Literatura académica sobre el tema "T cells Receptors"

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Artículos de revistas sobre el tema "T cells Receptors"

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Y, Elshimali. "Chimeric Antigen Receptor T-Cell Therapy (Car T-Cells) in Solid Tumors, Resistance and Success." Bioequivalence & Bioavailability International Journal 6, no. 1 (2022): 1–6. http://dx.doi.org/10.23880/beba-16000163.

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CARs are chimeric synthetic antigen receptors that can be introduced into an immune cell to retarget its cytotoxicity toward a specific tumor antigen. CAR T-cells immunotherapy demonstrated significant success in the management of hematologic malignancies. Nevertheless, limited studies are present regarding its efficacy in solid and refractory tumors. It is well known that the major concerns regarding this technique include the risk of relapse and the resistance of tumor cells, in addition to high expenses and limited affordability. Several factors play a crucial role in improving the efficacy
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Meiliana, Anna, Nurrani Mustika Dewi, and Andi Wijaya. "CAR T Cells: Precision Cancer Immunotherapy." Indonesian Biomedical Journal 10, no. 3 (December 28, 2018): 203–16. http://dx.doi.org/10.18585/inabj.v10i3.635.

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BACKGROUND: Current cancer drugs and treatments are aiming at eradicating tumor cells, but often are more toxic then effective, killing also the normal cells and not selectively the tumor cells. There is good personalized cancer therapy that involves administration to the cancer-bearing host of immune cells with direct anticancer activity, which called adoptive cell therapy (ACT). A review of the unique biology of T cell therapy and of recent clinical experience compels a reassessment of target antigens that traditionally have been viewed from the perspective of weaker immunotherapeutic modali
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Steverding, Dietmar. "Cycle Numbers of Cell Surface Recycling Receptors." Receptors 2, no. 2 (June 6, 2023): 160–65. http://dx.doi.org/10.3390/receptors2020010.

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The cycle number (nc) of a recycling receptor is defined as the average number of round trips (cell surface–endosome–cell surface) the receptor can make before it is degraded. This characteristic parameter of recycling receptors can be easily determined from the receptor’s half-life (t½, the time in which 50% of the receptor is degraded) and cycling time (Tc, the time a receptor needs to complete a round trip). Relationship analyses revealed that nc increases linearly with increasing t½ and decreases exponentially with increasing Tc. For commonly observed t½ and Tc values, it was calculated th
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Coico, R. F., B. Xue, D. Wallace, B. Pernis, G. W. Siskind, and G. J. Thorbecke. "T cells with receptors for IgD." Nature 316, no. 6030 (August 1985): 744–46. http://dx.doi.org/10.1038/316744a0.

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Klein, Thomas W., Cathy Newton, Kellie Larsen, Joe Chou, Izabella Perkins, Lily Lu, Liang Nong, and Herman Friedman. "Cannabinoid receptors and T helper cells." Journal of Neuroimmunology 147, no. 1-2 (February 2004): 91–94. http://dx.doi.org/10.1016/j.jneuroim.2003.10.019.

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Rossig, Claudia, Catherine M. Bollard, Jed G. Nuchtern, Cliona M. Rooney, and Malcolm K. Brenner. "Epstein-Barr virus–specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy." Blood 99, no. 6 (March 15, 2002): 2009–16. http://dx.doi.org/10.1182/blood.v99.6.2009.

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Abstract Primary T cells expressing chimeric receptors specific for tumor or viral antigens have considerable therapeutic potential. Unfortunately, their clinical value is limited by their rapid loss of function and failure to expand in vivo, presumably due to the lack of costimulator molecules on tumor cells and the inherent limitations of signaling exclusively through the chimeric receptor. Epstein-Barr virus (EBV) infection of B lymphocytes is near universal in humans and stimulates high levels of EBV-specific helper and cytotoxic T cells, which persist indefinitely. Our clinical studies ha
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Sato, Noriko, Richard N. Bamford, Bonita R. Bryant, Yutaka Tagaya, and Thomas A. Waldmann. "Accessory cells precondition naive T cells and regulatory T cells for cytokine-mediated proliferation." Journal of Immunology 210, no. 1_Supplement (May 1, 2023): 164.02. http://dx.doi.org/10.4049/jimmunol.210.supp.164.02.

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Abstract Naïve T cells and regulatory T cells, when purified, do not proliferate to the common cytokine receptor γ-chain family cytokines interleukin (IL)-2, IL-7 or IL-15, despite their expression of cognate cytokine receptors. Cell-to-cell contact with dendritic cells (DCs) enabled proliferation of the T cell to these cytokines, independent of antigen recognition or T cell receptor stimulation. This effect lasted after separation of T cells from DCs, enabling enhanced proliferation of the T cells in mice depleted of DCs. We propose calling this a “preconditioning effect”. Interestingly, IL-2
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Suzuki, T., and M. D. Cooper. "Comparison of the expression of IL 2 receptors by human T and B cells: induction by the polyclonal mitogens, phorbol myristate acetate, and anti-mu antibody." Journal of Immunology 134, no. 5 (May 1, 1985): 3111–19. http://dx.doi.org/10.4049/jimmunol.134.5.3111.

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Abstract It is well established that IL 2 plays an important role in the proliferative response of T cells. Activated B cells were also recently found to express IL 2 receptors. The present studies were designed to compare qualitative, quantitative, and functional aspects of IL 2 receptor expression by activated T and B cells. Phorbol myristate acetate (PMA)-activated human T and small resting B cells and enhanced the expression of HLA-DR, HLA-DC/DS, and transferrin receptors while reducing Leu-4 antigen expression by T cells and IgM and IgD expression on B cells. PMA induced both T and B cell
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Scheurich, P., B. Thoma, U. Ucer, and K. Pfizenmaier. "Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses." Journal of Immunology 138, no. 6 (March 15, 1987): 1786–90. http://dx.doi.org/10.4049/jimmunol.138.6.1786.

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Abstract The expression of specific tumor necrosis factor (TNF) membrane receptors and biological effects of recombinant TNF (rTNF)-alpha on normal human T lymphocytes were studied. Although resting T cells lacked specific binding capacity for rTNF-alpha, high affinity (Kd 70 pM) TNF receptors were de novo induced upon primary activation of T cells. Comparison of TNF receptor expression with that of high affinity interleukin 2 (IL-2) and interferon-gamma (IFN-gamma) receptors, respectively, revealed similarities to IL 2-receptor expression with respect to kinetics of induction. However, maximu
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Aune, T. M., K. M. McGrath, T. Sarr, M. P. Bombara, and K. A. Kelley. "Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine." Journal of Immunology 151, no. 3 (August 1, 1993): 1175–83. http://dx.doi.org/10.4049/jimmunol.151.3.1175.

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Abstract The neurotransmitter, serotonin (5-hydroxytryptamine, 5HT), has been shown to affect function of cells of the immune system. More recently, specific 5HT receptors have been identified and partially characterized on Jurkat cells. Results presented here characterize the receptor on Jurkat cells as the 5HT1a receptor subtype and show that mitogen-activated but not resting human T cells also express the 5HT1a receptor subtype. Analysis of mRNA in Jurkat cells and activated and resting T cells by PCR or by Northern analysis revealed the presence of 5HT1a receptor. Pharmacologic analysis of
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Tesis sobre el tema "T cells Receptors"

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Soper, David Michael. "Interleukin-2 receptor and T cell receptor signaling in regulatory T cells /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8344.

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Carson, Bryan David. "Impaired T cell receptor signaling in regulatory T cells /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8337.

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Ebert, Lisa Michelle. "The regulation of chemokine receptor expression upon T lymphocyte activation." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phe165.pdf.

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Parra, Eduardo. "Molecular basis for costimulation of human T lymphocytes." Lund : Lund University, 1998. http://books.google.com/books?id=SgFrAAAAMAAJ.

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Carlsson, Fredrik. "Antibody Feedback Regulation and T Cells." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7631.

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Tanaka, Yujiro. "Selection of T cells in the thymus." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294749.

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Chan, Ping-lung, and 陳秉隆. "Roles of TLR5 and ICOS on the human allogenic CD40-activated B cell-induced CD4hiCD25+ regulatory T cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47149735.

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Neeraj. "Studies on equine helper T cells and Fcγ receptors". Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627077.

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Crocker, Glenn. "A study of surface receptors on rat T lymphocytes." Thesis, University of Oxford, 1991. http://ora.ox.ac.uk/objects/uuid:5c74a70b-1f5e-4c78-904f-7c4ff1b543a8.

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A double immunolabelling technique was developed to study microscopically the interactions between CD4, CD45 and the T cell receptor on the surface of rat T cells induced by the phenomenon of co-capping. It was found that both CD4 and CD45 passively co-cap with the actively capped T cell receptor, that the T cell receptor and CD45 passively co-cap with CD4, but that neither CD4 nor the T cell receptor co-cap with CD45. Co-crosslinking and active capping of CD45 with either the T cell receptor or CD4 prevented CD4 or the T cell receptor respectively, from passively co-capping. These experiments
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Jiang, Ning. "Kinetic analysis of Fcγ receptor and T cell receptor interacting with respective ligands". Diss., Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/26716.

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Low affinity Fcg receptor III (FcgRIII, CD16) triggers a variety of cellular events upon binding to the Fc portion of IgG. A real-time flow cytometry method was developed to measure the affinity and kinetics of such low affinity receptor/ligand interactions, which was shown as an easily operated yet powerful tool. Results revealed an unusual temperature dependence of reverse rate of CD16aTM dissociating from IgG. Except for a few studies using mammalian cell CD16s, most kinetics analyses use purified aglycosylated extracellular portion of the molecules, making it impossible to assess the impor
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Libros sobre el tema "T cells Receptors"

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1945-, Mak Tak W., ed. The T-cell receptors. New York: Plenum Press, 1988.

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Brondz, Boris Davydovich. T lymphocytes and their receptors in immunologic recognition. London, Eng: Harwood Academic Publishers, 1988.

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M, Davis Mark, Kappler John, University of California, Los Angeles., and UCLA Symposium on the T Cell Receptor (1987 : Keystone, Colo.), eds. The T-cell receptor: Proceedings of a Smith Kline & French-UCLA symposium, held in Keystone, Colorado, April 26-May 1, 1987. New York: A.R. Liss, 1988.

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R, Oksenberg Jorge, ed. The antigen T cell receptor: Selected protocols and applications. New York: R.G. Landes, 1997.

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1932-, Haber Edgar, ed. Antigen binding molecules: Antibodies and T-cell receptors. San Diego: Academic Press, 1996.

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Dimitrov, Dimiter S. HIV and membrane receptors. New York: Chapman & Hall, 1997.

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M, Davis Mark, and Buxbaum Joel, eds. T-cell receptor use in human autoimmune diseases. New York, N.Y: New York Academy of Sciences, 1995.

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Van den Elsen, Peter J., 1951-. The human T-cell receptor repertoire and transplantation. New York: Springer Verlag, 1995.

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Marc, Feldmann, Lamb Jonathan R, and Woody James N, eds. Human T cell clones: A new approach to immune regulation. Clifton, N.J: Humana Press, 1985.

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Jean-François, Bach, ed. T-cell-directed immunointervention. Oxford [England]: Blackwell Scientific Publications, 1993.

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Capítulos de libros sobre el tema "T cells Receptors"

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Sandor, M., and R. G. Lynch. "FcγR on T cells." In The Immunoglobulin Receptors and their Physiological and Pathological Roles in Immunity, 169–83. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5018-7_16.

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Moretta, A., S. Sivori, M. Ponte, M. C. Mingari, and L. Moretta. "Stimulatory Receptors in NK and T Cells." In Specificity, Function, and Development of NK Cells, 15–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-46859-9_2.

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Mage, Rose G., and Claire Rogel-Gaillard. "Immunogenetics in the rabbit." In The genetics and genomics of the rabbit, 66–83. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781780643342.0005.

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Abstract This chapter on immunogenetics in the rabbit focused on some genes with genetic and genomic sequence information including those encoding: soluble circulating immunoglobulin molecules (Igs) and their surface-bound forms on B lymphocytes (BCRs); T-cell receptors on T lymphocyte surfaces, (TCRs); the rabbit Leukocyte Antigen (RLA) complex (proteins on cells that function to present antigen fragments to TCRs); and some cytokine genes that encode key regulators of T- and B-cell responses.
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Anfossi, Nicolas, Véronique Pascal, Sophie Ugolini, and Eric Vivier. "Characterization of Tm1 cells, a NKR+ subset of memory-phenotype CD8+ T cells." In Activating and Inhibitory Immunoglobulin-like Receptors, 225–34. Tokyo: Springer Japan, 2001. http://dx.doi.org/10.1007/978-4-431-53940-7_28.

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Williams, J. M., and T. B. Strom. "De Novo Expression of Receptors on T Cells." In Handbook of Experimental Pharmacology, 37–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73217-1_3.

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Rapoport, Aaron P., and Jean A. Yared. "T Cell Receptors-Gene-Modified T Cells for Cancer: Methods, Data, and Challenges." In Advances and Controversies in Hematopoietic Transplantation and Cell Therapy, 109–33. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-54368-0_7.

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Modlin, Robert L., Julie Lewis, Koichi Uyemura, and Robert E. Tigelaar. "T Lymphocytes Bearing Gamma-Delta Antigen Receptors in Skin." In Heat-Shock Proteins and Gamma-Delta T Cells, 61–74. Basel: KARGER, 1992. http://dx.doi.org/10.1159/000319103.

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Hellmeier, Joschka, René Platzer, Johannes B. Huppa, and Eva Sevcsik. "A DNA Origami-Based Biointerface to Interrogate the Spatial Requirements for Sensitized T-Cell Antigen Recognition." In The Immune Synapse, 277–302. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3135-5_18.

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AbstractWhen T cells scan the surface of antigen-presenting cells (APCs), they can detect the presence of just a few antigenic peptide/MHC complexes (pMHCs), in some cases even a single agonist pMHC. These are typically vastly outnumbered by structurally similar yet non-stimulatory endogenous pMHCs. How T cells achieve this enormous sensitivity and selectivity is still not clear, in particular in view of the rather moderate (1–100 μM) affinity that T-cell receptors (TCRs) typically exert for antigenic pMHCs. Experimental approaches that enable the control and quantification of physical input parameters within the context of the immunological synapse to precisely interrogate the molecular consequences of TCR-engagement, appear highly advantageous when searching for better answers.We here describe the implementation of a biointerface that allows to experimentally define molecular distances between T-cell ligands as a means to correlate them with molecular dynamics of antigen engagement, downstream signaling, and the overall T-cell response. The basis of this biointerface is DNA origami nanostructures, which are (i) rigid and highly versatile platforms that can (ii) be embedded as laterally mobile entities within supported lipid bilayers and functionalized (iii) in a site-specific and orthogonal manner with (iv) one or more proteins of choice.
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Ferrick, David A., and Lorraine Gemmell-Hori. "Potential Developmental Role for Self-Reactive T Cells Bearing Gamma-Delta T Cell Receptors Specific for Heat-Shock Proteins." In Heat-Shock Proteins and Gamma-Delta T Cells, 17–31. Basel: KARGER, 1992. http://dx.doi.org/10.1159/000319100.

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Marinez-A., C., J. M. Alonso, Alicia Barcena, P. Aparicio та Maria L. Toribio. "From the Developmental Expression of γδ T Cell Receptors to the Implications in the Acquisition of Tolerance". У Function and Specificity of γ/δ T Cells, 17–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_3.

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Actas de conferencias sobre el tema "T cells Receptors"

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Chang, ZeNan L., Pamela A. Silver, and Yvonne Y. Chen. "Abstract B022: Functional bifurcation in T cells expressing chimeric antigen receptors." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-b022.

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Strijker, JGM, E. Drent, JJF van der Hoek, R. Pscheid, B. Koopmans, K. Ober, SR van Hooff та ін. "P06.01 αβ-T cells engineered to express γδ-T cell receptors can kill neuroblastoma organoids independent of MHC-I expression". У iTOC8 – the 8th Leading International Cancer Immunotherapy Conference in Europe, 8–9 October 2021, Virtual Conference. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/jitc-2021-itoc8.35.

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Gavin, Marc A., Alexander Gragerov, Erik Espling, Alex Rohde, Tim Sexton, Christiana Doulami, and George Gaitanaris. "Abstract B45: Phosphatidylserine suppresses T cells through GPR174, and co-inhibition of adenosine receptors and GPR174 synergistically enhances T cell responses." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-b45.

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Lu, Binfeng, Min Yang, Wenwen Du, Wensi Zhai, Runzi Sun, Cuihua Yue, and Jingting Jiang. "Abstract B06: Immune inhibitory receptors restrain hyperactivated effector T cells in the tumor microenvironment." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 27-30, 2018; Miami Beach, FL. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm18-b06.

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Smith, Duane, Payal Watchmaker, Guido Stadler, Natalie Marks, Yelena Bronevetsky, Keviin Chapman, and Hideho Okada. "Abstract 5773: Sequencing and cloning IDH1 R132H-targeted monoclonal T cell receptors from CD4+T cells facilitated by opto-electric-positioning technology." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-5773.

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Nadigel, J., D. Prefontaine, J. Bourbeau, F. Maltais, D. Eidelman, and Q. Hamid. "The Expression of Toll-Like Receptors in CD8+T Cells in Chronic Obstructive Pulmonary Disease." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1005.

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Yu, Yingyan, Eva Brudy, Rabea Imker, Cornelia Dalibor, Oliver Eickelberg, and Susanne Krauss-Etschmann. "Upregulation Of Pulmonary Chemokine Receptor 2 (CCR2) Positive T Cells And Their Chemokine Receptors Profile In Bleomycin-Induced Lung Fibrosis." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5397.

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Chang, Lung-Ji, Yuchen Liu, and Jan S. Moreb. "Abstract 2796: Engineering multiple chimeric antigen receptors in T cells for the treatment of multiple myeloma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2796.

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Bergamini, Alice, Elena Tassi, Miriam Sant’Angelo, Chiara Balestrieri, Emanuela Brunetto, Miriam Redegalli, Alessia Potenza, et al. "2022-RA-1651-ESGO Epithelial Ovarian Cancer is infiltrated by activated effector T cells coexpressing multiple inhibitory receptors and by myeloid cells expressing inhibitory receptor ligands." In ESGO 2022 Congress. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-esgo.901.

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Nishiyama, Shuhei, Amy Wright, Itay Lotan, Friedemann Paul, and Michael Levy. "Upregulated complement receptors correlate with Fc gamma receptor 3A-positive natural killer cells (NK) and natural killer-T cells (NKT) in neuromyelitis optica spectrum disorder. (S50.003)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203565.

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Informes sobre el tema "T cells Receptors"

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Tzfira, Tzvi, Michael Elbaum, and Sharon Wolf. DNA transfer by Agrobacterium: a cooperative interaction of ssDNA, virulence proteins, and plant host factors. United States Department of Agriculture, December 2005. http://dx.doi.org/10.32747/2005.7695881.bard.

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Agrobacteriumtumefaciensmediates genetic transformation of plants. The possibility of exchanging the natural genes for other DNA has led to Agrobacterium’s emergence as the primary vector for genetic modification of plants. The similarity among eukaryotic mechanisms of nuclear import also suggests use of its active elements as media for non-viral genetic therapy in animals. These considerations motivate the present study of the process that carries DNA of bacterial origin into the host nucleus. The infective pathway of Agrobacterium involves excision of a single-stranded DNA molecule (T-strand
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Altstein, Miriam, and Ronald J. Nachman. Rational Design of Insect Control Agent Prototypes Based on Pyrokinin/PBAN Neuropeptide Antagonists. United States Department of Agriculture, August 2013. http://dx.doi.org/10.32747/2013.7593398.bard.

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The general objective of this study was to develop rationally designed mimetic antagonists (and agonists) of the PK/PBAN Np class with enhanced bio-stability and bioavailability as prototypes for effective and environmentally friendly pest insect management agents. The PK/PBAN family is a multifunctional group of Nps that mediates key functions in insects (sex pheromone biosynthesis, cuticular melanization, myotropic activity, diapause and pupal development) and is, therefore, of high scientific and applied interest. The objectives of the current study were: (i) to identify an antagonist bioph
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Baszler, Timothy, Igor Savitsky, Christopher Davies, Lauren Staska, and Varda Shkap. Identification of bovine Neospora caninum cytotoxic T-lymphocyte epitopes for development of peptide-based vaccine. United States Department of Agriculture, March 2006. http://dx.doi.org/10.32747/2006.7695592.bard.

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The goal of the one-year feasibility study was to identify specific cytotoxic T-lymphocyte (CTL) epitopes to Neosporacaninum in the natural bovine host in order to make progress toward developing an effective peptide-based vaccine against bovine neosporosis. We tested the hypothesis that: N. caninum SRS2 peptides contain immunogenicCTLepitope clusters cross-presented by multiple bovine MHC-I and MHC-IIhaplotypes. The specific objectives were: (1) Map bovine CTLepitopes of N. caninum NcSRS-2 and identify consensus MHC-I and class-II binding motifs; and (2) Determine if subunit immunization with
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Weinberg, Andrew D. Tumor Specific CD4+ T-Cell Costimulation Through a Novel Receptor/Ligand Interaction. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada374764.

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5

Wiley, Don C., and David N. Garboczi. Structural Analysis of the Human T-Cell Receptor/HLA-A2/Peptide Complex. Fort Belvoir, VA: Defense Technical Information Center, August 1997. http://dx.doi.org/10.21236/ada342257.

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Weinberg, Andrew D. Tumor Specific CD4+ T-Cell Costimulation Through a Novel Receptor Ligand Interaction. Fort Belvoir, VA: Defense Technical Information Center, August 1998. http://dx.doi.org/10.21236/ada359629.

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Gray, Andrew. Enhancing the Efficacy of Prostate Cancer Immunotherapy by Manipulating T-Cell Receptor Signaling in Order to Alter Peripheral Regulatory T-Cell Activity. Fort Belvoir, VA: Defense Technical Information Center, July 2009. http://dx.doi.org/10.21236/ada511997.

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Gray, Andrew. Enhancing the Efficacy of Prostate Cancer Immunotherapy by Manipulating T-Cell Receptor Signaling in Order to Alter Peripheral Regulatory T-Cell Activity. Fort Belvoir, VA: Defense Technical Information Center, July 2011. http://dx.doi.org/10.21236/ada553485.

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9

Fluhr, Robert, and Maor Bar-Peled. Novel Lectin Controls Wound-responses in Arabidopsis. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7697123.bard.

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Innate immune responses in animals and plants involve receptors that recognize microbe-associated molecules. In plants, one set of this defense system is characterized by large families of TIR–nucleotide binding site–leucine-rich repeat (TIR-NBS-LRR) resistance genes. The direct interaction between plant proteins harboring the TIR domain with proteins that transmit and facilitate a signaling pathway has yet to be shown. The Arabidopsis genome encodes TIR-domain containing genes that lack NBS and LRR whose functions are unknown. Here we investigated the functional role of such protein, TLW1 (TI
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Zhao, Kangjia, Jiwen Sun, Nanping Shen, Mengxue He, Haishan Ruan, Geng Lin, Jiali Ma, and Yanhua Xu. Treatment-Related Adverse Events of Chimeric Antigen receptor T-Cell (CAR-T) Cell Therapy in B-cell hematological malignancies in the Pediatric and Young Adult Population: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2022. http://dx.doi.org/10.37766/inplasy2022.7.0034.

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