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1

Miller, Janine D. "Anti-aging therapeutic agents." Journal of the American Academy of Dermatology 50, no. 3 (2004): P25. http://dx.doi.org/10.1016/j.jaad.2003.10.105.

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Blagosklonny, Mikhail V. "Selective anti-cancer agents as anti-aging drugs." Cancer Biology & Therapy 14, no. 12 (2013): 1092–97. http://dx.doi.org/10.4161/cbt.27350.

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Lestari, Diah Ayu, and Novi Febrianti. "Topical Pharmacological Agents That Have Anti-Aging Properties." Symposium on Biology Education (Symbion) 3 (July 8, 2023): 32. http://dx.doi.org/10.26555/symbion.11685.

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Aging of the skin is a common problem today, the effects of aging skin cause insecurity due to changes due to various factors. Aging is the process of progressively reducing the function and capacity of the skin. Effects of aging such as wrinkles, fine lines, hyperpigmentation, sagging skin and dark blemishes. The method used in this study is a search of relevant literature collected from various studies that have been published in google scholar, Elsevier, and pubmed related to anti-aging. To reduce the effects of aging on the skin, cosmetic pharmaceutical products are developed known as anti
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Yalcin, Gulperi, and Cheol-Koo Lee. "The Discovery of Druggable Anti-aging Agents." Annals of Geriatric Medicine and Research 24, no. 4 (2020): 232–42. http://dx.doi.org/10.4235/agmr.20.0092.

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Liu, Ying, Minglv Fang, Xiaohui Tu, et al. "Dietary Polyphenols as Anti-Aging Agents: Targeting the Hallmarks of Aging." Nutrients 16, no. 19 (2024): 3305. http://dx.doi.org/10.3390/nu16193305.

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Background: Aging is a natural biological process influenced by multiple factors and is a significant contributor to various chronic diseases. Slowing down the aging process and extending health span have been pursuits of the scientific field. Methods: Examination of the effects of dietary polyphenols on hallmarks of aging such as genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammati
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Rolle, Katarzyna, Wojciech T. Markiewicz, and Jan Barciszewski. "Modified nucleic acids as an anti-aging agents." BioTechnologia 95, no. 4 (2015): 264–66. https://doi.org/10.5114/bta.2014.56597.

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The subject of the invention is the use of 4-furfurylcytosine and /or its derivatives in anti-aging compositions. As 4-furfurylcytosine and /or its derivatives possesses a series of biological properties it might be use as a composition having excellent anti-aging effect to prevent the sagging of skin and loss of luster and to improve sufficiently its aesthetic appearance without significantly change the growth rate and the total growth ability of the skin.
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Permatasari, Agita Dyah, Yandi Syukri, and Sista Werdyani. "Gold Nanoparticles with Natural Ingredients as Anti-Aging: A Systematic Review." Journal of Pharmaceutical Sciences and Community 20, no. 1 (2023): 90–113. http://dx.doi.org/10.24071/jpsc.004374.

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Aging is a natural process characterized by physiological skin changes. It starts to appear when individuals are in their thirties, making it necessary to use anti-aging products with natural ingredients which are safe even though the penetration is relatively low into the skin. Natural ingredients that can be used are antioxidants that can inhibit aging and can act as bioreductants on gold nanoparticles. Gold nanoparticles can increase penetration into the target cells because of their small size with large surface area. This review article aimed to collect data relating to the development of
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Shu, Shiqi, Chuanyi Zhuang, Shuqian Zhao, Yan Hao, Hao Guo, and Yali Ye. "Study of Anti-Stripping Measures to Improve the Adhesion of Asphalt to Granite Aggregates." Coatings 12, no. 12 (2022): 1954. http://dx.doi.org/10.3390/coatings12121954.

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Granite is very widely distributed in the world, but granite is an acidic aggregate with poor adhesion to asphalt. In untreated asphalt mixtures, asphalt pavement water damage and loose disease are more prominent, affecting the service life of the pavement and service level. Enhancing the road performance of granite asphalt mixture generally improves the adhesion properties of asphalt and granite. Qingchuan rock asphalt, anti-stripping agent KH5, aliphatic amine anti-stripping agent AJ-1 and two groups of the composite anti-stripping agents were used to modify the asphalt and analyze the effec
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Ahmed, Amr. "Insulin Sensitizers as Anti-Aging Agents: Unveiling Synergies with Albumin, GLP-1RA, Klotho Protein, and Metformin in the Quest to Combat Aging." Cell & Cellular Life Sciences Journal 9, no. 1 (2024): 1–5. http://dx.doi.org/10.23880/cclsj-16000200.

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This study delves into the synergistic interplay among albumin, insulin, Klotho protein, and relevant medications in the pursuit of a concerted approach to halt aging. Emphasizing albumin's pivotal role in various physiological functions, including transportation and drug distribution, the research underscores its decline's correlation with aging-related cognitive implications. The intricate relationship between insulin and albumin, modulated by Foxo1, underscores its crucial significance. Groundbreaking experiments, utilizing unmodified serum albumin, demonstrate a remarkable increase in life
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Lestari, Uce, Muhaimin Muhaimin, Anis Yohana Chaerunisaa, and Wawan Sujarwo. "Anti-Aging Potential of Plants of the Anak Dalam Tribe, Jambi, Indonesia." Pharmaceuticals 16, no. 9 (2023): 1300. http://dx.doi.org/10.3390/ph16091300.

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The process of skin aging is a physiological phenomenon that can not be avoided. According to global population data, the rate of aging increases by approximately 13% every year. The impact of skin aging has become a significant concern and challenge for developed countries. Consequently, there has been a search for potential new anti-aging agents. This review aims to provide an overview of the current research status of plants of the Anak Dalam Tribe (Indonesian: Suku Anak Dalam [SAD]; referred to as SAD henceforth) in Jambi Province, Indonesia, for the development of potential new anti-aging
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Moghimipour, Eskandar. "Hydroxy Acids, the Most Widely Used Anti-aging Agents." Jundishapur Journal of Natural Pharmaceutical Products 7, no. 1 (2012): 9–10. http://dx.doi.org/10.17795/jjnpp-4181.

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Moghimipour, Eskandar. "Hydroxy Acids, the Most Widely Used Anti-aging Agents." Jundishapur Journal of Natural Pharmaceutical Products 7, no. 1 (2012): 9–10. http://dx.doi.org/10.5812/jjnpp.4181.

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Moghimipour, Eskandar. "Hydroxy Acids, the Most Widely Used Anti-aging Agents." jundishapur Jornal of Natural Pharmaceutical Products 6, no. 2 (2012): 9–10. http://dx.doi.org/10.5812/kowsar.17357780.4181.

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Zaid, Abdel Naser, and Rowa’ Al Ramahi. "Depigmentation and Anti-aging Treatment by Natural Molecules." Current Pharmaceutical Design 25, no. 20 (2019): 2292–312. http://dx.doi.org/10.2174/1381612825666190703153730.

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Natural molecules are becoming more accepted choices as cosmetic agents, many products in the market today claim to include natural components. Plants include many substances that could be of a value in the whitening of the skin and working as anti-aging agents. A wide range of articles related to natural skin whitening and anti-aging agents have been reviewed. Many plant-derived and natural molecules have shown to affect melanin synthesis by different mechanisms, examples include Arbutin, Ramulus mori extract, Licorice extract, Glabridin, Liquiritin, Kojic acid, Methyl gentisate, Aloesin, Aze
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Fu, Chunping, Zhen Wang, Shanglin Song, et al. "Experimental Study on Anti-Aging Effect of Asphalt Binder Liquid Anti-Aging Agent." Buildings 14, no. 4 (2024): 1023. http://dx.doi.org/10.3390/buildings14041023.

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During its service life, asphalt pavement is affected by environmental factors such as heat, light, oxygen and moisture. The asphalt binder ages, resulting in a decrease in the performance of the asphalt pavement. Therefore, the development and application of an asphalt anti-aging agent is of great significance. In this paper, the road performance of the developed asphalt binder liquid anti-aging agent was verified in the two scales of asphalt binder and asphalt mixture, respectively. Firstly, a simple aging test method was proposed using needle penetration as the evaluation index. The aging t
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Novotná, Renáta, Denisa Škařupová, Jiří Hanyk, et al. "Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents." Molecules 28, no. 4 (2023): 1728. http://dx.doi.org/10.3390/molecules28041728.

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Aging is a complex physiological process that can be accelerated by chemical (high blood glucose levels) or physical (solar exposure) factors. It is accompanied by the accumulation of altered molecules in the human body. The accumulation of oxidatively modified and glycated proteins is associated with inflammation and the progression of chronic diseases (aging). The use of antiglycating agents is one of the recent approaches in the preventive strategy of aging and natural compounds seem to be promising candidates. Our study focused on the anti-aging effect of the flavonoid hesperetin, its glyc
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He, Zhengwei, Dongdong Ge, Jianping Xian, et al. "Performance Comparison of Different Types of Anti-UV Aging Agents in Modified Asphalt." Buildings 15, no. 3 (2025): 360. https://doi.org/10.3390/buildings15030360.

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There are many types of asphalt anti-UV aging agents, and the differences in their UV resistance mechanisms result in varying degrees of UV aging resistance. This study utilized three types of anti-UV aging agents to modify asphalt. These include a UV reflector (TiO2), a hindered amine light stabilizer (HALS, LS770), and a UV absorber (UV326). The contents were 0.5%, 1%, and 1.5%. When the dosages of TiO2, LS770, and UV326 were 1.5%, the rutting factors of the modified asphalt at 64 °C increased by 61.18%, 43.54%, and 34.18%, respectively. As the dosage of LS770 and TiO2 increased, the rutting
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Kowalczyk, Tomasz, Anna Merecz-Sadowska, Mansour Ghorbanpour, et al. "Enhanced Natural Strength: Lamiaceae Essential Oils and Nanotechnology in In Vitro and In Vivo Medical Research." International Journal of Molecular Sciences 24, no. 20 (2023): 15279. http://dx.doi.org/10.3390/ijms242015279.

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The Lamiaceae is one of the most important families in the production of essential oils known to have a wide spectrum of biological activity. Recent research has highlighted the dermatological capabilities of various Lamiaceae essential oils, which appear to offer potential in free radical scavenging and anti-inflammatory activity. Some have also been extensively studied for their tissue remodeling and wound-healing, anti-aging, anti-melanogenic, and anti-cancer properties. Certain Lamiaceae essential oils are promising as novel therapeutic alternatives for skin disorders. This potential has s
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Amakye, William Kwame, Chuanli Hou, Liping Xie, et al. "Bioactive anti-aging agents and the identification of new anti-oxidant soybean peptides." Food Bioscience 42 (August 2021): 101194. http://dx.doi.org/10.1016/j.fbio.2021.101194.

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Chung, Ku Bong, Ki Byung Kim, Sang Sub Lee, and Woo Sung Kim. "Anti-aging effects of liquid and solid anti-stripping agents on asphalt binders." International Journal of Highway Engineering 22, no. 2 (2020): 33–39. http://dx.doi.org/10.7855/ijhe.2020.22.2.033.

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Bhattacharyya, Tapan K., Natalie P. Higgins, J. Scott Sebastian, and J. Regan Thomas. "R401 – Anti-Aging Compounds and Epidermal Effects on Mouse Skin." Otolaryngology–Head and Neck Surgery 139, no. 2_suppl (2008): P177. http://dx.doi.org/10.1016/j.otohns.2008.05.554.

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Problem To compare topical effects of 5 anti-aging agents on epidermal histology in the non-irradiated hairless mouse. Methods Female retired breeders (SKH-1 hairless mouse) were treated topically on the dorsal skin with 5 commercially available agents as a daily treatment for 2 weeks. The agents used were retinoic acid, glycolic acid, estrogen, soy, and vitamin C. Skin sections were analyzed in the light microscope to acquire morphometric data of keratinocyte proliferation (Index of Proliferating Cell Nuclear Antigen), epidermal thickness, and nuclear volume of cells from three epidermal laye
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Hu, Zhihui, Tao Xu, Pengfei Liu, Markus Oeser, and Haopeng Wang. "Improvements of Developed Graphite Based Composite Anti-Aging Agent on Thermal Aging Properties of Asphalt." Materials 13, no. 18 (2020): 4005. http://dx.doi.org/10.3390/ma13184005.

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To reduce the thermal-oxidative aging of asphalt and the release amount of harmful volatiles during the construction of asphalt pavement, a new composite anti-aging agent was developed. Since the volatiles were mainly released from saturates and aromatics during the thermal-oxidative aging of asphalt, expanded graphite (EG) was selected as a stabilizing agent to load magnesium hydroxide (MH) and calcium carbonate (CaCO3) nanoparticles for preparing the anti-aging agents of saturates and aromatics, respectively. Thermal stability and volatile constituents released from saturates and aromatics b
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Kim, Sun Kyung, Peter C. Goughnour, Eui Jin Lee, et al. "Identification of drug combinations on the basis of machine learning to maximize anti-aging effects." PLOS ONE 16, no. 1 (2021): e0246106. http://dx.doi.org/10.1371/journal.pone.0246106.

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Aging is a multifactorial process that involves numerous genetic changes, so identifying anti-aging agents is quite challenging. Age-associated genetic factors must be better understood to search appropriately for anti-aging agents. We utilized an aging-related gene expression pattern-trained machine learning system that can implement reversible changes in aging by linking combinatory drugs. In silico gene expression pattern-based drug repositioning strategies, such as connectivity map, have been developed as a method for unique drug discovery. However, these strategies have limitations such a
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Abdul, Kader Mohiuddin. "Skin Aging & Modern Edge Anti-Aging Strategies." International Journal of Dermatology and Skin Care 1, no. 1 (2019): 08–62. https://doi.org/10.36811/ijdsc.2019.110002.

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Skin is the barrier that segregates the body from the outer environment. Besides protecting the body from water loss and microorganism infection, it has an important cosmetic role. Young and beautiful appearance may have a positive influence on people’s social behavior and reproductive status. Cleopatra, the Egyptian queen is said to have indulged in daily donkey-milk baths, a practice which apparently required over 700 donkeys to accomplish. The alpha hydroxy acids in the milk is believed to be anti-aging and skin-softening agents. Tang-dynasty ruler and sole female emperor of China, Wu
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Zou, Yuming, Pan Pan, and Xiaoxing Yan. "Comparative Analysis of Performance of Water-Based Coatings Prepared by Two Kinds of Anti-Bacterial Microcapsules and Nano-Silver Solution on the Surface of Andoung Wood." Coatings 13, no. 9 (2023): 1518. http://dx.doi.org/10.3390/coatings13091518.

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A nano-silver solution, urea-formaldehyde resin-coated nano-silver solution microcapsules (AgNPS@UF), and melamine-formaldehyde resin-coated chitosan-modified nano-silver solution microcapsules (CS-AgNPS@MF) were added into the coatings at different contents for comparative tests to explore an anti-bacterial agent with the best anti-bacterial properties in the water-based coatings on Andoung wood (Monopetalanthus spp.). As the content of anti-bacterial agents increased, AgNPS@UF had the best anti-bacterial property towards Staphylococcus aureus and Escherichia coli, with anti-bacterial rates o
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He, Yonghan, Jianhui Chang, Dongwen Lv, et al. "Long-Term Clearance of Senescent Cells Prevents the Hematopoietic Stem Cell Aging in Naturally Aged Mice." Blood 134, Supplement_1 (2019): 1204. http://dx.doi.org/10.1182/blood-2019-123159.

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Senescent cells (SnCs) accumulate with age. Genetic or pharmacological clearance of SnCs delays several age-associated disorders and extends the healthspan of both progeroid and wild-type (WT) mice (Baker DJ et al. Nature, 479: 232, 2011; Baker DJ et al. Nature, 530: 184, 2016). In addition, our previous study showed that transient depletion of SnCs could rejuvenated aged hematopoietic stem cells (HSCs) and muscle stem cells in normally aged mice (Chang J et al. Nat Med, 22:78, 2016). These findings suggest that SnCs play a causative role in aging and certain aging-related pathologies, and tha
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Balitaan, Jolleen, Holger Steinbrenner, and Maria Ramos. "Zymography-Based Assay for Screening Potential Anti-Gelatinase Agents using Serratia marcescens Serralysin." SciEnggJ 3, no. 1 (2010): 100–108. http://dx.doi.org/10.54645/dsqa38980.

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Matrix metalloproteinases (MMPs) are a class of over 20 zinc-dependent proteolytic enzymes that have been implicated in the physiologic process of aging and in the pathogenesis of cancer. Specifically, the gelatinases MMP-2 and MMP-9 have been intensively studied in connection with tumor invasion and metastasis, and have been considered as promising targets for cancer treatment. Herein, we introduce a fast, reliable and cost-effective zymography-based assay that can be used routinely for pre-screening agents with potential anti-gelatinolytic activity. Agents which exhibit antigelatinolytic act
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Rachman, Eva Syariefah, Widji Soeratri, and Tristiana Erawati M. "Characteristics and Physical Stability of Nanoemulsion as a Vehicle for Anti-Aging Cosmetics: A Systematic Review." JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA 10, no. 1 (2023): 62–85. http://dx.doi.org/10.20473/jfiki.v10i12023.62-85.

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Background: Skin aging can be overcome by applying anti-aging cosmetics. Many active ingredients that have anti-aging potential are derived from plants, and these materials must be delivered with a sound skin delivery system, namely nanoemulsion. The characteristics of nanoemulsion are closely related to physical stability. Objective: This study aims to conduct a systematic review of in vivo and in vitro study designs to examine the characteristics and physical stability of nanoemulsions used in topical anti-aging cosmetics. Methods: A systematic literature review based on the PRISMA statement
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Zhuang, Chuanyi, Hao Guo, Fengxiang Li, et al. "Study on Adhesion Performance and Aging Strength Degradation Mechanism of SBS Modified Asphalt with Different Anti-Aging Additive." Materials 16, no. 13 (2023): 4881. http://dx.doi.org/10.3390/ma16134881.

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After aging, the adhesiveness of asphalt deteriorates, leading to a reduction in the durability of asphalt mixtures and affecting the service life of asphalt pavements. To enhance the anti-aging performance of asphalt, this study employed the method of melt blending to prepare three types of modified asphalt: graphene/SBS modified asphalt (G/SBSMA), crumb rubber/SBS modified asphalt (CR/SBSMA), and petroleum resin/SBS modified asphalt (PR/SBSMA). Different dosages of the three types of modified asphalt were tested for changes in conventional performance indicators. The optimal dosages of graph
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Cong, Peiliang, Junyan Wang, Weihua Luo, and Yihan Zhang. "Effects of aging on the properties of SBS modified asphalt binders containing anti-aging agents." Construction and Building Materials 302 (October 2021): 124413. http://dx.doi.org/10.1016/j.conbuildmat.2021.124413.

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Cao, Zhilong, Qianlong Hao, Song Xu, Juan Yi, Bochao Zhou, and Haodong Feng. "Stage-Dependent effects of inorganic layered and organic anti-aging agents on asphalt aging resistance." Fuel 400 (November 2025): 135765. https://doi.org/10.1016/j.fuel.2025.135765.

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Rahm, Christina. "Integrative Approaches to Treatments for Anti-aging of the Largest Organ-The Skin." Clinical and Medical Engineering Live 3, no. 1 (2025): 1–5. https://doi.org/10.64030/2997-612x.03.01.10.

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The aging process is reflected not only in front of one's mirror but also deep within the complex cellular mechanisms responsible for health maintenance. In search of an answer to this universal trend towards growing old and related diseases, ROOT started a new path, finding out and using nature's resources to delay aging. The search for efficient antiaging methods is becoming very important in a world where life expectancy and vitality are dominantly considered [1]. However, it goes beyond this desire for youthfulness toward our health and quality of life. Oxidative stress, inflammation, and
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Быков, В. Н., А. Н. Гребенюк, and И. Б. Ушаков. "RADIATION-PROTECTIVE AGENT AND ANTI-AGING AGENTS: RANDOM AND PREDICTABLE MATCHES." Успехи геронтологии, no. 4 (October 20, 2020): 646–56. http://dx.doi.org/10.34922/ae.2020.33.4.003.

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Радиопротекторные и геропротекторные свойства соединений нередко сочетаются, что может быть обусловлено общими механизмами действия: антиоксидантной активностью, повышением устойчивости к клеточному стрессу, ускорением репарации ДНК, предотвращением хронических воспалительных заболеваний и канцерогенеза. В данной работе приведен детальный анализ молекулярнобиологических механизмов действия препаратов, обладающих радиопротекторными и/или геропротекторными свойствами. Описаны общие звенья развития старения и патогенеза заболеваний, связанных с облучением, включающие активацию свободнорадикальных
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González, Salvador, Concepción Parrado, and Ángeles Juarranz. "Introduction to special issue “Recent Advances in Skin Anti-Aging Agents”." Plastic and Aesthetic Research 9 (2022): 32. http://dx.doi.org/10.20517/2347-9264.2022.04.

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UROOJ, F., A. IFTIKHAR, K. MAZHAR, et al. "ANTIOXIDANT ASSESSMENT OF SOME THERAPEUTICALLY IMPORTANT PLANTS AS ANTI-AGING AGENTS." Biological and Clinical Sciences Research Journal 2024, no. 1 (2024): 969. http://dx.doi.org/10.54112/bcsrj.v2024i1.969.

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Skin, the protective outer covering of the body, acts as an insulator between internal and external environments. Skin diseases are a significant concern today, primarily due to oxidative stress. Although synthetic compounds and drugs are available, they often contain toxic and carcinogenic compounds, leading to cancer. Herbal and natural products, rich in natural antioxidants, are preferred as remedies. Objective: To evaluate the antioxidant potential of different solvent extracts at various concentrations from five plants: Aloe barbadensis, Camellia sinensis, Cocos nucifera, Ficus carica, an
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Prasad, Kedar N., Meixia Wu, and Stephen C. Bondy. "Telomere shortening during aging: Attenuation by antioxidants and anti-inflammatory agents." Mechanisms of Ageing and Development 164 (June 2017): 61–66. http://dx.doi.org/10.1016/j.mad.2017.04.004.

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Wang, Yanyan, Xinrong Fan, Jianxia Zhang та ін. "Discovery of β-ionone derived chalcones as potent anti-aging agents". Phytochemistry Letters 53 (лютий 2023): 211–15. http://dx.doi.org/10.1016/j.phytol.2023.01.001.

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Fitriyani, Salsabila Eka Setia Ningrum, and Roihatul Mutiah. "Potential Combination of Dayak onion Eleutherine palmifolia L. and Chrysanthemum flower Chrysanthemum indicum L. as Anti-aging: Network Pharmacology Approach." JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA 11, no. 2 (2024): 219–29. https://doi.org/10.20473/jfiki.v11i22024.219-229.

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Background: An anti-aging agent is a preparation or product used to inhibit skin aging. Aging occurs because of cell damage caused by free radicals. Therefore, anti-aging agents, which contain antioxidants to inhibit oxidative stress caused by free radicals, are needed. Dayak onion (eleutherine palmifolia (L) Merr.) and chrysanthemum flowers (Chrysanthemum indicum L.) have high antioxidant content, which has the potential to inhibit aging. Objective: To determine the anti-aging potential of dayak onion and chrysanthemum flower compounds Methods: Network pharmacology was performed using GeneCar
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Miastkowska, Małgorzata, and Elżbieta Sikora. "Anti-Aging Properties of Plant Stem Cell Extracts." Cosmetics 5, no. 4 (2018): 55. http://dx.doi.org/10.3390/cosmetics5040055.

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Skin aging is a complex process which involves all the layers of the epidermis and dermis. In order to slow skin aging, methods are researched which would strengthen and protect skin stem cells. Science is in search of the right method to stimulate the proliferation of epidermal stem cells. Plant stem cells show outstanding anti-aging properties, as they can, among other activities, stimulate fibroblasts to synthesise collagen, which, in turn, stimulates skin regeneration. One of the most important agents which give anti-aging properties to plant stem cell extracts is kinetin (6-furfuryladenin
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Oliviero Rossi, Cesare, Paolino Caputo, Saltanat Ashimova, Antonio Fabozzi, Gerardino D’Errico, and Ruggero Angelico. "Effects of Natural Antioxidant Agents on the Bitumen Aging Process: An EPR and Rheological Investigation." Applied Sciences 8, no. 8 (2018): 1405. http://dx.doi.org/10.3390/app8081405.

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Bitumen aging is the major factor contributing to the deterioration of the road pavement. Oxidation and volatilization are generally considered as the most important phenomena affecting aging in asphalt paving mixtures. The present study was carried out to investigate whether various antioxidants provided by natural resources such as phospholipids, ascorbic acid as well as lignin from rice husk, could be used to reduce age hardening in asphalt binders. A selected bituminous material was modified by adding 2% w/w of the anti-aging natural additives and subjected to accelerated oxidative aging r
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Ding, Jie, Jiahui Liu, Qingqi Guo, and Na Zhang. "Transcriptomic Approaches to Investigate the Anti-Aging Effects of Blueberry Anthocyanins in a Caenorhabditis Elegans Aging Model." Antioxidants 14, no. 1 (2024): 35. https://doi.org/10.3390/antiox14010035.

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This study investigates the anti-aging effects of various concentrations of blueberry anthocyanins (BA) on the lifespan and health-related phenotypes of Caenorhabditis elegans. Blueberry anthocyanins were administered at concentrations of 50.0 μg/mL, 200.0 μg/mL, and 500.0 μg/mL, and their effects on nematode lifespan, locomotion, pharyngeal pumping rate, and the accumulation of lipofuscin and reactive oxygen species (ROS) were examined. Transcriptomic analysis was conducted to explore the regulatory effects of BA on anti-aging molecular pathways and key genes in C. elegans. Results showed a s
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Lee, Ju Hee, Kee Yang Chung, Dongsik Bang, and Kwang Hoon Lee. "Searching for aging-related proteins in human dermal microvascular endothelial cells treated with anti-aging agents." PROTEOMICS 6, no. 4 (2006): 1351–61. http://dx.doi.org/10.1002/pmic.200500287.

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Garcella, Prilyano, Triyadi Hendra Wijaya, and Dhadhang Wahyu Kurniawan. "Narrative Review: Herbal Nanocosmetics for Anti Aging." JPSCR: Journal of Pharmaceutical Science and Clinical Research 8, no. 1 (2023): 63. http://dx.doi.org/10.20961/jpscr.v8i1.57675.

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<span lang="EN-US">Skin aging is a complex biological process caused by intrinsic and extrinsic factors. There are various approaches to preventing skin aging, one of which is using herbal nanocosmetics. This narrative review aims to determine the natural ingredients, type of nanoformulations, and its effects of herbal nanocosmetics to prevent skin aging. The method used in this study was searching for articles related to herbal nanocosmetics to avoid aging skin through Google Scholar, PubMed, and Science Direct with the keywords herbal plants, anti-aging, herbal cosmetics, cosmetics, na
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Fujinami, Katsuyuki, Katsuaki Dan, Toshiko Tanaka-Kagawa, and Ikuo Kawamura. "Anti-Aging Effects of Polyoxometalates on Skin." Applied Sciences 11, no. 24 (2021): 11948. http://dx.doi.org/10.3390/app112411948.

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Excessive reactive oxygen species (ROS) generation by inflammation and glycation contributes to various aging-related changes in the body. Therefore, inhibiting ROS production can prevent wrinkles, maculae, dullness, and slackness in skin. To assess the anti-aging effects of two polyoxometalates (PMs: VB2 and VB3) on skin, this study investigated whether they ameliorated the anti-aging responses of normal human dermal fibroblasts (NHDF) to oxidative stress due to ad-vanced glycation end products (AGEs) or H2O2 exposure. Compared with the mRNA expression levels of AGE receptors in cells exposed
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Zarei, Farshad, and Abolfazl Abbaszadeh. "Application of Cell Therapy for Anti-Aging Facial Skin." Current Stem Cell Research & Therapy 14, no. 3 (2019): 244–48. http://dx.doi.org/10.2174/1574888x13666181113113415.

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The human skin undergoes the complex process of aging which is prompted by the interplay of intrinsic mechanisms and extrinsic influences. Aging is unavoidable but can be somewhat delayed. Numerous approaches have been developed to slow down facial skin aging process as it is of interest to stake holders in the beauty and fashion world as well as to plastic surgeons. Adipose-derived stem cell [ADSC] and mesenchymal stem cell [MSC] as potential anti-aging agents to some extent have provided a promising and effective alternative in managing skin and facial skin aging. Furthermore, bone marrow-de
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Kintamani, Endang, Irmanida Batubara, Cecep Kusmana, Tatang Tiryana, Edi Mirmanto, and Shadila F. Asoka. "Essential Oil Compounds of Andaliman (Zanthoxylum acanthopodium DC.) Fruit Varieties and Their Utilization as Skin Anti-Aging Using Molecular Docking." Life 13, no. 3 (2023): 754. http://dx.doi.org/10.3390/life13030754.

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Exposure to UV/infrared (IR) radiation is the main extrinsic factor that changes skin morphology and affects the increase in reactive oxygen species (ROS) in skin aging. Ten varieties of andaliman (Zanthoxylum acanthopodium DC.) fruit are presumed to have skin anti-aging compounds via an enzyme-inhibition mechanism. This study aims to compare ten essential oils (EOs) of andaliman fruit varieties, group them according to their varieties, and obtain the chemical components that can be used as potential skin anti-aging agents using molecular docking. EOs were isolated by hydrodistillation, and th
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Gayatri, Yeole* Ajay Baitule Himani Malode Jaydeep Wankhade. "Beyond Beauty: Exploring the Impact of Cosmeceuticals on Early Skin Aging." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3823–34. https://doi.org/10.5281/zenodo.15490334.

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Aging, particularly early or premature aging, is influenced by both genetic and environmental factors. Early skin aging results from changes in the skin’s structure, including collagen and elastin degradation, free radical damage, and hormonal shifts. Environmental elements such as excessive sunlight, poor nutrition, lack of sleep, and smoking accelerate this process. The biological age of the skin can be evaluated by its thickness, elasticity, and moisture levels. Cosmeceuticals, including peptides, vitamins, botanicals, and hydroxy acids, play a significant role in the prevention and t
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Ding, Ai-Jun, Shan-Qing Zheng, Xiao-Bing Huang, et al. "Current Perspective in the Discovery of Anti-aging Agents from Natural Products." Natural Products and Bioprospecting 7, no. 5 (2017): 335–404. http://dx.doi.org/10.1007/s13659-017-0135-9.

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Liu, Quantao, Jinjie Li, and Shuaichao Chen. "Effects of Different Antioxidant Intercalated Layered Double Hydroxides on Anti-Aging Properties of Asphalt Binders." Buildings 14, no. 3 (2024): 593. http://dx.doi.org/10.3390/buildings14030593.

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This research aims to prepare different antioxidant intercalated layered double hydroxides (LDHs) and compare the thermal oxidation and ultraviolet (UV) aging resistances of different modified asphalts. The ion exchange technique was used to intercalate three different antioxidants: 3-(3,5-di-tert-butyl-4-carboxyphenyl) propionic acid, antioxidant 1222, and sodium dibutyl dithiocarbamate (rubber accelerator TP) into the interlayer of LDHs. The morphology, structures, UV blocking, and free radical scavenging properties of different antioxidant intercalated LDHs were characterized, respectively.
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Anestopoulos, Ioannis, Despoina Eugenia Kiousi, Ariel Klavaris, et al. "Surface Active Agents and Their Health-Promoting Properties: Molecules of Multifunctional Significance." Pharmaceutics 12, no. 7 (2020): 688. http://dx.doi.org/10.3390/pharmaceutics12070688.

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Surface active agents (SAAs) are molecules with the capacity to adsorb to solid surfaces and/or fluid interfaces, a property that allows them to act as multifunctional ingredients (e.g., wetting and dispersion agents, emulsifiers, foaming and anti-foaming agents, lubricants, etc.) in a widerange of the consumer products of various industrial sectors (e.g., pharmaceuticals, cosmetics, personal care, detergents, food, etc.). Given their widespread utilization, there is a continuously growing interest to explore their role in consumer products (relevant to promoting human health) and how such inf
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