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Thèses sur le sujet « And dengue »

Auteur : Grafiati

Publié le 7 juin 2025

Mis à jour le 2 août 2025

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1

Borba, Luana de. "Dengue." reponame:Repositório Institucional da UFPR, 2011. http://hdl.handle.net/1884/26058.

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Paula, Eduardo Vedor de. "Dengue." reponame:Repositório Institucional da UFPR, 2013. http://hdl.handle.net/1884/1879.

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Tison, Laurence. "La dengue." Bordeaux 2, 1995. http://www.theses.fr/1995BOR2P091.

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Correa, Paulo Roberto Lopes. "Dengue e dengue hemorrágico em Belo Horizonte, 1996 - 2001." Universidade Federal de Minas Gerais, 2003. http://hdl.handle.net/1843/ECJS-84NP6V.

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Prevention and control of dengue and hemorrhagic dengue, currently the arbovirosis of greatest impact in terms of morbimortality in the population, depend basically on the reduction of the disease´s vector´s population in the domicile and peridomicile, the main locations where the transmission of the disease occurs. In order to analyze the occurrence of dengue in the city of Belo Horizonte and its relation with infestation rates of Aedes aegypti in the city´s buildings between the years 1996-2001, the building infestation rates IP (proportion of buildings which are positive for the vector´s l

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Brito, Carlos Alexandre Anturnes de. "Dengue em Recife, Pernambuco: padrões clínicos, epidemiológicos, laboratoriais e fatores de risco associados à forma grave da doença." reponame:Repositório Institucional da FIOCRUZ, 2007. https://www.arca.fiocruz.br/handle/icict/3908.

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Made available in DSpace on 2012-05-07T14:40:41Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 000008.pdf: 12182222 bytes, checksum: 6582644c03d01ced714c0dd1fdfc97c9 (MD5) Previous issue date: 2007<br>A tese será apresentada no formato de um capítulo de livro e quatro artigos para periódico. O capítulo do livro intitulado: Dengue e Febre Hemorrágica da Dengue, teve como objetivo realizar uma atualização do tema visando subsidiar os profissionais de saúde no suporte ao paciente com dengue. O primeiro artigo intitulado: Acute disseminated

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Prates, John Willians Oliveira. "Expressão das proteínas não-estrutural 1 (NS1) dos vírus Dengue-1, Dengue-3 e Dengue-4 em Pichia pastoris." Universidade Federal de Viçosa, 2017. http://www.locus.ufv.br/handle/123456789/21431.

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Submitted by Marco Antônio de Ramos Chagas (mchagas@ufv.br) on 2018-08-27T14:33:18Z No. of bitstreams: 1 texto completo.pdf: 789582 bytes, checksum: 2a1d5257736b2d9a9615f6069df6a707 (MD5)<br>Made available in DSpace on 2018-08-27T14:33:18Z (GMT). No. of bitstreams: 1 texto completo.pdf: 789582 bytes, checksum: 2a1d5257736b2d9a9615f6069df6a707 (MD5) Previous issue date: 2017-07-20<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A dengue é uma doença amplamente distribuída pelo mundo, e representa um grande problema de saúde pública em vários países. As manifestações clín

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Rolim, Meire Luce Moreira. "ClÃnical and laboratorial aspects of patients with serious forms of affection in Fortaleza - CearÃ." Universidade Federal do CearÃ, 2005. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=337.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>Dengue is an acute viral disease of varied clinical spectrum and of great epidemiological importance in Brazil, including CearÃ being Fortaleza a district in which the magnitude of the problem consists in concentrating a larger number of severe cases of the state. This research is about a descriptive study and prospective of secondary data of 103 cases of dengue registered in Fortaleza. The general objective was to describe profile of the platelets counting and of the hematÃcrito correlating them with the clinical evolut

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Leite, Priscila Leal e. "Impacto da dengue no Brasil em período epidêmico e não epidêmico : incidência, mortalidade, custo hospitalar e disability adjusted life years (DALY)." reponame:Repositório Institucional da UnB, 2015. http://repositorio.unb.br/handle/10482/19264.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Núcleo de Medicina Tropical, 2015.<br>Submitted by Patrícia Nunes da Silva (patricia@bce.unb.br) on 2016-01-15T15:44:32Z No. of bitstreams: 1 2015_PriscilaLealeLeite_Parcial.pdf: 268724 bytes, checksum: a29766f1345b28a4edfb4ea29f2ba98c (MD5)<br>Approved for entry into archive by Marília Freitas(marilia@bce.unb.br) on 2016-01-25T12:34:24Z (GMT) No. of bitstreams: 1 2015_PriscilaLealeLeite_Parcial.pdf: 268724 bytes, checksum: a29766f1345b28a4edfb4ea29f2ba98c (MD5)<br>Made available in DSpace on 2016-01-25T12:34:24Z (GMT).

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Tiew, Kok-Chuan. "Dengue virus protease inhibitors." Thesis, Wichita State University, 2011. http://hdl.handle.net/10057/6117.

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Dengue virus (DENV) is a major health threat that affects 2.5 billion people, or 40% of the world’s population. However, there are no approved antiviral drugs or vaccines to treat Dengue infection. This thesis describes the design, synthesis and discovery of a new class of inhibitors of DENV NS3 protease. Structure-activity relationship studies have been carried out in order to delineate the structural elements responsible for the activity of this series of compounds. A lead compound suitable for further development has been identified.<br>Thesis (M.S.)--Wichita State University, College of Li

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Cheong, Yoon Ling. "Dengue disease in Malaysia." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät, 2015. http://dx.doi.org/10.18452/17195.

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Der Klimawandel hat weitreichende Folgen auf die Gesundheit der Menschen. Insbesondere Übertragungskrankheiten wie Dengue bekommen global gesehen eine zunehmende Bedeutung. Über die raumzeitliche Verteilung und das Umwelt-Dengue Risiko ist bisher wenig bekannt. Das Hauptziel dieser Dissertation war es daher, die Ätiologie von Dengue in einem hoch endemischen Gebiet besser zu verstehen. Es wurden räumliche Muster des Krankheitsauftretens untersucht, die anschließend in einer Umwelt-Risiko Analyse mit örtlichen Wetterdaten und Landnutzungsinformationen in Zusammenhang gebracht wurden. Zunächst w

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Valadares, Adriane Feitosa. "CARACTERÍSTICAS EPIDEMIOLÓGICAS E AMBIENTAIS RELACIONADAS A DENGUE EM DUAS MAIORES CIDADES DO ESTADO DO TOCANTINS EM UM PERÍODO DE ONZE ANOS (2000 A 2010)." Pontifícia Universidade Católica de Goiás, 2012. http://localhost:8080/tede/handle/tede/2918.

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Made available in DSpace on 2016-08-10T10:53:41Z (GMT). No. of bitstreams: 1 ADRIANE FEITOSA VALADARES.pdf: 954155 bytes, checksum: a974324b3ec7a29cee64b580f03ab47f (MD5) Previous issue date: 2012-11-27<br>Dengue is a growing public health issue worldwide. As a result of their environmental, climatic and social characteristics, tropical countries are those most affected. The objectives of the present study conducted in the state of Tocantins, Brazil, were: to identify the demographic characteristics of notified and confirmed cases of dengue; to calculate the incidence rate of confirmed cases

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Flauzino, Regina Fernandes. "Dengue, heterogeneidade e indicadores sócioambientais: particularidades da dinâmica da dengue em nível local." reponame:Repositório Institucional da FIOCRUZ, 2009. https://www.arca.fiocruz.br/handle/icict/2546.

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Made available in DSpace on 2011-05-04T12:42:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2009<br>O presente estudo teve por objetivo analisar a distribuição temporal e espacial da dengue, no período de 1998 a 2006, utilizando a análise espacialaliada ao estudo de indicadores sócio-econômicos e ambientais como ferramenta para identificação de áreas prioritárias para o controle da dengue e contribuir para o aprimoramento dos métodos epidemiológicos para a identificação de características ambientais de risco de adoecer pela doença. O trabalho está apresentado em três artigos. No prime

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Gonçalves, Paula Fernanda. "Caracterização genômica de um vírus dengue tipo 3, isolado de paciente com dengue clássico." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-01042009-090555/.

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Dengue é uma doença infecciosa não contagiosa causada pelo vírus da dengue (gênero Flavivirus, família Flaviviridae), transmitida pela picada de artrópodes do gênero Aedes, principalmente Aedes aegypti, e sendo atualmente um importante problema de saúde pública em todo o mundo. Segundo a Organização Mundial de Saúde, cerca de 50 a 100 milhões de pessoas se infectam anualmente em mais de 100 países de todos os continentes. A dengue apresenta-se em três formas clínicas principais; doença febril indiferenciada, febre clássica do dengue (DF) e dengue hemorrágico com ou sem choque (DHF/DSS). Recent

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Buchinger, Diego. "Sherlock dengue 8: the Neighborhood - um jogo sério colaborativo-competitivo para combate à dengue." Universidade do Estado de Santa Catarina, 2014. http://tede.udesc.br/handle/handle/2044.

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Made available in DSpace on 2016-12-12T20:22:52Z (GMT). No. of bitstreams: 1 Diego Buchinger.pdf: 6508385 bytes, checksum: 43c3902c34434ea92c276412dcd6d710 (MD5) Previous issue date: 2014-11-27<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The dengue fever disease is a public health problem in many countries. Whilst efforts on creating a vaccine have been expended, the adopted practice for controlling this disease is raising the population awareness about this problem. Teaching to youngsters however, has proven a challenging task. In this sense, using Serious Games is a w

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Lindegren, Gunnel. "Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis." Stockholm : Department of Microbiology, Karolinska Institutet, 2008. http://diss.kib.ki.se/2008/978-91-7409-129-8/.

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16

Woodall, Hannah. "Structured models for dengue epidemiology." Thesis, University of Bath, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669027.

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Dengue is a vector-borne disease. Around 2.5 billion people are thought to be at risk of infection. It is spread primarily through the Aedes aegypti mosquito, and is endemic in tropical and subtropical regions. There are four distinct serotypes which co-circulate. Whilst infection from one serotype provides homologous immunity it does not provide heterologous immunity. In this thesis we use a range of modelling techniques to examine how the epidemiological dynamics of dengue are affected by immunological interaction between serotypes and age–dependent variation in the extent to which people ar

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Palacios, Cuervo Fernando, Rivera Andrea Calderón, Reyes Fátima Espinal, and Aybar Carlos Canelo. "Autoimmunity in dengue: Literature review." Elsevier B.V, 2015. http://hdl.handle.net/10757/595420.

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Palacios, Cuervo Fernando, Rivera Andrea Calderón, Reyes Fátima Espinal, and Aybar Carlos Canelo. "Autoimmunity in dengue: Literature review." Elsevier B.V, 2016. http://hdl.handle.net/10757/609496.

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Rosello, Nathalie. "La dengue et ses vecteurs." Paris 5, 1997. http://www.theses.fr/1997PA05P238.

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Edwards, Carolyn Jane. "Immunopathogenesis of dengue haemorrhagic fever." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/6840.

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This thesis aims to investigate human antibody responses to dengue virus. Dengue virus is a mosquito-borne flavivirus that circulates as 4 distinct serotypes in tropical and sub-tropical regions of the world. It is known that immunity to one serotype of the virus can be life-long but upon infection with a different serotype there is a much higher incidence of severe disease. Antibodies play an important role in this immunopathogenesis. Serotype cross-reactive antibodies have been shown to enhance the uptake of virus by Fc receptor-bearing host cells, thereby increasing the number of cells infe

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Rasheed, Syed Basit. "Dengue vector dynamics in Pakistan." Thesis, University of Sheffield, 2012. http://etheses.whiterose.ac.uk/2264/.

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During the last few year dengue has become an emerging vector borne disease in Pakistan. Aedes aegypti once considered eradicated from almost whole of Pakistan was again collected from 13 different cities. This mosquito has not only started reinvading its previously occupied areas (Karachi, Peshawar and Lahore) but is also spreading to new areas where it was not present before (Attock, Haripur, Hasanabdal, Taxilla, Rawalpindi, Gujranwala, Sheikhupura, Faisalabad, Multan and Hyderabad). This mosquito is breeding in almost all types of artificial containers especially in tyres. Though this mosqu

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Rocha, Benigno Alberto Moraes da. "Aspectos clínicos e moleculares da dengue na epidemia de 2012/ 2013 em Goiânia – GO, Brasil." Universidade Federal de Goiás, 2015. http://repositorio.bc.ufg.br/tede/handle/tede/6599.

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Submitted by JÚLIO HEBER SILVA (julioheber@yahoo.com.br) on 2016-12-14T17:53:04Z No. of bitstreams: 2 Tese - Benigno Alberto Moraes da Rocha - 2015.pdf: 2182475 bytes, checksum: 33c24230875842c1d6d2b9260ba26f6e (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Jaqueline Silva (jtas29@gmail.com) on 2016-12-15T17:34:35Z (GMT) No. of bitstreams: 2 Tese - Benigno Alberto Moraes da Rocha - 2015.pdf: 2182475 bytes, checksum: 33c24230875842c1d6d2b9260ba26f6e (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br

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Dinayadura, Nirosha. "An Efficient Approach for Dengue Mitigation: A Computational Framework." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1505177/.

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Dengue mitigation is a major research area among scientist who are working towards an effective management of the dengue epidemic. An effective dengue mitigation requires several other important components. These components include an accurate epidemic modeling, an efficient epidemic prediction, and an efficient resource allocation for controlling of the spread of the dengue disease. Past studies assumed homogeneous response pattern of the dengue epidemic to climate conditions throughout the regions. The dengue epidemic is climate dependent and also it is geographically dependent. A global mo

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Nunes, Juliana da Silva. "Dengue: etiologia, patogénese e suas implicações a nível global." Master's thesis, Universidade da Beira Interior, 2011. http://hdl.handle.net/10400.6/977.

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A doença causada pelo vírus do Dengue tornou-se uma das principais doenças infecciosas emergentes a nível mundial, sendo agora considerada uma epidemia global e registada em mais de 120 países. Tal facto põe em risco grande parte da população mundial. O vírus do Dengue pertence ao grupo das arboviroses, referente a família Flaviviridae, género Flavivírus, possui quatro serotipos geneticamente e antigenicamente distintos (1-4). Transmitido ao homem através da picada de mosquitos hematófagos fêmeas do género Aedes, principalmente o Aedes Aegypti e Aedes Albopictus. Ambos possuem disseminação a

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O'Neill, Shannon M. "The Effect of Changing Environmental Factors on the Resurgence of Dengue Fever and Severe Dengue." Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/cmc_theses/1308.

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Throughout the early twentieth century, dengue fever was considered to be a nonthreatening illness, only infecting visitors of the tropics. However, in the last fifty years, there has been a resurgence of dengue fever; it is now considered to be the most consequential arbovirus, infecting more than 50 million people each year and leaving about half of the world's current population at risk of infection. The purpose of this thesis is to explore the various environmental factors that have contributed to the resurgence of dengue fever that has been seen in the last half century. Most notable of t

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Cordeiro, Marli Tenório. "Evolução da dengue no estado de Pernambuco, 1987-2006: epidemiologia e caracterização molecular dos sorotipos circulantes." reponame:Repositório Institucional da FIOCRUZ, 2008. https://www.arca.fiocruz.br/handle/icict/3890.

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Made available in DSpace on 2012-05-07T14:40:38Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 000011.pdf: 3402351 bytes, checksum: 815d847349c1018a30585a34805422bf (MD5) Previous issue date: 2008<br>Em Pernambuco, o primeiro surto de dengue ocorreu em 1987, pelo sorotipo 1. Em 1995, após sete anos sem notificação da doença, ocorreu nova epidemia causada pelo sorotipo 2. Em 2002, após a introdução do sorotipo 3, circularam simultaneamente os três sorotipos. Nesta tese são apresentados aspectos epidemiológicos, clínicos e laboratoriais d

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Marques, Solomar Martins. "Fatores de risco para complicações por dengue em menores de 15 anos no município de Goiânia." Universidade Federal de Goiás, 2013. http://repositorio.bc.ufg.br/tede/handle/tede/3651.

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Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-11-20T11:26:09Z No. of bitstreams: 2 Tese - Solomar Martins Marques - 2013.pdf: 2691124 bytes, checksum: 04ee7837e335b7d3d617e5d8fe652956 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2014-11-20T11:26:37Z (GMT) No. of bitstreams: 2 Tese - Solomar Martins Marques - 2013.pdf: 2691124 bytes, checksum: 04ee7837e335b7d3d617e5d8fe652956 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Made

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Lima, Maria Cristina Aguiar. "Dengue com complicações no Estado da Bahia: uma revisão a luz dos critérios da OMS (1997 e 2009)." Instituto de Saúde Coletiva, 2010. http://repositorio.ufba.br/ri/handle/ri/27096.

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Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2018-08-27T13:28:47Z No. of bitstreams: 1 Diss MP Maria Cristina Aguiar Lima. 2010.pdf: 701637 bytes, checksum: 958fbfe399cafe951de515c1c37529bf (MD5)<br>Approved for entry into archive by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2018-08-27T14:06:47Z (GMT) No. of bitstreams: 1 Diss MP Maria Cristina Aguiar Lima. 2010.pdf: 701637 bytes, checksum: 958fbfe399cafe951de515c1c37529bf (MD5)<br>Made available in DSpace on 2018-08-27T14:06:47Z (GMT). No. of bitstreams: 1 Diss MP Maria Cristina Aguiar Lima. 2010.pdf: 701637 bytes, che

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Maria, Azevedo de Lyra Juliana. "Caracterização genética de isolados virais da dengue." Universidade Federal de Pernambuco, 2006. https://repositorio.ufpe.br/handle/123456789/6334.

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Made available in DSpace on 2014-06-12T18:04:19Z (GMT). No. of bitstreams: 2 arquivo6193_1.pdf: 776005 bytes, checksum: 030afd1b5bece89b5fb9295c3e29f930 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2006<br>A caracterização molecular do vírus da dengue é útil na determinação da origem de amostras e, principalmente, na tentativa de se estabelecer uma correlação de virulência dos isolados e sua importância epidemiológica. Embora os quatro sorotipos do vírus da dengue possam causar a febre hemorrágica da dengue considerando a infecção p

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Rolim, Meire Luce Moreira. "Aspectos clínico-laboratoriais de pacientes com formas graves de dengue em Fortaleza, Ce." reponame:Repositório Institucional da UFC, 2005. http://www.repositorio.ufc.br/handle/riufc/1333.

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ROLIM, Meire Luce Moreira. Aspectos clínico-laboratoriais de pacientes com formas graves de dengue em Fortaleza, Ce. 2005. 141 f. Dissertação (Mestrado em Saúde Pública) - Universidade Federal do Ceará, Fortaleza, 2005.<br>Submitted by denise santos (denise.santos@ufc.br) on 2011-11-08T14:12:52Z No. of bitstreams: 1 2005_dis_mlmrolim.pdf: 1699008 bytes, checksum: d6b9c4810f467805af50196824687fb0 (MD5)<br>Approved for entry into archive by Eliene Nascimento(elienegvn@hotmail.com) on 2011-12-05T13:13:46Z (GMT) No. of bitstreams: 1 2005_dis_mlmrolim.pdf: 1699008 bytes, checksum: d6b9c4810f467805a

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Gomes, Almira Maria Monteiro. "Avaliação dos aspectos clínicos e laboratoriais no diagnóstico de pacientes com suspeita de dengue em Fortaleza-Ceará, 2010." reponame:Repositório Institucional da UFC, 2012. http://www.repositorio.ufc.br/handle/riufc/6881.

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GOMES, Almira Maria Monteiro. Avaliação dos aspectos clínicos e laboratoriais no diagnóstico de pacientes com suspeita de dengue em Fortaleza-Ceará, 2010. 2012. 99 f. Dissertação (mestrado em Patologia) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2012.<br>Submitted by denise santos (denise.santos@ufc.br) on 2013-12-03T11:11:09Z No. of bitstreams: 1 2012_dis_ammgomes.pdf: 2429107 bytes, checksum: 202d0adce0955d06fa7cd3484f9e2d93 (MD5)<br>Approved for entry into archive by denise santos(denise.santos@ufc.br) on 2013-12-03T11:13:24Z (GMT) No. of bitstreams: 1 2012_dis_ammg

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Silva, Francisco Marcio Pereira da. "Investigação de poliformismo nos genes das citocinas TNFa, INFg, TGfb, IL-6 e IL-10 em pacientes com febre hemorrágica da dengue." reponame:Repositório Institucional da UFC, 2010. http://www.repositorio.ufc.br/handle/riufc/15427.

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SILVA, Francisco Marcio Pereira da. Investigação de poliformismo nos genes das citocinas TNFa, INFg, TGfb, IL-6 e IL-10 em pacientes com febre hemorrágica da dengue. 2010. 68 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2010.<br>Submitted by denise santos (denise.santos@ufc.br) on 2016-03-09T15:19:11Z No. of bitstreams: 1 2010_dis_fmpsilva.pdf: 1000041 bytes, checksum: ed8a0829820ab0378a44784409d70332 (MD5)<br>Approved for entry into archive by denise santos(denise.santos@ufc.br) on 2016-03-09T15:45:00Z (GMT) No. of bitstreams: 1 201

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ROCHA, Benigno Alberto Moraes. "Perfil clínico-epidemiológico da dengue em menores de 15 anos de idade, no município de Goiânia Goiás." Universidade Federal de Goiás, 2008. http://repositorio.bc.ufg.br/tede/handle/tde/1797.

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Made available in DSpace on 2014-07-29T15:30:35Z (GMT). No. of bitstreams: 1 Dissertacao de Benigno Alberto Moraes Rocha.pdf: 429604 bytes, checksum: e7166c606b960cf25df199a5ddc928fd (MD5) Previous issue date: 2008-02-29<br>In Brazil, dengue is present in almost all states and territories, with a circulation of three different serotypes (DEN 1, DEN 2 and DEN 3), resulting in about 500 000 cases reported in 2007 (PAHO 2008; MS / SVS 2008a). This dissertation consists of a literature review, with emphasis on the epidemiology of dengue in Brazil and two articles that are designed to analyze the

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Silva, Andréa Nazaré Monteiro Rangel da. "Desenvolvimento e avaliação de duas novas estratégias vacinais contra o vírus da Dengue." Centro de Pesquisas Aggeu Magalhães, 2011. https://www.arca.fiocruz.br/handle/icict/10596.

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Made available in DSpace on 2015-06-01T19:28:11Z (GMT). No. of bitstreams: 2 536.pdf: 12060845 bytes, checksum: 5af1c56abad31cc9c82bc99e14652b56 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011<br>Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil<br>A dengue é um problema de Saúde Pública em termos de morbidade e mortalidade, sendo reconhecida em mais de 100 países. No entanto, o desenvolvimento de uma vacina encontra sua dificuldade na imunopatogênese da doença, fazendo-se necessária a construção de uma va

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Alves, Rúbens Prince dos Santos. "Desenvolvimento de uma vacina de subunidade contra o sorotipo 2 do vírus dengue baseada na proteína não estrutural 5 (NS5)." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-06102015-193757/.

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A dengue é uma doença que afeta milhões de pessoas e possui um número significativo de mortes. Não há nenhum tratamento vacinal legalizado para uso. As estratégias vacinais contra a dengue baseadas em proteínas não estruturais têm demonstrado serem mais seguras do que as baseadas em proteínas estruturais. A proteína não estrutural 5 (NS5) do vírus dengue é a proteína mais conservada entre os quatro sorotipos e desempenha um papel crucial na replicação viral. Neste estudo, foi gerada uma forma recombinante da NS5 expressa em E. coli com propriedades antigênicas preservados. As condições de cult

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Bizerra, Raíza Sales Pereira. "Desenvolvimento de uma vacina de subunidade contra o sorotipo 2 do vírus dengue baseada no domínio helicase da proteína NS3." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-28112014-101433/.

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O desenvolvimento de uma vacina para o controle da dengue é uma prioridade em todo o mundo. O domínio helicase da proteína NS3 (NS3H) viral alberga epítopos reconhecidos por linfócitos T citotóxicos, os quais tem papel importante na eliminação de células infectadas. Esse trabalho propôs a obtenção de uma forma recombinante, produzida em linhagens de Escherichia coli, da NS3H do DENV2 com características similares à proteína nativa e sua utilização como um potencial antígeno vacinal. A NS3H foi obtida na forma solúvel, foi reconhecida por anticorpos de camundongos e de humanos infectados e foi

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Guollo, Dirce Sayuri Otake. "CARACTERÍSTICAS EPIDEMIOLÓGICAS RELACIONADAS AOS CASOS DE DENGUE DIAGNOSTICADOS NO MUNICÍPIO DE CUIABÁ - MATO GROSSO, 2007 A 2011." Pontifícia Universidade Católica de Goiás, 2013. http://localhost:8080/tede/handle/tede/2958.

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Made available in DSpace on 2016-08-10T10:54:10Z (GMT). No. of bitstreams: 1 DIRCE SAYURI OTAKE GUOLLO.pdf: 1073948 bytes, checksum: 3c37949ac45c5ba805d30bc1620419a0 (MD5) Previous issue date: 2013-11-01<br>Introduction: Dengue is one of the arboviruses that mostly affects people worldwide, with its early diagnosis and treatment being necessary to avoid complications that may lead to death. Objective: Describe cases of dengue as per demographic aspects; analyze the evolution of morbimortality in the cases of dengue reported and describe the spatial distribution of deaths by dengue. Methodolo

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Tran, Tuan Anh. "Screening against the dengue virus polymerase." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4006.

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La dengue, une des maladies les plus largement émergents actuellement, avec 390 millions d'infections chaque année (OMS), est causée par le virus de la dengue contre lequel il n’existe pas de traitements. La protéine NS5 a un rôle important dans le cycle de réplication. Cette protéine se compose d'une méthionine S-transférase d’adénosyl en N-terminal et une ARN polymérase dépendante de l'ARN (RdRp) en C-terminal. Cette NS5 RdRp peut catalyser non seulement la synthèse du brin négatif de l'ARN, utilisé comme matrice pour synthétiser l'ARN brin plus-supplémentaire, mais aussi pour la synthèse d'

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Bannwart, Bettina Fiorini [UNESP]. "Otimização multiobjetivo no controle da dengue." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/108598.

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Made available in DSpace on 2014-08-13T14:50:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-12-16Bitstream added on 2014-08-13T18:00:36Z : No. of bitstreams: 1 000757973.pdf: 741216 bytes, checksum: 92e333cd37d629a776fed1e9c2889fa3 (MD5)<br>A dengue é uma doença infecciosa febril aguda causada por um vírus da família Flaviridae e é transmitida através de mosquito, comumente do gênero Aedes Aegypti. Esta doença tem sido atualmente um problema mundial de saúde pública, pois em 45 dias de vida um único mosquito pode contaminar até 300 pessoas e existe uma estimativa da Organização Mu

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He, Runtao. "Characterization of dengue virus envelope protein." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq24745.pdf.

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Bartley, Lucy Margaret Antonia. "The transmission dynamics of dengue infections." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343215.

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Quyen, Nguyen Than Ha. "Diagnosis and prognosis of severe dengue." Thesis, Open University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539411.

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Jayathunga, Yashika [Verfasser]. "Multi-patch Dengue Models / Yashika Jayathunga." München : Verlag Dr. Hut, 2019. http://d-nb.info/1202168507/34.

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MACHADO, Larissa Santos. "Controle de um modelo para dengue." Universidade Federal de Pernambuco, 2017. https://repositorio.ufpe.br/handle/123456789/25149.

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Submitted by Pedro Barros (pedro.silvabarros@ufpe.br) on 2018-07-19T20:57:28Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Larissa Santos Machados.pdf: 758712 bytes, checksum: bd9e8b595c243e8025be1c3871bf6d5f (MD5)<br>Approved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-07-20T21:55:10Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Larissa Santos Machados.pdf: 758712 bytes, checksum: bd9e8b595c243e8025be1c3871bf6d5f (MD5)<br>Made available in

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Bannwart, Bettina Fiorini. "Otimização multiobjetivo no controle da dengue /." Botucatu, 2013. http://hdl.handle.net/11449/108598.

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Orientador: Helenice de Oliveira Florentino Silva<br>Coorientador: Daniela Renata Cantane<br>Banca: Adriana Cristina Cherri Nicola<br>Banca: Andrea Carla Gonçalves Vianna<br>Resumo: A dengue é uma doença infecciosa febril aguda causada por um vírus da família Flaviridae e é transmitida através de mosquito, comumente do gênero Aedes Aegypti. Esta doença tem sido atualmente um problema mundial de saúde pública, pois em 45 dias de vida um único mosquito pode contaminar até 300 pessoas e existe uma estimativa da Organização Mundial da Saúde (OMS) que anualmente de 50 a 100 milhões de pessoas se in

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Meesumrarn, Thiraphat. "Simulation of Dengue Outbreak in Thailand." Thesis, University of North Texas, 2018. https://digital.library.unt.edu/ark:/67531/metadc1248484/.

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The dengue virus has become widespread worldwide in recent decades. It has no specific treatment and affects more than 40% of the entire population in the world. In Thailand, dengue has been a health concern for more than half a century. The highest number of cases in one year was 174,285 in 1987, leading to 1,007 deaths. In the present day, dengue is distributed throughout the entire country. Therefore, dengue has become a major challenge for public health in terms of both prevention and control of outbreaks. Different methodologies and ways of dealing with dengue outbreaks have been put forw

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Nikin-Beers, Ryan Patrick. "Immunoepidemiological Modeling of Dengue Viral Infection." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/82924.

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Dengue viral infection is a mosquito-borne disease with four distinct strains, where the interactions between these strains have implications on the severity of the disease outcomes. The two competing hypotheses for the increased severity during secondary infections are antibody dependent enhancement and original antigenic sin. Antibody dependent enhancement suggests that long-lived antibodies from primary infection remain during secondary infection but do not neutralize the virus. Original antigenic sin proposes that T cells specific to primary infection dominate cellular immune responses dur

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Nikin-Beers, Ryan Patrick. "Mathematical Modeling of Dengue Viral Infection." Thesis, Virginia Tech, 2014. http://hdl.handle.net/10919/48594.

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In recent years, dengue viral infection has become one of the most widely-spread mosquito-borne diseases in the world, with an estimated 50-100 million cases annually, resulting in 500,000 hospitalizations. Due to the nature of the immune response to each of the four serotypes of dengue virus, secondary infections of dengue put patients at higher risk for more severe infection as opposed to primary infections. The current hypothesis for this phenomenon is antibody-dependent enhancement, where strain-specific antibodies from the primary infection enhance infection by a heterologous serotype. To

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Perez, De Los Santos Diego. "Control vectorial del dengue: revisión bibliográfica." Bachelor's thesis, Universidad Católica Santo Toribio de Mogrovejo, 2019. http://hdl.handle.net/20.500.12423/3115.

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Objetivo: Describir el control vectorial del dengue. Método: La investigación fue una revisión bibliográfica de tipo descriptiva, que permitió hallar, organizar y sintetizar la información encontrada acerca del control vectorial del dengue. La búsqueda bibliográfica se realizó entre los meses de mayo a julio del 2020 en diversas fuentes. Algunas diversas bases como: Pubmed y el motor de búsqueda Google académico. Para la estrategia exacta de búsqueda se utilizaron descriptores en español e inglés y operadores boléanos “AND” y “OR”, combinándolos de diferente forma: (Control AND dengue), (Contr

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Chartree, Jedsada. "Monitoring Dengue Outbreaks Using Online Data." Thesis, University of North Texas, 2014. https://digital.library.unt.edu/ark:/67531/metadc500167/.

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Internet technology has affected humans' lives in many disciplines. The search engine is one of the most important Internet tools in that it allows people to search for what they want. Search queries entered in a web search engine can be used to predict dengue incidence. This vector borne disease causes severe illness and kills a large number of people every year. This dissertation utilizes the capabilities of search queries related to dengue and climate to forecast the number of dengue cases. Several machine learning techniques are applied for data analysis, including Multiple Linear Regressi

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