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Artículos de revistas sobre el tema "Structural virology"

Autor: Grafiati

Publicado: 14 de diciembre de 2024

Última modificación: 31 de julio de 2025

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1

Agbandje-McKenna, Mavis, and Richard Kuhn. "Current opinion in virology: structural virology." Current Opinion in Virology 1, no. 2 (2011): 81–83. http://dx.doi.org/10.1016/j.coviro.2011.07.001.

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2

Stuart, David. "Changing times in structural virology." Acta Crystallographica Section A Foundations and Advances 75, a2 (2019): e18-e18. http://dx.doi.org/10.1107/s205327331909538x.

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3

Sousa, Rui. "Structural Virology 4. T7 RNA Polymerase." Uirusu 51, no. 1 (2001): 81–94. http://dx.doi.org/10.2222/jsv.51.81.

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4

Shepherd, C. M. "VIPERdb: a relational database for structural virology." Nucleic Acids Research 34, no. 90001 (2006): D386—D389. http://dx.doi.org/10.1093/nar/gkj032.

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5

Kiss, Bálint, Dorottya Mudra, György Török, et al. "Single-particle virology." Biophysical Reviews 12, no. 5 (2020): 1141–54. http://dx.doi.org/10.1007/s12551-020-00747-9.

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Abstract The development of advanced experimental methodologies, such as optical tweezers, scanning-probe and super-resolved optical microscopies, has led to the evolution of single-molecule biophysics, a field of science that allows direct access to the mechanistic detail of biomolecular structure and function. The extension of single-molecule methods to the investigation of particles such as viruses permits unprecedented insights into the behavior of supramolecular assemblies. Here we address the scope of viral exploration at the level of individual particles. In an era of increased awarenes

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6

Meier, Kristina, Sigurdur R. Thorkelsson, Emmanuelle R. J. Quemin, and Maria Rosenthal. "Hantavirus Replication Cycle—An Updated Structural Virology Perspective." Viruses 13, no. 8 (2021): 1561. http://dx.doi.org/10.3390/v13081561.

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Hantaviruses infect a wide range of hosts including insectivores and rodents and can also cause zoonotic infections in humans, which can lead to severe disease with possible fatal outcomes. Hantavirus outbreaks are usually linked to the population dynamics of the host animals and their habitats being in close proximity to humans, which is becoming increasingly important in a globalized world. Currently there is neither an approved vaccine nor a specific and effective antiviral treatment available for use in humans. Hantaviruses belong to the order Bunyavirales with a tri-segmented negative-sen

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7

Rossmann, Michael G. "Virus crystallography and structural virology: a personal perspective." Crystallography Reviews 21, no. 1-2 (2014): 57–102. http://dx.doi.org/10.1080/0889311x.2014.957282.

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8

Khayat, Reza. "Call for Papers: Special Issue on Structural Virology." Viral Immunology 32, no. 10 (2019): 415. http://dx.doi.org/10.1089/vim.2019.29046.cfp.

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9

Schoehn, Guy, Florian Chenavier, and Thibaut Crépin. "Advances in Structural Virology via Cryo-EM in 2022." Viruses 15, no. 6 (2023): 1315. http://dx.doi.org/10.3390/v15061315.

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10

Handa, Tanuj, Ankita Saha, Aarthi Narayanan, et al. "Structural Virology: The Key Determinants in Development of Antiviral Therapeutics." Viruses 17, no. 3 (2025): 417. https://doi.org/10.3390/v17030417.

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Structural virology has emerged as the foundation for the development of effective antiviral therapeutics. It is pivotal in providing crucial insights into the three-dimensional frame of viruses and viral proteins at atomic-level or near-atomic-level resolution. Structure-based assessment of viral components, including capsids, envelope proteins, replication machinery, and host interaction interfaces, is instrumental in unraveling the multiplex mechanisms of viral infection, replication, and pathogenesis. The structural elucidation of viral enzymes, including proteases, polymerases, and integr

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11

Doane, Frances W. "Immunoelectron Microscopy in Diagnostic Virology." Ultrastructural Pathology 11, no. 5-6 (1987): 681–85. http://dx.doi.org/10.3109/01913128709048454.

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12

Porat-Dahlerbruch, Gal, Amir Goldbourt, and Tatyana Polenova. "Virus Structures and Dynamics by Magic-Angle Spinning NMR." Annual Review of Virology 8, no. 1 (2021): 219–37. http://dx.doi.org/10.1146/annurev-virology-011921-064653.

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Techniques for atomic-resolution structural biology have evolved during the past several decades. Breakthroughs in instrumentation, sample preparation, and data analysis that occurred in the past decade have enabled characterization of viruses with an unprecedented level of detail. Here we review the recent advances in magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy for structural analysis of viruses and viral assemblies. MAS NMR is a powerful method that yields information on 3D structures and dynamics in a broad range of experimental conditions. After a brief introdu

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13

Yadav, Sandeep Kumar. "Electron Microscopy for Structural Determination and Analysis of Viruses." Biotechnology Kiosk 4, no. 2 (2022): 12–25. http://dx.doi.org/10.37756/bk.22.4.2.2.

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Viruses are known to be associated with large-scale, dynamic conformational changes that take place to facilitate cell entry and genome delivery. It is also known that a replication machinery is involved in the advanced stage of the infectious cycle that enables to read and synthesize nucleic acid strands. This process results in the generation of new copies of genetic material. In this process, the function of structural proteins helps to assemble and package the appropriate contents to produce new infectious particles. Lately, there has been a great deal of research interest on structural el

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14

Chaley, M. B., and V. A. Kutyrkin. "Typological Approaches to Recognizing Genus and Subgenus of Coronaviruses by Structural and Non-Structural Genes." Mathematical Biology and Bioinformatics 19, no. 2 (2025): 593–606. https://doi.org/10.17537/2024.19.593.

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Owing to rapid growth of data on viral genomes in the result of metagenomic researches, bioinformatics and virology are increasingly interacting. There is even the term viral informatics, implying the existence of a whole complex of the databases, knowledge databases about the viruses and software tools for working with them. Among the problems of bioinformatics in virology, it was earlier pointed out to annotation of viral genomes. In the present work on the example of recognizing of subgenus and genus of the coronaviruses a fairly simple and effective typological approach to virus annotation

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15

Bengs, Suvi, Jane Marttila, Petri Susi, and Jorma Ilonen. "Elicitation of T-cell responses by structural and non-structural proteins of coxsackievirus B4." Journal of General Virology 96, no. 2 (2015): 322–30. http://dx.doi.org/10.1099/vir.0.069062-0.

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16

Venkatakrishnan, Balasubramanian, and Adam Zlotnick. "The Structural Biology of Hepatitis B Virus: Form and Function." Annual Review of Virology 3, no. 1 (2016): 429–51. http://dx.doi.org/10.1146/annurev-virology-110615-042238.

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17

Carrillo-Tripp, M., C. M. Shepherd, I. A. Borelli, et al. "VIPERdb2: an enhanced and web API enabled relational database for structural virology." Nucleic Acids Research 37, Database (2009): D436—D442. http://dx.doi.org/10.1093/nar/gkn840.

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18

Dowd, Kimberly A., and Theodore C. Pierson. "The Many Faces of a Dynamic Virion: Implications of Viral Breathing on Flavivirus Biology and Immunogenicity." Annual Review of Virology 5, no. 1 (2018): 185–207. http://dx.doi.org/10.1146/annurev-virology-092917-043300.

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Flaviviruses are arthropod-borne RNA viruses that are a significant threat to global health due to their widespread distribution, ability to cause severe disease in humans, and capacity for explosive spread following introduction into new regions. Members of this genus include dengue, tick-borne encephalitis, yellow fever, and Zika viruses. Vaccination has been a highly successful means to control flaviviruses, and neutralizing antibodies are an important component of a protective immune response. High-resolution structures of flavivirus structural proteins and virions, alone and in complex wi

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19

Lukashev, Alexander N., Vasilii A. Lashkevich, Olga E. Ivanova, Galina A. Koroleva, Ari E. Hinkkanen, and Jorma Ilonen. "Recombination in circulating Human enterovirus B: independent evolution of structural and non-structural genome regions." Journal of General Virology 86, no. 12 (2005): 3281–90. http://dx.doi.org/10.1099/vir.0.81264-0.

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The complete nucleotide sequences of eight Human enterovirus B (HEV-B) strains were determined, representing five serotypes, E6, E7, E11, CVB3 and CVB5, which were isolated in the former Soviet Union between 1998 and 2002. All strains were mosaic recombinants and only the VP2–VP3–VP1 genome region was similar to that of the corresponding prototype HEV-B strains. In seven of the eight strains studied, the 2C–3D genome region was most similar to the prototype E30, EV74 and EV75 strains, whilst the remaining strain was most similar to the prototype E1 and E9 strains in the non-structural protein

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20

Subramanian, Sundharraman, Kristin N. Parent, and Sarah M. Doore. "Ecology, Structure, and Evolution of Shigella Phages." Annual Review of Virology 7, no. 1 (2020): 121–41. http://dx.doi.org/10.1146/annurev-virology-010320-052547.

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Numerous bacteriophages—viruses of bacteria, also known as phages—have been described for hundreds of bacterial species. The Gram-negative Shigella species are close relatives of Escherichia coli, yet relatively few previously described phages appear to exclusively infect this genus. Recent efforts to isolate Shigella phages have indicated these viruses are surprisingly abundant in the environment and have distinct genomic and structural properties. In addition, at least one model system used for experimental evolution studies has revealed a unique mechanism for developing faster infection cyc

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21

Quemin, Emmanuelle R. J., Emily A. Machala, Benjamin Vollmer, et al. "Cellular Electron Cryo-Tomography to Study Virus-Host Interactions." Annual Review of Virology 7, no. 1 (2020): 239–62. http://dx.doi.org/10.1146/annurev-virology-021920-115935.

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Viruses are obligatory intracellular parasites that reprogram host cells upon infection to produce viral progeny. Here, we review recent structural insights into virus-host interactions in bacteria, archaea, and eukaryotes unveiled by cellular electron cryo-tomography (cryoET). This advanced three-dimensional imaging technique of vitreous samples in near-native state has matured over the past two decades and proven powerful in revealing molecular mechanisms underlying viral replication. Initial studies were restricted to cell peripheries and typically focused on early infection steps, analyzin

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22

Young, Megan, Harry Crook, Janet Scott, and Paul Edison. "Covid-19: virology, variants, and vaccines." BMJ Medicine 1, no. 1 (2022): e000040. http://dx.doi.org/10.1136/bmjmed-2021-000040.

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As of 25 January 2022, over 349 million individuals have received a confirmed diagnosis of covid-19, with over 5.59 million confirmed deaths associated with the SARS-CoV-2 virus. The covid-19 pandemic has prompted an extensive global effort to study the molecular evolution of the virus and develop vaccines to prevent its spread. Although rigorous determination of SARS-CoV-2 infectivity remains elusive, owing to the continuous evolution of the virus, steps have been made to understand its genome, structure, and emerging genetic mutations. The SARS-CoV-2 genome is composed of several open readin

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23

Huang, Kuan-Ying A. "Structural basis for neutralization of enterovirus." Current Opinion in Virology 51 (December 2021): 199–206. http://dx.doi.org/10.1016/j.coviro.2021.10.006.

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24

Li, Xiang, Lavanya Krishnan, Peter Cherepanov, and Alan Engelman. "Structural biology of retroviral DNA integration." Virology 411, no. 2 (2011): 194–205. http://dx.doi.org/10.1016/j.virol.2010.12.008.

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25

Mattei, Simone, Florian KM Schur, and John AG Briggs. "Retrovirus maturation—an extraordinary structural transformation." Current Opinion in Virology 18 (June 2016): 27–35. http://dx.doi.org/10.1016/j.coviro.2016.02.008.

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26

Fukuhara, Hideo, Mwila Hilton Mwaba, and Katsumi Maenaka. "Structural characteristics of measles virus entry." Current Opinion in Virology 41 (April 2020): 52–58. http://dx.doi.org/10.1016/j.coviro.2020.04.002.

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27

Conte, Maria R., and Stephen Matthews. "Retroviral Matrix Proteins: A Structural Perspective." Virology 246, no. 2 (1998): 191–98. http://dx.doi.org/10.1006/viro.1998.9206.

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28

Armengol, Elisenda, Karl-Heinz Wiesmüller, Daniel Wienhold, et al. "Identification of T-cell epitopes in the structural and non-structural proteins of classical swine fever virus." Journal of General Virology 83, no. 3 (2002): 551–60. http://dx.doi.org/10.1099/0022-1317-83-3-551.

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To identify new T-cell epitopes of classical swine fever virus (CSFV), 573 overlapping, synthetic pentadecapeptides spanning 82% of the CSFV (strain Glentorf) genome sequence were synthesized and screened. In proliferation assays, 26 peptides distributed throughout the CSFV viral protein sequences were able to induce specific T-cell responses in PBMCs from a CSFV-Glentorf-infected d/d haplotype pig. Of these 26 peptides, 18 were also recognized by PBMCs from a CSFV-Alfort/187-infected d/d haplotype pig. In further experiments, it could be shown that peptide 290 (KHKVRNEVMVHWFDD), which corresp

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29

Twarock, R. "A tiling approach to virus capsid assembly explaining a structural puzzle in virology." Journal of Theoretical Biology 226, no. 4 (2004): 477–82. http://dx.doi.org/10.1016/j.jtbi.2003.10.006.

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30

Singh, Bishal Kumar, Anna Koromyslova, and Grant S. Hansman. "Structural analysis of bovine norovirus protruding domain." Virology 487 (January 2016): 296–301. http://dx.doi.org/10.1016/j.virol.2015.10.022.

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31

Gauss-Müller, Verena, Friedrich Lottspeich, and Friedrich Deinhardt. "Characterization of hepatitis A virus structural proteins." Virology 155, no. 2 (1986): 732–36. http://dx.doi.org/10.1016/0042-6822(86)90234-5.

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32

Brown, Jay C., and William W. Newcomb. "Herpesvirus capsid assembly: insights from structural analysis." Current Opinion in Virology 1, no. 2 (2011): 142–49. http://dx.doi.org/10.1016/j.coviro.2011.06.003.

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33

Hu, Liya, Sue E. Crawford, Joseph M. Hyser, Mary K. Estes, and BV Venkataram Prasad. "Rotavirus non-structural proteins: structure and function." Current Opinion in Virology 2, no. 4 (2012): 380–88. http://dx.doi.org/10.1016/j.coviro.2012.06.003.

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34

Schlicksup, Christopher John, and Adam Zlotnick. "Viral structural proteins as targets for antivirals." Current Opinion in Virology 45 (December 2020): 43–50. http://dx.doi.org/10.1016/j.coviro.2020.07.001.

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35

Weber, Joseph, and Henri-A. Ménard. "Immunological cross-reactivity of adenovirus structural proteins." Journal of Virological Methods 13, no. 4 (1986): 363–67. http://dx.doi.org/10.1016/0166-0934(86)90061-3.

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36

Francis, M. I., J. A. Szychowski, and J. S. Semancik. "Structural sites specific to citrus viroid groups." Journal of General Virology 76, no. 5 (1995): 1081–89. http://dx.doi.org/10.1099/0022-1317-76-5-1081.

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37

Walker, P. J., and K. Kongsuwan. "Deduced structural model for animal rhabdovirus glycoproteins." Journal of General Virology 80, no. 5 (1999): 1211–20. http://dx.doi.org/10.1099/0022-1317-80-5-1211.

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38

BAN, NENAD, STEVEN B. LARSON, and ALEXANDER McPHERSON. "Structural Comparison of the Plant Satellite Viruses." Virology 214, no. 2 (1995): 571–83. http://dx.doi.org/10.1006/viro.1995.0068.

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39

Ströh, Luisa J., and Thomas Krey. "Structural insights into hepatitis C virus neutralization." Current Opinion in Virology 60 (June 2023): 101316. http://dx.doi.org/10.1016/j.coviro.2023.101316.

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40

Sevvana, Madhumati, Zhenyong Keck, Steven KH Foung, and Richard J. Kuhn. "Structural perspectives on HCV humoral immune evasion mechanisms." Current Opinion in Virology 49 (August 2021): 92–101. http://dx.doi.org/10.1016/j.coviro.2021.05.002.

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41

Rupp, Jonathan C., Kevin J. Sokoloski, Natasha N. Gebhart, and Richard W. Hardy. "Alphavirus RNA synthesis and non-structural protein functions." Journal of General Virology 96, no. 9 (2015): 2483–500. http://dx.doi.org/10.1099/jgv.0.000249.

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42

Sundqvist, A., M. Berg, P. Hernandez-Jauregui, T. Linne, and J. Moreno-Lopez. "The structural proteins of a porcine paramyxovirus (LPMV)." Journal of General Virology 71, no. 3 (1990): 609–13. http://dx.doi.org/10.1099/0022-1317-71-3-609.

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43

Strizki, J. M., and P. M. Repik. "Structural Protein Relationships Among Eastern Equine Encephalitis Viruses." Journal of General Virology 75, no. 11 (1994): 2897–909. http://dx.doi.org/10.1099/0022-1317-75-11-2897.

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44

Devant, Jessica M., and Grant S. Hansman. "Structural heterogeneity of a human norovirus vaccine candidate." Virology 553 (January 2021): 23–34. http://dx.doi.org/10.1016/j.virol.2020.10.005.

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45

Hayden, Melody, Mark B. Adams, and Sherwood Casjens. "Bacteriophage L: Chromosome physical map and structural proteins." Virology 147, no. 2 (1985): 431–40. http://dx.doi.org/10.1016/0042-6822(85)90145-x.

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46

Baquero, Eduard, Aurélie A. Albertini, Patrice Vachette, Jean Lepault, Stéphane Bressanelli, and Yves Gaudin. "Intermediate conformations during viral fusion glycoprotein structural transition." Current Opinion in Virology 3, no. 2 (2013): 143–50. http://dx.doi.org/10.1016/j.coviro.2013.03.006.

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47

Lozano, Gloria, and Encarnación Martínez-Salas. "Structural insights into viral IRES-dependent translation mechanisms." Current Opinion in Virology 12 (June 2015): 113–20. http://dx.doi.org/10.1016/j.coviro.2015.04.008.

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48

Charleston, Bryan, and Simon P. Graham. "Recent advances in veterinary applications of structural vaccinology." Current Opinion in Virology 29 (April 2018): 33–38. http://dx.doi.org/10.1016/j.coviro.2018.02.006.

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49

Lin, William, Jeannie L. Shurgot, and Harumi Kasamatsu. "The synthesis and transport of SV40 structural proteins." Virology 154, no. 1 (1986): 108–20. http://dx.doi.org/10.1016/0042-6822(86)90434-4.

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50

Baron, Michael D., and Kerstin Forsell. "Oligomerisation of the structural proteins of Rubella virus." Virology 185, no. 2 (1991): 811–19. http://dx.doi.org/10.1016/0042-6822(91)90552-m.

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