin dynamics by statistically analyzing single-nucleosome movement in living human cells. Bimodal nature of the mean square displacement distribution of nucleosomes allows for a natural categorization of the nucleosomes as fast and slow. Analyses of the nucleosome–nucleosome correlation functions within these categories along with the density of vibrational modes show that the nucleosomes form dynamically correlated fluid regions (i.e., dynamic domains
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3

Williams, R. E., and S. M. Horvath. "Recovery from dynamic exercise." American Journal of Physiology-Heart and Circulatory Physiology 268, no. 6 (1995): H2311—H2320. http://dx.doi.org/10.1152/ajpheart.1995.268.6.h2311.

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Minimal information is available on the basic interactions within the metabolic and cardiovascular systems during recovery from exercise. Nine men participated in three experiments: one control and two cost-equivalent (52 liters O2) exercise tests of 30 (EX30) and 45 (EX45) min. Exercise intensities were adjusted accordingly. During recovery, all parameters reestablished baseline levels within 10 min, except for heart rate (30 min). Correlations for each parameter for EX30 and EX45 were obtained by evaluating each subject's exercise cost and recovery "payback." A split, two-factor analysis of
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4

Jitapunkul, Kulpavee, Pisanu Toochinda та Luckhana Lawtrakul. "Molecular Dynamic Simulation Analysis on the Inclusion Complexation of Plumbagin with β-Cyclodextrin Derivatives in Aqueous Solution". Molecules 26, № 22 (2021): 6784. http://dx.doi.org/10.3390/molecules26226784.

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Stable encapsulation of medically active compounds can lead to longer storage life and facilitate the slow-release mechanism. In this work, the dynamic and molecular interactions between plumbagin molecule with β-cyclodextrin (BCD) and its two derivatives, which are dimethyl-β-cyclodextrin (MBCD), and 2-O-monohydroxypropyl-β-cyclodextrin (HPBCD) were investigated. Molecular dynamics simulations (MD) with GLYCAM-06 and AMBER force fields were used to simulate the inclusion complex systems under storage temperature (4 °C) in an aqueous solution. The simulation results suggested that HPBCD is the
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5

Garbett, Damien, and Anthony Bretscher. "PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli." Journal of Cell Biology 198, no. 2 (2012): 195–203. http://dx.doi.org/10.1083/jcb.201204008.

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Scaffolding proteins containing PDZ (postsynaptic density 95/discs large/zonula occludens-1) domains are believed to provide relatively stable linkages between components of macromolecular complexes and in some cases to bridge to the actin cytoskeleton. The microvillar scaffolding protein EBP50 (ERM-binding phosphoprotein of 50 kD), consisting of two PDZ domains and an ezrin-binding site, retains specific proteins in microvilli and is necessary for microvillar biogenesis. Our analysis of the dynamics of microvillar proteins in vivo indicated that ezrin and microvillar membrane proteins had dyn
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6

Chen, Xue-Qing, and Lei Tong. "Multiscale flow characteristics of droplet spreading with microgravity conditions." Canadian Journal of Physics 97, no. 8 (2019): 869–74. http://dx.doi.org/10.1139/cjp-2018-0474.

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In this paper, mesoscopic lattice–Boltzmann method (LBM) and microscopic molecular dynamics simulation method were used to simulate droplet dynamic wetting under microgravity. In terms of LBM, the wetting process of a droplet on a solid wall surface was simulated by introducing the fluid–fluid and solid–fluid interactions. In terms of molecular dynamics simulation, the spreading process of water on gold surface was simulated. Calculation results showed that two kinds of calculation methods were based on the microscopic molecular theory or mesoscopic kinetics theory, and such models could effec
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7

Grossman-Haham, Iris, Gabriel Rosenblum, Trishool Namani, and Hagen Hofmann. "Slow domain reconfiguration causes power-law kinetics in a two-state enzyme." Proceedings of the National Academy of Sciences 115, no. 3 (2018): 513–18. http://dx.doi.org/10.1073/pnas.1714401115.

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Protein dynamics are typically captured well by rate equations that predict exponential decays for two-state reactions. Here, we describe a remarkable exception. The electron-transfer enzyme quiescin sulfhydryl oxidase (QSOX), a natural fusion of two functionally distinct domains, switches between open- and closed-domain arrangements with apparent power-law kinetics. Using single-molecule FRET experiments on time scales from nanoseconds to milliseconds, we show that the unusual open-close kinetics results from slow sampling of an ensemble of disordered domain orientations. While substrate acce
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8

Yin, Chunyue, and Lilianna Solnica-Krezel. "Convergence and extension movements affect dynamic notochord-somite interactions essential for zebrafish slow muscle morphogenesis." Developmental Dynamics 236, no. 10 (2007): 2742–56. http://dx.doi.org/10.1002/dvdy.21295.

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9

PEIRSON, WILLIAM L., and ANDREW W. GARCIA. "On the wind-induced growth of slow water waves of finite steepness." Journal of Fluid Mechanics 608 (July 11, 2008): 243–74. http://dx.doi.org/10.1017/s002211200800205x.

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Determining characteristic growth rates for water waves travelling more slowly than the wind has continued to be a key unresolved problem of air–sea interaction for over half a century. Analysis of previously reported and recently acquired laboratory wave data shows a systematic decline in normalized wave growth with increasing mean wave steepness that has not previously been identified. The normalized growth dynamic range is comparable with previously observed scatter amongst other laboratory data gathered in the slow wave range. Strong normalized growth rates are observed at low wave steepne
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10

Yen, Shih-Hsiang, Pei-Chong Tang, Yuan-Chiu Lin, and Chyi-Yeu Lin. "A Sensorless and Low-Gain Brushless DC Motor Controller Using a Simplified Dynamic Force Compensator for Robot Arm Application." Sensors 19, no. 14 (2019): 3171. http://dx.doi.org/10.3390/s19143171.

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Robot arms used for service applications require safe human–machine interactions; therefore, the control gain of such robot arms must be minimized to limit the force output during operation, which slows the response of the control system. To improve cost efficiency, low-resolution sensors can be used to reduce cost because the robot arms do not require high precision of position sensing. However, low-resolution sensors slow the response of closed-loop control systems, leading to low accuracy. Focusing on safety and cost reduction, this study proposed a low-gain, sensorless Brushless DC motor c
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11

Abdelghafor, Z., G. Taimuri, P. Kujala, Y. Wang, and S. Hirdaris. "Numerical studies on tugboat performance during pushing operations." IOP Conference Series: Materials Science and Engineering 1288, no. 1 (2023): 012003. http://dx.doi.org/10.1088/1757-899x/1288/1/012003.

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Abstract This paper introduces a RANS CFD methodology for the evaluation of tugboat dynamics during pushing operations. Two- and three- dimensional methods that respectively utilize “Dynamic Fluid Body Interactions - (DFBI)” and “Tug Force Equilibrium kinematics-(TFE)” are assessed and compared with the aim to better understand the influence of fluid modelling on ship dynamics. For the DFBI method, an unsteady RANS solver comprising of a dynamic fluid body interaction module and a contact mechanics coupling algorithm are used to predict the forces between a tugboat and an assisted ship. For th
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12

Aebischer, Kathrin, Lea Marie Becker, Paul Schanda, and Matthias Ernst. "Evaluating the motional timescales contributing to averaged anisotropic interactions in MAS solid-state NMR." Magnetic Resonance 5, no. 1 (2024): 69–86. http://dx.doi.org/10.5194/mr-5-69-2024.

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Abstract. Dynamic processes in molecules can occur on a wide range of timescales, and it is important to understand which timescales of motion contribute to different parameters used in dynamics measurements. For spin relaxation, this can easily be understood from the sampling frequencies of the spectral-density function by different relaxation-rate constants. In addition to data from relaxation measurements, determining dynamically averaged anisotropic interactions in magic-angle spinning (MAS) solid-state NMR allows for better quantification of the amplitude of molecular motion. For partiall
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13

Dell'Orco, Daniele, and Karl-Wilhelm Koch. "A dynamic scaffolding mechanism for rhodopsin and transducin interaction in vertebrate vision." Biochemical Journal 440, no. 2 (2011): 263–71. http://dx.doi.org/10.1042/bj20110871.

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The early steps in vertebrate vision require fast interactions between Rh (rhodopsin) and Gt (transducin), which are classically described by a collisional coupling mechanism driven by the free diffusion of monomeric proteins on the disc membranes of rod and cone cells. Recent findings, however, point to a very low mobility for Rh and support a substantially different supramolecular organization. Moreover, Rh–Gt interactions seem to possibly occur even prior to light stimuli, which is also difficult to reconcile with the classical scenario. We investigated the kinetics of interaction between n
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14

Shahravi, Morteza, and Milad Azimi. "A Hybrid Scheme of Synthesized Sliding Mode/Strain Rate Feedback Control Design for Flexible Spacecraft Attitude Maneuver Using Time Scale Decomposition." International Journal of Structural Stability and Dynamics 16, no. 02 (2016): 1450101. http://dx.doi.org/10.1142/s0219455414501016.

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Presented herein is a new control approach for large angle attitude maneuver of flexible spacecraft. The singular perturbation theory (SPT) provides a useful tool for two time rate scale separation (mapping) of rigid and flexible body dynamics. The resulting slow and fast subsystems, enabling the use of two control approach for attitude (Modified Sliding Mode) and vibration Strain Rate Feedback (SRF) control of flexible spacecraft, respectively. An attractive feature of the present control approach is that the global stability of the entire system has been guaranteed while the controllers acco
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15

Salvi, Nicola, Simone Ulzega, Fabien Ferrage, and Geoffrey Bodenhausen. "Time scales of slow motions in ubiquitin explored by heteronuclear double resonance." Journal of the American Chemical Society 134, no. 5 (2012): 2481–84. https://doi.org/10.1021/ja210238g.

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International audience ; Understanding how proteins function at the atomic level relies in part on a detailed characterization of their dynamics. Ubiquitin, a small single-domain protein, displays rich dynamic properties over a wide range of time scales. In particular, several regions of ubiquitin show the signature of chemical exchange, including the hydrophobic patch and the β4-α2 loop, which are both involved in many interactions. Here, we use multiple-quantum relaxation techniques to identify the extent of chemical exchange in ubiquitin. We employ our recently developed heteronuclear doubl
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16

Manna, Balaram, Pramodh Bharati, Subrata Paul, et al. "Results and Discussion of Dengue Model with Temperature Effects in Interval Environment." SciNexuses 1 (September 3, 2024): 75–81. http://dx.doi.org/10.61356/j.scin.2024.1372.

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We have investigated a dengue model with temperature effects under interval uncertainty in this work. This study observed the Aedes aegypti temperature-dependent entomological parameters that affect dengue illness transmission dynamics in Taiwan's subtropical zone. A vector-host transmission model was used to examine how temperature fluctuations influence the development of pre-adult mosquitoes, their egg-laying rates, adult mortality, and the incubation rate of viruses within them. This study showed that although estimations of entomological parameters were positively correlated with slow tem
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17

Neverova, G. P., and O. L. Zhdanova. "Comparative Dynamics Analysis of Simple Mathematical Models of the Plankton Communities Considering Various Types of Response Function." Mathematical Biology and Bioinformatics 17, no. 2 (2022): 465–80. http://dx.doi.org/10.17537/2022.17.465.

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The paper proposes a two-component discrete-time model of the plankton community, taking into account features of the development and interaction of phytoplankton and zooplankton. To describe the interaction between these species and to compare the system dynamics, we use the following set of response functions: type II and III Holling function and the Arditi–Ginzburg response function, each of which describes trophic interactions between phytoplankton and zooplankton. An analytical and numerical study of the model proposed is made. The analysis shows that the variation of trophic functions do
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18

Leleu, Timothée, and Kazuyuki Aihara. "Spontaneous Slow Oscillations and Sequential Patterns Due to Short-Term Plasticity in a Model of the Cortex." Neural Computation 25, no. 12 (2013): 3131–82. http://dx.doi.org/10.1162/neco_a_00513.

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We study a realistic model of a cortical column taking into account short-term plasticity between pyramidal cells and interneurons. The simulation of leaky integrate-and-fire neurons shows that low-frequency oscillations emerge spontaneously as a result of intrinsic network properties. These oscillations are composed of prolonged phases of high and low activity reminiscent of cortical up and down states, respectively. We simplify the description of the network activity by using a mean field approximation and reduce the system to two slow variables exhibiting some relaxation oscillations. We id
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19

Stefan, Ana-Teodora, Cristina Craioveanu, and Alexandru Nicolae Stermin. "Forage, Preen or Fight? A Study of Interspecific Water Bird Interactions at Crișul Repede River." Studia Universitatis Babes-Bolyai Biologia 70, no. 1 (2025): 287–302. https://doi.org/10.24193/subbbiol.2025.1.13.

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Analyzing the behavior of birds offers insight into the conservation of biodiversity, a heavily discussed subject in the fields of ecology as well as ornithology. As it has been previously proven (Rushton et al., 1994), slow-flowing areas of rivers represent important habitats for birds all throughout the year and the conservation of this type of habitats has been known to have a positive effect on the population of many water bird species (Rolls et al., 2012). Therefore, this study explores the dynamic of interspecific interactions between water birds in open water areas from the Afon Peța po
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20

Yeon, Jun-Hee, Cheon-Gyu Park, Bertil Hille та Byung-Chang Suh. "Translocatable voltage-gated Ca2+ channel β subunits in α1–β complexes reveal competitive replacement yet no spontaneous dissociation". Proceedings of the National Academy of Sciences 115, № 42 (2018): E9934—E9943. http://dx.doi.org/10.1073/pnas.1809762115.

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β subunits of high voltage-gated Ca2+ (CaV) channels promote cell-surface expression of pore-forming α1 subunits and regulate channel gating through binding to the α-interaction domain (AID) in the first intracellular loop. We addressed the stability of CaV α1B–β interactions by rapamycin-translocatable CaV β subunits that allow drug-induced sequestration and uncoupling of the β subunit from CaV2.2 channel complexes in intact cells. Without CaV α1B/α2δ1, all modified β subunits, except membrane-tethered β2a and β2e, are in the cytosol and rapidly translocate upon rapamycin addition to anchors
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21

Zeng, Zhen, Elisa L. Hill-Yardin, David Williams, Terence O'Brien, Andris Serelis, and Christopher R. French. "Effect of phenytoin on sodium conductances in rat hippocampal CA1 pyramidal neurons." Journal of Neurophysiology 116, no. 4 (2016): 1924–36. http://dx.doi.org/10.1152/jn.01060.2015.

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The antiepileptic drug phenytoin (PHT) is thought to reduce the excitability of neural tissue by stabilizing sodium channels (NaV) in inactivated states. It has been suggested the fast-inactivated state (IF) is the main target, although slow inactivation (IS) has also been implicated. Other studies on local anesthetics with similar effects on sodium channels have implicated the NaV voltage sensor interactions. In this study, we reexamined the effect of PHT in both equilibrium and dynamic transitions between fast and slower forms of inactivation in rat hippocampal CA1 pyramidal neurons. The eff
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22

Zmigrod, Leor, and Amit Goldenberg. "Cognition and Emotion in Extreme Political Action: Individual Differences and Dynamic Interactions." Current Directions in Psychological Science 30, no. 3 (2021): 218–27. http://dx.doi.org/10.1177/0963721421993820.

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Who is most likely to join and engage in extreme political action? Although traditional theories have focused on situational factors or group identity, an emerging science illustrates that tendencies for extreme political action may also be rooted in individuals’ idiosyncratic cognitive and affective dispositions. This article synthesizes cutting-edge evidence demonstrating that individuals’ cognitive and affective architecture shapes their willingness to support ideological violence. In the cognitive domain, traits such as cognitive rigidity, slow perceptual strategies, and poor executive fun
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23

Li, Xin, Wei Huang, Elizabeth A. Morris, et al. "Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI." Proceedings of the National Academy of Sciences 105, no. 46 (2008): 17937–42. http://dx.doi.org/10.1073/pnas.0804224105.

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The passage of a vascular-injected paramagnetic contrast reagent (CR) bolus through a region-of-interest affects tissue 1H2O relaxation and thus MR image intensity. For longitudinal relaxation [R1 ≡ (T1)−1], the CR must have transient molecular interactions with water. Because the CR and water molecules are never uniformly distributed in the histological-scale tissue compartments, the kinetics of equilibrium water compartmental interchange are competitive. In particular, the condition of the equilibrium trans cytolemmal water exchange NMR system sorties through different domains as the interst
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24

Osunkoya, Kofoworola Modupe, and Jenni Partanen. "Enhancing urban vitality: integrating traditional metrics with big data and socio-economic insights." Journal of Spatial Information Science, no. 29 (December 26, 2024): 43–68. https://doi.org/10.5311/josis.2024.29.357.

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A city is an intricate system where interactions between transport, land use, the environment, and the population occur at various scales. This complexity makes it challenging to predict and govern these interactions. However, big data on human activity patterns allows researchers to discover dynamic, temporary patterns in the activity landscape and understand the choreographies of people's behavior to enhance urban areas' vitality through planning. In this article, we hypothesized that a higher diversity of urban spatio-functional and socio-economic features indicates higher urban vitality in
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25

Xie, Mouzhe, Lei Yu, Lei Bruschweiler-Li, Xinyao Xiang, Alexandar L. Hansen, and Rafael Brüschweiler. "Functional protein dynamics on uncharted time scales detected by nanoparticle-assisted NMR spin relaxation." Science Advances 5, no. 8 (2019): eaax5560. http://dx.doi.org/10.1126/sciadv.aax5560.

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Protein function depends critically on intrinsic internal dynamics, which is manifested in distinct ways, such as loop motions that regulate protein recognition and catalysis. Under physiological conditions, dynamic processes occur on a wide range of time scales from subpicoseconds to seconds. Commonly used NMR spin relaxation in solution provides valuable information on very fast and slow motions but is insensitive to the intermediate nanosecond to microsecond range that exceeds the protein tumbling correlation time. Presently, very little is known about the nature and functional role of thes
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26

Kruteva, Margarita. "Dynamics studied by Quasielastic Neutron Scattering (QENS)." Adsorption 27, no. 5 (2021): 875–89. http://dx.doi.org/10.1007/s10450-020-00295-4.

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AbstractQuasielastic neutron scattering (QENS) allows measurement of the molecular displacements in time and space, from pico- to tens of nanoseconds and from Ångstroms to nanometers, respectively. The method probes dynamics from fast vibrational modes down to slow diffusive motion. Every scattering experiment leads to a dynamic structure factor $$S\left( {\vec Q,\omega } \right)$$ S Q → , ω or its spatial and temporal Fourier transform (van Hove correlation function $$G\left( {\vec r,t} \right)$$ G r → , t ). This shows exactly where the atoms are and how they move. In this manuscript the bas
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27

Grebowsky, Joseph M., and Arthur C. Aikin. "Planetary ionospheres – sources and dynamic drivers." Proceedings of the International Astronomical Union 4, S257 (2008): 499–510. http://dx.doi.org/10.1017/s1743921309029780.

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AbstractExternal energy inputs into all planetary upper atmospheres (including more than a half dozen moons with atmospheres) are comprised of combinations of solar EUV, soft x-rays, solar energetic particles, solar wind charged particles, magnetospherically accelerated particles, solar wind electric field, interplanetary dust particles as well as propagating lower atmosphere disturbances. Each input has analogous physical interactions with all planetary ionospheres and upper atmospheres, but the integrated consequences of the multiple energy inputs vary from planet to planet. The Earth forms
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28

Dupraz, Christian, Kevin Wolz, Isabelle Lecomte, et al. "Hi-sAFe: A 3D Agroforestry Model for Integrating Dynamic Tree–Crop Interactions." Sustainability 11, no. 8 (2019): 2293. http://dx.doi.org/10.3390/su11082293.

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Agroforestry, the intentional integration of trees with crops and/or livestock, can lead to multiple economic and ecological benefits compared to trees and crops/livestock grown separately. Field experimentation has been the primary approach to understanding the tree–crop interactions inherent in agroforestry. However, the number of field experiments has been limited by slow tree maturation and difficulty in obtaining consistent funding. Models have the potential to overcome these hurdles and rapidly advance understanding of agroforestry systems. Hi-sAFe is a mechanistic, biophysical model des
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29

Liu, Shuang, Jun-Fang Wu, and Chao Li. "Reconfigurable optical diode based on asymmetrically coupled slow-light waveguide." Journal of Applied Physics 133, no. 4 (2023): 043105. http://dx.doi.org/10.1063/5.0133804.

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Controlling the flow of light is fundamental for on-chip optical signal processing. In this paper, we investigate how to realize high contrast, high unidirectional transmission rate, and reconfigurable nonreciprocal light transmission, based on a nonlinear nanocavity asymmetrically side-coupled with a specially designed slow-light waveguide. We analytically and numerically demonstrate that the unusual multiple threshold pump power points for trigging the photon transitions between bistable states, as well as the sensitivity of the dynamic interactions to the relative delay time between the sig
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30

Pimentel, Sam, and Gwenn E. Flowers. "A numerical study of hydrologically driven glacier dynamics and subglacial flooding." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 467, no. 2126 (2010): 537–58. http://dx.doi.org/10.1098/rspa.2010.0211.

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A hydrologically coupled flowband model of ‘higher order’ ice dynamics is used to explore perturbations in response to supraglacial water drainage and subglacial flooding. The subglacial drainage system includes interacting ‘fast’ and ‘slow’ drainage elements. The fast drainage system is assumed to be composed of ice-walled conduits and the slow system of a macroporous water sheet. Under high subglacial water pressures, flexure of the overlying ice is modelled using elastic beam theory. A regularized Coulomb friction law describes basal boundary conditions that enable hydrologically driven acc
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31

Joseph, Prem, Leo Spyracopoulos, and Krishna Rajarathnam. "Dynamics-Derived Insights into Complex Formation between the CXCL8 Monomer and CXCR1 N-Terminal Domain: An NMR Study." Molecules 23, no. 11 (2018): 2825. http://dx.doi.org/10.3390/molecules23112825.

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Interleukin-8 (CXCL8), a potent neutrophil-activating chemokine, exerts its function by activating the CXCR1 receptor that belongs to class A G protein-coupled receptors (GPCRs). Receptor activation involves interactions between the CXCL8 N-terminal loop and CXCR1 N-terminal domain (N-domain) residues (Site-I) and between the CXCL8 N-terminal and CXCR1 extracellular/transmembrane residues (Site-II). CXCL8 exists in equilibrium between monomers and dimers, and it is known that the monomer binds CXCR1 with much higher affinity and that Site-I interactions are largely responsible for the differen
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32

Luo, Feng, Yu-Mei Song, Hai-Xiao Huang, et al. "Two New One-Dimensional Homospin Dy(III) Compounds Showing Slow Magnetic Relaxation." Australian Journal of Chemistry 65, no. 10 (2012): 1436. http://dx.doi.org/10.1071/ch12233.

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In this work, we present two new one-dimensional Dy(iii) compounds, namely [Dy3(L1)9]n (1, HL1 = benzoic acid) and {[Dy4(L2)14][Fe(phen)3]}n (2, HL2 = 3-nitrobenzoic acid, phen = 1,10-phenanthroline). In 1, three distinct coordination polyhedra for Dy(iii) sites including a six-coordinated DyO6 octahedron, a seven-coordinated DyO7 pentagonal bipyramid, and eight-coordinated DyO8 dodecahedron, are observed. These Dy(iii) ions are in turn bridged by L1––carboxylate to give rise to the 1D helical chain structure. Within 2, there are two crystallography-independent Dy(iii) ions that take the mono-
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33

Daumas, F., N. Destainville, C. Millot, A. Lopez, D. Dean, and L. Salomé. "Interprotein interactions are responsible for the confined diffusion of a G-protein-coupled receptor at the cell surface." Biochemical Society Transactions 31, no. 5 (2003): 1001–5. http://dx.doi.org/10.1042/bst0311001.

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The monitoring of the movements of membrane proteins (or lipids) by single-particle tracking enables one to obtain reliable insights into the complex dynamic organization of the plasma membrane constituents. Using this technique, we investigated the diffusional behaviour of a G-protein-coupled receptor. The trajectories of the receptors revealed a diffusion mode combining a short-term rapid confined diffusion with a long-term slow diffusion. A detailed statistical analysis shows that the receptors have a diffusion confined to a domain which itself diffuses, the confinement being due to long-ra
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34

Gupta, Shamik, and Stefano Ruffo. "The world of long-range interactions: A bird’s eye view." International Journal of Modern Physics A 32, no. 09 (2017): 1741018. http://dx.doi.org/10.1142/s0217751x17410184.

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In recent years, studies of long-range interacting (LRI) systems have taken center stage in the arena of statistical mechanics and dynamical system studies, due to new theoretical developments involving tools from as diverse a field as kinetic theory, non-equilibrium statistical mechanics, and large deviation theory, but also due to new and exciting experimental realizations of LRI systems. In the first, introductory, Section 1, we discuss the general features of long-range interactions, emphasizing in particular the main physical phenomenon of non-additivity, which leads to a plethora of dist
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35

Hua, Siyu, Xugang Wang, and Zhongyuan Wang. "Rigid–Elastic Coupling Dynamics of Morphing Wing Aircraft." Aerospace 12, no. 4 (2025): 327. https://doi.org/10.3390/aerospace12040327.

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This paper presents a rigid–elastic coupling dynamic model for a morphing aircraft with variable-sweep wings, developed using Kane’s method. The model accurately captures the interactions between flight dynamics and structural dynamics during morphing. To fully account for the coupling effects, we derive a morphing aircraft model consisting of a rigid fuselage and two elastic wings. Each wing is modeled as a straight beam undergoing small elastic deformations while experiencing large overall motions following the fuselage in space, along with variable-sweep rotations relative to the fuselage.
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36

Flores-Aldama, Lisandra, Daniel Bustos, Deny Cabezas-Bratesco, Wendy Gonzalez, and Sebastian E. Brauchi. "Intracellular Helix-Loop-Helix Domain Modulates Inactivation Kinetics of Mammalian TRPV5 and TRPV6 Channels." International Journal of Molecular Sciences 24, no. 5 (2023): 4470. http://dx.doi.org/10.3390/ijms24054470.

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TRPV5 and TRPV6 are calcium-selective ion channels expressed at the apical membrane of epithelial cells. Important for systemic calcium (Ca2+) homeostasis, these channels are considered gatekeepers of this cation transcellular transport. Intracellular Ca2+ exerts a negative control over the activity of these channels by promoting inactivation. TRPV5 and TRPV6 inactivation has been divided into fast and slow phases based on their kinetics. While slow inactivation is common to both channels, fast inactivation is characteristic of TRPV6. It has been proposed that the fast phase depends on Ca2+ bi
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37

Sengel, Jason T., and Mark I. Wallace. "Imaging the dynamics of individual electropores." Proceedings of the National Academy of Sciences 113, no. 19 (2016): 5281–86. http://dx.doi.org/10.1073/pnas.1517437113.

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Electroporation is a widely used technique to permeabilize cell membranes. Despite its prevalence, our understanding of the mechanism of voltage-mediated pore formation is incomplete; methods capable of visualizing the time-dependent behavior of individual electropores would help improve our understanding of this process. Here, using optical single-channel recording, we track multiple isolated electropores in real time in planar droplet interface bilayers. We observe individual, mobile defects that fluctuate in size, exhibiting a range of dynamic behaviors. We observe fast (25 s−1) and slow (2
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38

Julien, Claude, Bruno Chapuis, Yong Cheng, and Christian Barrès. "Dynamic interactions between arterial pressure and sympathetic nerve activity: role of arterial baroreceptors." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 285, no. 4 (2003): R834—R841. http://dx.doi.org/10.1152/ajpregu.00102.2003.

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The role of arterial baroreceptors in controlling arterial pressure (AP) variability through changes in sympathetic nerve activity was examined in conscious rats. AP and renal sympathetic nerve activity (RSNA) were measured continuously during 1-h periods in freely behaving rats that had been subjected to sinoaortic baroreceptor denervation (SAD) or a sham operation 2 wk before study ( n = 10 in each group). Fast Fourier transform analysis revealed that chronic SAD did not alter high-frequency (0.75-5 Hz) respiratory-related oscillations of mean AP (MAP) and RSNA, decreased by ∼50% spectral po
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39

Siregar, Yusra Dewi, Ilham Aji Maulana, Deswita Saskia Humairah Manik, and Siti Syarah Hutasiot. "Pengaruh Masuknya Islam Terhadap Kebudayaan di Tanah Karo." Islam & Contemporary Issues 4, no. 1 (2024): 28–34. http://dx.doi.org/10.57251/ici.v4i1.1415.

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This study aims to examine the influence of the arrival of Islam on the culture in Tanah Karo, which was previously dominated by animism and dynamism beliefs. Through the literature review method, this research analyzes changes in the belief system, customs, marriage patterns, education, and social dynamics after Islam was introduced in the region. The findings show that interactions between Islamic traders and scholars with the indigenous Karo community triggered a slow but significant process of acculturation. Traditional Karo culture underwent a transformation, adopting Islamic values in va
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40

Horn, John P. "The integrative role of synaptic cotransmission in the bullfrog vasomotor C system: evidence for a synaptic gain hypothesis." Canadian Journal of Physiology and Pharmacology 70, S1 (1992): S19—S26. http://dx.doi.org/10.1139/y92-239.

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Understanding the integrative significance of synaptic cotransmission is a central problem in autonomic physiology. What are the functional roles of slow synaptic potentials in autonomic ganglia? This paper reviews the problem and its historical roots by focusing on work in the amphibian paravertebral sympathetic system. The phenotypic properties that distinguish the sympathetic B and C cell systems are summarized. Then, a synaptic gain hypothesis is proposed for the integrative function of muscarinic and peptidergic synapses in the vasomotor C system. The model states that the peripheral outp
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41

Gemmell, Brad J., Sean P. Colin, John H. Costello, and Kelly R. Sutherland. "A ctenophore (comb jelly) employs vortex rebound dynamics and outperforms other gelatinous swimmers." Royal Society Open Science 6, no. 3 (2019): 181615. http://dx.doi.org/10.1098/rsos.181615.

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Gelatinous zooplankton exhibit a wide range of propulsive swimming modes. One of the most energetically efficient is the rowing behaviour exhibited by many species of schyphomedusae, which employ vortex interactions to achieve this result. Ctenophores (comb jellies) typically use a slow swimming, cilia-based mode of propulsion. However, species within the genus Ocyropsis have developed an additional propulsive strategy of rowing the lobes, which are normally used for feeding, in order to rapidly escape from predators. In this study, we used high-speed digital particle image velocimetry to exam
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42

Nicolaidou, Evangelia, Thomas L. Hill, and Simon A. Neild. "Detecting internal resonances during model reduction." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 477, no. 2250 (2021): 20210215. http://dx.doi.org/10.1098/rspa.2021.0215.

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Model order reduction of geometrically nonlinear dynamic structures is often achieved via a static condensation procedure, whereby high-frequency modes are assumed to be quasi-statically coupled to a small set of lower frequency modes, which form the reduction basis. This approach is mathematically justifiable for structures characterized by slow/fast dynamics, such as thin plates and slender beams, and has been shown to provide highly accurate results. Nevertheless, selecting the reduction basis without a priori knowledge of the full-order dynamics is a challenging task; retaining redundant m
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43

Agbemavor, Wisdom Selorm Kofi, and Elna Maria Buys. "Dynamic Interactions between Diarrhoeagenic Enteroaggregative Escherichia coli and Presumptive Probiotic Bacteria: Implications for Gastrointestinal Health." Microorganisms 11, no. 12 (2023): 2942. http://dx.doi.org/10.3390/microorganisms11122942.

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This study delves into the temporal dynamics of bacterial interactions in the gastrointestinal tract, focusing on how probiotic strains and pathogenic bacteria influence each other and human health. This research explores adhesion, competitive exclusion, displacement, and inhibition of selected diarrhoeagenic Escherichia coli (D-EAEC) and potential probiotic strains under various conditions. Key findings reveal that adhesion is time-dependent, with both D-EAEC K2 and probiotic L. plantarum FS2 showing increased adhesion over time. Surprisingly, L. plantarum FS2 outperformed D-EAEC K2 in adhesi
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44

Nedyalkov, Michail, Caroline Sultanem, and Jean-Jacque Benattar. "Contact angles of protein black foam films under dynamic and equilibrium conditions." Open Chemistry 5, no. 3 (2007): 748–65. http://dx.doi.org/10.2478/s11532-007-0014-z.

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AbstractThe contact angles of protein Newton black foam films from ALG (alpha-lactalbumin), BLG (beta-lactoglobulin) and BSA (bovine serum albumin) are measured here within. The measurements are carried out under dynamic and equilibrium conditions. For all proteins, a strong hystheresis effect of the contact angle is observed under dynamic conditions. An attempt is made to explain these results by the slow adsorption and desorption kinetics of the protein bilayers and by the dynamic structure and the rheology of the protein network forming the bubble walls. In addition, we propose a modificati
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45

Sangeeta and Arnab Bhattacherjee. "Interdomain dynamics in human Replication Protein A regulates kinetics and thermodynamics of its binding to ssDNA." PLOS ONE 18, no. 1 (2023): e0278396. http://dx.doi.org/10.1371/journal.pone.0278396.

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Human Replication Protein A (hRPA) is a multidomain protein that interacts with ssDNA intermediates to provide the latter much-needed stability during DNA metabolism and maintain genomic integrity. Although the ssDNA organization with hRPA was studied recently through experimental means, characterizing the underlying mechanism at the atomic level remains challenging because of the dynamic domain architecture of hRPA and poorly understood heterogeneity of ssDNA-protein interactions. Here, we used a computational framework, precisely tailored to capture protein-ssDNA interactions, and investigat
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46

Salmon, Wendy C., Michael C. Adams, and Clare M. Waterman-Storer. "Dual-wavelength fluorescent speckle microscopy reveals coupling of microtubule and actin movements in migrating cells." Journal of Cell Biology 158, no. 1 (2002): 31–37. http://dx.doi.org/10.1083/jcb.200203022.

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Interactions between microtubules (MTs) and filamentous actin (f-actin) are involved in directed cell locomotion, but are poorly understood. To test the hypothesis that MTs and f-actin associate with one another and affect each other's organization and dynamics, we performed time-lapse dual-wavelength spinning-disk confocal fluorescent speckle microscopy (FSM) of MTs and f-actin in migrating newt lung epithelial cells. F-actin exhibited four zones of dynamic behavior: rapid retrograde flow in the lamellipodium, slow retrograde flow in the lamellum, anterograde flow in the cell body, and no mov
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47

Qin, Huaguang, Wuxuan Hong, Zehua Qi, et al. "A Temperature-Dependent Model for Tritrophic Interactions Involving Tea Plants, Tea Green Leafhoppers and Natural Enemies." Insects 13, no. 8 (2022): 686. http://dx.doi.org/10.3390/insects13080686.

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The tea green leaf hopper, Empoasca onukii Matsuda, is a severe pest of tea plants. Volatile emissions from tea shoots infested by the tea green leafhopper may directly repel insect feeding or attract natural enemies. Many studies have been conducted on various aspects of the tritrophic relationship involving tea plants, tea green leafhoppers and natural enemies. However, mathematic models which could explain the dynamic mechanisms of this tritrophic interaction are still lacking. In the current work, we constructed a realistic and stochastic model with temperature-dependent features to charac
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48

Schmidt, C. E., A. F. Horwitz, D. A. Lauffenburger, and M. P. Sheetz. "Integrin-cytoskeletal interactions in migrating fibroblasts are dynamic, asymmetric, and regulated." Journal of Cell Biology 123, no. 4 (1993): 977–91. http://dx.doi.org/10.1083/jcb.123.4.977.

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We have used laser optical trapping and nanometer-level motion analysis to investigate the cytoskeletal associations and surface dynamics of beta 1 integrin, a cell-substrate adhesion molecule, on the dorsal surfaces of migrating fibroblast cells. A single-beam optical gradient trap (laser tweezers) was used to restrain polystyrene beads conjugated with anti-beta 1 integrin mAbs and place them at desired locations on the cell exterior. This technique was used to demonstrate a spatial difference in integrin-cytoskeleton interactions in migrating cells. We found a distinct increase in the stable
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49

Barà, Chiara, Laura Sparacino, Riccardo Pernice, et al. "Comparison of discretization strategies for the model-free information-theoretic assessment of short-term physiological interactions." Chaos: An Interdisciplinary Journal of Nonlinear Science 33, no. 3 (2023): 033127. http://dx.doi.org/10.1063/5.0140641.

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This work presents a comparison between different approaches for the model-free estimation of information-theoretic measures of the dynamic coupling between short realizations of random processes. The measures considered are the mutual information rate (MIR) between two random processes [Formula: see text] and [Formula: see text] and the terms of its decomposition evidencing either the individual entropy rates of [Formula: see text] and [Formula: see text] and their joint entropy rate, or the transfer entropies from [Formula: see text] to [Formula: see text] and from [Formula: see text] to [Fo
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50

MERCER, AARON J., and WALLACE B. THORESON. "The dynamic architecture of photoreceptor ribbon synapses: Cytoskeletal, extracellular matrix, and intramembrane proteins." Visual Neuroscience 28, no. 6 (2011): 453–71. http://dx.doi.org/10.1017/s0952523811000356.

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AbstractRod and cone photoreceptors possess ribbon synapses that assist in the transmission of graded light responses to second-order bipolar and horizontal cells of the vertebrate retina. Proper functioning of the synapse requires the juxtaposition of presynaptic release sites immediately adjacent to postsynaptic receptors. In this review, we focus on the synaptic, cytoskeletal, and extracellular matrix proteins that help to organize photoreceptor ribbon synapses in the outer plexiform layer. We examine the proteins that foster the clustering of release proteins, calcium channels, and synapti
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