Tesis sobre el tema "The birth of beer"

The literature consistently reports a lack of support for birth mothers following their child being taken into care or adopted (Logan, 1996; Schofield, 2009; Schofield, 2010). This is despite consistent evidence of the long-term consequences that the removal of children has upon their mental health (Condon, 1986; Wells, 1993; Logan, 1996). O’Leary-Wiley & Baden (2005) write, ‘Birth parents are the least studied, understood, and served members of the adoption triad.’ The aim of the study was to explore: the experience of separation, sense of identity following separation, experience of contact and experience of support through the process. Semi-structured interviews were conducted with seven mothers who were recruited from birth mother support groups. The transcripts of the interviews were analysed using Interpretative Phenomenological Analysis (IPA). Four main themes emerged across the participants’ accounts: ‘No one in my corner’, ‘Disconnecting from emotion’, ‘Renegotiating identity’ and ‘The children are gone, but still here’. The findings contribute to our understanding of the experiences of birth mothers and are discussed within a range of psychological theories. Implications for clinical psychology are considered.

Orientador: Guilherme de Paula Nogueira
Coorientador: Luzia Helena Queiroz
Banca: Gisele Zoccal Mingoti
Banca: Rafael Silva Cipriano
Resumo: Os animais congênicos possuem apenas uma região específica do cromossomo transferida de uma linhagem para outra através de cruzamentos monitorados por análises genéticas. Essa metodologia foi utilizada para produzir linhagem congênica de bovinos da raça Nelore carreando o polimorfismo no gene da miostatina proveniente do Belgian Blue. O objetivo desse trabalho foi comparar o peso ao nascimento, incidência de partos distócicos e taxa de mortalidade neonatal em animais de 3 variações genéticas para o gene da miostatina (homozigotos sem o polimorfismo, heterozigotos e homozigotos mutados). Animais homozigotos sem a mutação nasceram com 31,19 kg ± 0,32 kg, os heterozigotos com 35,82 kg ± 0,32 kg (diferença de 4,63 kg) e os homozigotos mutados nasceram com 40,46 ± 0,32 kg, com acréscimo médio de 9,26 kg acima dos bezerros homozigotos não mutados (p=2 x 10-16). Além disso bezerros machos apresentaram um acréscimo de 1,55 Kg em relação as fêmeas. A taxa de distocia dos bezerros homozigotos sem o polimorfismo e dos heterozigotos foram de 5,4% e 5,7%. A taxa de mortalidade dos bezerros homozigotos sem o polimorfismo e dos heterozigotos foram de 5,4% e 5,2%, dentro das normalidades esperadas. Entretanto, animais homozigotos mutados apresentaram altas taxas de distocia 47,5% e de mortalidade de bezerros 37,3%. Os dados indicam que a mutação no gene da miostatina quando em heterozigose gera um aumento de peso ao nascimento sem causar aumento de distocia ou de mortalidade neonatal. Conclu... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Congenic animals have only one chromosome specific region transferred from one lineage to another through crosses monitored by genetic analysis. This methodology was used to produce a Nellore cattle congenic line carrying the myostatin gene polymorphism from Belgian Blue. The objective of this study was to compare birth weight, incidence of dystocy and neonatal mortality rate in animals from the 3 genetic variations for the myostatin gene (homozygotes without the polymorphism, heterozygotes and mutated homozygotes). Homozygous animals without the mutation were born with 31,19 ± 0,32 kg, heterozygotes werte born with 35,82 ± 0,32 kg, a difference of 4,63 kg and the mutated homozygotes were born with 40,46 ± 0,319 kg, with an increase of 9,26 kg above homozygotes without the polymorphism calves (p = 2*10-16). In addition, male calves showed an increase of 1,55 kg in relation to females. The rates of dystocia of calves homozygous within polymorphism and heterozygotes were 5,4% e 5,7%. The rates of mortality of calves homozygous within polymorphism and heterozygotes were 5,4% e 5,2%, within expected normalities. However, mutated homozygous animals had high rates of dystocia (47.5%) and calves mortality (37.3%). The data indicate that mutation in the myostatin gene when in heterozygosis results in an increase birth weight without causing increased dystocia or neonatal mortality. We conclude that animals heterozygotes can be produced on a large scale, and may be an advantageous str... (Complete abstract click electronic access below)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Os animais congênicos possuem apenas uma região específica do cromossomo transferida de uma linhagem para outra através de cruzamentos monitorados por análises genéticas. Essa metodologia foi utilizada para produzir linhagem congênica de bovinos da raça Nelore carreando o polimorfismo no gene da miostatina proveniente do Belgian Blue. O objetivo desse trabalho foi comparar o peso ao nascimento, incidência de partos distócicos e taxa de mortalidade neonatal em animais de 3 variações genéticas para o gene da miostatina (homozigotos sem o polimorfismo, heterozigotos e homozigotos mutados). Animais homozigotos sem a mutação nasceram com 31,19 kg ± 0,32 kg, os heterozigotos com 35,82 kg ± 0,32 kg (diferença de 4,63 kg) e os homozigotos mutados nasceram com 40,46 ± 0,32 kg, com acréscimo médio de 9,26 kg acima dos bezerros homozigotos não mutados (p=2 x 10-16). Além disso bezerros machos apresentaram um acréscimo de 1,55 Kg em relação as fêmeas. A taxa de distocia dos bezerros homozigotos sem o polimorfismo e dos heterozigotos foram de 5,4% e 5,7%. A taxa de mortalidade dos bezerros homozigotos sem o polimorfismo e dos heterozigotos foram de 5,4% e 5,2%, dentro das normalidades esperadas. Entretanto, animais homozigotos mutados apresentaram altas taxas de distocia 47,5% e de mortalidade de bezerros 37,3%. Os dados indicam que a mutação no gene da miostatina quando em heterozigose gera um aumento de peso ao nascimento sem causar aumento de distocia ou de mortalidade neonatal. Concluímos que heterozigotos podem ser produzidos em larga escala, podendo ser uma estratégia vantajosa para aumentar a produtividade da pecuária de corte.
Congenic animals have only one chromosome specific region transferred from one lineage to another through crosses monitored by genetic analysis. This methodology was used to produce a Nellore cattle congenic line carrying the myostatin gene polymorphism from Belgian Blue. The objective of this study was to compare birth weight, incidence of dystocy and neonatal mortality rate in animals from the 3 genetic variations for the myostatin gene (homozygotes without the polymorphism, heterozygotes and mutated homozygotes). Homozygous animals without the mutation were born with 31,19 ± 0,32 kg, heterozygotes werte born with 35,82 ± 0,32 kg, a difference of 4,63 kg and the mutated homozygotes were born with 40,46 ± 0,319 kg, with an increase of 9,26 kg above homozygotes without the polymorphism calves (p = 2*10-16). In addition, male calves showed an increase of 1,55 kg in relation to females. The rates of dystocia of calves homozygous within polymorphism and heterozygotes were 5,4% e 5,7%. The rates of mortality of calves homozygous within polymorphism and heterozygotes were 5,4% e 5,2%, within expected normalities. However, mutated homozygous animals had high rates of dystocia (47.5%) and calves mortality (37.3%). The data indicate that mutation in the myostatin gene when in heterozygosis results in an increase birth weight without causing increased dystocia or neonatal mortality. We conclude that animals heterozygotes can be produced on a large scale, and may be an advantageous strategy to increase the productivity of beef cattle.

The “Kalevala” is one of the most beautiful and archaic epos in world literature. It is composed from ancient Finnish poems by Elias Lönnrot, son of a poor village tailor, who started his career as a medical doctor, but who became a Professor of the Finnish language. The “Kalevala” is supposed to be a central source of identity for a nation that has been awaking to a consciousness of itself and also Finland’s most important contribution to world literature. Archaeological and linguistic data point out that in the prehistory period the Finno-Ugric tribes had near relations with the Balts. Their contacts, even coexistence, continued for a long time. In the process of cultural assimilation the more advanced culture of the Balts dominated, and the evidence of this can be seen in the Balt loanwords for social, administrative and agricultural innovations. A lot of names of incipient village, agrarian life in Finish appear to derive from ancient Balt loan. From the Balts the Finns borrowed even the most important terms of relationship, such like family, sister, daughter, cousin, daughter-in-law. That is why in the folklore of the Balts and the Finns we can find some parallels and affinities. In comparison Finnish national epos with Lithuanian folk songs there is seen that obvious affinities have the rune of the great oak, the rune of Aina, the episode about the birth of beer. Some parallels with Lithuanian folk songs and ballads also can be seen in the rune of Kulervo. Genetic... [to full text]

Includes bibliographical references.
[Background] Research in adults and older children has shown an association between Mycobacterium tuberculosis and helminth infection, with those infected with helminths at greater risk of tuberculosis. This association is believed to be on the basis that chronic helminth infection can result in a functional impairment of the immune response that is necessary to clear or control infection by Mycobacterium tuberculosis (Elias et al. 2001; Rook et al. 2006; Fincham 2001). It is thus possible that the introduction of regular deworming programmes in a vulnerable population of children under the age of five years could assist their immune systems to ward off tuberculosis infection and reduce the risk of tuberculosis disease in such a population. A randomised controlled trial to compare two methods of administering bacille Camlette-Guerin (BCG) vaccination to newborns from a high tuberculosis risk population provided an opportunity to test this hypothesis in a sub-study. [Objective] The objective of this study is to determine if young children in a high-risk tuberculosis population who have been vaccinated with BCG at birth and have been treated for helminth infection are at lower risk of tuberculosis disease than children who have been vaccinated with BCG at birth but not treated for helminth infection. [Method] A case control study nested within a cohort recruited for a separate randomised control trial to compare two methods of administering BCG vaccination was carried out. Children who presented to their local clinic or hospital with symptoms of tuberculosis or a history of exposure to tuberculosis were admitted to a case verification (CV) ward for investigation of tuberculosis. Investigation of tuberculosis included a detailed history, including past helminth treatment, physical examination, tuberculin skin test, chest radiograph, gastric washing and induced sputum for culture of tuberculosis and clinical examination. A diagnostic algorithm was developed by specialist physicians and biostatisticians to classify the children into one of five tuberculosis categories. A total of 510 children (median age 18.13 months) were included in the primary analysis of this case control study. Those defined as cases were the 328 classified as "definite or probable TB" and 182, classified as "not TB", comprised the control group. Those classified as "possible TB" or "unlikely TB" were excluded. A secondary analysis was performed that included the 337 children who had been classified as "unlikely TB" with the controls resulting in a total of 847 children (median age 18.37 months). The 328 children classified as "definite or probable TB" were defined as cases and the 519 classified as "unlikely or not TB" comprised the control group. Univariate analysis was used to explore a possible relationship between tuberculosis and helminth treatment using all the variables in the sub-study (n=510 primary analysis; n=847 secondary analysis). For both the primary and secondary analysis a multivariate logistic regression model was built using a reduced sample that had a complete set of data for all the variables: primary analysis (n=435); secondary analysis (n=724). This final model was then fitted on a more complete sample as the final variables selected had fewer missing data for the observations: primary analysis (n=493); secondary analysis (n=822). [Result] A total of 35.69% of the study sample in the primary analysis had been treated for helminth infection. The proportion of children who had been treated for helminth infection was similar in the cases and controls (35.98% and 35.16% respectively). Univariate logistic regression showed no association between tuberculosis and treatment for helminth infection: [odds ratio (OR) 1.04; 95% confidence interval (CI) 0.71 - 1.51]. Multivariate analysis adjusted for the effect of nutritional status, recorded as height for age z score (haz), number of occupants sharing the same dwelling as the child, gender and birth site showed a similar result: (OR 1.03; 95% CI 0.69 " 1.53). The OR is very close to 1 with a 95% CI that includes 1, which indicates that there is not a statistically significant association between tuberculosis and helminth treatment. In the secondary analysis, a total of 38.61% of the study sample had been treated for helminth infection. In this analysis the proportion of children who had been treated for helminth infection showed a difference between the cases and controls (35.98% and 40.27% respectively). Univariate logistic regression showed a 17% relative reduction in tuberculosis odds but this was not a statistically significant result: (OR 0.83; 95% CI 0.63 " 1.11). Multivariate analysis adjusted for the effect of haz, number of children sharing the same dwelling as the child and gender, showed a similar result: (OR 0.85; 95% CI 0.63 " 1.15). [Conclusion] The primary analysis of this observational study does not support the hypothesis that helminth treatment reduces the risk of tuberculosis disease in young children in a high-risk tuberculosis population. Although the secondary analysis showed a 15% relative reduction in tuberculosis odds after adjusting for the effect of haz, number of occupants sharing the same dwelling as the child and gender, this was not a statistically significant result. [Final Conclusion] This study does not support the hypothesis that helminth treatment reduces the risk of tuberculosis disease in young children in a high-risk tuberculosis population.

The goal of the project is to design a plant that is capable of converting feedstock of primarily sorghum into a gluten-free beer. This product is intended to be sold as a replacement of malt based beers for consumption by those who suffer from celiac disease or other gluten intolerances. The waste streams from this process include spent grains and yeast, and will be given to ranchers for the use as animal feed. This beer is created through a standard fermentation process. This includes mashing, boiling, filtering, fermenting, maturing, and packaging for distribution. A process hazard analysis was conducted to identify and help reduce safety and environmental hazards. An economic analysis showed that the plant's net present value for a project life of ten years with an interest rate of 15% is $1.08 million; therefore, it was recommended that the plant be built at this time. Future work includes scaling up the process for better profit margins, and finding more ways to reduce the amount of water and energy used.

Wine & Beer tells the story of childhood friends Brian and Vic who, after spending some time apart, deal with the tensions of sexual orientation after they attempt to renew their friendship. At the beginning it seems that Vic's sexuality will not be a problem, but after the two friends hang out in a local bar, Brian realizes his hometown is not as tolerant as he is. The couple is faced with family and social concerns, which goes from the argumentative to the violent. As the main characters try to mingle with the conservative town, they soon find themselves looked upon by a small town resistant to change. This 35-minute film explores homophobia and violence in small town USA.

The purpose of this study is to examine beer reviews to see what descriptors are identified and used to describe beers. Also, the domains APPEARANCE, AROMA, FLAVOUR, MOUTHFEEL and OVERALL IMPRESSION are analysed. The theoretical framework stems from the genre of wine reviews, with additional backbone from beer sensory analysis and established beer terminology. Through analysis of 27 beer reviews in three leading beer magazines, the study shows that most typically object descriptors and property descriptors relating to the raw materials are used. In terms of domains, APPEARANCE and MOUTHFEEL have few descriptors, whilst AROMA and FLAVOUR have a higher number of descriptors and more categories. The domain with more process related and human-like descriptions, as well as more elaborate expressions to entice the consumer, is OVERALL IMPRESSION.

Beer is by far the most widely consumed alcoholic beverage in the world. Moderate alcohol consumption in general has been inversely associated with incident cardiovascular disease in observational studies. However, it has been suggested that fermented beverages such as red wine and beer may confer greater protective effects than spirits owing to their higher polyphenolic content. Polyphenols are secondary plant metabolites that are not essential for short-term health status, however there is increasing evidence that long-term intake may reduce the incidence of chronic diseases such as cancer, type-II diabetes, cardiovascular diseases and neurodegenerative diseases. Beer phenolic profile is very diverse, most of the beer polyphenols come from malt, and the rest come from hops used during brewing. However, although hop polyphenols in beer are found in low concentrations, they are very specific to beer since they are not detected in other foods. Most techniques used in assessing the diet followed by individuals are based on self-reporting questionnaires, which are liable to systematic bias by factors such as age, gender, social desirability and approval. In this thesis, we aim to evaluate whether regular and moderate beer and non-alcoholic beer consumption may reduce cardiovascular disease risk. To assess beer intake one of the main objectives of this thesis was to find a reliable biomarkers of beer consumption, and for this purpose we developed and validated a new method to determine hops polyphenols (prenylflavonoids). We evaluated the effects of ethanol and the phenolic compounds of beer on classical and novel cardiovascular risk factors with an interventional nutritional trial with participants at high cardiovascular risk. Moreover, in a large, multicenter, randomized, parallel group we performed a prospective study aimed at assess the differential associations of wine, beer and spirit consumption with all-cause mortality and incidence of cardiovascular events.

This thesis examines the ways in which rural, national, and urban spaces become gendered through the practices and representations of beer drinking in New Zealand. Critical social theory combined with feminist poststructuralist debates on identities provides the theoretical framework for this research. Two focus groups with Pākehā beer drinkers aged between 18 - 30 years old were conducted; one consisting of six males and the other consisting of six females. Critical textual analysis was also undertaken on five beer advertisements representing the most popular beer brands in New Zealand; Tui, Lion Red, Waikato and Speight's. Three points frame the analysis. First, I examine rural and national gendered identities associated with beer drinking. New Zealand's beer drinking cultures are constructed within rural discourses of masculinity. There is not a single masculinity present in New Zealand's beer drinking cultures, rather there are multiple and conflicting masculinities. I suggest that through the need to constantly perform their identity, men create a rural hegemonic masculinity that is both hard, yet vulnerable. I argue that the femininities constructed within these spaces are used to enhance and further enable the hard, yet vulnerable, rural masculinity. Second, within urban spaces of beer drinking - such as the office, nightclub, clubrooms and home - homosexuals, metrosexuals and women are 'othered'. These identities are defined in relation to the hegemonic norm - 'Hard Man' masculinity - in negative ways. Furthermore, some women perform a hyper masculine identity in order to be included in these beer-drinking spaces. Finally, I examine the ways in which hegemonic gendered identities in rural, national and urban spaces may be resisted and subverted. I use contradictions from my focus group participants to unsettle the 'Hard Man' masculinity of New Zealand's beer drinking cultures.

The diploma thesis focuses on marketing communication of Craft Beer & Food pub U Vašinů. The first part is focused on theoretical knowledge of marketing and marketing mix. The second part contains an analysis of the environment and the current marketing communication. In the last part suggestions are presented to improve the current situation, which are based on analyzes.

The bitterness of beer remains one of its most important flavour attribute. However, complexity surrounding bitterness perception alone represents a significant challenge in its understanding, in addition to other factors relating to production processes and raw materials used in making beer. The aim of this research was to better understand beer bitterness in terms of its intensity and quality, and how hopping technology (e.g. quantity and time of hop addition during the brewing process), hop aroma and variety may effect perceived bitterness intensity and quality. This project combined both analytical and sensorial analysis, and used statistical techniques to identify the key compounds driving bitterness perception. Analytical techniques were employed to quantify bitterness-contributing compounds and analytical bitterness units in beers alongside descriptive analysis of perceived sensory bitterness. Perceived sensory bitterness (both qualitative and quantitative) was assessed using a purpose developed list of well-defined bitterness attributes, to aid the characterisation of bitterness quality in beers. The impact of cross-modal flavour interactions on the perception of beer bitterness intensity and qualities was also investigated at varying analytical bitterness levels. Lastly, the effect of hop variety, and how this significant raw material affects perceived bitterness quality was also investigated using three distinctively different hop varieties (Hersbrucker, East Kent Goldings and Zeus). Results revealed a significant impact of the analytical profiles of beers, derived from the type of hop products and hopping technology adopted in beer production, on the perceived bitterness quality of beer. In general, beers high in hop acid compounds and polyphenols were, as expected, perceived to be higher in bitterness intensity. The results further showed that bitterness intensity also played a role in the perception of bitterness quality i.e. whether the beer was ‘harsh’, ‘lingering’ or ‘round’. However, beers high in these compounds were not always of ‘negative’ bitterness quality, and correspondingly lower amounts of these compounds did not always result in ‘positive’ bitterness qualities in beer. Results on the impact of cross-modal flavour interactions showed that hop aroma plays a crucial role in beer bitterness perception, and can modify the perception of bitterness intensity and quality as well as temporal profiles of bitterness in beer depending on analytical bitterness levels. The investigation into the impact of hop variety on perceived bitterness quality revealed hop-derived bitterness profiles relating to individual hop varieties, and further suggests that careful selection of the hop variety used for brewing is important for controlling perceived bitterness quality. This research provides a comprehensive interdisciplinary approach to understanding perceived beer bitterness and its associated qualities, with findings suggesting that besides bitterness intensity, the quality and overall impression of bitterness as perceived by consumers are significantly influenced by raw materials, production processes and other factors such as aroma which might be overlooked by brewers - but are likely to be significant for consumer preference and the success of a brand.

Objetivo: Investigar e implementar un proyecto de negocio sostenible de cerveza artesanal para personas de 18 a 50 años de edad de nivel socioeconómico A y B que vivan en Lima moderna. Dicho proyecto es un negocio con fines de lucro por lo cual se recibe efectivo por parte de los clientes como muestra de que el proyecto ha sido satisfactoria y listo para ponerla en marcha; Método: Estudio cuantitativo y cualitativo para poder determinar el nivel de aceptación del público mediante experimentos que sustentan nuestro proyecto. Además, se realizaron entrevistas al público objetivo y un estudio de tamaño de mercado para averiguar el número del segmento. Por último, se propuso la proyección del proyecto a lo largo de 3 años para determinar la escalabilidad del negocio con el fin de cumplir los objetivos planteados en relación a la operatividad, recursos humanos, marketing, responsabilidad social empresarial y la parte financiera del proyecto; Resultados: Al realizar los experimentos y el concierge, se pudo validar nuestros supuestos y poner en marcha la venta de las cervezas. Además, la aceptación de la marca en las personas fue la mejor lo que repercute en un negocio escalable; Conclusiones: Se sintetiza que el proyecto incluyendo los temas abordados en el curso para la realización del trabajo, los experimentos, de gran utilidad para tener un soporte de estudio, el grupo de trabajo, distribución de cada acción a realizar, y los clientes, con quienes la interacción y comunicación seguirá después del curso para emprender el proyecto.
Objective: Investigate and implement a sustainable craft beer business project for people between 18 and 50 years of age of socioeconomic status A and B who live in modern Lima. Said project is a for-profit business for which cash is received from clients as proof that the project has been satisfactory and ready to start; Method: Quantitative and qualitative study to determine the level of public acceptance through experiments that support our project. Additionally, target audience interviews and a market size study were conducted to find out the segment number. Finally, the projection of the project over 3 years was proposed to determine the scalability of the business in order to meet the objectives set in relation to operations, human resources, marketing, corporate social responsibility and the financial part of the project; Results: By carrying out the experiments and the concierge, it was possible to validate our assumptions and start the sale of the beers. In addition, the acceptance of the brand in people was the best which had an impact on a scalable business; Conclusions: It is synthesized that the project including the topics addressed in the course to carry out the work, the experiments, very useful to have a study support, the work group, distribution of each action to be carried out, and the clients, with who the interaction and communication will follow after the course to undertake the project.
Trabajo de investigación

This is a study of 'beer drinks' among Xhosa people living in the Shixini administrative area of Willowvale district, Transkei. Beer drinks are defined as a 'polythetic' class of events distinguishable from other kinds of ceremonies and rituals at which beer may be consumed, and an attempt is made to outline their major characteristics. A detailed description of the way in which beer drinks are conducted is provided in Chapter 3, with emphasis on the symbolism involved in the allocation of beer, space and time, and on the speech events (including formal oratory) that occur. The main theoretical argument is that beer drinks may be regarded as 'cultural performances' in which social reality or 'practice' is dramatised and reflected upon, enabling people to infuse their experience with meaning and to establish guidelines for future action. This is achieved by relating social practice to cultural norms and values, in a dynamic rather than a static manner. It is demonstrated that the symbolism involved in beer drinking is highly sensitive to the real world and adjusts accordingly, which means that 'culture' is continually being reinterpreted. Despite poverty, a degree of landlessness and heavy reliance on migrant labour, Shixini people maintain an ideal of rural selfsufficiency and are able to partly fulfill this ideal, thereby maintaining a degree of independence and resistance to full incorporation into the wider political economy of southern Africa. They achieve this largely by maintaining a strong sense of community and of household interdependence, linked to a sense of Xhosa tradition. It is this aspect of social practice, manifested in a variety of forms - work parties, ploughing companies, rites of passage, and so on - that is dramatised, reflected upon and reinforced at beer drinks. In a definite sense then, beer drinks may be regarded as a response and a way of adapting to apartheid, and this study one of a community under threat.

Background: Microbreweries are a rapid and emergent alternative in the alcoholic beverage industry. Understanding resource selection, development, and management with their institutional context and capital are critical for microbreweries to develop sustained competitive advantage in a difficult industry. Therefore, using Oliver’s (1997) and Bresser and Millonig’s (2003) integration of resource capital and institutional capital, the researchers identified a gap in the literature and were interested in exploring how Swedish microbreweries select and manage resource and institutional capital in their competitive context and identify challenges to existing literature.                  Purpose: The purpose of this study is to explore and investigate how Swedish microbreweries select, develop, and manage institutional and resource-based capital. The study looks to explain the internal strategy process and factors affecting the microbrewery’s decisions.     Method: The study is an exploratory approach by combining existing theoretical frameworks and empirical data. Empirical data was collected through a qualitative research method consisting of seven semi-structured interviews and analysed with the thematic analysis technique.   Conclusion: The authors propose an amendment to Oliver’s (1997) model that links the empirical data and existing literature. In this context, collaborations and brewery networks are an important overarching dynamic that influences the procurement and management of resource capital and institutional capital. The dominant nature of collaborations and brewery networks is instrumental in the success of the microbrewery in question as it provides access to valuable resources and knowledge development crucial to achieving a sustained competitive advantage. This model can be used in the understanding of the overlapping factors facing the Swedish microbrewing industry.

Foster parents are a vital component to the child welfare system and play an important role, one of which is supervising parental visitation (Muniz, 2018; Neil et al., 2003). With visitation as the primary intervention for family reunification (Haight et al., 2003), foster parents and birth parents are more than likely to interact with one another at some point in time. The purpose of this research study was to examine if foster parent attitudes toward birth parents influence foster parent attitudes toward birth parent visitation. Data was collected from 40 participants, 36 females and 4 males, from a foster family agency based in California and Texas. The study used a survey design and questions were distributed in a group setting, a mailed hard-copy, and a web survey link. The study’s findings revealed that that when foster parents had a more positive attitude toward birth parents, they had a more positive attitude toward birth parent visitation. The study concludes with recommendations for public child welfare agencies and foster family agencies to develop trainings for foster parents and for social workers to increase efforts in assisting foster parents and birth parents build cooperative relationships.

The project aim is to determine if good quality DNA can be extracted from barley, malt and hop, ingredients used in beer brewing. Good quality DNA is important in DNA fingerprinting techniques which can be used for identification of ingredients. The 3 methods tested are the cetyltrimethylammonium bromide (CTAB) method, QIAGEN DNeasy Plant Mini Kit and Meyer’s method as published in 1996 with QIAGEN DNeasy Plant Mini Kit in combination. To evaluate the DNA quality after extraction we used 3 different techniques:

(i) spectrophotometry to estimate purity by using the ratio A260/A280; (ii) agarose gel electrophoresis after DNA extraction to determine the success of the extraction and evaluate the amount of high molecular weight DNA and degradation; and (iii) the polymerase chain reaction with 4 different primer pairs, together with agarose gel electrophoresis, to determine if the extracted DNA could be used in downstream applications, see the effect of inhibitors and estimate the fragmentisation of the DNA. The results achieved using the above mentioned methods were then used to evaluate the success of each of the extraction methods in their function of extracting high quality DNA from barley, malt and hop as well as determining whether the treatment of the ingredients has an effect on the DNA quality.

Texas Instruments is the world leader in digital signal processing and analog technologies. In order to showcase two new products (the ADS1220 and DAC8760), the company created a project to cool and dispense beer automatically. The ability to successfully display the accuracy and precision of their new technologies is key in the design and manufacture of loop powered sensor field transmitters, utilizing high precision data converter integrated circuits. These transmitters are used to monitor temperatures at different locations within the beer cooling system through the use of Resistance Temperature Device (RTD) sensors. The sensors, along with other industrial instrumentation, interface with a Programmable Logic Controller (PLC) to dispense beer at the appropriate temperature and fill a receptacle to the desired level. The water, cooled by the Thermal-Electric Coolers (TECs), is re-circulated through a water bath that houses the beer coil and absorbs the heat dissipated by the beer at a rate of 37°F/hr. Additionally, system status and settings can be seen and changed by a user through an iPad GUI application. This temperature control application highlights TI’s accurate and precise technologies for designers in the process control industry.

For centuries the world’s biggest breweries, including Anheuser-Busch InBev and MillerCoors, have been producing America’s favorite beers like Budweiser and Coors Light. However, more recently smaller, craft breweries have seen significant expansion as a growing number of Americans are drinking craft beers. How has this recent trend affected the beer market in the United States? More specifically, how has the recent success of craft breweries affected Anheuser-Busch InBev and MillerCoors? I examine the economic factors that have led to craft beer’s success in a highly competitive market, and further, how this success has impacted Anheuser-Busch InBev and MillerCoors. My study reveals that the premier quality of craft beer has distinctively separated itself from the traditional American lagers, like Coors and Bud Light. Furthermore, as the United States has experienced economic growth, more and more Americans are choosing craft beers over these American lagers. In final, I examine and explain Anheuser-Busch InBev and MillerCoors’ recent multi-billion dollar investments into the craft beer industry.

A gas chromatographic method for the routine analysis of volatile and semi-volatile sulphur compounds in beer was developed. Various selective and specific detectors, capillary columns and methods of sample preparation were compared. The combination offering the best sensitivity and stability consisted of solid phase microextraction (SPME) as the sample preparation step; a combined polar/non-polar chromatographic column; and a pulsed flame photometric detector (PFPD). All parameters were optimised to achieve maximum sensitivity. The system was linear for the range of sulphur compound concentrations found in beer, and displayed good reproducibility. The calibrated SPME-GC-PFPD system was used to analyse several different varieties of beer from a range of breweries, and to investigate the change in the concentrations of sulphur compounds when beer is subjected to illumination.

The findings of this study show that packaging and labeling are not decisive for women’s final purchase-decision. Instead, they rely on recommendations from friends and family. The study further shows that sponsoring local beer events hosted by opinion leaders will have the most impact on women’s attitude to beer

This thesis aims to analyze the effects of franchise laws and excise tax breaks targeted specifically at small brewers, as well as the effects of the right of small brewers to self-distribute their products. The amount of the state excise tax per gallon, population density, and beer consumption per capita are also analyzed as secondary effects to explain the size and growth of the craft beer industry. The analysis is carried out using two-equation, multivariate ordinary least squares regressions at the national level and additional models for the Northeastern, Midwestern, Southern, and Western regions of the United States of America. The final discussions of this thesis discuss the findings of these legislations as well as the additional factors regressed and provide insight for implications or lack thereof on the booming American Craft Beer Industry.

This mystery is set in the early 1980s and based on actual events. A high-school student unearths dark and deadly secrets of his Appalachian community. The explosive consequences forever mark his own life, his family's, and his town's.
https://dc.etsu.edu/etsu_books/1009/thumbnail.jpg

Der Zellzyklus organisiert die Zellteilung, und kontrolliert die Replikation der DNA sowie die Weitergabe des Genoms an die nächste Zellgeneration. Er unterliegt einer strengen Kontrolle auf molekularer Ebene. Diese molekularen Kontrollmechanismen sind für das Überleben eines Organismus essentiell, da Fehler Krankheiten begüngstigen können. Vor allem Krebs ist assoziiert mit Abweichungen im Ablauf des Zellzyklus. Die Aufklärung solcher Kontrollmechanismen auf molekularer Ebene ermöglicht einerseits das Verständnis deren grundlegender Funktionsweise, andererseits können solche Erkenntnisse dazu beitragen, Methoden zu entwickeln um den Zellzyklus steuern zu können. Um die molekularen Abläufe des Zellzyklus in ihrer Gesamtheit besser zu verstehen, eignen sich computergestützte Analysen. Beim Zellzyklus handelt es sich um einen Signaltransduktionsweg. Die Eigenschaften dieser Prozesse stellen Rekonstruktion und Übersetzung in digital lesbare Formate vor besondere Herausforderungen in Bezug auf Skalierbarkeit, Simulierbarkeit und Parameterschätzung. Diese Studie präsentiert eine großskalige Netzwerkrekonstruktion des Zellzyklus des Modellorganismus Saccharomyces cerevisiae. Hierfür wurde die reaction-contingency Sprache benutzt, die sowohl eine mechanistisch detaillierte Rekonstruktion auf molekularer Ebene zulässt, als auch deren Übersetzung in ein bipartites Boolesches Modell. Für das Boolesche Modell mit 2506 Knoten konnte ein zyklischer Attraktor bestimmt werden, der das Verhalten einer sich teilenden Hefezelle darstellt. Das Boolesche Modell reproduziert zudem das erwartete phänotypische Verhalten bei Aktivierung von vier Zellzyklusinhibitoren, und in 32 von 37 getesteten Mutanten. Die Rekonstruktion des Zellzyklus der Hefe kann in Folgestudien genutzt werden, um Signaltransduktionswege zu integrieren, die mit dem Zellzyklus interferieren, deren Schnittstellen aufzuzeigen, und dem Ziel, die molekularen Mechanismen einer ganzen Zelle abzubilden, näher zu kommen. Diese Studie zeigt zudem, dass eine auf reaction- contingency Sprache basierte Rekonstruktion geeignet ist, um ein biologisches Netzwerk konsistent mit empirischer Daten darzustellen, und gleichzeitig durch Simulation die Funktionalität des Netzwerkes zu überprüfen.
The survival of a species depends on the correct transmission of an intact genome from one generation to the next. The cell cycle regulates this process and its correct execution is vital for survival of a species. The cell cycle underlies a strict control mechanism ensuring accurate cell cycle progression, as aberrations in cell cycle progression are often linked to serious defects and diseases such as cancer. Understanding this regulatory machinery of the cell cycle offers insights into how life functions on a molecular level and also provides for a better understanding of diseases and possible approaches to control them. Cell cycle control is furthermore a complex mechanism and studying it holistically provides for understanding its collective properties. Computational approaches facilitate holistic cell cycle control studies. However, the properties of the cell cycle control network challenge large-scale in silico studies with respect to scalability, model execution and parameter estimation. This thesis presents a mechanistically detailed and executable large-scale reconstruction of the Saccharomyces cerevisiae cell cycle control network based on reaction- contingency language. The reconstruction accounts for 229 proteins and consists of three individual cycles corresponding to the macroscopic events of DNA replication, spindle pole body duplication, and bud emergence and growth. The reconstruction translated into a bipartite Boolean model has, using an initial state determined with a priori knowledge, a cyclic attractor which reproduces the cyclic behavior of a wildtype yeast cell. The bipartite Boolean model has 2506 nodes and correctly responds to four cell cycle arrest chemicals. Furthermore, the bipartite Boolean model was used in a mutational study where 37 mutants were tested and 32 mutants found to reproduce known phenotypes. The reconstruction of the cell cycle control network of S. cerevisiae demonstrates the power of the reaction-contingency based approach, and paves the way for network extension with regard to the cell cycle machinery itself, and several signal transduction pathways interfering with the cell cycle.

This study explores the psychological dynamics associated with labor and birth in order to better understand the role these experiences play in women’s psychological development. This research study utilized interpretative phenomenological analysis as a research methodology and sought to address the following questions through the theoretical perspective of psychoanalysis and social constructionism: How does the experience of pregnancy and birth impact the subjectivity of women? How do women make sense of these experiences? What role does the body play in women’s psychological development? Does the experience of childbirth mark a unique developmental phase in the psychological life of women? In this research study, six women were asked to describe their birth narrative in full and respond to a series of open-ended questions. The results of this study indicate that pregnancy and childbirth is a porous developmental period associated with fears about capacity and feelings of omnipotence as well as multiple losses and a new sense of self. One of the more significant findings of this study is that the experience of labor and birth is felt by many women to involve feelings associated with encountering death. This finding may lead to increased understanding of why pregnancy and childbirth results in fragmentation for some women, while it appears to be a catalyst for increased subjectivity and maternal embodiment for other women.

Thesis: M.B.A., Massachusetts Institute of Technology, Sloan School of Management, 2015.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 100-103).
Some scholars argue that Japanese companies show excellence in developing operational effectiveness but rarely have strategies (e.g., Porter, 1996). One reason might be the persistent mindset (especially among large companies), formed during Japan's rapid growth period, which prioritized the pursuit of effective production and broad distribution of products to fully realize market growth, rather than adopting a distinct competitive strategy. Although the Japanese economy has been stagnant for more than two decades, the above-described mindset remains deeply embedded in the guise of "continuous improvement" or "customers are everything"- strategies that are still found across many Japanese industries. Another reason for the lack of strategies relates to the fact that, during the economic stagnation, an increasing number of companies have diversified their business portfolio in the search for new growth opportunities overseas. While globalization itself is a reasonable option even inevitable for some industries-implementing such a corporate strategy can lead some companies to vague business strategies. Moving into another industry can make management even more complicated (Markides, 1999), requiring that the strategy of each business must be given considerable attention when a firm embarks on globalization. This thesis explores Kirin's strategy for its Japanese beer business based on the factors described above. Although each player in the beer business worked hard to improve its product development and customer-facing skills in order to survive in a market that has been in decline for the past nearly twenty years, in the end every player competes fiercely for the same customers while offering similar products in the same fields. Ironically, this homogeneous effort maintains commoditization of the entire market over the long run. Product strategies or operational improvements are not enough to move away from this conundrum; Kirin needs a new business strategy, immediately. Therefore, the aim of this thesis is to explore what distinct strategic position(s) Kirin should adopt and what type of organizational system it should develop in the future. Through my analysis of Kirin using strategic frameworks and case studies, I found that Kirin has managed to survive the competition so far, cultivating many and varied capabilities in response to external changes. However, to deal with possible mid- and long-term changes in the beer market and the business model currently in place, Kirin has to review its strategic position and reform its organizational environment to focus on the development of new capabilities. Note: The views expressed in this thesis are solely my own and do not necessarily reflect the views of Kirin Holding Co. Ltd., my employer.
by Kan Yamamoto.
M.B.A.

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Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico - CNPQ
A delimita??o taxon?mica ao n?vel de esp?cie em plantas n?o ? uma tarefa f?cil, devido ao grande polimorfismo dos vegetais. No presente trabalho objetivamos avaliar tr?s morfotipos (formas) de Cryptanthus zonatus (Vis.) Beer (Bromeliaceae, Bromelioideae) descritos na literatura, lan?ando m?o da biologia floral e fenologia, al?m da morfologia floral e anatomia foliar. As ?reas de realiza??o do estudo foram o Parque Estadual das Dunas de Natal e a Reserva Particular do Patrim?nio Natural da Mata Estrela, no munic?pio de Ba?a Formosa Rio Grande do Norte (RN). Para o estudo fenol?gico foram feitas visitas mensais durante o per?odo de um ano, onde foram feitas observa??es acerca das fenofases de flora??o e frutifica??o das popula??es das tr?s formas de C. zonatus. Para biologia floral, procurou-se avaliar dados como: tipo de visitante floral, volume e concentra??o de n?ctar e hor?rio de abertura e fechamento das flores. Flores das tr?s formas foram coletadas em campo, analisadas ao estereomicrosc?pio e as medidas das pe?as foram feitas com a ajuda de um paqu?metro. Cortes transversais e paradermais de folhas das tr?s formas foram feitos, corados e posteriormente analisados ao microsc?pio ?tico. Observa??es de cortes paradermais em microsc?pio eletr?nico de varredura tamb?m foram feitas. Todos os dados mostraram n?o haver diferen?as significativas entre as tr?s formas. Desse modo, conclui-se que n?o h? subs?dios para o reconhecimento dos tr?s morfotipos de C. zonatus como entidades taxon?micas, e que as ferramentas de fenologia, anatomia, biologia floral e morfologia floral n?o foram conclusivas para delimitar esses tr?s morfotipos. Ainda visando caracterizar melhor a Flora de Bromeliaceae do RN, foi tamb?m estudada a anatomia foliar de Orthophytum disjunctum, uma esp?cie de um g?nero irm?o de Cryptanthus, apenas recentemente documentada no semi?rido do RN. A compara??o anat?mica entre Cryptanthus e Orthophytum permitiu a separa??o dos g?neros com base na disposi??o dos est?matos e maior espessura do par?nquima aqu?fero. Durante os trabalhos de campo, foi poss?vel, ainda, documentar a primeira ocorr?ncia de Aechmea muricata no RN, na RPPN Mata Estrela, auxiliando no entendimento da distribui??o do t?xon, que encontra-se amea?ado de extin??o.
The taxonomic delimitation at the species level in plants is not an easy task due to the large polymorphism of plants. In this project we aimed to evaluate three morphotypes (forms) of Cryptanthus zonatus (Vis.) Beer ( Bromeliaceae, Bromelioideae ) described in the literature using fl oral biology and phenology, as well as flo ral morphology and leaf anatomy . These studies were conducted in the Parque Estadual das Dunas de Natal, Rio Grande Norte (RN) and Private Reserve of Natural Patrimony Mata Estrela , in the municipality of Ba ? a Form osa. The survey of the phenology of the morphotypes involved monthly specimen observation in the field, during one year. In each visit, we observed the status of flowering and fruiting phenophases of the population of the three forms of C. zonatus . For flo ral biology we sought to evaluate data like: observed floral visitors, nectar volume and concentration, time of anthesis and closing of flowers . Flowers of the three fo rms were collected in the field , analyzed by stereomicroscope, and measurements of the f loral pieces were made with the help of a caliper . Transversal and paradermal sections of the leaves of the three forms were stained and then examined under an optical microscope. Observations of the epidermis under scanning electron microscopy were also conducted. The three m orphotypes could not be sepated based on all evidence investigated. Thus, we conclude that there is not evidences to support the recognition of C. zonatus morphotypes as taxonomic entities, and also that the tools of phenology, anatomy, biology and floral morphology were not useful to delimit these three forms . Yet to characterize better the Flora of Bromeli aceae of RN, the leaf anatomy of Orthophytum disjunctum was also studied. Orthophytum is the sister genus to Cryptanthus and only recently documented in the semiarid of RN. The anatomical comparison between Cryptanthus and Orthophytum allowed the separatio n of both genera based on the arrangement of stomata and thickness of aquiferous par?nquima . During the fieldwork, it was still possible to document the first occurrence of Aechmea muricata in RN, inside the Mata Estrela preserve, aiding the understanding of the distribution of the taxon that is currently threatened with extinction.

Doutoramento em Quimica
The work reported in this thesis aimed at applying the methodology known as metabonomics to the detailed study of a particular type of beer and its quality control, with basis on the use of multivariate analysis (MVA) to extract meaningful information from given analytical data sets. In Chapter 1, a detailed description of beer is given considering the brewing process, main characteristics and typical composition of beer, beer stability and the commonly used analytical techniques for beer analysis. The fundamentals of the analytical methods employed here, namely nuclear magnetic resonance (NMR) spectroscopy, gas-chromatography-mass spectrometry (GC-MS) and mid-infrared (MIR) spectroscopy, together with the description of the metabonomics methodology are described shortly in Chapter 2. In Chapter 3, the application of high resolution NMR to characterize the chemical composition of a lager beer is described. The 1H NMR spectrum obtained by direct analysis of beer show a high degree of complexity, confirming the great potential of NMR spectroscopy for the detection of a wide variety of families of compounds, in a single run. Spectral assignment was carried out by 2D NMR, resulting in the identification of about 40 compounds, including alcohols, amino acids, organic acids, nucleosides and sugars. In a second part of Chapter 3, the compositional variability of beer was assessed. For that purpose, metabonomics was applied to 1H NMR data (NMR/MVA) to evaluate beer variability between beers from the same brand (lager), produced nationally but differing in brewing site and date of production. Differences between brewing sites and/or dates were observed, reflecting compositional differences related to particular processing steps, including mashing, fermentation and maturation. Chapter 4 describes the quantification of organic acids in beer by NMR, using different quantitative methods: direct integration of NMR signals (vs. internal reference or vs. an external electronic reference, ERETIC method) and by quantitative statistical methods (using the partial least squares (PLS) regression) were developed and compared. PLS1 regression models were built using different quantitative methods as reference: capillary electrophoresis with direct and indirect detection and enzymatic essays. It was found that NMR integration results generally agree with those obtained by the best performance PLS models, although some overestimation for malic and pyruvic acids and an apparent underestimation for citric acid were observed. Finally, Chapter 5 describes metabonomic studies performed to better understand the forced aging (18 days, at 45 ºC) beer process. The aging process of lager beer was followed by i) NMR, ii) GC-MS, and iii) MIR spectroscopy. MVA methods of each analytical data set revealed clear separation between different aging days for both NMR and GC-MS data, enabling the identification of compounds closely related with the aging process: 5-hydroxymethylfurfural (5-HMF), organic acids, γ-amino butyric acid (GABA), proline and the ratio linear/branched dextrins (NMR domain) and 5-HMF, furfural, diethyl succinate and phenylacetaldehyde (known aging markers) and, for the first time, 2,3-dihydro-3,5-dihydroxy-6-methyl-4(H)-pyran-4-one xii (DDMP) and maltoxazine (by GC-MS domain). For MIR/MVA, no aging trend could be measured, the results reflecting the need of further experimental optimizations. Data correlation between NMR and GC-MS data was performed by outer product analysis (OPA) and statistical heterospectroscopy (SHY) methodologies, enabling the identification of further compounds (11 compounds, 5 of each are still unassigned) highly related with the aging process. Data correlation between sensory characteristics and NMR and GC-MS was also assessed through PLS1 regression models using the sensory response as reference. The results obtained showed good relationships between analytical data response and sensory response, particularly for the aromatic region of the NMR spectra and for GC-MS data (r > 0.89). However, the prediction power of all built PLS1 regression models was relatively low, possibly reflecting the low number of samples/tasters employed, an aspect to improve in future studies.
O trabalho apresentado nesta tese pretendeu aplicar a metodologia usualmente designada por metabonómica, baseada na utilização de métodos de análise multivariada (MVA) para extrair a informação relevante de conjuntos de dados, obtidos por técnicas analíticas, no estudo detalhado de um determinado tipo de cerveja e seu controlo de qualidade. No Capítulo 1, é apresentada uma descrição detalhada sobre cerveja: seu processo de fabrico, principais características e composição típica, estabilidade da cerveja e principais técnicas utilizadas para o estudo da composição da cerveja e do seu controlo de qualidade. Os fundamentos teóricos das técnicas analíticas utilizadas no decorrer da tese, nomeadamente espectroscopia de ressonância magnética nuclear (RMN), cromatografia em fase gasosa-espectrometria de massa (GC-MS) e espectroscopia de infravermelho-médio (MIR), conjuntamente com uma descrição da metodologia de metabonómica estão descritos no Capítulo 2. No Capítulo 3, está descrita a aplicação de RMN de alta resolução para caracterizar detalhadamente a composição química de um tipo de cerveja. O espectro de RMN de 1H obtido pela análise directa de cerveja apresenta uma elevada complexidade, confirmando a capacidade da espectroscopia de RMN para detecção de uma grande variedade de famílias de compostos, numa só corrida. Experiências de RMN bidimensionais foram realizadas para uma identificação detalhada espectral, tendo-se conseguido identificar cerca de 40 compostos, incluindo álcoois, aminoácidos, ácidos orgânicos, nucleósidos e açúcares. Numa segunda parte do Capítulo 3, a variabilidade composicional da cerveja foi estudada. Para tal, a metodologia de metabonómica foi aplicada aos dados de RMN de 1H (RMN/MVA) para avaliar a variabilidade existente entre cerveja da mesma marca, produzida no mesmo país mas diferindo nas instalações e datas de produção. Diferenças entre instalações e/ou datas de produção foram identificadas, revelando variações composicionais relacionadas com alguns passos do processo, tais como brassagem, fermentação e maturação. O Capítulo 4 descreve a quantificação de ácidos orgânicos em cerveja por métodos baseados na espectroscopia de RMN. Diferentes métodos quantitativos foram desenvolvidos e comparados, nomeadamente por integração directa dos sinais de RMN (vs. referência interna ou vs. uma referência externa electrónica, método ERETIC), e por métodos estatísticos quantitativos (usando a regressão parcial em mínimos quadrados (PLS)). Os modelos de PLS foram construídos usando como métodos quantitativos de referência a electroforese capilar com detecção directa e indirecta e ensaios enzimáticos. A comparação dos resultados obtidos pelos modelos de PLS1-RMN que demonstraram melhor poder de previsão com os resultados obtidos pelos métodos de integração directa foi realizada, estando estes últimos em concordância com os obtidos pelos modelos de PLS1, apesar de alguma sobreestimativa ter sido detectada na quantificação dos ácidos málico e pirúvico, assim como uma aparente subestimativa para o ácido cítrico. Finalmente, no Capitulo 5, desenvolveram-se estudos x metabonómicos para uma melhor compreensão do processo de envelhecimento forçado da cerveja. O processo de envelhecimento forçado (durante 18 dias, a 45 ºC) de um lote de cervejas foi acompanhado por i) RMN, ii) GC-MS e iii) MIR. Aplicando os métodos de MVA a cada um dos conjuntos de dados, observou-se uma clara separação entre dias de envelhecimento para os dados de RMN e de GC-MS, com a identificação de compostos significativamente relacionados com o processo de envelhecimento, nomeadamente 5-hidroximetilfurfural (5-HMF), ácidos orgânicos, ácido γ-amino butírico (GABA), prolina, e a razão de dextrinas lineares/ramificadas (por RMN) e 5-HMF, furfural, succinato de dietilo e fenilacetaldeído (marcadores do envelhecimento da cerveja) e, pela primeira vez, 2,3-dihidro-3,5-dihidroxi-6-metil-4(H)-piran-4-ona (DDMP) e maltoxazina (por GC-MS). Para os dados de MIR, nenhuma tendência de envelhecimento foi identificada nos moldes experimentais investigados. A correlação entre os dados de RMN e GC-MS foi também realizada através dos métodos estatísticos de análise do produto externo (OPA) e por correlação espectral interdomínios (statistical heterospectroscopy-SHY), permitindo a identificação de um maior número de compostos (11 compostos, 5 dos quais ainda não estão atribuídos) relacionados directamente com o envelhecimento, originando uma descrição mais completa das variações composicionais que ocorrem durante o processo de envelhecimento. A correlação entre dados sensoriais e os dados analíticos obtidos por RMN e GC-MS também foi avaliada, usando para tal, modelos de regressão de PLS tendo os dados sensoriais como referência, Os resultados obtidos demonstram uma relação entre os dados analíticos e os sensoriais, especialmente para a região aromática do espectro de RMN e para os dados obtidos por GC-MS (r > 0.89). Contudo, o poder de previsão de todos os modelos de PLS1 construídos foi relativamente baixo, reflectindo o reduzido número de amostras/provadores utilizados neste estudo.

The paper examines the behavior of the supply chain through a system dynamic model. The theoretical part presents system dynamics, the Beer game and the simulation environment in which the model was created. In the practical part, the response of five surveyed decision-making order rules on the 4 patterns of demand is analyzed.

This research paper tests for factors that correlate with brewery success, generates growth projections for distinct industry sectors, implements Porter’s "Five-Forces" framework, and establishes general considerations for opening a craft brewery. There were no significant findings when testing for factors that correlate with brewery success. This reveals that breweries can successfully operate in a diverse range of environments, and that success is highly attributable to entrepreneurial ability and other difficult-to-measure forces. Growth in volume production is projected to be positive for microbreweries, brewpubs, and regional breweries until at least 2015. Contract breweries will suffer negative growth. Porter's analysis reveals an industry described by low-to-moderate threat of entrants, moderate internal rivalry, low threat of substitute goods, moderate-to-high bargaining power of consumers, and moderate bargaining power of suppliers.

Thesis analyses usage of a potential of Czech republic in beer tourism via beer tours. The main aim was to create new tours, which would be connecting small familial breweries in separated areas of Czech republic, east, west, middle of the republic plus Prague. Thesis was logically separated into two parts, theoretical and practical. Theoretical part shoul provide basic information about tourism, services and marketing of the services, which includes situation analysis and marketing mix. The end of this part involves description of the situation of breweries in Czech republic, like number of breweries, statistics of production and consumption of beer; and situation of beer tourism in this land. Practical part is applying knowlendges of theoretical part. First chapter includes analysis of the beer tours market, competition, suppliers, element of distribution and potentional customer. Next chapter is whole about new beer tours, this chapter involves description and process of individual tours and the last chapter includes layout of marketing mix.

Birth of a Mother is a memoir that tells the story of how my unplanned pregnancy helps me to transform from a damaged adolescent into an empowered mother. Using a first person, present tense narrative, I relive the nine months leading up to the unmedicated home birth of my first child, exploring the conflicts I faced over my obesity, over having no job and no place to call home, and over developing a relationship with a man who was not the baby's father. Weaving in past tense vignettes, I attempt to show how I prepared myself for impending motherhood by reflecting on my mother's short, violent life and the abuse I suffered at her hands; the effect of losing my mother at the age of twelve and my quest to find someone to fill her role throughout my adolescence; my experiences with faith, from Christianity, to Buddhism, to Atheism, to Paganism; and by struggling to heal the emotional scars left over from suffering childhood abuse, and multiple rapes as a teenager. As I uncover parallels between my mother's life and my own, I come to a new understanding of the mental illness that seems prevalent in my family, of the causes and triggers of my personal flaws, and of methods that I can use to become for my child the mother I always wanted for myself.
ID: 030423067; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Thesis (M.F.A.)--University of Central Florida, 2011.; Includes bibliographical references (p. 158-161).
M.F.A.
Masters
English
Arts and Humanities
Creative Writing

To investigate the relationship between birth asphyxia and neurological impairment a cohort of 184 infants with a low (≤3) one-minute Apgar score was studied. All were singletons, apparently normally formed, and born at term (≥37 weeks' gestation) in the John Radcliffe Hospital, between January 1984 and September 1985. The 181 cohort survivors were traced at the age of five years; 159 were assessed by a paediatrician on a battery of neurodevelopmental tests, and information about a further eight was obtained from other sources. Three infants in the cohort died neonatally with a diagnosis of birth asphyxia, and three had spastic quadriplegia, profound developmental delay and visual impairment. Examination of the perinatal histories of these six children, including their fetal heart rate patterns in labour and acid-base status at delivery, found convincing evidence of birth asphyxia. Only one other child in the cohort exhibited similar signs of birth asphyxia; he was unimpaired at the age of five. To assess the impact of birth asphyxia on the overall rate of cerebral palsy, all cases of cerebral palsy born to Oxford residents in the study period were identified. Of 30 cases of cerebral palsy, the three identified in the follow-up study were the only ones whose impairment could be attributed to birth asphyxia in a full-term birth. Birth asphyxia therefore accounted for 10% of all cases of cerebral palsy, a fraction that agrees with previous estimates. The frequency of cerebral palsy due to birth asphyxia was estimated as 1 in 3800 full-term livebirths. A detailed analysis of the test scores of the 159 children assessed by the paediatrician failed to show any association between their acid-base values at delivery and test scores, or between their fetal heart rate patterns in labour and test scores. These results conform with the view that birth asphyxia has an "all or nothing" effect, and that it presents as a cluster of abnormal neonatal signs, including persistent cerebral depression, severe acidaemia, neonatal encephalopathy, and multiorgan dysfunction.

This thesis examines the birth of the Great Bear Rainforest, a large tract of temperate rainforest located on British Columbia’s central and north coasts. While the Great Bear Rainforest emerges through many intersecting forces, in this study I focus on the contributions of conservation science asking: how did conservation biology and related sciences help constitute a particular of place, a particular kind of forest, and a particular approach to biodiversity politics? In pursuit of these questions, I analyzed several scientific studies of this place completed in the 1990s and conducted interviews with people involved in the environmental politics of the Great Bear Rainforest. My research conclusions show that conservation science played an influential role in shaping the Great Bear Rainforest as a rare, endangered temperate rainforest in desperate need of protection, an identity that counters the entrenched industrial-state geographies found in British Columbia’s forests. With the help of science studies theorists like Bruno Latour and Donna Haraway, I argue that these conservation studies are based upon purification epistemologies, where nature - in this case, the temperate rainforest - is separated out as an entity to be explained on its own and ultimately ’saved’ through science. Further, I posit that the scientific practices surrounding the Great Bear Rainforest are steeped in what I call protected area fetishism, in that they tend to mistake protected areas as a fixed, objective ’thing-in-itself’ necessary for biodiversity conservation. The overemphasis on protected areas enacted by conservation science obfuscates past and present relations contributing to the on-going reduction of biodiversity loss on the coast of British Columbia and elsewhere.
Arts, Faculty of
Geography, Department of
Graduate

Market segmentation is one important Marketing technique addressed by companies in order to understand who are their potential clients in the market in general and afterwards develop an effective marketing campaign focused on those clients with the objective of increasing their sales, maximize their profits and in this way guarantee their sustainability and growth. This dissertation has the objective of helping NAU beer, a Portuguese start-up in the alcoholic beverages sector in Portugal. The main purpose is to understand on which segments should NAU focus its strategy. In order to address this objective, the Portuguese Market was analyzed and divided according to alcoholic drinks consumption habits, alcoholic drinks purchasing habits and characteristics most valued in alcoholic drinks. To do this analysis, two Focus Groups were conducted, as well as an Online Survey and afterwards a Cluster Analysis that ended up dividing the market into 5 segments. The results of this dissertation identify two potential segments for NAU beer. Additionally, analyses were conducted for all the 5 segments.
A segmentação de clientes é uma técnica de Marketing utilizada pelas empresas de forma a perceber quem são os seus potenciais clientes no mercado em geral e posteriormente preparar uma campanha de marketing eficiente focada nesses clientes com o objectivo de aumentar as suas vendas, maximizando o seu lucro e deste modo garantir a sua sustentabilidade e crescimento. Esta dissertação tem como objectivo ajudar a Cerveja NAU, uma start-up Portuguesa na indústria das bebidas alcoólicas em Portugal. O principal objectivo é perceber quem são os segmentos nos quais a NAU deve focar a sua estratégia. Para tal, foi analisado e segmentado o mercado Português relativamente a hábitos de consumo e compra das bebidas alcoólicas bem como principais características valorizadas nas bebidas alcoólicas. De forma a segmentar o mercado, foram realizados dois Focus Groups, um Questionário Online e posteriormente conduzida uma Análise de Clusters que acabou por dividir o mercado em 5 segmentos. Os resultados desta dissertação identificam dois potenciais segmentos para a Cerveja NAU. Adicionalmente, foram realizadas análises para todos os segmentos.