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Artículos de revistas sobre el tema "Solid-state nanopore"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 26 de julio de 2025

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1

Liu, Zewen, Yifan Wang, Tao Deng, and Qi Chen. "Solid-State Nanopore-Based DNA Sequencing Technology." Journal of Nanomaterials 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/5284786.

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The solid-state nanopore-based DNA sequencing technology is becoming more and more attractive for its brand new future in gene detection field. The challenges that need to be addressed are diverse: the effective methods to detect base-specific signatures, the control of the nanopore’s size and surface properties, and the modulation of translocation velocity and behavior of the DNA molecules. Among these challenges, the realization of the high-quality nanopores with the help of modern micro/nanofabrication technologies is a crucial one. In this paper, typical technologies applied in the field o

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2

Fried, Jasper P., Jacob L. Swett, Binoy Paulose Nadappuram, et al. "In situ solid-state nanopore fabrication." Chemical Society Reviews 50, no. 8 (2021): 4974–92. http://dx.doi.org/10.1039/d0cs00924e.

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This review summarises the development of in situ solid-state nanopore fabrication techniques. These techniques are democratising solid-state nanopore research by providing rapid and accessible methods to fabricate nanopores.

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3

Ma, Aorui. "Application and Development of Biomimetic Solid-State Nanopore in Biosensing Technique." Transactions on Materials, Biotechnology and Life Sciences 7 (December 24, 2024): 303–7. https://doi.org/10.62051/zqn14b37.

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Biomimetic solid-state nanopore is a nano-level technology, which can be effectively used for many detection work, including DNA sequencing. The design of biomimetic solid-state nanopore is inspired by biological ion channels. Biomimetic solid-state nanopore displays many advantages. It can increase the processing characteristics while it can also ensure the performance of similar biological ion channels. It also exhibits controllable surface chemical properties, making biomimetic solid nanopores have more application space. When compared with traditional biosensors, biomimetic solid nanopores

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4

Wu, Kaiyan. "Solid-State Nanopores Used for the Detection of DNA Molecules." Highlights in Science, Engineering and Technology 73 (November 29, 2023): 302–6. http://dx.doi.org/10.54097/hset.v73i.12996.

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Solid-state nanopore is crucial in dection of DNA molescules. DNA is made up of two antiparallel strands of polynucleotides. They are joined together by hydrogen bonds between complementary base pairs. The DNA structures are essential for the ability of genetic carrier to control gene expression, promote DNA recombination, and enhance mutagenesis. There are many ways to do DNA testing. Among these methods, nanopore have relatively small size which allows single-molecule detection. It is also less expensive. There are two kinds of nanopores, which are solid-state nanopore and biological nanopor

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5

Lei, Xin, Jiayan Zhang, Hao Hong, Zhishan Yuan, and Zewen Liu. "Controllable Shrinking Fabrication of Solid-State Nanopores." Micromachines 13, no. 6 (2022): 923. http://dx.doi.org/10.3390/mi13060923.

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Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy. Despite the most use of naturally biological nanopores before, solid-state nanopores are widely developed with strong robustness, controllable sizes and geometries, a wide range of materials available, as well as flexible manufacturing. Therefore, various techniques typically based on focused ion beam or electron beam have been explored to drill nanopores directly on free-standing nanofilms. To further reduce and sculpt the pore size and sh

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6

Eggenberger, Olivia M., Cuifeng Ying, and Michael Mayer. "Surface coatings for solid-state nanopores." Nanoscale 11, no. 42 (2019): 19636–57. http://dx.doi.org/10.1039/c9nr05367k.

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7

Takai, Natsumi, Kan Shoji, Tei Maki, and Ryuji Kawano. "Simple Fabrication of Solid-State Nanopores on a Carbon Film." Micromachines 12, no. 9 (2021): 1135. http://dx.doi.org/10.3390/mi12091135.

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Solid-state nanopores are widely used as a platform for stochastic nanopore sensing because they can provide better robustness, controllable pore size, and higher integrability than biological nanopores. However, the fabrication procedures, including thin film preparation and nanopore formation, require advanced micro-and nano-fabrication techniques. Here, we describe the simple fabrication of solid-state nanopores in a commercially available material: a flat thin carbon film-coated micro-grid for a transmission electron microscope (TEM). We attempted two general methods for nanopore fabricati

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8

Liu, Li Ping, Hong Wen Wu, Yang Xuan, et al. "Study on the Size Shrinking and Shape Changing of Solid-State Nanopores." Advanced Materials Research 189-193 (February 2011): 3218–21. http://dx.doi.org/10.4028/www.scientific.net/amr.189-193.3218.

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Nanopores etched in the solid-state membranes have become the hotpot of nanotechnology research. Various methods for fabricating solid-state nanopores have been developed and reported, but the fabrication of nanopore is also a difficult challenge. In this paper, we milled nanopores of different sizes in the free-stand and low-stress solid-state membranes. And then the area around nanopores were scanned with the diffused ion beam, we found that the sediment around will melt and the shape of the nanopore becomes circular.

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9

Cheng, Peng, Candong Zhao, Qinjie Pan, et al. "Detection of Biomolecules Using Solid-State Nanopores Fabricated by Controlled Dielectric Breakdown." Sensors 24, no. 8 (2024): 2420. http://dx.doi.org/10.3390/s24082420.

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Nanopore sensor technology is widely used in biomolecular detection due to its advantages of low cost and easy operation. In a variety of nanopore manufacturing methods, controlled dielectric breakdown has the advantages of a simple manufacturing process and low cost under the premise of ensuring detection performance. In this paper, we have made enhancements to the applied pulses in controlled dielectric breakdown and utilized the improved dielectric breakdown technique to fabricate silicon nitride nanopores with diameters of 5 to 15 nm. Our improved fabrication method offers the advantage of

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10

Soni, Gautam V., and Amit Meller. "Progress toward Ultrafast DNA Sequencing Using Solid-State Nanopores." Clinical Chemistry 53, no. 11 (2007): 1996–2001. http://dx.doi.org/10.1373/clinchem.2007.091231.

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Abstract Background: Measurements of the ionic current flowing through nanometer-scale pores (nanopores) have been used to analyze single DNA and RNA molecules, with the ultimate goal of achieving ultrafast DNA sequencing. However, attempts at purely electronic measurements have not achieved the signal contrast required for single nucleotide differentiation. In this report we propose a novel method of optical detection of DNA sequence translocating through a nanopore. Methods: Each base of the target DNA sequence is 1st mapped onto a 2-unit code, 2 10-bp nucleotide sequence, by biochemical con

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11

Jones, Peter D., and Michael Mierzejewski. "Integration of solid-state nanopore arrays via dry bonding to photostructured microfluidic networks." Journal of Micromechanics and Microengineering 35, no. 4 (2025): 045003. https://doi.org/10.1088/1361-6439/adba71.

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Abstract The integration and parallelization of nanopore sensors are essential for improving the throughput of nanopore measurements. Solid-state nanopores traditionally have been used in isolation, which prevents the realization of their full potential in applications. In this study, we present the microfluidic integration of an array of 30 solid-state nanopores, which, to our knowledge, is the highest number reported to date. Our microfluidic network was fabricated using high-resolution epoxy photoresists, and the solid-state membranes were bonded through a dry process using complementary su

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12

Ivanov, Yuri D., Alexander N. Ableev, Ivan D. Shumov, et al. "Registration of Functioning of a Single Horseradish Peroxidase Macromolecule with a Solid-State Nanopore." International Journal of Molecular Sciences 24, no. 21 (2023): 15636. http://dx.doi.org/10.3390/ijms242115636.

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Currently, nanopore-based technology for the determination of the functional activity of single enzyme molecules continues its development. The use of natural nanopores for studying single enzyme molecules is known. At that, the approach utilizing artificial solid-state nanopores is also promising but still understudied. Herein, we demonstrate the use of a nanotechnology-based approach for the investigation of the enzymatic activity of a single molecule of horseradish peroxidase with a solid-state nanopore. The artificial 5 nm solid-state nanopore has been formed in a 40 nm thick silicon nitri

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13

Liu, Li Ping, Hong Wen Wu, Hang Liu, Jing Lin Kong, and Quan Jun Liu. "Distribution Time of Gold Nanoparticles Pass through the Solid State Nanopore in Deionized Water." Advanced Materials Research 646 (January 2013): 67–71. http://dx.doi.org/10.4028/www.scientific.net/amr.646.67.

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Nanopore has the proming to be used as the detection senser for the single molecule at single molecular level or the nanoparticles in different meterials. The diameters of the nanopores can be changed in a large rang with the increasing fabrication technology. For this case, the nanopore could be used as particles‘ sizes senser. We used 15nm gold nanoparticles as exsamples to analyze the effects of nanopore/nanoparticle ratio in deionized water. In the detection experiments, we found that the gold nanoparticles would pass through the nanopore in different behaves. Besides, the diameters of the

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14

Restrepo-Pérez, Laura, Shalini John, Aleksei Aksimentiev, Chirlmin Joo, and Cees Dekker. "SDS-assisted protein transport through solid-state nanopores." Nanoscale 9, no. 32 (2017): 11685–93. http://dx.doi.org/10.1039/c7nr02450a.

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Using nanopores for single-molecule sequencing of proteins faces multiple challenges. Here, we investigate the utility of SDS (Sodium Dodecyl Sulfate) to unfold proteins for solid-state nanopore traslocations.

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15

Rahman, Mahmudur, Mohammad Julker Neyen Sampad, Aaron Hawkins, and Holger Schmidt. "Recent advances in integrated solid-state nanopore sensors." Lab on a Chip 21, no. 16 (2021): 3030–52. http://dx.doi.org/10.1039/d1lc00294e.

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Nanopores are powerful single molecule sensors that have a wide range of applications from single molecule biophysics to medical diagnostics. This review covers all aspects of nanopore sensor integration into increasingly complex lab-on-chip systems.

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16

Xue, Liang, Hirohito Yamazaki, Ren Ren, Meni Wanunu, Aleksandar P. Ivanov, and Joshua B. Edel. "Solid-state nanopore sensors." Nature Reviews Materials 5, no. 12 (2020): 931–51. http://dx.doi.org/10.1038/s41578-020-0229-6.

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17

Sawafta, Furat, Bason Clancy, Autumn T. Carlsen, Martin Huber, and Adam R. Hall. "Solid-state nanopores and nanopore arrays optimized for optical detection." Nanoscale 6, no. 12 (2014): 6991–96. http://dx.doi.org/10.1039/c4nr00305e.

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Controllable reduction of the local fluorescence around solid-state nanopores and nanopore arrays enables optical recognition of molecular translocations and a route towards massively-parallel detection.

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18

Acar, Elif Turker, Steven F. Buchsbaum, Cody Combs, Francesco Fornasiero, and Zuzanna S. Siwy. "Biomimetic potassium-selective nanopores." Science Advances 5, no. 2 (2019): eaav2568. http://dx.doi.org/10.1126/sciadv.aav2568.

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Reproducing the exquisite ion selectivity displayed by biological ion channels in artificial nanopore systems has proven to be one of the most challenging tasks undertaken by the nanopore community, yet a successful achievement of this goal offers immense technological potential. Here, we show a strategy to design solid-state nanopores that selectively transport potassium ions and show negligible conductance for sodium ions. The nanopores contain walls decorated with 4′-aminobenzo-18-crown-6 ether and single-stranded DNA (ssDNA) molecules located at one pore entrance. The ionic selectivity ste

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19

Zhong, Yunxi. "Recent Application of Nanopores in the Detection of Small Organic Molecules." Transactions on Materials, Biotechnology and Life Sciences 4 (August 29, 2024): 76–81. http://dx.doi.org/10.62051/qmxc3d44.

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Nanopore sensors have become a useful tool for detecting small organic molecules, which provides more and more accurate options than traditional analytical techniques. This review outlines and compare the application of various emerging nanopore sensors, which includes solid-state nanopore (silicon nitride and MsO2) and non-solid-state nanopore (α-hemolysin nanopore, aerolysin nanopore, MspA and so on), to identify various organic molecules, including amino acids, nucleotides monosaccharides and others. By taking advantage of the unique current signatures that molecules penerate through nanopo

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20

Zhang, Yin, Dexian Ma, Zengdao Gu, Lijian Zhan, and Jingjie Sha. "Fast Fabrication of Solid-State Nanopores for DNA Molecule Analysis." Nanomaterials 11, no. 9 (2021): 2450. http://dx.doi.org/10.3390/nano11092450.

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Solid-state nanopores have been developed as a prominent tool for single molecule analysis in versatile applications. Although controlled dielectric breakdown (CDB) is the most accessible method for a single nanopore fabrication, it is still necessary to improve the fabrication efficiency and avoid the generation of multiple nanopores. In this work, we treated the SiNx membranes in the air–plasma before the CDB process, which shortened the time-to-pore-formation by orders of magnitude. λ-DNA translocation experiments validated the functionality of the pore and substantiated the presence of onl

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21

Shi, Xin, Rui Gao, Yi-Lun Ying, Wei Si, Yunfei Chen, and Yi-Tao Long. "An integrated system for optical and electrical detection of single molecules/particles inside a solid-state nanopore." Faraday Discussions 184 (2015): 85–99. http://dx.doi.org/10.1039/c5fd00060b.

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Nanopore techniques have proven to be useful tools for single-molecule detection. The combination of optical detection and ionic current measurements enables a new possibility for the parallel readout of multiple nanopores without complex nanofluidics and embedded electrodes. In this study, we developed a new integrated system for the label-free optical and electrical detection of single molecules based on a metal-coated nanopore. The entire system, containing a dark-field microscopy system and an ultralow current detection system with high temporal resolution, was designed and fabricated. An

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22

Xi, Guohao, Yuan Ye, Lulu Wang, et al. "Spatial conformation measurement of gold nanorods translocated through a solid-state nanopore." Materials Express 10, no. 10 (2020): 1732–39. http://dx.doi.org/10.1166/mex.2020.1836.

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The solid-state nanopore has been developed as a powerful biosensor to detect individual molecules and nanoparticles. The operational principle of the technique was to determine the volume, concentration, and zeta potential of the particles from the electrical signals as nanoparticles passing through the pore. Here, gold nanorod samples were used to measure the dynamic translocation process though a nano channel. Gold nanorods have a high throughput in silicon nitride nanopore sensing because of their positive charge characteristics. Meanwhile, a set of varied shapes of nanorods was modeled in

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23

Wang, Lei, Wen Yuan Zhao, Dan Mo, and Quan Jun Liu. "Solid-State Nanopores for Nanoparticle Sensing." Applied Mechanics and Materials 618 (August 2014): 8–13. http://dx.doi.org/10.4028/www.scientific.net/amm.618.8.

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In recent years, single particle detection techniques based on driving nanoparticles through nanoscopic pores with a voltage or pressure had been the subject of numerous studies. Since particles with high charge, such as DNA and proteins, have been widely used for research, there was little information about the translocation behavior of nanosized particles which with low charge. However, nanoparticles include virus and colloids are important samples for nanopore sensing technology. In this study, we employed the solid-state nanopore to sense nanoparticles as fundamental study. Nanopore with d

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24

Healy, Ken, Birgitta Schiedt, and Alan P. Morrison. "Solid-state nanopore technologies for nanopore-based DNA analysis." Nanomedicine 2, no. 6 (2007): 875–97. http://dx.doi.org/10.2217/17435889.2.6.875.

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25

Ma, Jian, Qingyu Zeng, Lijian Zhan, Jingwen Mo, Yan Zhang, and Zhonghua Ni. "Power Generation from Salinity Gradient by Reverse Electrodialysis in Silicon Nitride Nanopores." Nano 15, no. 11 (2020): 2050148. http://dx.doi.org/10.1142/s1793292020501489.

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Solid-state nanopores have shown great potential in investigating salinity gradient energy generation as a renewable power generator. In this work, various diameter silicon nitride (Si3N[Formula: see text] nanopores were fabricated to investigate the power generation between two potassium chloride solutions with different concentration gradient ratios by reverse electrodialysis. The maximal estimated power density of a Si3N4 nanopore measured experimentally can be high to 16[Formula: see text]649Wm[Formula: see text]. To compare with the single Si3N4 nanopore, multiple nanopores array has also

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26

Fu, Jiye, Linlin Wu, Yi Qiao, Jing Tu, and Zuhong Lu. "Microfluidic Systems Applied in Solid-State Nanopore Sensors." Micromachines 11, no. 3 (2020): 332. http://dx.doi.org/10.3390/mi11030332.

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Microfluidic system, as a kind of miniature integrated operating platform, has been applied to solid-state nanopore sensors after many years of experimental study. In the process of introducing microfluidic into solid-state nanopore sensors, many novel device structures are designed due to the abundance of analytes and the diversity of detection methods. Here we review the fundamental setup of nanopore-based microfluidic systems and the developments and advancements that have been taking place in the field. The microfluidic systems with a multichannel strategy to elevate the throughput and eff

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27

Ying, Cuifeng, Tianji Ma, Lei Xu, and Mohsen Rahmani. "Localized Nanopore Fabrication via Controlled Breakdown." Nanomaterials 12, no. 14 (2022): 2384. http://dx.doi.org/10.3390/nano12142384.

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Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications. Solid-state nanopores offer the potential to integrate nanopore sensing with other technologies such as field-effect transistors (FETs), optics, plasmonics, and microfluidics, thereby attracting attention to the development of commercial instruments for diagnostics and healthcare applications. Stable nanopores with ideal dimensions are particularly critical for nanopore sensors to be integrated into other sensing de

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28

Acharjee, Mitu C., Haopeng Li, Ryan Rollings, Bo Ma, Steve Tung, and Jiali Li. "Tau and tubulin protein aggregation characterization by solid-state nanopore method and atomic force microscopy." Journal of Applied Physics 133, no. 2 (2023): 024701. http://dx.doi.org/10.1063/5.0123688.

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In this study, a silicon nitride nanopore-based sensing system was used to measure tau and tubulin monomers and their aggregations in salt solution at a single molecule level. Nanopores (6–30 nm) were fabricated on silicon nitride membranes supported by silicon substrates using a combination of focused ion beam milling and ion beam sculpting. When a charged protein molecule in the salt solution passes through a nanopore driven by an applied voltage, the protein molecule increases pore resistivity, which induces an ionic current drop that can be measured. The current drop amplitude is directly

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29

Men, Xinyao. "Development and Application of Nanopore Technology in Biosensing and Diagnostics." Theoretical and Natural Science 93, no. 1 (2025): 113–17. https://doi.org/10.54254/2753-8818/2025.22975.

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Nanopore technology has emerged as a powerful tool for biosensing, enabling real-time, single-molecule detection with high sensitivity and specificity. Over the past few decades, this technology has evolved significantly, transitioning from biological nanopores to solid-state nanopores, hybrid nanopores, and two-dimensional (2D) material nanopores, integrating advances in materials science, bioengineering, and computational modeling. The primary advantages of nanopore sensors include their ability to analyze nucleic acids, proteins, and small molecules without requiring labeling, making them i

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30

Yuan, Zhishan, Yanbang Lin, Jieming Hu, and Chengyong Wang. "Controllable Fabrication of Sub-10 nm Graphene Nanopores via Helium Ion Microscopy and DNA Detection." Biosensors 14, no. 4 (2024): 158. http://dx.doi.org/10.3390/bios14040158.

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Solid-state nanopores have become a prominent tool in the field of single-molecule detection. Conventional solid-state nanopores are thick, which affects the spatial resolution of the detection results. Graphene is the thinnest 2D material and has the highest spatial detection resolution. In this study, a graphene membrane chip was fabricated by combining a MEMS process with a 2D material wet transfer process. Raman spectroscopy was used to assess the quality of graphene after the transfer. The mechanism behind the influence of the processing dose and residence time of the helium ion beam on t

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31

Haq, Muhammad Refatul, Bong Jae Lee, and Jungchul Lee. "Solid-State Nanopore for Molecular Detection." International Journal of Precision Engineering and Manufacturing 22, no. 12 (2021): 2001–26. http://dx.doi.org/10.1007/s12541-021-00590-2.

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32

Ghosal, Sandip, John D. Sherwood, and Hsueh-Chia Chang. "Solid-state nanopore hydrodynamics and transport." Biomicrofluidics 13, no. 1 (2019): 011301. http://dx.doi.org/10.1063/1.5083913.

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33

Rosenstein, Jacob, Meni Wanunu, Marija Drndic, and Kenneth L. Shepard. "High-Bandwidth Solid-State Nanopore Sensors." Biophysical Journal 102, no. 3 (2012): 428a. http://dx.doi.org/10.1016/j.bpj.2011.11.2346.

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34

Xue, Liang, Hirohito Yamazaki, Ren Ren, Meni Wanunu, Aleksandar P. Ivanov, and Joshua B. Edel. "Author Correction: Solid-state nanopore sensors." Nature Reviews Materials 5, no. 12 (2020): 952. http://dx.doi.org/10.1038/s41578-020-00256-x.

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Zhao, Xiaojing, Yue Zhao, Yunsheng Deng, et al. "DNA translocation through solid-state nanopore." Journal of Micro-Bio Robotics 14, no. 1-2 (2018): 35–40. http://dx.doi.org/10.1007/s12213-018-0104-3.

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36

Ji, Anping, Bo Wang, Guofeng Xia, Jinjie Luo, and Zhenghua Deng. "Effective Modulation of Ion Mobility through Solid-State Single-Digit Nanopores." Nanomaterials 12, no. 22 (2022): 3946. http://dx.doi.org/10.3390/nano12223946.

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Many experimental studies have proved that ion dynamics in a single-digit nanopore with dimensions comparable to the Debye length deviate from the bulk values, but we still have critical knowledge gaps in our understanding of ion transport in nanoconfinement. For many energy devices and sensor designs of nanoporous materials, ion mobility is a key parameter for the performance of nanofluidic equipment. However, investigating ion mobility remains an experimental challenge. This study experimentally investigated the monovalent ion dynamics of single-digit nanopores from the perspective of ionic

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37

Tang, Zhuoming. "Principles of Biomimetic solid-state nanopores and the application to biosensors." Highlights in Science, Engineering and Technology 73 (November 29, 2023): 289–93. http://dx.doi.org/10.54097/hset.v73i.12991.

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The wide application of biomimetic solid-state nanopores in biosensors has made them a high-profile research area. It can be applied in several fields such as genomics, proteomics, biomedicine, and environmental monitoring. Bionic solid-state nanopores have demonstrated the capability to detect biomolecules and creatures, including proteins, nucleic acids, cells, and microbes, with a notable degree of sensitivity and selectivity. Biomimetic solid-state nanopores offer several advantages over conventional biosensors. An innovative kind of biosensor is called biomimetic solid state nanopores. Th

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38

Park, Kyeong-Beom, Hyung-Jun Kim, Yun-Ho Kang, et al. "Highly reliable and low-noise solid-state nanopores with an atomic layer deposited ZnO membrane on a quartz substrate." Nanoscale 9, no. 47 (2017): 18772–80. http://dx.doi.org/10.1039/c7nr05755e.

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We present a fabrication scheme for a ZnO nanopore membrane directly deposited on top of a quartz substrate by atomic layer deposition (ALD) and investigate the characteristics of DNA translocation through the nanopores.

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39

Yan, Han, Zhen Zhang, Ting Weng, et al. "Recognition of Bimolecular Logic Operation Pattern Based on a Solid-State Nanopore." Sensors 21, no. 1 (2020): 33. http://dx.doi.org/10.3390/s21010033.

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Nanopores have a unique advantage for detecting biomolecules in a label-free fashion, such as DNA that can be synthesized into specific structures to perform computations. This method has been considered for the detection of diseased molecules. Here, we propose a novel marker molecule detection method based on DNA logic gate by deciphering a variable DNA tetrahedron structure using a nanopore. We designed two types of probes containing a tetrahedron and a single-strand DNA tail which paired with different parts of the target molecule. In the presence of the target, the two probes formed a doub

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40

Mussi, V., P. Fanzio, L. Repetto, et al. "DNA-functionalized solid state nanopore for biosensing." Nanotechnology 21, no. 14 (2010): 145102. http://dx.doi.org/10.1088/0957-4484/21/14/145102.

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41

Iqbal, Samir M., Demir Akin, and Rashid Bashir. "Solid-state nanopore channels with DNA selectivity." Nature Nanotechnology 2, no. 4 (2007): 243–48. http://dx.doi.org/10.1038/nnano.2007.78.

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42

Raveendran, Mukhil, Anna Rose Leach, Tayah Hopes, Julie L. Aspden, and Paolo Actis. "Ribosome Fingerprinting with a Solid-State Nanopore." ACS Sensors 5, no. 11 (2020): 3533–39. http://dx.doi.org/10.1021/acssensors.0c01642.

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43

Deng, Tao, Mengwei Li, Yifan Wang, and Zewen Liu. "Development of solid-state nanopore fabrication technologies." Science Bulletin 60, no. 3 (2015): 304–19. http://dx.doi.org/10.1007/s11434-014-0705-8.

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44

Hall, Adam R., and Dhruba Jyoti Basu Roy. "Solid-State Nanopore Detection of Hydrophobic Proteins." Biophysical Journal 112, no. 3 (2017): 155a. http://dx.doi.org/10.1016/j.bpj.2016.11.849.

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Vlassarev, Dimitar M., and Jene A. Golovchenko. "Trapping DNA near a Solid-State Nanopore." Biophysical Journal 103, no. 2 (2012): 352–56. http://dx.doi.org/10.1016/j.bpj.2012.06.008.

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46

Ying, Song, Lei Wang, and Wen Yuan Zhao. "The Noise Analysis of Fluid Systemsin Solid-State Nanopore Sensors." Applied Mechanics and Materials 419 (October 2013): 517–20. http://dx.doi.org/10.4028/www.scientific.net/amm.419.517.

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Resumen

The solid-state nanopore sensor offers a versatile platform for the rapid, label-free electrical detection and analysis of single molecules, especially on DNA sequencing. However, the overall signal-to-noise ratio (SNA) is a major challenge in sequencing applications. In our work, two different fluid systems made by metal and plexiglass have been designed to improve the signal to noise ratio of the solid-state nanopore sensor. From the measurements on the noise power spectra with a variety of conditions, it is found that plexiglass fluid system coupled with shielding box produces a good qualit

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47

Zhu, Zhentong, Ruiping Wu, and Bingling Li. "Exploration of solid-state nanopores in characterizing reaction mixtures generated from a catalytic DNA assembly circuit." Chemical Science 10, no. 7 (2019): 1953–61. http://dx.doi.org/10.1039/c8sc04875d.

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We adapt a solid-state nanopore for analyzing DNA assembly mixtures, which is usually a tougher task for either traditional characterization methods or nanopores themselves. A trigger induced nucleic acid amplifier, SP-CHA, is designed as a model. We propose an electrophoresis-gel like, but homogeneous, quantitative method that can comprehensively profile the “base-pair distribution” of SP-CHA concatemer mixtures.

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48

Roy, Dhrubajyoti Basu, and Adam R. Hall. "Solid-state nanopore analysis of alcohol-soluble molecules." Analyst 142, no. 10 (2017): 1676–81. http://dx.doi.org/10.1039/c7an00022g.

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49

Shepherd, Britney A., Md Rubayat-E. Tanjil, Yunjo Jeong, Bilgenur Baloğlu, Jingqiu Liao, and Michael Cai Wang. "Ångström- and Nano-scale Pore-Based Nucleic Acid Sequencing of Current and Emergent Pathogens." MRS Advances 5, no. 56 (2020): 2889–906. http://dx.doi.org/10.1557/adv.2020.402.

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AbstractState-of-the-art nanopore sequencing enables rapid and real-time identification of novel pathogens, which has wide application in various research areas and is an emerging diagnostic tool for infectious diseases including COVID-19. Nanopore translocation enables de novo sequencing with long reads (> 10 kb) of novel genomes, which has advantages over existing short-read sequencing technologies. Biological nanopore sequencing has already achieved success as a technology platform but it is sensitive to empirical factors such as pH and temperature. Alternatively, ångström- and nano-scal

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50

Spitzberg, Joshua D., Xander F. van Kooten, Moran Bercovici, and Amit Meller. "Microfluidic device for coupling isotachophoretic sample focusing with nanopore single-molecule sensing." Nanoscale 12, no. 34 (2020): 17805–11. http://dx.doi.org/10.1039/d0nr05000h.

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