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Articles de revues sur le sujet « American Institute of Park Executives »

Auteur : Grafiati

Publié le 25 juillet 2024

Mis à jour le 31 juillet 2025

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1

Cavalcanti, Araujo. "A Presença do Brasil no II congresso Ibero-Americano de municípios." Revista do Serviço Público 86, no. 3 (2019): 191–203. http://dx.doi.org/10.21874/rsp.v86i3.3656.

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Dentre os fatores determinantes do sucesso obtido, destacam-se a extraordinária capacidade organizadora e a eficiente atuação da Comissão Executiva do Congresso, integrada pelas figuras exponenciais do Conde de Mayalde, Alcaide de Madri, do Prof. Dom Carlos Ruiz dei Castillo, Presidente do Instituto Espanhol de Estudos de Administração Local, de Madri; do Prof. Marcelo Caetano, eminente catedrático e jurisconsulto; do Brigadeiro França Borges, Presidente da Câmara Municipal de Lisboa; do Doutor Macedo de Barros, Secretário Executivo do certame, para citar apenas algumas personalidades da mais

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Abdolmohammadi, Mohammad J. "Chief Audit Executives' Assessment of Internal Auditors' Performance Attributes by Professional Rank and Cultural Cluster." Behavioral Research in Accounting 24, no. 1 (2011): 1–23. http://dx.doi.org/10.2308/bria-50023.

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ABSTRACT This study explores chief audit executives' perceptions of the most important performance attributes of internal auditors by professional rank and cultural cluster. A large sample of chief audit executives (CAEs) from 19 countries located in five different cultural clusters was surveyed by the Institute of Internal Auditors Research Foundation (CBOK 2006). Analysis of data generated by that survey indicates that while leadership attributes (e.g., negotiating) are perceived to be most important for upper ranks in internal auditing, technical skills (e.g., analytical) are most important

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Mitchell, Russ. "President's Message." Journal of System Safety 55, no. 3 (2020): 2. http://dx.doi.org/10.56094/jss.v55i3.33.

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It’s the new year, a new decade, and we’ve turned the page as an organization. We’ve completed our contracting process and have a new staff! We’ve contracted with Ewald Consulting to provide association management services. Under this new arrangement, we will benefit by having professional staff available to help plan our annual Conference and events, provide enhanced member services and assist the Society’s leadership in moving strategic initiatives forward. Ewald Consulting is charter accredited by the Association Management Companies Institute (AMC Institute) and charter certified by

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Cooper, Priscilla Hancock. "A City Embraces Its Past, Looks to the Future." Public Historian 40, no. 3 (2018): 211–31. http://dx.doi.org/10.1525/tph.2018.40.3.211.

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The Birmingham Civil Rights Institute marks its twenty-fifth year as the focal point for the city’s civil rights district. Inspired by the vision of Mayor David Vann, it became a reality under the leadership of the Dr. Richard Arrington, the city’s first African American mayor. A team of committed community volunteers led the institute through thirteen years of development in spite of corporate skepticism and citizen resistance. BCRI evolved as a model for staff development, community engagement and leadership and is now a key partner in the Birmingham Civil Rights National Monument, a unit of

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Yamashita, Samuel H. "The “Japanese Turn” in Art, Architecture, and Cuisine in Europe and the United States, 1860–2020." Journal of Japanese Studies 51, no. 1 (2025): 41–78. https://doi.org/10.1525/jjs.2025.51.1.41.

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Over the last forty years, Japanese cuisine has had an oversized influence on fine dining in the United States. Chefs cooking at celebrated American restaurants are now freely using Japanese ingredients, condiments, culinary techniques, and concepts, and the Culinary Institute of America in Hyde Park, New York, the leading culinary school in the country, now offers a concentration in Japanese cuisine. This article examines this “Japanese turn” and argues that this contemporary culinary movement toward Japan is comparable to the Japanese influence on European and American art and architecture i

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Robl, Fabiane, Paulo Eduardo Dias de Mello, Claudia Sapag Ricci, and Claisy Marinho-Araújo. "Stela Maria Meneghel." Revista História Hoje 4, no. 7 (2015): 183. http://dx.doi.org/10.20949/rhhj.v4i7.169.

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A entrevista discute o processo de Avaliação da Educação Superior no Brasil, sobretudo a história da criação da Comissão Especial de Avaliação (CEA) e da Comissão Nacional de Avaliação da Educação Superior (Conaes), além de problematizar a formulação das políticas de avaliação. Stela Maria Meneghelé Coordenadora Geral de Controle de Qualidade da Educação Superior da Diretoria de Avaliação da Educação Superior (Daes) do Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (Inep). Bacharel e licenciada em Letras (1987), mestre em Educação (1994) e doutora (2001) pela Universida

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Berwanger, Otavio. "ANTICOAGULANTES ORAIS DIRETOS EM PACIENTES COM DOENÇA VALVAR: A CONTRIBUIÇÃO DO ESTUDO RIVER." Revista da Sociedade de Cardiologia do Estado de São Paulo 31, no. 4 (2021): 455–58. http://dx.doi.org/10.29381/0103-8559/20213104455-8.

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POR QUE DISCUTIR O ESTUDO RIVER? Como Presidente do Comitê Executivo do estudo RIVER, é um prazer discutir os resultados deste ensaio clínico randomizado,100% brasileiro, apresentado na sessão de Late Breaking Clinical Trials do congresso da American Heart Association (AHA) 2020. Os resultados principais foram publicados no New England Journal of Medicine , o que demonstra a força e a maturidade da cardiologia brasileira em gerar resultados com impacto clínico internacional. O estudo RIVER avaliou o tratamento com rivaroxabana em pacientes com fibrilação atrial e bioprótese mitral. Este foi um

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Betchkal, Davyd H. "Plumb-full of hush to the Brim: Park sound levels per American National Standards Institute S12.100-2014." Journal of the Acoustical Society of America 150, no. 4 (2021): A100. http://dx.doi.org/10.1121/10.0007759.

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Marzano, Annalisa. "Preserving cultural heritage and developing a modern city: the difficult case of Euesperides." Libyan Studies 37 (2006): 89–93. http://dx.doi.org/10.1017/s0263718900004040.

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AbstractThis note reports on a paper presented at the American Institute of Archaeology 107th Annual Meeting (Montreal January 2006). The theme of the American Institute of Archaeology Annual meeting was ‘Management and Preservation of Cultural Heritage’. The Euesperides Project presented a paper on Euesperides (Sidi Abeid, Benghazi), the Archaic Greek settlement founded in the sixth century BC. Although the site was declared a protected area for its historical and archaeological importance, it still lacks effective protection. The site, important also from a naturalistic point of view, is use

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Seleb, David J., and Jodi Kolo. "Our Path to Engagement, Learning, and Stewardship: The Oak Park Public Library, the American Library Association, and the Harwood Institute." Public Library Quarterly 36, no. 2 (2017): 123–35. http://dx.doi.org/10.1080/01616846.2017.1312194.

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Belanger, Patrick. "California Condors, Source Credibility, and Wildlife Conservation Messaging." Journalism and Media 3, no. 3 (2022): 419–35. http://dx.doi.org/10.3390/journalmedia3030030.

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This article examines the role of source credibility in the sphere of wildlife conservation campaigns. Specifically, it explores how particular messengers can motivate hunters, ranchers, and wildlife managers in California, Utah, and Arizona to voluntarily adopt non-lead ammunition. I analyze two partner websites, each designed to provide the hunting community with accurate information about non-lead ammunition. I then identify key principles regarding source credibility that arose from semi-structured interviews with four individuals closely involved in North American vulture and raptor conse

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Brown, Marisa, Nathanael Vlachos, Anthony Marshall, Karen Butner, and Laura Clymer. "Beyond closed doors: How to leverage open innovation ecosystems for supply chain success." Journal of Supply Chain Management, Logistics and Procurement 7, no. 3 (2025): 222. https://doi.org/10.69554/eiqy1501.

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This paper makes the case for open innovation as an approach that can drive significant value for supply chain organisations. In contrast to traditional innovation, which tends to unfold behind closed doors, open innovation leads to new products, services and operating models as the result of collaboration and co-creation between an organisation and its partners. Drawing from survey research of 1,100 C-suite executives carried out by the American Productivity & Quality Center and the IBM Institute for Business Value (IBV), the paper explores leading practices for how organisations can: 1)

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Tobar, Felipe Bertazzo, Ilanil Coelho, and Luana de Carvalho Silva Gusso. "Quando se mistura futebol e política." FuLiA / UFMG 5, no. 2 (2021): 158–81. http://dx.doi.org/10.35699/2526-4494.2020.21991.

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O artigo tem por objetivo discutir a relação entre futebol e política a partir do estudo do processo de tombamento da sede social do America Football Club (RJ). Mediante pesquisa sobre a história do clube, análise de reportagens da imprensa e do estudo da legislação, discutem-se os atos de tombamento da sede social, realizados no início da década de 2010, pela lavra discricionária do poder executivo municipal. Com base na teoria geral dos campos sociais de Bourdieu, buscou-se responder como e por que agentes políticos, provocados por dirigentes futebolísticos, apropriaram-se deste instrumento

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Goodrich, Erin L., and Julie L. Webb. "Complete Blood Count and Biochemistry Reference Intervals for Healthy Adult Donkeys in the United States." Animals 14, no. 14 (2024): 2018. http://dx.doi.org/10.3390/ani14142018.

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Previous hematologic and serum biochemistry reference interval (RI) values have been established for donkeys in various geographic regions, life-stages, or for specific donkey breeds. The last extensive investigation establishing RIs for adult donkeys in the United States (U.S.) was published over three decades ago. We aimed to establish updated robust RIs using a reference population of apparently healthy adult donkeys from across the U.S. Standard sized (n = 102), miniature (n = 17), and mammoth (n = 1) donkeys from four different states were enrolled, with 20% of the study population includ

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Hernández, Gerardo, and Carlos-Alfonso Romero-Arias. "La Guardia Nacional y la militarización de la seguridad pública en México/ The National Guard and the militarization of public security in Mexico." URVIO. Revista Latinoamericana de Estudios de Seguridad, no. 25 (November 27, 2019): 87–106. http://dx.doi.org/10.17141/urvio.25.2019.3995.

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La amenaza que representa la inseguridad pública en América Latina ha conllevado que muchos de los gobiernos asolados por ella recurran a las políticas de militarización. En el caso de México, el gobierno creó la Guardia Nacional para pacificar el país. El objetivo del artículo es responder la pregunta ¿por qué, pese a los argumentos y posturas de diferentes actores nacionales e internacionales, la Administración Federal en México (2018-2024) decidió crear una Guardia Nacional para combatir y reducir los índices de violencia? El estudio emplea un método explicativo y utiliza información del Ba

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Reina Ortiz, Miquel, Mario Santana Quintero, Clemencia Vernaza, Patricia Ramírez, Fernando Montejo Gaitán, and Juana Segura Escobar. "Capacity building for the documentation and conservation of Latin American cultural heritage: making technology accessible and sustainable." Journal of Cultural Heritage Management and Sustainable Development 11, no. 2 (2021): 155–69. http://dx.doi.org/10.1108/jchmsd-05-2020-0076.

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PurposeThe purpose of this contribution is to demonstrate the importance of interdisciplinary collaboration in integrating advanced and emerging digital techniques in the appropriate and sustainable documentation of heritage sites in Latin America. Existing collaboration between the Universidad del Externado de Colombia, the Colombian Institute of Anthropology and History and the Carleton Immersive Media Studio of Carleton University in Ottawa (Canada) have been sued to demonstrate the importance of this approach. The described collaboration allowed a team of students, researchers, government

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Hamidi, Shima, Roya Etminani-Ghasrodashti, Sanggyun Kang, and Reid Ewing. "Institute of Transportation Engineers Guidelines versus Actual Trip and Parking Generation for a Transit-Oriented Development in an Auto-Oriented Region." Transportation Research Record: Journal of the Transportation Research Board 2674, no. 10 (2020): 917–26. http://dx.doi.org/10.1177/0361198120935112.

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The Institute of Transportation Engineers (ITE) guidelines serve as the most widely used reference for trip and parking generation estimates for any new development in the U.S.A. However, recent empirical studies question the efficacy of ITE guidelines in forecasting trip and parking generation in transit-oriented developments (TODs). Following the methodology of studies on seven TODs across the U.S.A., this study focuses on Dallas (TX), as a more auto-oriented American city, to explore the trip and parking generation at Mockingbird TOD. It finds that, with the exception of Station Park in Sal

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Hendra Fahruddin Siregar, Dadang Subarna, Melly Andriana, M, and Ali Tami Purba. "Analysis of the Building Structure for Mixed-Use Al-Amin Living Lab and Industrial Park in Sampe Cita Village, Kutalimbaru District." International Conference on Education, Social Sciences and Technology (ICESST) 3, no. 1 (2024): 123–32. https://doi.org/10.55606/icesst.v3i1.402.

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A mixed-use building refers to the combination of several different functions in one building, such as residential, office, shopping, and recreational functions built on one site. Designing the structure of a mixed-use building requires careful planning and consideration of various factors such as functional needs, aesthetics, and energy conservation. Additionally, the design of mixed-use buildings includes various functions in one area. The floor slabs and roofs use plain reinforcing steel with a strength of Fy = 240 MPa (Ø8mm). Concrete cover is taken as 20 mm. The design results in several

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Farmer, Kristine, Jeff Allen, Malak Khader, Tara Zimmerman, and Peter Johnstone. "Paralegal Students’ and Paralegal Instructors’ Perceptions of Synchronous and Asynchronous Online Paralegal Course Effectiveness: A Comparative Study." International Journal for Educational and Vocational Studies 3, no. 1 (2021): 1. http://dx.doi.org/10.29103/ijevs.v3i1.3550.

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To improve online learning pedagogy within the field of paralegal education, this study investigated how paralegal students and paralegal instructors perceived the effectiveness of synchronous and asynchronous online paralegal courses. This study intended to inform paralegal instructors and course developers how to better design, deliver, and evaluate effective online course instruction in the field of paralegal studies.Survey results were analyzed using independent samples t-test and correlational analysis, and indicated that overall, paralegal students and paralegal instructors positively pe

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Thorp, D. B. "CRAIG D. ATWOOD. Community of the Cross: Moravian Piety in Colonial Bethlehem. (Max Kade German-American Research Institute Series.) University Park: Pennsylvania State University Press. 2004. Pp. xi, 283. $37.50." American Historical Review 111, no. 1 (2006): 154–55. http://dx.doi.org/10.1086/ahr.111.1.154.

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Freitas, Edimilson Martins de, Larissa Cavalcanti Monteiro, Michelle Bonfim da Silva Fernandes, Hercílio Martelli Junior, Paulo Rogério Ferreti Bonan, and Sergio Avelino Mota Nobre. "Antifungal Susceptibility In Vitro Determined by the Etest(r) for Candida Obtained from the Oral Cavity of Irradiated and Elderly Individuals." Brazilian Dental Journal 26, no. 2 (2015): 99–104. http://dx.doi.org/10.1590/0103-6440201300115.

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This study aimed to evaluate the in vitro antifungal susceptibility of Candida species of head-and-neck-irradiated patients (Group 1), non-institutionalized (Group 2) and institutionalized elders (Group 3) using Etest(r) methodology. Candida was isolated from saliva and presumptively identified by CHROMagar Candida(r), confirmed by morphological criteria, carbohydrate assimilation (API 20C AUX(r)) and genetic typing (OPE 18). The collection was made from 29, 34 and 29 individuals (Groups 1, 2 and 3, respectively) with 67 isolates. Etest(r) strips (ketoconazole, itraconazole, fluconazole, ampho

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Wolf, Stephanie Grauman. "Rosalind J. Beiler . Immigrant and Entrepreneur: The Atlantic World of Caspar Wistar, 1650–1750.(Max Kade German‐American Research Institute Series.)University Park : Pennsylvania State University Press . 2008 . Pp. xii, 208. $55.00." American Historical Review 115, no. 1 (2010): 213–14. http://dx.doi.org/10.1086/ahr.115.1.213.

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Arana-Yi, C., A. W. Block, S. N. Sait, L. A. Ford, M. Barcos, and M. R. Baer. "Therapy-related myelodysplastic syndrome (t-MDS) following treatment of acute myeloid leukemia (AML)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 17509. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.17509.

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17509 Background: t-MDS is well described following treatment of lymphomas, solid tumors and acute promyelocytic leukemia. In contrast, it has been reported only rarely following treatment of AML, possibly because of the smaller percentage of long-term survivors or the difficulty of distinguishing t-MDS from AML relapse. Methods: Roswell Park Cancer Institute (RPCI) patients with a diagnosis of MDS by French-American-British or World Health Organization criteria following a diagnosis of AML were retrospectively reviewed. Results: Five adult patients treated for de novo AML between 1996 and 200

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Engel, Katherine Carté. "Ethnographies and Exchanges: Native Americans, Moravians, and Catholics in Early North America. Edited by A. G. Roeber. Max Kade German-American Research Institute Series. University Park: Pennsylvania State University Press, 2008. xxiv + 217pp. $45.00 cloth." Church History 78, no. 2 (2009): 411–13. http://dx.doi.org/10.1017/s0009640709000687.

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Jin, Haomiao, Doerte U. Junghaenel, Bart Orriens, Pey-Jiuan Lee, and Stefan Schneider. "Developing Early Markers of Cognitive Decline and Dementia Derived From Survey Response Behaviors: Protocol for Analyses of Preexisting Large-scale Longitudinal Data." JMIR Research Protocols 12 (February 21, 2023): e44627. http://dx.doi.org/10.2196/44627.

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Background Accumulating evidence shows that subtle alterations in daily functioning are among the earliest and strongest signals that predict cognitive decline and dementia. A survey is a small slice of everyday functioning; nevertheless, completing a survey is a complex and cognitively demanding task that requires attention, working memory, executive functioning, and short- and long-term memory. Examining older people’s survey response behaviors, which focus on how respondents complete surveys irrespective of the content being sought by the questions, may represent a valuable but often neglec

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Lee, Junho, Daehwan Lee, Kiwon Lee, et al. "Abstract 7430: Multicenter study on an artificial intelligence model for predicting NSCLC recurrence." Cancer Research 85, no. 8_Supplement_1 (2025): 7430. https://doi.org/10.1158/1538-7445.am2025-7430.

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Abstract Background: Accurate and practical prediction of recurrence in early-stage NSCLC is essential for managing patient outcomes and tailoring personalized treatment strategies. This study updated and validated a previously developed transformer-based model for NSCLC recurrence prediction, which integrates clinical, pathological, laboratory, and radiologic data, while proposing strategies to enhance its generalizability. Methods: The model was developed and internally validated using data from Samsung Medical Center (SMC) and Kyung Hee University Hospital (KH) collected from 2008 to 2024.

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Gupta, B., S. N. Sait, A. W. Block, L. A. Ford, K. B. Moysich, and M. R. Baer. "Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) following treatment for ovarian cancer." Journal of Clinical Oncology 25, no. 18_suppl (2007): 17506. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.17506.

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17506 Background: Therapy-related AML (t-AML) has been reported in ovarian cancer patients treated with chemotherapy and has been associated with the use of platinum. However, little is known about these patients’ clinical characteristics, cytogenetic changes, clinical course or treatment outcome. Methods: Roswell Park Cancer Institute patients with diagnoses of AML or MDS by French-American- British (FAB) Group or World Health Organization criteria following a diagnosis of ovarian cancer were retrospectively reviewed. Results: Ten patients were identified between 1990 and 2006. All 10 had rec

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Padmanabhan, A., A. Block, S. Sait, et al. "Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) following a diagnosis of breast cancer." Journal of Clinical Oncology 25, no. 18_suppl (2007): 7051. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.7051.

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7051 Background: Increasing use of chemotherapy and radiation therapy in breast cancer patients in the adjuvant setting heightens concern about therapy-related AML and MDS. Little is known about the characteristics of these disorders following breast cancer. Methods: Roswell Park Cancer Institute (RPCI) patients with diagnoses of MDS or AML by French-American-British Group or World Health Organization criteria following breast cancer were retrospectively reviewed. Results: 34 women were identified between 1983 and 2006. 10 (29%) were also diagnosed with additional malignancies, including non-H

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Davis, Evan W., Nisha M. Nair, Karen Hulme, Nancy Barone, Christine B. Ambrosone, and Rikki A. Cannioto. "Does adherence to cancer prevention guidelines before diagnosis associate with improved cancer survival?" Journal of Clinical Oncology 41, no. 16_suppl (2023): 10582. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.10582.

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10582 Background: The American Institute for Cancer Research and American Cancer Society regularly publish cancer prevention recommendations for decreasing cancer risk. Which lifestyles, or whether they work together to impact cancer survival is not well established. We examined associations of adherence to cancer prevention recommendations with mortality in 5,766 patients enrolled in the Data Bank and BioRepository at Roswell Park. Methods: Patients were newly diagnosed between 2003 and 2016 with a variety of pathologically confirmed invasive malignancies. Detailed epidemiological data includ

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Calkins, Hannah, Tatiana Shaurova, David W. Goodrich, Mukund Seshadri, Candace S. Johnson, and Pamela A. Hershberger. "Abstract 1093: BRD9 inhibition overcomes epithelial to mesenchymal transition (EMT)-associated tyrosine kinase inhibitor (TKI) tolerance in epidermal growth factor receptor (EGFR) mutant lung cancer." Cancer Research 82, no. 12_Supplement (2022): 1093. http://dx.doi.org/10.1158/1538-7445.am2022-1093.

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Abstract Advanced lung cancer patients that present with activating mutations in the epidermal growth factor receptor (EGFR) are treated with EGFR tyrosine kinase inhibitors (EGFR TKIs). While initially effective, all patients eventually develop therapeutic resistance and experience disease progression. Strategies to prevent EGFR TKI resistance are needed to improve patient outcomes. We chronically exposed H1975 cells (EGFR-L858R/T790M) to EGFR TKI osimertinib to study emergence of resistance. H1975 cells that were expanded under drug treatment (designated H1975OR) acquired an EMT phenotype an

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Kang, JinHo, Jee Hyun Choi, Min Ji Seo, et al. "Abstract 6331: The anti-tumor activity of HSP-90 therapeutic cancer vaccine (AST-021p) combine with TLR2/3 agonist in a MMTV-neu transgenic model." Cancer Research 83, no. 7_Supplement (2023): 6331. http://dx.doi.org/10.1158/1538-7445.am2023-6331.

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Abstract Background: AST-021p, which is derived from HLA class II binding epitopes of human HSP90 protein, is an investigational therapeutic cancer vaccine for the malignant neoplasms. AST-021p is designed to demonstrate the immunologic efficacy by activating antigen-specific CD4+ Th1 cell in humans. Due to their ability to link the innate with the adaptive immune response, Toll-like receptor (TLR) agonists are highly promising as adjuvants in vaccines against life-threatening and complex diseases such as cancer, AIDS and malaria. In this study, AST-021p was investigated to evaluate the immuno

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MONTEIRO, Espedito Saraiva, and Elisangela Alves da Silva SCAFF. "EDUCAÇÃO INTEGRAL OU CONTRATURNO ESCOLAR? concepções sobre o programa mais educação no município de Dourados-MS." Trama 14, no. 33 (2018): 118–29. http://dx.doi.org/10.48075/rt.v14i33.19302.

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Este artigo tem como objetivo analisar o processo de implementação do Programa Mais Educação na rede municipal pública de Dourados-MS, no período compreendido entre 2009 e 2015, com vistas a identificar e discutir a concepção de educação de tempo integral explicitada nesse processo. Para tanto, realizou-se pesquisa qualitativa, tendo como campo empírico as 45 escolas públicas municipais de Dourados – MS, utilizando como instrumento de coleta de dados questionário junto aos integrantes do Programa. Constata-se que a concepção de educação integral presente no Programa Mais Educação está relacion

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Aung, Fleur M., Benjamin Litchtiger, and Issa Khouri. "Comparison of HLA Alleles in Follicular Lymphoma and Chronic Lymphocytic Leukemia Patients Referred for Allogeneic Stem Cell Transplantation." Blood 120, no. 21 (2012): 4218. http://dx.doi.org/10.1182/blood.v120.21.4218.4218.

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Abstract Abstract 4218 Introduction: Data recently published showed that besides the several well-known parameters, long term outcome after allogeneic stem cell transplantation (SCT) in chronic lymphocytic leukemia (CLL) may be influenced by the presence or absence of certain HLA class I alleles (HLA-A1+/A2-/B44-) (Khouri et. Al. Cancer 2011). We have also recently published an 11-year progression free survival (PFS) rate of 72% in relapsed follicular lymphoma (FL) after SCT (Khouri et al. Blood 2012). A higher relapse rate has been observed in CLL patients when compared to FL (50% vs. 4%). Si

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Abrams, Corinne E. "Abstract A013: Advancing colorectal cancer outreach & screening strategies: Tailoring approaches for two-spirit and urban Native LGBTQIA2S+ populations." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): A013. http://dx.doi.org/10.1158/1538-7755.disp23-a013.

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Abstract Background: The focus of this one-year collaborative initiative between the Center for Indigenous Cancer Research at Roswell Park and Northwestern University’s Institute of Sexual and Gender Minority Health and Wellbeing is to refine and customize an existing colorectal cancer (CRC) screening program to suit the unique needs of Two-Spirit and Native American LGBTQ+ urban populations. This undertaking, grounded in exploratory and explanatory qualitative methodologies, is not intended to test a predefined hypothesis, but rather aims to learn, understand, and adapt based on community inp

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Seo, Jee-Woo, Jae-Yoon Kim, Ye-Jin Ha, et al. "Abstract 3356: Construction of a 23-gene risk scoring system to predict disease recurrence and chemotherapy response in mucinous colorectal cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 3356. https://doi.org/10.1158/1538-7445.am2025-3356.

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Abstract Backgrounds: Mucinous adenocarcinoma (MuC), a unique subtype of colorectal cancer (CRC), exhibits distinct molecular features and is associated with poorer outcomes compared to non-mucinous adenocarcinoma (NMuC). Standard CRC treatments often overlook the molecular diversity within CRC, especially in stage II, where the benefit of adjuvant chemotherapy remains debated. Biomarkers are needed to improve risk assessment and guide tailored treatments. Methods: We conducted molecular profiling of 259 CRC samples, including MuC and NMuC subtypes, to identify MuC-specific gene signatures. A

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Park, John M., and Michael G. Holliday. "Occupational-health Aspects of Marine Oil-spill Response." Pure and Applied Chemistry 71, no. 1 (1999): 113–33. http://dx.doi.org/10.1351/pac199971010113.

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Introduction: This chapter addresses chemical aspects of occupational health and marine oil-spill response and is restricted to exposures to crude oil in its various forms. Thus in-situ burning of oil is included, but ancillary chemicals such as surfactants or bioremediation agents are not. The content of this chapter is largely based on the literature published after 1985, the date of a comprehensive review conducted by Politzer et al. [1985] for the American Petroleum Institute, and on a review carried out for the Marine Spill Response Corporation early in 1993 [Holliday and Park, 1993].Conc

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Park, Margaret A., Somashekar G. Krishna, Maria C. Genilo-Delgado, et al. "Abstract 2522: Pathway and immune profile analysis of cyst-derived versus PanIN-derived pancreatic ductal adenocarcinomas." Cancer Research 82, no. 12_Supplement (2022): 2522. http://dx.doi.org/10.1158/1538-7445.am2022-2522.

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Abstract Introduction: Pancreatic cystic lesions (PCL) are common and a subset of mucinous cysts will transform into pancreatic ductal adenocarcinoma (PDAC). However, predicting which of these mucinous PCL may progress to PDAC and warrant surgery remains a clinical challenge. Moreover, identifying those clinically emergent mucinous PCL for which a surveillance approach is best is a dire clinical need. Therefore, we aimed to identify molecular signatures that distinguished between PDAC with and without clinical evidence of a PCL to identify novel biomarkers. Methods: We leveraged data from the

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Joseph, Witzard, Nancy Luckashenak, Kimberly Ramsey, James Clements, and Swami Padmanabhan. "The Adaptor Protein SLP-76 Is Not a Direct Substrate for BCR-ABL in the Chronic Myeloid Leukemia Cell Line K562." Blood 104, no. 11 (2004): 4699. http://dx.doi.org/10.1182/blood.v104.11.4699.4699.

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Abstract SLP-76(SH2 domain-containing leukocyte protein of 76 kD) is a hematopoietic adapter protein that is expressed in myeloid and T cells. SLP-76 is a substrate for tyrosine kinase in the src and syk family activation pathway required for T-cell receptor-mediated signaling. Cross-linking of the human FcgammaRIIa1 (CD32) in myeloid cells which contains an immune receptor tyrosine-based activation motif (ITAM) causes phosphorylation of SLP-76. Mice deficient in SLP76 develop fetal hemorrhage along with failure of T cell development and perinatal mortality. We have found that K562 cells expre

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Wang, Yuqing, Inae Park, Simo Du, Zhengrui Xiao, and Yizhou Chen. "Abstract 7424: Simplifying oncology terminology: Leveraging large language models for patient education." Cancer Research 85, no. 8_Supplement_1 (2025): 7424. https://doi.org/10.1158/1538-7445.am2025-7424.

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Abstract Introduction: Large language models (LLMs), such as OpenAI's ChatGPT-4, are designed to process natural language and generate responses to text-based prompts. While these models have shown promise in addressing clinical and patient-related inquiries, they are not specialized in medicine and lack integration with dedicated medical knowledge databases, leading to potential inaccuracies. On the other hand, healthcare professionals and models explicitly trained in medical texts frequently rely on specialized terminology, which can create significant barriers to clear and patient-friendly

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Dewar, David P. "Ethnographies and Exchanges: Native Americans, Moravians, and Catholics in Early North America, edited by A.G. RoeberEthnographies and Exchanges: Native Americans, Moravians, and Catholics in Early North America, edited by A.G. Roeber. Max Kade German-American Institute series. University Park, Pennsylvania State University Press, 2008. xxiv, 207 pp. $45.00 US (cloth)." Canadian Journal of History 43, no. 3 (2008): 565–67. http://dx.doi.org/10.3138/cjh.43.3.565.

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Ali, S., V. V. Rivera, and G. A. Secor. "First Report of Fusarium graminearum Causing Dry Rot of Potato in North Dakota." Plant Disease 89, no. 1 (2005): 105. http://dx.doi.org/10.1094/pd-89-0105b.

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Fusarium dry rot of potato can be caused by several species of Fusarium, but F. sambucinum is considered the primary cause in stored potatoes in North America and Europe (2). Potato tubers of cvs. Shepody and Russet Burbank with severe dry rot were collected from a commercial processing storage facility in central North Dakota during 2003–2004. Pathogen isolations were made from infected tubers on one-half strength acidified potato dextrose agar (APDA). Only F. graminearum was isolated from all rotted tubers used. Identification was based on colony morphology and conidial and perithecial chara

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Gupta, Anasuya Das, Natalia Krawczynska, Hashni Epa Vidana Gamage, et al. "Abstract 1258: 27-Hydroxycholesterol impairs lysosomal integrity in myeloid immune cells, resulting in enhanced secretion of cancer promoting extracellular vesicles." Cancer Research 83, no. 7_Supplement (2023): 1258. http://dx.doi.org/10.1158/1538-7445.am2023-1258.

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Abstract Background: Breast cancer is the most common cancer among women in the United States, with elevated circulating cholesterol as an established risk factor for the onset and progression to metastatic disease. The cholesterol metabolite, 27-hydroxycholesterol (27HC) has been identified to establish an immunosuppressive tumor microenvironment via Liver X Receptor (LXR) in myeloid immune cells. Interestingly, 27HC treatment of different myeloid immune cell types results in increased secretion of extracellular vesicles (EVs) with altered cargo. Importantly, EVs from 27HC treated myeloid cel

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Park, Juin, Woo Sun Kwon, Jingmin Che, et al. "Abstract 1399: Genomic profiling of gastric cancer with peritoneal metastasis identifies molecular subtypes and a potential molecular-guided therapeutic strategy for intractable gastric cancer." Cancer Research 83, no. 7_Supplement (2023): 1399. http://dx.doi.org/10.1158/1538-7445.am2023-1399.

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Abstract Patients with peritoneal metastasis frequently identified in advanced gastric cancer (GC) have a poor prognosis with a median survival of 3-6 months. Because of innate resistance to treatment, these patients have limited therapeutic efficacy and contribute to high mortality. Therefore, it is necessary to understand the molecular characteristics of peritoneal metastasis and search for applicable drugs. This study aims to understand the biological characteristics of peritoneal metastasis in GC through integrative genomic analysis.A total of 66 GC cell lines were used, of which 11 were d

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Davis, Andrew A., Ecaterina E. Dumbrava, Aparna Kalyan, et al. "Abstract CT159: Phase I trial of trastuzumab deruxtecan in combination with neratinib in solid tumors with HER2 alterations (NCI 10495)." Cancer Research 84, no. 7_Supplement (2024): CT159. http://dx.doi.org/10.1158/1538-7445.am2024-ct159.

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Abstract Background: Human epidermal growth factor receptor 2 (HER2) overexpression, amplification, or mutation occurs across a variety of solid tumors. Trastuzumab deruxtecan (T-DXd) is an antibody-drug conjugate (ADC) that has been approved by the FDA for HER2-overexpressed advanced breast, gastroesophageal cancers, HER2-low breast cancer, and HER2-mutated non-small cell lung cancer. However, some patients do not derive clinical benefit from T-DXd, and drug resistance is inevitable. Preclinical studies demonstrated that neratinib, an oral irreversible pan-HER tyrosine kinase inhibitor, can i

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Park, Su-Bin, Ji-Sik Kang, Min-Je Kim, Shin-Wha Lee, Dong-Woo Kang, and Yong-Man Kim. "Abstract 6190: Anti-tumor effects of lenvatinib plus anti-PD-1 in syngeneic murine cervical cancer models." Cancer Research 82, no. 12_Supplement (2022): 6190. http://dx.doi.org/10.1158/1538-7445.am2022-6190.

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Abstract Immune checkpoint inhibitors (ICIs) have been applied in patients with various solid tumors since they were approved by U.S. FDA in 2011. However, only less than 20% of patients benefit from ICIs including anti-programmed cell death protein 1 (aPD-1). Recently, many studies to improve the response of ICIs are in progress, and especially, vascular endothelial growth factor receptors (VEGFR) pathway was emerged as major target. VEGFR inhibitors regulate the differentiation of tumor-associated macrophage, antigen presenting dendritic cell, and T cell infiltration, so they make a synergic

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Mun, Han Byeol, juin Park, Jinsoo Jang, et al. "Abstract 229: Molecular-genomic characterization of metastatic gastric cancer organoids and establishment of organoid-immune cell co-culture model." Cancer Research 84, no. 6_Supplement (2024): 229. http://dx.doi.org/10.1158/1538-7445.am2024-229.

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Abstract Advanced gastric cancer (AGC) showed marked molecular heterogeneity with aggressive behavior and treatment resistance, especially AGC with ascites from peritoneal metastasis. Tumor organoids are valuable in vitro model for mimicking organ characteristics and are used for developing therapeutic strategies. Therefore, we aimed to understand the characteristics of organoids established from AGC patient-derived fluids. Also, we are in progress of setting up an organoid-immune cell co-culture model for drug screening of immune checkpoint inhibitors (ICI) for AGC. All established organoids

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Osterman, Carlos J. Diaz, Nicole Torres Muriel, Shannalee R. Martinez, et al. "Abstract A076: Evaluating cardiometabolic and oncologic risk among Puerto Rican men with prostate cancer." Cancer Research 83, no. 11_Supplement (2023): A076. http://dx.doi.org/10.1158/1538-7445.prca2023-a076.

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Abstract Background. Cardiovascular and metabolic disorders are significant contributors to mortality among men with prostate cancer. However, no evidence is yet available for the role of cardiometabolic comorbidities in the tumor risk stratification or clinical management of men with prostate cancer. Like African American men, Puerto Rican men have a higher risk of developing and dying from prostate cancer than other racial/ethnic groups in the United States. As cardiovascular and metabolic risk factors are highly prevalent in Puerto Rico, we proposed to investigate coordinated risk evaluatio

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Ammar, Usama, Mahmoud Gamal, Mohammed Abdel-Maksoud, et al. "Abstract 4472: Discovery of potential RAF-selective back pocket as a promising biological target for BRAF inhibitors in the treatment of resistant melanoma: Design, synthesis, biological evaluation and in silico studies." Cancer Research 84, no. 6_Supplement (2024): 4472. http://dx.doi.org/10.1158/1538-7445.am2024-4472.

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Abstract The mutated BRAF kinase (V600E) is considered the key component in the MAPK signaling pathway that was reported to be significantly contributed to melanoma disease. Vemurafenib and dabrafenib are examples of drugs that were approved by FDA to treat melanoma through inhibition of mutated BRAF kinase (V600E). However, drug resistance was reported after 6 - 7 months of treatment using these drugs due to activation of this signaling pathway through another RAF kinase (CRAF). As a Drug Discovery research group, we were interested to study and identify the possible biological target to inhi

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Park, Sook Ryun, Ming-Huang Chen, Arunee Dechaphunkul, et al. "Abstract CT274: BGB-A317-LBL-007-202: A phase 2, randomized, active-controlled, open-label study to evaluate the efficacy and safety of LBL-007 (anti-LAG-3) in combination with tislelizumab (TIS; anti-PD-1) plus chemotherapy (chemo) as first-line (1L) treatment in patients with unresectable locally advanced/metastatic esophageal squamous cell carcinoma (ESCC)." Cancer Research 84, no. 7_Supplement (2024): CT274. http://dx.doi.org/10.1158/1538-7445.am2024-ct274.

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Abstract Background: ESCC is the predominant histological subtype of esophageal cancer, accounting for 85% of cases. Patients (pts) with locally advanced/metastatic ESCC have poor clinical outcomes, with a 5-year survival rate of 6.1% for pts with distant metastases. 1L treatment with programmed cell death protein-1 (PD-1) inhibitors + platinum-based chemo has become the new standard of care for metastatic ESCC, however, there is an unmet need for enhanced treatment efficacy and a prolonged life span. LBL-007 is a monoclonal antibody (mAb) against lymphocyte activation gene-3 (LAG-3), an immun

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Marron, Thomas Urban, Nelson M. LaMarche, Matthew D. Park, et al. "Abstract CT199: Rescuing response to ICI by blocking the type-2 immune axis in patients with NSCLC progressing on immunotherapy: A phase 1b/2 trial of dupilumab administered with checkpoint blockade." Cancer Research 83, no. 8_Supplement (2023): CT199. http://dx.doi.org/10.1158/1538-7445.am2023-ct199.

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Abstract Type-2 cytokines are hypothesized to promote an immune-permissive milieu for cancer to grow. Through scRNAseq and CITEseq on human non-small cell lung cancer (NSCLC) and the krasG12Dp53−/− lung cancer model we previously described a tumor-enriched dendritic cell program of concomitant immunosuppression and activation which we termed the “mregDC,” that was also notable for a strong Th2 immune signature. We subsequently blocked the canonical Th2 cytokine IL-4 in vivo in tumor-bearing mice, and found that this significantly decreased lung tumor burden, which was recapitulated in multiple

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