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Articles de revues sur le sujet "796.045 6":
1
Gallo, Linda L., Yan Tian, Zaven Orfalian et Gary Fiskum. « Amelioration of popolysaccharide-induced sepsis in rats by free and esterified carnitine ». Mediators of Inflammation 2, no 7 (1993) : S51—S56. http://dx.doi.org/10.1155/s0962935193000766.
Résumé :
The purpose of this study was to determine if free or esterified carnitine could alter fatty acid metabolism and ameliorate sepsis in lipopolysaccharide (LPS)-treated rats. Throughout a 96 h observation post-LPS, i.p. administration of both markedly reduced illness and accelerated recovery. Carnitine prevented the acute LPS-induced rise in serum triglycerides (45 ± 6, 59 ± 5 vs. 83 ± 8 mg/ml, p < 0.001), respectively. This difference was accompanied by a significant increase in liver lipogenesis in LPS controls compared to both carnitines and normal rats (6.1 ± 0.3 vs. 3.9 ± 0.5, 4.3 ± 0.5, and 1.8 ± 0.4 μmol/h, respectively, p < 0.04). Compared to normal rats, total liver carnitine was significantly elevated in LPS controls and even higher in the carnitine groups (357 ± 40 vs. 736 ± 38, 796 ± 79, and 1081 ± 21 nmol/g). The data suggest that carnitines may be of therapeutic value in sepsis treatment and one action may be to partition fatty acids from esterification to oxidation.
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Bowmaker, Graham A., Effendy, John D. Kildea, Eban N. de Silva et Allan H. White. « Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXI Synthesis, Spectroscopy and Structural Systematics of Some 1 : 2 Binuclear Adducts of Silver(I) Compounds with Triphenylarsine, [(Ph3As)2Ag(µ-X)2Ag(AsPh3)2], X = Cl, Br, I, SCN ». Australian Journal of Chemistry 50, no 6 (1997) : 627. http://dx.doi.org/10.1071/c96037.
Résumé :
The syntheses and room-temperature single-crystal X-ray structural characterization of binuclear 1 : 2 adducts formed between silver(I) (pseudo-)halides, AgX, and triphenylarsine, AsPh3, for X = Cl, Br, I, SCN (1)–(4), are described. The chloride (1), obtained from 2-methylpyridine, is triclinic, P-1, a 10·410(2), b 12·716(2), c 14·196(6) Å, α 113·38(2), β 109·41(2), γ 75·08(1)°, Z = 1 (dimer); conventional R on F was 0·037 for No 3979 independent ‘observed’ (I > 3σ(I)) reflections. The bromide (2a), obtained from 2,6-dimethylpyridine, and iodide (3), obtained from a mixture of AgI/saturated KI in MeOH solutions, are isomorphous, monoclinic, P 21/c a≈ 24·2, b ≈ 13·9, c ≈ 20·2 Å, β ≈ 109·5°, Z = 4 dimers; R was 0·046 and 0·044 for No 5670 and 6039 respectively. The thiocyanate (4) has a similar cell, a 24·12(1), b 12·558(8), c 23·244(4) Å, β 110·11(3)°, Z = 4 dimers, R being 0·044 for No 7956; one of the thiocyanate ligands (which bridge in Ag-SCN-Ag mode) is disordered. A second polymorph of the bromide (2b) (from a mixture of AgBr/saturated KBr in H2O) is also monoclinic, P 21/c, a 14·121(8), b 25·577(3), c 21·968(2) Å, β 125·54(3)°, Z = 4 dimers (R was 0·047 for No 5715). Ag–As range between 2·568(1) and 2·633(1) Å throughout the series; in the isomorphous bromide and iodide, values increase slightly: 2·578(1)–2·611(1), cf. 2·601(2)-2·633(1) Å respectively. Ag–X are 2·568(2)-2·670(2) (Cl); 2·688(2)–2·715(2) (Br); 2·828(2)–2·856(1) Å (I); Ag-S, N for the ordered SCN group are 2·646(3), 2·255(6) Å. A redetermination of improved precision (R 0·035, No 6030) is reported for the triphenylphosphine/thiocyanate analogue. The far-infrared spectra of [(Ph3As)2Ag(µ-X)2Ag (AsPh3)2] show v(AgX) bands at 185, 145 (X = Cl), 145, 130, 106 (X = Br) and 121 cm-1 (X = I). The splittings and band widths reflect a decrease in the degree of distortion of the Ag(µ-X)2Ag units from a symmetrically bridged structure from X = Cl to I.
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Alexeeff, Stacey E., Kamala Deosaransingh, Stephen Van Den Eeden, Joel Schwartz, Noelle S. Liao et Stephen Sidney. « Association of Long-term Exposure to Particulate Air Pollution With Cardiovascular Events in California ». JAMA Network Open 6, no 2 (24 février 2023) : e230561. http://dx.doi.org/10.1001/jamanetworkopen.2023.0561.
Résumé :
ImportanceLong-term exposure to fine particulate air pollution (PM2.5) is a known risk factor for cardiovascular events, but controversy remains as to whether the current National Ambient Air Quality Standard (12 μg/m3 for 1-year mean PM2.5) is sufficiently protective.ObjectiveTo evaluate the associations between long-term fine particulate air pollution and cardiovascular events using electronic health record and geocoded address data.Design, Setting, and ParticipantsThis retrospective cohort study included adults in the Kaiser Permanente Northern California integrated health care system during 2007 to 2016 and followed for up to 10 years. Study participants had no prior stroke or acute myocardial infarction (AMI), and lived in Northern California for at least 1 year. Analyses were conducted January 2020 to December 2022.ExposureLong-term exposure to PM2.5. Individual-level time-varying 1-year mean PM2.5 exposures for every study participant were updated monthly from baseline through the end of follow-up, accounting for address changes.Main Outcomes and MeasuresIncident AMI, ischemic heart disease (IHD) mortality, and cardiovascular disease (CVD) mortality. Cox proportional hazards models were fit with age as time scale, adjusted for sex, race and ethnicity, socioeconomic status, smoking, body mass index, baseline comorbidities, and baseline medication use. Associations below the current regulation limit were also examined.ResultsThe study cohort included 3.7 million adults (mean [SD] age: 41.1 [17.2] years; 1 992 058 [52.5%] female, 20 205 [0.5%] American Indian or Alaskan Native, 714 043 [18.8%] Asian, 287 980 [7.6%] Black, 696 796 [18.4%] Hispanic, 174 261 [4.6%] multiracial, 1 904 793 [50.2%] White). There was a 12% (95% CI, 7%-18%) increased risk of incident AMI, a 21% (95% CI, 13%-30%) increased risk of IHD mortality, and an 8% (95% CI, 3%-13%) increased risk of CVD mortality associated with a 10 μg/m3 increase in 1-year mean PM2.5. PM2.5 exposure at moderate concentrations (10.0 to 11.9 μg/m3) was associated with increased risks of incident AMI (6% [95% CI, 3%-10%]) and IHD mortality (7% [95% CI, 2%-12%]) compared with low concentrations (less than 8 μg/m3).Conclusions and RelevanceIn this study, long-term PM2.5 exposure at moderate concentrations was associated with increased risks of incident AMI, IHD mortality, and CVD mortality. This study’s findings add to the evidence that the current regulatory standard is not sufficiently protective.
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Lang, Jillian M., Brittany Rebits, Steven E. Newman et Ned Tisserat. « Monitoring Mortality of Pythium Zoospores in Chlorinated Water Using Oxidation Reduction Potential ». Plant Health Progress 9, no 1 (janvier 2008) : 9. http://dx.doi.org/10.1094/php-2008-0922-01-rs.
Résumé :
Pythium species are frequently recovered from recycled irrigation water in greenhouse production systems and may cause damping off and root rot if the water is not disinfested properly. Chlorination is often employed as a disinfesting agent, but can be difficult to monitor accurately because its activity is pH-dependent. Oxidation reduction potential (ORP) is a reliable, real-time measurement of the oxidizing potential of a chlorine solution. We exposed zoospores of Pythium aphanidermatum and P. dissotocum municipal water where the ORP was increased by adding 0.125, 0.5, and 2 mg/liter chlorine (pH 7.6 to 8.1) or to the same water source where the pH was lowered to 6.0 prior to the addition of chlorine, resulting in a final pH of 6 to 7.3. Some zoospores of P. aphanidermatum and P. dissotocum survived treatment to the highest chlorine concentration for 4 min in water where pH was not lowered. When the water pH was lowered to 6.0 prior to chlorine addition, 100% of the P. aphanidermatum zoospores were killed after 0.5 min exposure to 0.5 mg/liter chlorine, where ORP ranged from 748 to 790 mV and pH 6.3. Lowering the initial water pH improved disinfestation of P. dissotocum zoospores at the highest chlorine concentration tested and a mean ORP of 790 mV. Accepted for publication 7 July 2008. Published 22 September 2008.
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Ellis, M., A. J. Webb, P. J. Avery et I. Brown. « The influence of terminal sire genotype, sex, slaughter weight, feeding regime and slaughter-house on growth performance and carcass and meat quality in pigs and on the organoleptic properties of fresh pork ». Animal Science 62, no 3 (juin 1996) : 521–30. http://dx.doi.org/10.1017/s135772980001506x.
Résumé :
AbstractA total of 897 pigs were used in a study to investigate the relative effects of terminal sire genotype (lines Av.Bv. C), sex (castrate v. gilt), slaughter weight (80 v. 100 v. 220 kg), feeding regimen (ad libitum v. restricted, 0·82 ad libitum intake) and slaughter-house (HI v. H2 v. H3) on growth performance, carcass and meat quality characteristics and the eating quality offresh pig meat. Sire line A was a pure Duroc population, and B and C were European-type experimental lines where C contained Pietrain and B did not. In total, 26 sires from line A, 42 sires from line B, and 21 sires from line C were mated to females from the same crossbred dam line and progeny were reared under standard conditions to slaughter. Following slaughter and carcass evaluation, samples of longissimus dorsi were investigated for a range of meat quality and organoleptic characteristics. Line A produced fatter carcasses (C fat depths = 15·6 v. 24·0 v. 14·0 mm for lines A, B, and C, respectively, average s.e. 0·39) with higher killing-out proportions (g/kg) (790 v. 779 v. 786 respectively, average s.e. 1·4) and higher visible marbling, less tissue separation, firmer backfat, and juicier (3·81 v. 3·67 v. 3·72 respectively, average s.e. 0·044: on a scale 1 (extremely dry) to 8 (extremely juicy)) and more acceptable meat (4·54 v. 4·37 v. 4·42 respectively average s.e. 0·037: on a scale 1 (dislike extremely) to 8 (like extremely)) with a lower shear force (5·35 v. 5·78 v. 5·67 kg respectively, average s.e. 0·078) than lines B and C which were similar in most respects. Increases in slaughter weight were associated with a reduction in growth rate (785 v. 769 v. 725 glday for 80, 100 and 120 kg slaughter weight respectively, average s.e. 8·5), increases in backfat (Cfat = 13·3 v. 24·2 v. 26·3 mm respectively, average s.e. 0·34) and longissimus muscle area (34·6 v. 40·7 v. 44·6 cm2 respectively, average s.e. 0·59) and a deterioration in tenderness (4·72 v. 4·40 v. 3·95 respectively, average s.e. 0·062: on a scale 1 (extremely tough) to 8 (extremely tender) and overall acceptability (4·65 v. 4·44 v. 4·25 respectively, average s.e. 0·045) and an increase in shear force (5·37 v. 5·58 v. 5·87 kg respectively, average s.e. 0·085). Slaughter-house had a significant impact on pork odour scores but not on other organoleptic properties. Pigs reared under ad libitum feeding grew faster (840 v. 678 g/day respectively, average s.e. 3·7), were fatter (Cfat = 15·8 v. 23·2 mm respectively, s.e. 0·28), had lower carcass yields (780 v. 790 g/kg respectively, average s.e. 1) and produced more tender, juicier meat than those reared under restricted feeding. Differences between castrated males and gilts in growth and carcass trait were in line with other studies and there were no significant differences between the sexes for eating quality. There were relatively few significant interactions (P < 0·05) for eating quality traits and most of these involved slaughter-house and were for pork odour intensity, which are of limited practical significance. This suggests that the effects of sire genotype, slaughter weight and feeding regimen on eating quality identified in this study are likely to be additive.
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Yaidee, Akawit, Chantana Punlek et Somchai Maneewan. « Experiment study investigation compare temperature series circuit and the parallel circuit of thermoelectric and variable water, electrical of thermoelectric for heat exchanger ». International Journal of Power Electronics and Drive Systems (IJPEDS) 10, no 2 (1 juin 2019) : 785. http://dx.doi.org/10.11591/ijpeds.v10.i2.pp785-791.
Résumé :
This paper presents the comparison temperature of thermoelectric <em>(</em>Tec1<em>-</em>12708<em>) </em>between the series circuit and parallel circuit by adjusting of water flow rate pump and electrical supplying to thermoelectric, The electrical voltage at 8,10 and 12 V,<em> </em>water flow rate in reservoir was 0<em>.</em>015 kg<em>/</em>s and 0<em>.</em>025 kg<em>/</em>s<em>. </em>Experiments perform were 6 hours<em>. </em>The result from the researches, thermoelectric with parallel circuit high temperature more than thermoelectric with series circuit<em>. </em>The parallel circuit of thermoelectric can work better than the series circuit in hot side<em>. </em>The different temperature hot side of parallel circuit with the electrical voltage at 8, 10 and 12 V water flow rate in reservoir was 0<em>.</em>015 kg<em>/</em>s temperature average is 22<em>.</em>44 <sup>o</sup>C, 22<em>.</em>90 <sup>o</sup>C, 29<em>.</em>86<em> </em><sup>o</sup>C, and water flow rate in reservoir was 0<em>.</em>025 kg<em>/</em>s temperature average is 20<em>.</em>67 <sup>o</sup>C, 26<em>.</em>66 <sup>o</sup>C, 27.69 <sup>o</sup>C<em>. </em>Thermoelectric with parallel circuit makes the higher temperature more than thermoelectric with series circuit about 33<em>%</em>, 37<em>%</em>, 44<em>% </em>water flow rate in reservoir was 0<em>.</em>015 kg<em>/</em>s and 30<em>%</em>, 40<em>%</em>, 41<em>% </em>water flow rate in reservoir was 0<em>.</em>025 kg<em>/</em>s.
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Ibrahim, Mustafa M., Marwa M. Attia, Hanadi B. Baghdadi et Mohamed Abdelsalam. « First report of Kudoa species (Myxozoa, Multivalvulida) infection in purple-spotted Bigeye (Priacanthus tayenus) from the Saudi Arabian Gulf ». PLOS ONE 19, no 1 (10 janvier 2024) : e0295668. http://dx.doi.org/10.1371/journal.pone.0295668.
Résumé :
The purple-spotted bigeye, Priacanthus tayenus, is a marine benthic fish native to the Indian and Pacific Oceans, including the Arabian Gulf in Saudi Arabia. This study identified a myxozoan parasite infecting wild P. tayenus from the Saudi Arabian Gulf. These parasites produced spherical to ovoid-shaped, white plasmodia enclosed within pseudocysts in the fish musculature. The annual infection rate was 5.1%, with the highest prevalence in summer (7.6%), followed by spring (6%), and autumn (2.5%), while no infections were observed in winter. The number of plasmodia per fish ranged from 100 to 150 (135.1 ± 16.2). Their dimensions were 4–4.7 mm (4.3 ± 0.3 mm) in length and 4.5–7 mm (6 ± 1.1 mm) in width. Milky-colored exudates within the plasmodia contained mature spores measuring 8–9 μm (8.6 ± 0.4 μm) x 6–7.5 μm (6.9 ± 0.5 μm). The polar capsules of the spores exhibited dimensions of 2–5 μm (3.5 ± 0.5 μm) x 2.5–4.5 μm (3 ± 0.45 μm). Both morphological and genetic analyses confirmed these plasmodia as a novel Kudoa species. Histopathological examination revealed atrophy in the surrounding muscles without an inflammatory response. This study documents the first occurrence of a novel Kudoa sp. in P. tayenus at the Jubail landing site in Saudi Arabia, emphasizing the need for further surveillance and investigations to elucidate its pathogenesis and implications for wild fish stocks.
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Inglis, Matthew. « Review of APOS Theory : A Framework for Research and Curriculum Development in Mathematics Education, Arnon et al. (2014). New York, NY, USA : Springer-Verlag New York. eBook ISBN : 978-1-4614-7966-6, Hardcover ISBN : 978-1-4614-7965-9 ». International Journal of Research in Undergraduate Mathematics Education 1, no 3 (octobre 2015) : 413–17. http://dx.doi.org/10.1007/s40753-015-0015-9.
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Murakami, Takashi, et Kunio Matsuzaki. « Friction and Wear Properties of Fe7Mo6-Based Alloy under Various Sliding Conditions ». Materials Science Forum 706-709 (janvier 2012) : 1083–88. http://dx.doi.org/10.4028/www.scientific.net/msf.706-709.1083.
Résumé :
In this study, the friction and wear properties of the Fe7Mo6-based alloy/Al2O3 tribopair were investigated at high temperatures in air and at 298 K in water. The Fe7Mo6-based alloy/Al2O3 tribopair exhibited friction coefficients as low as 0.5 at 298 K and 873 K in air. On the other hand, this tribopair exhibited higher friction coefficients at 573 K than at 298 K and 873 K. It was also found that the friction coefficients of this tribopair were approximately 0.5 in water. The Fe7Mo6-based alloy disk specimens and their paired Al2O3 ball specimens exhibited the highest specific wear rates at 873 K in air. Oxygen-rich phase was observed on the worn surfaces of all the disk specimens. Concerning the friction and wear tests at high temperatures in air, the amount of the oxygen-rich phase increased with increasing the testing temperature. In addition, a little larger amount of the oxygen-rich phase was observed on the worn surface formed at 298 K in water than that formed at 298 K in air.
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Bowmaker, Graham A., Peter C. Junk, Aaron M. Lee, Brian W. Skelton et Allan H. White. « Synthetic, Structural and Vibrational Spectroscopic Studies in Bismuth(III) Halide/N,N′-Aromatic Bidentate Base Systems. I Large-Cation (2,2′-Bipyridinium and 1,10-Phenan- throlinium) Salts of Polyhalobismuthate(III) Ions ». Australian Journal of Chemistry 51, no 4 (1998) : 293. http://dx.doi.org/10.1071/c97036.
Résumé :
Syntheses and room-temperature single-crystal X-ray studies are recorded for a variety of salts of cations derived from protonated 2,2′-bipyridine and 1,10-phenanthroline (bpyH+ and phenH+) with polyhalobismuthate(III) anions. ‘[(phenH)(phenH2)(H2O)2] [BiCl6]’ is triclinic, P-1, a 9·791(1), b 9·338(3), c 8·311(3) Å, α 73·46(3), β 69·71(2), γ 86·36(2)°, Z = 1; conventional R on |F| was 0·027 for No 4852 independent ‘observed’ (I > 3σ(I)) reflections. [BiCl6]3- is closely octahedral, accompanied by an interesting protonation/hydrogen-bonding array among the other moieties. The latter comment applies also to ‘[(phenH2)(H2O)][BiCl5](∞|∞)’, monoclinic, P2/c, a 8·388(1), b 12·004(1), c 17·146(3) Å, β 98·26(1)°, Z = 4, R 0·047 for No 2670, the anion array being a one-dimensional polymer with bridging chlorine atoms occupying cis sites in the pseudo-octahedral coordination sphere of the bismuth. [bpyH2]4 [Bi4Cl20] is monoclinic, P21/c, a 14·228(4), b 14·217(2), c 16·254(4) Å, β 110·14(2)°, Z = 2, R 0·045 for No 2777; in the novel centrosymmetric tetramer, the four bismuth atoms are bridged into a square array by four linearly coordinated halogen atoms at the centres of the edges, a pair of these lying cis in the pseudo-octahedral coordination sphere of each bismuth. [bpyH]3 [Bi2Cl9] is triclinic, P-1 a 19·288(7), b 14·251(3), c 7·644(3) Å, α 75·02(2), β 80·15(3), γ 72·76(2)°, Z = 2, R 0·072 for No 3600, the two pseudo-octahedrally coordinated bismuth atoms being bridged by three chlorine atoms on a mutual octahedral face, [Cl3Bi(µ-Cl)3BiCl3]3-. [phenH] [BiCl4](∞|∞),H2O is triclinic, space group P-1, a 12·119(7), b 10·169(6), c 7·247(4) Å, α 69·30(4), β 75·05(4), γ 77·92(5)°, Z = 2, R 0·035 for No 2348. The anion is a one-dimensional polymer, successive metal atoms being bridged by pairs of chlorine atoms lying cis in the pseudo-octahedral coordination sphere. [bpyH]4 [Bi2I10] is monoclinic, P21/n, a 13·426(4), b 14·396(6), c 14·539(5) Å, β 101·31(3)°, Z = 2, R 0·11 for No 1862; the anion is of the form [I4Bi(µ-I)2BiI4]4- with quasi-octahedral bismuth. [bpyH] [BiI4](∞|∞) is monoclinic, C2/c, a 12·442(5), b 18·41(2), c 7·714(2) Å, β 92·80(3)°, Z = 4, R 0·080 for No 850, with a polymeric one-dimensional anion comparable to that in [phenH] [BiCl4](∞|∞),H2O. The structure of the 2,6-dimethylpyridinium salt of [BiCl6]3- is also recorded, as its acetonitrile solvate; triclinic, P-1, a 15·025(2), b 10·357(3), c 9·964(1) Å, α 83·14(2), β 89·32(1), γ 86·61(2)°, Z = 2, R 0·046 for No 3601; there is also an isomorphous bromide, and also an isostoichiometric bromide modelled as monoclinic, Cm, a 18·128(6), b 10·348(2), c 10·241(2) Å, β 121·31(3)°, Z = 2, R 0·050 for No 1379. Bands in the far-infrared and Raman spectra due to the v(BiCl) modes are assigned in [(phenH)(phenH2)(H2O)2] [BiCl6] and [bpyH2]4 [Bi4Cl20], and are discussed in relation to the structures of the complexes.
Thèses sur le sujet "796.045 6":
1
Peres, Paulo Roberto Monteiro. « A perspectiva do esporte como elemento responsável pelo afastamento de crianças e adolescentes das drogas e da criminalidade na cidade do Rio de Janeiro ». Doctoral thesis, 2014. http://hdl.handle.net/10348/3294.
Résumé :
Tese de Doutoramento em Ciências do DesportoO tema deste estudo incide sobre a perspectiva criada em torno do esporte, no sentido de afastar crianças e adolescentes das drogas e da criminalidade na cidade do Rio de Janeiro, onde projetos patrocinados por instituições públicas ou privadas, localizadas em favelas e sem pagamento por parte dos frequentadores, congregam milhares de pessoas de várias idades, particularmente crianças e adolescentes, para atividades esportivas e não esportivas. A metodologia do estudo incidiu no recolhimento e análise de informações via pesquisa de campo, onde foi aplicado um questionário semiaberto a meninos de 7 a 17 anos, vinculados a instituições públicas ou privadas que oferecem atividades relacionadas a esportes, artes, música e religião, destacando os aspectos qualitativos da investigação, onde a confrontação de resultados em dois grupos: esportivo e não esportivo, foram confrontados para efeito de análise. Os resultados desta pesquisa permitiram identificar semelhança dos grupos dentre outras, quanto aos aspectos relacionados às drogas e crimes, ao tratamento recebido, assim como no reconhecimento para com as instituições. Considere-se que os grupos são similares na relação institucional, e que o bom tratamento é um item comum e pode responder pela real eficácia dos processos positivamente resultantes do afastamento das drogas e da criminalidade, ficando essas manifestações, inclusive a esportiva, como veículos onde atenção, respeito, educação, valorização do individuo etc, são evidenciadas, e não o esporte em si.
The theme of this study focuses over the perspective created around sport, as means to keep children and adolescents away fro drugs and criminality in the city of Rio de Janeiro, where projects sponsored by public or private institutions, located in favelas (slums) and without payment by the participants, gather thousands of persons of various ages, particularly children and adolescents, for sportive activities, as well as non-sportive too. The methodology of the study focused on the sampling and analysis of information via field researches, where a semi-open survey was applied to boys between the age of 7 and 17, which were affiliate with public or private institutions that offered activities related to sports, arts, music and religion, highlighting the qualitative aspects of the research where the comparison of results in two groups: Sportive and nonsportive, were confronted for analyzing purposes. The results of this research permitted the identification of similarities between this groups, in which, among others, about aspects related to drugs and crimes, to the received treatment, as well as in the recognition for the institutions. We might consider so, that the groups are similar in the institutional relation, and that the good treatment is a common item, being able to answer for the real efficacy of this positively resulting processes of disconnection from drugs and criminality, staying these manifestations, including sports, as vehicles, where care, respect, education, valorization of the selfhood, etc, are evidenced, not sport by itself.
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Freitas, Elisa Isabel Serrão. « A metodologia da expressão dramática como auxiliar para as relações de género : o caso da turma de 3º ano do 1º ciclo da Escola EB 1 Nº 6 Vila Real (2014-2015) ». Master's thesis, 2016. http://hdl.handle.net/10348/7013.
Résumé :
Dissertação de Mestrado em Ensino de TeatroO presente relatório com feição dissertativa pretende descrever, analisar e refletir sobre o estágio I e II realizado no Agrupamento Vertical de Escolas Diogo Cão, mais particularmente na Escola Básica l n.º 6 de Vila Real, para obtenção do grau de Mestre no Mestrado em Ensino de Teatro na Universidade de Trás-os-Montes e Alto Douro. Este documento contempla uma fundamentação teórica e prática, bem como análise reflexiva acerca da temática de “A metodologia da expressão dramática como auxiliar para as relações de género no lº ciclo do ensino básico”. Com este estudo pretendemos salientar a importância da metodologia da expressão dramática como ferramenta para a transformação das relações de género no ambiente escolar, pois a escola é um espaço privilegiado para o desenvolvimento pessoal e social. O objetivo principal deste trabalho é refletir relativamente sobre os benifícios que a expressão dramática proporciona às crianças e qual o seu contributo para o valor pedagógico nas relações de género no lº ciclo do ensino básico. Procuramos aliar a prática à teoria, debruçando-nos sobre estudos relacionados com a expressão dramática, o jogo dramático, o teatro infantil e as relações de género para podermos compreender que é absolutamente necessário utilizar métodos diferentes quando trabalhamos com um público tão exigente como são as crianças.
This report feature dissertation aims to describe, analyze and reflect on the first and second stage held in Agrupamento Vertical de Escolas Diogo Cão, more particularly in lst cycle Basic School n.º 6 of Vila Real, for the degree of Master in the Master of Theatre education at the University of Trás- os- Montes e Alto Douro. This document includes theoretical and practical reasoning and reflective analysis on the subject of "The methodology of drama as a benefit to gender relations in the lst cycle of basic education." With this study we intend to notice the importance of the methodology of drama as a tool for the transformation of gender relations at school, because the school is a privileged space for personal and social development. The main objective of this work is to reflect about the benefits that drama provides on children and what their contribution to the educational value of gender relations in the lst cycle of basic education. We seek to combine the practice and the theory, addressing us about studies related to the drama, dramatic play, children's theater and gender relations in order to understand that it is absolutely necessary to use different methods when working with an audience as demanding as are the children.
Livres sur le sujet "796.045 6":
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Green, Ronald M., dir. Religion and Sexual Health. Dordrecht : Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-015-7963-6.
2
Yearbook of Finnish foreign policy 1992. Helsinki : Finnish institute of international affairs, 1992.
Chapitres de livres sur le sujet "796.045 6":
1
« § 6 Wahlvorschläge ». Dans § 117 ; MitbestR ; Nachtrag § 76 Abs 4, 495–500. De Gruyter, 2018. http://dx.doi.org/10.1515/9783110294149-048.
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Günaydın, Gülseren, et Mustafa Günaydın. « 6 Şubat 2023 Kahramanmaraş Depremi ». Dans Sosyal Bilimlerde Akademik Araştırma ve Değerlendirmeler - III. Özgür Yayınları, 2023. http://dx.doi.org/10.58830/ozgur.pub310.c1426.
Résumé :
Son zamanlarda ülkemizde birçok doğa kaynaklı afet olayı yaşanmıştır. Bu afetlerin en geniş ve ağır kayıpların oluştuğu son afet olayı Kahramanmaraş depremidir. 06.02.2023 tarihinde saat 04:17 sularında Kahramanmaraş ili Pazarcık merkezli 7.7 büyüklüğünde ve 13:24’de merkez üssü Elbistan Merkezli 7.6 büyüklüğünde iki deprem meydana gelmiştir. Bu depremler sonrasında da birçok artçı deprem yaşanmış ve başta Kahramanmaraş, Hatay, Adana, Malatya, Adıyaman, Gaziantep, Şanlıurfa, Diyarbakır, Osmaniye, Kilis ve sonradan da Elazığ ilinin de eklenmesiyle toplamda 11 ilimizi çok şiddetli bir şekilde etkilemiş ve ülkemizin çoğu ilinde de hissedilmiştir. Olaya yerine olayın yaşandığı ilk saatlerde ulaşılmaya çalışılmış, ancak bazı illerde hava ve karayollarında meydana gelen ciddi hasarlardan dolayı zamanında ulaşılamamıştır. Deprem nedeniyle 50.783 kişi hayatını kaybetmiş, 115.353 kişi yaralanmış ve 37.984 binanın yıkıldığı rapor edilmiştir. Deprem sonrası tüm Türkiye tek yürek olmuş elinden gelen her türlü yardımı yapmak ve göndermek amacıyla tüm halkı, kurum ve kuruluşlarıyla birlik ve beraberliği açıkça göstermiştir.
3
de Kreij, Mark. « The Pocket Pindar The Antinoupolis Codex and Pindar’s Readership in Graeco-Roman Egypt ». Dans Antichistica. Venice : Fondazione Università Ca’ Foscari, 2021. http://dx.doi.org/10.30687/978-88-6969-548-3/015.
Résumé :
The parchment codex published as P.Ant. II 76 and III 212 contains remains of Pindar’s Olympians 5 and 6 along with scanty traces of marginal notes. Further conservation and study allows us to now roughly reconstruct the format of the original manuscript, and new imaging techniques have revealed better readings of the marginalia. In this speculative article, I explore the Pindar codex’s form, content, and the particular context of Antinoupolis. In the process, I touch upon the question of Pindar’s popularity in Roman Egypt, book production in Antinoupolis, and the form and function of the early codex. Taking all available evidence into account, I propose that we might have a pocket codex of Pindar’s complete works – perhaps intended for casual reading.
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Kent, Alison, Shamez N. Ladhani, Nick J. Andrews, Tim Scorrer, Andrew J. Pollard, Paul Clarke, Stephen M. Hughes et al. « Schedules for Pneumococcal Vaccination of Preterm Infants : An RCT ». Dans Immunization Strategies and Practices, 18–32. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/9781610022774-schedules.
Résumé :
BACKGROUND AND OBJECTIVE Premature infants have a higher risk of invasive pneumococcal disease and are more likely to have lower vaccine responses compared with term infants. Increasingly, immunization schedules are including a reduced, 2-dose, pneumococcal conjugate vaccine priming schedule. Our goal was to assess the immunogenicity of 3 commonly used 13-valent pneumococcal conjugate vaccine (PCV13) priming schedules in premature infants and their response to a 12-month booster dose. METHODS Premature infants (<35 weeks’ gestation) were randomized to receive PCV13 at 2 and 4 months (reduced schedule); 2, 3, and 4 months (accelerated schedule); or 2, 4, and 6 months (extended schedule). All infants received a 12-month PCV13 booster. Serotype-specific pneumococcal immunoglobulin G (IgG) for PCV13 serotypes was measured by using enzyme-linked immunosorbent assay 1 month after the primary and booster vaccinations. RESULTS A total of 210 infants (median birth gestation, 29+6 weeks; range, 23+2–34+6 weeks) were included. After the primary vaccination, 75% (95% confidence interval [CI], 62–85), 88% (95% CI, 76–95), and 97% (95% CI, 87–99) of participants had protective antibody concentrations for at least one-half the PCV13 serotypes for the reduced, accelerated, and extended schedules, respectively. After the booster vaccination, participants receiving the extended schedule had significantly lower (P < .05) geometric mean concentrations compared with reduced (for 9 of 13 serotypes) and accelerated (for 4 of 13 serotypes) schedules, but nearly all participations, regardless of schedule or serotype, had seroprotective IgG concentrations. CONCLUSIONS A reduced priming schedule of PCV13 resulted in higher post-booster IgG concentrations but lower post-primary concentrations. The optimum vaccine schedule for preterm infants will therefore depend on when they are most at risk for invasive pneumococcal disease.
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Yıldız, Gıyasettin. « Depremin Ardından : Travmatik Deneyimin Anlamlandırılma Süreci ve Kültürel Bağlamları ». Dans Sosyal Bilimlerde Akademik Araştırma ve Değerlendirmeler - I. Özgür Yayınları, 2023. http://dx.doi.org/10.58830/ozgur.pub308.c1402.
Résumé :
6 Şubat 2023 tarihinde, saat 04:17 ve 13:24'te merkez üssü Kahramanmaraş olan 7.7 ve 7.6 büyüklüğünde yıkıcı bir deprem meydana gelmiştir. Bu felaket 11 ili etkilemiş, 55.000'den fazla kişinin ölümüne ve yaklaşık 110.000 kişinin yaralanmasına yol açmıştır. Deprem, 36.000'den fazla bina ve işyerinin yıkılmasıyla ülke tarihindeki en büyük felaket olarak kayıtlara geçmiştir. Bu deprem, beklenildiği gibi yalnızca ani bir yıkıma yol açmakla kalmamış 14 milyona yakın insanın yaşamında çok önemli değişiklikleri de başlatmıştır. Bu geniş çaplı yıkım, doğal olarak hem toplumsal yapıda hem de depremden etkilenenlerin ruhsal dünyalarında inkâr edilemez derin izler bırakmıştır. Bu etkilerin yansımalarını derinlemesine incelemek, toplumsal yapının sağlıklı bir şekilde devam etmesinde oldukça önemli rol oynayacaktır. Bu nedenle araştırmanın metodolojisi olarak fenomenolojik desen kullanılarak nitel bir keşif gerçekleştirilmiştir. Görüşmeler, Adıyaman, Hayat ve Kahramanmaraş illerinden Konya’ın Akşehir ilçesine göç etmiş 23 kişilik bir grupla yarı yapılandırılmış görüşme formu kullanılarak gerçekleştirilmiştir. Bu araştırmadan elde edilen bulgular, depremden etkilenenlerin zihinsel dünyalarına ilişkin çeşitli iç görüleri ortaya koymayı hedeflemektedir. Katılımcılar, deprem anı ve sonrasında ölümün yadsınamaz varlığını hatırladıklarını, psikolojik açıdan travmaya yol açan üzücü hatıralardan etkilendiklerini ve yaşananları afet öncesi hayatları hakkında iç gözlem yapmalarına neden olan ilahî bir işaret olarak yorumladıkları üzerinde durmaktadırlar. Bu çarpıcı ifşaatlar, deprem gibi büyük ölçekli olayların kapsamlı bir sosyolojik analizinin gerekliliğini vurgulamaktadır. Bu sebeple afet sonrası çalışmaları bireysel psikolojik travma değerlendirmeleriyle sınırlandırmak yerine, uzun süreli yansımalarının gelecek nesilleri etkileme ihtimali göz önüne alınarak kolektif travmatik deneyimleri de ele almak son derece önem arz etmektedir.
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Feather, Leonard, et Ira Gitler. « l ». Dans The Biographical Encyclopedia of Jazz, 395–424. Oxford University PressNew York, NY, 1999. http://dx.doi.org/10.1093/oso/9780195074185.003.0012.
Résumé :
Abstract La porta, john d., cl., saxes, comp, arr; b. Philadelphia, PA, 4/1/20; d. Sarasota, FL, 5/12/04. Began on cl. at age 9. Stud. cl. w. Wm. Dietrich, Joseph Gigliotti, Leon Russianoff 1932–57. Pl. in Youth Symph. cond. by Leopold Stokowski ’37–8. Stud. comp. w. Ernst Toch, Alexis Haieff ’45–6; improv. w. Lennie Tristano ’47–8; received B. Mus. ’56, M. Mus. Ed. ’57 fr. Manh. Sch. of Mus. Pl. w. Bob Chester, Richard Himber, Ray McKinley early ’40s; Woody Herman ’44–6; Tristano late ’40s; Charles Mingus ’50–67; Metronome All-Stars ’51–2; own gps ’51–62. Founding member and mus. dir. of Jazz Composers Wkshp. ’52–4. App. w. Gunther Schuller at Brandeis Mus. Fest. ’57; Leonard Bernstein and N.Y. Philharm. perf. Teo Macero’s Fusion ’58–9. Taught at Parkway Mus. Inst., Bklyn. ’48–51. Reed coach for Marshall Brown’s Newport Youth Band ’53–8. Active as clinician ’59–81. Taught at Manh. Sch. of Mus. ’60–2; Berklee Sch. of Mus. fr. ’62. Dir. Greater Bost. HS Stage Band ’64–5. Pl. w. Bost. Sax Qt. w. Charlie Mariano ’60s; Berklee Sax Qt. fr. ’62; Herb Pomeroy Orch fr. ’76; John La Porta–Bob Winter Duo fr. ’81. La Porta was a founding member of the Nat’l Assoc. of Jazz Educs. and the author of eight instructional texts, incl. Tonal Organization of Improv. Techniques (Kendor); Guide to Improv. (Berklee); Guide to Jazz Phrasing and Interpretation (Berklee). His numerous arrs. for hs band are publ. by Berklee, Kendor, and Marshall Brown Music. La Porta taught and lectured at Berklee and in Fla. Polls: Play. ’61; NAJE Award ’86; Berklee Award ’87. Fests: all major ’50s–’60s. Film: Trocadero w. Bob Chester Orch. perf. La Porta comp. ’42. CDs: w. C. Parker (Verve); T. Macero (Stash); C. Mingus (Deb; Sav.; Atl.); W. Herman (Col.); H. Mobley (Sav.); H. Merrill (Em.; Verve).
Actes de conférences sur le sujet "796.045 6":
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Giannessi, D., R. De Caterina, G. Lazzerini, R. Sicari et P. Gazzetti. « RELATIVE SENSITIVITY OF CARDIAC PROSTACYCLIN AND THROMBOXANE TO INHIBITION BY NON-STEROIDAL ANTIINFLAMMATORY DRUGS IN THE RAT HEART ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643390.
Résumé :
We have previously shown that the isolated perfused rat Langendorff heart is able to synthesize detectable amounts of thromboxane (TX) A2, as well as prostacyclin (PGI2). Eicosanoid production in this system is increased during post-ischemic reperfusion, reflecting greater availability of substrate and net increase of synthesis. We assessed relative sensitivity of cyclooxygenases synthesizing TX and prostacyclin (probably located in different cell types) to aspirin (0.1, 0.5, 1 g/1), ibuprofen (1, 10, 80, 160, 320 mg/1) and diclofenac (0.01, 0.1, 0.5, 2.5, 5, 10, 25 mg/1), by radioimmunoassays of TXB2 and 6-keto-PGFα in the perfusate. Sixty Wistar male rat hearts were perfused with buffer containing control vehicle or drugs for 30 min, followed by 5 min clamping of the perfusion line and subsequent post-ischemic reperfusion. Baseline production was (mean±SD, pg/min/g wet weight) 754±261 and 143±66 for PGI2 and TXA2, respectively. Peak post-ischemic production was 7628±2673 and 1036±135, respectively. At doses of aspirin, ibuprofen and diclofenac (100, 10 and 2.5 mg/1, respectively) which were equally effective on prostacyclin production (mean % inhibition: 68, 67 and 72 for basal production and 90, 86 and 85 for peak post-ischemic production, respectively), % inhibition of TX production was consistently less, but also similar for the three drugs: 55, 58 and 56 for basal production and 78, 81 and 76 for peak post-ischemic production, for aspirin, ibuprofen and diclofenac, respectively; difference between inhibition of prostacyclin and TX: P < .01, difference for subsets among different drugs: N.S.). TX production was, on the contrary, selectively inhibited by the TX-synthase inhibitor 0KY 046 (by 79 and 92% at 0.1 mg/1, versus a complete sparing of prostacyclin production). The lesser sensitivity of cardiac (vascular?) TX versus prostacyclin to non-steroidal antiinflammatory drugs (NSAIDs) inhibition and the similar degree of inhibition by various NSAIDs, differing in structure and diffusing capacity, suggest heterogeneity among cyclooxygenases present in the system and different intrinsic sensitivity of TX- from prostacyclin-producing cyclooxygenases.
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Munggara, Mumung Ridhuan, Nita Handayani et Fajar Arianto. « Calculation of Absorbed Dose of <sup>103</sup>Pd and <sup>131</sup>Cs Sources in Prostate Cancer Brachytherapy Simulation Using Monte Carlo N-Particle 6 (MCNP-6) Software ». Dans The 6th International Conference on Science and Engineering. Switzerland : Trans Tech Publications Ltd, 2024. http://dx.doi.org/10.4028/p-g56t9j.
Résumé :
Implant brachytherapy is one of the therapies for Low Dose Rate (LDR) in prostate cancer. This type of therapy uses a source with low energy and penetration rate so that the organs around the prostate do not receive much of the absorbed dose. This study uses a calculation method Monte Carlo N-Particle 6 (MCNP-6) to calculate the interaction of photons with organ materials. The main objective of this research is to determine the number of seeds and the ideal source activity to achieve the optimal absorbed dose in the prostate and provide the minimum absorbed dose in the surrounding organs. Organs around the prostate include the testes, small intestine, descending colon wall, descending colon, sigmoid colon wall, bladder wall, and bladder. This study uses two types of radioisotope sources namely 103Pd and 131Cs which each has a photon energy of 21 keV and 30 keV. Variations made is the addition of the number of seeds from 60 to 100 at intervals of 8 seeds symmetrically away from the center of the prostate and variation of source activity from 0.1 mCi to 0.6 mCi at intervals of 0.1 mCi for each type of source. Results of this study obtained the relationship that the more the number of seeds the greater the dose received by the prostate and surrounding organs, as well as the addition of source activity. The effect of increasing the number of seeds can increase the absorbed dose more significantly than the effect of adding activity to the organs around the prostate. Optimal absorbed dose for 103Pd is 125 Gy and 115 Gy for 131Cs. Based on the simulation results with MCNP-6, it is obtained that the ideal combination for the optimal absorbed dose is obtained from the source 103Pd is the number of seed 60 with 0.3 mCi activity, and source 131Cs is the number of seed 76 with an activity of 0.5 mCi. Source 103Pd provides a lower absorbed dose to the organs around the prostate compared to the source 131Cs.
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Тимкина, Н. В., А. В. Симаненкова, А. Л. Григорьева, В. А. Коробкова, Ф. М. Радугин et Т. Л. Каронова. « ВЛИЯНИЕ ТЕРАПИИ ИНГИБИТОРАМИ НАТРИЙ-ГЛЮКОЗНОГО КОТРАНСПОРТЕРА 2 ТИПА ; НА ПАРАМЕТРЫ КОСТНОГО ОБМЕНА У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2 ТИПА ». Dans X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-299.
Résumé :
Больные сахарным диабетом (СД) 2 типа имеют повышенный риск переломов. Динамика минеральной
плотности костной ткани (МПК) и маркеров костного обмена при использовании современных сахароснижающих препаратов остается предметом обсуждений.
ЦЕЛЬ: изучение параметров костного обмена на фоне терапии препаратами иНГЛТ-2.
МАТЕРИАЛЫ И МЕТОДЫ: из 120 пациентов с СД 2 типа 45-75 лет выбрано 50 пациентов (30 женщин,
60%), нуждающихся в интенсификации терапии. Критерии исключения: остеопороз, прием колекальциферола в дозе, выше профилактической, рСКФ ниже 45 мл/мин/1,73 м2
. Выполнена рентгеновская денситометрия (DXA) с определением трабекулярного костного индекса (ТКИ), 10-летний риск переломов рассчитан
с помощью калькулятора FRAX. Терапия усилена препаратами иНГЛТ-2 (канаглифлозин, дапаглифлозин,
эмпаглифлозин). Исходно и через 6 месяцев терапии оценивался уровень 25(ОН)D (Abbot, США); кальция,
фосфора, креатинина (Roсhe Diagnostics, Швейцария); фактора роста фибробластов-23 (ФРФ-23), лиганда
рецептора активатора ядерного фактора каппа-бета (RANKL), остеопротегерина (Biomedica, Австрия);
паратиреоидного гормона (ПТГ, DIAsource ImmunoAssay, Бельгия), остеокальцина (IDS, Великобритания).
Выборка описана с помощью медианы и квартилей, для сравнения связанных выборок использовался
критерий Вилкоксона, а для исследования корреляций – критерий Пирсона.
РЕЗУЛЬТАТЫ: возраст пациентов составил 58 [50;64] лет, длительность заболевания – 6 [2; 10] лет,
уровень HbA1c 8,3 [7,6;9,1]%, ИМТ – 33,9 [30,4; 37,0] кг/м2
; 10-летний риск основных остеопоротических
переломов – 6,5 [5,2; 7,6]%, риск перелома бедра – 0,25 [0,1; 0,5]%. При расчете FRAX с поправкой на ТКИ
показатели риска составили 7,4 [4,9; 9,4]% и 0,2 [0,1; 0,5]% соответственно. У четырёх пациентов (9,5%)
выявлена остеопения, деградированная микроархитектоника костной ткани обнаружена у 14 пациентов
(28%), частично деградированная – у 17 (34%). Дефицит витамина D был диагностирован у 22 пациентов
(44%), а его недостаточность – у 13 (26 %). Корреляционных связей между уровнем HbA1c, возрастом, длительностью СД и МПК, а также ТКИ не выявлено, но была обнаружена положительная корреляция (r=0,36,
p=0,01) между ИМТ и МПК. Добавление к терапии иНГЛТ-2 привело к снижению уровня HbA1c с 8,3 [7,6;9,1]%
до 7,8 [7,2; 8,1]% (р <0,05), ИМТ – с 33,9 [30,4; 37,0] кг/м2
до 32,9 [30,1; 37,4] кг/м2 (р < 0,01). Изменений в уровне
кальция, фосфора, креатинина, ПТГ, 25(ОН)D, остеопротегерина и RANKL не было. Однако, отмечено повышение концентрации ФРФ-23 с 1,0 пмоль/л [0,98; 1,32] до 1,21 [1,01; 1,42] пмоль/л, p < 0,05) и остеокальцина
с 10,4 [8,1; 13,6] нг/мл до 11,4 [10,2; 14,4] нг/мл, р= 0,06.
ВЫВОДЫ: терапия иНГЛТ-2 может способствовать повышению ФРФ-23, но в краткосрочном периоде
это не приводит к изменению ПТГ. Улучшение гликемического контроля может стимулировать костеобразование, что выражается в некотором повышении остеокальцина.
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Admiraal, Wilfried, et Irma Heemskerk. « ONLINE WORKSPACES TO SUPPORT TEACHER COMMUNITIES IN SECONDARY SCHOOLS ». Dans eLSE 2012. Editura Universitara, 2012. http://dx.doi.org/10.12753/2066-026x-12-065.
Résumé :
Introduction There are steadily expanding claims that teacher community contributes to the improvement in the practices of teaching and schooling (cf., Witziers et al., 1999; Little, 2003; Darling-Hammond and Bransford, 2005) as well as individual teacher development and the collective capacity schools (cf., Seashore Louis et al., 1996; Grossman et al., 2001; Imants et al., 2001; Achinstein, 2002; Piazza et al., 2009). In line with Grossman et al. (2001), we are interested in teacher community at the local level, where interaction, dialogue and trust are necessary elements of building cohesion. Based on the definition of community by Bellah et al (1985), we define a teacher community as ‘a group of teachers who are socially interdependent, who participate together in discussion and decision making, and share and build knowledge with a group identity, shared domain and goals, and shared interactional repertoire’. This means that we distinguish three core features of a teacher community: group identity, shared domain and goals, and shared interactional repertoire. These features refers to the nature of a community (group identity), what a community is about (shared domain), and how it functions (shared interactional repertoire). In a literature review of Brouwer et al. (in press), 31 design principles have been retrieved from the literature about the setup of efficient and effective teacher communities in schools. Examples of design principles are the promotion of interdependence, shared responsibility and individual accountability, the development of guidelines for dealing with conflicts and decision-making, and the consideration of group size and heterogeneity of expertise. The use of online workspaces might solve issues in communication and collaboration of school teachers as well as in establishing feelings of cohesion and trust –in addition to face-to-face interaction and collaboration. However, the problem is that we do not know how online workspace should be designed in order to efficiently and effectively communities of teachers in secondary school. Method and results A systematic review will be presented of online workspaces from the perspective of how teacher communities should be designed in order to effectively and efficiently support collaboration and communication of teachers in secondary schools. These tools includes tools for collaborative writing, file sharing, mind mapping, group communication, social networking, wikis and blogs, web presenting, whiteboarding, web and video conferencing, chat and instant messaging, and project management and event scheduling. Subsequently, online collaboration tools are evaluated on the way their functionalities potentially facilitate the design principles that have been worked out. Literature Achinstein, B. (2002), “Conflict amid community: The micropolitics of teacher collaboration”, Teacher College Record, Vol.104 No.3, pp.421-455. Bellah, R. N., Madsen, N., Sullivan, W. M., Swidler, A., & Tipton, S. M. (1985). Habits of the heart; Individualism and commitment in American life. Berkeley, CA: University of Calidofornia Press. Brouwer, P., Brekelmans, M., Nieuwenhuis, L., & Simons, P. R. J. (in press). Fostering teacher community development A review of design principles and a case study of an innovative interdisciplinary team. Learning Environments Research. Darling-Hammond, L. and Bransford, J. (Eds.) (2005), Preparing teachers for a changing world. What teachers should learn and be able to do, Jossey-Bass, San Francisco. Grossman, P., Wineburg, S., & Woolworth, S. (2001). Toward a theory of teacher community. Teacher College Record, 103, 942-1012. Imants, J., Sleegers, P. and Witziers, B. (2001), “The tension between sub-structures in secondary schools and educational reform”, School Leadership & Management, Vol.21, No.3, pp.289-307. Little, J. W. (2003), “Inside teacher community: representations of classroom practice”, Teachers College Record, Vol.105 No.6, pp.913-945. Piazza, P., McNeill, K.L. and Hittinger, J. (2009), “Developing a voluntary teacher community: The role of professional development, collaborative learning and conflict”, Paper presented at the annual meeting of the American Educational Research Association, April, San Diego, CA. Seashore Louis, K., Marks, H. and Kruse, S. (1996), “Teachers’ professional community in restructuring schools.” American Educational Research Journal, Vol.33 No.4, pp.757-798. Witziers, B., Sleegers, P. and Imants, J. (1999), “Departments as teams: functioning, variations and alternatives”, School Leadership & Management, Vol.19 No.3, pp.293- 304.
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Stuart, M. J., P. D. Sadowitz et B. N. Y. Setty. « PLATELET 12-HYDROXY-5,8,10-HEPTADECATRIENOIC ACID (HHT) STIMULATES PROSTACYCLIN PRODUCTION BY ENDOTHELIAL CELLS ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642836.
Résumé :
Although HHT accounts for approximately one third of the ara-chidonic acid (AA) metabolites produced by stimulated platelets, no well defined function has been attributed to this platelet product. We report that HHT stimulates prostacyclin production by endothelial cells, and have identified the mechanism for this effect. In human umbilical venous endothelial cells HHT (0.5 and 1pM) stimulated prostacyclin (RIA for 6KPGF1α) by 32±10% (1 SE) and 42±13% (P<0.05 and (0.01). Similar changes were observed when the effect of HHT on exogenous [1 -14C] AA metabolism in fetal bovine aortic endothelial cells (FBAECs) was studied. 6KPGF1α was stimulated by 25±9% and 30±6% at HHT cones, of 0.5 and 1μM (P<0.05) . While prelabelling experiments with [1-14c] AA revealed that HHT (1μM) did not affect the ionophore stimulated release of AA from FBAEC membrane lipids (29521±11837 cpm/well control vs 32458+8811 in HHT treated cells, mean ±1SD) kinetic analyses revealed that HHT affected vascular cyclooxygenase. HHT (1μM) increased Vmax in test microsomes (706±21 pmol/mg/min) when compared to controls (529±20; P<0.02). No effect on Km was observed (6.2±0.3μM control vs. 7.2±0.4 in HHT treated microsomes). The effect of HHT on platelet AA metabolism was next studied. Preincubation of washed platelets with HHT (1μM) did not enhance thrombin (0.2 U/ml) induced pit. TXB2 (2.27±1.34 pmol/106 platelets control vs 2.28±1.62 in HHT treated platelets). In platelets prelabelled with [ 1-14c] AA, HHT (1μM) also had no effect on AA release post thrombin stimulation (5794_423 cpm per 108 platelets control vs. 6135±612 for paired HHT treated cells). Conversion to cyclooxygenase metabolites was also not enhanced (2605±265 vs 2806±332 for test platelets). HHT thus stimulates vascular prostacyclin without a concomitant effect on platelet AA metabolism. Our findings may explain the discrepancies relative to prostacyclin production in atherosclerosis and diabetes. In these disorders while ex vivo production of prostacyclin by vascular tissue is decreased, in vivo production is elevated. HHT may also be an important local modulator of platelet plug formation and could play a protective antithrombotic role by its hitherto unrecognized effect on vascular prostacyclin.
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Altman, Brianna, Maha Mian, Luna Ueno et Mitch Earleywine. « Average Intoxication as a Proxy for Cannabis Use ». Dans 2020 Virtual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2021. http://dx.doi.org/10.26828/cannabis.2021.01.000.4.
Résumé :
Assessing cannabis use is challenging due to the lack of standardized doses, differing potencies among products, and the potential for sharing with others. Although legalization of cannabis might give users a better sense of the quantity purchased and THC/CBD composition of products, issues in assessment and measurement can still preclude researchers from understanding use patterns. Given these challenges, the present work examines whether an individual’s average level of intoxication after cannabis consumption might serve as a better proxy for cannabis use than quantity of use. Data was aggregated from several studies related to cannabis use and health behaviors and collapsed across common variables (N = 2,659, Mean age = 34.08, 61.9% Male, 84.8% Caucasian). Our sample reported using cannabis either six or seven days per week, consuming approximately 1.12 ounces of cannabis per month (SD = .35 ounces), attaining an average intoxication of 3.49 on a scale from 0 (“Not at all”) to 6 (“Extremely high;” SD = 1.21), and experiencing a mild amount of cannabis-induced impairment as measured by the Cannabis-Associated Problems Questionnaire (CAPQ; M = 8.21, SD = 9.08). In this sample of frequent users, average intoxication levels were significantly related to cannabis problems (r = .153, p < .001) while quantity per month appeared to be unrelated (r = .005, p = .798). Using Meng’s (1992) procedure for comparing correlated correlation coefficients, these relations were found to significantly differ from each other (Z = - 5.53, p < .001). Our results provide preliminary evidence supporting cannabis-induced intoxication as a better proxy for cannabis use than quantity consumed. Individuals might more accurately remember their experiences of being high as opposed to recalling how much they consumed over a month’s span. Future work should continue to examine relations between intoxication and other indices of cannabis use to confirm and extend our findings.
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MAZHAYSKY, Yuri, Tatyana GUSEVA et Otilija MISECKAITĖ. « INTEGRATED MELIORATION MEASURES ON RESTORATION OF POLLUTED AND DEGRADED SOILS FERTILITY ». Dans Rural Development 2015. Aleksandras Stulginskis University, 2015. http://dx.doi.org/10.15544/rd.2015.044.
Résumé :
In case of significant technogenic geochemical loads on agricultural landscapes, the issue of ecological forecasting of environmental management is particularly important. Scientific studies of this issue are aimed at establishing the critical values for the components of the ecosystem, the classification of technogenic sources of hazardous substances, levels of soil contamination. This study presents a research to determine the content of heavy metals in the soils of the Ryazan region (Russia) and analyzed the level of their pollution. In the experiments organic, organomineral and mineral fertilizers systems were studied. From 2002 to 2008 were conducted lysimetric experiments on detoxification of elevated pollution of sod-podzol sandy loam soil, and from 2006 to 2008 of podzolized black soil. The participation of the non-ferrous metals plant emissions was detected in the pollution of sod-podzol light in granulometric composition soils with copper of up to 80 mg·kg-1, when the average concentration of Cu in the soil was 38.8 ±6 mg·kg-1. Humification plays a significant role in the formation of soil, its most important properties and characteristics. The saturation of 1 hectare of sown area with organic was slightly different in the experiments, but the intensity of accumulation of humus from the various agrochemical means did not almost differ. The problem of adaptation of plants in the conditions of technogenic environment is of primary importance. Plants have three biobarera against the admission of toxicants, these are the soil – the root – the stem – the reproductive organs. Grain in contaminated soil is environmentally hazardous as the content of Pb is indicated at the level of 0.68, 1.17 mg·kg-1 (MPC 0.5), Cd – 0.27, 0.11 mg·kg-1 (MPC 0.1), Zn – 76 mg·kg-1 (50 MPC). Use of fertilizing systems had a mostly positive effect, but products do not always become environmentally friendly.
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Graef, George. « High-yield soybean lines with improved seed protein and oil balance ». Dans 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/reen3740.
Résumé :
Soybean [Glycine max (L.) Merr.] is a leading supplier of vegetable oil and high-quality protein meal in world markets. Processors expect an oil yield of at least 11 lb bu-1 and want to produce a 48% protein meal. On-farm soybean yields show a linear increase of ~0.45 bu a-1 yr-1, but the prevalent negative association between yield and seed protein concentration resulted in a decrease in seed protein of ~2 percentage points during the past 80 years. Seed oil concentration typically is slightly positively associated with yield and highly negatively correlated with protein, and estimates for the 2021 US soybean extraction rate indicate an all-time high of 11.9 lb bu-1. More extreme levels of protein or oil in the seed have been achieved, but trade-offs with yield and/or the other major component make those soybean lines unsuitable for the commodity market. With large projected increases in demand for both oil and protein, a commodity bean with improved balance of major components that meets the needs of the farmer and processor is needed. By focusing on processing outputs, we realized an improved balance of seed components between protein, oil, and soluble carbohydrates. In multi-environment trials over years, the improved soybean lines yield as well as the elite checks, produce a 48% meal and yield ~1.5 pounds of oil per bushel. In Nebraska tests over two years and 6 locations, new lines showed elite yields (76-86 bu a-1) equal to the checks, produce a 48% protein meal and yield 12.7 pounds of oil per bushel. With judicious choice of parental lines, evaluation and selection based on multiple seed traits and yield, it is possible to increase both oil and protein concentration in the seed and achieve elite yields for commodity markets. These soybeans can help meet the growing demand for both soy protein and oil and provide improved yield and quality for farmers and processors.
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Долидзе, Д. Д., Д. В. Слепухова, С. Д. Кованцев, И. Н. Лебединский, Д. Л. Ротин, М. М. Шунин, М. М. Магомедова et Н. В. Пичугина. « ПЕРВЫЕ РЕЗУЛЬТАТЫ ПРИМЕНЕНИЯ УСОВЕРШЕНСТВОВАННОЙ МЕТОДИКИ ; ОПЕРАТИВНОГО ЛЕЧЕНИЯ ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ БОЛЕЗНЬЮ ПОЧЕК ; И ВТОРИЧНЫМ ГИПЕРПАРАТИРЕОЗОМ ». Dans X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-246.
Résumé :
ЦЕЛЬ: оценить результаты хирургического лечения больных с вторичным гиперпаратиреозом (ВГПТ)
на фоне терминальной стадии хронической болезни почек (ХБП) при применении усовершенствованного
способа операции.
МАТЕРИАЛЫ И МЕТОДЫ: Боткинской больницей был предложен модифицированный способ хирургического лечения пациентов с ВГПТ. В исследование включено 9 пациентов с ХБП 5 стадии и ВГПТ (мужчин – 2, женщин – 7). Средний возраст наблюдаемых 43,4±0,5 лет. В дооперационном периоде пациентам
выполнены ультразвуковое исследование (УЗИ) области шеи, сцинтиграфия околощитовидных желез
(ОЩЖ) и компьютерная томография (КТ) шеи и грудной клетки с контрастным усилением. На момент операции все пациенты имели лабораторно подтвержденный гиперпаратиреоз в течение не менее 6 месяцев,
на фоне максимальной медикаментозной терапии. Всем больным было выполнено модифицированное
оперативное лечение, заключающееся в выполнении прецизионной субтотальной паратиреоидэктомии
с перемещением фрагмента наименее измененной нижней ОЩЖ на собственной сосудистой ножке в предгортанные мышцы. На операции обязательными этапами были мобилизация и удаление паратрахеальной
клетчатки с обеих сторон, и резекция верхнего полюса тимуса (для повышения радикальности, ввиду
возможного нахождения в данных структурах фрагментов или дополнительных ОЩЖ). В 1 (11,1%) случае
у пациента по данным сцинтиграфии и КТ визуализирована аденома ОЩЖ, расположенная в переднем
средостение на дуге аорты. Этому больному оперативное лечение было выполнено одномоментно в два
этапа: торакоскопическое удаление образования переднего средостения и применен модифицированный
подход в области шеи. Минимальный уровень паратгормона (ПТГ) у наблюдаемых был 798 пг/мл, максимальный – 1568 пг/мл, в средним – 908 пг/мл. Средняя длительность операции составила 140,20±25 мин.
Всем пациентам проводился интраоперационный мониторинг ПТГ.
РЕЗУЛЬТАТЫ: при анализе результатов в 8 (88,9%) случаях отмечено снижение уровня ПТГ более чем на 90% (92% – 98%) от исходного уровня. В одном наблюдении уровень ПТГ снизился на 43%.
Послеоперационных осложнений не было. Во всех случаях отмечалось транзиторное снижение уровня общего кальция крови. Явления послеоперационного гипопаратиреоза ликвидированы в течение 2-3 недель
на фоне медикаментозной терапии препаратами кальция. На 2-3 сутки выполнялось УЗИ шеи в области
операции (в режиме доплеровского картирования) для визуализации ОЩЖ, оценки ее размеров и кровоснабжения. Средняя длительность пребывания в стационаре после операции составила 5 (от 4 до 10) суток. При динамическом амбулаторном наблюдении у всех 9 (100%) пациентов при УЗИ визуализирована
ОЩЖ с питающим сосудом, без динамики роста. У 8 (88,9%) больных уровень ПТГ варьировал в диапазоне
32,1-73,8 пг/мл, у 1 (11,1%) пациента уровень ПТГ составил 686 пг/мл.
ВЫВОДЫ: таким образом, предложенный усовершенствованный способ оперативного лечения больных с ВГПТ на фоне 5 стадии ХБП в большинстве случаев позволяет получить стабильное снижение уровня
ПТГ при обеспечении необходимой безопасности вмешательства. Кроме того, предложенная методика
дает возможность выполнить малоинвазивную УЗ-контролируемую деструкцию перемещенной в предгортанные мышцы ОЩЖ при возможном рецидиве патологического процесса.