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Articles de revues sur le sujet « And Atopic Dermatitis Natural therapy »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

Mavlyanova, Sh Z., A. I. Ismоgilov, and Sh N. Mirzakulova. "Detoxifying therapeutic effect of the natural mineral glauconite in patients with atopic dermatitis." Terapevt (General Physician), no. 4 (April 6, 2023): 24–32. http://dx.doi.org/10.33920/med-12-2304-03.

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The article presents the results of clinical and laboratory studies of a new way of detoxifying the body with the external use of natural activated Uzbekistan glauconite ("Fatigrin") in patients with atopic dermatitis. Clinical, biochemical, and microbiological research methods have shown that in patients with atopic dermatitis, endogenous intoxication is accompanied by a disorder in the syndrome of colonization resistance of opportunistic microorganisms with a shift in skin pH to an alkaline environment, depending on the severity of the disease. The use of pelotherapy with glauconite mineral

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Nurleni, Nurleni, and Novita Novita. "Perbedaan Efektifitas Antara Minyak Kelapa dan Lidah Buaya Terhadap Penyakit Dermatitis Atopik pada Balita di Kecamatan Cikeusal." Malahayati Nursing Journal 5, no. 10 (2023): 3403–15. http://dx.doi.org/10.33024/mnj.v5i10.9385.

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ABSTRACT WHO states that 5‒20% of children have atopic dermatitis, Serang Regency itself has around 65.4%. One of the topical therapy for atopic dermatitis is by using a moisturizer. Coconut oil and aloe vera can be used as natural moisturizers. Cikeusal District, Serang Banten Regency, on average, around 30-31 children under five experience atopic dermatitis every month. Knowing the difference in effectiveness between coconut oil and aloe vera against atopic dermatitis in toddlers in Cikeusal District in 2022. This research is a quasy experimental design with a pretest-post test with control

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Suk, Seo Kyoung, and Chang-Gue Son. "Beneficial Effects of Natural Environment Therapy for Atopic Dermatitis." Journal of Korean Medicine 38, no. 2 (2017): 1–6. http://dx.doi.org/10.13048/jkm.17012.

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Silva, Giuliane do Nascimento, Luís Felipe da Costa Zulim, Sarah Ferraz Simoes Martinez, and Carolina Bresqui Durante. "ATOPIC DERMATITIS IN A MALE SHIH TZUDOG." COLLOQUIUM AGRARIAE 20, no. 1 (2024): 1–7. http://dx.doi.org/10.5747/ca.2024.v20.h531.

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Atopic dermatitis in dogs is a chronic skin condition caused by allergies to environmental allergens such as pollen and dust mites. Symptoms include itching, inflammation and skin lesions. Diagnosis is based on clinical symptoms and exclusion of other diseases. Treatment includes environmental control measures, drug baths, immunomodulatory therapy and use of anti-inflammatory drugs. Prevention is done through appropriate environmental and food management. In this article, a case of atopic dermatitis will be reported in a male Shih Tzu dog treated at the Veterinary Hospital of the University of

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Mochulska, O. M., T. V. Hariyan, I. M. Horishnyi, and N. M. Yarema. "Using of emollients in children with atopic dermatitis (literature review)." Modern pediatrics. Ukraine, no. 1(129) (February 27, 2023): 65–71. http://dx.doi.org/10.15574/sp.2023.129.65.

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Modern external pharmacotherapy of atopic dermatitis in children should be etiopathogenetic and effects on the mechanisms of formation of allergic inflammation. External therapy of atopic dermatitis in children consists in the local application of emollients, glucocorticosteroids, antileukotriene, antihistamine medications, topical calcineurin inhibitors, in the case of complicated forms - antibacterial, antifungal, antiviral medications along with skin care. Eliminating dryness of the skin is the most important part of the external therapy of atopic dermatitis. Emollients are the main agents

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B. Gunt, Hemali. "Natural Skin Care Regimen Improves Clinical Parameters and Quality of Life in Children with Atopic Dermatitis." Dermatology and Dermatitis 9, no. 6 (2024): 01–06. http://dx.doi.org/10.31579/2578-8949/171.

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Background: Atopic dermatitis (AD) is a prevalent, chronic inflammatory skin disorder, characterized by xerosis, itching and recurrent eczematous lesions. The condition also has major psychosocial implications for patients and their families. A daily skincare regimen of gentle cleansing and moisturization is an important part of atopic dermatitis therapy. Objective: This study evaluated the tolerability and efficacy of a nature-based shampoo/wash and moisturizer in children with mild to moderate atopic dermatitis Methods: This open-label study involved 23 children (6 months – 13 years) with at

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Popiel, Jarosław, Agnieszka Cekiera, Agnieszka Kurosad, Urszula Pasławska, Agnieszka Noszczyk-Nowak, and Józef Nicpo. "Antipruritic application of ovocystatin in atopic dermatitis in dogs - preliminary study." Bulletin of the Veterinary Institute in Pulawy 58, no. 4 (2014): 639–43. http://dx.doi.org/10.2478/bvip-2014-0097.

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Abstract The study was an attempt to determine the possibilities of using ovocystatin, a component of a new generation product of natural origin, in local therapy of atopic dermatitis in dogs by suppressing pruritus during illness. Chicken egg cystatin was used locally in the interdigital spaces of forelimbs of dogs used in the experiment. The degree of pruritus and clinical changes in the animals were defined using CADESI-03 scale before and after the beginning of the experiment. The results obtained proved that ovocystatin may be used as a substance suppressing pruritus in atopic dermatitis.

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Goncharova, O. V., O. A. Komissarova, D. B. Kameldenova, et al. "Skin care in children with atopic dermatitis." Voprosy praktičeskoj pediatrii 16, no. 3 (2021): 134–40. http://dx.doi.org/10.20953/1817-7646-2021-3-134-140.

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In this article, we described specific features of baby skin and care for it (washing baby's face, bottom; cleaning ears, nose, and eyes; baby's bathing). We also assessed the efficacy of cream-balm ‘Tamba-PS’ (‘Adonis’ LLC, Russia) for the treatment of atopic dermatitis. ‘Tamba-PS’ contains only natural ingredients, including oil extract of native peloids from Lake Tambukan, plant extracts and essential oils, propolis, mumiyo, beeswax, honey, olive oil, sea buckthorn oil, coconut oil, and lecithin. We demonstrated its efficacy in infants and children aged 3 months to 3 years with both focal s

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Мavlyanova, Sh Z., A. I. Ismogilov, J. B. Mullakhanov, A. U. Burkhanov, and Sh Khonkhodjaev. "New possibilities of external therapy for atopic dermatitis based on the use of natural silicon oxide." Terapevt (General Physician), no. 10 (October 15, 2020): 44–51. http://dx.doi.org/10.33920/med-12-2010-04.

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The article presents new approaches to the external therapy of atopic dermatitis using a moisturizing, toning, anti-inflammatory cream «Fatiderm». Clinical studies have shown that Fatiderm cream helps to reduce the severity of the dermatological index of the symptom scale, eliminate subjective sensations, and improve the dynamics of the skin pathological process.

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Wardoyo, Aryananda Haris, Andrew Soerijadi, and Linda Julianti Wijayadi. "Peran Helichrysum italicum sebagai Anti Inflamasi pada Terapi Dermatitis Atopi." Cermin Dunia Kedokteran 49, no. 12 (2022): 708–10. http://dx.doi.org/10.55175/cdk.v49i12.331.

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Dermatitis atopik (DA) merupakan salah satu penyakit inflamasi kulit kronis yang terjadi dengan karakteristik kulit kering, berskuama, dan eritema. Pengobatan DA selain terapi konvensional atau penggunaan biologic agent, diteliti juga pengobatan alternatif menggunakan bahan alami; di antaranya Helichrysum italicum. Manfaat H. italicum adalah sebagai anti-mikroba, anti-inflamasi, anti-viral, anti-oksidan, dan anti-larvisidal. Sudah ada aplikasi H. italicum sebagai terapi tambahan dan alternatif penderita DA.  Atopic dermatitis (AD) is a chronic inflammatory skin disease that occurs

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Mack, Madison R., Jonathan R. Brestoff, Melissa M. Berrien-Elliott, et al. "Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis." Science Translational Medicine 12, no. 532 (2020): eaay1005. http://dx.doi.org/10.1126/scitranslmed.aay1005.

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Atopic dermatitis (AD) is a widespread, chronic skin disease associated with aberrant allergic inflammation. Current treatments involve either broad or targeted immunosuppression strategies. However, enhancing the immune system to control disease remains untested. We demonstrate that patients with AD harbor a blood natural killer (NK) cell deficiency that both has diagnostic value and improves with therapy. Multidimensional protein and RNA profiling revealed subset-level changes associated with enhanced NK cell death. Murine NK cell deficiency was associated with enhanced type 2 inflammation i

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Idée, Adrien, Marion Mosca, and Didier Pin. "Skin Barrier Reinforcement Effect Assessment of a Spot-on Based on Natural Ingredients in a Dog Model of Tape Stripping." Veterinary Sciences 9, no. 8 (2022): 390. http://dx.doi.org/10.3390/vetsci9080390.

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Skin barrier restoration is an important part of atopic dermatitis therapy. We investigated the effect of a spot-on containing plant-based essential fatty acids and essential oils on skin barrier parameters in a dog model of acute skin barrier disruption, using five healthy beagle dogs maintained in a laboratory setting. Four test sites on the dorsum and a control site on the abdomen were defined on each dog. Transepidermal water loss (TEWL) and skin surface hydration (SSH) were measured before and after tape stripping on the first day and then for three consecutive days, over four consecutive

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Warowna, Marlena, Agnieszka Sobolewska-Samorek, Małgorzata Gorzel, and Edyta Kwilosz. "Thalassotherapy as a multidirectional form of marine resources therapy." Fizjoterapia Polska 23, no. 5 (2023): 176–84. http://dx.doi.org/10.56984/8zg20bt5i.

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Thalassotherapy is a treatment that uses the natural gifts of the sea (climate, air, sea sand, algae, some species of sea fish, mother of pearl) and physical factors (hydrotherapy, heliotherapy, aerosol therapy, music therapy, kinesitherapy and others). It is mainly intended for people who are stressed, overtired and have sleep problems. Thalassotherapy is also used in the treatment of rheumatism, back pain, lung diseases, heart diseases and skin dermatoses, such as psoriasis or atopic dermatitis. These treatments are widely used in wellness centers as care and therapeutic treatments for probl

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Di Salvo, Eleonora, Sebastiano Gangemi, Claudia Genovese, Nicola Cicero, and Marco Casciaro. "Polyphenols from Mediterranean Plants: Biological Activities for Skin Photoprotection in Atopic Dermatitis, Psoriasis, and Chronic Urticaria." Plants 12, no. 20 (2023): 3579. http://dx.doi.org/10.3390/plants12203579.

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Polyphenols are a diverse class of natural compounds that are widely distributed in various fruits, vegetables, and herbs. They possess antioxidant and anti-inflammatory properties and bring benefits in the prevention and treatment of various diseases. Studies suggested that polyphenols may improve cardiovascular health and may have neuroprotective effects. The Mediterranean region is a vast area. Although the territory encompasses a wide variety of cultures and dietary patterns, there are some commonalities in terms of the plant-based foods and their polyphenol content. Such polyphenols have

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Helga Pasadena and Santi Widiasari. "Efektivitas Curcumin Dalam Mengurangi Peradangan Pada Dermatitis Atopik." Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran 3, no. 2 (2025): 47–53. https://doi.org/10.55606/termometer.v3i2.4881.

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Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritus, erythema, and impaired skin barrier function. Conventional treatments such as topical corticosteroids and calcineurin inhibitors effectively reduce inflammation but pose potential adverse effects that limit their long-term use. Consequently, natural-based alternatives like curcumin have gained increasing interest. Curcumin, a principal polyphenol in turmeric (Curcuma longa), is known for its anti-inflammatory, antioxidant, and immunomodulatory properties. Its mechanisms in AD involve the inhibition of the

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Chien, Chih-Hao, and Kue-Hsiung Hsieh. "Interleukin-2 Immunotherapy in Children." Pediatrics 86, no. 6 (1990): 937–43. http://dx.doi.org/10.1542/peds.86.6.937.

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Immunotherapy with interleukin (IL)-2 possesses great potential in the treatment of immdiatedne-mediated diseases and cancers. However, only a few reports on a small number of children have appeared in the literature. From March 1988 to March 1989, 11 children and adolescents were treated with IL-2. They included 1 patient with hepatocellular carcinoma, 1 with hepatoblastoma, 6 with childhood atopic dermatitis, and 3 with juvenile rheumatoid arthritis. The dosages ranged from 10 000 to 50 000 U/kg every 8 hours by intravenous drip. The following side effects were observed: anorexia, fever, and

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Boudková, Petra, Jarmila Čelakovská, Eva Čermáková, Ctirad Andrýs, and Jan Krejsek. "Immunological Parameters in Patients Suffering from Atopic Dermatitis and Either Treated or Non-Treated with Dupilumab." Acta Medica (Hradec Kralove, Czech Republic) 66, no. 2 (2023): 47–54. http://dx.doi.org/10.14712/18059694.2023.15.

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Objective: The aim of the study is to analyze the absolute count of leukocytes, neutrophils, monocytes, eosinophils, T cells, natural killer cells, B cells and to evaluate the expression of functionally important CD23 and CD200 molecules on B cells in patients suffering from atopic dermatitis (AD), (with and without dupilumab therapy). Materials and Methods: We examined 45 patients suffering from AD – 32 patients without dupilumab treatment (10 men, 22 women, average age 35.0 years), 13 patients with dupilumab treatment (7 men, 6 women, average age 43.4 years) and 30 healthy control (10 men, 2

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Yon, Jessica-Ai-Lyn, Sue-Kei Lee, Jing-Wen Keng, et al. "Cassia alata (Linnaeus) Roxburgh for Skin: Natural Remedies for Atopic Dermatitis in Asia and Their Pharmacological Activities." Cosmetics 10, no. 1 (2022): 5. http://dx.doi.org/10.3390/cosmetics10010005.

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Atopic dermatitis (AD) is an inflamed skin condition with relapsing pruritus and cutaneous physiological dysfunction. This skin disorder is widespread around the world and frequently affects infants, children and adults. Natural products with bioactive lead compounds are the source of natural medicines for complementary and alternative therapy in managing AD. Cassia alata has been used traditionally as a remedy for a variety of health issues. In Asian countries, it is used as an ethnomedicine to treat skin conditions such pityriasis versicolor, ringworm, scabies, shingles, urticaria and itchin

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Sitarek, Przemysław, Tomasz Kowalczyk, Joanna Wieczfinska, et al. "Plant Extracts as a Natural Source of Bioactive Compounds and Potential Remedy for the Treatment of Certain Skin Diseases." Current Pharmaceutical Design 26, no. 24 (2020): 2859–75. http://dx.doi.org/10.2174/1381612826666200417160049.

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Skin ailments present a major health burden in both developed and undeveloped countries. Maintaining healthy skin is important for a healthy body. Medicinal plants have long provided reliable therapy in the treatment of skin diseases in humans through a diverse range of bioactive molecules. Skin diseases may have a various basis, or may be genetically determined; together, they constitute approximately 34% of all occupational diseases encountered in people of all ages. Of these, melanoma is one of the most dangerous forms, with very poor prognosis for patients if it is diagnosed too late. This

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Camargo, Guilherme dos Anjos, Leandro Ferreira, Diego José Schebelski та ін. "Characterization and In Vitro and In Vivo Evaluation of Tacrolimus-Loaded Poly(ε-Caprolactone) Nanocapsules for the Management of Atopic Dermatitis". Pharmaceutics 13, № 12 (2021): 2013. http://dx.doi.org/10.3390/pharmaceutics13122013.

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Background: Tacrolimus (TAC) is a drug of natural origin used in conventional topical dosage forms to control atopic dermatitis. However, direct application of the drug often causes adverse side effects in some patients. Hence, drug nanoencapsulation could be used as an improved novel therapy to mitigate the adverse effects and enhance bioavailability of the drug. Methods: Physicochemical properties, in vitro drug release experiments, and in vivo anti-inflammatory activity studies were performed. Results: TAC-loaded nanocapsules were successfully prepared by the interfacial deposition of prefo

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Gębka-Adamczyk, Natalia, Joanna Głogowska-Szeląg, Jakub Adamczyk, and Marta Szeląg. "Balneotherapy and thermal resort in dermatology." Acta Balneologica 66, no. 3 (2024): 198–201. http://dx.doi.org/10.36740/abal202403108.

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One of the oldest specialties in medicine is balneotherapy, which examines how to treat patients with mud and groundwater. Many nations use water therapy as a kind of treatment. The Blue Lagoon in Iceland, the Dead Sea in Israel, the Kangal hot springs in Turkey, several thermal pools in France, as well as Poland, are examples of natural balneotherapy locations. For the patient, this therapy is painless, and there are almost no adverse effects. Its positive effects have also been demonstrated in the management of lupus, psoriasis, atopic dermatitis, rosacea and other inflammatory skin conditio

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CHATTERJEE, Sudipta, and Patrick Chi-leung HUI. "Review of Stimuli-Responsive Polymers in Drug Delivery and Textile Application." Molecules 24, no. 14 (2019): 2547. http://dx.doi.org/10.3390/molecules24142547.

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This review describes some commercially available stimuli-responsive polymers of natural and synthetic origin, and their applications in drug delivery and textiles. The polymers of natural origin such as chitosan, cellulose, albumin, and gelatin are found to show both thermo-responsive and pH-responsive properties and these features of the biopolymers impart sensitivity to act differently under different temperatures and pH conditions. The stimuli-responsive characters of these natural polymers have been discussed in the review, and their respective applications in drug delivery and textile es

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Lei, Xuan, Sabine Ring, Shiying Jin, Sonali Singh, and Karsten Mahnke. "Extracellular Vesicles and Their Role in Skin Inflammatory Diseases: From Pathogenesis to Therapy." International Journal of Molecular Sciences 26, no. 8 (2025): 3827. https://doi.org/10.3390/ijms26083827.

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Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are released into the extracellular space by almost all known cell types. They facilitate communication between cells by transferring bioactive molecules, which impact both physiological processes and the development of diseases. EVs play a crucial role in the pathogenesis of various diseases by participating in multiple pathological processes. They contribute to disease progression by triggering cytokine release, modulating immune cell activity, and inducing inflammatory and immune responses. Beyond their p

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Abuabara, Katrina, Jonathan I. Silverberg, Eric L. Simpson, et al. "International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale." BMJ Open 10, no. 11 (2020): e039928. http://dx.doi.org/10.1136/bmjopen-2020-039928.

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IntroductionAs new topical and systemic treatments become available for atopic dermatitis (AD), there is a need to understand how treatments are being used in routine clinical practice, their comparative effectiveness and their long-term safety in diverse clinical settings.Methods and analysisThe TARGET-DERM AD cohort is a longitudinal, observational study of patients with AD of all ages, designed to provide practical information on long-term effectiveness and safety unobtainable in traditional registration trials. Patients with physician-diagnosed AD receiving prescription treatment (topical

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Błońska-Sikora, Ewelina Maria, Marta Klimek-Szczykutowicz, Monika Michalak, Katarzyna Kulik-Siarek, and Małgorzata Wrzosek. "Potential Possibilities of Using Peat, Humic Substances, and Sulfurous Waters in Cosmetology." Applied Sciences 14, no. 16 (2024): 6912. http://dx.doi.org/10.3390/app14166912.

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Balneology is one of the oldest fields of medicine related to the use of natural raw materials (medicinal waters, medicinal gases, peloids, climatic values) in the treatment, prevention, and rehabilitation of many diseases but also increasingly in cosmetology. Currently, balneotherapy (spa therapy) combines tradition and modernity. The interest in spa treatments, the popularity of a healthy lifestyle, as well as the constant search for active substances of a natural origin for cosmetics make peloids, medicinal, and mineral waters very popular in the cosmetics industry. The main aim of this rev

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Al-Waili, Noori S. "Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study." Complementary Therapies in Medicine 11, no. 4 (2003): 226–34. http://dx.doi.org/10.1016/s0965-2299(03)00120-1.

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Ahmad, Javed. "Lipid Nanoparticles Based Cosmetics with Potential Application in Alleviating Skin Disorders." Cosmetics 8, no. 3 (2021): 84. http://dx.doi.org/10.3390/cosmetics8030084.

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The lipids mainly oils, fats, waxes and phospholipids are of substantial importance in the development and functioning of cosmetic products. The lipid nanoparticles-based cosmetic product is highly capable of protecting the skin against harmful radiations and is utilized for anti-aging therapy. Naturally derived antioxidants such as carotenoids, retinoids and tocopherols could be employed for their antioxidant properties as therapeutics and skincare active moieties in cosmetic products. Such a lipid nanoparticles-based cosmetic formulation consisting of antioxidants are very effective against

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Alessandrello, Clara, Serena Sanfilippo, Paola L. Minciullo, and Sebastiano Gangemi. "An Overview on Atopic Dermatitis, Oxidative Stress, and Psychological Stress: Possible Role of Nutraceuticals as an Additional Therapeutic Strategy." International Journal of Molecular Sciences 25, no. 9 (2024): 5020. http://dx.doi.org/10.3390/ijms25095020.

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Atopic dermatitis (AD) is a chronic inflammatory skin condition with a considerable impact on patients’ quality of life. Its etiology is multifactorial and, among the predisposing factors, a role is played by oxidative stress. Pollution, recurrent infections, and psychological stress contribute to oxidative stress, amplifying the production of proinflammatory cytokines and worsening barrier damage. There are various oxidative stress mechanisms involved in the pathogenesis of AD. Moreover, AD often appears to be associated with psychological disorders such as alexithymia, depression, and anxiet

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Wu, Chieh-Shan, Shih-Chao Lin, Shiming Li, et al. "Phloretin alleviates dinitrochlorobenzene-induced dermatitis in BALB/c mice." International Journal of Immunopathology and Pharmacology 34 (January 2020): 205873842092944. http://dx.doi.org/10.1177/2058738420929442.

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Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient’s quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-derived phenolic compound, phloretin, to treat allergic contact dermatitis (ACD) on the dorsal skin of mice. In addition, the effectiveness of phloretin was evaluated using a mouse model of ACD triggered by 2,4-dinitrochlorobenzene (DNCB). In our experimental setting, phloretin was

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Athavale, Tejas Mahesh, Maddhusja Nalliah, Sybil Obuobi, Øystein Grimstad, and Nataša Škalko-Basnet. "Sustained release of betamethasone from solid lipid nanoparticles loaded polymeric hydrogels with natural emollient: One step closer to effective topical therapy for atopic dermatitis." Journal of Pharmaceutical Sciences 114, no. 8 (2025): 103876. https://doi.org/10.1016/j.xphs.2025.103876.

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Coghi, Paolo Saul, Yinghuai Zhu, Hongming Xie, Narayan S. Hosmane, and Yingjun Zhang. "Organoboron Compounds: Effective Antibacterial and Antiparasitic Agents." Molecules 26, no. 11 (2021): 3309. http://dx.doi.org/10.3390/molecules26113309.

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The unique electron deficiency and coordination property of boron led to a wide range of applications in chemistry, energy research, materials science and the life sciences. The use of boron-containing compounds as pharmaceutical agents has a long history, and recent developments have produced encouraging strides. Boron agents have been used for both radiotherapy and chemotherapy. In radiotherapy, boron neutron capture therapy (BNCT) has been investigated to treat various types of tumors, such as glioblastoma multiforme (GBM) of brain, head and neck tumors, etc. Boron agents playing essential

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Xue, Meilang, Haiyan Lin, Ruilong Zhao, Callum Fryer, Lyn March, and Christopher J. Jackson. "Activated Protein C Protects against Murine Contact Dermatitis by Suppressing Protease-Activated Receptor 2." International Journal of Molecular Sciences 23, no. 1 (2022): 516. http://dx.doi.org/10.3390/ijms23010516.

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Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with excessive inflammation and defective skin barrier function. Activated protein C (APC) is a natural anticoagulant with anti-inflammatory and barrier protective functions. However, the effect of APC on AD and its engagement with protease activated receptor (PAR)1 and PAR2 are unknown. Methods: Contact hypersensitivity (CHS), a model for human AD, was induced in PAR1 knockout (KO), PAR2KO and matched wild type (WT) mice using 2,4-dinitrofluorobenzene (DNFB). Recombinant human APC was administered into these mice as prev

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Tirant, Michael, Heather Tirant, and Uwe Wollina. "Herbal Bioactive Compounds for Skin Infections and Inflammatory Conditions." Open Access Macedonian Journal of Medical Sciences 12 (April 5, 2024): 1–44. http://dx.doi.org/10.3889/oamjms.2024.11888.

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Skin microbiota is an integral part of the human immune system. Staphylococcus aureus is one of the essential components of the normal flora. Approximately 20–30% of healthy individuals are persistently colonized with S. aureus, whereas the remainders are considered low-level intermittent carriers. Despite these natural aspects of existence, S. aureus can be a major opportunistic human pathogen. This versatile microorganism can infect a variety of anatomical sites, causing a broad spectrum of pathologies ranging from superficial to invasive infections. It developed a variety of strategies to a

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Megawati, Yunitasari, Retno Indar Widayati, and Diah Adriani Malik. "The Effect of Topical 100% Sunflower Seed Oil (SSO) Extract on Trans Epidermal Water Loss (Tewl) and Skin PH Levels in a History of Atopic Dermatitis." Jurnal Health Sains 5, no. 9 (2024): 742–58. http://dx.doi.org/10.46799/jhs.v5i9.1357.

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The skin barrier function can be disturbed in various conditions, one of which is atopic dermatitis (AD). Efforts to improve the skin barrier can be done by using various types of moisturizers. Natural oil from sunflower seed oil (SSO) can be used as "skin barrier therapy" by reducing trans epidermal water loss (TEWL) and skin pH levels. A randomized single blind clinical trial with a two parallel group pre and post design was conducted on subjects with a history of AD who were treated at the Skin and Venereology Polyclinic at Sunan Kalijaga Hospital, Demak. Samples were randomized into 2 grou

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Bolotna, L. A. "The use of the original enterosorbent in the complex treatment of chronic dermatoses." Ukrainian Journal of Dermatology, Venerology, Cosmetology, no. 1 (March 30, 2023): 31–37. https://doi.org/10.30978/ujdvk2023-1-31.

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The data on the formation of endogenous intoxication syndrome (EIS) as a multicomponent nonspecific process caused by the pathological activity of any endogenous products or the dysfunction of natural detoxification and biotransformation systems in skin diseases of various etiologies are presented. In patients with chronic dermatoses, this syndrome is characterized by the accumulation in the blood of products of disturbed metabolism (molecules of medium weight), the activation of lipid peroxidation and changes in the colonic resistance of the intestines.The presence of EIS, caused in particu

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Sahu, Narayan. "Conceptual Analysis of Vicharchika W.S.R to Eczema: An Overview." International Journal of Ayurveda and Herbal Research (IJAHR) 1, no. 2 (2023): 1–9. http://dx.doi.org/10.54060/ijahr.2023.15.

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Skin is the mirror image of body and mind, which is also the largest organ of body; it reflects physical, mental and physcho-logical state of an individual. Skin not only covers and protects the body but also performs some functions of excretion and metabolism. In the Ayurvedic texts all skin disorders are included under the Kushtaroga. Which is further classified in two divisions i.e. Mahakushta and Kshudrakushta, Vicharchika is one among them. Kushtha is one among Ashtamahagada al-so.Vicharchika is a type of kshudra kushta & Sadhya Kushtha by all acharya, often encountered by Ayurvedic D

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Fomina, Daria S., Olga A. Mukhina, Marina S. Lebedkina, et al. "Registry analysis of patients with severe allergic asthma and clinically relevant sensitization to fungal allergens treated with genetically engineered biologics." Consilium Medicum 24, no. 3 (2022): 170–76. http://dx.doi.org/10.26442/20751753.2022.3.201442.

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Background. Fungal sensitization (FS) often escapes the attention of clinicians when assessing the spectrum of sensitization in patients with atopic diseases. According to cohort studies is found in 310% of the general population and in 720% of asthmatics; the proportion of patients with severe bronchial asthma (SBA) with HS ranges from 35 to 75%. Fungal conidia have a 1000-fold higher exposure and are among the most important clinically relevant allergens in asthma. Exposure to fungal allergens is capable of generating a sustained T2 response with production of proinflammatory cytokines such

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Chavhan, Shankar* Daund Trupti Daund Prabhanjan Patil Pragati. "Formulation And Evaluation of Topical Polyherbal Emulgel for Treatment of Eczema." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 849–70. https://doi.org/10.5281/zenodo.15348093.

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Atopic dermatitis, commonly known as eczema, is a chronic inflammatory skin condition affecting millions worldwide. Characterized by itching, redness, and dryness, it significantly reduces quality of life and often requires long-term management. Conventional treatments such as corticosteroids, antihistamines, and immunosuppressants offer symptomatic relief but pose risks including side effects, dependency, and high costs. As a result, interest in herbal alternatives has increased due to their safety and potential efficacy.Neem (Azadirachta indica) and Aloe vera (Aloe barbadensis miller) are re

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Cerio, Rino. "Therapy of atopic dermatitis." Journal of the European Academy of Dermatology and Venereology 8, S1 (1997): S6—S10. http://dx.doi.org/10.1111/j.1468-3083.1997.tb01068.x.

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Hansen, Ronald C. "Therapy for atopic dermatitis." Current Opinion in Pediatrics 2, no. 4 (1990): 741–44. http://dx.doi.org/10.1097/00008480-199008000-00020.

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CERIO, R. "Therapy of atopic dermatitis." Journal of the European Academy of Dermatology and Venereology 8 (May 1997): S6—S10. http://dx.doi.org/10.1016/s0926-9959(97)90017-9.

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Senti, Gabriela, and Brunello Wüthrich. "Therapy of atopic dermatitis." Therapeutische Umschau 58, no. 5 (2001): 304–8. http://dx.doi.org/10.1024/0040-5930.58.5.304.

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Die atopische Dermatitis oder Neurodermitis ist eine stark juckende Hauterkrankung, die eine individuell angepasste Therapie benötigt. Es gibt verschiedene Behandlungsmöglichkeiten, die auf unterschiedlichen Ebenen ansetzen und sich auch mit gutem Erfolg kombinieren lassen. Da eine Kausaltherapie immer noch fehlt, kommt auch der Prävention bereits ab dem Säuglingsalter eine große Bedeutung zu. Nebst einer allergologischen Abklärung und Elimination der die Neurodermitis spezifisch verschlechternden Allergenen und Provokationsfaktoren (Reizstoffe im Haushalt und am Arbeitsplatz) ist die äußerlic

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Atanasov, Petar Yordanov, Maria Georgieva Moneva-Sakelarieva, Yozlem Ali Kobakova, et al. "Monoclonal antibodies: their place in applied medicine and their role in the newest infectious disease – history, present, and future. Literature review." Pharmacia 72 (June 25, 2025): 1–18. https://doi.org/10.3897/pharmacia.72.e159772.

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Monoclonal antibodies (mAbs) are immunoglobulins with practically absolute specificity (monospecificity) for a particular antigen (epitope). Over the past three decades, monoclonal antibodies have undergone a remarkable transformation, evolving from their use predominantly as research tools to becoming increasingly powerful therapeutic agents in medical practice. Personalized therapy and targeted treatment of diseases form the cornerstone of modern medicine’s revolutionary capabilities. Monoclonal antibodies are a shining example of personalized therapy, developed based on deep and continuousl

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Rothkopf, Michael. "Results of Histidine (His) Supplementation in a Case of Severe Nummular Eczema (NE)." Current Developments in Nutrition 4, Supplement_2 (2020): 1141. http://dx.doi.org/10.1093/cdn/nzaa055_026.

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Abstract Objectives NE (coin-shaped, severely pruritic skin lesions) is an idiopathic, histologically indistinguishable form of atopic dermatitis (AD). NE is chronic, relapsing and debilitating. Treatment is limited to skin moisturizers and anti-inflammatory agents. Recurrence is common. Recent studies suggest that lack of the protein, filaggrin (FLG) and its derivative natural moisturizing factors (NMFs) play a role. Because FLG is a His-rich compound, l-His supplementation (LHS) may provide a nutritional NE option. In this report, we present a patient with severe, resistant NE who responded

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Thomsen, Simon Francis. "Atopic Dermatitis: Natural History, Diagnosis, and Treatment." ISRN Allergy 2014 (April 2, 2014): 1–7. http://dx.doi.org/10.1155/2014/354250.

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Atopic dermatitis is an inflammatory skin disease with early onset and with a lifetime prevalence of approximately 20%. The aetiology of atopic dermatitis is unknown, but the recent discovery of filaggrin mutations holds promise that the progression of atopic dermatitis to asthma in later childhood may be halted. Atopic dermatitis is not always easily manageable and every physician should be familiar with the fundamental aspects of treatment. This paper gives an overview of the natural history, clinical features, and treatment of atopic dermatitis.

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Engler, D., F. Makola, and N. M. Magongwa. "Atopic Dermatitis." South African Family Practice 60, no. 6 (2018): 26–33. http://dx.doi.org/10.4102/safp.v60i6.4932.

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The aetiology of atopic dermatitis is multi-faceted and affects our first line host defence, the skin. Atopic dermatitis has a significant influence on a patient’s social and occupational functioning and can have long-lasting effects. The signs and symptoms of AD includes pruritus, erythema, fissuring, and lichenification – these are reduced by the use of moisturizing agents. Guidelines on how to manage atopic dermatitis aims to improve symptoms and achieve long-term disease control. Patient education remains as important as other treatment strategies and the pharmacist plays an integral role

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Ghazvini, Patty, Luis C. Pagan, Toby K. Rutledge, and H. Stewart Goodman. "Atopic Dermatitis." Journal of Pharmacy Practice 23, no. 2 (2010): 110–16. http://dx.doi.org/10.1177/0897190009360634.

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Atopic dermatitis (AD) is a common inflammatory skin disease with recurring episodes of itching and a chronic relapsing course. The prevalence of AD has increased exponentially over the years, along with information on how it may occur. Diagnosis of AD is typically based on physical examination and history and may be confirmed based on chronicity of symptoms, itching, and age-specific morphology. Nonpharmacological approaches include psychological interventions such as behavior modification, stress reduction techniques, and group psychotherapeutic treatments or may also include dietary restric

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Marshall, Leisa L. "Atopic Dermatitis in Adults: Focus on Topical Therapy." Senior Care Pharmacist 40, no. 3 (2025): 123–34. https://doi.org/10.4140/tcp.n.2025.123.

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Objective To review the topical therapies for adults, including older adults, with atopic dermatitis. A background on atopic dermatitis in adults, overview of treatment recommendations, and the pharmacists’ role for care is included. Data Sources Articles indexed in PubMed, Cochrane Reviews, and Google Scholar in the past 10 years using the search terms atopic dermatitis, atopic dermatitis and treatment, and atopic dermatitis and adults were reviewed. Current guidelines and manufacturers’ prescribing information were reviewed. Primary sources were used to locate additional resources. Study Sel

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Plzáková, Zuzana. "Maintenance Therapy in Atopic Dermatitis." Dermatologie pro praxi 12, no. 2 (2018): 64–68. http://dx.doi.org/10.36290/der.2018.011.

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Kinyó, Ágnes. "Topical therapy in atopic dermatitis." Bőrgyógyászati és Venerológiai Szemle 93, no. 5 (2017): 231–33. http://dx.doi.org/10.7188/bvsz.2017.93.5.6.

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