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Articles de revues sur le sujet « American McAll Association »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 29 juillet 2025

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1

McGonigal, Kelly. "A Conversation with Timothy McCall, MD." International Journal of Yoga Therapy 19, no. 1 (2009): 143–47. http://dx.doi.org/10.17761/ijyt.19.1.q46072q4536g7652.

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Timothy McCall, MD, is a board-certified internist, the medical editor of Yoga Journal, and the author of two books, Yoga as Medicine: The Yogic Prescription for Health and Healing and Examining Your Doctor: A Patient's Guide to Avoiding Harmful Medical Care. His articles have appeared in dozens of publications, including the New England Journal of Medicine, Journal of the American Medical Association, The Nation, The Boston Globe, The Philadelphia Inquirer, and The Los Angeles Times. Timothy has studied Yoga since 1995 with Patricia Walden, a teacher of classical Iyengar Yoga. More recently,

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Alagesan, Priya, Paula Scotland, HannahSofia Brown, Shannon J. McCall, Meira Epplein, and Katherine S. Garman. "Abstract 5519: Biobanking of gastric organoid models from a racially diverse cohort for gastric cancer interception." Cancer Research 83, no. 7_Supplement (2023): 5519. http://dx.doi.org/10.1158/1538-7445.am2023-5519.

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Abstract Purpose: In the United States, significant disparities exist in gastric cancer incidence and mortality between Black Americans and non-Hispanic White Americans. Helicobacter pylori (HP) infection is the most important risk factor for developing non-cardia gastric adenocarcinoma (GAC), the most common type of gastric cancer. Non-cardia GAC is thought to occur via progression from HP-induced atrophic gastritis to gastric intestinal metaplasia (GIM), dysplasia, and cancer. The purpose of this study was to enroll racially diverse (~50% self-identified as Black) patients from the endoscopy

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McCall, Cordero L., James Stinson, Ryan W. Dobbs, et al. "Abstract A079: Genetic ancestry and vitamin D may predict degree of prostatic apoptosis in prostate tumor and benign epithelium among men undergoing radical prostatectomy." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): A079. http://dx.doi.org/10.1158/1538-7755.disp22-a079.

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Abstract There is evidence that vitamin D metabolites such as 25 hydroxyvitamin D [25(OH)D], may be protective against prostate cancer (PCa). Vitamin D and its analogs are hypothesized to have pro-apoptotic effects in multiple cell lines. Blacks have higher rates of vitamin D deficiency, higher tumor progression rates 1,2, and higher apoptosis rates3 compared to Whites. West African ancestry (WAA) may confound this relationship if it is associated with both vitamin D status and apoptosis rates. Our objective is to assess for independent associations between in vivo vitamin D status, genetic an

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Sedani, Ami E., Jessica Y. Islam, Derek M. Griffith, et al. "Abstract 796: Exploring the impact of masculine beliefs on colorectal cancer screening participation among Hispanic/Latino men in Florida, New York, and Texas." Cancer Research 84, no. 6_Supplement (2024): 796. http://dx.doi.org/10.1158/1538-7445.am2024-796.

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Abstract Introduction: The existing literature on colorectal cancer-related inequities among Hispanic/Latino men may be poorly descried as most outcome data to date for this ethnic group are reported in aggregate. This study explored how masculine beliefs may influence colorectal cancer screening participation among ethnic subgroups of Hispanic/Latino men aged 45-75 years. Methods: Utilizing a consumer panel, self-identified Hispanic/Latino men that were age-eligible for colorectal cancer screening and fluent in either English or Spanish were recruited from Florida, New York, and Texas (Februa

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Solit, David B., Niharika B. Mettu, Shannon J. McCall, et al. "Abstract 930: Treatment patterns and overall survival among men with metastatic castration-resistant prostate cancer harboring DDR mutations." Cancer Research 83, no. 7_Supplement (2023): 930. http://dx.doi.org/10.1158/1538-7445.am2023-930.

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Abstract Background: Limited information is available about treatments and clinical outcomes among men with metastatic castration-resistant prostate cancer (mCRPC) whose tumors harbor DNA damage repair (DDR) mutations. Methods: This retrospective chart review study included men diagnosed with mCRPC with ≥1 DDR mutation detected by tumor comprehensive genomic profiling who began a line of therapy on or after July 1, 2014, at oncology centers in the American Association for Cancer Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) consortium. The index date was the

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Gordon, Vinessa, Folakemi Odedina, Kimling Tam Ashing, et al. "Abstract 818: Fighting prostate cancer with a multimedia approach." Cancer Research 84, no. 6_Supplement (2024): 818. http://dx.doi.org/10.1158/1538-7445.am2024-818.

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Abstract Introduction: Black men have the highest prostate cancer (CaP) mortality rates. The reason for this disparity is multifaceted, including the barriers that they face at the individual, provider, and health system levels. To address these challenges the iCCaRE for Black Men Consortium uses a multi-level approach to disseminating CaP information. This approach is rooted in research which shows that Black men prefer to receive information through multi-media channels tailored to their needs. In addition, studies have reported that CaP survivors were viewed as credible sources of informati

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Leatham, Bryan, Katie McNall, Hari K. Subramanian, et al. "Abstract 2929: High-Definition Digital PCR (HDPCR™) enables sensitive measurement of DNA and RNA variants in non-small cell lung cancer samples." Cancer Research 82, no. 12_Supplement (2022): 2929. http://dx.doi.org/10.1158/1538-7445.am2022-2929.

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Abstract Digital PCR (dPCR) is an emerging platform for detecting genomic variants in cancer genomes due to its high sensitivity and fast time to result compared to massively parallel sequencing. However, translational oncology applications often require the measurement of more biomarkers than there are color channels available on dPCR platforms. One approach to address this is to split a sample across many wells and profile a subset of variants in each well. For input-limited samples, however, this results in fewer molecules being profiled in each well, resulting in a reduction in sensitivity

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Truong, Danh, David McCall, Clement Agyemang, Sandhya Krishnan, Alexander Lazar, and Joseph Ludwig. "Abstract 129: Understanding the molecular drivers that regulate Ewing sarcoma cell fate." Cancer Research 84, no. 6_Supplement (2024): 129. http://dx.doi.org/10.1158/1538-7445.am2024-129.

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Abstract Like other translocation-positive sarcomas, Ewing sarcoma (ES) harbors a pathognomonic fusion protein (FP) capable of widespread epigenetic reprogramming that can lead cells to acquire a high-grade, undifferentiated phenotypic state. To better understand how this might occur, we employed a CRISPR knockout (CRISPR-KO) model of A673, targeting exon 4 of the N-terminus EWSR1 portion of the FP and generated a clonal pool (EWSR1 CRISPR KO). We used single-cell RNA and ATAC sequencing (scMultiome) to identify the transcriptional and chromatin changes after the FP knockout (FP KO). We identi

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Kaninjing, Ernest, Gladys Asiedu, Kaitlin Van Voorhis, et al. "Abstract 1310: Social determinants of migrant health factors impacting prostate cancer care and survivorship among sub-Saharan African immigrant men diagnosed with prostate cancer." Cancer Research 84, no. 6_Supplement (2024): 1310. http://dx.doi.org/10.1158/1538-7445.am2024-1310.

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Abstract Background: Sub-Saharan African Immigrants (SSAI) represent one of the fastest-growing segments of the immigrant population in the United States (US). Between 2010 and 2018, the SSAI population in the US increased by 53%, significantly outpacing the 12% growth rate for the overall foreign-born population in the US during that time frame. Despite these growing numbers, little is published about the extent to which SSAIs adapt to health behaviors more common in the US or remain immersed in the values, beliefs and practices reflective of their country of origin. Importantly, no study has

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Ashing, Kimlin Tam, Timethia Bonner, Ewan K. Cobran, et al. "Abstract 994: Advancing health equity and reducing disparities in prostate cancer in Black men: iCCaRE." Cancer Research 85, no. 8_Supplement_1 (2025): 994. https://doi.org/10.1158/1538-7445.am2025-994.

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Abstract In the US and globally, Black men experience the highest prostate cancer burden among all racial and ethnic groups, underscoring the urgent need for research to guide the development and implementation of culturally tailored strategies aimed at reducing disparities and improving outcomes. In response, the Inclusive Cancer Care Research Equity (iCCaRE) Consortium was created to advance health equity and reduce disparities in prostate cancer. Importantly, a Survivorship Care Plan (SCP) is recommended to educate and empower patients, enabling them to be better informed about their cancer

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Graves, Laurie, Gabrielle Rupprecht, Erdem Altunel, et al. "Abstract 1061: Exportin 1 (XPO1) inhibition alone or in combination as a novel therapeutic strategy in osteosarcoma." Cancer Research 82, no. 12_Supplement (2022): 1061. http://dx.doi.org/10.1158/1538-7445.am2022-1061.

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Abstract Background: Osteosarcoma is an aggressive bone cancer in which therapeutic advancements have been limited over the last 30 years, in part due to genomic heterogeneity. The combination of high-throughput drug screening platforms that efficiently pinpoint drug sensitivities with patient-derived cross-species models is an innovative approach to address the critical need to identify novel treatment strategies for osteosarcoma patients. Methods: We performed high-throughput drug screens on patient-derived osteosarcoma cell lines D418 (canine) and 17-3x (human), followed by validation of th

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Boyer, Michael, Michelle Townsend, Timothy Phares, et al. "Abstract 5250: Chimeric antigen receptor macrophages (MOTO CARs) driving repolarization of macrophages in solid tumors." Cancer Research 84, no. 6_Supplement (2024): 5250. http://dx.doi.org/10.1158/1538-7445.am2024-5250.

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Abstract Introduction: Though chimeric antigen receptor (CAR) T cells have been effective in treating hematological cancers, they have lacked in solid tumors. Due to the nature of solid tumors and how macrophages are localized there, we propose that macrophages are a better cell type for targeting solid tumors. In tumors, most of the macrophages are Tumor Associated Macrophages (TAMs) which are M2 polarized and promote tumor growth, angiogenesis, and metastases. If these macrophages could be repolarized to an anti-tumor, M1 phenotype, they could alter the tumor immune microenvironment and faci

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Sedani, Ami E., Kelly K. Rifelj, Malcolm S. Bevel, et al. "Abstract 3469: Exploring the impact of a giant inflatable colon on the level of awareness, knowledge, and intent for colorectal cancer screening among men attending two state fairs in the Midwest." Cancer Research 84, no. 6_Supplement (2024): 3469. http://dx.doi.org/10.1158/1538-7445.am2024-3469.

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Abstract Purpose: This study aimed to evaluate the influence of an interactive inflatable colon as an effective educational tool to increase colorectal cancer (CRC) awareness, knowledge, and screening intention among men attending the Wisconsin (WI) and Minnesota (MN) state fairs. Methods: Eligible study participants were self-identified men aged 18-75 who spoke English, were residents of WI or MN, and able to read in English. The study was employed during the final operating weekend of both the 2023 WI State Fair (August 11-13) and the MN State Fair (September 1-3). Eligible participants comp

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Morrison, James C., Kimlin T. Ashing, Gaole Song, et al. "Abstract 808: iCCaRE engagement of faith-based organizations to co-create and co-disseminate infographics addressing disparities in prostate cancer literacy and clinical and biospecimen studies." Cancer Research 84, no. 6_Supplement (2024): 808. http://dx.doi.org/10.1158/1538-7445.am2024-808.

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Abstract Black men hold the highest prostate cancer burden among all ethnicities; thus, there is an urgent need for research to inform the development and implementation of a culturally tailored intervention to reduce disparities and improve outcomes. In response, the Inclusive Cancer Care Research Equity (iCCaRE) Consortium was created to advance health equity and reduce disparities in prostate cancer. Addressing the unique needs of Black men require a genuine bidirectional relationship between scientist and the community. In the Black community, faith-based organizations are respected instit

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Liu, Yueying, Pankaj K. Singh, Lyndsay E. Young, et al. "Abstract 4164: Targeting glycogen metabolism as a potential therapy for Ewing sarcoma." Cancer Research 85, no. 8_Supplement_1 (2025): 4164. https://doi.org/10.1158/1538-7445.am2025-4164.

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Abstract Ewing sarcoma (EWS) is a malignant bone tumor or soft-tissue tumor that mainly affects children, adolescents, and young adults. We recently demonstrated that the PAS+ accumulations in EWS indicate extensive deposits of glycogen, a macro-metabolite that provides an immediate source of glucose to support cellular energy needs. In this study, we sought to elucidate the role of glycogen and its related enzymes in EWS tumorigenesis and metastasis. Though complex carbohydrates like glycogen are traditionally difficult to study due to their biochemical and biophysical properties, the Gentry

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Truong, Danh, Sandhya Krishnan, Alexandar Lazar, David McCall, and Joseph A. Ludwig. "Abstract 3559: Understanding Ewing sarcoma cell fate." Cancer Research 83, no. 7_Supplement (2023): 3559. http://dx.doi.org/10.1158/1538-7445.am2023-3559.

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Abstract Like several other translocation-positive sarcomas, Ewing sarcoma (ES) exists exclusively in a high-grade, undifferentiated state. We believe that the pathognomonic EWS-FLI1 fusion protein (FP) responsible for ES is intimately linked to cell fate, differentiation, and plasticity. Over the last two decades, an emerging body of research has begun the challenging task of deciphering how the FP - via its action as an aberrant transcription factor- blocks differentiation and promotes reprogramming toward a quasi-stem-like cell with features of neuroectodermal or mesenchymal stem cells. We

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Aitken, Charlotte Kate, Katie Bushby, Petra Hamerlik, et al. "Abstract 1879: A novel therapeutics accelerator for the brain cancer community: Early lessons learned." Cancer Research 84, no. 6_Supplement (2024): 1879. http://dx.doi.org/10.1158/1538-7445.am2024-1879.

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Abstract Developing a comprehensive translational program for brain tumors is a complex task that involves numerous challenges. These challenges include significant obstacles surrounding the delivery of pre-clinical studies, safety, clinical trial design, and routes to commercialization. Recognizing that this journey is difficult, in 2023 the Tessa Jowell Brain Cancer Mission launched the Brain Tumor Research Novel Therapeutics Accelerator (BTR-NTA). The BTR-NTA is a new international accelerator program that provides independent and comprehensive expert guidance to de-risk therapeutic develop

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Bobbili, Priyanka, Jasmina Ivanova, David B. Solit, et al. "Abstract P4-01-30: Real-world treatment patterns and survival among adults with metastatic breast cancer with BRCA1/2 mutations." Cancer Research 83, no. 5_Supplement (2023): P4–01–30—P4–01–30. http://dx.doi.org/10.1158/1538-7445.sabcs22-p4-01-30.

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Abstract Background: Limited information is available about real-world treatment patterns and survival among patients with metastatic breast cancer (mBC) with BRCA1/2 mutations. BRCA1/2 mutations, which are involved in the repair of DNA double-strand breaks, are rare. Since 2018, PARP inhibitors (olaparib and talazoparib) have been approved for the treatment of patients with germline BRCA-mutated HER2-negative locally advanced and/or mBC. Methods: This retrospective chart review study included adults diagnosed with mBC with ≥1 oncogenic somatic BRCA1/2 mutation detected by tumor comprehensive

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Biljana, Kapusevska, Dereban Nikola, Bundevska Jadranka, Stavrova Natasha, Sahpaska BudimaPejkovska, and DMD MarijaAndonovska. "Dental Methods in the Medical Treatment of Tension Headache." Biolife 6, no. 1 (2022): 51–55. https://doi.org/10.5281/zenodo.7398561.

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<strong>ABSTRACT</strong> The tension headache is a common recurring affliction in the population with prevalence of 12%. Purpose is to vindicate the medico-dental approach in treatment of tension headache. Each of the 120patients for this study underwent a screening process for the patognostic symptoms that lead to diagnosing tension headache: strong temporal pulsating pain, nausea, photophobia, phonophobia, parastesia and/or light flashing hallucinations. The patients were divided into 2separate groups. The 1group of 60patients were treated with pharmaceuticals almotriptan 15mg/day and ibupr

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Koebnick, Corinna, Mary Helen Black, Jun Wu, Yu-Hsiang Shu, Thomas Buchanan, and Anny Xiang. "Abstract MP013: Diet High in Sweets and Sugar-sweetened Beverages But Low in Fruits and Vegetables is Associated With Pro-inflammatory Adipokine Profile in Mexican Americans at Risk For Diabetes." Circulation 135, suppl_1 (2017). http://dx.doi.org/10.1161/circ.135.suppl_1.mp013.

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Background: High consumption of sweets and sugar-sweetened beverages is associated with obesity, insulin resistance and cardiovascular disease. Pro- and anti-inflammatory adipokines may mediate the relationship between dietary intake and poor metabolic profile. However, studies investigating the association between diet and adipokines are scant and often restricted to one or two biomarkers. Study design and methods: Subjects were participants of BetaGene, a study of obesity, insulin resistance and β-cell dysfunction in Mexican Americans (n=1,128, 73% female, age 34.6±8.0, BMI 29.5±5.9). Adipon

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