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1

Hasson, Kahtan J. "Comparative study for the dissolution of Isosorbide dinitrate tablets in commercial products." Al Mustansiriyah Journal of Pharmaceutical Sciences 9, no. 1 (2011): 7–12. http://dx.doi.org/10.32947/ajps.v9i1.267.

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Isosorbide dinitrate is prepared as a solid dosage forms, and found in the market as a sublingual tablet or conventional tablet of 10mg for oral administration which is subjected to the dissolution study.In this present work, different commercial products of Isosorbide dinitrate tablets were subjected to dissolution test according to USP method which includes an HPLC determination. The dissolution profiles of three commercial products of isosorbide dintrate tablets and preformulated product were evaluated by comparing with that of reference standard (European product. Actavis Co.) .Due to low
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2

Bracken, Louise, Emma McDonough, Joanne Shakeshaft, et al. "SP8 Creating acceptable tablets 3D (CAT 3D): a feasibility study to evaluate the mouthfeel of 3D printed tablets in children and young people." Archives of Disease in Childhood 105, no. 9 (2020): e5.1-e5. http://dx.doi.org/10.1136/archdischild-2020-nppg.8.

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AimTo evaluate the feasibility of a study investigating the mouthfeel of different sized 3D printed placebo solid dosage forms (SDFs) in children and young people (CYP) aged 4–12 years.MethodAll participants in the CAT 3D Study had previously participated in the Creating Acceptable Tablets (CAT) Study, a feasibility study which assessed the swallowability and acceptability of different sized placebo tablets, and therefore only attempted to swallow one 3D printed tablet. If the participant had successfully swallowed all three tablet sizes in the CAT Study (6 mm, 8 mm, 10 mm) they were then rand
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3

Nolly, Robert J., Patrick Rodrigues, and Laura Thoma. "Weight Variability of Scored and Unscored Psychotropic Drug Tablets Split by a Uniquely Designed Tablet Splitting Device." Hospital Pharmacy 40, no. 4 (2005): 321–25. http://dx.doi.org/10.1177/001857870504000406.

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Tablets of three psychotropic drugs were split using a uniquely designed tablet splitting device, the Tru-Cut Multi-Tablet Cutter, and evaluated for weight variation utilizing criteria based on the United States Pharmacopeia (USP) <27> Uniformity of Dosage Units Content Uniformity Criteria. Whole tablets of Risperdal 2 mg and 4 mg, Paxil 20 mg and 40 mg, and Zoloft 100 mg were split by a device that positioned tablets in tablet specific disposable trays for splitting. Each half tablet weight was recorded utilizing a digital electronic balance. Weight variability was determined by compari
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4

Jacques, Emmanuel Reginald, and Paschalis Alexandridis. "Tablet Scoring: Current Practice, Fundamentals, and Knowledge Gaps." Applied Sciences 9, no. 15 (2019): 3066. http://dx.doi.org/10.3390/app9153066.

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Oral solid dosage formulations and/or tablets have remained the preferred route of administration by both patients and health care practitioners. Oral tablets are easy to administer, they are non-invasive and cause less risk adversity. Because of the lack of commercially available tablet dose options, tablets are being split or partitioned by users. Tablet scoring refers to the breakage of a tablet to attain a desired efficacy dose and is an emerging concept in the pharmaceutical industry. The primary reason for the tablet scoring practice is to adjust the dose: dose tapering or dose titrating
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5

Siti Mursidatur Rohmah, Dewi Rashati,. "UJI FISIK FORMULASI TABLET FLOATING TEOFILIN DENGAN MATRIK HPMC." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 1, no. 1 (2021): 13–20. http://dx.doi.org/10.53864/jifakfar.v1i1.6.

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The purpose of this study was to determine the physical properties of theophylline floating tablet formulation with HPMC as matrix. Floating tablets of theophylline is manufactured by direct compression. Composition per tablet formulation consisting of theophylline 270 mg, HPMC, avicel, magnesium stearate, and sodium bicarbonate. The results of data showed average of tablet weight uniformity 501mg, tablet hardness 6,99 kg, tablet friability 0,593%, disintegration time of tablets 738 seconds, floating lag time (FLT) 584,3 seconds and floating duration time (FDT) more than 8 hours. Floating tabl
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6

Nurhayati, Lis, Emah Marhamah, Asiq'atul Fuady, and Natasya Berliana Putri Olivia. "PENGETAHUAN ANEMIA DAN TABLET FE TERHADAP KEPATUHAN MINUM TABLET FE." Jurnal Keperawatan Karya Bhakti 10, no. 1 (2024): 45–53. https://doi.org/10.56186/jkkb.136.

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Abstrak Latar Belakang: Anemia merupakan kondisi dimana jumlah konsentrasi darah yang mengangkut oksigen dan sel darah merah tidak sesuai fisiologi tubuh. Anemia lebih banyak terjadi pada remaja putri karena proses menstruasi sehingga akan mengalami kehilangan zat besi sekitar 30 mg. Anemia pada remaja berdampak buruk terhadap penurunan imunitas, konsentrasi, prestasi belajar, kebugaran remaja. Remaja putri merupakan calon ibu yang nantinya akan mengalami proses kehamilan dan persalinan. Kondisi kekurangan zat besi dapat memperbesar risiko kematian maternal, bayi lahir prematur dan BBLR. Anemi
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7

Luke, Stefani, Martha Ervina, and Lannie Hadisoewignyo. "Optimization of Coating Formula of White Pomegranate Peel Extract (Punica granatum L.) Film Coated Tablet Using Kollicoat Protect." Indonesian Journal of Pharmaceutical Research 1, no. 1 (2021): 19–27. http://dx.doi.org/10.31869/ijpr.v1i1.1993.

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White pomegranate peel has many kinds uses, one of them as antimalaria. The unpleasant appearance and bitter taste of white pomegranate peel tablet can be covered by film coated using Kollicoat Protect. This research aimed to determine the effect of concentration and type of solvent used as a coating on the physical properties of the coated tablets and determine the optimum formula. Tablets were made using direct compression method and then coated using Kollicoat Protect. The optimization of coating formula was performed using a factorial design with design expert software ver 10.0. Responses
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8

Rosaini, Henni, Rina Wahyuni, Addina Zafrul, and Ela Indah Sari. "FORMULATION AND CHARACTERIZATION OF TABLETS FROM SIMPLICIA AND EXTRACT OF SUNGKAI’S (Peronema canescens Jack) LEAF." International Journal of Pharmaceutical Sciences and Medicine 8, no. 10 (2023): 65–75. http://dx.doi.org/10.47760/ijpsm.2023.v08i10.006.

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Tablets are solid preparations containing medicinal ingredients with or without excipients, usually consisting of one or more active substances. Preparations in tablet form have the best mechanical, chemical, and microbiological stability compared to liquid dosage forms, so they are more resistant to physical damage. This study aims to formulation and characterization of tablet from simplicia and dried extract of sungkai’s (Peronema canescens Jack) leaf by wet granulation which consisted of three formulas, namely F1 without active substances, F2 active substances from sungkai’s leaf simplicia,
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9

Sinaga, Alex Handani, and Novicha Aulya Fendri. "Addition Of Various Concentrations Of Gadung Tuber Starch Which Is Determined As A Binder To The Physical Properties Of Mefanamic Acid Tablets By Wet Granulation." Jurnal Kesehatan, Rekam Medis dan Farmasi (JUK-Medifa) 2, no. 01 (2023): 25–31. https://doi.org/10.58471/juk-medifa.v2i01.234.

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n previous studies, the polysaccharide extract of gadung tuber has a hypoglycemic effect, wherein the plant contains a high glycemic index indicating that carbohydrates undergo rapid digestion and are absorbed in large quantities so that blood glucose levels suddenly experience a rapid rise in insulin which can lower cholesterol values. (Sumunar et al., 2015) This research method is an experiment in which this research was carried out, by making starch from gadung starch and making tablets by wet granulation. Based on the results of the research that has been done, it can be concluded that the
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10

Sari, Rodiah Nurbaya, Hari Eko Irianto, and Ema Hastarini. "Production of Unsaturated Fatty Acids Concentrate Tablets from Sardinella sp. Oil." E3S Web of Conferences 147 (2020): 03008. http://dx.doi.org/10.1051/e3sconf/202014703008.

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Tablets are medicinal ingredients in solid dosage forms which are usually prepared with suitable pharmaceutical ingredients. In this study, unsaturated fatty acids concentrate from Sardinella sp. oil was used as raw material and then it was microencapsulated. The microcapsule was formulated into a tablet with proportion of 250 mg concentrated unsaturated fatty acids for each 450 mg tablet. Tablet granules were analyzed for compressibility, flow rate, and fixed angle. While, the tablets were determined for weight uniformity, released time, hardness, and tablet size uniformity. The results showe
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11

Karandule, Akshay, Komal Madake, Rajeshwari Khairnar, and Rupali Tasgaonkar. "Tablet Binders." International Journal for Research in Applied Science and Engineering Technology 11, no. 1 (2023): 675–81. http://dx.doi.org/10.22214/ijraset.2023.48663.

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Abstract: The tablet formulation contains binders that increase the interparticulate bond power inside the tablet. Research and progress of novel accessories remains a priority for potential use as a binder in formulations tablet. Tablet binder or binding agent are the substances that are added either dry or in liquid form during wet granulation to form granules or to promote cohesive compacts for directly compressed tablets. E.g., starch, pregelatinized starch, PEG, sorbitol, and HPMC, etc. Tablet Binder and disintegrants have the opposite used in an oral solid formulation. Binder delay table
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12

Windriyati, Yulias Ninik, Melany Dyah Sulistyo Rini, Dwi Aji Anggara, and Nina Fitriani. "Liquisolid tablets formulation of atorvastatin calcium using propylene glycol as solvent and some carrier materials Formulasi tablet likuisolid kalsium atorvastatin dengan pelarut propilenglikol dan beberapa bahan pembawa." Jurnal Ilmiah Farmasi 19, no. 2 (2023): 169–81. http://dx.doi.org/10.20885/jif.vol19.iss2.art15.

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Abstract Background: Marketed tablets of drugs must fulfill the required standards of dissolution to guarantee the equivalent to reference. Atorvastatin calcium needs to be enhanced dissolution since this compound included BCS Class II drugs with low solubility and high permeability. This meaning that the dissolution affects the bioavailability of drugs.Objective: This research aimed to develop a formulation of a liquisolid tablet using propylene glycol as a solvent and some carrier materials in various compositions to increase the dissolution of atorvastatin calcium.Method: Different formulat
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13

Suprapto, Muhamad Eza, Santi Rosniawaty, and Mira Ariyanti. "Pengaruh Pupuk Kompos Kulit Buah Kakao Dan Pupuk Tablet Terhadap Produksi Kakao (Theobroma cacao L.)." Paspalum: Jurnal Ilmiah Pertanian 6, no. 1 (2018): 41. http://dx.doi.org/10.35138/paspalum.v6i1.76.

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Cocoa is one of the estate crop whose role is quite important for the national economy, particularly as a provider of employment, income and foreign exchange. The high export opportunities of cocoa beans has not been followed by the production of cocoa beans in Indonesian. The production of dried cacao beans in Indonesia is still low. The low productivity of seeds generally caused by Cherelle wilt of cacao. Wilting occurs due to inability of the cherelle to compete with the other cherelle in absorbing nutrients. Fertilization is an effort to maintain and fulfill the nutrients in the plants. Th
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14

Wang, Yifei, Zhisheng Wu, Zhaoyi Wang, Manfei Xu, Xinyuan Shi, and Yanjiang Qiao. "Rapid analysis of spatial distribution of PVPP and hardness of Yinhuang dispersible tablets by NIR-CI." Journal of Innovative Optical Health Sciences 09, no. 02 (2016): 1550016. http://dx.doi.org/10.1142/s1793545815500169.

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The present study aimed at investigating the relationship between tablet hardness and homogeneity of different Yinhuang dispersible tablets by near-infrared chemical imaging (NIR-CI) technology. The regularity of best hardness was founded between tablet hardness and the spatial distribution uniformity of Yinhuang dispersible tablets. The ingredients homogeneity of Yinhuang dispersible tablets could be spatially determined using basic analysis of correlation between analysis (BACRA) method and binary image. Then different hardnesses of Yinhuang dispersible tablets were measured. Finally, the re
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15

Kailash Sahu, Vimlendu Kumar, Pooja Lodhi, and Bhaskar Kumar Gupta. "Different types of pharmaceutical tablets used for treatment of diseases." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 001–11. http://dx.doi.org/10.30574/gscbps.2022.21.2.0398.

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In modern age of revolution and development in drug delivery for better clinical effects conventional dosages form have still a strong grip and most popular in all kinds of medicinal preparation intended for oral use. To satisfy the need of growing market tablets dosages form have incorporated modernization in producing and some advanced tablet types. Modified release tablet formulations including, layered tablets such as In +--lay tablet, Bi-layered tablet, Medicated chewing gum, Tablet tarts, Pastilles, Lollipop, Tablet inserts, Clinicaps, Caplets, Child ecstasy tablet and Tablet in tablet a
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16

Kailash, Sahu, Kumar Vimlendu, Lodhi Pooja, and Kumar Gupta Bhaskar. "Different types of pharmaceutical tablets used for treatment of diseases." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 001–11. https://doi.org/10.5281/zenodo.7649131.

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In modern age of revolution and development in drug delivery for better clinical effects conventional dosages form have still a strong grip and most popular in all kinds of medicinal preparation intended for oral use. To satisfy the need of growing market tablets dosages form have incorporated modernization in producing and some advanced tablet types. Modified release tablet formulations including, layered tablets such as In +--lay tablet, Bi-layered tablet, Medicated chewing gum, Tablet tarts, Pastilles, Lollipop, Tablet inserts, Clinicaps, Caplets, Child ecstasy tablet and Tablet in tablet a
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17

Asmirati, Ira Mayasari, and Andi Tenri Fajriani. "PENYULUHAN PEMANFAATAN TABLET TAMBAH DARAH SEBAGAI DETEKSI DINI PENCEGAHAN STUNTING PADA REMAJA PUTRI DI SMPN 17 BULUKUMBA." Jurnal ABDIMAS Panrita 3, no. 2 (2022): 33–38. http://dx.doi.org/10.37362/jap.v3i2.946.

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Cakupan konsumsi tablet tambah darah pada remaja putri (12-18 tahun) sebanyak 76,2 persen dan yang yang tidak konsumsi TTD sebanyak 23,8%, yang mendapatkan tablet tambah darah di sekolah sebanyak 80,9% dan yang tidak mendapatkan TTD di sekolah sebanyak 19,1%, konsumsi TTD selama setahun <52 butir sebanyak 98,6% dan yang konsumsi > 52 butir selama setahun sebanyak1,4%. Pada tahun 2018, terdapat 32% remaja usia 15-24 tahun di Indonesia yang mengalami anemia. Hal ini berarti bahwa terdapat kurang lebih 7.5 juta remaja Indonesia yang berisiko untuk mengalami hambatan dalam tumbuh kembang, ke
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18

Rokhmah, Nisa Najwa, Erni Rustiani, and Muhamad Nur Ambiya. "EFEKTIVITAS ANTIDIABETES TABLET POLIHERBAL PADA MODEL TIKUS DIABETIK." PROSIDING SERINA 1, no. 1 (2022): 21–30. http://dx.doi.org/10.24912/pserina.v1i1.15384.

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Cinnamon bark (Cinnamomum burmanii), Phaleria macrocarpa fruit, moringa leaves (Moringa oleifera L.), and bay leaves (Syzygium polyanthum) are plants that often used for the treatment of diabetes mellitus. Each plant's antidiabetic activity is known, but the plant combination's synergistic effect is not apparent. The concept of polyherbal is to increase the therapeutic effect and decrease the concentration of a single polyherbal extract. The possibility of changing the bioavailability of polyherbal products in the form of simplicia into tablet form is a big challenge. This result was to test t
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19

Meitia Sandy, Deby, and Suci Sulistyorini. "PENGETAHUAN MENINGKATKAN KEPATUHAN MENGKONSUMSI TABLET FE PADA IBU HAMIL." Jurnal Ilmiah Pamenang 5, no. 2 (2023): 67–71. http://dx.doi.org/10.53599/jip.v5i2.191.

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Abstrak Tablet Fe (zat besi) merupakan zat yang sangat essensial bagi tubuh. Pada ibu hamil konsumsi zat besi digunakan sebagai salah satu upaya penanggulangan kekurangan zat besi. Upaya ini direkomendasikan secara universal di negara-negara berkembang. Program pemerintah mengharuskan setiap ibu hamil untuk mengkonsumsi tablet zat besi selama masa kehamilan minimal 90 tablet untuk mencegah terjadinya anemia dalam kehamilan. Tujuan penelitian ini untuk mengetahui hubungan pengetahuan dengan kepatuhan dalam mengkonsumsi tablet Fe pada ibu hamil. Metode penelitian ini analitik korelatif dengan pe
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20

Melo, Vivianne V., Gessyka R. Pereira, Amanda Q. Soares, et al. "Prevalence of tablet splitting in a Brazilian tertiary care hospital." Pharmacy Practice 18, no. 2 (2020): 1910. http://dx.doi.org/10.18549/pharmpract.2020.2.1910.

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Background: Although a highly common practice in hospital care, tablet splitting can cause dose variation and reduce drug stability, both of which impair drug therapy.
 Objective: To determine the overall prevalence of tablet splitting in hospital care as evidence supporting the rational prescription of split tablets in hospitals.
 Methods: Data collected from inpatients’ prescriptions were analyzed using descriptive statistics and used to calculate the overall prevalence of tablet splitting and the percentage of split tablets that had at least one lower-strength tablet available on
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21

Akshay, Y. Sonawane Shubham S. Sonawane Jyoti Khapre. "Novel Approach And Current Applications Of Bilayer Tablet." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 1491–504. https://doi.org/10.5281/zenodo.12788774.

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The bi-layer tablet represents a new era in the successful creation of controlled release formulations with numerous characteristics to ensure successful drug delivery. Bi-layer tablets may be the best solution for avoiding chemical incompatibilities across APIs by physical separation and for developing distinct medication release patterns. A bi-layer tablet is appropriate for the sequential release of two medications in combination, as well as for the sustained release of a tablet, with one layer for rapid release as a loading dosage and the second layer for maintenance dose. As a result, the
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22

Balcha Balla, Tamrat, Nisha MaryJoseph, and Anteneh Belete. "In Vitro Evaluation of Native Taro Boloso-I Starch as a Disintegrant in Tablet Formulations." Advances in Materials Science and Engineering 2021 (December 24, 2021): 1–10. http://dx.doi.org/10.1155/2021/7576730.

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Introduction. In drug delivery, solid dosage forms, of which tablet is the commonest, are still the leading preferences. An area of research focus in tablet drug delivery is the search for tablet excipients. This study was aimed at evaluating and optimizing native Taro Boloso-I starch as a tablet disintegrant. Methods. The response surface method with central composite design (CCD-RSM) was used for the analysis and optimization of the concentration of native Taro Boloso-I starch and compression force. Wet granulation method was used for the preparation of paracetamol tablets. The response vari
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23

DuBuske, Lawrence. "Efficacy and safety of sublingual allergen immunotherapy." Allergy and Asthma Proceedings 43, no. 4 (2022): 272–80. http://dx.doi.org/10.2500/aap.2022.43.220036.

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Sublingual immunotherapy (SLIT)-tablets represent a new allergen immunotherapy option for clinicians. In North America, there are five SLIT-tablets approved for the treatment of allergic rhinoconjunctivitis (ARC). No SLIT-drops products are currently approved in the United States or Canada. This work reviewed the efficacy of the timothy grass SLIT-tablet, five-grass SLIT-tablet, ragweed SLIT-tablet, house-dust mite SLIT-tablet, and tree SLIT-tablet in patients with ARC. All the SLIT-tablets showed consistent clinical efficacy for the treatment of ARC in large, double-blind, placebo-controlled
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Wiradnyani, Luh Ade Ari, Helda Khusun, and Endang Laksminingsih Achadi. "FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEPATUHAN IBU MENGONSUMSI TABLET BESI-FOLAT SELAMA KEHAMILAN." Jurnal Gizi dan Pangan 8, no. 1 (2013): 63. http://dx.doi.org/10.25182/jgp.2013.8.1.63-70.

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ABSTRACT<br />This review aims at compiling and summarizing findings of published studies that assessed factors associated with compliance of women to take recommended iron tablets during pregnancy. The review is done in 10 published studies (8 are 2002—<br />2010 publications and 2 are 1993—1994 publications) indexed in Pubmed with the above objective. Low utilization of antenatal care/ANC services is found to be associated with low compliance as it prevents the women to receive recommended number of the iron tablets as well as decrease the opportunity of women to have encourageme
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25

Aldridge, P. K., R. F. Mushinsky, M. M. Andino, and C. L. Evans. "Identification of Tablet Formulations inside Blister Packages by Near-Infrared Spectroscopy." Applied Spectroscopy 48, no. 10 (1994): 1272–76. http://dx.doi.org/10.1366/0003702944027336.

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Near-infrared spectroscopy was evaluated as a method for nondestructively discriminating tablets containing an active drug from two placebo tablet formulations inside blister-packaged clinical supplies without removing the tablets from the blind study tablet cards. A custom sampling device was constructed to allow the spectra of individual tablets to be collected. Spectra of 165 tables were acquired over the wavelength range of 400 to 2500 nm. These tablets were of two different sizes and three formulations. The second derivatives of the spectra were calculated and randomly divided into two gr
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Yılmaz Genç, Melek Merve, and Ayça Fidan. "Children, parents and tablets: Preschool children's tablet use." Pegem Eğitim ve Öğretim Dergisi 7, no. 3 (2017): 367–98. http://dx.doi.org/10.14527/pegegog.2017.014.

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The aim of this study is to examine preschoolers' tablet use and evaluate parents' opinions concerning it. To this end, the study made use of a case study design which is a means of qualitative research. The sample of the study consists of five preschoolers and their parents. The study data was gathered with observations related to preschoolers' tablet use, examinations of the applications in children's tablets and semi-structured interviews with parents. The analysis framework for tablet use was structured based on the document review process and data concerning observations and interviews un
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Agam, Kumar Chaubey* Ashok Baghel Dinesh Sharma Yogendra Singh. "Formulation And Evaluation of Bi-Layered Tablet of Divalproex Sodium." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 501–13. https://doi.org/10.5281/zenodo.14993024.

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The pharmacokinetic advantage relies on the criterion that, drug release from the fast-releasing layer leads to a sudden rise in the blood concentration. However, the blood level is maintained at steady state as the release from sustained layer. Particularly bilayer tablets are commonly used to avoid chemical incompatibilities of formulation components by physical separation, and release profile. The tablet is the most widely used dosage form because of its convenience in terms of self-administration, compactness and ease in manufacturing.4 Tablets are solid dosage forms containing medicinal s
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Ganesh, U. Chavan* Payal V. Suradkar Trupti D. Hudekar. "A Comprehensive Review On: Tablet." International Journal in Pharmaceutical Sciences 2, no. 10 (2024): 794–805. https://doi.org/10.5281/zenodo.13936009.

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Tablets are the most commonly prescribed dosage form as offer a convenient form of drug administration provides dosage uniformity from tablet to tablet. Medicines are not just a science but an art, involving understanding the processes of life. Pharmaceutical oral solid dosage forms have been widely used for decades due to their convenience and suitability for systemic effects. Tablets, made from powders, granules, pellets, or film-coated units, are the most popular dosage form, accounting for 70% of ethical pharmaceutical preparations. They can be prepared using compression or moulding method
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Ganesh, U. Chavan1* Payal V. Suradkar2 Trupti D. Hudekar2. "A Comprehensive Review On: Tablet." International Journal in Pharmaceutical Sciences 2, no. 10 (2024): 794–805. https://doi.org/10.5281/zenodo.13963865.

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Tablets are the most commonly prescribed dosage form as offer a convenient form of drug administration provides dosage uniformity from tablet to tablet. Medicines are not just a science but an art, involving understanding the processes of life. Pharmaceutical oral solid dosage forms have been widely used for decades due to their convenience and suitability for systemic effects. Tablets, made from powders, granules, pellets, or film-coated units, are the most popular dosage form, accounting for 70% of ethical pharmaceutical preparations. They can be prepared using compression or moulding method
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30

Rajeshwari Gokul Khairnar, Ashwini Ramdas Darade, and Rupali Rajesh Tasgaonkar. "A review on tablet binders as a pharmaceutical excipient." World Journal of Biology Pharmacy and Health Sciences 17, no. 3 (2024): 295–302. http://dx.doi.org/10.30574/wjbphs.2024.17.3.0142.

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The tablet formulation contains binders that increase the inter-particulate bond power inside the tablet. Research and progress of novel accessories remains a priority for potential use as a binder in formulations tablet. Tablet binder or binding agent are the substances that are added either dry or in liquid form during wet granulation to form granules or to promote cohesive compacts for directly compressed tablets. E.g., starch, pregelatinized starch, PEG, sorbitol, and HPMC, etc. Tablet Binder and disintegrants have the opposite used in an oral solid formulation. Binder delay tablet disinte
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Rajeshwari, Gokul Khairnar, Ramdas Darade Ashwini, and Rajesh Tasgaonkar Rupali. "A review on tablet binders as a pharmaceutical excipient." World Journal of Biology Pharmacy and Health Sciences 17, no. 3 (2024): 295–302. https://doi.org/10.5281/zenodo.11365349.

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The tablet formulation contains binders that increase the inter-particulate bond power inside the tablet. Research and progress of novel accessories remains a priority for potential use as a binder in formulations tablet. Tablet binder or binding agent are the substances that are added either dry or in liquid form during wet granulation to form granules or to promote cohesive compacts for directly compressed tablets. E.g., starch, pregelatinized starch, PEG, sorbitol, and HPMC, etc. Tablet Binder and disintegrants have the opposite used in an oral solid formulation. Binder delay tablet disinte
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McDevitt, Joseph T., Andrea H. Gurst, and Yinshuo Chen. "Accuracy of Tablet Splitting." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 18, no. 1 (1998): 193–97. http://dx.doi.org/10.1002/j.1875-9114.1998.tb03838.x.

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We attempted to determine the accuracy of manually splitting hydrochlorothiazide tablets. Ninety‐four healthy volunteers each split ten 25‐mg hydrochlorothiazide tablets, which were then weighed using an analytical balance. Demographics, grip and pinch strength, digit circumference, and tablet‐splitting experience were documented. Subjects were also surveyed regarding their willingness to pay a premium for commercially available, lower‐dose tablets. Of 1752 manually split tablet portions, 41.3% deviated from ideal weight by more than 10% and 12.4% deviated by more than 20%. Gender, age, educat
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Widjayanti, Vinsensia Ivana, and Iwan Setiawan. "Formulasi Tablet Effervescent Ekstrak Sirih Cina (Peperomia pellucida L.) Dan Uji Aktivitas Terhadap Antibakteri Staphylococcus aureus." Pharmacon: Jurnal Farmasi Indonesia 19, no. 2 (2022): 115–25. http://dx.doi.org/10.23917/pharmacon.v19i2.18338.

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Chinese Betel herb (Peperomia pellucida L.) has flavonoid and saponin content compounds that can inhibit bacterial growth. The innovation of effervescent tablets used as disinfectants is not widely known in the Indonesian market. This preparation has the advantage of being easy to manufacture as a disinfectant. Chinese betel herb extract is formulated into an effervescent tablet preparation. This study aims to determine the influence on variations in the levels of binders and fillers in the physical properties of effervescent tablet preparations and determine the activity in the effervescent t
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Gorski, Stanley F., Stephen Reiners, and Michael A. Ruizzo. "Release Rate of Three Herbicides from Controlled-Release Tablets." Weed Technology 3, no. 2 (1989): 349–52. http://dx.doi.org/10.1017/s0890037x00031936.

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Six, 9, and 12-mm diam dicalcium phosphate tablets were evaluated for their release of acetochlor, metolachlor, and metribuzin. Greenhouse bioassays with Italian ryegrass demonstrated that herbicides from the smaller tablets did not control grass as long as from the larger tablets. Italian ryegrass was controlled within a 5- to 7-cm diam circle around the 12-mm diam tablet and a 5-cm diam circle around the 6-mm diam tablet. All tested herbicides responded in a similar fashion. Six-mm diam tablets released metolachlor for 11 weeks, while the 12-mm tablet was active for 28 weeks.
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Matthew, N. O. Sadiku, K. Ampah Nana, and K. Ampah Nana. "Tablet Computers." International Journal of Trend in Scientific Research and Development 2, no. 5 (2018): 1582–83. https://doi.org/10.31142/ijtsrd17115.

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Tablet computers are touch screens. They are easier to use for older people and people with disabilities. They have been proven to be very useful in the educational system because of their portability, flexibility, ease of note taking, convenient access, and multiple applications. Tablet PCs along with wireless technology can be used to change the dynamics of classroom instruction. This paper provides a brief introduction to tablet computers. Matthew N. O. Sadiku | Nana K. Ampah | Sarhan M. Musa "Tablet Computers" Published in International Journal of Trend in Scientific Research and
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Samputri, Fatma Ryalda, and Novera Herdiani. "Pengetahuan dan Dukungan Keluarga dengan Kepatuhan Konsumsi Tablet Tambah Darah pada Remaja Putri." MEDIA KESEHATAN MASYARAKAT INDONESIA 21, no. 1 (2022): 69–73. http://dx.doi.org/10.14710/mkmi.21.1.69-73.

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Latar belakang: Tablet tambah darah adalah upaya pemerintah untuk menurunkan kejadian anemia pada remaja putri. Remaja putri yang memiliki tingkat pengetahuan kurang berisiko tidak mengonsumsi tablet tambah darah. Dukungan keluarga berperan penting pada kepatuhan mengonsumsi tablet tambah darah. Tujuan penulisan literature review ini adalah untuk menganalisis pengetahuan dan dukungan keluarga dengan kepatuhan konsumsi tablet tambah darah pada remaja putri.Metode: Penelitian ini adalah penelitian literature review. Analisis penelitian ini menggunakan persamaan-persamaan antar kasus (method of a
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Ashish, Sonawane* Yashpal More Vaibhav Patil. "Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3566–74. https://doi.org/10.5281/zenodo.15478930.

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A new era in the successful creation of controlled release formulations with many properties to offer an effective drug delivery mechanism began with the introduction of bilayer tablets. Bilayer tablets are superior to conventional mouthwash, sprays, and gels. Therefore, using a bilayer pill for analgesic and anti-inflammatory purposes is rather different. Two incompatible substances can be separated using bi-layer tablets, two treatments can be released successively, or sustained release tablets with an immediate release dose in the first layer and a maintenance dose in the second layer can b
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Kosugi, Atsushi, Kok Hoong Leong, Eri Urata, et al. "Effect of Different Direct Compaction Grades of Mannitol on the Storage Stability of Tablet Properties Investigated Using a Kohonen Self-Organizing Map and Elastic Net Regression Model." Pharmaceutics 12, no. 9 (2020): 886. http://dx.doi.org/10.3390/pharmaceutics12090886.

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This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability of the resulting tablets. After preparing the model tablets with different values of hardness, they were stored at 25 °C, 75% relative humidity for 1 week. Then, measurement of the tablet properties was conducted on both pre- and post-storage tablets. The tablet properties were tensile strength (TS), friability, and disintegration time (DT). The experimental data were analyzed using a Kohonen self-organizing map (SOM). The SOM analysis successfully classified the
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Dadang Putra Mardigantara, Mikhania C. E. ,. Dewi rashati,. "PERBANDINGAN SIFAT FISIK TABLET SALUT CIPROFLOXACIN 500 MG MEREK GENERIK DAN MEREK DAGANG." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 1, no. 1 (2021): 7–12. http://dx.doi.org/10.53864/jifakfar.v1i1.5.

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The aim of this study was to compare physical properties ciprofloxacin 500 mg coated tablet generic and trademark brand. The test include weight uniformity, tablet hardness, tablet friability, and disintegration time test. Descriptive experimental design (the one-shot case study) was used as study design. Samples were taken from three generic brands and three trademarks brand ciprofloxacin 500 mg coated tablets. Samples were produced by different factories and taken by simple random sampling method. The results showed that ciprofloxacin 500 mg coated tablets generic and trademark brand are com
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K, Kulkarni, and Deokar G. "From Challenges to Advancement for Bilayer Tablet Technology as Drug Delivery System." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1676–82. https://doi.org/10.25258/ijddt.14.4.64.

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Bilayer tablet technology is in focus because it advantageous for combination therapy, for combining two different release profile and it gives patent novelty to existing dosage. Hence its advantages, challenges and applications need to be discuss. The objective of preparing a review article on bilayer tablets is multifaceted, aiming to cover challenges at formulation development to scaleup and opportunity for new product development by integrating it bilayer tablet technology with other formulation technology. With reference to all the electronic data it was found that bilayer tablets face ma
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Khan, MD Abdul Aali, M. S. Sudheesh, and Rajesh Singh Pawar. "Formulation Development and Evaluation of Oro-Dispersible Tablets Based On Solid Dispersion of Cimetidine." Journal of Drug Delivery and Therapeutics 12, no. 6-S (2022): 42–46. http://dx.doi.org/10.22270/jddt.v12i6-s.5696.

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The most common problem about conventional dosage form is dysphagia (difficulty in swallowing). So, we design a new approach in a conventional dosage form which is oral dispersible tablet. Oral dispersible tablet is also called as mouth dissolving tablet, fast dissolving tablet, or oral disintegrating tablet. Oral dispersible tablet has advantage as it quickly disintegrates into saliva when it is put on the tongue. The faster the drug disintegrates or is dissolved, the faster the absorption and the quicker the therapeutic effect of drug will be attained. The objective of present study was to f
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He, Qi, Chang Li, and WeiHao Yuan. "Tablet Press Model Analysis in Automated Production Equipment." Highlights in Science, Engineering and Technology 71 (November 28, 2023): 147–52. http://dx.doi.org/10.54097/hset.v71i.12685.

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Tablets are one of the indispensable pharmaceutical forms in healthcare, and it has been developed based on powders and pills with a long history of application. Its commonly used production equipment is a tablet press, which directly presses pharmaceutical powder granules into tablets. This paper uses the traditional tablet press as a model to introduce the six-bar mechanism, reducer, and motor part. Based on real data, the rush return characteristics, pressurization and holding characteristics of the six-bar mechanism are analyzed. Finally, the shortcomings of traditional tablet presses are
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Bracken, Louise, Emma McDonough, Fiona Wilson, et al. "P001 Creating acceptable tablets (CAT) – a feasibility study to assess the swallowability and acceptability of different sized placebo tablets in children and young people: an interim analysis." Archives of Disease in Childhood 104, no. 7 (2019): e2.3-e2. http://dx.doi.org/10.1136/archdischild-2019-nppc.11.

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AimTo determine the feasibility of investigating the swallowability and acceptability of different sized placebo tablets in children and young people (CYP) aged 4–12 years and estimate consent/recruitment rates for a future study.MethodsParticipants were asked to swallow three different sized placebo tablets; 6mm, 8mm and10mm in a standardised order, smallest to largest. The recruitment target is 50 children, including both healthy children and NHS inpatients/outpatients. Following informed consent participants were shown a short video demonstrating how a tablet can be swallowed. The researche
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Haryono, Ika Avrilina, and Noval Noval. "Formulasi dan Evaluasi Tablet Effervescent dari Ekstrak Buah Tampoi (Baccaurea macrocarpa)." Jurnal Surya Medika 7, no. 2 (2022): 34–44. http://dx.doi.org/10.33084/jsm.v7i2.3201.

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Tampoi is one of the many plants found in East Kalimantan, has secondary metabolic content in the form of saponins, flavonoids, and alkaloids, and has antioxidant activity. The antioxidants produced by the human body are not sufficient to fight free radicals, therefore the body requires the intake of antioxidants from the outside, so to help increase public interest in consumption, researchers are interested in making preparations in the form of extracts and formulated as effervescent tablets from tampoi fruit extract which are useful as antioxidants and increase immunity. The purpose of this
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45

Simbolon, Jenni Novita, Kismi Asih Adethia, Eka Falentina Tarigan, Ngarap Muliana Harahap, and Meviani Putri. "Analisis Faktor Yang Mempengaruhi Ketidakpatuhan Ibu Hamil Dalam Mengkonsumsi Tablet Fe." Indonesian Health Issue 2, no. 2 (2023): 97–107. http://dx.doi.org/10.47134/inhis.v2i2.48.

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Latar Belakang: Upaya mencegah anemia pada ibu hamil dengan mengkonsumsi tablet Fe.Data Kemenkes Tahun 2019, cakupan ibu hamil mendapat tablet Fe 64,0 %.Tujuan: Analisis Faktor Mempengaruhi Ketidakpatuhan Ibu Hamil Mengkonsumsi Tablet Fe. Metode: Jenis penelitian ini observasional analitik, desain penelitian Cross Sectional. Sampel penelitian berjumlah 56 orang, tehnik pengambilan sampel total sampling. Hasil: Mayoritas ibu hamil yang tidak patuh mengkonsumsi Tablet Fe adalah pengetahuan kurang sebanyak 9 orang (16,1 %). Diperoleh p value 0,000 < 0,05 terdapat hubungan Pengetahuan dengan Ke
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46

Tahaineh, Linda M., and Shadi F. Gharaibeh. "Tablet Splitting and Weight Uniformity of Half-Tablets of 4 Medications in Pharmacy Practice." Journal of Pharmacy Practice 25, no. 4 (2012): 471–76. http://dx.doi.org/10.1177/0897190012442716.

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Background: Tablet splitting is a common practice for multiple reasons including cost savings; however, it does not necessarily result in weight-uniform half-tablets. Objectives: To determine weight uniformity of half-tablets resulting from splitting 4 products available in the Jordanian market and investigate the effect of tablet characteristics on weight uniformity of half-tablets. Methods: Ten random tablets each of warfarin 5 mg, digoxin 0.25 mg, phenobarbital 30 mg, and prednisolone 5 mg were weighed and split by 6 PharmD students using a knife. The resulting half-tablets were weighed and
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Patimah, Patimah, Junie Suriawati, and Siti Rahayu Rahmawati. "Development Of Caulis Extract (Tinospora Crispa (L.) Hook. F. & Thomson As Plasmodium In Preparations Tablets." SANITAS : Jurnal Teknologi dan Seni Kesehatan 9, no. 1 (2018): 6–15. http://dx.doi.org/10.36525/sanitas.2018.2.

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Brotowali (Tinospora crispa (L.) Hook. f. Thomson is a wild plant & in the Woods, fields or planted page near the fence, and the usual planted as medicinal plants. The entire plant (roots, stems, and leaves) has a bitter taste that can be used as a traditional medicine as Plasmodium. This research aims to make the tablet dosage of Caulis extract with gelatin Binder and polivenilpirolidon materials that meet the requirements of the physical quality of a tablet that is acceptable. Prior to the manufacture of tablets do extract raw materials testing which includes the determination of the lev
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P, Narayana Raju, Prakash K, Rama Rao T, B. C. S. Reddy, Sreenivasulu V, and Lakshmi Narasu M. "Effect of Tablet Surface Area and Surface Area/Volume on Drug Release from Lamivudine Extended Release Matrix Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 3, no. 1 (2010): 872–76. http://dx.doi.org/10.37285/ijpsn.2010.3.1.11.

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The purpose of this study was to investigate the influence of tablet surface area/ volume (SA/Vol) on drug release from extended-release matrix tablets of lamivudine prepared with hydroxy propyl methylcellulose (HPMC). Highly soluble drug such as lamivudine was utilized in this study to give predominantly diffusion-controlled release. Drug release from HPMC matrix tablets with similar values of SA/Vol was comparable within the same tablet shaped tablet. Tablets having the same surface area but different SA/Vol values did not result in similar drug release, tablets with larger SA/Vol values had
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Nurhikmah, Wilda, Erni Rustiani, and Dania Triska Puspita. "PENGEMBANGAN SEDIAAN TABLET ESTROGENIK DARI EKSTRAK RUMPUT KEBAR (Biophytum petersianum) MENGGUNAKAN VARIASI KONSENTRASI PENGIKAT PVP K-30." Jurnal Ilmiah Manuntung 9, no. 2 (2023): 111–19. http://dx.doi.org/10.51352/jim.v9i2.661.

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Kebar grass (Biophytum petersianum Klotzsch) contains steroid, saponins, flavonoids, alkaloids, and triterpenoids. The use of Kebar grass extract can increase the development of follicles because it contains saponins which are the basic ingredients for the synthesis of steroid hormones and can improve the performance of reproductive system. This study aims to determine the quality the tablets made from Kebar grass extract with varying concentrations of PVP K-30 binder. Tablets were made in 3 formulas with varying concentrations of PVP K-30 as a binder, namely 2% (F1), 3% (F2), and 4% (F3). Met
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Mukri, A. K., J. H. Tan, S. M. Tahir, M. S. Anuar, and S. M. Yusoff. "Compaction behaviour of mannitol-cocoa powder mixtures and their resulting tablet strength and disintegration characteristics." Food Research 5, S1 (2021): 182–87. http://dx.doi.org/10.26656/fr.2017.5(s1).038.

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Cocoa powder is an important ingredient in the confectionery industry and, mannitol is an alternative sugar alcohol. In this work, mannitol powder was mixed with cocoa powder and compacted into tablet form via the uniaxial die compaction process. The frictional, compaction, tablet mechanical and disintegration properties were studied due to their importance in characterizing the behaviour of the tablets during processing and its final product characteristics at varying mannitol contents. The composition of mannitol in the mannitol-cocoa tablet varied at 95% w/w, 50% w/w and 5% w/w, while pure
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