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Articles de revues sur le sujet « 9-10 yosh »

Auteur : Grafiati

Publié le 2 juin 2025

Mis à jour le 31 juillet 2025

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1

Nodira USMANOVA. "TURLI SPORT TAYYORGARLIGIGA EGA YOSH TENNISCHILARNING VESTIBULYAR APPARAT BARQARORLIGI DARAJASINI VA UNI RIVOJLANTIRUVCHI MASHQLAR SAMARASINI TADQIQ ETISH." UzMU xabarlari 1, no. 1.1 (2024): 175–79. http://dx.doi.org/10.69617/uzmu.v1i1.1.427.

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Maqolada tennis sport turi bilan shug‘ullanib kelayotgan 9-10 hamda 13-14 yoshli sportchilarning vestibulyar apparat barqarorligi darajalarini tadqiq etish natijalari yoritilgan. Vestibulyar apparat barqarorligini rivojlantiruvchi mashqlardan foydalanib, shug‘ullanuvchilarni vestibulyar ta`sirga nisbatan muvozanat saqlash imkoniyatlari test sinovlari yordamida aniqlangan. 9-10 va 13-14 yoshli tennischilarni vestibulyar apparat ta`sirga nisbatan qayt etilgan natijalar o`zaro taqqoslab tahlil etilgan.

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Attinger, Pascal, and Anna Glenn. "YOS 22, 49 = SEpM 7, X25." Nouvelles Assyriologiques Brèves et Utilitaires N.A.B.U. 95 (December 1, 2018): 152–55. https://doi.org/10.5281/zenodo.3554951.

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Parmi les textes intéressants figurant dans l’ouvrage récemment publié par le regretté W.W. Hallo, avec l’assistance de H. Torger Vedeler, Sumerian Literary and Historical Inscriptions (= YOS 22, 2018) se trouve un “nouveau duplicat” de SEpM 7, YOS 22, 49. Il est mentionné par Kleinerman dans son édition (2011: 227 avec n. 3), mais elle précise qu’elle n’a pas eu accès à la tablette (ibid.). La face et le revers 1 sq. contiennent l’ensemble de la composition. Après une double ligne e

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Aribjonova, Umida Abdurashitovna. "O'SMIRLIK YOSHI DAVRINING O'ZIGA XOS O'ZGARISHLARI VA PSIXОFIZIOLOGIK XUSUSIYATLARI". EURASIAN JOURNAL OF SOCIAL SCIENCES, PHILOSOPHY AND CULTURE 2, № 12 (2022): 4–9. https://doi.org/10.5281/zenodo.7273757.

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O’smirlik davri insonni bolalikdan - yoshlikka o’tuvchi va o’z navbatida boshqa davrlardan o’zining nisbatan keskinroq, murakkabroq kechishi bilan farqlanib turuvchi inson ontogenetik rivojlanishining eng xarakterli davrlaridan biridir. Bu davr psixologik pedagogik adabiyotlarda «O’tish davri», «og’ir davr», «inqiroz davri» kabi iboralar bilan ataladi. Bu davr taxminan bolalarning 5-8-sinflarda o’qish paytlariga to’g'ri keladi va 11-12 yoshdan 14-15 yoshgacha bo’lgan davr oraligida kechadi. Ayrim

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Chiu, Chih-Wei, Cheng-Ying Hsieh, Chih-Hao Yang, Jie-Heng Tsai, Shih-Yi Huang та Joen-Rong Sheu. "Yohimbine, an α2-Adrenoceptor Antagonist, Suppresses PDGF-BB-Stimulated Vascular Smooth Muscle Cell Proliferation by Downregulating the PLCγ1 Signaling Pathway". International Journal of Molecular Sciences 23, № 14 (2022): 8049. http://dx.doi.org/10.3390/ijms23148049.

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Yohimbine (YOH) has antiproliferative effects against breast cancer and pancreatic cancer; however, its effects on vascular proliferative diseases such as atherosclerosis remain unknown. Accordingly, we investigated the inhibitory mechanisms of YOH in vascular smooth muscle cells (VSMCs) stimulated by platelet-derived growth factor (PDGF)-BB, a major mitogenic factor in vascular diseases. YOH (5–20 μM) suppressed PDGF-BB-stimulated a mouse VSMC line (MOVAS-1 cell) proliferation without inducing cytotoxicity. YOH also exhibited antimigratory effects and downregulated matrix metalloproteinase-2

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Barber, Lauren E., Jasmine M. Miller-Kleinhenz, Maret L. Maliniak, Leah Moubadder, Jeffrey Switchenko, and Lauren E. McCullough. "Abstract PD1-03: Neighborhood deprivation and breast cancer mortality among Black and White women." Cancer Research 83, no. 5_Supplement (2023): PD1–03—PD1–03. http://dx.doi.org/10.1158/1538-7445.sabcs22-pd1-03.

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Abstract Background: Neighborhood deprivation is hypothesized as a potential driver of racial disparities in breast cancer mortality. However, research shows that neighborhood deprivation is associated with increased breast cancer mortality among White women, but has little to no association among Black women. No study has previously considered the intersections of race, social cohesion, or urban/rural status in the association between neighborhood deprivation and breast cancer mortality. Methods: Neighborhood deprivation was examined in relation to breast cancer mortality among 31,358 non-His

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Stanislaus, Surip. "PEDULI EKOLOGI ALA YESUS DAN PAULUS." LOGOS 17, no. 1 (2020): 1–15. http://dx.doi.org/10.54367/logos.v17i1.1036.

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Dalam Kitab Suci Perjanjian Baru sikap Yesus yang peduli ekologi dapat ditemukan dalam pewartaan-Nya tentang Kerajaan Allah. Visi-misi hidup Yesus adalah perjuangan demi terwujudnya Kerajaan Allah. Penginjil Yohanes menegaskan bahwa Yesus datang untuk melakukan kehendak Bapa-Nya yang sejak awal mula penciptaan alam semesta menghendaki keharmonian dan keutuhan hidup seluruh ciptaan-Nya, sehingga semuanya diciptakan baik adanya bahkan amat baik (Yoh 5:19,30; 8:26,28,38; Kej 1:10,12,18,21,25,31). Berkaitan dengan keutuhan ciptaan dan harmoni alam, Yesus mewartakan Kerajaan Allah itu lewat perumpa

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Yuan, Yuan, Colt A. Egelston, Weihua Guo, et al. "Abstract OT2-01-06: Phase II trial of palbociclib plus endocrine therapy followed by combination of pembrolizumab, palbociclib and endocrine therapy in patients with hormone receptor positive metastatic breast cancer." Cancer Research 83, no. 5_Supplement (2023): OT2–01–06—OT2–01–06. http://dx.doi.org/10.1158/1538-7445.sabcs22-ot2-01-06.

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Abstract Background: The combination of CDK4/6 inhibitors (CDK4/6i) and endocrine therapy (ET) is standard-of-care for patients with hormone receptor positive (HR+) HER2- metastatic breast cancer (MBC). Immune modulatory effects of CDK4/6i are well documented preclinically but poorly understood in the clinical setting. Our previous study combining letrozole, palbociclib and pembrolizumab in patients with HR+ MBC (NCT02778685) showed a promising complete response rate of 31%. Dynamic changes in peripheral blood mononuclear cell (PBMC) subpopulations indicated that palbociclib may increase CD8+

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Lee, Jin Sun, Susan Yost, Yujie Cui, et al. "Abstract P5-13-35: Mechanisms of CDK4/6 inhibitor resistance in hormone receptor positive metastatic breast cancer: Single institution retrospective analysis." Cancer Research 82, no. 4_Supplement (2022): P5–13–35—P5–13–35. http://dx.doi.org/10.1158/1538-7445.sabcs21-p5-13-35.

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Abstract Background: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) are the standard of care for hormone receptor positive (HR+) metastatic breast cancer (MBC). Mechanisms of intrinsic and acquired resistances have been proposed but are poorly understood in the real-world setting. The current study aims to study the association of genomic biomarkers and CDK 4/6i resistance mechanisms utilizing genomic data acquired through routine clinical practice. Methods: Tumor genomic data from patients with HR+ MBC who received FDA-approved CDK4/6i (palbociclib, ribociclib, and abemaciclib) were obtaine

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Supriyadi, Endang, and Maya Sofiana. "Strategi Pengembangan Sistem Informasi Berbasis E-KTP di Kantor Kelurahan Galur (Studi Kasus Kelurahan Galur Kota Jakarta Pusat)." Jurnal Sistem Informasi 10, no. 2 (2021): 69–74. http://dx.doi.org/10.51998/jsi.v10i2.421.

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Intisari— Sistem Informasi adalah suatu sistem yang berada dalam suatu organisasi yang mengelola kebutuhan pengolahan transaksi harian yang mendukung operasi dan juga dalam kegiatan strategi dalam suatu organisasi dengan menyediakan laporan-laporan yang diperlukan. Seiring dengan perkembangan teknologi informasi dan komunikasi yang semakin pesat saat ini sangatlah memungkinkan masyarakat untuk bisa mengakses informasi apa saja yang mereka butuhkan dalam kehidupan sehari-hari, seolah-olah tidak ada batasannya. Salah satu program yang mulai diterapkan sekarang ini oleh Kementrian Dalam Negeri Re

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Williams, Courtney, Jessica M. Shuey, Joud El Dick, et al. "Socioeconomic- and insurance-based inequities in Oncotype DX testing and score-guided treatment." Journal of Clinical Oncology 43, no. 16_suppl (2025): 1589. https://doi.org/10.1200/jco.2025.43.16_suppl.1589.

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1589 Background: Personalized approaches to breast cancer treatment are increasingly guided by expensive, lab-based genomic testing like Oncotype DX (ODX) Breast Recurrence Score Test.Little is known about how socioeconomic and insurance status may affect utilization of ODX testing and subsequent ODX score-guided treatment. Methods: This retrospective cohort study included women diagnosed with an early-stage, HR+/HER2- breast cancer from 2011-2023 within the nationwide Flatiron Health electronic health record-derived deidentified database. Socioeconomic status was measured by the Yost index, a

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Jain, Nayan, Zeguo Zhao, Richard Koche, et al. "Abstract 5583: SUV39H1 disruption enhances the persistence and anti-tumor efficacy of CD28-costimulated human CAR T cells." Cancer Research 82, no. 12_Supplement (2022): 5583. http://dx.doi.org/10.1158/1538-7445.am2022-5583.

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Abstract Retrovirally encoded CD19-specific CARs that incorporate CD28 and CD3z signaling motifs (Rv-1928z) have induced remarkable responses in patients with refractory leukemia and lymphoma. These CARs induce a strong effector differentiation program in T cells that can limit their persistence and result in T cell dysfunction. This induction of terminal effector differentiation is accompanied by transcriptional and epigenetic changes resulting in induction of effector transcriptional factors, inhibitory receptors, and suppression of memory associated genes. In this study, we examine the effe

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Batra, Akshee, Andrew Sparks, Rohit Singh, Atulya Aman Khosla, Neil Zakai, and Diego Adrianzen Herrera. "Metabolic Syndrome Among Patients with Myelodysplastic Syndrome: A Population Analysis." Blood 142, Supplement 1 (2023): 3805. http://dx.doi.org/10.1182/blood-2023-187472.

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Introduction: Metabolic syndrome (MS) comprises a cluster of cardiovascular risk factors, including central obesity, dysglycemia, elevated blood pressure (BP), increased triglyceride levels (HyperTG), and low HDL cholesterol levels. Epidemiologic and clinical data suggest that MS may be an important etiologic factor in the progression of certain cancer types. These studies have excluded patients with myelodysplastic syndromes (MDS), but MS may be relevant in these patients owing to the link between cardiovascular disease and MDS derived from clonal hematopoiesis. We conducted a population-base

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Svoboda, Jakub, Philippe Armand, Fiona Taylor, et al. "Health-Related Quality-of-Life Outcomes in Patients with Classical Hodgkin Lymphoma: A Prospective, Observational Study in US Oncology Practices." Blood 134, Supplement_1 (2019): 2192. http://dx.doi.org/10.1182/blood-2019-123980.

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Introduction: Classical Hodgkin lymphoma (cHL) is highly curable with front-line multi-agent chemotherapy with or without radiotherapy. The treatment landscape is rapidly evolving, with a continued focus on optimizing available therapies in order to improve outcomes and minimize toxicity. Randomized controlled trials provide valuable insights into new treatments and outcomes; however, real-world data describing treatment effectiveness, safety, and health-related quality of life (HRQoL) are limited. This analysis was conducted to understand patient-reported outcomes (PROs) in patients who were

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Egelston, Colt A., Weihua Guo, Susan E. Yost, et al. "Abstract OT2-08-03: Immunogenicity of pembrolizumab and doxorubicin in a phase I trial for patients with metastatic triple negative breast cancer." Cancer Research 83, no. 5_Supplement (2023): OT2–08–03—OT2–08–03. http://dx.doi.org/10.1158/1538-7445.sabcs22-ot2-08-03.

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Abstract Background: Combination of immune checkpoint inhibitor pembrolizumab and chemotherapy are standard of care therapy for patients with programmed death-ligand 1 positive (PD-L1+) metastatic triple negative breast cancer (mTNBC). However, a greater understanding of how immune checkpoint inhibitors and chemotherapies synergize to yield anti-tumor T cell responses is needed. The current phase I study evaluated the immunogenicity of doxorubicin plus pembrolizumab in patients with mTNBC. Patients and Methods: Patients with mTNBC, no prior anthracycline use, and 0-2 lines of prior systemic ch

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Winestone, Lena E., Sumit Gupta, Jeannette Sample, et al. "Distance to Care Predicts Clinical Trial Enrollment on COG ALL Clinical Trials: A Report from the Children's Oncology Group." Blood 142, Supplement 1 (2023): 2392. http://dx.doi.org/10.1182/blood-2023-182477.

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Introduction: Equitable participation in clinical trials for all populations is essential to ensure the generalizability of clinical trial results. Historical data suggest that the majority of pediatric patients are enrolled on a trial when treated at a cooperative group institution and minoritized patients are proportionally represented. We proposed to evaluate clinical trial enrollment on Children's Oncology Group (COG) acute lymphoblastic leukemia (ALL) studies to determine if among those who participate in registry studies, there are disparities in participation in therapeutic clinical tri

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McKinnell, Zoe, Mustafa Hammudi, Daniel Tuerff, et al. "Real world outcomes of veterans 18-45 years old with acute lymphocytic leukemia." Journal of Clinical Oncology 41, no. 16_suppl (2023): e18852-e18852. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e18852.

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e18852 Background: Age is a strong prognostic factor in acute lymphocytic leukemia (ALL), with children doing better than adults with the same disease. One hypothesis for this age-based disparity is differences in treatment regimens. Current NCCN guidelines say it is acceptable to treat young adult patients with either pediatric or adult regimens. We conducted a retrospective study of all veterans with ALL diagnosed between the ages of 18-45 since the year 2000 to evaluate the effect of different treatment regimens on overall survival. We also evaluated other disparities that exist among young

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Heymach, John, Frans Opdam, Minal Barve, et al. "Abstract CT203: Updated data from the Phase I Beamion Lung 1 trial of the HER2 tyrosine kinase inhibitor (TKI), BI 1810631, as monotherapy in patients (pts) with advanced/metastatic solid tumors with HER2 aberrations." Cancer Research 83, no. 8_Supplement (2023): CT203. http://dx.doi.org/10.1158/1538-7445.am2023-ct203.

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Abstract Background: There is an unmet need for effective TKIs against HER2 mutations in solid tumors, particularly in NSCLC. BI 1810631 is a HER2-selective TKI that covalently binds to both wild-type and mutated HER2 receptors, including exon 20 insertions, whilst sparing EGFR signaling. This ongoing Phase Ia/Ib, open-label, non-randomized study aims to determine the safety, MTD, PK, pharmacodynamics and preliminary efficacy of BI 1810631 in pts with HER2 aberration-positive solid tumors (NCT04886804). Here, we present interim results of Phase Ia. Materials and Methods: In Phase Ia, pts with

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Crew, Katherine D., Garnet Anderson, Kathryn Arnold, et al. "Abstract OT1-15-01: SWOG 1904: Cluster-randomized controlled trial of patient and provider decision support to increase chemoprevention informed choice among women with atypical hyperplasia or lobular carcinoma in situ (MiCHOICE)." Cancer Research 83, no. 5_Supplement (2023): OT1–15–01—OT1–15–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-ot1-15-01.

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Abstract Background: Despite evidence of substantial breast cancer risk reduction, few high-risk women adopt chemopreventive medications such as selective estrogen receptor modulators (SERMs) or aromatase inhibitors (AIs). Women with benign breast disease, such as atypical hyperplasia (AH) or lobular carcinoma in situ (LCIS), have an increased risk of developing breast cancer and derive a greater benefit from antiestrogens compared to other high-risk women. Reasons for low uptake of chemoprevention include insufficient patient and clinician knowledge about antiestrogens, time constraints durin

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Nyalakonda, Suraj, Madeline Williams, Roxanna Fouladi, et al. "Clinical Impact of Serum Ferritin Levels and EBV-Positivity in Nodal T-Cell Lymphomas." Blood 144, Supplement 1 (2024): 6415. https://doi.org/10.1182/blood-2024-209306.

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Introduction Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), Angioimmunoblastic T-cell Lymphoma (AITL) and Anaplastic Large Cell Lymphoma (ALCL), ALK-negative are common nodal T-cell lymphomas (TCL). Prognosis is dismal, with high rates (20-25%) of primary progression, 3-year progression-free survival (PFS) of &lt;30%, and median survival at first relapse &lt;6 months (Ellin et al. Blood 2014). The prognostic impact of a biomarker of hemophagocytic lymphohistiocytosis (HLH) in TCL, ferritin, is being explored (Yoh et al. CLML 2014). Moreover, EBV-positivity is associated

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Idrobo, Henry, Denisse Castro, Lorena Fiad, et al. "Clinico-Epidemiological Features of Elderly Patients with Peripheral T-Cell Lymphoma Not Otherwise Specified: A Study from the Grupo De Estudio Latinoamericano De Linfoproliferativos (GELL)." Blood 138, Supplement 1 (2021): 2468. http://dx.doi.org/10.1182/blood-2021-153849.

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Abstract Introduction: Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is the most common PTCL subtype, accounting for approximately 25% of all PTCL cases. The median age at diagnosis is 60 years and is more prevalent among males. Currently, most epidemiological data on T- and NK-cell lymphomas come from developed countries. Thus, very few data are available regarding this condition in Latin American countries, especially in those aged 60 years and older. The Latin American Group of Lymphoproliferative Disorders (GELL) has previously reported on the impact of serum albumin level

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Chrisnawati, Chrisnawati, Subarjo Subarjo, Sapariah Anggraini, and Anastasia Maratning. "GAMBARAN PENGETAHUAN IBU TENTANG KEJADIAN IKUTAN PASCA IMUNISASI (KIPI) DPT-HIB DI PUSKESMAS ASAM-ASAM TAHUN 2021." JURNAL KEPERAWATAN SUAKA INSAN (JKSI) 7, no. 1 (2022): 1–6. http://dx.doi.org/10.51143/jksi.v7i1.292.

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Latar Belakang : KIPI merupakan suatu reaksi simpang yang dikenal sebagai kejadian ikutan pasca imunisasi berhubungan dengan kejadian medis yang dapat menimbulkan berbagai efek samping akibat imunisasi. Data kasus KIPI tidak serius berupa demam, bengkak dan merah bekas suntikan akibat vaksin DPT-Hib di wilayah Kabupaten tanah laut sebanyak 219 kasus dan di Puskesmas Asam-Asam sebanyak 47 kasus (Dinas Kesehatan Tanah Laut,2019). Dampak KIPI akan menimbulkan stigma/ trauma dari ibu untuk ikut dalam program imunisasi. Oleh karena itu, sangat penting peran dan pengetahuan ibu untuk dapat mengelola

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Akbar, Jailudin Muhammad, Riky Hamdani, and Dewi Puspitasari. "THE RELATIONSHIP OF MOTIVATION ON THE INTEREST OF THE COMMUNITY VISITING THE DENTIST DURING THE COVID-19 PANDEMIC IN SUNGAI MIAI VILLAGE." Dentino : Jurnal Kedokteran Gigi 8, no. 1 (2023): 35. http://dx.doi.org/10.20527/dentino.v8i1.16075.

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ABSTRACTBackground: Corona Virus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov2). The COVID-19 pandemic severely limits the community environment, one of which is the limitation of dental and oral health services. The wide spread of the COVID-19 virus has caused many people to feel afraid to have their teeth checked in the midst of a pandemic, thus affecting the motivation and interest of the public to visit the dentist's practice. Objective: This study aims to determine the relationship between motivation and public intere

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Yuldasheva, Gulchehra Akmalovna Ixtisoslashtirilgan ta'lim muassasalari agentligi tizimidagi Kogon shahar ixtisoslashtirilgan maktabi 8.-sinf o'quvchisi. "YURAKNING TUZILISHI VA FUNKSIYASI." Innovative technologies in construction Scientific Journal (ITC) 2, no. 2 (2023): 3–8. https://doi.org/10.5281/zenodo.8163749.

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<strong><em>ANNOTASIYA: </em></strong><em>Ushbu maqolada yurak a’zosining tuzilishi, uning tarkibiy qismlari va funksiyasi yoritilgan. Shuningdek, maqolada 8-sinf Biologiya (odam va uning salomatligi) darsligida berilgan yurak tuzilishi mavzusini animatsion dasturiy vositalar orqali o‘qitish hamda o‘quvchilarga mavzuni tushunarli tarzda etkazish metodikasini takomillashtirish. </em><em>Maqolada yurakning tuzilishini, uning funksiyasini tushuntirishda 3D animatsion</em> <em>video roliklardan, virtual laboratoriyalardan foydalanishning ahamiyati keltirilgan. </em> <strong><em>K

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Raxmatov, Shoxrux, and G.Xolboyeva. "9-10 YOSH O`QUVCHILARNING GIMNASTIKA MASHG`ULOTLARIDA EGILUVCHANLIK SIFATINI RIVOJLANTIRISH USULLARI." Research Focus International Scientific Journal 4, no. 5 (2025). https://doi.org/10.5281/zenodo.15512165.

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<strong>9-10 YOSH O`QUVCHILARNING GIMNASTIKA MASHG`ULOTLARIDA EGILUVCHANLIK SIFATINI RIVOJLANTIRISH USULLARI</strong> <strong>https://doi.org/10.5281/zenodo.15512165</strong> <strong>Raxmatov Shoxrux</strong> O‘z-FinPI magistri <strong>G.Xolboyeva</strong> O‘z-FinPI dotsenti <strong>Annotatsiya:</strong> Ushbu maqolada 9-10 yoshdagi oquvchilarda gimnastika mashgulotlari orqali egiluvchanlik sifatini rivojlantirishning muhimligi va samaradorligi korib chiqilgan. Maqolada egiluvchanlikning rivojlanishi uchun mos mashqlar, texnikalar va usullar tasvirlangan. Shuningdek, egiluvchanlikn

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Sh.S., Xojiyev. "YOSH XOKKEYCHILARNING HARAKAT TAYYORGARLIGINI SHAKLLANTIRISHDA 3D VA VR TEXNOLOGIYALARINI QO'LLASHNING METODIK ASOSLARI." May 4, 2025. https://doi.org/10.5281/zenodo.15338287.

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maqolada yosh xokkeychilarni (9-10 yosh) tayyorlash tizimiga 3D va VR texnologiyalarini joriy etishning nazariy va amaliy jihatlari ochib berilgan. 3D MA yordamida laboratoriya tahlilini, VR modullari (NHL Sense Arena, Hockey VR, Pick-up League Hockey) va an'anaviy muz tayyorgarligini birlashtirgan eksperimental metodikani ishlab chiqish va sinovdan o'tkazish bosqichlari tavsiflangan. Tajriba ("Snejniy Bars" XK, n=15) va nazorat ("Binokor-2" XK, n=15) guruhlarining qiyosiy tahlili natijalari keltirilgan. 3D, 2D va VR test ma'lumotlari asosida yondashuvning samaradorligi asoslangan.

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Ibodova, Malika. "SHAXS AXLOQIY TARBIYASINI SHAKLLANTIRISHDA MILLIY QADRIYATLARNING O'RNI Ibodova Malika Qarshi davlat universiteti Lingvistika:o'zbek tili yo'nalishi magistranti ANNOTATSIYA.Ushbu maqolada shaxs axloqiy tarbiyasini shakllantirishda milliy qadriyatlarning o'rni masalalari,yurtimizda yosh avlodni tarbiyalashda amalga oshirilayotgan ishlar ko'rib chiqilgan. Kalit so'zlar: axloqiy tarbiya, ma'naviy meros, ma'naviy-axloqiy qadriyatlar, axloq normalari, shaxs barkamolligi, axloqiy me'yorlar, axloqiy ong, milliy qadriyat. Shaxs dunyoqarashining shakllanishida ma'naviy-axloqiy tarbiya ham muhim o'ringa ega bo'lib, uni samarali tashkil etish o'quvchida ma'naviy-axloqiy ongni shakllantirishga yordam beradi. Axloqiy tarbiya muayyan jamiyat tomonidan tan olingan va rioya qilinishi zarur bo'lgan xulq-atvor qoidalari, mezonlarini o'quvchilar ongiga singdirish ularda axloqiy ong, axloqiy faoliyat ko'nikmalari hamda axloqiy madaniyatni shakllantirishga yo'naltirilgan pedagogik jarayon bo'lib, ijtimoiy tarbiyaning muhim tarkibiy qismlaridan biri sanaladi. Axloqiy ong - ijtimoiy ong shakllaridan biri bo'lib, jamiyat tomonidan tan olingan va rioya qilinishi zarur bo'lgan xulq-atvor qoidalari, mezonlari, shuningdek, milliy istiqlol g'oyasining o'quvchilar ongida aks etishidir. Axloqiy ong, axloqiy faoliyat ko'nikmalari hamda axloqiy madaniyat ta'lim-tarbiya jarayonida yo'lga qo'yilayotgan axloqiy, ijtimoiy-g'oyaviy, iqtisodiy, huquqiy, estetik va ekologik mavzulardagi suhbat, bahs-munozara, debatlar xalq xo'jaligining turli sohalarida fidokorona mehnat qilayotgan, ilm-fan, madaniyat, ishlab chiqarish hamda sport sohalarida yuksak darajadagi muvaffaqiyatlarni qo'lga kirish bilan O'zbekiston Respublikasi nomini jahonga mashhur qilayotgan, uning obro'-e'tiborining oshishiga o'zining munosib hissasini qo'shayotgan shaxslar hayoti va faoliyat to'g'risidagi ma'lumotlardan samarali foydalanish, vatanparvarlik namunalarini ko'rsatgan, xalq qahramonlari namunasida shakllantiriladi. Axloqiy tarbiya o'quvchilarda dunyoqarashni shakllantirishda ham muhim ahamiyatga ega bo'lib, uni samarali tashkil etishda ong, his-tuyg'u hamda xulq-atvor birligiga erishish maqsadga muvofiqdir. Zero, ular birligida ma'lum kamchiliklarning yuzaga kelishi ham o'quvchilarning komil shaxs bo'lib kamol topishlariga salbiy ta'sir ko'rsatadi. Dunyoqarash tabiat, jamiyat, inson tafakkuri hamda shaxs faoliyati mazmunining rivojlanib borishini belgilab beruvchi dialektik qarashlar va e'tiqodlar tizimidir. O'quvchilarni ma'naviy-axloqiy jihatdan tarbiyalashda milliy istiqlol g'oyasi va mafkurasi asoslari tayanch omillar sifatida namoyon bo'ladi.Yosh avlod tarbiyasida milliy qadriyatlardan foydalanishning ahamiyati va o'rni katta. Ma'naviy qadriyatlar va milliy o'zlikni anglashning tiklanishi. Biron -bir jamiyat imkoniyatlarini, odamlar ongida ma'naviy va axloqiy qadriyatlarni rivojlantirmay hamda mustahkamlamay turib o'z istiqbolini tasavvur eta olmaydi. Ming yillar mobaynida Markaziy Osiyo g'oyat xilma-xil dinlar, madaniyatlar va turmush tarzlari tutashgan va tinch totuv yashagan markaz bo'lib kelgan. Etnik sabr- toqat, bag'rikenglik hayot bo'ronlaridan omon qolish va rivojlanish uchun zarur tabiiy me'yorlarga aylandi. Hatto bu hududlarni bosib olganlar ham qimmatbaho an'analarini, shu hududda mavjud bo'lgan davlatchilik an'analarini avaylab qabul qilganlar. Oila qadriyatlari va qon- qarindoshlik munosabatlaring qayta tiklanishi o'z umrini yashab bo'layotgan oila- urug'. Har bir xalqning o'ziga yarasha urf-odatlari, marosimlari bo'ladi. Agar biz dunyo xalqlarining hayotiga nazar tashlasak bir-biriga o'xshamagan, turli-tuman marosimlarni ko'ramiz. Marosimlar jamiyat, xalq va shaxs hayoti-faoliyatidagi muhim o'zgarishlar, ijtimoiy ahamiyatga molik voqea-hodisalar bilan bog'liq bo'lib, ular ibrat orqali tarbiyalash, ruhiy-estetik ta'sir ko'rsatish vazifasini bajaradi. Marosimlarda milliy,diniy urf-odatlar va rasm-rusumlar ham o'z ifodasini topadi. O'zbek xalqining paydo bo'lishi tarixi qanchalik uzoqqa borib taqalsa, uning milliy an'analari, urf odatlari, marosimlari ham shunchalik teran tarixiy ildizga ega. Ular xalqning ma'naviy ehtiyojlari zaminida paydo bo'lib, shakllanib, sayqallanib o'z mazmunida shu xalqning orzu-o'ylari, istaklari, turmush tarzi, axloq normalarini mujassam etadi. Shuning uchun ham har bir xalq, millat, elat ularni ko'z qorachig'iday avaylab-asrashi, taraqqiy ettirishi, kelgusi avlodlarga ma'naviy qadriyat sifatida etkazmog'i lozim. Darhaqiqat, an'analar, urf-odatlar, marosim va bayramlar xalqning, millatning ma'naviyati, qadriyatlarini ajralmas qismidir. Milliy qadriyatlar xalqning kundalik hayoti va turmush tarzida o'ziga xos mezon vazifasini o'taydi. Ushbu qadriyatlar vositasida turli hodisa va holatlarga, yangi paydo bo'layotgan faoliyat turlari va rasm-rusumlarga baho beriladi. Yosh avlodning hayotiy mo'ljallari, «zamona qahramoni» haqidagi tasavvurlari ham manaviy qadriyatlardan kelib chiqib shakllanadi. Xulosa qilib aytganda, asrlar davomida avloddan avlodga o'tib kelgan milliy manaviy qadriyatlar milliy g'oyaga manaviy zamin, negiz bo'lib xizmat qilmoqsa. Unga xalq, millat, jamiyat amal qilish uchun kuchli, qudratli, tasirli milliy mafkura kerak. Milliy manaviy qadriyatlarning har bir tarkibiy qismi xalqning mustaqilligini mustahkamlash va kelajagini taminlashda muhim ahamiyatga ega. Xar tomonlama rivojlangan, gormonik rivojlangan, milliy qadriyatlarimizni e'zozlaydigan barkamol avlod tarbiyasida mahalla, ota-onalar va pedagoglarning o'zaro xamjixatligi asosiy omillardan xisoblanadi. Milliy qadriyatlarimizni e'zozlaydigan, o'z hayot faoliyatida doimo millat g'ururi bilan ish olib boradigan yoshlarning tarbiyalanishi millat kelajagini, rivojlanishini ta'minlaydi. Foydalanilgan adabiyotlar ro'yxati: 1. Komilova, N. A. (2022, June). COMPARATIVE ANALYSIS OF LEXICAL VERBALIZERS OF THE CONCEPT "GENDER" IN UZBEK AND ENGLISH LANGUAGES. In International Scientific and Current Research Conferences (pp. 103-106). 2. Komilova, N. A. Comparative Analysis of "Gender" Concept and Issues of Gender Field in English and Uzbek Languages. 3. Do'smatov, H. (2022, June). O 'ZBEK TILIDA SO 'Z TURKUMLARI TASNIFI MASALALARI. In INTERNATIONAL CONFERENCE: PROBLEMS AND SCIENTIFIC SOLUTIONS. (Vol. 1, No. 1, pp. 108-113). 4. Abdilkadimovna, K. N. (2021). Comparative And Linguocultural Analysis Of The Concept" Gender" In Uzbek And English Languages. The American Journal of Social Science and Education Innovations, 3(06), 112-117. 5. Мирзааҳмедович, Х. Ғ., & Комилова, Н. А. (2021). ИНГЛИЗ ВА ЎЗБЕК ТИЛЛАРИДА ГЕНДЕР КОНЦЕПТУАЛ СЕМАНТИКАСИ ВЕРБАЛИЗАТОРЛАРИ НОМИНАТИВ ТУРЛАРИНИНГ ЛИНГВОКУЛЬТУРОЛОГИК ХУСУСИЯТЛАРИ. МЕЖДУНАРОДНЫЙ ЖУРНАЛ ИСКУССТВО СЛОВА, 4(6). 6. qizi, S. G. N. ., & qizi, R. M. A. . (2022). Word Categories in English. Middle European Scientific Bulletin, 26, 14-16. Retrieved from https://cejsr.academicjournal.io/index.php/journal/article/view/1431 7. Shodieva, G. N. Q., & Rakhmonova, M. A. Q. (2021). INFORMATION PERIOD CHANGE OF PEOPLE'S OUTLOOK, NEGATIVE AND POSITIVE IMPACT OF THE INTERNET. Scientific progress, 2(8), 563-566. 8. Do'smatov, D., & qizi Shodiyeva, G. N. (2022, May). O 'ZBEK TILSHUNOSLIGIDA SO 'ZLARNI TURKUMLARGA AJRATISH TAMOYILLARI. In INTERNATIONAL CONFERENCES ON LEARNING AND TEACHING (Vol. 1, No. 8, pp. 770-774). 9. Shodiyeva, G. N. Q. (2022). MATN GRAMMATIKASINING ASOSIY MUAMMOLARI. Academic research in educational sciences, 3(NUU Conference 2), 1173-1176. 10. Kizi, S. G. N., & Tolibovna, S. A. (2022). Semantic features and new methods of non-standard English. Ta'lim fidoyilari, 24(17), 2-272. 11. Najmiddinovna, R. Z., & Najmiddinovna, R. K. (2022). INNOVATIVE APPROACHES IN FOREIGN LANGUAGE TEACHING. INTERNATIONAL JOURNAL OF SOCIAL SCIENCE & INTERDISCIPLINARY RESEARCH ISSN: 2277-3630 Impact factor: 7.429, 11(05), 19-21." 10 липня 2022. https://doi.org/10.5281/zenodo.6815841.

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Ochoa Allemant, Pedro, Evelyn Obregón Julca, Fiorella Nuñez del Prado Zora Carbajal, María Cristina Ojeda Nieto, and Marcial Anaya Pajuelo. "Utilidad de la Escala Observacional de Yale como Método de Triaje para Detectar Enfermedad Grave en Lactantes Febriles." Revista Peruana de Pediatría, December 31, 2014, 67–77. http://dx.doi.org/10.61651/rped.2014v67n2p67-77.

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    Objetivos: Evaluar la utilidad de la Escala Observacional de Yale (YOS) como método triaje para detectar enfermedad grave en lactantes febriles. Materiales y Métodos: Estudio de tipo observacional, prospectivo de corte longitudinal donde se aplicó la YOS a los pacientes febriles de 3 a 24 meses que acudieron a la Emergencia Pediátrica del Hospital Nacional Arzobispo Loayza del 13 de abril al 6 de junio del 2012 antes de la atención médica. Los pacientes hospitalizados fueron seguidos hasta el alta y la confirmación del diagnóstico. Los ambulatorios fue

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Gray, Darryl T. "Abstract W P292: Variable Frequencies, Outcomes and Costs Argue for Separate Tracking of Ischemic Strokes (ISs), Subarachnoid Hemorrhages (SAHs) and Other Hemorrhagic Strokes (OHSs)." Stroke 46, suppl_1 (2015). http://dx.doi.org/10.1161/str.46.suppl_1.wp292.

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Introduction: While cause and treatment vary for ISs, SAHs and OHSs, their results are often combined in reported statistics. Hypothesis: ISs, SAHs and OHSs differ in frequency and outcomes. Methods: ICD-9-CM principal discharge (D/C) diagnosis codes of 430 (SAH), 431-432 (OHS) and 433-434 (IS) were used to obtain US nationwide estimates of stroke frequency and outcomes for 2006-2012 from HCUPnet, the on-line query system of the Healthcare Cost and Utilization Project (HCUP). HCUP's sampling frame captured ~90% of D/Cs from non-Federal acute care hospitals for 2006, and >95% of such D/Cs as

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Rory, Crean, and Kamerlin Lynn. "MD and EVB parameters for the manuscript titled: Sequence – Dynamics – Function Relationships in Protein Tyrosine Phosphatases." June 16, 2023. https://doi.org/10.5281/zenodo.7892058.

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This repo is split into the following subfolders: ######### MD_Simulations: ######### The starting structures used to perform all MD simulations in our paper. Alongside the input files used to run the MD simulations. Simulations were performed with Amber and the final step used to prepare each structure was with tleap (part of amber tools). The parameters for the phosphoenzyme intermediate residue are provided alongside an example tleap script that was used to prepare each structure.  Please see the paper for details on how each structure was prepared.  The input files have the follo

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"Band of Brothers. Produced by Tom Hanks and Stephen Spielberg; directed by Phil Alden Robinson (part 1, Currahee), Richard Loncraine (part 2, Day of Days), Mikael Salomon (part 3, Carentan, and part 10, Points), David Nutter (part 4, Replacements), Tom Hanks (part 5, Crossroads), David Leland (part 6, Bastogne), David Frankel (part 7, The Breaking Point, and part 9, Why We Fight), and Tony To (part 8, The Patrol); screenplay by Erik Jendresen and Tom Hanks (part 1), John Orloff (part 2), E. Max Frye (part 3), Graham Yost and Bruce C. McKenna (part 4), Erik Jendresen (part 5), Bruce C. McKenna (part 6), Graham Yost (part 7), Erik Bork and Bruce C. McKenna (part 8), John Orloff (part 9), and Erik Jendresen and Erik Bork (part 10). 2001, color; 500 minutes. Distributed by Home Box Office (HBO)." American Historical Review, June 2002. http://dx.doi.org/10.1086/ahr/107.3.991.

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Thi Hien, Nguyen, Do Thi Cam Nhung, Nguyen Phu Hung, Bui Phuong Thuan, and Nguyen Quang Huy. "Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents." VNU Journal of Science: Natural Sciences and Technology 35, no. 3 (2019). http://dx.doi.org/10.25073/2588-1140/vnunst.4893.

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Benzene (B), toluene (T), ethylbenzene (E) and xylene (X) are used commonly in paint industry, so workers who are a high risk of exposure to organic solvent (VOCs). CYP2E1 gene encodes CYP2E1 which plays an important role in the metabolism and bio-activation of volatile organic compounds. When workers expose to VOCs, their body will have a mechanism to metabolize the toxic. The enhancement of mRNA expression of CYP2E1 is a very sensitive and accurate biological marker, which is the basis for the next study to propose the level of mRNA expression of CYP2E1 gene as a human biological indicator t

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sprotocols. "Endodcytic labelling of visceral endoderm of mouse perigastrulation embryos." January 8, 2015. https://doi.org/10.5281/zenodo.13840.

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Authors: Yoh Wada, Minako Aoyama, Ge-Hong Sun-Wada, Nobuyuki Kawamura & Hiroyuki Tabata ### Abstract In this protocol we describe methods for observation endocytic activity in the mouse embryos. The methods are optimised for mouse embryos at E5.5~E7.2 pregastrulation/gastrulation stages. We optimise three different experimental schemes for tracing the embryonic endocytosis. In utero labelling scheme, an endocytic tracer is introduced into circulation of a pregnant mother to follow bulk uptake of fluid phase endocytosis. Rodent embryos are known to internalise maternal immunoglobulins, thus

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"Buchbesprechungen." Zeitschrift für Historische Forschung 46, no. 4 (2019): 641–754. http://dx.doi.org/10.3790/zhf.46.4.641.

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Rexroth, Frank / Teresa Schröder-Stapper (Hrsg.), Experten, Wissen, Symbole. Performanz und Medialität vormoderner Wissenskulturen (Historische Zeitschrift. Beihefte (Neue Folge), 71), Berlin / Boston 2018, de Gruyter Oldenbourg, 336 S. / Abb., € 89,95. (Lisa Dannenberg-Markel, Aachen) Enenkel, Karl A. E. / Christine Göttler (Hrsg.), Solitudo. Spaces, Places, and Times of Solitude in Late Medieval and Early Modern Cultures (Intersections, 56), Leiden / Boston 2018, Brill, XXXIV u. 568 S. / Abb., € 165,00. (Mirko Breitenstein, Dresden / Leipzig) Tracy, Larissa (Hg.), Medieval and Early Modern M

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