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1

Neeraj, Kumar Tomar, Zulfeqarr Fahed, and Sharma M.C. "Softly pgD- Normal Spaces." MATHEMATICS EDUCATION LIX, no. 1, March 2025 (2025): 1–17. https://doi.org/10.5281/zenodo.15551191.

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&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <em>&nbsp; &nbsp; The aim of this paper is to introduce a new class of softly normal called softly pgD- normality by using pgD-open sets and obtained several properties of such a space. We discuss many properties of this new space and we give some properties that connect this new spaces with some other topological spaces, also we present some examples and counter examples that show the relationships between softly pgD- normal spaces and some other topological spaces, also we introduced the concept of pgD-normal, almost pgD-normal, quasi pgD-normal, mildly pgD
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Olszak, Zbigniew, and Radu Roşca. "Normal locally conformal almost cosymplectic manifolds." Publicationes Mathematicae Debrecen 39, no. 3-4 (2022): 315–23. http://dx.doi.org/10.5486/pmd.1991.39.3-4.12.

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De, Uday Chand, Mine Turan, Ahmet Yildiz, and Avik De. "Ricci solitons and gradient Ricci solitons on $3$-dimensional normal almost contact metric manifolds." Publicationes Mathematicae Debrecen 80, no. 1-2 (2012): 127–42. http://dx.doi.org/10.5486/pmd.2012.4947.

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Yang, Moo Sheng, Yue Liang Chen, Yu Quan Bi, and Wen Hao Jiang. "Prediction of Fretting Fatigue Life of Aluminum Alloy LY12CZ." Advanced Materials Research 146-147 (October 2010): 252–56. http://dx.doi.org/10.4028/www.scientific.net/amr.146-147.252.

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Stress in the interface of contacts was calculated applying finite element software/ABAQUS, with which the Ruiz fretting damage parameter was obtained and the location for crack formation was found. A new model for predicting fretting fatigue life has been presented based on friction work. The rationality and effectiveness of the model were validated according to the contrast of experiment life and predicting life. At last influence factor on fretting fatigue life of aerial aluminum alloy LY12CZ was investigated with the model. The results revealed that fretting fatigue life decreased monotono
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Rahmawati, Ima, and Kend Ramadio Rimba Syah Yogha. "GRADE ANKLE BRACHIAL INDEX (ABI) AS A PREDICTOR OF PERIPHERAL ARTERY DISEASE (PAD) IN MELLITUS PATIENTS." INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) 9, no. 1 (2025): 14–21. https://doi.org/10.29082/ijnms/2025/vol9/iss1/682.

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Peripheral Artery Disease (PAD) often occurs in diabetes mellitus patients. PAD can be detected early by measuring the Ankle Brachial Index (ABI). ABI measurement should be important for all DM clients and all clients at risk of DM but is often ignored, causing PAD. The purpose of this study was to determine the Ankle Brachial Index (ABI) as a predictor of Peripheral Artery Disease (PAD) in patients with diabetes mellitus. The design of this study was descriptive with an observational study approach. The population in this study were all 113 diabetes mellitus clients in July 2024. The sampling
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Labrada Gónzalez, Elsy, Olga Cristina Solis Solís, and María del Carmen Yabor Labrada. "Malnutrition in children from 3 to 5 years of patate city, ecuador 2022." Interamerican Journal of Health Sciences 4 (July 21, 2024): 74. http://dx.doi.org/10.59471/ijhsc202474.

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Currently, it is responsible for almost a third of deaths in children &lt;5 years of age and a cause of intellectual and cognitive disability in the surviving population. 23.1% of children under five years of age in Ecuador have chronic child malnutrition or delayed growth, the figure increases by 28.7%. in rural communities. The main objective was to determine the incidence of child malnutrition in a CDI in Patate, Ecuador during 2022. The majority age group was from 0 to 2 years, with a predominance of males with 53.85%. Low stature predominated in the male sex with 13.33%, as well as low we
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Kakihana, Masato, Minoru Akiyama, Tadashi Nagumo та Makoto Okamoto. "An Empirical Potential Function of α-Glycine Derived from Infrared Spectroscopic Data of D-, 13C-, 15N-, and 18O-Labeled Species". Zeitschrift für Naturforschung A 43, № 8-9 (1988): 774–92. http://dx.doi.org/10.1515/zna-1988-8-911.

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AbstractThe infrared spectra (4000-100 cm-1) of the α-form crystal ofglycine (NH3+ - CH2 - COO-) and of thirteen isotopic modifications comprising D, 13C, 15N, and 18O were measured at 80 and 290 K. Excellent resolution was reached at the low temperature. In the low temperature spectra the fine structure of the nearly degenerate NH3 and ND3 antisymmetric deformational modes and the CO2-torsional bands in the vicinity of 200 cm-1 for each of the isotopic molecules, which in the low-frequency region are strongly overlapped by a number of lattice modes, clearly showed up. Based upon the frequency
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Jin, Jianqiao, Kunyang Wang, Lei Ren, et al. "Optimization Design of the Inner Structure for a Bioinspired Heel Pad with Distinct Cushioning Property." Bioengineering 10, no. 1 (2022): 49. http://dx.doi.org/10.3390/bioengineering10010049.

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In the existing research on prosthetic footplates, rehabilitation insoles, and robot feet, the cushioning parts are basically based on simple mechanisms and elastic pads. Most of them are unable to provide adequate impact resistance especially during contact with the ground. This paper developed a bioinspired heel pad by optimizing the inner structures inspired from human heel pad which has great cushioning performance. The distinct structures of the human heel pad were determined through magnetic resonance imaging (MRI) technology and related literatures. Five-layer pads with and without inne
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Edmonds, C. J., and C. L. Willis. "Aldosterone and thyroid hormone interaction on the sodium and potassium transport pathways of rat colonic epithelium." Journal of Endocrinology 124, no. 1 (1990): 47–52. http://dx.doi.org/10.1677/joe.0.1240047.

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ABSTRACT The effect of hypothyroidism on potassium adaptation (shown by increased potassium secretion in response to potassium loading) and on the action of aldosterone on potassium secretion and sodium fluxes was examined in the rat distal colon. Potassium adaptation, particularly the response to an acute potassium load, was impaired by hypothyroidism which also considerably reduced the rise of transepithelial electrical potential difference (p.d.) of total and transcellular (active) lumen-to-plasma sodium fluxes and of potassium secretion normally produced by aldosterone. These changes were,
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Haddad, P. A. "Activity of bortezomib (B) in plasma cell dyscrasia (PCD) with POEMS-like syndrome." Journal of Clinical Oncology 27, no. 15_suppl (2009): e19564-e19564. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e19564.

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e19564 Background: POEMS (polyneuropathy, organomegaly, endocrinopathy, m-protein, and skin changes) syndrome is a rare multi-system disorder associated with PCD. Although several reports revealed significant clinical benefit of IMIDs in POEMS syndrome cases that are not transplant candidates, no such published reports of B in this disease were found. Methods: We report the first case of PCD with POEMS like syndrome in addition to pulmonary hypertension, secondary right heart failure, and membranoproliferative glomerulonephritis that was successfully treated with single agent B. After presenti
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Shpitzer, Dor, Yael C. Cohen, Chava Perry, Anat Reiner-Benaim, and Irit Avivi Mazza. "Clinical Significance of a Slightly Abnormal FLC Levels/Ratio." Blood 142, Supplement 1 (2023): 4777. http://dx.doi.org/10.1182/blood-2023-188508.

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The employment of Free Light Chain (FLC) test in the community is continuously expanding and incorporated into the assessments of unexplained tiredness or nonspecific complaints, even in the absence of clear suspicion of plasma cell dyscrasia (PCD). Consequently, there has been a growing occurrence of “incidental detection” of slightly abnormal FLC tests, in the absence of additional laboratory abnormalities, and data regarding the significance of this finding are limited. The current study aims to explore the clinical significance of an “incidental” finding of slightly increased FLC test in a
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Nadeem, Beenish, Naushaba Malik, Manal Niazi, Saira Ahmad, Mariam Hassan Bukhari, and Arsalan Khalid. "Establishing Normal Range of Fetal Pulmonary Artery and Fetal Aortic Diameter in 18-26 Weeks of Gestation in Pakistani Population." Pakistan Journal of Medical & Health Sciences 16, no. 10 (2022): 482–84. http://dx.doi.org/10.53350/pjmhs221610482.

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Congenital heart diseases constitute almost 0.8 to 1.2% of newborn illnesses globally however unfortunately 64% of them remained undiagnosed on conventional anamoly scan which uses four chamber view for cardiac evaluation. In developed countries, other than routine anomaly scan, the three vessel view(3VV) has been added to look for any potential outflow tract anomalies which increased the sensitivity of screening CHD however this view is not routinely used in our clinical practice due to lack of expertise and less awareness regarding the importance of this view . We aimed to establish normal r
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Reed, John C. "Dysregulation of Apoptosis in Cancer." Journal of Clinical Oncology 17, no. 9 (1999): 2941. http://dx.doi.org/10.1200/jco.1999.17.9.2941.

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ABSTRACT: Each day, approximately 50 to 70 billion cells perish in the average adult because of programmed cell death (PCD). Cell death in self-renewing tissues, such as the skin, gut, and bone marrow, is necessary to make room for the billions of new cells produced daily. So massive is the flux of cells through our bodies that, in a typical year, each of us will produce and, in parallel, eradicate a mass of cells equal to almost our entire body weight. The morphologic ritual cells go through when experiencing PCD has been termed apoptosis and is executed by a family of intracellular proteases
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Mezzano, Diego, Teresa Quiroga, Manuela Goycoolea, et al. "Diagnostic Assessment of Patients with Inherited Mucocutaneous Hemorrhages (IMCH): Opening a Pandora Box?." Blood 104, no. 11 (2004): 4009. http://dx.doi.org/10.1182/blood.v104.11.4009.4009.

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Abstract Diagnosis of patients with IMCH is plagued with difficulties: 1. Type 1 VWD (VWD-1) and platelet function disorders (PFD), the best characterized disorders of primary hemostasis, present inherent diagnostic difficulties. 2. Bleeding may be present in healthy individuals and may be absent in patients with diagnosed diseases. 3. An unknown proportion of bleeders do not have an identifiable haemostatic disorder. We studied prospectively 280 consecutive patients (age = 14.5±9.5, range 4–48 years) with family bleeding history who had a high probability of being pathological bleeders, based
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Lu, Shan, Tianquan Zhu, Lilin Luo, Nana Ouyang, Jian Hua, and Baohong Zou. "Divergent Roles of CNGC2 and CNGC4 in the Regulation of Disease Resistance, Plant Growth and Heat Tolerance in Arabidopsis." Agronomy 12, no. 9 (2022): 2176. http://dx.doi.org/10.3390/agronomy12092176.

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Arabidopsis cyclic nucleotide-gated channels (CNGC) 2 and 4 are shown to negatively regulate disease resistance and heat tolerance and to positively regulate plant growth. Whether or not their functions in these processes are interdependent is largely unknown. Here, using the mutation of phytoalexin deficient 4 (PAD4) to inhibit the enhanced defense response and programmed cell death (PCD), we assessed the contribution of the altered defense response to the heat tolerance and plant growth in the cngc2 and cngc4 single and double mutants. The pad4 mutation reverted the enhanced disease resistan
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Zakariah, Yusof, Abdul Wahab Norhaliza, Ibrahim Syahira, Sahlan Shafishuhaza, and Che Razali Mashitah. "Modeling of submerged membrane filtration processes using recurrent artificial neural networks." International Journal of Artificial Intelligence (IJ-AI) 9, no. 1 (2020): 155–63. https://doi.org/10.11591/ijai.v9.i1.pp155-163.

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The modeling of membrane filtration processes is a challenging task because it involves many interactions from both biological and physical operational behavior. Membrane fouling behaviour in filtration processes is complex and hard to understand, and to derive a robust model is almost not possible. Therefore, it is the aim of this paper to study the potential of time series neural network based dynamic model for a submerged membrane filtration process. The developed model that represent the dynamic behavior of filtration process is later used in control design of the membrane filtration proce
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17

Jacobsson, H. "Disc brake judder considering instantaneous disc thickness and spatial friction variation." Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering 217, no. 5 (2003): 325–42. http://dx.doi.org/10.1243/095440703321645043.

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Brake judder is a braking-induced vibration. The character of judder is typical of forced vibrations passing through a critical speed. No specific friction characteristic is needed for judder to occur. In two previous models, i.e. a rotor-stator model and a whole vehicle model, the vibration during a brake application was simulated. The vibrations were assumed to be driven by a brake torque variation (BTV) during a wheel revolution. The BTV was assumed to be proportional to the brake pressure variation (BPV) which was measured. Moreover, the proportionality constant was assumed to be independe
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18

Kovacs, B., and G. C. Tsokos. "Cross-linking of the Fas/APO-1 antigen suppresses the CD3-mediated signal transduction events in human T lymphocytes." Journal of Immunology 155, no. 12 (1995): 5543–49. http://dx.doi.org/10.4049/jimmunol.155.12.5543.

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Abstract The Fas/APO-1 Ag, a member of the TNF-R family, mediates apoptosis (programmed cell death, PCD). PCD has been recognized to be important in the regulation of normal and autoimmune responses. However, the underlying molecular mechanisms are not fully known. To elucidate the role of the Fas Ag in lymphocyte activation, we investigated the influence of Fas Ag cross-linking on CD3/TCR-mediated signal transduction in IL-2-dependent human T cell lines. Early signal transduction events were evaluated in 10-day-old T cell lines using anti-Fas and anti-CD3 mAbs. Incubation of Indo-1-loaded cel
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19

Smith, Jodi L., Jon Hobbs, Aonan Tang, et al. "Network Comparison of Epileptogenic Human Cortex and Excited Rat Cortex." Journal of Neurosurgery: Pediatrics 1, no. 4 (2008): A351—A352. http://dx.doi.org/10.3171/ped/2008/1/4/paper4.

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Introduction Epileptogenicity of neuronal tissues requires both altered excitability and altered synchronization of neurons. However, the network-level mechanisms responsible for neuronal hyperexcitability and synchronization remain unknown, and there is much to learn regarding how even small networks of neurons interact. The present study examines local and network properties of cortical neurons from epileptogenic human and excited (“epileptic”) rat cortex. Methods Epileptogenic cortex was harvested from pediatric patients with medically refractory seizures undergoing resective surgery. Local
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Azari, Omid, Reza Nikzad, Alireza Farsinezhad, and Shahrzad Azizi. "Comparative Regenerative Effects of Allogeneic Bone Marrow and Patellar Ligament Fat Pad Mesenchymal Stem Cells on Experimental Superficial Digital Flexor Tendonitis in New Zealand Rabbits." Iranian Journal of Veterinary Medicine 17, no. 4 (2023): 353–62. http://dx.doi.org/10.32598/ijvm.17.4.1005314.

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Background: Cell therapy is applied in tendonitis to speed the healing process of tendon tissue and restore its functional properties. Almost all types of stem cells can differentiate from the recipient cells after transplantation. Objectives: The main goal of this study is to compare the effects of two sources of mesenchymal stem cells on tendon regeneration. Methods: This study randomly divided 32 New Zealand rabbits into 4 groups. The bacterial collagenase was induced at the superficial digital flexor tendon (SDFT) of all rabbits, and the treatment was performed 48 hours after collagenase i
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Pore, Nabendu, Kevin P. Schifferli, Noel R. Monks, et al. "Discovery and Development of MEDI7247, a Novel Pyrrolobenzodiazepine (PBD)-Based Antibody Drug Conjugate Targeting ASCT2, for Treating Hematological Cancers." Blood 132, Supplement 1 (2018): 4071. http://dx.doi.org/10.1182/blood-2018-99-119836.

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Abstract The neutral amino acid transporter, ASCT2, is frequently overexpressed in several cancers to sustain "glutamine addiction" of cancer cells. High expression of ASCT2 is often associated with poor disease prognosis. Immuno-histochemistry (IHC) on formalin-fixed paraffin embedded (FFPE) tissue samples revealed high prevalence of membranous ASCT2 expression in several hematological cancers, including MM, AML, and DLBCL summarized in Table1. ASCT2 expression was predominantly on the plasma membrane of the carcinoma cells. ASCT2 staining was observed in almost all the samples with high posi
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Boezaart, André P., Alberto Prats-Galino, Olga C. Nin, et al. "The Posterior Lumbar Epidural Space: Three-Dimensional Reconstruction of High-Resolution MRI: Real and Potential Epidural Spaces and Their Content In Vivo." Pain Medicine 20, no. 9 (2019): 1687–96. http://dx.doi.org/10.1093/pm/pnz016.

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Abstract Objective Our aim was to study the posterior lumbar epidural space with 3D reconstructions of magnetic resonance images (MRIs) and to compare and validate the findings with targeted anatomic microdissections. Design We performed 3D reconstructions of high-resolution MRIs from seven patients and normal-resolution MRIs commonly used in clinical practice from 196 other random patients. We then dissected and photographed the lumbar spine areas of four fresh cadavers. Results From the 3D reconstructions of the MRIs, we verified that the distribution of the posterior fat pad had an irregula
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Alaterre, Elina, Sara Ovejero, Marion Espéli, et al. "Integrative Single-Cell RNA-Seq and Single-Cell ATAC-Seq Analysis of Human Plasma Cell Differentiation." Blood 142, Supplement 1 (2023): 86. http://dx.doi.org/10.1182/blood-2023-181507.

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Plasma cells (PC) are highly specialized cells representing the end stage of B cell differentiation. They play an important role in humoral immunity by synthesizing and secreting antibodies protecting the host against infections. We have shown that PC differentiation (PCD) can be reproduced in vitrofrom memory B cells (MBC). MBC differentiate into CD20 low/-CD38 - pre-plasmablasts (prePB), CD20 -CD38 +CD138 - plasmablasts (PB) and CD20 -CD38 +CD138 + PC. The molecular changes occurring during PCD are recapitulated in this in vitrodifferentiation model. However, a major challenge exists to deci
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Beaulieu, M. C., I. Gaboury, N. Carrier, et al. "PARE0016 MINDFULNESS-BASED STRESS REDUCTION TO IMPROVE DEPRESSIVE SYMPTOMS AND RHEUMATOID ARTHRITIS-RELATED CLINICAL OUTCOMES: RESULTS FROM A FEASIBILITY AND ACCEPTABILITY TRIAL." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1294.2–1294. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6339.

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Background:Despite available highly effective pharmacological treatments, up to 30% of current rheumatoid arthritis (RA) patients remain in quasi-remission, where inflammation is controlled but patients still report unacceptable levels of negative impact of RA (high Patient Global Assessment (PGA) on a 0-10 visual analog scale). PGA levels correlated with depressive symptoms assessed by Center for Epidemiologic Studies- Depression (CES-D) scores. Mindfulness-Based Stress Reduction (MBSR) is relatively inexpensive and reduces both anxiety and depression in several conditions.Objectives:To compl
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Parajuli, Surya B., Heera KC, A. Mishra, P. Bhattarai, M. Shrestha, and Kundan Srivastav. "Chaupadi during menstruation still a major community health challenge: perspective from Mid-Western Nepal." BIBECHANA 16 (November 22, 2018): 228–35. http://dx.doi.org/10.3126/bibechana.v16i0.21645.

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Introduction: Menstruation, a normal physiological process in reproductive life of female still has many misconceptions. Knowledge of menstrual hygiene and menstrual sanitation practices affects the health of female. Lack of awareness on menstrual care practice is a challenge for community health. Objective: The objective of this study was to find knowledge and practice on menstrual hygiene; and perspective of Chaupadi (menstrual shed) among the reproductive age group female. Methodology: A community based mixed method study having cross sectional study as quantitative domain and phenomenologi
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Baurier-Aymat, Sandra, Abigail Jiménez-Franco, Josep Roqué-Rosell, et al. "Nanoscale Structure of Zoned Laurites from the Ojén Ultramafic Massif, Southern Spain." Minerals 9, no. 5 (2019): 288. http://dx.doi.org/10.3390/min9050288.

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We report the first results of a combined focused ion beam and high-resolution transmission electron microscopy (FIB/HRTEM) investigation of zoned laurite (RuS2)-erlichmanite (OS2) in mantle-hosted chromitites. These platinum-group minerals form isolated inclusions (&lt;50 µm across) within larger crystals of unaltered chromite form the Ojén ultramafic massif (southern Spain). High-magnification electron microscopy (HMEM), high angle-annular dark field (HAADF) and precession electron diffraction (PED) data revealed that microscale normal zoning in laurite consisting of Os-poor core and Os-rich
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Ananth, P. Vijai, and Surendra Kumar Bouddh. "Intensive care unit prophylaxis and its outcome in a rural tertiary care hospital: an observational study." International Journal of Basic & Clinical Pharmacology 7, no. 9 (2018): 1742. http://dx.doi.org/10.18203/2319-2003.ijbcp20183482.

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Background: Intensive Care Unit is used to treat patients closer to their beds, in order to observe them more as distinct people to almost all the critically-ill patients.Methods: One hundred admitted patients in the ICU, 25 each sets of the patients observed their prophylactic management to prevent stress ulcer, pressure ulcer, UTI and chest infection, observations noted for the 7 days, directly by seeing and by cross-checked patient’s case-sheets.Results: There were 2 (8%) patients developed stress ulcer, 1 (4%) Catheter associated bacteriuria, 2 (8%) patients grade II pressure ulcer, and 5
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Clemente-Chavez, A., A. Figueroa-Soto, F. R. Zúñiga, M. Arroyo, M. Montiel, and O. Chavez. "Seismicity in northeast edge of the Mexican Volcanic Belt (MVB), activation of an undocumented fault: the Peñamiller earthquake sequence of 2011, Queretaro, Mexico." Natural Hazards and Earth System Sciences Discussions 1, no. 1 (2013): 323–52. http://dx.doi.org/10.5194/nhessd-1-323-2013.

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Abstract. The Peñamiller town, in the Queretaro state, Mexico is located at the northeast border of the seismogenic zone known as the Mexican Volcanic Belt (MVB), which covers a central fringe of Mexico with east-west orientation. In this town, a sequence of small earthquakes occurred during the end of 2010 and beginning of 2011. Seismicity frequent in of the continental regimen of central Mexico are not common, however, it is known that there are precedents of large earthquakes (Mw magnitude greater than 6.0) occurring in this zone. In order to enrich seismic information, which has not been a
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Khan, Muhammad Adnan, Khalid Khan, Adnan Daud Khan, Zubair Ahmad Khan, Shahbaz Khan, and Abdullah Mohammed. "A model-based approach for detecting and identifying faults on the D.C. side of a P.V. system using electrical signatures from I-V characteristics." PLOS ONE 17, no. 3 (2022): e0260771. http://dx.doi.org/10.1371/journal.pone.0260771.

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With the development of distributed generation and the corresponding importance of the P.V. (photovoltaic) system, it is desired to operate a P.V. system efficiently and reliably. To ensure such an operation, a monitoring system is required to diagnose the health of the system. This paper aims to analyze a P.V. system under various operating conditions to identify parameters–derived from the I-V (current-voltage) characteristics of the P.V. system–that could serve as electrical signatures to various faulty operations and facilitate in devising a monitoring algorithm for the system. A model-bas
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Mokaya, Joy N., Mary Muiruri, and Francisca Ongecha. "Management of Menstrual Hygiene among School-Going Adolescent Girls in an Informal Settlement in Nairobi, Kenya, Amidst COVID-19 Pandemic." International Journal of Health Sciences and Research 12, no. 2 (2022): 246–59. http://dx.doi.org/10.52403/ijhsr.20220235.

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Puberty is a critical stage for key social-emotional changes and intellectual developments in the transition to adulthood. The lack of knowledge about menstruation and the inefficiency of resources to properly manage body changes consequently leads to anxiety and fear during the transition for some adolescents, especially in low- and middle-income countries. Every girl needs to have access to learning, wellbeing, and future forecasts about menstruation and guidance towards effective menstrual hygiene management. Several adolescent girls and women in informal settlements have a partial understa
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Clemente-Chavez, A., A. Figueroa-Soto, F. R. Zúñiga, M. Arroyo, M. Montiel, and O. Chavez. "Seismicity at the northeast edge of the Mexican Volcanic Belt (MVB) and activation of an undocumented fault: the Peñamiller earthquake sequence of 2010–2011, Querétaro, Mexico." Natural Hazards and Earth System Sciences 13, no. 10 (2013): 2521–31. http://dx.doi.org/10.5194/nhess-13-2521-2013.

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Abstract. The town of Peñamiller in the state of Querétaro, Mexico, is located at the northeast border of the seismogenic zone known as the Mexican Volcanic Belt (MVB), which transects the central part of Mexico with an east–west orientation. In the vicinity of this town, a sequence of small earthquakes occurred during the end of 2010 and beginning of 2011. Seismicity in the continental regimen of central Mexico is not too frequent; however, it is known that there are precedents of large earthquakes (Mw magnitude greater than 6.0) occurring in this zone. Three large earthquakes have occurred i
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Topcu, Dilara Bal, Yesim Er Oztas, and Ahmet Caner Kahraman. "Critical values for carbon monoxide in cases admitted to the emergency department in a local hospital." American Journal of Clinical Pathology 162, Supplement_1 (2024): S187. http://dx.doi.org/10.1093/ajcp/aqae129.409.

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Abstract Carbon monoxide (CO) poisoning has been an important concern in winter particularly due to malfunctioning coal stoves, in many developing countries, including Turkey. Winter months, especially February, were the most dangerous periods for CO exposure. Carbon monoxide has no color or smell so has known as the silent killer. Brain, heart, and other organs are under risk in CO poisoning. Because patients usually present with non-specific symptoms, CO poisoning should be considered in the differential diagnosis of unexplained nausea and vomiting, neurological or cardiac signs and symptoms
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Shelley, Farida Easmin. "Perception and Practice about Menstrual Health/Hygiene Among Adolescent Girls in Barisal District." Ibrahim Cardiac Medical Journal 11, no. 1 (2022): 79–85. http://dx.doi.org/10.3329/icmj.v11i1.58710.

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Background &amp; Objective: Although menstruation is a natural physiological process and usually goes away without any complex problems provided proper care is taken during the period. However, menstruation is linked with religious and cultural meanings that can affect the perceptions of young girls and the ways in which the adult communities around them respond to their felt-needs. So, menstruation-associated complaints are not uncommon. The present study was, therefore, intended to determine the perception and practice of adolescent girls about menstruation in Barisal District.&#x0D; Methods
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Sonneveld, Pieter, Hans-Juergen Salwender, Bronno Van Der Holt, et al. "Bortezomib Induction and Maintenance in Patients with Newly Diagnosed Multiple Myeloma: Long-Term Follow-up of the HOVON-65/GMMG-HD4 Trial." Blood 126, no. 23 (2015): 27. http://dx.doi.org/10.1182/blood.v126.23.27.27.

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Abstract Background: We reported better PFS and OS in transplant eligible patients with newly diagnosed Multiple Myeloma (MM) who were treated with bortezomib during induction and maintenance, when compared with standard treatment in the HOVON-65/GMMG-HD4 trial. (P. Sonneveld et al., J Clin Oncol 30:2946-2955, 2012). Here the long-term follow up data are presented. Methods: 827 eligible patients were randomized to induction therapy with VAD (vincristine, doxorubicin, dexamethasone) or PAD (bortezomib, doxorubicin, dexamethasone) followed by high-dose melphalan (once or twice) and autologous st
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35

Galton, Peter M., Omar Rafael Regalado-Fernández, and James O. Farlow. "Bones of dinosaurs and other reptiles from the Triassic-Jurassic of the Connecticut Valley: Over 200 years of published history." Revue de Paléobiologie 2025, no. 2 (2025): 1–45. https://doi.org/10.5281/zenodo.14793417.

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The bones from the Connecticut Valley in eastern USA came from the Newark Supergroup with the Lower Jurassic remains coming from the uppermost red sandstone bed (Portland Formation, Middle Hettangian) in Connecticut, and the Longmeadow Formation in Massachusetts. The dinosaurs mostly represent herbivorous or omnivorous facultatively bipedal early sauropodomorph non-eusauropod (&ldquo;prosauropod&rdquo;) dinosaurs. Two fragmentary records of animals with a body length of ~1.5&nbsp;m were discovered during blasting for a water well. The first (YPM VP 2125), in 1818 from East Windsor, Conn., is t
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Schreiber, S., A. P. Bleakman, M. C. Dubinsky, et al. "A190 THE IMPACT OF BOWEL URGENCY ON THE LIVES OF PATIENTS WITH ULCERATIVE COLITIS IN THE US AND EUROPE: COMMUNICATING NEEDS AND FEATURES OF IBD EXPERIENCES (CONFIDE) SURVEY." Journal of the Canadian Association of Gastroenterology 6, Supplement_1 (2023): 35–36. http://dx.doi.org/10.1093/jcag/gwac036.190.

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Abstract Background Moderate to severe ulcerative colitis (UC) exerts a significant burden on patients’ lives. Patients with UC report that bowel urgency has a substantial negative impact on their quality of life and psychosocial functioning, however, this symptom is missing from most disease activity indices. Purpose The Communicating Needs and Features of IBD Experiences (CONFIDE) study aims to increase understanding of the impact of symptoms, including bowel urgency, on the lives of patients (pts) with moderate to severe UC and Crohn’s disease in the United States (US), Europe (EUR), and Ja
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Bayat, Reza, Shahin Koohmanaee, Nejat Mahdieh, et al. "A Case of Pyruvate Carboxylase Deficiency With Longer Survival and Normal Laboratory Findings." ACTA MEDICA IRANICA, November 16, 2021. http://dx.doi.org/10.18502/acta.v59i10.7772.

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Pyruvate carboxylase deficiency (PCD) is a rare autosomal recessive defect in a biotin-containing enzyme, Pyruvate carboxylase, which is considered as an enzyme of TCA-cycle regulation, gluconeogenesis, lipogenesis, and biosynthesis of neurotransmitters. Increased lactate to pyruvate ratio and decreased three hydroxybutyrates to acetoacetate are the main biochemical features of PCD. The elevated level of Citrulline, Proline, and Lysine with a short life span has been reported previously. Patients’ survival in almost all cases is below three months. Here, the authors aimed to report a girl with
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Urbiola-Soto, Leonardo, and Paolo Pennacchi. "Rotor Stability Effects of Tilting Pad Journal Bearings with Assembled Clearance Asymmetry." Journal of Engineering for Gas Turbines and Power, May 19, 2022. http://dx.doi.org/10.1115/1.4054606.

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Abstract This paper presents component and system-level analyses to understand the stiffness, damping and rotor stability effects of tilting pad journal bearings (TPJB) with assembled clearance variation across pads. This variation results from a normal manufacturing process of the bearing components, i.e. shaft, bearing shell, pad radius, and pad thickness, whose machining tolerances add in a close loop producing a different assembled clearance per pad. The results are compared to the standard analysis practice of uniformly setting all pads assembled clearance to its maximum and minimum stack
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Federica, Ricci, Russo Edda, Renzi Daniela, et al. "Characterization of the “gut microbiota-immunity axis” and microbial lipid metabolites in atrophic and potential celiac disease." Frontiers in Microbiology 13 (September 30, 2022). http://dx.doi.org/10.3389/fmicb.2022.886008.

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IntroductionPotential celiac disease (pCD) is characterized by genetic predisposition, positive anti-endomysial and anti-tissue transglutaminase antibodies, but a normal or almost normal jejunal mucosa (e.g., minor histological abnormalities without villous atrophy). To gain further insights into basic mechanisms involved in the development of intestinal villous atrophy, we evaluated and compared the microbial, lipid, and immunological signatures of pCD and atrophic CD (aCD).Materials and methodsThis study included 17 aCD patients, 10 pCD patients, and 12 healthy controls (HC). Serum samples f
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San Andrés, Luis, and Yujiao Tao. "The Role of Pivot Stiffness on the Dynamic Force Coefficients of Tilting Pad Journal Bearings." Journal of Engineering for Gas Turbines and Power 135, no. 11 (2013). http://dx.doi.org/10.1115/1.4025070.

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Recent comprehensive experimental data showcasing the force coefficients of commercial size tilting pad journal bearings has brought to rest the long standing issue on the adequacy of the [K,C,M] physical model to represent frequency independent bearing force coefficients, in particular viscous damping. Most experimental works test tilting pad journal bearings (TPJBs) with large preloads, operating over a large wide range of rotor speeds, and with null to beyond normal specific loads. Predictions from apparently simple fluid film bearing models stand poor against the test data which invariably
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Zungu, Thokozani, Shaffi Mdala, Halima Sumayya Twabi, Petros Kayange, and Faik Gelisken. "Evaluation of Tele-Education in Malawi for Detection of Macular Features Using Optical Coherence Tomography." Klinische Monatsblätter für Augenheilkunde, January 23, 2025. https://doi.org/10.1055/a-2441-7861.

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Abstract Purpose The study aimed to assess the reliability of tele-education in training a Malawian ophthalmology resident to interpret optical coherence tomography (OCT) images of patients with macular conditions. Methods This was a retrospective analysis of 1000 macula-centered OCT image series from 1000 eyes of 1000 consecutive patients from Malawi, which involved initial interpretation by a German retina specialist (observer 1) (T0). Observer 1 then trained a Malawian resident (observer 2) via email, and observer 2 independently interpreted images at T1, followed by face-to-face training i
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Regi, Soumya Susan, Aparna Irodi, Shyamkumar N. Keshava, and Sunil Agarwal. "Balanced Steady-State Free Precision and Time of Flight Noncontrast Magnetic Resonance Angiography in Peripheral Arterial Disease." Journal of Clinical Interventional Radiology ISVIR, July 6, 2021. http://dx.doi.org/10.1055/s-0041-1730845.

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Abstract Purpose To determine the diagnostic efficacy of balanced steady-state free precession (bSSFP) and time-of-flight (TOF)-based noncontrast magnetic resonance angiography (NC-MRA) in lower limb peripheral arterial disease (PAD). Material and Methods 10 patients with suspected PAD underwent both NC-MRA (bSSFP and 2D TOF) and contrast-enhanced MR angiography (CE-MRA)/CT angiography (CTA). A total of 170 arterial segments (17 segments in each patient) were analyzed on NC-MRA and compared with CE-MRA/CTA for quality of images and for estimating the degree of stenoses. Image quality was grade
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Hata, Junya, Kanako Matsuoka, Hidenori Akaihata, et al. "Prognosis of lower urinary tract symptoms and function after robot‐assisted radical prostatectomy in patients with preoperative low bladder contractility: A prospective, observational study." Neurourology and Urodynamics, August 21, 2024. http://dx.doi.org/10.1002/nau.25577.

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AbstractObjectivesTo examine the prognosis of lower urinary tract symptoms and function after robot‐assisted radical prostatectomy (RARP) in patients with low preoperative bladder contractility.MethodsA total of 115 patients who underwent RARP were enrolled and divided into two groups by preoperative urodynamic findings: normal (patients with bladder contractility index [BCI] ≥ 100; n = 70) and low contractility (patients with BCI &lt; 100; n = 45) groups. Lower urinary tract symptoms and function parameters were prospectively evaluated at 1, 3, 6, 9, and 12 months after RARP in both groups.Re
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Fendrik, K., D. Endrei, K. Biro, K. Koltai, K. Toth, and G. Kesmarky. "Can we boost screening for peripheral arterial disease?" European Heart Journal 43, Supplement_2 (2022). http://dx.doi.org/10.1093/eurheartj/ehac544.1965.

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Abstract Despite the high prevalence of peripheral artery disease (PAD), the diagnosis is often delayed. The delayed diagnosis is due in part to comorbidities which can mask PAD symptoms, and in large part to the low use of conventional diagnostic tools. For PAD diagnostics, the guidelines recommend Doppler-based ankle-brachial index (ABI). The method is time consuming and requires skills. The toe pressure measurement which helps to eliminate the falsely elevated ankle pressures due to mediasclerosis is an almost neglected method for screening. In recent years, automatic, oscillometric four-li
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Nishimura, Takahiro, Hideaki Watanabe, Naoya Taki, Ichiro Kikkawa, and Katsushi Takeshita. "Standard radiographic values for the acetabulum in Japanese adolescents: a cross-sectional study." BMC Musculoskeletal Disorders 24, no. 1 (2023). http://dx.doi.org/10.1186/s12891-023-06368-z.

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Abstract Background Most previous reports of normal acetabular radiographic values focused on adults or elderly people. Recent reports have described premature hip osteoarthritis in adolescents not caused by acetabular dysplasia. In addition, there is a certain failure rate of surgical treatment for young patients with borderline acetabular dysplasia. Accurate indices for treatment of adolescent hips are unclear because standard measurement values of the adolescent acetabulum have not been reported. Methods This cross-sectional study involved 552 Japanese adolescents aged 12–18 years who had s
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Patel, Erica, and Marc Weigensberg. "MON-055 A Rare Case of a Macroadenoma Causing Cushing Syndrome in a Pediatric Patient." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.1554.

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Abstract Background: Pediatric Cushing Syndrome, a rare diagnosis, is almost always caused by pituitary microadenomas less than 5 mm in children older than 6 years old. We report on a 9-year-old girl with a 2.3 cm pituitary macroadenoma, whose ACTH and urinary 24-hour free cortisol were the highest recorded at our institution. Clinical Case: A 9-year-old pre-pubertal female presented with six months of frontal headaches, rapid weight gain, and hirsutism. Two months prior she developed fatigue and proximal muscle weakness and pain. On physical exam, she had plethoric round facies with acne and
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Jadhav, Pranavi, Sanjeev Naik, Ramen Sinha, Prabhat Tiwari, and Revanth Kumar Salavadi. "POSTOPERATIVE OUTCOMES OF COLLAGEN SHEET VERSUS BUCCAL FAT PAD IN THE RESURFACE OF THE RAW AREA FOLLOWING THE EXCISION OF FIBROUS BANDS IN OSMF- PROSPECTIVE CLINICAL STUDY." INDIAN JOURNAL OF APPLIED RESEARCH, January 1, 2025, 65–67. https://doi.org/10.36106/ijar/4002196.

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This study was designed to compare the use of collagen sheet, on one side and BFP on the contra lateral side to resurface the raw area following the excision of fibrous bands. This prospective study comprised 46 patients reporting to the department of Oral and Maxillofacial Surgery, SSCDS, Hyderabad with a chief complaint of reduced mouth opening. Patients were examined postoperatively on the first day, first week, second week, third week, fourth week, eighth week, three months, and six months. Pain, interincisal opening, edema, and graft epithelialization were examined postoperatively. The fi
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Asai, Kunio, Takeshi Kudo, and Hideo Yoda. "Experimental Validation of Fretting Fatigue Strength and Fretting Wear Rate at Contact Surface of Turbine-Blade-Shroud Cover." Journal of Engineering for Gas Turbines and Power 136, no. 4 (2013). http://dx.doi.org/10.1115/1.4025833.

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In continuously coupled blade structures, fretting fatigue and wear have to be considered as supposed failure modes at the contact surface of the shroud cover, which is subject to steady contact pressure from centrifugal force and the vibratory load of the blade. We did unique fretting tests that modeled the structure of the shroud cover, where the vibratory load is only carried by the contact friction force, i.e., a type of friction. What was investigated in this study are fretting fatigue strength, wear rate, and friction characteristics, such as friction coefficient and slip-range of 12%-Cr
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Borreguero, Cédric Francis, Stephan Wueest, Constanze Hantel, et al. "Deoxyguanosine kinase mutation F180S is associated with a lean phenotype in mice." International Journal of Obesity, January 28, 2023. http://dx.doi.org/10.1038/s41366-023-01262-z.

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Abstract Background Deoxyguanosine kinase (DGUOK) deficiency is one of the genetic causes of mitochondrial DNA depletion syndrome (MDDS) in humans, leading to the hepatocerebral or the isolated hepatic form of MDDS. Mouse models are helpful tools for the improvement of understanding of the pathophysiology of diseases and offer the opportunity to examine new therapeutic options. Methods Herein, we describe the generation and metabolic characterization of a mouse line carrying a homozygous DguokF180S/F180S mutation derived from an N-ethyl-N-nitrosourea-mutagenesis screen. Energy expenditure (EE)
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Bacci, Christian, Cerrato Alessia, Christian Bacci, Mariagrazia Boccuto, Rosario Marchese Ragona, and Zanette Gastone. "Maxillary Sinusitis of Odontogenic Origin in Relation to Ectopic 2.8 Associated with Follicular Dentigerous Cyst – Combined Transnasal and Oral Endoscopic Approach: A Case Report." Dental Oral Biology and Craniofacial Research, April 22, 2020, 1–3. http://dx.doi.org/10.31487/j.dobcr.2020.02.01.

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Purpose: To describe the management of orosinusal pathology by combined transnasal and oral endoscopy. Methods: The 54-year-old patient underwent a dental and otolaryngological evaluation for left odontogenic maxillary sinusitis in relation to plausible dental follicular cyst of ectopic element 2.8. The symptoms reported at the time of access to the hospital were nasal obstruction and nocturnal rhonchopathy. In the ENT evaluation by videorhinoscopy with rigid optics, complex deviation of the nasal septum was revealed, without any evident formation or pathological secretion. On inspection of th
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