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Artículos de revistas sobre el tema "Vaccination – Immunologie"

Autor: Grafiati

Publicado: 1 de febrero de 2025

Última modificación: 31 de julio de 2025

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1

Confer, A. W., R. J. Panciera, M. J. Gentry, and R. W. Fulton. "Immunologie response to Pasteurella haemolytica and resistance against experimental bovine pneumonic pasteurellosis, induced by bacterins in oil adjuvants." American Journal of Veterinary Research 48, no. 2 (1987): 163–68. https://doi.org/10.2460/ajvr.1987.48.02.163.

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SUMMARY Immunogenicity of and protection afforded by Pasteurella haemolytica bacterins were studied in calves. Bacterins contained an aluminum hydroxide in gel (alh) adjuvant or one of the following oil-in-water adjuvants: Freund's complete adjuvant (fca), Freund's incomplete adjuvant (fia), and trehalose dimycolate (tdm). On days 0 and 7, calves were vaccinated with phosphate-buffered saline solution (pbss), a bacterin, or live P haemolytica. Transthoracic intrapulmonic challenge exposure was done on day 21. In 3 experiments, there were no significant (P > 0.05) differences between lung le

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2

Bazin, Hervé. "L’histoire des vaccinations. 2e partie : des vaccins pastoriens aux vaccins modernes." Bulletin de la Société Française d'Histoire de la Médecine et des Sciences Vétérinaires 13, no. 1 (2013): 45–63. https://doi.org/10.3406/bhsv.2013.1146.

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Cette présentation concerne la mise en route des vaccins à virulence atténuée par Pasteur et son équipe, donnant l’espoir d’obtenir un vaccin pour chaque maladie infectieuse. De nombreuses techniques ont été mises en oeuvre : vaccins chimiques, sérothérapie, séro-vaccination, vaccins tués (microbes) ou inactivés (virus), auto-vaccins, anatoxines, irradiation de parasites… pour les vaccins de première génération. La naissance de la biologie moléculaire et du génie génétique en microbiologie et en immunologie a conduit à une explosion de vaccins OGM dont les premiers exemples sont le vaccin hépa

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3

Olsen, S. C., and C. Johnson. "Immune Responses and Safety after Dart or Booster Vaccination of Bison with Brucella abortus Strain RB51." Clinical and Vaccine Immunology 19, no. 5 (2012): 642–48. http://dx.doi.org/10.1128/cvi.00033-12.

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ABSTRACTOne alternative for management of brucellosis in Yellowstone National Park bison (Bison bison) is vaccination of calves and yearlings. AlthoughBrucella abortusstrain RB51 vaccination protects bison against experimental challenge, the effect of booster vaccinations was unknown. This study characterized immunologic responses after dart or booster vaccination of bison withBrucella abortusstrain RB51. In two studies, 8- to 10-month-old female bison were inoculated with saline (n= 14), hand vaccinated with 1.1 × 1010to 2.0 × 1010CFU of RB51 (n= 21), or dart vaccinated with 1.8 × 1010CFU of

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4

Ridolfi, Irene, Luca Lo Sardo, Stefania Nicola, et al. "MAURIVAX: A Vaccination Campaign Project in a Hospital Environment for Patients Affected by Autoimmune Diseases and Adult Primary Immunodeficiencies." Vaccines 11, no. 10 (2023): 1579. http://dx.doi.org/10.3390/vaccines11101579.

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Background: Patients with autoimmune diseases (ADs) and primary immunodeficiencies (PIDs) are characterized by an increased risk of noninvasive and widespread infections as they are considered frail patients. In addition, many flares of the underlying disease are reported after routine vaccinations. To date, the vaccination rate in these two populations is suboptimal. According to the latest guidelines, targeted interventions are needed, such as strengthening the network of vaccination activities. Our project aimed to propose a pilot network for carrying out the recommended vaccinations in fra

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5

Rosenblat, Todd L., Mark G. Frattini, Suzanne M. Chanel, et al. "Phase II Trial of WT1 Analog Peptide Vaccine in Patients with Acute Myeloid Leukemia (AML) in Complete Remission (CR)." Blood 120, no. 21 (2012): 3624. http://dx.doi.org/10.1182/blood.v120.21.3624.3624.

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Abstract Abstract 3624 WT1 is a transcription factor which has been implicated in leukemogenesis and has been used as a marker of minimal residual disease (MRD). We previously demonstrated the feasibility of vaccinating AML patients in CR with a multivalent WT1 peptide vaccine and inducing immune responses. In an effort to further explore the safety and efficacy of this approach, we are conducting a Phase II study in which the vaccine is administered to AML patients in first CR and who completed all planned postremission chemotherapy. Eligible patients had WT1 transcript detectable by RT-PCR.

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6

Gates, Dana M., Steven A. Cohen, Kelly Orr, and Aisling R. Caffrey. "Pharmacist-Administered Influenza Vaccination in Children and Corresponding Regulations." Vaccines 10, no. 9 (2022): 1410. http://dx.doi.org/10.3390/vaccines10091410.

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In our retrospective cohort study, we evaluated trends in pharmacist-administered pediatric influenza vaccination rates in the United States and corresponding state-level pharmacist pediatric vaccination authorization models, including minimum age requirements, vaccination protocols, and/or prescription requirements. An administrative health claims database was used to capture influenza vaccinations in children less than 18 years old with 1 year of continuous enrollment and joinpoint regression was used to assess trends. Of the 3,937,376 pediatric influenza vaccinations identified over the stu

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7

Buckwalter, Matthew, and Pramod Srivastava. "Form of antigen dictates immunity: Irradiated cell vs. whole cell lysate vaccination (48.16)." Journal of Immunology 178, no. 1_Supplement (2007): S77. http://dx.doi.org/10.4049/jimmunol.178.supp.48.16.

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Abstract The context in which antigen is perceived by the immune system dictates the quality of the ensuing immune response, which can range from tolerance to lasting immunity. In the current report we investigated the effects of vaccinating mice with antigen in two separate contexts, namely: Irradiated cells, or whole cell lysates. Using the MethA tumor model we observed that although a single vaccination with irradiated MethA cells leads to immunity in BALB/c mice, vaccination with the same cell equivalents of whole cell lysate does not. These results were surprising in light of the substant

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8

Huppke, L., C. Gebhardt, L. Grümme, et al. "AB1326 DIFFERENCES IN ADVERSE EVENTS EXPERIENCED BY INDIVIDUALS WITH INFLAMMATORY RHEUMATIC DISEASES AND HEALTHY INDIVIDUALS AFTER SARS-CoV-2 VACCINATION." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1892.1–1892. http://dx.doi.org/10.1136/annrheumdis-2023-eular.497.

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BackgroundSince individuals with inflammatory rheumatic diseases (IRDs) were excluded from the SARS-CoV-2 vaccination trials (1), uncertainty on the tolerability of the vaccines in this population was high. This caused a lower willingness to be vaccinated compared to the general population. Gaining more information on vaccine reaction in this population is critical.ObjectivesThe aim of the study was to improve knowledge of the tolerability of SARS-CoV-2 vaccination in patients with IRD and to identify potential specific risks of this population by comparison with a healthy cohort.MethodsIRD pa

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9

Wu, Yufei, Huanjie Li, Yangyang Wang, et al. "Opinion Polls and Antibody Response Dynamics of Vaccination with COVID-19 Booster Vaccines." Vaccines 10, no. 5 (2022): 647. http://dx.doi.org/10.3390/vaccines10050647.

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As the third year of the global COVID-19 pandemic, vaccination remains the most effective tool against infections and symptomatic illness. Comprehension regarding immunity to SARS-CoV-2 is limited, and the durability of immune responses after vaccination is currently not clear. In this study, we randomly collected 395 questionnaires to analyze the current state of COVID-19 vaccination. At the same time, the serum of 16 individuals who had received two doses of the COVID-19 vaccine were collected at different times before and after the booster vaccination. We analyzed the dynamic changes of SAR

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10

Robinson, Stacie J., Michelle M. Barbieri, Samantha Murphy, et al. "Model recommendations meet management reality: implementation and evaluation of a network-informed vaccination effort for endangered Hawaiian monk seals." Proceedings of the Royal Society B: Biological Sciences 285, no. 1870 (2018): 20171899. http://dx.doi.org/10.1098/rspb.2017.1899.

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Where disease threatens endangered wildlife populations, substantial resources are required for management actions such as vaccination. While network models provide a promising tool for identifying key spreaders and prioritizing efforts to maximize efficiency, population-scale vaccination remains rare, providing few opportunities to evaluate performance of model-informed strategies under realistic scenarios. Because the endangered Hawaiian monk seal could be heavily impacted by disease threats such as morbillivirus, we implemented a prophylactic vaccination programme. We used contact networks

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11

Hanson, Lars Å., and Sven Arne Silfverdal. "Vaccination immunology." Scandinavian Journal of Infectious Diseases 40, no. 9 (2008): 696–701. http://dx.doi.org/10.1080/00365540802029573.

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12

Schmitt, Michael, Anita Schmitt, Markus T. Rojewski, et al. "RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses." Blood 111, no. 3 (2008): 1357–65. http://dx.doi.org/10.1182/blood-2007-07-099366.

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Abstract The receptor for hyaluronic acid–mediated motility (RHAMM) is an antigen eliciting both humoral and cellular immune responses in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and multiple myeloma (MM). We initiated a phase 1 clinical trial vaccinating 10 patients with R3 (ILSLELMKL), a highly immunogenic CD8+ T-cell epitope peptide derived from RHAMM. In 7 of 10 patients, we detected an increase of CD8+/HLA-A2/RHAMM R3 tetramer+/CD45RA+/CCR7−/CD27−/CD28− effector T cells in accordance with an increase of R3-specific CD8+ T cells in enzyme linked immunospo

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13

Perez, S. A., S. Bisias, N. L. Kallinteris, et al. "Results from the first phase I clinical study of the novel Ii-Key/HER2/neu(776–790) hybrid peptide vaccine in patients with prostate cancer." Journal of Clinical Oncology 27, no. 15_suppl (2009): 3011. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.3011.

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3011 Background: HER-2/neu(776–790) represents an immunogenic epitope from the HER-2/neu oncoprotein whose immunogenicity is highly potentiated upon linkage with the Ii-Key moiety (LRMK) from the MHC class II invariant chain. Herein, we present the results of the first phase I clinical trial of the Ii-Key/HER-2/neu(776–790) (AE37) vaccine in patients (pts) with prostate cancer. Methods: Androgen-dependent (AD) and androgen-independent (AI) pts with HER-2/neu+ (IHC: 1–3) prostate adenocarcinomas were eligible. Concomitant medication with bicatulamide and LHRH or docitaxel was allowed. All pts r

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14

Stoffel, Sandro Tiziano, Matthias Schwenkglenks, and Thomas Mutschler. "General Practitioners’ Awareness and Perception of Current Pneumococcal Vaccination for Adult Patients with Known Risk Factors in Switzerland: Evidence from a Survey." Vaccines 11, no. 6 (2023): 1101. http://dx.doi.org/10.3390/vaccines11061101.

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In Switzerland, the National Immunization Advisory Group (NITAG) has formulated recommendations for pneumococcal vaccination among adult risk patients. Little is known about general practitioners’ (GPs’) perception, knowledge, and implementation of these recommendations. Therefore, we investigated GPs’ awareness and drivers of and barriers to pneumococcal vaccination using a cross-sectional web-based survey of GPs. Of the 300 study participants, 81.3% were aware of the recommendations for vaccinating at-risk adult patients, but only 42.7% were aware of all risk groups. The recommendations were

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15

Maslak, P. G., T. Dao, S. Gupta, et al. "Pilot trial of a synthetic breakpoint peptide vaccine in patients with chronic myeloid leukemia (CML) and minimal disease." Journal of Clinical Oncology 24, no. 18_suppl (2006): 6514. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.6514.

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6514 Background: CML is characterized by a tumor-specific fusion oncoprotein, BCR-ABL. Peptides spanning the B3A2 breakpoint of BCR-ABL can elicit MHC restricted T cell responses and clinical responses. No such data have previously been reported for vaccines targeting B2A2. Methods: We initiated a clinical trial administering synthetic analog breakpoint specific peptide vaccines for either B3A2 or B2A2 breakpoints to CML patients with major or complete cytogenetic remission. Measurable minimal disease was determined by either quantitative polymerase chain reaction (RQ-PCR) or nested PCR for BC

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16

Jokhdar, Hani, Ray Borrow, Abdulrazaq Sultan, et al. "Immunologic Hyporesponsiveness to Serogroup C but Not Serogroup A following Repeated Meningococcal A/C Polysaccharide Vaccination in Saudi Arabia." Clinical Diagnostic Laboratory Immunology 11, no. 1 (2004): 83–88. http://dx.doi.org/10.1128/cdli.11.1.83-88.2004.

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ABSTRACT In Saudi Arabia, vaccination with the meningococcal A/C polysaccharide (MACP) vaccine is advised every 3 years. A clinical outcome study was performed to test the effect of repeat vaccination with the MACP vaccine on the immune responses among Saudi nationals who live in the Makkah and Jeddah areas. Subjects (n = 230) aged 10 to 29 years were selected: 113 subjects with two or more prior vaccinations with the MACP vaccine, 79 subjects with one prior vaccination with the MACP vaccine, and 38 subjects naïve to vaccination with the MACP vaccine. All subjects received the MACP vaccine in

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17

Keilholz, Ulrich, Anne Letsch, Antonia Busse, et al. "A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS." Blood 113, no. 26 (2009): 6541–48. http://dx.doi.org/10.1182/blood-2009-02-202598.

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Abstract This study investigated the immunogenicity of Wilms tumor gene product 1 (WT1)–peptide vaccination in WT1-expressing acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) patients without curative treatment option. Vaccination consisted of granulocyte-macrophage colony-stimulating factor subcutaneously days 1 to 4, and WT1.126-134 peptide and 1 mg keyhole limpet hemocyanin on day 3. The initial 9 patients received 4 vaccinations biweekly, then monthly, and the subsequent 10 patients received continual biweekly vaccination. Seventeen AML patients and 2 refractory anemia with

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18

Veronese, Nicola, Nancy Zambon, Marianna Noale, and Stefania Maggi. "Poverty and Influenza/Pneumococcus Vaccinations in Older People: Data from The Survey of Health, Ageing and Retirement in Europe (SHARE) Study." Vaccines 11, no. 9 (2023): 1422. http://dx.doi.org/10.3390/vaccines11091422.

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Vaccine acceptance seems to be lower in poor people. The determinants of the lower vaccine coverage in poor people are not established. Therefore, we aimed to explore the association between poverty and influenza/pneumococcus vaccinations and the factors potentially associated with vaccination’s coverage in poor people. The data of the Survey of Health, Ageing and Retirement in Europe (SHARE), an ongoing longitudinal, multi-disciplinary, and cross-national European study where used. Poverty was defined using information on income and household size. Among 47,370 participants initially included

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19

Miller, Mechelle, Michael Tracey, Meagan Simpson, and Cecilia Mikita. "Pearls and pitfalls: Adverse cutaneous reactions after COVID-19 vaccination." Allergy and Asthma Proceedings 43, no. 6 (2022): 555–58. http://dx.doi.org/10.2500/aap.2022.43.220058.

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Background: Rashes after coronavirus disease of 2019 (COVID-19) mRNA vaccinations occur with typical and atypical presentations. Objective: The goal of this article is to increase awareness and review the various diagnosis and management of cutaneous adverse reactions associated with COVID-19 vaccinations for allergy/immunology fellows, residents, general physicians, and general practitioners. Methods: Pertinent information was included from the patient's case. A review of the available literature using the works cited in the most up-to-date reviews was completed. Results: A case of a patient

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20

van der Burg, Sjoerd H. "Immunology: prophylactic vaccination." Papillomavirus Report 15, no. 3 (2004): 168–70. http://dx.doi.org/10.1179/095741904225004927.

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21

Beverley, P. C. L. "Immunology of vaccination." British Medical Bulletin 62, no. 1 (2002): 15–28. http://dx.doi.org/10.1093/bmb/62.1.15.

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Scognamiglio, Francesca, Maria Pia Fantini, Chiara Reno, et al. "Vaccinations and Healthy Ageing: How to Rise to the Challenge Following a Life-Course Vaccination Approach." Vaccines 10, no. 3 (2022): 375. http://dx.doi.org/10.3390/vaccines10030375.

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In the context of an ageing population, one of the major Public Health goals is to promote healthy ageing. To rise to this challenge, rethinking conventional prevention paradigms and implementing them with vaccination at all stages of life is necessary. Indeed, vaccinations are able to both prevent pathogen specific diseases and all their downstream effects and to increase overall immune system plasticity and resilience. Our aim is to discuss the obstacles and opportunities in pursuing a “life-course vaccination approach” and to highlight the role of vaccines in healthy ageing. In doing so, we

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Grochowska, Magdalena, Aleksandra Ratajczak, Gabriela Zdunek, Aleksander Adamiec, Paweł Waszkiewicz, and Wojciech Feleszko. "A Comparison of the Level of Acceptance and Hesitancy towards the Influenza Vaccine and the Forthcoming COVID-19 Vaccine in the Medical Community." Vaccines 9, no. 5 (2021): 475. http://dx.doi.org/10.3390/vaccines9050475.

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Despite research conducted worldwide, there is no treatment specifically targeting SARS-CoV-2 infection with efficacy proven by randomized controlled trials. A chance for a breakthrough is vaccinating most of the global population. Public opinion surveys on vaccine hesitancy prompted our team to investigate Polish healthcare workers’ (HCWs) attitudes towards the SARS-CoV-2 and influenza vaccinations. In-person and online surveys of HCWs: doctors, nurses, medical students, and other allied health professionals (n = 419) were conducted between 14 September 2020 and 5 November 2020. In our study,

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24

Limentani, S. A., M. Campone, T. Dorval, et al. "Evaluation of a recombinant HER2 vaccine: Induction of specific antibodies, T-cells and preliminary activity in metastatic breast cancer patients." Journal of Clinical Oncology 24, no. 18_suppl (2006): 631. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.631.

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631 Background: We designed a vaccine to induce T cells able to recognize epitopes from HER2 and to engender a polyclonal antibody reponse. Methods: The vaccine is a recombinant HER2 protein, including its extra and part of its intra-cellular domains (ECD/ICD), combined with a potent immunologic adjuvant. Cohorts of patients with Stage II/III breast cancer (BC) received 20, 100 or 500 μg in the adjuvant setting. Treatment comprised of six vaccinations over 14 weeks, for the 500-μg dose, recall injections were given on weeks 34 and 38. The trial was extended to include an alternative vaccinatio

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MYLONAKIS (Μ.Μ. ΜΥΛΩΝΑΚΗΣ), M. M., A. F. KOUTINAS (Α.Φ. ΚΟΥΤΙΝΑΣ), and K. G. PLEVRAKI (Κ.Γ. ΠΛΕΥΡΑΚΗ). "Current aspects on vaccines and immunization in the dog and cat. Part II. Vaccines and vaccinations in the cat and postvaccinal complications." Journal of the Hellenic Veterinary Medical Society 50, no. 2 (2018): 130. http://dx.doi.org/10.12681/jhvms.15706.

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The widespread use of vaccinations among the feline population has greatly contributed to the control of the most common infectious diseases, such as panleukopenia, upper respiratory viral diseases, leukemia virus infection, rabies, infectious peritonitis, chlamydiosis and Bordetella infection that threaten the health status or the life itself of the affected cats. Kittens having received colostrum can be vaccinated as soon as the 6th week of life, while the colostrum-deprived neonates two weeks earlier, provided that inactivated vaccines will be used. The induction of immunization and mainten

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Hartley, Christopher. "Immunologic Strategies for Herpes Vaccination." JAMA 283, no. 6 (2000): 746. http://dx.doi.org/10.1001/jama.283.6.741.

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Friedman, H. M. "Immunologic Strategies for Herpes Vaccination." JAMA: The Journal of the American Medical Association 283, no. 6 (2000): 746. http://dx.doi.org/10.1001/jama.283.6.746.

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Enciu, Bianca Georgiana, Daniela Pițigoi, Alina Zaharia, et al. "COVID-19 Vaccination in Romania and the Benefits of the National Electronic Registry of Vaccinations." Vaccines 11, no. 2 (2023): 370. http://dx.doi.org/10.3390/vaccines11020370.

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Background: Recording real-time data of vaccinations performed, vaccine stocks, and adverse events following immunization is a particularly useful activity in the effective development of any vaccination campaign or vaccination program, guiding the decisions of public health authorities. The aim of this paper is to present the benefits of the National Electronic Registry of Vaccinations in providing useful information for the optimization of healthcare vaccination policies, specifically related to COVID-19 vaccination. Methods: We performed a descriptive study using data available in the repor

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CASTAING, Cécile. "Vaccination et passeport immunologique." Revista de Derecho y Genoma Humano Extra 2022, Extra 2022 (2022): 103–22. http://dx.doi.org/10.14679/2004.

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Hofstetter, Amelia R., Nedzad Music, Ram P. Kamal, and Ian A. York. "Influenza-specific ex vivo immune responses in ferrets commensurate with number of vaccinations despite decreased protection for repeat vaccines." Journal of Immunology 204, no. 1_Supplement (2020): 245.15. http://dx.doi.org/10.4049/jimmunol.204.supp.245.15.

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Abstract There is controversy in the literature whether consecutive year influenza vaccinations lead to decreased vaccine efficacy. Evidence for this effect is strongest in the context of repeated H3N2 vaccinations. As recently reported (NPJ Vaccines 4:28 (2019)), we recreated this phenomenon in the ferret model of influenza. Ferrets exposed to consecutive year vaccinations had significantly increased weight loss, viral shedding and fever after A/Hong Kong/4801/2014 (HK4801) virus challenge than ferrets only exposed to the 2017–2018 vaccine. One possible explanation for this phenomenon is that

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Bennett, Brady W., Lawrence S. Phillips, and Julie A. Gazmararian. "The Association of Vaccination for Common Adult Infectious Diseases and Uptake of COVID-19 Vaccines among 5,006,851 Veterans, 20 December 2020–31 October 2021." Vaccines 12, no. 2 (2024): 145. http://dx.doi.org/10.3390/vaccines12020145.

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Disparities in vaccination coverage for coronavirus disease 2019 (COVID-19) in the United States (U.S.) are consistent barriers limiting our ability to control the spread of disease, particularly those by age and race/ethnicity. This study examines the association between previous vaccination for common adult infectious diseases and vaccination for SARS-CoV-2 among a cohort of veterans in the U.S. Sociodemographic and clinical data were utilized from three databases within the Veterans Health Administration included in the electronic health record. We examined the association of previous vacci

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Kudrna, David A., George W. Teresa, Jeanene M. Arnzen, K. Scott Beard, and Deborah Olson. "Immunologic memory responses induced in BALB/c mice by cross-linked outer membrane extracts of four Salmonella serotypes." American Journal of Veterinary Research 48, no. 8 (1987): 1199–205. https://doi.org/10.2460/ajvr.1987.48.08.1199.

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SUMMARY Outer membrane proteins (omp), extracted from Salmonella enteritidis, S anatum, S typhimurium, and S infantis, were cross-linked to form a large immunogen (4-omp-lipopolysaccharide [lps]). Vaccinations with 4-omp-lps dissolved in phosphate-buffered saline solution and 4-omp-lps emulsified with muramyl dipeptide were capable of eliciting specific and sustained primary IgM and IgG responses in BALB/c mice, as well as inducing immunologic memory for 130 days. In addition to 4-omp-lps-specific responses, substantial IgM and IgG responses specific for each live homologous organism were dete

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Grabenstein, John D. "Guillain-Barré Syndrome and Vaccination: Usually Unrelated." Hospital Pharmacy 35, no. 2 (2000): 199–207. http://dx.doi.org/10.1177/001857870003500214.

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With the rapid pace of immunologic research, it is more important than ever for readers to understand rational immunodiagnosis, immunoprophylaxis, and immunotherapy. This column is intended to help you carry out proper immunologic drug use in your practice.

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Gawryś, Ada, Tomasz Gołębiowski, Dorota Zielińska, et al. "Knowledge, Attitudes and Practices of Flu Vaccination in Hemodialysis Patients." Vaccines 9, no. 2 (2021): 77. http://dx.doi.org/10.3390/vaccines9020077.

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Background: Hemodialysis (HD) patients have an increased risk of morbidity and mortality due to infections. Despite the positive effect of vaccinations, the implementation of this method of prophylaxis is low. Objectives: This study aimed to explore the knowledge, attitudes and practices of flu vaccination among HD patients of two different dialysis centers. Methods: A total of 193 patients (mean age 63.6 years), who voluntarily agreed to participate in an anonymous survey related to influenza vaccination, were enrolled in this cross-sectional study. Results: A total of 45% of patients declare

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Rahman, Sharif Md Habibur, Md Rukunuzzaman, Rubaiyat Alam, and Khan Lamia Nahid. "Persistence of anti-HBs and immunologic memory in children immunized with hepatitis B vaccine." Bangabandhu Sheikh Mujib Medical University Journal 16, no. 2 (2023): 101–5. http://dx.doi.org/10.3329/bsmmuj.v16i2.67207.

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Background: We aimed to examine the persistence of anti-HBs in Bangladeshi children aged 5 and 10 years after primary vaccination, and this response to a booster dose. Methods: A total of 100 children were enrolled who were divided into two groups (A and B). Group A comprised of 50 children vaccinated 5 years ago, and group B had 50 children vaccinated 10 years ago. Hepatitis B surface antibody titer was measured, and a booster dose of the vaccine was administered to those who had anti-HBs less than 10 mlU/ml. Seventeen such children from group A and 27 from group B were vaccinated with a boos

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Costantino, Andrea, Marco Michelon, Daniele Noviello, et al. "Attitudes towards Vaccinations in a National Italian Cohort of Patients with Inflammatory Bowel Disease." Vaccines 11, no. 10 (2023): 1591. http://dx.doi.org/10.3390/vaccines11101591.

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Background: The vaccination status of patients with inflammatory bowel disease (IBD) should be investigated before starting any treatment, and patients should eventually be vaccinated against vaccine-preventable diseases (VPDs). Patients with IBD may have suboptimal vaccination rates. The aim of this study was to evaluate the vaccination coverage, attitude towards vaccinations, and determinants among an Italian cohort of patients with IBD. Methods: AMICI, the Italian IBD patients’ association, sent an anonymous web-based questionnaire in February 2021. Previous vaccination status and patients’

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Cassimos, Dimitrios C., Evgnosia Effraimidou, Snezana Medic, Theoharis Konstantinidis, Maria Theodoridou, and Helena C. Maltezou. "Vaccination Programs for Adults in Europe, 2019." Vaccines 8, no. 1 (2020): 34. http://dx.doi.org/10.3390/vaccines8010034.

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Background: While all European countries implement vaccination programs for children, there are gaps in terms of vaccination programs for adults. Methods: We studied the 2019 vaccination policies for adults in 42 European countries. Results: Vaccination programs for adults were in place in all countries. However, there were considerable differences between countries in terms of number of vaccinations, target populations and frame of implementation (recommended or mandatory vaccinations). In particular the following vaccination policies were in place: influenza (42 countries), tetanus (31), dip

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Murdaca, Giuseppe, Giovanni Noberasco, Alberto Battaglini, et al. "Systemic Sclerosis and Vaccinations: A Register-Based Cohort Study about Seasonal Influenza and Streptococcus pneumoniae Vaccination Rate and Uptake from Liguria Regional Center, Northwest Italy." Vaccines 8, no. 2 (2020): 204. http://dx.doi.org/10.3390/vaccines8020204.

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Systemic sclerosis (SSc) is the connective tissue disease with the highest mortality and patients with chronic inflammatory immune-mediated diseases are at high risk of acquiring infections as they are often treated with immunosuppressive or biological drugs. This study, conducted among the patients followed by our clinical immunology, part of the Internal Medicine Department in the Ospedale Policlinico San Martino, Genoa, northwest Italy, has set itself the primary objective of analyzing the vaccine uptake and the vaccination coverage against both seasonal influenza and S. pneumoniae in a coh

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Rosamilia, Francesca, Giovanni Noberasco, Dario Olobardi, et al. "Flu and Pneumococcal Vaccine Coverage in Scleroderma Patients Still Need to Be Prompted: A Systematic Review." Vaccines 9, no. 11 (2021): 1330. http://dx.doi.org/10.3390/vaccines9111330.

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Systemic sclerosis (scleroderma, SSc) is an autoimmune connective tissue disease characterized by excessive production of collagen and multiorgan involvement. Scleroderma patients are at increased risk of influenza complications and pneumonia; thus, vaccinations are recommended. This systematic review evaluated the influenza and pneumococcus vaccination coverage for SSc patients. We included all studies from Pubmed reporting on influenza and pneumococcal vaccination rate in Scleroderma patients up to May 2021. The 14 studies thus selected identified a suboptimal vaccination rate in autoimmune

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Gallagher, Megan C., Sarah Haessler, Elizabeth Pecoy-Whitcomb, and Jonathan Bayuk. "Monitored COVID-19 mRNA vaccine second doses for people with adverse reactions after the first dose." Allergy and Asthma Proceedings 43, no. 1 (2022): 37–39. http://dx.doi.org/10.2500/aap.2022.43.210100.

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Background: After Emergency Use Authorization of the coronavirus disease 2019 (COVID-19) vaccines, guidance was provided by the Centers for Disease Control and Prevention that persons with an immediate allergic reaction to a messenger RNA (mRNA) COVID-19 vaccine should be evaluated by an allergist/immunologist before receipt of the second dose. Methods: In vaccinating health-care personnel, we referred those with significant reactions to allergy/immunology specialists so that they could safely receive the second dose. Results: We found that many reactions after the first dose were nonallergic

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Gauld, Natalie, Samuel Martin, Owen Sinclair, Helen Petousis-Harris, Felicity Dumble, and Cameron C. Grant. "Influences on Pregnant Women’s and Health Care Professionals’ Behaviour Regarding Maternal Vaccinations: A Qualitative Interview Study." Vaccines 10, no. 1 (2022): 76. http://dx.doi.org/10.3390/vaccines10010076.

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The uptake of maternal influenza and pertussis vaccinations is often suboptimal. This study explores the factors influencing pregnant women’s and health care professionals’ (HCPs) behaviour regarding maternal vaccinations (MVs). Pregnant/recently pregnant women, midwives, pharmacists and general practice staff in Waikato, New Zealand, were interviewed. The analysis used the behaviour change wheel model. Interviews of 18 women and 35 HCPs revealed knowledge about MVs varied with knowledge deficiencies hindering the uptake, particularly for influenza vaccination. HCPs, especially midwives, were

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Luiten, Rosalie M., Esther W. M. Kueter, Wolter Mooi, et al. "Immunogenicity, Including Vitiligo, and Feasibility of Vaccination With AutologousGM-CSF–Transduced Tumor Cells in Metastatic Melanoma Patients." Journal of Clinical Oncology 23, no. 35 (2005): 8978–91. http://dx.doi.org/10.1200/jco.2005.01.6816.

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PurposeTo determine the feasibility, toxicity, and immunologic effects of vaccination with autologous tumor cells retrovirally transduced with the GM-CSF gene, we performed a phase I/II vaccination study in stage IV metastatic melanoma patients.Patients and MethodsSixty-four patients were randomly assigned to receive three vaccinations of high-dose or low-dose tumor cells at 3-week intervals. Tumor cell vaccine preparation succeeded for 56 patients (88%), but because of progressive disease, the well-tolerated vaccination was completed in only 28 patients. We analyzed the priming of T cells aga

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Malchrzak, Wojciech, Mateusz Babicki, Dagmara Pokorna-Kałwak, and Agnieszka Mastalerz-Migas. "The Influence of Introducing Free Vaccination against Streptococcus pneumoniae on the Uptake of Recommended Vaccination in Poland." Vaccines 11, no. 12 (2023): 1838. http://dx.doi.org/10.3390/vaccines11121838.

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Since 2017, pneumococcal vaccination has evolved from a recommended chargeable vaccination to a mandatory, and therefore free, vaccination for all children. While a 10-valent vaccine is commonly used, parents have the option to use a 13-valent vaccine for a fee. This study aimed to investigate whether and how the introduction of free pneumococcal vaccination affected the uptake of recommended vaccination and to assess the association of chargeable pneumococcal vaccination with recommended vaccination. Data from 1595 vaccination record cards kept by six primary care clinics in urban and rural a

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Kluczna, Agnieszka, Rafał Orzeł, Anna Bardowska, and Tomasz Dzierżanowski. "The Degree of Acceptance of Cocoon Strategy of Vaccination against Influenza and COVID-19 in Palliative Home Care Professionals and Caregivers." Vaccines 11, no. 7 (2023): 1235. http://dx.doi.org/10.3390/vaccines11071235.

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Palliative care patients are an immunocompromised population, so the cocooning strategy of vaccinating those around them is a suitable protective strategy against infections. This is especially significant for infectious diseases such as influenza and COVID-19, which pose a challenge to the healthcare system. In order to improve the patient’s quality of life, it is necessary to develop research-based, defined strategies. This questionnaire-based study was conducted to determine the level of knowledge about influenza and SARS-CoV-2 coronavirus vaccination among the factual caregivers and medica

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Yagi, Asami, Yutaka Ueda, Mamoru Kakuda, et al. "Cervical Cancer Protection in Japan: Where Are We?" Vaccines 9, no. 11 (2021): 1263. http://dx.doi.org/10.3390/vaccines9111263.

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In Japan, government subsidies for human papillomavirus (HPV) vaccination of girls aged 13–16 commenced in 2010. By early 2013, vaccination had become a widely accepted national immunization program. However, in June of 2013, the Ministry of Health, Labor, and Welfare (MHLW), the government’s lead agency, suspended its recommendation for vaccination in response to reports of adverse vaccine events. The rate of HPV vaccination quickly dropped from 70% to almost zero, where it has lingered for eight years. In 2020, a new 9-valent HPV vaccine was licensed in Japan. The momentum seemed to be build

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Veronese, Nicola, Giusy Vassallo, Maria Armata, et al. "Multidimensional Frailty and Vaccinations in Older People: A Cross-Sectional Study." Vaccines 10, no. 4 (2022): 555. http://dx.doi.org/10.3390/vaccines10040555.

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It is known that influenza, herpes zoster, pneumococcal and pertussis infections may increase morbidity and mortality in older people. Vaccinations against these pathogens are effective in older adults. Frailty seems to be an important determinant of vaccination rates, yet data supporting this association are still missing. Therefore, we aimed to investigate the prevalence of four recommended vaccinations (influenza, herpes zoster, pneumococcal and diphtheria-tetanus-pertussis) and the association with multidimensional frailty assessed using a self-reported comprehensive geriatric assessment t

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Kohrt, Holbrook E., Antonia Müller, Jeanette Baker, et al. "Donor immunization with WT1 peptide augments antileukemic activity after MHC-matched bone marrow transplantation." Blood 118, no. 19 (2011): 5319–29. http://dx.doi.org/10.1182/blood-2011-05-356238.

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Abstract The curative potential of MHC-matched allogeneic bone marrow transplantation (BMT) is in part because of immunologic graft-versus-tumor (GvT) reactions mediated by donor T cells that recognize host minor histocompatibility antigens. Immunization with leukemia-associated antigens, such as Wilms Tumor 1 (WT1) peptides, induces a T-cell population that is tumor antigen specific. We determined whether allogeneic BMT combined with immunotherapy using WT1 peptide vaccination of donors induced more potent antitumor activity than either therapy alone. WT1 peptide vaccinations of healthy donor

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Haque, Afrin, Chomel Mahbub, Biplob Hossain, et al. "Breakthrough Infection Influenced SARS-CoV-2 IgG Antibody Titer in a Group of Healthcare Providers." Journal of Immunology & Clinical Research 8, no. 1 (2025): 1–5. https://doi.org/10.47739/immunology.1051.

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Background: The phenomenon of breakthrough infection during the COVID-19 pandemic has raised concerns regarding the efficacy of the vaccinations and healthcare providers are exposed to instances on a regular basis for professional reasons, putting them at risk. This study was aimed to look into the SARS-CoV-2 IgG status among the healthcare providers, reported with breakthrough infections. Methods: The study involved 78 healthcare providers (e.g., doctors, nurses, Lab personnel, support staffs) from a tertiary care hospital in Dhaka city. Blood samples were collected from participants who had

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Bellanti, Joseph A. "Basic Immunologic Principles Underlying Vaccination Procedures." Pediatric Clinics of North America 37, no. 3 (1990): 513–30. http://dx.doi.org/10.1016/s0031-3955(16)36902-4.

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Shah, Javeed A., Cecilia S. Lindestam Arlehamn, David J. Horne, Alessandro Sette, and Thomas R. Hawn. "Nontuberculous Mycobacteria and Heterologous Immunity to Tuberculosis." Journal of Infectious Diseases 220, no. 7 (2019): 1091–98. http://dx.doi.org/10.1093/infdis/jiz285.

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AbstractDevelopment of an improved tuberculosis (TB) vaccine is a high worldwide public health priority. Bacillus Calmette-Guerin (BCG), the only licensed TB vaccine, provides variable efficacy against adult pulmonary TB, but why this protection varies is unclear. Humans are regularly exposed to non-tuberculous mycobacteria (NTM) that live in soil and water reservoirs and vary in different geographic regions around the world. Immunologic cross-reactivity may explain disparate outcomes of BCG vaccination and susceptibility to TB disease. Evidence supporting this hypothesis is increasing but cha

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