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Articles de revues sur le sujet « Alternative therapeutics »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

Rodrigues, Célia F., Maria E. Rodrigues, and Mariana C. R. Henriques. "Promising Alternative Therapeutics for Oral Candidiasis." Current Medicinal Chemistry 26, no. 14 (2019): 2515–28. http://dx.doi.org/10.2174/0929867325666180601102333.

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:Candida is the main human fungal pathogen causing infections (candidiasis), mostly in the elderly and immunocompromised hosts. Even though Candida spp. is a member of the oral microbiota in symbiosis, in some circumstances, it can cause microbial imbalance leading to dysbiosis, resulting in oral diseases. Alternative therapies are urgently needed to treat oral candidiasis (usually associated to biofilms), as several antifungal drugs’ activity has been compromised. This has occurred especially due to an increasing occurrence of drugresistant in Candida spp. strains. The overuse of antifungal m

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Ortiz, Mariola Vazquez. "Alternative Medicine: Incorporation into Therapeutics Topics." American Journal of Pharmaceutical Education 62, no. 2 (1998): 208–12. http://dx.doi.org/10.1016/s0002-9459(24)01980-6.

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Kole, Ryszard, Marla Vacek, and Tiffany Williams. "Modification of Alternative Splicing by Antisense Therapeutics." Oligonucleotides 14, no. 1 (2004): 65–74. http://dx.doi.org/10.1089/154545704322988067.

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Ovcharenko, Dmitriy, Dmitry Mukhin, and Galina Ovcharenko. "Alternative Cancer Therapeutics: Unpatentable Compounds and Their Potential in Oncology." Pharmaceutics 16, no. 9 (2024): 1237. http://dx.doi.org/10.3390/pharmaceutics16091237.

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Cancer remains a leading cause of death globally. Cancer patients often seek alternative therapies in addition to, or instead of, conventional treatments like chemotherapy, radiation, and surgery. The progress in medical advancements and early detection provides more treatment options; however, the development of cancer drugs requires a significant amount of time, demands substantial investments, and results in an overall low percent of regulatory approval. The complex relationship between patent protection and pharmaceutical innovation complicates cancer drug development and contributes to hi

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Kroll, D. "Cannabinoids as Therapeutics." Focus on Alternative and Complementary Therapies 11, no. 3 (2010): 257. http://dx.doi.org/10.1111/j.2042-7166.2006.tb04701.x.

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Sá, Sara, Ruben Fernandes, Álvaro Gestoso, et al. "Cutibacterium acnes Dysbiosis: Alternative Therapeutics for Clinical Application." Applied Sciences 13, no. 21 (2023): 12086. http://dx.doi.org/10.3390/app132112086.

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Cutibacterium acnes (C. acnes) is a Gram-positive anaerobic facultative bacterium that is part of the human skin commensal microbiome. It colonizes various regions of the body, including the face, back, and chest. While typically a harmless commensal, under certain conditions, C. acnes can become pathogenic, leading to or promoting conditions such as acne vulgaris (AV), post-surgical infections, prostate cancer, and sarcoidosis. Current treatments for C. acnes infections often involve antibiotics, but the rise of antibiotic resistance has raised concerns. This review presents the virulence fac

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Collier, Joe. "Zanamivir: an alternative translation." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 356, no. 1416 (2001): 1945–46. http://dx.doi.org/10.1098/rstb.2001.1039.

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This paper offers an alternative view to that given elsewhere regarding the value of zanamivir as an agent for treating patients who develop influenza symptoms. The position taken here has developed as a result of an analysis of the data that was undertaken by the journal Drug and Therapeutics Bulletin .

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Rajashekaraiah, Vani, and Anusha Berikai Ananthakrishna. "Drug-induced thrombocytopenia – etiology and alternative therapeutic approaches." European Journal of Clinical and Experimental Medicine 21, no. 3 (2023): 617–26. http://dx.doi.org/10.15584/ejcem.2023.3.15.

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Introduction and aim. The cumulative incidence of drug-induced thrombocytopenia (DIT) is 10 cases per one million people per year with a prevalence of approximately 25% in critically ill patients. This review provides a comprehensive view of drug-induced thrombocytopenia, diagnosis, underlying mechanisms, common strategies in therapeutics, and potential alternatives. Material and methods. Databases such as “Google Scholar”, “PubMed”, “Medline” and “MDPI” was used for literature review with the keywords, “platelets”, “platelet disorders”, “thrombocytopenia”, “drug-induced”, “oxidative stress” “

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Wuellner, Ulrich, and Dragan Grabulovski. "Alternative Scaffolds as Therapeutics in Cancer and Other Diseases." Forum on Immunopathological Diseases and Therapeutics 5, no. 1-2 (2014): 101–14. http://dx.doi.org/10.1615/forumimmundisther.2015014027.

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Oltean, Sebastian. "Modulators of alternative splicing as novel therapeutics in cancer." World Journal of Clinical Oncology 6, no. 5 (2015): 92. http://dx.doi.org/10.5306/wjco.v6.i5.92.

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Engel, Linda W., and Stephen E. Straus. "Development of therapeutics: opportunities within complementary and alternative medicine." Nature Reviews Drug Discovery 1, no. 3 (2002): 229–37. http://dx.doi.org/10.1038/nrd750.

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Imaga, Ngozi Awa. "Phytomedicines and Nutraceuticals: Alternative Therapeutics for Sickle Cell Anemia." Scientific World Journal 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/269659.

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Sickle cell anemia is a genetically inherited disease in which the “SS” individual possesses an abnormal beta globin gene. A single base substitution in the gene encoding the humanβ-globin subunit results in replacement ofβ6 glutamic acid by valine, leading to the devastating clinical manifestations of sickle cell disease. This substitution causes drastic reduction in the solubility of sickle cell hemoglobin (HbS) when deoxygenated. Under these conditions, the HbS molecules polymerize to form long crystalline intracellular mass of fibers which are responsible for the deformation of the biconca

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Yang, Quan, Jinyao Zhao, Wenjing Zhang, Dan Chen, and Yang Wang. "Aberrant alternative splicing in breast cancer." Journal of Molecular Cell Biology 11, no. 10 (2019): 920–29. http://dx.doi.org/10.1093/jmcb/mjz033.

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Abstract Alternative splicing is critical for human gene expression regulation, which plays a determined role in expanding the diversity of functional proteins. Importantly, alternative splicing is a hallmark of cancer and a potential target for cancer therapeutics. Based on the statistical data, breast cancer is one of the top leading causes of cancer-related deaths in women worldwide. Strikingly, alternative splicing is closely associated with breast cancer development. Here, we seek to provide a general review of the relationship between alternative splicing and breast cancer. We introduce

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Luo, Jiaoyang, Dan Yan, Meihua Yang, Xiaoping Dong, and Xiaohe Xiao. "Multicomponent Therapeutics of Berberine Alkaloids." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/545898.

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Although berberine alkaloids (BAs) are reported to be with broad-spectrum antibacterial and antiviral activities, the interactions among BAs have not been elucidated. In the present study, methicillin-resistantStaphylococcus aureus(MRSA) was chosen as a model organism, and modified broth microdilution was applied for the determination of the fluorescence absorption values to calculate the anti-MRSA activity of BAs. We have initiated four steps to seek the optimal combination of BAs that are (1) determining the anti-MRSA activity of single BA, (2) investigating the two-component combination to

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McKay, Tina B., Rachael N. Parker, Morgan J. Hawker, Meghan McGill, and David L. Kaplan. "Silk-Based Therapeutics Targeting Pseudomonas aeruginosa." Journal of Functional Biomaterials 10, no. 3 (2019): 41. http://dx.doi.org/10.3390/jfb10030041.

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Pseudomonas aeruginosa (P. aeruginosa) infections may lead to severe damage of the cornea, mucosa, and skin. The highly aggressive nature of P. aeruginosa and the rise in multi-drug resistance, particularly in nosocomial settings, lead to an increased risk for permanent tissue damage and potentially death. Thus, a growing need exists to develop alternative treatments to reduce both the occurrence of bacterial infection and biofilm development, as well as pathological progression post-infection. Silk derived from Bombyx mori silkworms serves as a unique biomaterial that is biocompatible with lo

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Kemper, Kathi J. "Separation or Synthesis: A Holistic Approach to Therapeutics." Pediatrics In Review 17, no. 8 (1996): 279–83. http://dx.doi.org/10.1542/pir.17.8.279.

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Over the past 50 years, health care has grown more complex and specialized. Health-care institutions now are staffed with an array of specialist physicians, social workers, psychologists, therapists, and nutritionists as well as general practitioners and nurses. The types of providers outside of the hospital are even more numerous and diverse: physicians; nurses; nurse practitioners; chiropractors; counselors; acupuncturists; herbalists; spiritual healers; and purveyors of nutritional supplements, aromatherapy, crystals, and more. Intent on distinguishing their "products," providers focus on d

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Rivera-Espinosa, Liliana, Esaú Floriano-Sánchez, José Pedraza-Chaverrí, et al. "Contributions of Microdialysis to New Alternative Therapeutics for Hepatic Encephalopathy." International Journal of Molecular Sciences 14, no. 8 (2013): 16184–206. http://dx.doi.org/10.3390/ijms140816184.

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Logan, Michael H., and Kaja Finkler. "Spiritualist Healers in Mexico: Successes and Failures of Alternative Therapeutics." Anthropologica 30, no. 1 (1988): 102. http://dx.doi.org/10.2307/25605253.

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Behar, Ruth, and Kaja Finkler. "Spiritualist Healers in Mexico: Successes and Failures of Alternative Therapeutics." Contemporary Sociology 16, no. 3 (1987): 404. http://dx.doi.org/10.2307/2070346.

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Bessa, Cláudia, Paulo Matos, Peter Jordan, and Vânia Gonçalves. "Alternative Splicing: Expanding the Landscape of Cancer Biomarkers and Therapeutics." International Journal of Molecular Sciences 21, no. 23 (2020): 9032. http://dx.doi.org/10.3390/ijms21239032.

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Alternative splicing (AS) is a critical post-transcriptional regulatory mechanism used by more than 95% of transcribed human genes and responsible for structural transcript variation and proteome diversity. In the past decade, genome-wide transcriptome sequencing has revealed that AS is tightly regulated in a tissue- and developmental stage-specific manner, and also frequently dysregulated in multiple human cancer types. It is currently recognized that splicing defects, including genetic alterations in the spliced gene, altered expression of both core components or regulators of the precursor

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Song, Xiaowei, Zhenyu Zeng, Huanhuan Wei, and Zefeng Wang. "Alternative splicing in cancers: From aberrant regulation to new therapeutics." Seminars in Cell & Developmental Biology 75 (March 2018): 13–22. http://dx.doi.org/10.1016/j.semcdb.2017.09.018.

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Camino, Linda, and Kaja Finkler. "Spiritualist Healers in Mexico: Successes and Failures of Alternative Therapeutics." Journal of American Folklore 101, no. 399 (1988): 121. http://dx.doi.org/10.2307/540283.

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Alba, Annia, Carlos López-Abarrategui, and Anselmo J. Otero-González. "Host defense peptides: An alternative as antiinfective and immunomodulatory therapeutics." Biopolymers 98, no. 4 (2012): 251–67. http://dx.doi.org/10.1002/bip.22076.

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Ruiz Reyes, Dionis, Maikro Osvaldo Chávez Moya, Ileana Beatriz Quiroga López, and Adriel Herrero Díaz. "Stem cells, regenerating medical therapeutics." Interdisciplinary Rehabilitation / Rehabilitacion Interdisciplinaria 6 (January 1, 2026): 181. https://doi.org/10.56294/ri2026181.

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Introduction: Regenerative medicine aims to stimulate or regenerate cells, tissues, or organs to restore or establish normal function. Among its approaches, stem cell therapy has undoubtedly made the most progress. Its use constitutes a novel therapeutic alternative for diseases treated by diverse medical specialties, not least the recent COVID-19 caused by the SARS-CoV-2 virus.Objective: To describe the application of stem cell therapy in different medical specialties and in the treatment and rehabilitation of COVID-19-positive patients.Method: A literature review was conducted, consulting or

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Quazi, Mohzibudin Z., Jimin Hwang, Youngseo Song, and Nokyoung Park. "Hydrogel-Based Biosensors for Effective Therapeutics." Gels 9, no. 7 (2023): 545. http://dx.doi.org/10.3390/gels9070545.

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Nanotechnology and polymer engineering are navigating toward new developments to control and overcome complex problems. In the last few decades, polymer engineering has received researchers’ attention and similarly, polymeric network-engineered structures have been vastly studied. Prior to therapeutic application, early and rapid detection analyses are critical. Therefore, developing hydrogel-based sensors to manage the acute expression of diseases and malignancies to devise therapeutic approaches demands advanced nanoengineering. However, nano-therapeutics have emerged as an alternative appro

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Hazel, Karl, and Anthony O’Connor. "Emerging treatments for inflammatory bowel disease." Therapeutic Advances in Chronic Disease 11 (January 2020): 204062231989929. http://dx.doi.org/10.1177/2040622319899297.

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Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammation, a relapsing and remitting clinical course, requirement for lifelong medication and often, significant morbidity. While multiple effective therapeutic options exist for the treatment of IBD, a proportion of patients will either fail to respond or lose response to therapy. Advances in therapeutics, such as the gut-specific anti-integrins, now offer patients an alternative option to systemic immunosuppression. Anti-interleukin 12 (anti-IL-12)/IL-23 agents offer n

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Ernst, E. "The Washington Manual of Medical Therapeutics." Focus on Alternative and Complementary Therapies 7, no. 1 (2010): 68–69. http://dx.doi.org/10.1111/j.2042-7166.2002.tb03343.x.

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Togliatto, Gabriele, Patrizia Dentelli, and Maria Felice Brizzi. "Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications." Journal of Diabetes Research 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/373708.

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Vascular complications are major causes of morbidity and mortality in type 2 diabetes patients. Mitochondrial reactive oxygen species (ROS) generation and a lack of efficient antioxidant machinery, a result of hyperglycaemia, mainly contribute to this problem. Although advances in therapy have significantly reduced both morbidity and mortality in diabetic individuals, diabetes-associated vascular complications are still one of the most challenging health problems worldwide. New healing options are urgently needed as current therapeutics are failing to improve long-term outcomes. Particular eff

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Gupta, PD. "Menstrual Blood Mesenchymal Stem Cells: Boon in Therapeutics." Biotechnology and Bioprocessing 2, no. 4 (2021): 01–06. http://dx.doi.org/10.31579/2766-2314/032.

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Stem cell therapy gained momentum for the past three decades in therapeutics. Alternative strategies are indispensable for the treatment of many diseases in the present scenario due to side effects of synthetic chemicals as drugs. Mesenchymal cells of different origin have been in use with good results, though ethical issues and limited availability is a drawback. Novel menstrual blood mesenchymal stems cells prove to be a wealth out of waste is a boon in therapeutics. In this review we bring a bird’s eye view of different diseases treated with menstrual blood mesenchymal stem cells with posit

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Immadi Siva Ratnakar. "Phage Therapy: Challenges and Opportunities." Fine Focus 8, no. 1 (2022): 12–35. http://dx.doi.org/10.33043/ff.8.1.12-35.

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The development of antibiotic resistance in bacteria is a growing concern. This situation demands a search for antibiotic alternatives. Bacteriophages—natural viral predators of bacteria—are viewed as a possible alternative to treat bacterial infections. Many clinical trials today have not found phages effective as therapeutics. Some of the major challenges regarding usage of bacteriophage as a therapeutic have been: horizontal evolution of bacteria, limited host range of bacteriophage, removal of endotoxins in preparations, the technical feasibility of isolation, mode of administration, rapid

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Parvin, Nargish, Tapas K. Mandal, and Sang-Woo Joo. "The Impact of COVID-19 on RNA Therapeutics: A Surge in Lipid Nanoparticles and Alternative Delivery Systems." Pharmaceutics 16, no. 11 (2024): 1366. http://dx.doi.org/10.3390/pharmaceutics16111366.

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The COVID-19 pandemic has significantly accelerated progress in RNA-based therapeutics, particularly through the successful development and global rollout of mRNA vaccines. This review delves into the transformative impact of the pandemic on RNA therapeutics, with a strong focus on lipid nanoparticles (LNPs) as a pivotal delivery platform. LNPs have proven to be critical in enhancing the stability, bioavailability, and targeted delivery of mRNA, facilitating the unprecedented success of vaccines like those developed by Pfizer-BioNTech and Moderna. Beyond vaccines, LNP technology is being explo

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Mukharji, Projit Bihari. "Dis-locating Subaltern Therapeutics." Asian Medicine 13, no. 1-2 (2018): 134–69. http://dx.doi.org/10.1163/15734218-12341411.

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AbstractThe article is about totka chikitsha, a particular type of subaltern therapeutics widely recognized in northern and eastern South Asia. These simple recipes often circulated through transient encounters, physical or mediatized, between strangers. During the colonial era, government employment and the traveling that it required made many Bengalis in clerical jobs particularly authoritative in totka therapeutics. Though this mode of therapy was seen as an alternative to the increasingly commoditized medical market, anticonsumerism also became a discursive frame within which certain secti

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Trucillo, Paolo. "Advances in Drug Delivery System Designs and Therapeutics." Processes 13, no. 4 (2025): 1176. https://doi.org/10.3390/pr13041176.

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Vlaeminck, Jelle, Dina Raafat, Kristin Surmann, et al. "Exploring Virulence Factors and Alternative Therapies against Staphylococcus aureus Pneumonia." Toxins 12, no. 11 (2020): 721. http://dx.doi.org/10.3390/toxins12110721.

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Pneumonia is an acute pulmonary infection associated with high mortality and an immense financial burden on healthcare systems. Staphylococcus aureus is an opportunistic pathogen capable of inducing S. aureus pneumonia (SAP), with some lineages also showing multidrug resistance. Given the high level of antibiotic resistance, much research has been focused on targeting S. aureus virulence factors, including toxins and biofilm-associated proteins, in an attempt to develop effective SAP therapeutics. Despite several promising leads, many hurdles still remain for S. aureus vaccine research. Here,

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Mir, Rakeeb Ahmad, Anshika Tyagi, Sofi Javed Hussain, et al. "Saffron, a Potential Bridge between Nutrition and Disease Therapeutics: Global Health Challenges and Therapeutic Opportunities." Plants 13, no. 11 (2024): 1467. http://dx.doi.org/10.3390/plants13111467.

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Plants are an important source of essential bioactive compounds that not only have a beneficial role in human health and nutrition but also act as drivers for shaping gut microbiome. However, the mechanism of their functional attributes is not fully understood despite their significance. One such important plant is Crocus sativus, also known as saffron, which possesses huge medicinal, nutritional, and industrial applications like food and cosmetics. The importance of this plant is grossly attributed to its incredible bioactive constituents such as crocins, crocetin, safranal, picrocrocin, and

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Pipe, Steven W. "Hemophilia: New Protein Therapeutics." Hematology 2010, no. 1 (2010): 203–9. http://dx.doi.org/10.1182/asheducation-2010.1.203.

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Abstract Therapeutic advances for patients with hemophilia have resulted in reduced mortality, improved joint outcomes, safety from blood-transmitted pathogens, improved quality of life, and a normalized life span in the developed world. The production of recombinant coagulation factors has increased the worldwide capacity for replacement therapy and facilitated aggressive prophylactic therapy. However, this has come at significant cost, and barriers remain to broad application of prophylaxis. Recombinant DNA technology remains a promising platform to develop novel hemophilia therapeutics with

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Lu, Lunjie, Jun Zhou, Jingying Zhang, Jun Che, Yang Jiao, and Yusong Zhang. "Prevention and Therapeutic Effects and Mechanisms of Tanshinone IIA Sodium Sulfonate on Acute Liver Injury Mice Model." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/4097398.

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Tanshinone IIA sodium sulfonate (TSS) is a water-soluble derivative of tanshinone IIA, which is the main pharmacologically active component of Salvia miltiorrhiza. This study aimed to verify the preventive and therapeutic effects of TSS and its combined therapeutic effects with magnesium isoglycyrrhizinate (MI) in D-galactosamine- (D-Gal-) induced acute liver injury (ALI) in mice. The potential regulatory mechanisms of TSS on ALI were also examined. Our results may provide a basis for the development of novel therapeutics for ALI.

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Stephens, Deborah M., and John C. Byrd. "How I manage ibrutinib intolerance and complications in patients with chronic lymphocytic leukemia." Blood 133, no. 12 (2019): 1298–307. http://dx.doi.org/10.1182/blood-2018-11-846808.

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Abstract Chronic lymphocytic leukemia (CLL) therapy has changed dramatically with the introduction of several targeted therapeutics. Ibrutinib was the first approved for use in 2014 and now is used for initial and salvage therapy of CLL patients. With its widespread use in clinical practice, ibrutinib’s common and uncommon adverse events reported less frequently in earlier clinical trials have been experienced more frequently in real-world practice. In particular, atrial fibrillation, bleeding, infections, and arthralgias have been reported. The management of ibrutinib’s adverse events often c

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Singh, Swati, and Matthew J. Smith. "RAS GTPase signalling to alternative effector pathways." Biochemical Society Transactions 48, no. 5 (2020): 2241–52. http://dx.doi.org/10.1042/bst20200506.

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RAS GTPases are fundamental regulators of development and drivers of an extraordinary number of human cancers. RAS oncoproteins constitutively signal through downstream effector proteins, triggering cancer initiation, progression and metastasis. In the absence of targeted therapeutics to mutant RAS itself, inhibitors of downstream pathways controlled by the effector kinases RAF and PI3K have become tools in the treatment of RAS-driven tumours. Unfortunately, the efficacy of this approach has been greatly minimized by the prevalence of acquired drug resistance. Decades of research have establis

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Ruigrok, Vincent J. B., Mark Levisson, Michel H. M. Eppink, Hauke Smidt, and John van der Oost. "Alternative affinity tools: more attractive than antibodies?" Biochemical Journal 436, no. 1 (2011): 1–13. http://dx.doi.org/10.1042/bj20101860.

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Antibodies are the most successful affinity tools used today, in both fundamental and applied research (diagnostics, purification and therapeutics). Nonetheless, antibodies do have their limitations, including high production costs and low stability. Alternative affinity tools based on nucleic acids (aptamers), polypeptides (engineered binding proteins) and inorganic matrices (molecular imprinted polymers) have received considerable attention. A major advantage of these alternatives concerns the efficient (microbial) production and in vitro selection procedures. The latter approach allows for

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Schneider, Jay S. "GM1 Ganglioside as a Disease-Modifying Therapeutic for Parkinson’s Disease: A Multi-Functional Glycosphingolipid That Targets Multiple Parkinson’s Disease-Relevant Pathogenic Mechanisms." International Journal of Molecular Sciences 24, no. 11 (2023): 9183. http://dx.doi.org/10.3390/ijms24119183.

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Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting millions of patients worldwide. Many therapeutics are available for treating PD symptoms but there is no disease-modifying therapeutic that has been unequivocally shown to slow or stop the progression of the disease. There are several factors contributing to the failure of many putative disease-modifying agents in clinical trials and these include the choice of patients and clinical trial designs for disease modification trials. Perhaps more important, however, is the choice of therapeutic, which for the most part,

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Meir, Michal, and Daniel Barkan. "Alternative and Experimental Therapies of Mycobacterium abscessus Infections." International Journal of Molecular Sciences 21, no. 18 (2020): 6793. http://dx.doi.org/10.3390/ijms21186793.

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Mycobacterium abscessus is a non-tuberculous mycobacterium notoriously known for causing severe, chronic infections. Treatment of these infections is challenging due to either intrinsic or acquired resistance of M. abscessus to multiple antibiotics. Despite prolonged poly-antimicrobial therapy, treatment of M. abscessus infections often fails, leading to progressive morbidity and eventual mortality. Great research efforts are invested in finding new therapeutic options for M. abscessus. Clofazimine and rifabutin are known anti-mycobacterial antibiotics, repurposed for use against M. abscessus.

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Ruan, Ying-dan. "Summarization of constipation treated with Tuina therapeutics." Journal of Acupuncture and Tuina Science 6, no. 1 (2008): 62–64. http://dx.doi.org/10.1007/s11726-008-0062-8.

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Oschman, James, and Lisa Tully. "Energy Medicine in Therapeutics and Human Performance." Journal of Alternative and Complementary Medicine 10, no. 2 (2004): 418. http://dx.doi.org/10.1089/107555304323062464.

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Kotecha, Rupesh, Raees Tonse, Haley Appel, et al. "Regression of Intracranial Meningiomas Following Treatment with Cabozantinib." Current Oncology 28, no. 2 (2021): 1537–43. http://dx.doi.org/10.3390/curroncol28020145.

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Recurrent meningiomas remain a substantial treatment challenge given the lack of effective therapeutic options aside from surgery and radiation therapy, which yield limited results in the retreatment situation. Systemic therapies have little effect, and responses are rare; the search for effective systemic therapeutics remains elusive. In this case report, we provide data regarding significant responses in two radiographically diagnosed intracranial meningiomas in a patient with concurrent thyroid carcinoma treated with cabozantinib, an oral multitarget tyrosine kinase inhibitor with potent ac

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Upadhyay, Harish C. "Medicinal Chemistry of Alternative Therapeutics: Novelty and Hopes with Genus Ammannia." Current Topics in Medicinal Chemistry 19, no. 10 (2019): 784–94. http://dx.doi.org/10.2174/1568026619666190412101047.

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The plants have formed the basis of folklore remedy since the beginning of human civilization. The cumulative human endeavor and experience over a period of thousands of years developed into well to organize traditional medicine systems viz. Ayurvedic, Unani, Chinese amongst others. Across the world, traditional medicine is either the mainstay of health care or serves as a complement to modern drugs. In view of worldwide use of traditional medicines, World Health Organization launched ‘WHO-Traditional Medicine Strategy 2014-2023’ for the development of strong policies regarding knowledge-base,

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Jones, Jennifer, Craig P. Murphy, Roy D. Sleator, and Eamonn P. Culligan. "The urobiome, urinary tract infections, and the need for alternative therapeutics." Microbial Pathogenesis 161 (December 2021): 105295. http://dx.doi.org/10.1016/j.micpath.2021.105295.

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Bougea, Anastasia, Christos Koros, Athina-Maria Simitsi, Chrysa Chrysovitsanou, Athanasios Leonardos, and Leonidas Stefanis. "Medical cannabis as an alternative therapeutics for Parkinsons’ disease: Systematic review." Complementary Therapies in Clinical Practice 39 (May 2020): 101154. http://dx.doi.org/10.1016/j.ctcp.2020.101154.

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Lewis, Colin. "Book Review: Acupuncture Therapeutics." Acupuncture in Medicine 29, no. 2 (2011): 160. http://dx.doi.org/10.1136/acupmed-2011-010019.

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Jenkins, Timothy, Thomas Fryer, Rasmus Dehli, et al. "Toxin Neutralization Using Alternative Binding Proteins." Toxins 11, no. 1 (2019): 53. http://dx.doi.org/10.3390/toxins11010053.

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Animal toxins present a major threat to human health worldwide, predominantly through snakebite envenomings, which are responsible for over 100,000 deaths each year. To date, the only available treatment against snakebite envenoming is plasma-derived antivenom. However, despite being key to limiting morbidity and mortality among snakebite victims, current antivenoms suffer from several drawbacks, such as immunogenicity and high cost of production. Consequently, avenues for improving envenoming therapy, such as the discovery of toxin-sequestering monoclonal antibodies against medically importan

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